MCID: NNT003
MIFTS: 27

Neonatal Thyrotoxicosis malady

Category: Endocrine diseases

Aliases & Classifications for Neonatal Thyrotoxicosis

About this section

Summaries for Neonatal Thyrotoxicosis

About this section
MalaCards based summary: Neonatal Thyrotoxicosis is related to primary fanconi syndrome and thyroiditis. An important gene associated with Neonatal Thyrotoxicosis is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. Affiliated tissues include thyroid, heart and pituitary, and related mouse phenotypes are reproductive system and homeostasis/metabolism.

Related Diseases for Neonatal Thyrotoxicosis

About this section

Diseases related to Neonatal Thyrotoxicosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
idRelated DiseaseScoreTop Affiliating Genes
1primary fanconi syndrome10.2LHX3, PROP1
2thyroiditis10.2
3complete lcat deficiency10.2LHX3, PROP1
4fallopian tube clear cell adenocarcinoma10.2LHX3, PROP1
5diabetes insipidus10.2LHX3, PROP1
6hypertelorism, preauricular sinus, punctal pits, and deafness10.1TSHR, TXNRD2
7molybdenum cofactor deficiency b10.1LHX3, PROP1
8mental retardation, x-linked syndromic, christianson type10.1LHX3, PROP1
9lung occult large cell carcinoma10.0TSHR, TXNRD2
10crohn's disease of the esophagus10.0PAX8, TSHR
11acquired central diabetes insipidus10.0PAX8, TSHR
12hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.0PAX8, TSHR
13hyperthyroidism9.9
14meningovascular neurosyphilis9.9PAX8, TSHR
15pulmonary hypertension9.8
16hypothyroidism9.8
17primary bacterial infectious disease9.8PAX8, TSHR
18kidney benign neoplasm9.8PAX8, TSHR
19richter's syndrome9.7PAX8, TSHR
20thyroid hormone resistance9.7
21congestive heart failure9.7
22craniosynostosis9.7
23graves' disease9.7
24infertility9.7
25hypertensive encephalopathy9.7
26hypoglycemia9.7
27encephalopathy9.7
28echinostomiasis9.7PAX8, TSHR
29chorea, hereditary benign9.7PAX8, TSHR
30atrial standstill9.6PAX8, TSHR
31atheroembolism of kidney9.5DIO3, PAX8, TSHR
32central nervous system hemangioma9.4PAX8, TSHR, TXNRD2
33frontotemporal dementia and/or amyotrophic lateral sclerosis 49.4PAX8, TSHR
34olecranon bursitis7.5DIO3, LCT, LHX3, PAX8, PROP1, TSHR

Graphical network of the top 20 diseases related to Neonatal Thyrotoxicosis:



Diseases related to neonatal thyrotoxicosis

Symptoms for Neonatal Thyrotoxicosis

About this section

Drugs & Therapeutics for Neonatal Thyrotoxicosis

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Neonatal Thyrotoxicosis

Genetic Tests for Neonatal Thyrotoxicosis

About this section

Anatomical Context for Neonatal Thyrotoxicosis

About this section

MalaCards organs/tissues related to Neonatal Thyrotoxicosis:

34
Thyroid, Heart, Pituitary, Testes

Animal Models for Neonatal Thyrotoxicosis or affiliated genes

About this section

MGI Mouse Phenotypes related to Neonatal Thyrotoxicosis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.0DIO3, LHX3, PAX8, PROP1, TSHR
2MP:00053767.2DIO3, LHX3, PAX8, PROP1, TSHR, TXNRD2
3MP:00107686.9DIO3, LHX3, PAX8, PROP1, TSHR, TXNRD2

Publications for Neonatal Thyrotoxicosis

About this section

Articles related to Neonatal Thyrotoxicosis:

(show top 50)    (show all 56)
idTitleAuthorsYear
1
Neonatal thyrotoxicosis caused by maternal autoimmune hyperthyroidism. (25750228)
2015
2
Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature. (25153577)
2014
3
Images in clinical medicine. Neonatal thyrotoxicosis. (24670170)
2014
4
Fetal and neonatal thyrotoxicosis. (24251220)
2013
5
Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. (22669869)
2012
6
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review. (18558604)
2008
7
A case report of neonatal thyrotoxicosis due to maternal autoimmune hyperthyroidism. (14695499)
2003
8
Neonatal thyrotoxicosis and conjugated hyperbilirubinemia. (12962270)
2003
9
Neonatal thyrotoxicosis and maternal infertility in thyroid hormone resistance due to a mutation in the TRbeta gene (M313T). (12201835)
2002
10
Congenital neonatal thyrotoxicosis and previous maternal radioiodine therapy. (10797041)
2000
11
Hypertensive encephalopathy in a patient with neonatal thyrotoxicosis. (10486076)
1999
12
Congenital chylothorax in neonatal thyrotoxicosis. (10685206)
1999
13
Thyrotropin receptor antibodies associated with post-operative relapse of thyrotoxicosis in a pregnancy complicated by neonatal thyrotoxicosis. (2315685)
1990
14
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis. (2874029)
1986
15
Diminished thyroid-stimulating hormone secretion associated with neonatal thyrotoxicosis. (3093659)
1986
16
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. (2859196)
1985
17
Effects of L-thyroxine treatment on pituitary GH content of adult rats with neonatal thyrotoxicosis. (6637335)
1983
18
Complications of propranolol use in neonatal thyrotoxicosis. (7395835)
1980
19
Neonatal thyrotoxicosis: a rare pediatric emergency. (6893645)
1980
20
Is propranolol alone really beneficial in neonatal thyrotoxicosis? Bradycardia and hypoglycemia evoke the doctrine of primum non nocere. (6998280)
1980
21
Neonatal thyrotoxicosis: intellectual impairment and craniosynostosis in later years. (7400892)
1980
22
Oxygen consumption in the rat following neonatal thyrotoxicosis. (488304)
1979
23
Neonatal thyrotoxicosis in four siblings born to a previously thyrotoxic mother. (717342)
1978
24
The role of thyroid stimulating immunoglobulins of Graves's disease in neonatal thyrotoxicosis. (581471)
1978
25
Neonatal thyrotoxicosis following maternal hypothyroidism. (619059)
1978
26
Neonatal thyrotoxicosis: alterations in serum concentrations of LATS-protector, T4, T3, reverse T3, and 3,3'T2. (650321)
1978
27
The behaviour of thyroid hormones in an infant with untreated neonatal thyrotoxicosis. (908154)
1977
28
Neonatal thyrotoxicosis. (909013)
1977
29
The possible relation between postpartum exacerbation of hyperthyroidism and neonatal thyrotoxicosis. (596245)
1977
30
Neonatal thyrotoxicosis with long acting thyroid stimulator-protector. (576864)
1977
31
Neonatal thyrotoxicosis. (899782)
1977
32
Humoral and genetic factors in thyrotoxic Graves disease and neonatal thyrotoxicosis. (946443)
1976
33
Attempted prevention of neonatal thyrotoxicosis. (990790)
1976
34
Attempted prevention of neonatal thyrotoxicosis. (1000245)
1976
35
Neonatal thyrotoxicosis is associated with transplacental passage of human thyroid stimulating immunoglobulin (HTSI). (962368)
1976
36
Congestive heart failure in neonatal thyrotoxicosis. A curable casue of heart failure in the newborn. (1192685)
1975
37
Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat. (4208653)
1974
38
Neonatal thyrotoxicosis treated with propranolol. (4429365)
1974
39
Propranolol in treatment of neonatal thyrotoxicosis. (4757519)
1973
40
Neonatal thyrotoxicosis. (4800423)
1973
41
Skeletal changes in neonatal thyrotoxicosis. (5008137)
1972
42
The role of long acting thyroid stimulator in neonatal thyrotoxicosis. (4677121)
1972
43
Neonatal thyrotoxicosis. Elevated long-acting thyroid stimulator (LATS) in mother and infant. (5762465)
1969
44
Neonatal thyrotoxicosis. (4185737)
1969
45
Neonatal thyrotoxicosis. (5645973)
1968
46
A case of neonatal thyrotoxicosis. (5588736)
1967
47
Neonatal thyrotoxicosis associated with maternal hypothyroidism. (4159675)
1966
48
Neonatal thyrotoxicosis: report of three cases involving four infants. (4168753)
1966
49
Survival time of circulating long-acting thyroid stimulator in neonatal thyrotoxicosis: implications for diagnosis and therapy of the disorder. (5846829)
1965
50
Neonatal thyrotoxicosis. (13731873)
1960

Variations for Neonatal Thyrotoxicosis

About this section

Expression for genes affiliated with Neonatal Thyrotoxicosis

About this section
Search GEO for disease gene expression data for Neonatal Thyrotoxicosis.

Pathways for genes affiliated with Neonatal Thyrotoxicosis

About this section

Pathways related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3DIO3, TXNRD2
29.3DIO3, TXNRD2

GO Terms for genes affiliated with Neonatal Thyrotoxicosis

About this section

Biological processes related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1thyroid-stimulating hormone signaling pathwayGO:00381949.8PAX8, TSHR
2animal organ morphogenesisGO:00098879.8LHX3, PROP1
3positive regulation of multicellular organism growthGO:00400189.6DIO3, TSHR
4dorsal/ventral pattern formationGO:00099539.4LHX3, PROP1
5central nervous system developmentGO:00074178.8PAX8, PROP1

Molecular functions related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1thyroid-stimulating hormone receptor activityGO:00049969.3PAX8, TSHR

Sources for Neonatal Thyrotoxicosis

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet