MCID: NNT006
MIFTS: 24

Neonatal Myasthenia Gravis malady

Categories: Immune diseases, Neuronal diseases, Fetal diseases, Bone diseases, Rare diseases

Aliases & Classifications for Neonatal Myasthenia Gravis

About this section

Aliases & Descriptions for Neonatal Myasthenia Gravis:

Name: Neonatal Myasthenia Gravis 11 13
 
Myasthenia Gravis, Neonatal 39

Classifications:



External Ids:

Disease Ontology11 DOID:14043
ICD9CM32 775.2
SNOMED-CT62 82178003
MeSH39 D020941

Summaries for Neonatal Myasthenia Gravis

About this section
MalaCards based summary: Neonatal Myasthenia Gravis, also known as myasthenia gravis, neonatal, is related to transient neonatal myasthenia gravis and myasthenia gravis. An important gene associated with Neonatal Myasthenia Gravis is CHRNG (Cholinergic Receptor Nicotinic Gamma Subunit). Affiliated tissues include testes, and related mouse phenotypes are Increased shRNA abundance and respiratory system.

Related Diseases for Neonatal Myasthenia Gravis

About this section

Graphical network of diseases related to Neonatal Myasthenia Gravis:



Diseases related to neonatal myasthenia gravis

Symptoms & Phenotypes for Neonatal Myasthenia Gravis

About this section

GenomeRNAi Phenotypes related to Neonatal Myasthenia Gravis according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00327-A9.3AFP, AQP4, SERPINH1

MGI Mouse Phenotypes related to Neonatal Myasthenia Gravis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.0AQP4, CHRNG, MB, MUSK, SERPINH1
2MP:00107687.6AFP, AQP4, CHRNG, DPAGT1, MB, MUSK

Drugs & Therapeutics for Neonatal Myasthenia Gravis

About this section

Drugs for Neonatal Myasthenia Gravis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Cyclophosphamideapproved, investigationalPhase 1293550-18-0, 6055-19-22907
Synonyms:
(+-)-Cyclophosphamide
(-)-Cyclophosphamide
(RS)-Cyclophosphamide
1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine
1-Bis(2-chloroethyl)amino-1-oxo-2-aza-5-oxaphosphoridin
2-[Bis(2-chloroethylamino)]-tetrahydro-2H-1,3,2-oxazaphosphorine-2-oxide
4-Hydroxy-cyclophosphan-mamophosphatide
50-18-0
60007-95-6
6055-19-2 (monohydrate)
75526-90-8
AC1L1EQQ
AI3-26198
ASTA
ASTA B518
Anhydrous cyclophosphamide
Asta B 518
B 518
B-518
BRN 0011744
BSPBio_002099
Bis(2-chloroethyl)phosphoramide cyclic propanolamide ester
C 0768
C07888
C7H15Cl2N2O2P
CB 4564
CB-4564
CCRIS 188
CHEBI:4027
CHEMBL32520
CHEMBL88
CID2907
CP
CPA
CTX
CY
Ciclofosfamida
Ciclofosfamida [INN-Spanish]
Ciclofosfamide
Ciclophosphamide
Ciclophosphamide [INN]
Clafen
Claphene
Cycloblastin
Cyclophosphamid
Cyclophosphamide
Cyclophosphamide (INN)
Cyclophosphamide (TN)
Cyclophosphamide (anhydrous form)
Cyclophosphamide (anhydrous)
Cyclophosphamide Monohydrate
Cyclophosphamide Sterile
Cyclophosphamide anhydrous
Cyclophosphamide, (+-)-Isomer
Cyclophosphamides
Cyclophosphamidum
Cyclophosphamidum [INN-Latin]
Cyclophosphan
Cyclophosphane
Cyclophosphanum
Cyclophosphoramide
Cyclostin
Cyklofosfamid
Cyklofosfamid [Czech]
Cytophosphan
Cytophosphane
Cytoxan
Cytoxan (TN)
Cytoxan Lyoph
D,L-Cyclophosphamide
D07760
 
