MCID: NNT012
MIFTS: 39

Neonatal Jaundice malady

Skin diseases category

Summaries for Neonatal Jaundice

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66Wikipedia, 34MalaCards
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Wikipedia:66 Neonatal jaundice or Neonatal hyperbilirubinemia, or Neonatal icterus (from the Greek word ???????),... more...

MalaCards: Neonatal Jaundice, also known as jaundice neonatal, is related to kernicterus and gilbert syndrome. An important gene associated with Neonatal Jaundice is G6PD (glucose-6-phosphate dehydrogenase), and among its related pathways are Glucose / Energy Metabolism and Metabolism of porphyrins. The compounds zinc protoporphyrin and phenol have been mentioned in the context of this disorder. Affiliated tissues include skin, breast and brain.

Aliases & Classifications for Neonatal Jaundice

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9Disease Ontology, 11DISEASES, 63UMLS, 46Novoseek, 59SNOMED-CT, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

neonatal jaundice 9 11 63
jaundice neonatal 46


External Ids:

Disease Ontology9 DOID:2383
MeSH36 D007567

Related Diseases for Neonatal Jaundice

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Neonatal Jaundice:



Diseases related to neonatal jaundice

Symptoms for Neonatal Jaundice

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Drugs & Therapeutics for Neonatal Jaundice

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Neonatal Jaundice

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Anatomical Context for Neonatal Jaundice

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34MalaCards
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MalaCards organs/tissues related to Neonatal Jaundice:

34
Skin, Breast, Brain, Eye, Colon

Animal Models for Neonatal Jaundice or affiliated genes

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Publications for Neonatal Jaundice

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53PubMed
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Articles related to Neonatal Jaundice:

(show top 50)    (show all 507)
idTitleAuthorsYear
1
Fluorescence Excitation Spectrum of Bilirubin in Blood: A Model for the Action Spectrum for Phototherapy of Neonatal Jaundice. (23998276)
2013
2
Influence of Changes in the Evaluation of Neonatal Jaundice. (23616073)
2013
3
Evaluation of maternal knowledge level about neonatal jaundice. (22082141)
2012
4
Bilirubin rebound after intensive phototherapy for neonatal jaundice. (20019393)
2010
5
Twists and turns in phototherapy for neonatal jaundice. (20528792)
2010
6
Maternal experience with neonatal jaundice. (20032753)
2010
7
Neonatal adrenal hemorrhage presenting as late onset neonatal jaundice. (20419026)
2009
8
Knowledge, attitude and behaviour of mothers on neonatal jaundice. (19157319)
2008
9
Prolonged neonatal jaundice and the diagnosis of biliary atresia: a single-center analysis of trends in age at diagnosis and outcomes. (18443020)
2008
10
Are glutathione S-transferase gene polymorphisms linked to neonatal jaundice? (17318621)
2008
11
Letter to the Editors: the burden of neonatal jaundice and sepsis in developing countries. (16553919)
2006
12
Neonatal jaundice. (15652016)
2004
13
Breast-feeding, neonatal jaundice and kernicterus. (12208098)
2002
14
Pharmacological interventions for the treatment of neonatal jaundice. (12208095)
2002
15
Spectrum of outcome in infants with extreme neonatal jaundice. (11519982)
2001
16
Managing the assessment of neonatal jaundice: importance of timing. (11105424)
2000
17
Neonatal jaundice, animal-based injuries, and immunizations. (9757374)
1998
18
Comparison technetium of Tc-99m disofenin cholescintigraphy with ultrasonography in the differentiation of biliary atresia from other forms of neonatal jaundice. (9035206)
1997
19
Neonatal jaundice due to ABO incompatibility in Sri Lankan. (10830015)
1996
20
Can severe neonatal jaundice be prevented by neonatal screening for glucose-6-phosphate dehydrogenase deficiency?--a review of evidence. (8942026)
1996
21
Neonatal jaundice, aflatoxins and naphthols: report of a study in Ibadan, Nigeria. (7677410)
1995
22
Neonatal jaundice. (7824404)
1994
23
Etiology of neonatal jaundice at Shimla. (7875794)
1994
24
Animal-induced injuries and disease, neonatal jaundice, viral infections, and immunizations. (8374681)
1993
25
Neonatal jaundice: update on phototherapy management. (8363337)
1993
26
Treating neonatal jaundice with phenobarbitone: the inadvertant administration of significant doses of ethyl alcohol. (1739339)
1992
27
Value of bile acid determination for the diagnosis of neonatal jaundice. (2102973)
1990
28
Management of neonatal jaundice. (2683113)
1989
29
Neonatal jaundice. (3281408)
1988
30
Neonatal jaundice in the home: assessment with a noninvasive device. (3681515)
1987
31
Sunburn from the treatment of neonatal jaundice. (3719406)
1986
32
Free and erythrocyte-bound bilirubin in neonatal jaundice. (3751548)
1986
33
123I BSP scanning in neonatal jaundice. (3566138)
1986
34
Management of neonatal jaundice. (3960414)
1986
35
Neonatal jaundice among full term infants in Riyadh: a prospective study of 190 hospital admissions. (4092624)
1985
36
Bupivacaine alters red blood cell properties: a possible explanation for neonatal jaundice associated with maternal anesthesia. (4000759)
1985
37
Blood brain barrier in neonatal jaundice. (3843560)
1985
38
Chemoprevention of neonatal jaundice: potency of tin-protoporphyrin in an animal model. (6896768)
1982
39
The use of diethyl-IDA Tc 99m clearance curves in the differentiation of biliary atresia from other forms of neonatal jaundice. (7063701)
1982
40
Hepatobiliary scintigraphy with 99mTc-PIPIDA in the evaluation of neonatal jaundice. (6787555)
1981
41
Simultaneous 99mTc-P-butyl-IDA and 131I-rose bengal scintigraphy in neonatal jaundice. (7355225)
1980
42
Early onset of homozygous beta o thalassaemia associated with neonatal jaundice. (570377)
1979
43
Factors influencing the incidence of neonatal jaundice. (647211)
1978
44
Phototherapy for neonatal jaundice in erythrocyte glucose-6-phosphate dehydrogenase-deficient infants. (559284)
1977
45
Red cell metabolism and severe neonatal jaundice in West Malaysia. (409030)
1977
46
Red cell potassium levels in neonatal jaundice --a preliminary study. (859375)
1977
47
Phototherapy for neonatal jaundice in rural Africa. (841688)
1977
48
Erythrocyte glucose-6-phosphate dehydrogenase deficiency and neonatal jaundice. (868519)
1977
49
Oxytocin and neonatal jaundice. (974702)
1976
50
Cytomegalic inclusion disease: another cause for neonatal jaundice. (13611436)
1959

Variations for Neonatal Jaundice

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Expression for genes affiliated with Neonatal Jaundice

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neonatal Jaundice

Search GEO for disease gene expression data for Neonatal Jaundice.

Pathways for genes affiliated with Neonatal Jaundice

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Sources:
51PathCards, 5Cell Signaling Technology, 56Reactome, 39NCBI BioSystems Database, 31KEGG
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Pathways related to Neonatal Jaundice according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5HMOX2, G6PD
2
Show member pathways
tetrapyrrole biosynthesis39
heme degradation39
Heme Biosynthesis39
heme biosynthesis39
heme biosynthesis from uroporphyrinogen-III I39
9.3HMOX2, UGT1A1
3
Show member pathways
8.1HMOX2, G6PD, HSD3B7, UGT1A1

Compounds for genes affiliated with Neonatal Jaundice

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46Novoseek, 25HMDB, 3BitterDB, 52PharmGKB, 12DrugBank, 30IUPHAR
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Compounds related to Neonatal Jaundice according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1zinc protoporphyrin469.7HMOX2, G6PD
2phenol46 2510.6UGT1A1, G6PD
3acetaminophen46 3 52 25 1213.6G6PD, UGT1A1
4phenobarbital46 30 52 1212.5G6PD, UGT1A1
5glucose 6-phosphate46 2510.5UGT1A1, G6PD
6egcg469.5G6PD, UGT1A1
7chloramphenicol46 3 52 1212.4G6PD, UGT1A1
8thyroxine46 2510.3UGT1A1, G6PD
9carbon469.2HMOX2, G6PD
10nadh46 25 1210.9HMOX2, G6PD, HSD3B7
11estrogen468.9HMOX2, G6PD, UGT1A1

GO Terms for genes affiliated with Neonatal Jaundice

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17Gene Ontology
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Cellular components related to Neonatal Jaundice according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1endoplasmic reticulum membraneGO:0057898.5HMOX2, HSD3B7, UGT1A1

Biological processes related to Neonatal Jaundice according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heme catabolic processGO:0421679.2HMOX2, UGT1A1
2porphyrin-containing compound metabolic processGO:0067789.0HMOX2, UGT1A1
3small molecule metabolic processGO:0442818.1HMOX2, G6PD, HSD3B7, UGT1A1

Products for genes affiliated with Neonatal Jaundice

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Sources for Neonatal Jaundice

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet