MCID: NNT003
MIFTS: 27

Neonatal Thyrotoxicosis malady

Categories: Endocrine diseases

Aliases & Classifications for Neonatal Thyrotoxicosis

Aliases & Descriptions for Neonatal Thyrotoxicosis:

Name: Neonatal Thyrotoxicosis 12 52 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:12573
ICD10 33 P72.1
ICD9CM 35 775.3
NCIt 47 C114906
SNOMED-CT 64 13795004
UMLS 69 C0158983

Summaries for Neonatal Thyrotoxicosis

MalaCards based summary : Neonatal Thyrotoxicosis is related to shaver's disease and idiopathic hypersomnia without long sleep time. An important gene associated with Neonatal Thyrotoxicosis is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways/superpathways are Human Thyroid Stimulating Hormone (TSH) signaling pathway and Selenium Metabolism and Selenoproteins. Affiliated tissues include thyroid, heart and pituitary, and related phenotypes are homeostasis/metabolism and mortality/aging

Related Diseases for Neonatal Thyrotoxicosis

Diseases related to Neonatal Thyrotoxicosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
id Related Disease Score Top Affiliating Genes
1 shaver's disease 10.1 LHX3 PROP1
2 idiopathic hypersomnia without long sleep time 10.1 LHX3 PROP1
3 thyroiditis 10.1
4 early-onset glaucoma 10.1 LHX3 PROP1
5 aminoacylase 1 deficiency 10.1 LHX3 PROP1
6 ossification of the posterior longitudinal ligament of spine 10.1 LHX3 PROP1
7 adult i blood group with or without congenital cataract 10.1 LHX3 PROP1
8 hypothyroidism, congenital, nongoitrous, 1 10.1 TSHR TXNRD2
9 mucopolysaccharidosis type vi 10.1 LHX3 PROP1
10 urethra clear cell adenocarcinoma 10.1 LHX3 PROP1
11 neuhauser daly magnelli syndrome 10.0 PAX8 TSHR
12 mesocardia 10.0 PAX8 TSHR
13 neuronopathy, distal hereditary motor, type viia 10.0 PAX8 TSHR
14 exanthema subitum 10.0 PAX8 TSHR
15 autoimmune hemolytic anemia 10.0 TSHR TXNRD2
16 cervix squamous papilloma 10.0 LHX3 PROP1
17 peritoneal serous papillary adenocarcinoma 9.9 PAX8 TSHR
18 commensal bacterial infectious disease 9.9 PAX8 TSHR
19 tenosynovitis of foot and ankle 9.9 PAX8 TSHR
20 hypothyroidism 9.8
21 hyperthyroidism 9.8
22 otosclerosis 9.8 PAX8 TSHR TXNRD2
23 choreoathetosis, hypothyroidism, and neonatal respiratory distress 9.8 PAX8 TSHR
24 pulmonary hypertension 9.7
25 cholesterol embolism 9.6 DIO3 PAX8 PROP1 TSHR
26 aflatoxins-related hepatocellular carcinoma 9.6 DIO3 PAX8 TSHR TXNRD2
27 thyroid hormone resistance 9.6
28 congestive heart failure 9.6
29 craniosynostosis 9.6
30 graves' disease 9.6
31 infertility 9.6
32 hypertensive encephalopathy 9.6
33 hypoglycemia 9.6
34 encephalopathy 9.6
35 potter's syndrome 9.0 DIO3 LCT LHX3 PAX8 PROP1 TSHR

Graphical network of the top 20 diseases related to Neonatal Thyrotoxicosis:



Diseases related to Neonatal Thyrotoxicosis

Symptoms & Phenotypes for Neonatal Thyrotoxicosis

MGI Mouse Phenotypes related to Neonatal Thyrotoxicosis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.63 DIO3 LHX3 PAX8 PROP1 TSHR TXNRD2
2 mortality/aging MP:0010768 9.43 DIO3 LHX3 PAX8 PROP1 TSHR TXNRD2
3 reproductive system MP:0005389 9.02 PROP1 TSHR DIO3 LHX3 PAX8

Drugs & Therapeutics for Neonatal Thyrotoxicosis

Search Clinical Trials , NIH Clinical Center for Neonatal Thyrotoxicosis

Genetic Tests for Neonatal Thyrotoxicosis

Anatomical Context for Neonatal Thyrotoxicosis

MalaCards organs/tissues related to Neonatal Thyrotoxicosis:

39
Thyroid, Heart, Pituitary, Testes

Publications for Neonatal Thyrotoxicosis

Articles related to Neonatal Thyrotoxicosis:

