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Neonatal Jaundice malady
36 genes, 2 tissues, 518 related diseases, 2 phenotypes, 42 articles, clinical trials.

Summaries for Neonatal Jaundice

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44Wikipedia, 22MalaCards
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Wikipedia: Neonatal jaundice or Neonatal hyperbilirubinemia, or Neonatal icterus (from the Greek word...44 more...

MalaCards: Neonatal Jaundice, also known as jaundice neonatal, is related to gilbert syndrome and jaundice. An important gene associated with Neonatal Jaundice is CIRH1A (cirrhosis, autosomal recessive 1A (cirhin)), and among its related pathways are RAR-Gamma-RXR-Alpha Degradation and Fluvastatin Pathway, Pharmacokinetics. The compounds mycophenolic acid and udp glucuronic acid have been mentioned in the context of this disorder. Affiliated tissues include skin and t cells, and related mouse phenotypes are liver/biliary system and homeostasis/metabolism.

Aliases & Descriptions for Neonatal Jaundice

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6Disease Ontology, 8DISEASES, 43UMLS, 32Novoseek , 40SNOMED-CT, 24MeSH
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Aliases & Descriptions:

neonatal jaundice 6 8 43
jaundice neonatal 32
icterus 43

Related Diseases for Neonatal Jaundice

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13GeneCards, 14GeneDecks
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Diseases related to neonatal jaundice by text searches and GeneDecks gene sharing:

(show top 50)    (show all 515)
idRelated DiseaseScoreTop Affiliating Genes
1gilbert syndrome29.4UGT1A1, UGT1A4, UGT1A7, G6PD
2jaundice26.1BTD, BPNT1, CIRH1A, UGT1A1, UGT1A4, GSTM1
3obstructive jaundice25.7IL6, ALB, HMOX1, TNF, RHD
4hepatitis16.9BTD, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5
5congenital nonspherocytic hemolytic anemia13.7PKLR, G6PD
6congenital bile acid synthesis defect13.6AMACR, HSD3B7
7hereditary spherocytosis13.6UGT1A1, RHD, G6PD
8blackwater fever13.5HP, G6PD
9beta thalassemia13.5UGT1A1, RHD, G6PD
10hemoglobinopathy13.5BTD, HP, G6PD
11hereditary elliptocytosis13.4HP, RHD, G6PD
12intrahepatic cholestasis13.4CIRH1A, AMACR, HSD3B7, SLCO1B1
13congenital hemolytic anemia13.4HP, TPI1, PKLR, G6PD
14favism13.4HP, ACP1, G6PD
15elliptocytosis13.4HP, RHD, G6PD
16heme oxygenase-1 deficiency13.4HP, HMOX1
17glucosephosphate dehydrogenase deficiency13.3UGT1A1, HP, G6PD, SLCO1B1
18kawasaki disease13.3UGT1A9, HMOX1
19crigler najjar syndrome, type 213.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
20crigler-najjar syndrome13.3UGT1A1, UGT1A4, UGT1A6, UGT1A9
21alpha thalassemia13.2UGT1A1, HP, G6PD
22spherocytosis13.2UGT1A1, HP, PKLR, RHD, G6PD
23plasmodium falciparum malaria13.1IL10, HP, TPI1, G6PD
24hemolytic anemia13.0UGT1A1, HP, TPI1, PKLR, RHD, G6PD
25punctate inner choroidopathy13.0IL10, TNF
26central nervous system leukemia13.0IL1B, TNF
27bilirubin metabolic disorder13.0BTD, TPI1, NR1I3, ACP1, G6PD
28hydrops fetalis12.9ALB, RHD, G6PD
29cholelithiasis12.9UGT1A1, UGT1A6, HP, HMOX1, G6PD
30pulmonary arteriovenous malformation12.9ALB, HMOX1
31spotted fever12.9IL10, TNF, G6PD
32pulmonary tuberculosis12.8IL10, HP, ACP1, PGM1
33malaria12.8IL10, TNF, G6PD
34bladder cancer susceptibility12.8GSTM1, GSTT1, TNF
35diabetic polyneuropathy12.8GSTM1, GSTT1, TNF
36gallbladder disease12.8UGT1A1, IL10, ALB
37factor v leiden thrombophilia12.7AMACR, HMOX2, RHD, ACP1, OXT
38trachoma12.7IL10, HP, TNF
39migraine without aura12.7GSTM1, GSTT1, TNF
40poliomyelitis12.7IL10, TNF, RHD
41senile cataract12.7GSTM1, GSTT1, ALB, G6PD
42colorectal cancer12.7UGT1A1, GSTM1, GSTT1, TNF
43typhoid fever12.7IL1B, TNF, RHD, G6PD
44panuveitis12.6IL10, TNF
45herpes zoster12.6IL10, HP, TNF
46euthyroid sick syndrome12.6IL1B, IL6
47sepsis12.6IL10, TNF
48kidney cancer12.6GSTM1, GSTT1, AMACR, TNF
49staphylococcal toxic shock syndrome12.6IL1B, TNF
50porphyria cutanea tarda12.6GSTM1, GSTT1, ALB

Graphical network of the top 20 diseases related to neonatal jaundice:



Graphical network of diseases related to neonatal jaundice

Clinical Features for Neonatal Jaundice

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Drugs & Therapeutics for Neonatal Jaundice

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for neonatal jaundice

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Genetic Tests for Neonatal Jaundice

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Anatomical Context for Neonatal Jaundice

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22MalaCards
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MalaCards organs/tissues related to neonatal jaundice:

22
Skin, T cells

Phenotypes for genes affiliated with Neonatal Jaundice

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25MGI
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MGI Mouse Phenotypes related to neonatal jaundice:

25
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1liver/biliary system phenotypeMP:00053709.1IL6, AMACR, HSD3B7, NR1I3
2homeostasis/metabolism phenotypeMP:00053766.5BTD, OXT, G6PD, RHD, NR1I3, TPI1

Publications for genes affiliated with Neonatal Jaundice

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35PubMed
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Articles related to neonatal jaundice:

(show all 42)
idTitleAuthorsYearAffiliating Genes
1Polymorphic Variants of UGT1A1 in Neonatal Jaundice i n Southern Brazil. (20061399)Carvalho C.G.... Giugliani R.2010UGT1A1
2Glucose-6-phosphate dehydrogenase and red cell pyruva te kinase deficiency in neonatal jaundice cases in egypt. (20426517)Abdel Fattah M.... Kamal S.2010G6PD
3A polymorphic mutation, c.-3279T>G, in the UGT1A1 promoter is a risk factor for neonatal jaundice in the Malay population. (20057336)Yusoff S.... Van Rostenberghe H.2010UGT1A1
4A prolonged neonatal jaundice associated with a rare G6PD mutation. (19422023)Minucci A.... Capoluongo E.2009G6PD
5Relationship between glucose-6-phosphate dehydrogena se gene mutations and neonatal jaundice in Naning, Guangxi (20113600)Zhong D.N.... Wei L.M.2009G6PD
6Are glutathione S-transferase gene polymorphisms linked to neonatal jaundice? (17318621)Muslu N.... Atik U.2008GSTT1, GSTM1
7Relation between neonatal jaundice and oncostatin M, hepatocyte growth factor and soluble gp130 levels in umbilical cord. (18972232)Nakatsukasa H.... Hiramatsu Y.2008OSM
8Can haptoglobin be an indicator for the early diagnosis of neonatal jaundice? (19021267)Cakmak A.... Erel O.2008HP
9Efficacy of clofibrate on severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency (a randomized clinical trial). (18564698)Zahedpasha Y.... Kamali A.A.2008G6PD
10Cytokines in human colostrum and neonatal jaundice. (17597660)Zanardo V.... Plebani M.2007TNF, IL6, IL1B
11Red cell pyruvate kinase deficiency in neonatal jaundice cases in India. (17127778)Kedar P.S.... Mohanty D.2006G6PD
12Neonatal jaundice and bilirubin UDP-glucuronosyl transferase 1A1 gene polymorphism in Turkish patients. (16623861)Babaoglu M.O.... Bozkurt A.2006UGT1A1
13Role of genetic factors in occurrence of neonatal jaundice in Guangxi region (16255851)Fu W.P.... Liu Y.2005G6PD, SLCO1B1, UGT1A1
14An update on the prevalence of glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Tehran neonates. (14972648)Abolghasemi H.... Amid A.2004G6PD
15The effect of neonatal jaundice on biotinidase activity. (12706308)Schulpis K.H.... Costalos C.2003BTD
16Interest in the study of genetic variants of the promoter region of the UGT1A1 gene in neonatal jaundice (11827650)Seco M.L.... Baiget M.2002UGT1A1
17Neonatal jaundice--traditional Chinese medicine approach. (11803427)Fok T.F.2001G6PD
18Glucose-6-phosphate dehydrogenase et neonatal jaundice (11317924)Badens C.... Lena-Russo D.2001G6PD
19Investigation of prolonged neonatal jaundice. (10914965)Hannam S.... Rennie J.M.2000G6PD
20Glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice in Al-Hofuf area. (17337961)Al-Omran A.... John T.B.1999G6PD
21A variant TATA box in the bilirubin UDP-glucuronosyltransferase 1 gene promoter does not contribute to neonatal jaundice in the Japanese population. (10507878)Waku S.... Sumino K.1999UGT1A1
22Severe neonatal jaundice. Definition and management (9809164)Labrune P.1998ALB
23Gilbert syndrome accelerates development of neonatal jaundice. (9580766)Bancroft J.D.... Gourley G.R.1998UGT1A1
24The preliminary study on prevention and treatment of neonatal jaundice (9596945)Xia Z.... Li Y.1997HMOX1, HMOX2
25Can severe neonatal jaundice be prevented by neonatal screening for glucose-6-phosphate dehydrogenase deficiency?--a review of evidence. (8942026)Chuu W.M.... Lin K.S.1996G6PD
26Neonatal jaundice and molecular mutations in glucose-6-phosphate dehydrogenase deficient newborn infants. (8571933)Huang C.S.... Tang T.K.1996G6PD
27G6PD NanKang (517 T-->C; 173 Phe-->Leu): a new Chinese G6PD variant associated with neonatal jaundice. (8807322)Chen H.L.... Tang T.K.1996G6PD
28The negative heritability of neonatal jaundice. (8835092)Haldane J.B.1996RHD
29Neonatal jaundice, aflatoxins and naphthols: report of a study in Ibadan, Nigeria. (7677410)Sodeinde O.... Hendrickse R.G.1995G6PD
30Neonatal jaundice in Qatif: The role of glucose-6-phosphate dehydrogenase deficiency in the etiology among outpatient cases. (17589001)Al-Dabbous I.A.... Al-Khater N.S.1995G6PD
31Enzyme deficiencies in neonates with jaundice. (8710395)Casado A.... De La Torre R.1995G6PD
32Role of hemolysis in neonatal jaundice associated with glucose-6 phosphate dehydrogenase deficiency. (7472840)Seidman D.S.... Gale R.1995G6PD
33Glucose-6-phosphate dehydrogenase deficiency in the newborn: its prevalence and relation to neonatal jaundice. (8629093)Tanphaichitr V.S.... Suvatte V.1995G6PD
34Erythrocyte glucose 6 phosphate dehydrogenase deficiency and neonatal jaundice. (8714619)Rehman H.... Ahmad A.1995G6PD
35Severe neonatal jaundice associated with glucose-6-phosphate dehydrogenase deficiency: pathogenesis and global epidemiology. (7919613)Valaes T.1994G6PD
36Do drugs in pregnancy modify neonatal jaundice? (8368029)Meisel P.... Meisel M.1993OXT
37Association between glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice: interaction with multiple risk factors. (1468858)Yu M.W.... Chen C.J.1992G6PD
38Neonatal jaundice in Asia. (1596589)Ho N.K.1992G6PD
39Screening for glucose-6-phosphate dehydrogenase deficiency can prevent severe neonatal jaundice. (1283668)Mallouh A.A.... Hamdan J.A.1992G6PD
40Role of genetic variability in neonatal jaundice. A prospective study on full-term, blood group-compatible infants. (1765134)Lucarini N.... Bottini E.1991PGM1
41Neonatal jaundice. A second 4-year experience in Toa Payoh Hospital (1986-1989). (1812331)Ho N.K.1991G6PD
42Neonatal jaundice among Nigerian preterm infants. (2083201)Owa J.A.... Dawodu A.H.1990G6PD

Expression for genes affiliated with Neonatal Jaundice

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Neonatal Jaundice

Pathways for genes affiliated with Neonatal Jaundice

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36QIAGEN, 34PharmGKB, 38Reactome, 41Thomson Reuters, 10EMD Millipore, 20KEGG
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Pathways related to neonatal jaundice according to GeneDecks:

(show all 46)
idPathwayScoreTop Affiliating Genes
1RAR-Gamma-RXR-Alpha Degradation3610.5OSM
2Fluvastatin Pathway, Pharmacokinetics3410.3SLCO1B1, UGT1A3, UGT1A1
3Glucuronidation3810.3UGT1A6, UGT1A4, UGT1A1
4Atorvastatin/Lovastatin/Simvastatin Pathway, Pharmacokinetics3410.2UGT1A1, UGT1A3, SLCO1B1
5Benzo[a]pyrene metabolism4110.2UGT1A9, UGT1A6, UGT1A10
6Tamoxifen Pathway, Pharmacokinetics3410.2UGT1A8, UGT1A4, UGT1A3, UGT1A10
7Benzo[a]pyrene metabolism1010.2UGT1A9, UGT1A6, UGT1A10
8Statin Pathway - Generalized, Pharmacokinetics3410.2UGT1A1, UGT1A3, SLCO1B1
9Irinotecan Pathway, Pharmacokinetics3410.2UGT1A1, UGT1A10, UGT1A9, SLCO1B1
10Phenytoin Pathway, Pharmacokinetics3410.1UGT1A1, UGT1A4, UGT1A6, UGT1A9
11Estrogen Metabolism Pathway3410.0UGT1A1, UGT1A3, UGT1A4, UGT1A8, UGT1A9
12Acetaminophen metabolism4110.0UGT1A9, UGT1A6, UGT1A3, UGT1A10, UGT1A1
13Acetaminophen metabolism1010.0UGT1A9, UGT1A6, UGT1A3, UGT1A10, UGT1A1
14Mycophenolic acid Pathway, Pharmacokinetics349.9SLCO1B1, UGT1A9, UGT1A8, UGT1A7, UGT1A10
15Heme degradation389.9HMOX1, HMOX2
16Valproic Acid Pathway, Pharmacokinetics349.8UGT1A9, UGT1A8, UGT1A6, UGT1A4, UGT1A3, UGT1A10
172-Naphthylamine and 2-Nitronaphtalene metabolism109.8UGT1A9, UGT1A8, UGT1A6, UGT1A4, UGT1A3, UGT1A1
182-Naphthylamine and 2-Nitronaphtalene metabolism419.8UGT1A9, UGT1A8, UGT1A6, UGT1A4, UGT1A3, UGT1A1
19Irinotecan Pathway, Pharmacodynamics349.7UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6, UGT1A8
20Ascorbate and aldarate metabolism209.4UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A5, UGT1A4
21Pentose and glucuronate interconversions209.4UGT1A8, UGT1A7, UGT1A6, UGT1A5, UGT1A4, UGT1A3
22Other types of O-glycan biosynthesis209.4UGT1A1, UGT1A10, UGT1A9, UGT1A8, UGT1A7, UGT1A6
23Steroid hormone biosynthesis209.4UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A5, UGT1A4
24Drug metabolism - other enzymes209.4UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5, UGT1A6
25Retinol metabolism209.4UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A5, UGT1A4
26Starch and sucrose metabolism209.2PGM1, UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A5
27Porphyrin and chlorophyll metabolism209.0UGT1A1, HMOX2, HMOX1, UGT1A9, UGT1A8, UGT1A7
28Metabolism of xenobiotics by cytochrome P450208.7UGT1A5, UGT1A4, UGT1A3, UGT1A10, UGT1A1, UGT1A6
29Drug metabolism - cytochrome P450208.7GSTT1, GSTM1, UGT1A9, UGT1A8, UGT1A7, UGT1A6
30Immune response IL-1 signaling pathway108.5TNF, HMOX1, IL6, IL1B
31Immune response_IL-1 signaling pathway418.5TNF, HMOX1, IL6, IL1B
32Cytokine Network368.4IL10, IL1B, IL6, TNF
33African trypanosomiasis208.4TNF, IL6, IL1B, IL10
34Malaria208.4IL10, IL1B, IL6, TNF
35Pertussis208.2TNF, IL6, IL1B, IL10
36MIF Mediated Glucocorticoid Regulation368.2OSM, TNF, IL6, IL1B, IL10
37MIF Regulation of Innate Immune Cells368.1IL10, IL1B, IL6, TNF, OSM
38IL-10 Pathway368.1TNF, HMOX1, IL6, IL1B, IL10
39Chagas disease (American trypanosomiasis)208.1TNF, IL6, IL1B, IL10
40all-trans-Retinoic Acid Signaling in Brain368.1IL10, IL1B, IL6, TNF, OSM
41PEDF Induced Signaling368.1OSM, TNF, IL6, IL1B, IL10
42Metabolic pathways208.0UGT1A9, AMACR, HSD3B7, TPI1, PKLR, G6PD
43IL-6 Pathway368.0IL10, IL1B, IL6, TNF, OSM
44STAT3 Pathway367.9OSM, TNF, IL6, IL1B, IL10
45Endothelin-1 Signaling Pathway367.9IL10, IL1B, IL6, TNF, OSM
46Amoebiasis207.8TNF, IL6, IL1B, IL10

Compounds for genes affiliated with Neonatal Jaundice

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32Novoseek , 9DrugBank, 18HMDB, 34PharmGKB, 42Tocris Bioscience
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Compounds related to neonatal jaundice according to GeneDecks:

(show top 50)    (show all 193)
idCompoundScoreTop Affiliating Genes
1mycophenolic acid32 9 9 12.3UGT1A7, UGT1A8, UGT1A10
2udp glucuronic acid32 9.9UGT1A8, UGT1A10, UGT1A1, UGT1A6
3aspartate32 9.8OXT, RHD, HP
4p-nitrophenol32 9 9 11.8UGT1A9, UGT1A6, UGT1A4, UGT1A3, UGT1A1
5glucuronide32 9.7UGT1A7, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6
6n-hydroxy phip32 9.7UGT1A1, UGT1A10, UGT1A4, UGT1A6, UGT1A7, UGT1A8
7trifluoperazine32 9 9 11.5UGT1A9, UGT1A1, UGT1A4, UGT1A6, ACP1
8ethyl glucuronide32 18 10.5UGT1A3, UGT1A10, UGT1A1, UGT1A7, UGT1A8, UGT1A9
9acetaminophen32 34 9 18 9 13.5UGT1A9, UGT1A4, UGT1A1, G6PD, NR1I3, UGT1A7
10imipramine32 34 9 18 9 13.5UGT1A4, UGT1A9, UGT1A10, UGT1A1, UGT1A8, UGT1A3
11uridine diphosphate32 9.5UGT1A4, UGT1A1, SLCO1B1, UGT1A9, UGT1A7, UGT1A6
12sn-3834 9.4UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A5, UGT1A6
13codeine32 34 9 18 9 13.4UGT1A5, UGT1A6, UGT1A7, UGT1A8, UGT1A9, UGT1A4
14bilirubin diglucuronide32 18 10.4UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A9, UGT1A8
153-alpha-androstanediol glucuronide32 18 10.4UGT1A1, UGT1A10, UGT1A4, UGT1A5, UGT1A6, UGT1A7
16androsterone glucuronide32 18 10.4UGT1A1, UGT1A10, UGT1A9, UGT1A8, UGT1A4, UGT1A3
172-methoxyestradiol32 18 10.4UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A5, UGT1A4
18(23S)-23,25-dihdroxy-24-oxovitamine D3 23-(beta-glucuronide)18 9.4UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A5, UGT1A4
19aldosterone 18-glucuronide32 18 10.4UGT1A1, UGT1A10, UGT1A9, UGT1A8, UGT1A7, UGT1A6
20Estriol9 18 9 11.4UGT1A8, UGT1A7, UGT1A6, UGT1A9, UGT1A1, UGT1A10
21etiocholanolone32 18 10.4UGT1A6, UGT1A9, UGT1A8, UGT1A7, UGT1A5, UGT1A4
22diclofenac32 34 9 9 12.4UGT1A3, UGT1A4, UGT1A6, UGT1A9, ALB, UGT1A1
23glucose 6-phosphate32 18 10.3UGT1A1, PGM1, SLCO1B1, G6PD, TPI1, HP
24cellulose acetate32 9.2ALB, HP, G6PD, ACP1, PGM1
25mycophenolate mofetil32 9 9 11.2UGT1A10, UGT1A1, UGT1A9, IL10, UGT1A8, ALB
26benzidine32 9.1UGT1A6, UGT1A4, UGT1A1, HP, UGT1A9, GSTT1
27flurbiprofen32 34 9 9 12.1HP, ALB, IL1B, UGT1A9, UGT1A3, UGT1A1
28benzo(a)pyrene32 9.1GSTT1, UGT1A1, UGT1A6, UGT1A7, UGT1A9, GSTM1
29phenobarbital32 9 9 11.0G6PD, SLCO1B1, UGT1A1, HMOX1, NR1I3, GSTM1
30nicotine32 34 9 9 12.0OXT, UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A4
31morphine32 9 9 11.0UGT1A9, OXT, UGT1A6, UGT1A8, UGT1A4, UGT1A3
32valproic acid32 34 9 18 9 13.0UGT1A9, UGT1A6, UGT1A7, UGT1A10, UGT1A1, UGT1A8
33ascorbic acid32 18 10.0G6PD, GSTM1, GSTT1, ACP1, OXT
34propofol32 9 9 10.8UGT1A8, UGT1A1, UGT1A10, UGT1A3, UGT1A6, UGT1A9
35cotinine32 18 9.8UGT1A10, UGT1A3, UGT1A4, UGT1A6, UGT1A7, UGT1A8
36estradiol32 9 18 9 11.6UGT1A5, UGT1A1, UGT1A10, UGT1A3, UGT1A4, UGT1A6
37thyroxine32 18 9.5G6PD, SLCO1B1, HP, ALB, IL10, UGT1A1
38estrone32 9 18 9 11.4UGT1A7, UGT1A8, UGT1A9, ALB, NR1I3, SLCO1B1
39estrogen32 8.4NR1I3, UGT1A1, UGT1A10, OXT, G6PD, ACP1
40testosterone32 9 18 9 11.0AMACR, NR1I3, G6PD, OXT, UGT1A4, GSTM1
41ibuprofen32 9 18 9 11.0IL1B, UGT1A1, UGT1A3, IL6, ALB, UGT1A9
42taurine chloramine32 7.9IL1B, TNF, HMOX1, IL6
438-isoprostane32 7.9HMOX1, IL10, IL6, TNF, HP
44curcumin32 7.7TNF, HMOX1, IL6, IL1B, ACP1, UGT1A7
45troglitazone32 42 9 9 10.5SLCO1B1, TNF, IL6, IL1B, UGT1A9, UGT1A8
46indomethacin32 9 9 9.1OSM, ACP1, HMOX1, ALB, IL6, IL1B
47lactate32 6.9BTD, IL6, ALB, G6PD, TNF, TPI1
48methotrexate32 34 42 9 9 10.8IL1B, SLCO1B1, OXT, IL10, TNF, ALB
49dexamethasone32 42 34 9 9 10.5TNF, ACP1, NR1I3, HMOX1, HP, AMACR
50retinoic acid32 42 18 7.7IL1B, IL6, AMACR, UGT1A5, UGT1A1, UGT1A8

GO Terms for genes affiliated with Neonatal Jaundice

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12Gene Ontology
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Cellular components related to neonatal jaundice according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum membraneGO:0057898.1UGT1A1, HMOX2, HMOX1, HSD3B7, UGT1A9, UGT1A8
2extracellular spaceGO:0056156.1OXT, TNF, HMOX1, HP, ALB, IL6

Biological processes related to neonatal jaundice according to GeneDecks:

(show all 29)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of steroid metabolic processGO:04593910.4UGT1A1, UGT1A8
2heme oxidationGO:00678810.3HMOX1, HMOX2
3negative regulation of fatty acid metabolic processGO:04592210.3UGT1A9, UGT1A8, UGT1A7
4heme catabolic processGO:04216710.2UGT1A1, HMOX1, HMOX2
5porphyrin-containing compound metabolic processGO:00677810.2HMOX2, HMOX1, UGT1A1
6chronic inflammatory response to antigenic stimulusGO:00243910.1IL1B
7negative regulation of catalytic activityGO:04308610.1UGT1A1, UGT1A7, UGT1A8, UGT1A9
8drug metabolic processGO:01714410.1UGT1A9, UGT1A8, UGT1A7, UGT1A1
9flavone metabolic processGO:05155210.0UGT1A1, UGT1A10, UGT1A7, UGT1A8, UGT1A9
10xenobiotic glucuronidationGO:05269710.0UGT1A9, UGT1A8, UGT1A7, UGT1A3, UGT1A1
11flavonoid glucuronidationGO:05269610.0UGT1A9, UGT1A8, UGT1A7, UGT1A1, UGT1A3
12coumarin metabolic processGO:00980410.0UGT1A8, UGT1A7
13retinoic acid metabolic processGO:04257310.0UGT1A9, UGT1A8, UGT1A7, UGT1A3, UGT1A1
14metabolic processGO:00815210.0UGT1A9, UGT1A6, UGT1A5, UGT1A3, UGT1A10
15bile acid metabolic processGO:0082069.7SLCO1B1, HSD3B7, ALB, AMACR
16receptor biosynthetic processGO:0328009.6TNF, IL10
17positive regulation of calcidiol 1-monooxygenase activityGO:0605599.6TNF, IL1B
18sequestering of triglycerideGO:0307309.5TNF, IL1B
19xenobiotic metabolic processGO:0068059.4GSTM1, UGT1A9, UGT1A6, UGT1A5, UGT1A4, UGT1A1
20glucose metabolic processGO:0060069.4TPI1, TNF, PKLR, PGM1
21positive regulation of chemokine biosynthetic processGO:0450809.3IL1B, HMOX1, TNF
22positive regulation of heterotypic cell-cell adhesionGO:0341169.3TNF, IL1B
23response to activityGO:0148239.1IL10, TNF, OXT
24negative regulation of cytokine secretion involved in immune responseGO:0027409.1IL10, TNF
25positive regulation of smooth muscle cell proliferationGO:0486618.7IL6, HMOX1, TNF
26positive regulation of interleukin-6 productionGO:0327558.6TNF, IL6, IL1B
27positive regulation of sequence-specific DNA binding transcription factor activityGO:0510918.3TNF, IL6, IL1B, IL10
28response to glucocorticoid stimulusGO:0513848.0OXT, TNF, IL6, IL1B, IL10
29small molecule metabolic processGO:0442817.4HMOX1, HMOX2, TPI1, PKLR, G6PD, SLCO1B1

Molecular functions related to neonatal jaundice according to GeneDecks:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1heme oxygenase (decyclizing) activityGO:00439210.0HMOX1, HMOX2
2enzyme inhibitor activityGO:0048579.7UGT1A9, UGT1A8, UGT1A7, UGT1A1
3retinoic acid bindingGO:0019729.2UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A4, UGT1A3
4glucuronosyltransferase activityGO:0150209.2UGT1A1, UGT1A9, UGT1A10, UGT1A3, UGT1A4, UGT1A5
5protein heterodimerization activityGO:0469829.1UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A4, UGT1A3
6enzyme bindingGO:0198998.9HMOX1, UGT1A9, UGT1A8, UGT1A7, UGT1A6, UGT1A4
7protein homodimerization activityGO:0428038.7G6PD, HMOX1, UGT1A9, UGT1A8, UGT1A7, UGT1A6
8cytokine activityGO:0051257.6IL10, IL1B, IL6, TNF, OSM

Sources for Neonatal Jaundice

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2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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