MCID: NNT025
MIFTS: 16

Neonatal Systemic Lupus Erythematosus

Categories: Rare diseases, Bone diseases

Aliases & Classifications for Neonatal Systemic Lupus Erythematosus

MalaCards integrated aliases for Neonatal Systemic Lupus Erythematosus:

Name: Neonatal Systemic Lupus Erythematosus 49 69
Congenital Lupus Erythematosus 49
Neonatal Lupus Syndrome 49
Congenital Lupus 49
Neonatal Lupus 49
Neonatal Sle 49

Classifications:



External Ids:

UMLS 69 C0409979

Summaries for Neonatal Systemic Lupus Erythematosus

MalaCards based summary : Neonatal Systemic Lupus Erythematosus, also known as congenital lupus erythematosus, is related to neonatal lupus erythematosus and atrial standstill 1. The drugs Rho(D) Immune Globulin and gamma-Globulins have been mentioned in the context of this disorder. Affiliated tissues include heart.

Related Diseases for Neonatal Systemic Lupus Erythematosus

Diseases in the Neonatal Lupus Erythematosus family:

Neonatal Systemic Lupus Erythematosus

Diseases related to Neonatal Systemic Lupus Erythematosus via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 neonatal lupus erythematosus 11.3
2 atrial standstill 1 9.9
3 heart block, congenital 9.9
4 systemic lupus erythematosus 9.8
5 lupus erythematosus 9.8
6 chondrodysplasia punctata syndrome 9.6
7 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 9.6

Graphical network of the top 20 diseases related to Neonatal Systemic Lupus Erythematosus:



Diseases related to Neonatal Systemic Lupus Erythematosus

Symptoms & Phenotypes for Neonatal Systemic Lupus Erythematosus

Drugs & Therapeutics for Neonatal Systemic Lupus Erythematosus

Drugs for Neonatal Systemic Lupus Erythematosus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 27)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Rho(D) Immune Globulin Phase 2, Phase 3
2 gamma-Globulins Phase 2, Phase 3
3 Immunoglobulins Phase 2, Phase 3
4 Immunoglobulins, Intravenous Phase 2, Phase 3
5 Antibodies Phase 2, Phase 3
6 Autoantibodies Phase 2, Phase 3
7
Hydroxychloroquine Approved Phase 2 118-42-3 3652
8 Anti-Infective Agents Phase 2
9 Antimalarials Phase 2
10 Antiprotozoal Agents Phase 2
11 Antiparasitic Agents Phase 2
12 Antirheumatic Agents Phase 2
13
Dexamethasone Approved, Investigational, Vet_approved 50-02-2 5743
14 Dexamethasone acetate 1177-87-3
15 glucocorticoids
16
protease inhibitors
17 Gastrointestinal Agents
18 HIV Protease Inhibitors
19 Hormone Antagonists
20 Hormones
21 Hormones, Hormone Substitutes, and Hormone Antagonists
22 Peripheral Nervous System Agents
23 Antiemetics
24 Anti-Inflammatory Agents
25 Antineoplastic Agents, Hormonal
26 BB 1101
27 Autonomic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Preventive IVIG Therapy for Congenital Heart Block Completed NCT00460928 Phase 2, Phase 3 intravenous immune globulin (IVIG)
2 Preventive Approach to Congenital Heart Block With Hydroxychloroquine Recruiting NCT01379573 Phase 2 Hydroxychloroquine
3 Dexamethasone Treatment for Congenital Heart Block (CHB) in Newborns With Lupus Completed NCT00007358 Dexamethasone or other corticosteroid
4 The Research Registry for Neonatal Lupus Recruiting NCT00074373
5 Prospective Maternal Surveillance of SSA (Sjögren Syndrome A) Positive Pregnancies Using a Hand-held Fetal Heart Rate Monitor Recruiting NCT02920346

Search NIH Clinical Center for Neonatal Systemic Lupus Erythematosus

Genetic Tests for Neonatal Systemic Lupus Erythematosus

Anatomical Context for Neonatal Systemic Lupus Erythematosus

MalaCards organs/tissues related to Neonatal Systemic Lupus Erythematosus:

38
Heart

Publications for Neonatal Systemic Lupus Erythematosus

Articles related to Neonatal Systemic Lupus Erythematosus:

# Title Authors Year
1
Neonatal Systemic Lupus Erythematosus Syndrome: a Comprehensive Review. ( 29116459 )
2017

Variations for Neonatal Systemic Lupus Erythematosus

Expression for Neonatal Systemic Lupus Erythematosus

Search GEO for disease gene expression data for Neonatal Systemic Lupus Erythematosus.

Pathways for Neonatal Systemic Lupus Erythematosus

GO Terms for Neonatal Systemic Lupus Erythematosus

Sources for Neonatal Systemic Lupus Erythematosus

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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