MCID: NNT006
MIFTS: 24

Neonatal Myasthenia Gravis malady

Categories: Immune diseases, Neuronal diseases, Fetal diseases, Bone diseases, Rare diseases

Aliases & Classifications for Neonatal Myasthenia Gravis

Aliases & Descriptions for Neonatal Myasthenia Gravis:

Name: Neonatal Myasthenia Gravis 12 14
Myasthenia Gravis, Neonatal 42

Classifications:



External Ids:

Disease Ontology 12 DOID:14043
ICD9CM 35 775.2
MeSH 42 D020941
SNOMED-CT 64 82178003
UMLS 69 C0158982

Summaries for Neonatal Myasthenia Gravis

MalaCards based summary : Neonatal Myasthenia Gravis, also known as myasthenia gravis, neonatal, is related to transient neonatal myasthenia gravis and myasthenia gravis. An important gene associated with Neonatal Myasthenia Gravis is CHRNG (Cholinergic Receptor Nicotinic Gamma Subunit). The drug Cyclophosphamide has been mentioned in the context of this disorder. Affiliated tissues include testes, and related phenotypes are Increased shRNA abundance and mortality/aging

Related Diseases for Neonatal Myasthenia Gravis

Graphical network of the top 20 diseases related to Neonatal Myasthenia Gravis:



Diseases related to Neonatal Myasthenia Gravis

Symptoms & Phenotypes for Neonatal Myasthenia Gravis

GenomeRNAi Phenotypes related to Neonatal Myasthenia Gravis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance GR00327-A 8.8 AFP AQP4 SERPINH1

MGI Mouse Phenotypes related to Neonatal Myasthenia Gravis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.5 CHRNG DPAGT1 MB MUSK SERPINH1 AFP
2 respiratory system MP:0005388 9.02 AQP4 CHRNG MB MUSK SERPINH1

Drugs & Therapeutics for Neonatal Myasthenia Gravis

Drugs for Neonatal Myasthenia Gravis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclophosphamide Approved, Investigational Phase 1 50-18-0, 6055-19-2 2907

Interventional clinical trials:


id Name Status NCT ID Phase
1 Hematopoietic Stem Cell Therapy for Patients With Refractory Myasthenia Gravis Terminated NCT00424489 Phase 1
2 Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford Recruiting NCT01793168

Search NIH Clinical Center for Neonatal Myasthenia Gravis

Cochrane evidence based reviews: myasthenia gravis, neonatal

Genetic Tests for Neonatal Myasthenia Gravis

Anatomical Context for Neonatal Myasthenia Gravis

MalaCards organs/tissues related to Neonatal Myasthenia Gravis:

39
Testes

Publications for Neonatal Myasthenia Gravis

Articles related to Neonatal Myasthenia Gravis:

(show all 46)
id Title Authors Year
1
Transient neonatal myasthenia gravis due to a mother with ocular onset of anti-muscle specific kinase myasthenia gravis. ( 28495046 )
2017
2
50 Years Ago in TheJournal ofPediatrics: Neonatal Myasthenia Gravis. ( 27017463 )
2016
3
Seronegative Maternal Ocular Myasthenia Gravis and Delayed Transient Neonatal Myasthenia Gravis. ( 26989568 )
2016
4
Prenatal immunomodulation treatment in neonatal myasthenia gravis. ( 23982940 )
2013
5
Transient neonatal myasthenia gravis revealing a myasthenia gravis and a systemic lupus erythematosus in the mother: case report and review of the literature. ( 19488958 )
2010
6
Transient neonatal myasthenia gravis in a baby born to a mother with new-onset anti-MuSK-mediated myasthenia gravis. ( 19955986 )
2009
7
Isolated facial and bulbar paresis: a persistent manifestation of neonatal myasthenia gravis. ( 18195270 )
2008
8
Can neonatal myasthenia gravis be predicted? ( 18681836 )
2008
9
Seronegative neonatal myasthenia gravis in one of the twins. ( 15475637 )
2004
10
Intravenous immunoglobulin in neonatal myasthenia gravis. ( 10586190 )
1999
11
Failure of intravenously administered immunoglobulin in the treatment of neonatal myasthenia gravis. ( 9931536 )
1999
12
High-dose intravenous immunoglobulin in transient neonatal myasthenia gravis. ( 9535308 )
1998
13
Transient neonatal myasthenia gravis and pyloric stenosis. ( 8534471 )
1995
14
Neonatal myasthenia gravis and the role of agalactosyl IgG. ( 8679902 )
1995
15
Association of neonatal myasthenia gravis with antibodies against the fetal acetylcholine receptor. ( 8040310 )
1994
16
The role of intrapartum vibroacoustic stimulation in the prediction of neonatal myasthenia gravis. ( 8022331 )
1994
17
Transient neonatal myasthenia gravis. ( 1573230 )
1992
18
Presence of anti-acetylcholine receptor antibodies in human milk: possible correlation with neonatal myasthenia gravis. ( 1391599 )
1992
19
Anti-acetylcholine receptor antibodies in neonatal myasthenia gravis: heterogeneity and pathogenic significance. ( 1883479 )
1991
20
Neonatal myasthenia gravis: antigenic specificities of antibodies in sera from mothers and their infants. ( 1695559 )
1990
21
Alpha-bungarotoxin blocking antibodies in neonatal myasthenia gravis: frequency and selectivity. ( 2908881 )
1989
22
Neonatal myasthenia gravis: a new clinical and immunologic appraisal on 30 cases. ( 3336445 )
1988
23
Neonatal myasthenia gravis: specific advantages of repetitive stimulation over edrophonium testing. ( 3242526 )
1988
24
Neonatal myasthenia gravis: clinical and immunological study of seven mothers and their newborn infants. ( 3734055 )
1986
25
Neonatal myasthenia gravis. Anti-acetylcholine receptor antibodies in the amniotic fluid. ( 6746895 )
1984
26
Neonatal myasthenia gravis in the infant of an asymptomatic thymectomized mother. ( 7104893 )
1982
27
Neonatal myasthenia gravis. ( 7211772 )
1981
28
Exchange transfusion in neonatal myasthenia gravis. ( 7195520 )
1981
29
Antiacetylcholine receptor antibody in neonatal myasthenia gravis. ( 6163352 )
1981
30
Acetylcholine receptor antibodies in absence of neonatal myasthenia gravis. ( 7436824 )
1980
31
Significance in neonatal myasthenia gravis of inhibitory effect of amniotic fluid on binding of antibodies to acetylcholine receptor. ( 92675 )
1979
32
Respiratory studies in an infant with neonatal myasthenia gravis. ( 464928 )
1979
33
Neonatal myasthenia gravis in the infant of a myasthenic mother in remission. ( 574370 )
1979
34
Prolonged neonatal myasthenia gravis: electrophysiological studies. ( 727721 )
1978
35
Nursing care study: transient neonatal myasthenia gravis. ( 250054 )
1978
36
The role of anti-acetylcholine receptor antibody in neonatal myasthenia gravis. ( 757366 )
1978
37
Anti-acetylcholine receptor IgG in neonatal myasthenia gravis. ( 865592 )
1977
38
Time course of neonatal myasthenia gravis and unsuspectedly long duration of neuromuscular block in distal muscles. ( 190536 )
1977
39
Anti-acetylcholine receptor antibody in neonatal myasthenia gravis. ( 830279 )
1977
40
Monitoring muscle weakness in neonatal myasthenia gravis. ( 1203704 )
1975
41
Letter: Neonatal myasthenia gravis. ( 4448549 )
1974
42
Neonatal myasthenia gravis and antimuscle antibodies. ( 4926622 )
1971
43
Neonatal myasthenia gravis: report of two cases and review of the literature. ( 5309787 )
1970
44
Neonatal myasthenia gravis. ( 4179873 )
1969
45
Pregnancy in myasthenia gravis and neonatal myasthenia gravis. ( 13268469 )
1955
46
Neonatal myasthenia gravis; report of a case. ( 13009187 )
1953

Variations for Neonatal Myasthenia Gravis

Expression for Neonatal Myasthenia Gravis

Search GEO for disease gene expression data for Neonatal Myasthenia Gravis.

Pathways for Neonatal Myasthenia Gravis

GO Terms for Neonatal Myasthenia Gravis

Sources for Neonatal Myasthenia Gravis

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59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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