MCID: NNT004
MIFTS: 30

Neonatal Respiratory Failure malady

Fetal diseases category

Summaries for Neonatal Respiratory Failure

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32MalaCards
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MalaCards: Neonatal Respiratory Failure, also known as respiratory failure of newborn, is related to respiratory failure and sensorineural hearing loss. An important gene associated with Neonatal Respiratory Failure is SFTPB (surfactant protein B). The compounds bleomycin and nacl have been mentioned in the context of this disorder. Affiliated tissues include lung, thyroid and kidney, and related mouse phenotype homeostasis/metabolism.

Aliases & Classifications for Neonatal Respiratory Failure

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Sources:
8Disease Ontology, 60UMLS, 56SNOMED-CT, 27ICD9CM, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


Aliases & Descriptions:

neonatal respiratory failure 8 60
respiratory failure of newborn 8


External Ids:

Disease Ontology8 DOID:11161
ICD9CM27 770.84
SNOMED-CT56 206317005, 95619009
ICD1025 P28.5

Related Diseases for Neonatal Respiratory Failure

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17GeneCards, 18GeneDecks
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Diseases related to Neonatal Respiratory Failure via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1respiratory failure31.4SFTPB
2sensorineural hearing loss10.2
3rhizomelic chondrodysplasia punctata10.0
4congenital hypothyroidism10.0
5neonatal leukemia10.0
6gestational diabetes10.0
7acute kidney failure10.0
8hypothyroidism10.0
9interstitial lung disease10.0
10myotonic dystrophy10.0
11rhizomelic chondrodysplasia punctata type 110.0
12bronchiolitis10.0APEX1
13cork-handlers' disease10.0SFTPB, APEX1
14lung cancer10.0APEX1, SFTPB

Graphical network of diseases related to Neonatal Respiratory Failure:



Diseases related to neonatal respiratory failure

Clinical Features for Neonatal Respiratory Failure

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Drugs & Therapeutics for Neonatal Respiratory Failure

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Neonatal Respiratory Failure

Drug clinical trials:

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Search NIH Clinical Center for Neonatal Respiratory Failure

Search CenterWatch for Neonatal Respiratory Failure

Genetic Tests for Neonatal Respiratory Failure

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Anatomical Context for Neonatal Respiratory Failure

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32MalaCards
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MalaCards organs/tissues related to Neonatal Respiratory Failure:

32
Lung, Thyroid, Kidney, Testes

Animal Models for Neonatal Respiratory Failure or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Neonatal Respiratory Failure:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.0ABCA7, TRPS1, APEX1, SFTPB

Publications for Neonatal Respiratory Failure

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50PubMed
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Articles related to Neonatal Respiratory Failure:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Neonatal lung disease and respiratory failure. (23573419)
2013
2
Outcome of extracorporeal membrane oxygenation for neonatal refractory respiratory failure. (24356661)
2013
3
Extracorporeal membrane oxygenation for neonatal and pediatric respiratory failure: an evidence-based review of the past decade (2002-2012). (24108118)
2013
4
Depletion of PHF14, a novel histone-binding protein gene, causes neonatal lethality in mice due to respiratory failure. (23688586)
2013
5
Novel NKX2.1 mutation associated with hypothyroidism and lethal respiratory failure in a full-term neonate. (23361500)
2013
6
Successful treatment of neonatal respiratory failure caused by a novel surfactant protein C p.Cys121Gly mutation with hydroxychloroquine. (23719253)
2013
7
Comparison of High Frequency Positive Pressure Mechanical Ventilation (HFPPV) With Conventional Method in the Treatment of Neonatal Respiratory Failure. (23983995)
2013
8
Neonatal paracorporeal lung assist device for respiratory failure. (23336880)
2013
9
The pulmonary circulation in neonatal respiratory failure. (22954275)
2012
10
The Microcirculation Is Unchanged in Neonates with Severe Respiratory Failure after the Initiation of ECMO Treatment. (22675619)
2012
11
Morbidity and mortality of neonatal respiratory failure in China: surfactant treatment in very immature infants. (22331337)
2012
12
Nitric oxide in neonatal hypoxemic respiratory failure. (22372677)
2012
13
Acute management of neonatal respiratory failure due to crossed ectopic obstructed megaureter in a duplicated pelvic kidney. (21050823)
2011
14
Rhizomelic chondrodysplasia punctata type 1 and fulminant neonatal respiratory failure, a case report and discussion of pathophysiology. (22052861)
2011
15
Rescue high frequency oscillation in neonates with acute respiratory failure. (21555797)
2011
16
Mortality of neonatal respiratory failure related to socioeconomic factors in Hebei province of China. (21150226)
2011
17
Adjunctive pharmacotherapy in neonates with respiratory failure. (18851933)
2009
18
Extracorporeal membrane oxygenation for the treatment of neonatal respiratory failure. (19713207)
2009
19
Neonatal respiratory failure: a 12-month clinical epidemiologic study from 2004 to 2005 in China. (18450855)
2008
20
An association of gastroschisis and fatal respiratory distress: does prenatal bile aspiration cause early-onset respiratory failure in neonates? (18712400)
2008
21
Clinical correlations and pulmonary function at 8 years of age after severe neonatal respiratory failure. (17654569)
2007
22
Respiratory failure, juvenile myelomonocytic leukemia, and neonatal Noonan syndrome. (17414570)
2007
23
ABCA3 deficiency: neonatal respiratory failure and interstitial lung disease. (17142158)
2006
24
Neonatal respiratory failure associated with mutation in the surfactant protein C gene. (16355106)
2006
25
Continuous negative extrathoracic pressure (CNEP) in neonatal respiratory failure: correction. (16740893)
2006
26
Acinar dysplasia: a rare cause of neonatal respiratory failure. (15174801)
2004
27
Cost-effectiveness of inhaled nitric oxide in the treatment of neonatal respiratory failure in the United States. (14654609)
2003
28
Late-onset, progressive sensorineural hearing loss after severe neonatal respiratory failure. (11981395)
2002
29
Acute neonatal respiratory failure and Chlamydia trachomatis. (11287694)
2001
30
Intratracheal pulmonary ventilation in neonatal respiratory failure. (9934880)
1999
31
Experimental neonatal respiratory failure induced by lysophosphatidylcholine: effect of surfactant treatment. (9931201)
1999
32
Alveolar capillary dysplasia with misalignment of the pulmonary veins: a rare but fatal cause of neonatal respiratory failure. (9880707)
1998
33
Inhaled nitric oxide and hypoxic respiratory failure in infants with congenital diaphragmatic hernia. The Neonatal Inhaled Nitric Oxide Study Group (NINOS). (9190553)
1997
34
Early measurement of lung volume--a useful discriminator of neonatal respiratory failure severity. (8746375)
1996
35
Continuous negative extrathoracic pressure in neonatal respiratory failure. (8951269)
1996
36
Extracorporeal membrane oxygenation with veno-venous bypass and apneic oxygenation for treatment of severe neonatal respiratory failure. (8647586)
1995
37
A matched pairs analysis of venoarterial and venovenous extracorporeal life support in neonatal respiratory failure. (8573870)
1995
38
Extracorporeal life support for neonatal respiratory failure. A 20-year experience. (8092896)
1994
39
Venovenous compares favorably with venoarterial access for extracorporeal membrane oxygenation in neonatal respiratory failure. (8341073)
1993
40
Volume-controlled ventilation for severe neonatal respiratory failure. (10148240)
1992
41
Experimental neonatal respiratory failure induced by a monoclonal antibody to the hydrophobic surfactant-associated protein SP-B. (1945561)
1991
42
Extra corporeal membrane oxygenation (ECMO) for neonatal respiratory failure. (2131304)
1990
43
Extracorporeal membrane oxygenation in the treatment of neonatal respiratory failure. (2121119)
1990
44
Extracorporeal membrane oxygenation in neonatal respiratory failure. A brief overview. (2681581)
1989
45
Extracorporeal membrane oxygenation for neonatal respiratory failure. (3547704)
1987
46
Extracorporeal circulation in neonatal respiratory failure: a prospective randomized study. (3900904)
1985
47
The management of neonatal respiratory failure. (7183845)
1982
48
Management of neonatal respiratory failure. (328868)
1977
49
Developmental follow-up of survivors of neonatal respiratory failure. (4815739)
1974
50
Gastrostomy in neonatal respiratory failure. (4161617)
1966

Genetic Variations for Neonatal Respiratory Failure

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Expression for genes affiliated with Neonatal Respiratory Failure

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neonatal Respiratory Failure

Search GEO for disease gene expression data for Neonatal Respiratory Failure.

Pathways for genes affiliated with Neonatal Respiratory Failure

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Compounds for genes affiliated with Neonatal Respiratory Failure

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Sources:
44Novoseek, 11DrugBank, 2BitterDB, 24HMDB
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Compounds related to Neonatal Respiratory Failure according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1bleomycin44 1110.5APEX1, SFTPB
2nacl449.5APEX1, SFTPB
3polyacrylamide449.4SFTPB, APEX1
4chloramphenicol44 2 1111.3SFTPB, APEX1
5phospholipid449.3ABCA7, SFTPB
6ascorbic acid44 2410.1APEX1, SFTPB

GO Terms for genes affiliated with Neonatal Respiratory Failure

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Products for genes affiliated with Neonatal Respiratory Failure

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neonatal Respiratory Failure

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet