MCID: NNT021
MIFTS: 28

Neonatal Meningitis malady

Categories: Rare diseases

Aliases & Classifications for Neonatal Meningitis

Aliases & Descriptions for Neonatal Meningitis:

Name: Neonatal Meningitis 50 69
Meningitis, Neonatal 50

Classifications:



Summaries for Neonatal Meningitis

MalaCards based summary : Neonatal Meningitis, also known as meningitis, neonatal, is related to meningitis and peritoneal mesothelioma. An important gene associated with Neonatal Meningitis is PPARG (Peroxisome Proliferator Activated Receptor Gamma), and among its related pathways/superpathways are Pathways in cancer and Glucose / Energy Metabolism. The drugs Gentamicins and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include brain and breast.

Wikipedia : 71 Neonatal meningitis is a serious medical condition in infants. Meningitis is an inflammation of the... more...

Related Diseases for Neonatal Meningitis

Diseases related to Neonatal Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
id Related Disease Score Top Affiliating Genes
1 meningitis 10.7
2 peritoneal mesothelioma 9.8 PPARG SLC2A1
3 non-distal monosomy 10q 9.8 PPARG SLC2A1
4 brain stem glioma 9.7 PPARG SLC2A1
5 influenza 9.7
6 haemophilus influenzae 9.6
7 arachnoiditis 9.6
8 acute cystitis 9.6
9 cystitis 9.6
10 cerebritis 9.6
11 neuhauser eichner opitz syndrome 9.6 CD47 PPARG SLC2A1
12 bacteremia 9.5
13 diabetes insipidus 9.5
14 otitis media 9.5
15 brain injury 9.5
16 encephalitis 9.5
17 hydrocephalus 9.5
18 transmitted_by 9.5
19 porencephaly 9.5
20 mastoiditis 9.5
21 osteomyelitis 9.5
22 endocarditis 9.5
23 mastitis 9.5
24 neuronitis 9.5
25 myocarditis 9.5

Graphical network of the top 20 diseases related to Neonatal Meningitis:



Diseases related to Neonatal Meningitis

Symptoms & Phenotypes for Neonatal Meningitis

Drugs & Therapeutics for Neonatal Meningitis

Drugs for Neonatal Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 124)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Gentamicins Phase 4,Phase 2,Phase 3
2 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1
3 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
4 Vaccines Phase 4,Phase 3,Phase 2
5 Neuromuscular Blocking Agents Phase 4
6
Progesterone Approved, Vet_approved Phase 3 57-83-0 5994
7
Meropenem Approved, Investigational Phase 3,Phase 1,Phase 2 119478-56-7 64778 441130
8
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
9
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
10
Cholecalciferol Approved, Nutraceutical Phase 2, Phase 3 67-97-0 6221 10883523 5280795
11
Ergocalciferol Approved, Nutraceutical Phase 2, Phase 3 50-14-6 5280793
12 vitamin d Phase 2, Phase 3
13 Progestins Phase 3
14
Lactitol Phase 3 585-86-4 3871
15 Thienamycins Phase 3,Phase 1,Phase 2
16 Heptavalent Pneumococcal Conjugate Vaccine Phase 3,Phase 2
17 Trace Elements Phase 3,Phase 2
18 Hormone Antagonists Phase 3
19 Hormones Phase 3
20 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
21 Pharmaceutical Solutions Phase 2, Phase 3
22 Ergocalciferols Phase 2, Phase 3
23 Estrogen Antagonists Phase 3
24 Vitamins Phase 3,Phase 2
25 Estrogens Phase 3
26 Immunoglobulins Phase 2, Phase 3
27 gamma-Globulins Phase 2, Phase 3
28 11-hydroxyprogesterone Phase 3
29 17-alpha-hydroxy-progesterone caproate Phase 3
30 Immunoglobulins, Intravenous Phase 2, Phase 3
31 Protective Agents Phase 3
32 Antibiotics, Antitubercular Phase 2, Phase 3
33 Retinol palmitate Phase 3
34 Rho(D) Immune Globulin Phase 2, Phase 3
35 Antibodies Phase 2, Phase 3
36 Micronutrients Phase 3,Phase 2
37 Bone Density Conservation Agents Phase 2, Phase 3
38 Antitubercular Agents Phase 2, Phase 3
39 Antioxidants Phase 3
40 retinol Nutraceutical Phase 3
41 Vitamin D2 Nutraceutical Phase 2, Phase 3
42 Calciferol Nutraceutical Phase 2, Phase 3
43 Caproate Nutraceutical Phase 3
44 Adjuvants, Immunologic Phase 2
45 BCG Vaccine Phase 2
46
Heparin Approved, Investigational 9005-49-6 772 46507594
47
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
48
Diazepam Approved, Illicit, Vet_approved 439-14-5 3016
49
Epinephrine Approved, Vet_approved 51-43-4 5816
50
Midazolam Approved, Illicit 59467-70-8 4192

Interventional clinical trials:

(show all 28)
id Name Status NCT ID Phase
1 Determination of Gentamicin Dosing in Neonatal Patients Unknown status NCT00198601 Phase 4
2 A Trial Comparing Two Pertussis-containing Vaccines in Pregnancy and Vaccine Responses in UK Mothers and Their Infants Active, not recruiting NCT02145624 Phase 4
3 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
4 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3
5 Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis Completed NCT02503761 Phase 3
6 Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis Completed NCT00707785 Phase 3
7 Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection Completed NCT01203345 Phase 2, Phase 3
8 A Study to Evaluate Safety and Immune Response of Novartis Meningococcal ACWY Vaccine In Infants Completed NCT00474526 Phase 3
9 Vitamin D Supplementation for Extremely Preterm Infants Completed NCT01600430 Phase 2, Phase 3
10 Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS) Completed NCT00099164 Phase 3
11 Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy Not yet recruiting NCT03008421 Phase 3
12 Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea Completed NCT00219401 Phase 2
13 Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age With Probable and Confirmed Meningitis Completed NCT01554124 Phase 1, Phase 2
14 Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination Completed NCT01650389 Phase 2
15 Clinical Outcome of Neonates With GBS Positive Culture-12 Year Retrospective Study Unknown status NCT00326313
16 Infection, Sepsis and Meningitis in Surinamese Neonates Completed NCT02486783
17 Early-Onset Sepsis Surveillance Study Completed NCT00874367
18 Membrane Sweeping in Group B Streptococcus (GBS) Positive Patients Completed NCT01180023
19 Group B Streptococcus: Attitudes to Immunisation in Pregnancy Completed NCT01982084
20 Early-Onset Sepsis an NICHD/CDC Surveillance Study Recruiting NCT02410486
21 Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality Recruiting NCT02600195
22 Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care Recruiting NCT01431326
23 Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS Meningitis Active, not recruiting NCT01719510
24 Integrative Approach to Identify Environmental Risk Factors for CC-17 Group B Streptococcal Neonatal Infection Active, not recruiting NCT02471937
25 Genetic Susceptibility and Biomarkers in Listeriosis (MONALISA-GENBIO) Enrolling by invitation NCT02924220
26 Breast Feeding Practice in High Risk Pregnant Women Not yet recruiting NCT03178916
27 Bovine Colostrum for Preterm Newborns Not yet recruiting NCT03085277
28 Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain Terminated NCT01606150

Search NIH Clinical Center for Neonatal Meningitis

Genetic Tests for Neonatal Meningitis

Anatomical Context for Neonatal Meningitis

MalaCards organs/tissues related to Neonatal Meningitis:

39
Brain, Breast

Publications for Neonatal Meningitis

Articles related to Neonatal Meningitis:

(show top 50) (show all 272)
id Title Authors Year
1
Complete Genome Sequence of the Neonatal Meningitis-Causing Escherichia coli Strain NMEC O18. ( 27811114 )
2016
2
Escherichia coli K1 Modulates Peroxisome Proliferator-Activated Receptor I^ and Glucose Transporter 1 at the Blood-Brain Barrier in Neonatal Meningitis. ( 27456707 )
2016
3
The Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881634 )
2016
4
Closing the Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881637 )
2016
5
Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. ( 27648334 )
2016
6
Neonatal meningitis and septicaemia caused by Salmonella agama. ( 26255922 )
2015
7
An Unusual Cause of Neonatal Meningitis. ( 25825073 )
2015
8
Complete Genome Sequence of Escherichia coli Strain RS218 (O18:H7:K1), Associated with Neonatal Meningitis. ( 26205862 )
2015
9
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis. ( 26407066 )
2015
10
Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC). ( 26467858 )
2015
11
Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis. ( 26449318 )
2015
12
Comparative study of bacteriological culture and real-time fluorescence quantitative PCR (RT-PCR) and multiplex PCR-based reverse line blot (mPCR/RLB) hybridization assay in the diagnosis of bacterial neonatal meningitis. ( 25200110 )
2014
13
Preterm delivery and neonatal meningitis due to transplacental acquisition of non-typhoidal Salmonella serovar montevideo. ( 24876215 )
2014
14
Neonatal Meningitis by Multidrug Resistant Elizabethkingia meningosepticum Identified by 16S Ribosomal RNA Gene Sequencing. ( 24678326 )
2014
15
Medical and neurosurgical management of Citrobacter koseri, a rare cause of neonatal meningitis. ( 24243285 )
2014
16
Neonatal Meningitis due to Neisseria meningitidis Serogroup Y. ( 25228622 )
2014
17
Sneathia species in a case of neonatal meningitis from Northeast India. ( 25988049 )
2014
18
Neonatal meningitis complicating with pneumocephalus. ( 24741257 )
2014
19
Angiotensin II Receptor Type 1--A Novel Target for Preventing Neonatal Meningitis in Mice by Escherichia coli K1. ( 24041786 )
2014
20
The ssbL gene harbored by the ColV plasmid of an Escherichia coli neonatal meningitis strain is an auxiliary virulence factor boosting the production of siderophores through the shikimate pathway. ( 24443535 )
2014
21
Successful off-label use of the Cepheid Xpert GBS in a late-onset neonatal meningitis by Streptococcus agalactiae. ( 25197396 )
2014
22
Neonatal meningitis: risk factors, causes, and neurologic complications. ( 25657770 )
2014
23
Neonatal meningitis associated with osteomyelitis and epidural empyema. ( 23975909 )
2013
24
Neonatal meningitis due to Morganella morganii. ( 22267858 )
2013
25
A Case of Myocarditis Following Neonatal Meningitis Caused by Coxsackievirus B1 in Spite of Intravenous Immunoglobulin Treatment. ( 24122863 )
2013
26
Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae. ( 22683802 )
2013
27
Dexamethasone for management of neonatal meningitis. ( 23355014 )
2013
28
Cronobacter sakazakii ST4 strains and neonatal meningitis, United States. ( 23260316 )
2013
29
Neonatal Meningitis and Sepsis by Chryseobacterium indologenes: A Rare and Resistant Bacterium. ( 23681831 )
2013
30
Cronobacter: an emerging opportunistic pathogen associated with neonatal meningitis, sepsis and necrotizing enterocolitis. ( 23538645 )
2013
31
'Leptotrichia amnionii', a newly reported cause of early onset neonatal meningitis. ( 23378562 )
2013
32
Role of dexamethasone in neonatal meningitis: a randomized controlled trial. ( 23054852 )
2013
33
Neonatal meningitis: a diagnostic dilemma. ( 23155921 )
2012
34
Neonatal meningitis and the developing world. ( 22035279 )
2012
35
Genotypic and phenotypic traits that distinguish neonatal meningitis-associated Escherichia coli from fecal E. coli isolates of healthy human hosts. ( 22706051 )
2012
36
Neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. ( 22002578 )
2012
37
An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius. ( 22169781 )
2011
38
Enrichment culture of CSF is of limited value in the diagnosis of neonatal meningitis. ( 21267620 )
2011
39
Systematic review: neonatal meningitis in the developing world. ( 21395927 )
2011
40
Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10. ( 22123760 )
2011
41
Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. ( 21186256 )
2011
42
Neonatal meningitis: can we do better? ( 22125031 )
2011
43
Neonatal meningitis caused by Elizabethkingia meningoseptica in Saudi Arabia. ( 21997946 )
2011
44
Neonatal meningitis according to the microbiological diagnosis: a decade of experience in a tertiary center. ( 21243246 )
2010
45
Avian-pathogenic Escherichia coli strains are similar to neonatal meningitis E. coli strains and are able to cause meningitis in the rat model of human disease. ( 20515929 )
2010
46
Escherichia coli K1 promotes the ligation of CD47 with thrombospondin-1 to prevent the maturation of dendritic cells in the pathogenesis of neonatal meningitis. ( 20675593 )
2010
47
Inhibition of inducible nitric oxide controls pathogen load and brain damage by enhancing phagocytosis of Escherichia coli K1 in neonatal meningitis. ( 20093483 )
2010
48
Ureaplasma: pathogen or passenger in neonatal meningitis? ( 19910840 )
2010
49
Correlation between behavioral deficits and decreased brain-derived neurotrophic [correction of neurotrofic] factor in neonatal meningitis. ( 20452683 )
2010
50
Relative penicillin resistance in Streptococcus bovis. A case of neonatal meningitis. ( 19712186 )
2009

Variations for Neonatal Meningitis

Expression for Neonatal Meningitis

Search GEO for disease gene expression data for Neonatal Meningitis.

Pathways for Neonatal Meningitis

Pathways related to Neonatal Meningitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.55 PPARG SLC2A1
2 11.09 PPARG SLC2A1

GO Terms for Neonatal Meningitis

Molecular functions related to Neonatal Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 PPARG SLC2A1

Sources for Neonatal Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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