(show top 50) (show all 57)
id Title Authors Year
1
Fetal/neonatal Thyrotoxicosis in a Newborn From a Hypothyroid Woman With Hashimoto's Thyroiditis. ( 27813690 )
2016
2
Neonatal thyrotoxicosis caused by maternal autoimmune hyperthyroidism. ( 25750228 )
2015
3
Neonatal thyrotoxicosis with severe supraventricular tachycardia: case report and review of the literature. ( 25153577 )
2014
4
Images in clinical medicine. Neonatal thyrotoxicosis. ( 24670170 )
2014
5
Fetal and neonatal thyrotoxicosis. ( 24251220 )
2013
6
Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. ( 22669869 )
2012
7
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review. ( 18558604 )
2008
8
Neonatal thyrotoxicosis and persistent pulmonary hypertension necessitating extracorporeal life support. ( 15629961 )
2005
9
A case report of neonatal thyrotoxicosis due to maternal autoimmune hyperthyroidism. ( 14695499 )
2003
10
Neonatal thyrotoxicosis and conjugated hyperbilirubinemia. ( 12962270 )
2003
11
Neonatal thyrotoxicosis and maternal infertility in thyroid hormone resistance due to a mutation in the TRbeta gene (M313T). ( 12201835 )
2002
12
The relationship between maternal serum thyroid-stimulating immunoglobulin and fetal and neonatal thyrotoxicosis. ( 12052596 )
2002
13
Congenital neonatal thyrotoxicosis and previous maternal radioiodine therapy. ( 10797041 )
2000
14
Hypertensive encephalopathy in a patient with neonatal thyrotoxicosis. ( 10486076 )
1999
15
Congenital chylothorax in neonatal thyrotoxicosis. ( 10685206 )
1999
16
Thyrotropin receptor antibodies associated with post-operative relapse of thyrotoxicosis in a pregnancy complicated by neonatal thyrotoxicosis. ( 2315685 )
1990
17
Diminished thyroid-stimulating hormone secretion associated with neonatal thyrotoxicosis. ( 3093659 )
1986
18
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis. ( 2874029 )
1986
19
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. ( 2859196 )
1985
20
Effects of L-thyroxine treatment on pituitary GH content of adult rats with neonatal thyrotoxicosis. ( 6637335 )
1983
21
Hypertension in neonatal thyrotoxicosis. ( 7069539 )
1982
22
Neonatal thyrotoxicosis: a rare pediatric emergency. ( 6893645 )
1980
23
Complications of propranolol use in neonatal thyrotoxicosis. ( 7395835 )
1980
24
Neonatal thyrotoxicosis: intellectual impairment and craniosynostosis in later years. ( 7400892 )
1980
25
Is propranolol alone really beneficial in neonatal thyrotoxicosis? Bradycardia and hypoglycemia evoke the doctrine of primum non nocere. ( 6998280 )
1980
26
Oxygen consumption in the rat following neonatal thyrotoxicosis. ( 488304 )
1979
27
Neonatal thyrotoxicosis: alterations in serum concentrations of LATS-protector, T4, T3, reverse T3, and 3,3'T2. ( 650321 )
1978
28
Neonatal thyrotoxicosis following maternal hypothyroidism. ( 619059 )
1978
29
The role of thyroid stimulating immunoglobulins of Graves's disease in neonatal thyrotoxicosis. ( 581471 )
1978
30
Neonatal thyrotoxicosis in four siblings born to a previously thyrotoxic mother. ( 717342 )
1978
31
The possible relation between postpartum exacerbation of hyperthyroidism and neonatal thyrotoxicosis. ( 596245 )
1977
32
Neonatal thyrotoxicosis. ( 899782 )
1977
33
Neonatal thyrotoxicosis associated with the hyperviscosity syndrome. ( 830919 )
1977
34
Neonatal thyrotoxicosis. ( 909013 )
1977
35
Neonatal thyrotoxicosis with long acting thyroid stimulator-protector. ( 576864 )
1977
36
The behaviour of thyroid hormones in an infant with untreated neonatal thyrotoxicosis. ( 908154 )
1977
37
Attempted prevention of neonatal thyrotoxicosis. ( 1000245 )
1976
38
Attempted prevention of neonatal thyrotoxicosis. ( 990790 )
1976
39
Humoral and genetic factors in thyrotoxic Graves disease and neonatal thyrotoxicosis. ( 946443 )
1976
40
Neonatal thyrotoxicosis is associated with transplacental passage of human thyroid stimulating immunoglobulin (HTSI). ( 962368 )
1976
41
Congestive heart failure in neonatal thyrotoxicosis. A curable casue of heart failure in the newborn. ( 1192685 )
1975
42
Neonatal thyrotoxicosis. ( 1134079 )
1975
43
Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat. ( 4208653 )
1974
44
Neonatal thyrotoxicosis treated with propranolol. ( 4429365 )
1974
45
Propranolol in treatment of neonatal thyrotoxicosis. ( 4757519 )
1973
46
Neonatal thyrotoxicosis. ( 4800423 )
1973
47
The role of long acting thyroid stimulator in neonatal thyrotoxicosis. ( 4677121 )
1972
48
Skeletal changes in neonatal thyrotoxicosis. ( 5008137 )
1972
49
Neonatal thyrotoxicosis. Elevated long-acting thyroid stimulator (LATS) in mother and infant. ( 5762465 )
1969
50
Neonatal thyrotoxicosis. ( 4185737 )
1969

Variations for Neonatal Thyrotoxicosis

Expression for Neonatal Thyrotoxicosis

Search GEO for disease gene expression data for Neonatal Thyrotoxicosis.

Pathways for Neonatal Thyrotoxicosis

Pathways related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.79 PAX8 TSHR
2 10.29 DIO3 TXNRD2

GO Terms for Neonatal Thyrotoxicosis

Biological processes related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 transcription from RNA polymerase II promoter GO:0006366 9.43 LHX3 PAX8 PROP1
2 central nervous system development GO:0007417 9.37 PAX8 PROP1
3 animal organ morphogenesis GO:0009887 9.32 LHX3 PROP1
4 dorsal/ventral pattern formation GO:0009953 9.16 LHX3 PROP1
5 positive regulation of multicellular organism growth GO:0040018 8.96 DIO3 TSHR
6 thyroid-stimulating hormone signaling pathway GO:0038194 8.62 PAX8 TSHR

Molecular functions related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sequence-specific DNA binding GO:0043565 9.13 LHX3 PAX8 PROP1
2 thyroid-stimulating hormone receptor activity GO:0004996 8.62 PAX8 TSHR

Sources for Neonatal Thyrotoxicosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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