DB00531
DivK1c_000246
EINECS 200-015-4
EU-0100238
Endoxan
Endoxan R
Endoxan-Asta
Endoxana
Endoxanal
Endoxane
Enduxan
Genoxal
HMS2090A12
HSDB 3047
Hexadrin
IDI1_000246
KBio1_000246
KBio2_001338
KBio2_003906
KBio2_006474
KBio3_001319
KBioGR_000888
KBioSS_001338
LS-1302
LS-99787
Ledoxina
Lopac-C-0768
Lopac0_000238
Lyophilized Cytoxan
Mitoxan
MolPort-001-783-420
N,N-Bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amine 2-oxide
N,N-Bis(2-chloroethyl)tetrahydro-2H-1,3,2-oxazaphosphorin-2-amine 2-oxide
NCGC00015209-01
NCGC00015209-03
NCGC00015209-06
NCGC00091741-02
NCGC00091741-03
NCI-C04900
NCI60_002097
NINDS_000246
NSC 26271
NSC-26271
NSC26271
NSC273033
NSC273034
Neosar
Occupation, cyclophosphamide exposure
Procytox
RCRA waste no. U058
Rcra Waste Number U058
Rcra waste number U058
Revimmune
S1217_Selleck
SK 20501
SPBio_001071
STK177249
STOCK2S-91217
Semdoxan
Sendoxan
Senduxan
Spectrum2_001146
Spectrum3_000370
Spectrum4_000304
Spectrum5_000795
Spectrum_000858
UNII-6UXW23996M
WLN: T6MPOTJ BO BN2G2G
Zyklophosphamid
Zyklophosphamid [German]
bis(2-Chloroethyl)phosphami de cyclic propanolamide
bis(2-Chloroethyl)phosphamide cyclic propanolamide ester
cyclophosphamide

Interventional clinical trials:

idNameStatusNCT IDPhase
1Hematopoietic Stem Cell Therapy for Patients With Refractory Myasthenia GravisTerminatedNCT00424489Phase 1
2Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT01793168

Search NIH Clinical Center for Neonatal Myasthenia Gravis


Cochrane evidence based reviews: myasthenia gravis, neonatal

Genetic Tests for Neonatal Myasthenia Gravis

About this section

Anatomical Context for Neonatal Myasthenia Gravis

About this section

MalaCards organs/tissues related to Neonatal Myasthenia Gravis:

36
Testes

Publications for Neonatal Myasthenia Gravis

About this section

Articles related to Neonatal Myasthenia Gravis:

(show all 46)
idTitleAuthorsYear
1
Transient neonatal myasthenia gravis due to a mother with ocular onset of anti-muscle specific kinase myasthenia gravis. (28495046)
2017
2
50 Years Ago in TheJournal ofPediatrics: Neonatal Myasthenia Gravis. (27017463)
2016
3
Seronegative Maternal Ocular Myasthenia Gravis and Delayed Transient Neonatal Myasthenia Gravis. (26989568)
2016
4
Prenatal immunomodulation treatment in neonatal myasthenia gravis. (23982940)
2013
5
Transient neonatal myasthenia gravis revealing a myasthenia gravis and a systemic lupus erythematosus in the mother: case report and review of the literature. (19488958)
2010
6
Transient neonatal myasthenia gravis in a baby born to a mother with new-onset anti-MuSK-mediated myasthenia gravis. (19955986)
2009
7
Isolated facial and bulbar paresis: a persistent manifestation of neonatal myasthenia gravis. (18195270)
2008
8
Can neonatal myasthenia gravis be predicted? (18681836)
2008
9
Seronegative neonatal myasthenia gravis in one of the twins. (15475637)
2004
10
Intravenous immunoglobulin in neonatal myasthenia gravis. (10586190)
1999
11
Failure of intravenously administered immunoglobulin in the treatment of neonatal myasthenia gravis. (9931536)
1999
12
High-dose intravenous immunoglobulin in transient neonatal myasthenia gravis. (9535308)
1998
13
Transient neonatal myasthenia gravis and pyloric stenosis. (8534471)
1995
14
Neonatal myasthenia gravis and the role of agalactosyl IgG. (8679902)
1995
15
Association of neonatal myasthenia gravis with antibodies against the fetal acetylcholine receptor. (8040310)
1994
16
The role of intrapartum vibroacoustic stimulation in the prediction of neonatal myasthenia gravis. (8022331)
1994
17
Transient neonatal myasthenia gravis. (1573230)
1992
18
Presence of anti-acetylcholine receptor antibodies in human milk: possible correlation with neonatal myasthenia gravis. (1391599)
1992
19
Anti-acetylcholine receptor antibodies in neonatal myasthenia gravis: heterogeneity and pathogenic significance. (1883479)
1991
20
Neonatal myasthenia gravis: antigenic specificities of antibodies in sera from mothers and their infants. (1695559)
1990
21
Alpha-bungarotoxin blocking antibodies in neonatal myasthenia gravis: frequency and selectivity. (2908881)
1989
22
Neonatal myasthenia gravis: a new clinical and immunologic appraisal on 30 cases. (3336445)
1988
23
Neonatal myasthenia gravis: specific advantages of repetitive stimulation over edrophonium testing. (3242526)
1988
24
Neonatal myasthenia gravis: clinical and immunological study of seven mothers and their newborn infants. (3734055)
1986
25
Neonatal myasthenia gravis. Anti-acetylcholine receptor antibodies in the amniotic fluid. (6746895)
1984
26
Neonatal myasthenia gravis in the infant of an asymptomatic thymectomized mother. (7104893)
1982
27
Neonatal myasthenia gravis. (7211772)
1981
28
Exchange transfusion in neonatal myasthenia gravis. (7195520)
1981
29
Antiacetylcholine receptor antibody in neonatal myasthenia gravis. (6163352)
1981
30
Acetylcholine receptor antibodies in absence of neonatal myasthenia gravis. (7436824)
1980
31
Significance in neonatal myasthenia gravis of inhibitory effect of amniotic fluid on binding of antibodies to acetylcholine receptor. (92675)
1979
32
Respiratory studies in an infant with neonatal myasthenia gravis. (464928)
1979
33
Neonatal myasthenia gravis in the infant of a myasthenic mother in remission. (574370)
1979
34
Prolonged neonatal myasthenia gravis: electrophysiological studies. (727721)
1978
35
Nursing care study: transient neonatal myasthenia gravis. (250054)
1978
36
The role of anti-acetylcholine receptor antibody in neonatal myasthenia gravis. (757366)
1978
37
Anti-acetylcholine receptor IgG in neonatal myasthenia gravis. (865592)
1977
38
Time course of neonatal myasthenia gravis and unsuspectedly long duration of neuromuscular block in distal muscles. (190536)
1977
39
Anti-acetylcholine receptor antibody in neonatal myasthenia gravis. (830279)
1977
40
Monitoring muscle weakness in neonatal myasthenia gravis. (1203704)
1975
41
Letter: Neonatal myasthenia gravis. (4448549)
1974
42
Neonatal myasthenia gravis and antimuscle antibodies. (4926622)
1971
43
Neonatal myasthenia gravis: report of two cases and review of the literature. (5309787)
1970
44
Neonatal myasthenia gravis. (4179873)
1969
45
Pregnancy in myasthenia gravis and neonatal myasthenia gravis. (13268469)
1955
46
Neonatal myasthenia gravis; report of a case. (13009187)
1953

Variations for Neonatal Myasthenia Gravis

About this section

Expression for genes affiliated with Neonatal Myasthenia Gravis

About this section
Search GEO for disease gene expression data for Neonatal Myasthenia Gravis.

Pathways for genes affiliated with Neonatal Myasthenia Gravis

About this section

GO Terms for genes affiliated with Neonatal Myasthenia Gravis

About this section

Sources for Neonatal Myasthenia Gravis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet