MCID: NNT021
MIFTS: 27

Neonatal Meningitis

Categories: Rare diseases

Aliases & Classifications for Neonatal Meningitis

MalaCards integrated aliases for Neonatal Meningitis:

Name: Neonatal Meningitis 50 69
Meningitis, Neonatal 50

Classifications:



Summaries for Neonatal Meningitis

MalaCards based summary : Neonatal Meningitis, also known as meningitis, neonatal, is related to meningitis and influenza. An important gene associated with Neonatal Meningitis is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways are Pathways in cancer and Glucose / Energy Metabolism. The drugs Anti-Bacterial Agents and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include brain, breast and colon.

Wikipedia : 72 Neonatal meningitis is a serious medical condition in infants. Meningitis is an inflammation of the... more...

Related Diseases for Neonatal Meningitis

Diseases related to Neonatal Meningitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
id Related Disease Score Top Affiliating Genes
1 meningitis 10.7
2 influenza 9.7
3 arachnoiditis 9.6
4 acute cystitis 9.6
5 cystitis 9.6
6 cerebritis 9.6
7 haemophilus influenzae 9.6
8 bacteremia 9.5
9 otitis media 9.5
10 brain injury 9.5
11 hydrocephalus 9.5
12 porencephaly 9.5
13 mastoiditis 9.5
14 osteomyelitis 9.5
15 endocarditis 9.5
16 mastitis 9.5
17 neuronitis 9.5
18 myocarditis 9.5
19 diabetes insipidus 9.5
20 encephalitis 9.5
21 transmitted_by 9.5
22 peritoneal mesothelioma 9.4 PPARG SLC2A1
23 non-distal trisomy 10q 9.3 PPARG SLC2A1
24 peroneal neuropathy 9.1 PPARG SLC2A1
25 nephronophthisis familial adult spastic quadriparesis 8.9 CD47 PPARG SLC2A1

Graphical network of the top 20 diseases related to Neonatal Meningitis:



Diseases related to Neonatal Meningitis

Symptoms & Phenotypes for Neonatal Meningitis

Drugs & Therapeutics for Neonatal Meningitis

Drugs for Neonatal Meningitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3,Phase 1
2 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
3 Gentamicins Phase 4,Phase 2,Phase 3
4 Vaccines Phase 4,Phase 2
5 Neuromuscular Blocking Agents Phase 4
6
Ampicillin Approved, Vet_approved Phase 2, Phase 3 69-53-4 6249
7
Meropenem Approved, Investigational Phase 3,Phase 1,Phase 2 119478-56-7 64778 441130
8
Vitamin A Approved, Nutraceutical, Vet_approved Phase 3 11103-57-4, 68-26-8 445354
9 Antibiotics, Antitubercular Phase 2, Phase 3
10 Antitubercular Agents Phase 2, Phase 3
11 Thienamycins Phase 3,Phase 1,Phase 2
12 Antioxidants Phase 3
13 Micronutrients Phase 3
14 Protective Agents Phase 3
15 Retinol palmitate Phase 3
16 Trace Elements Phase 3
17 Vitamins Phase 3
18 Antibodies Phase 2, Phase 3
19 gamma-Globulins Phase 2, Phase 3
20 Immunoglobulins Phase 2, Phase 3
21 Immunoglobulins, Intravenous Phase 2, Phase 3
22 Pharmaceutical Solutions Phase 2, Phase 3
23 Rho(D) Immune Globulin Phase 2, Phase 3
24 retinol Nutraceutical Phase 3
25
BCG vaccine Investigational Phase 2
26 Heptavalent Pneumococcal Conjugate Vaccine Phase 2
27 Adjuvants, Immunologic Phase 2
28
Lidocaine Approved, Vet_approved 137-58-6 3676
29 Anesthetics
30 Anesthetics, Local
31 Anti-Arrhythmia Agents
32 Central Nervous System Depressants
33 Diuretics, Potassium Sparing
34 Peripheral Nervous System Agents
35 Sodium Channel Blockers

Interventional clinical trials:

(show all 23)

id Name Status NCT ID Phase Drugs
1 Determination of Gentamicin Dosing in Neonatal Patients Unknown status NCT00198601 Phase 4 Gentamicin in Uniject Pre-filled syringe
2 A Trial Comparing Two Pertussis-containing Vaccines in Pregnancy and Vaccine Responses in UK Mothers and Their Infants Active, not recruiting NCT02145624 Phase 4 Repevax;Boostrix-IPV
3 IHPOTOTAM : Induced HyPOthermia TO Treat Adult Meningitis Terminated NCT00774631 Phase 4
4 Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Completed NCT01633294 Phase 2, Phase 3 Ampicillin + gentamicin
5 Bolus Versus Prolonged Infusion of Meropenem in Newborn With Late Onset Sepsis Completed NCT02503761 Phase 3 Meropenem.
6 Effect of Vitamin A in the Treatment of Neonatal Sepsis and Necrotizing Enterocolitis Completed NCT00707785 Phase 3
7 Intravenous Immune Globulin (IVIG) to Prevent Neonatal Infection Completed NCT01203345 Phase 2, Phase 3 IVIG;Placebo
8 7 Days Versus 14 Days of Antibiotics for Neonatal Sepsis Not yet recruiting NCT03280147 Phase 3 7-day course of antibiotics;14-day course of antibiotics
9 Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy Not yet recruiting NCT03008421 Phase 3
10 Neonatal Immunization With Pneumococcal Conjugate Vaccine in Papua New Guinea Completed NCT00219401 Phase 2
11 Pharmacokinetics and Safety of Meropenem in Infants Below 90 Days of Age With Probable and Confirmed Meningitis Completed NCT01554124 Phase 1, Phase 2 Meropenem
12 Safety and Immunogenicity of MVA85A Prime and Bacille Calmette-Guerin Boost Vaccination Completed NCT01650389 Phase 2
13 Clinical Outcome of Neonates With GBS Positive Culture-12 Year Retrospective Study Unknown status NCT00326313
14 Infection, Sepsis and Meningitis in Surinamese Neonates Completed NCT02486783
15 Early-Onset Sepsis Surveillance Study Completed NCT00874367
16 Membrane Sweeping in Group B Streptococcus (GBS) Positive Patients Completed NCT01180023
17 Group B Streptococcus: Attitudes to Immunisation in Pregnancy Completed NCT01982084
18 Early-Onset Sepsis an NICHD/CDC Surveillance Study Recruiting NCT02410486
19 Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality Recruiting NCT02600195
20 Breast Feeding Practice in High Risk Pregnant Women Recruiting NCT03178916
21 Interest of the Detection of Hyper-virulent Clone ST17 of Group B Strep (GBS) for the Prevention of Neonatal GBS Meningitis Active, not recruiting NCT01719510
22 Integrative Approach to Identify Environmental Risk Factors for CC-17 Group B Streptococcal Neonatal Infection Active, not recruiting NCT02471937
23 Lumbar Punctures in Neonates: Improving Success Rates and Minimizing Pain Terminated NCT01606150 1% lidocaine;topical lidocaine

Search NIH Clinical Center for Neonatal Meningitis

Genetic Tests for Neonatal Meningitis

Anatomical Context for Neonatal Meningitis

MalaCards organs/tissues related to Neonatal Meningitis:

39
Brain, Breast, Colon

Publications for Neonatal Meningitis

Articles related to Neonatal Meningitis:

(show top 50) (show all 276)
id Title Authors Year
1
Neonatal Meningitis: Overcoming Challenges in Diagnosis, Prognosis, and Treatment with Omics. ( 28670576 )
2017
2
Bacterial aetiology of neonatal meningitis: A study from north-east India. ( 28574028 )
2017
3
Neonatal cranial sonography: ultrasound findings in neonatal meningitis-a pictorial review. ( 28275563 )
2017
4
The Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881634 )
2016
5
Empedobacter brevis Meningitis in a Neonate: A Very Rare Case of Neonatal Meningitis and Literature Review. ( 27648334 )
2016
6
Escherichia coli K1 Modulates Peroxisome Proliferator-Activated Receptor I^ and Glucose Transporter 1 at the Blood-Brain Barrier in Neonatal Meningitis. ( 27456707 )
2016
7
Complete Genome Sequence of the Neonatal Meningitis-Causing Escherichia coli Strain NMEC O18. ( 27811114 )
2016
8
Neuroimaging Complication of Neonatal Meningitis in Full-Term and Near-Term Newborns: A Retrospective Study of One Center. ( 28229093 )
2016
9
Closing the Brief Case: Neonatal Meningitis Caused by Listeria monocytogenes Diagnosed by Multiplex Molecular Panel. ( 27881637 )
2016
10
Neonatal meningitis and septicaemia caused by Salmonella agama. ( 26255922 )
2015
11
Characterizing the pathotype of neonatal meningitis causing Escherichia coli (NMEC). ( 26467858 )
2015
12
An Unusual Cause of Neonatal Meningitis. ( 25825073 )
2015
13
Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis. ( 26449318 )
2015
14
Serotype O18 avian pathogenic and neonatal meningitis Escherichia coli strains employ similar pathogenic strategies for the onset of meningitis. ( 26407066 )
2015
15
Complete Genome Sequence of Escherichia coli Strain RS218 (O18:H7:K1), Associated with Neonatal Meningitis. ( 26205862 )
2015
16
Preterm delivery and neonatal meningitis due to transplacental acquisition of non-typhoidal Salmonella serovar montevideo. ( 24876215 )
2014
17
Successful off-label use of the Cepheid Xpert GBS in a late-onset neonatal meningitis by Streptococcus agalactiae. ( 25197396 )
2014
18
Sneathia species in a case of neonatal meningitis from Northeast India. ( 25988049 )
2014
19
Comparative study of bacteriological culture and real-time fluorescence quantitative PCR (RT-PCR) and multiplex PCR-based reverse line blot (mPCR/RLB) hybridization assay in the diagnosis of bacterial neonatal meningitis. ( 25200110 )
2014
20
Neonatal meningitis complicating with pneumocephalus. ( 24741257 )
2014
21
Angiotensin II Receptor Type 1--A Novel Target for Preventing Neonatal Meningitis in Mice by Escherichia coli K1. ( 24041786 )
2014
22
Medical and neurosurgical management of Citrobacter koseri, a rare cause of neonatal meningitis. ( 24243285 )
2014
23
Neonatal meningitis: risk factors, causes, and neurologic complications. ( 25657770 )
2014
24
The ssbL gene harbored by the ColV plasmid of an Escherichia coli neonatal meningitis strain is an auxiliary virulence factor boosting the production of siderophores through the shikimate pathway. ( 24443535 )
2014
25
Neonatal Meningitis due to Neisseria meningitidis Serogroup Y. ( 25228622 )
2014
26
Neonatal Meningitis by Multidrug Resistant Elizabethkingia meningosepticum Identified by 16S Ribosomal RNA Gene Sequencing. ( 24678326 )
2014
27
Neonatal Meningitis and Sepsis by Chryseobacterium indologenes: A Rare and Resistant Bacterium. ( 23681831 )
2013
28
Neonatal meningitis associated with osteomyelitis and epidural empyema. ( 23975909 )
2013
29
Cronobacter: an emerging opportunistic pathogen associated with neonatal meningitis, sepsis and necrotizing enterocolitis. ( 23538645 )
2013
30
Evaluation of the brain-derived neurotrophic factor, nerve growth factor and memory in adult rats survivors of the neonatal meningitis by Streptococcus agalactiae. ( 22683802 )
2013
31
'Leptotrichia amnionii', a newly reported cause of early onset neonatal meningitis. ( 23378562 )
2013
32
Dexamethasone for management of neonatal meningitis. ( 23355014 )
2013
33
A Case of Myocarditis Following Neonatal Meningitis Caused by Coxsackievirus B1 in Spite of Intravenous Immunoglobulin Treatment. ( 24122863 )
2013
34
Neonatal meningitis due to Morganella morganii. ( 22267858 )
2013
35
Role of dexamethasone in neonatal meningitis: a randomized controlled trial. ( 23054852 )
2013
36
Cronobacter sakazakii ST4 strains and neonatal meningitis, United States. ( 23260316 )
2013
37
Neonatal meningitis and the developing world. ( 22035279 )
2012
38
Neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. ( 22002578 )
2012
39
Neonatal meningitis: a diagnostic dilemma. ( 23155921 )
2012
40
Genotypic and phenotypic traits that distinguish neonatal meningitis-associated Escherichia coli from fecal E. coli isolates of healthy human hosts. ( 22706051 )
2012
41
Neonatal meningitis caused by Elizabethkingia meningoseptica in Saudi Arabia. ( 21997946 )
2011
42
Enrichment culture of CSF is of limited value in the diagnosis of neonatal meningitis. ( 21267620 )
2011
43
Neonatal meningitis: can we do better? ( 22125031 )
2011
44
An outbreak of Elizabethkingia meningoseptica neonatal meningitis in Mauritius. ( 22169781 )
2011
45
Bacterial pore-forming cytolysins induce neuronal damage in a rat model of neonatal meningitis. ( 21186256 )
2011
46
Systematic review: neonatal meningitis in the developing world. ( 21395927 )
2011
47
Complete genome sequence of the neonatal-meningitis-associated Escherichia coli strain CE10. ( 22123760 )
2011
48
Ureaplasma: pathogen or passenger in neonatal meningitis? ( 19910840 )
2010
49
Inhibition of inducible nitric oxide controls pathogen load and brain damage by enhancing phagocytosis of Escherichia coli K1 in neonatal meningitis. ( 20093483 )
2010
50
Correlation between behavioral deficits and decreased brain-derived neurotrophic [correction of neurotrofic] factor in neonatal meningitis. ( 20452683 )
2010

Variations for Neonatal Meningitis

Expression for Neonatal Meningitis

Search GEO for disease gene expression data for Neonatal Meningitis.

Pathways for Neonatal Meningitis

Pathways related to Neonatal Meningitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.55 PPARG SLC2A1
2 11.09 PPARG SLC2A1

GO Terms for Neonatal Meningitis

Molecular functions related to Neonatal Meningitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein self-association GO:0043621 8.62 PPARG SLC2A1

Sources for Neonatal Meningitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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