MCID: NNT003
MIFTS: 28

Neonatal Thyrotoxicosis malady

Category: Endocrine diseases

Aliases & Classifications for Neonatal Thyrotoxicosis

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Aliases & Descriptions for Neonatal Thyrotoxicosis:

Name: Neonatal Thyrotoxicosis 10 47 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:12573
ICD1027 P72.1
SNOMED-CT59 13795004
ICD9CM29 775.3
UMLS65 C0158983

Summaries for Neonatal Thyrotoxicosis

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MalaCards based summary: Neonatal Thyrotoxicosis is related to inherited predisposition to essential thrombocythemia and complement component 8 deficiency. An important gene associated with Neonatal Thyrotoxicosis is TSHR (Thyroid Stimulating Hormone Receptor), and among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. Affiliated tissues include bone, brain and skeletal muscle, and related mouse phenotypes are reproductive system and nervous system.

Related Diseases for Neonatal Thyrotoxicosis

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Diseases related to Neonatal Thyrotoxicosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 69)
idRelated DiseaseScoreTop Affiliating Genes
1inherited predisposition to essential thrombocythemia10.2LHX3, PROP1
2complement component 8 deficiency10.1LHX3, PROP1
3septooptic dysplasia10.1LHX3, PROP1
4acute myeloid leukemia, flt3-related10.1LHX3, PROP1
5eyelid disease10.1LHX3, PROP1
6molybdenum cofactor deficiency b10.1LHX3, PROP1
7hypertelorism, preauricular sinus, punctal pits, and deafness10.1TSHR, TXNRD2
8pituitary adenoma, growth hormone-secreting 210.1LHX3, PROP1
9rheumatoid arthritis10.1
10arthritis10.1
11cholestasis10.1
12neuronitis10.1
13strictly posterior acute myocardial infarction10.1LHX3, PROP1
14lung occult adenocarcinoma10.0TSHR, TXNRD2
15iatrogenic or traumatic pituitary deficiency10.0PAX8, TSHR
16hypothyroidism, congenital, due to thyroid dysgenesis or hypoplasia10.0PAX8, TSHR
17mediastinal osteogenic sarcoma9.9PAX8, TSHR
18colorectal cancer9.9
19hiv-19.9
20coronary artery disease9.9
21alkaptonuria9.9
22pancreatic cancer9.9
23choroideremia9.9
24alcoholic liver cirrhosis9.9
25chronic inflammatory demyelinating polyneuropathy9.9
26holoprosencephaly9.9
27liver cirrhosis9.9
28myelofibrosis9.9
29adenoiditis9.9
30artery disease9.9
31sleep apnea9.9
32obstructive sleep apnea9.9
33bulimia nervosa9.9
34hemolytic-uremic syndrome9.9
35dementia9.9
36megaloblastic anemia9.9
37polyneuropathy9.9
38aggressive periodontitis9.9
39pericarditis9.9
40intrahepatic cholestasis9.9
41relapsing polychondritis9.9
42kidney cancer9.9
43papillary carcinoma9.9
44cerebritis9.9
45epithelioid trophoblastic tumor9.9
46primary syphilis9.9
47syphilis9.9
48pancreatitis9.9
49aortitis9.9
50demyelinating polyneuropathy9.9

Graphical network of the top 20 diseases related to Neonatal Thyrotoxicosis:



Diseases related to neonatal thyrotoxicosis

Symptoms for Neonatal Thyrotoxicosis

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Drugs & Therapeutics for Neonatal Thyrotoxicosis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Neonatal Thyrotoxicosis

Genetic Tests for Neonatal Thyrotoxicosis

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Anatomical Context for Neonatal Thyrotoxicosis

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MalaCards organs/tissues related to Neonatal Thyrotoxicosis:

33
Bone, Brain, Skeletal muscle, Breast, Prostate, Ovary

Animal Models for Neonatal Thyrotoxicosis or affiliated genes

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MGI Mouse Phenotypes related to Neonatal Thyrotoxicosis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053898.0DIO3, LHX3, PAX8, PROP1, TSHR
2MP:00036317.7LHX3, PAX8, PROP1, TSHR, TXNRD2
3MP:00107687.2DIO3, LHX3, PAX8, PROP1, TSHR, TXNRD2
4MP:00053766.9DIO3, LHX3, PAX8, PROP1, TSHR, TXNRD2

Publications for Neonatal Thyrotoxicosis

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Articles related to Neonatal Thyrotoxicosis:

(show top 50)    (show all 56)
idTitleAuthorsYear
1
Cidofovir in the Treatment of BK Virus-Associated Hemorrhagic Cystitis after Allogeneic Hematopoietic Stem CellA Transplantation. (26718666)
2016
2
"Clinical characteristics and outcome of patients with autoimmune hemolytic anemia (AIHA) uniformly defined as primary by a diagnostic work-up". (27059006)
2016
3
Autoimmune Lymphoproliferative Syndrome with Red Cell Aplasia. (25972287)
2015
4
Effect of high-fat diet on peripheral neuropathy in C57BL/6 mice. (25404943)
2014
5
EGF rs11568835 G/A polymorphism is associated with increased risk of rheumatoid arthritis. (25089940)
2014
6
Overexpression of twist and matrix metalloproteinase-9 with metastasis and prognosis in gastric cancer. (24175775)
2013
7
Gender and factor-level interactions in psychopathy: implications for self-directed violence risk and borderline personality disorder symptoms. (22452771)
2012
8
The portrayal of down syndrome in prenatal screening information pamphlets. (22947408)
2012
9
Cyclophosphamide metabolite inducing apoptosis in RLS mouse lymphosarcoma cells is a substrate for P-glycoprotein. (22803083)
2012
10
Malignant peripheral nerve sheath tumor of the vagus nerve in a teenager with the neurofibromatosis 1 gene mutation: a case report. (21843710)
2011
11
Radial longitudinal deficiencies with hypoplastic/absent thumbs and cutaneous syndactyly of the most radial digits. (20807627)
2010
12
CD105 expression as a measure of microvessel density in supraglottic laryngeal squamous cell carcinoma. (19340447)
2009
13
Overexpressed focal adhesion kinase predicts a higher incidence of extrahepatic metastasis and worse survival in hepatocellular carcinoma. (19454363)
2009
14
A common mutation in paraoxonase-2 results in impaired lactonase activity. (19840942)
2009
15
Identification of a novel factor X deletion in combination with a missense mutation in the F10 gene - Genotype-phenotype correlation in a girl with severe factor X deficiency. (19404516)
2009
16
Effects of glucose, glycerol, 3-hydroxybutyrate, insulin, and leptin on placental growth hormone secretion in placental explants. (18246527)
2008
17
Interface membrane fibroblasts around aseptically loosened endoprostheses express MMP-13. (17853491)
2008
18
Antenatally diagnosed ovarian cyst with torsion managed laparoscopically. (20177484)
2008
19
Impairment of quality of life in parents of children and adolescents with pervasive developmental disorder. (17466072)
2007
20
Are Parkinson disease patients protected from some but not all cancers? (17699801)
2007
21
BS69, a corepressor interacting with ZHX1, is a bifunctional transcription factor. (17127430)
2007
22
Cardiovascular and gastrointestinal risks associated with selective and non-selective NSAIDs]. (17552414)
2007
23
Associations of the beta-fibrinogen Hae III and factor XIII Val34Leu gene variants with venous thrombosis. (17582472)
2007
24
Release of protein as well as activity of MMP-9 from unstable atherosclerotic plaques during percutaneous coronary intervention. (17927738)
2007
25
Regional distribution of heterozygous 657del5 mutation carriers of the NBS1 gene in Wielkopolska province (Poland). (16877808)
2006
26
Functional interaction between the glucocorticoid receptor and GANP/MCM3AP. (16914116)
2006
27
Is a leaky gut involved in the pathogenesis of intrahepatic cholestasis of pregnancy? (16557543)
2006
28
Association of a functional polymorphism in the CYP4A11 gene with systolic blood pressure in survivors of myocardial infarction. (16957555)
2006
29
Difference in ex vivo expansion of megakaryocytes derived from umbilical cord blood and peripheral blood]. (17274882)
2006
30
Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3. (15809299)
2005
31
An era of rapid advancement: diagnosis and treatment of metastatic brain cancer. (16237289)
2005
32
14-electron disilene palladium complex having strong pi-complex character. (15469264)
2004
33
Dimeric architecture of the human bumetanide-sensitive Na-K-Cl Co-transporter. (14638903)
2003
34
Association study between a polymorphism of aldosterone synthetase gene and the pathogenesis of polycystic ovary syndrome]. (12783697)
2003
35
Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells. (12444557)
2002
36
Relation of polymorphism in the promotor region for the human osteocalcin gene to bone mineral density and occurrence of osteoporosis in postmenopausal Chinese women in Taiwan. (11574953)
2001
37
The major immediate-early genes of human cytomegalovirus induce two novel proteins with molecular weights of 91 and 102 kilodaltons. (10948998)
2000
38
Congenital linear steatocystoma multiplex of the nose. (10792805)
2000
39
De-regulation of GRP stress protein expression in human breast cancer cell lines. (10424404)
1999
40
Uracil phosphoribosyltransferase activity in hereditary orotic aciduria. (10404744)
1999
41
How chaperones fold proteins. (9563819)
1998
42
Prognostic significance of progesterone receptor immunohistochemistry in endometrial carcinoma. (9648591)
1998
43
The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells. (9074633)
1997
44
Activation of the JNK pathway by distantly related protein kinases, MEKK and MUK. (8637721)
1996
45
Hematological features of patients with myelodysplastic syndromes associated with a chromosome 5q deletion. (7604812)
1995
46
Effects of IFN-beta on growth of human prostatic JCA-1 cells. (7909434)
1994
47
An error-correcting proofreading exonuclease-polymerase that copurifies with DNA-polymerase-alpha-primase. (8383685)
1993
48
Megaesophagus in mouse--histochemical studies. (3350294)
1988
49
Complete atrioventricular canal associated with conotruncal malformations: anatomical observations in 13 specimens. (421722)
1979
50
Colorado tick fever studies on chick embryo adapted virus. (20268419)
1947

Variations for Neonatal Thyrotoxicosis

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Expression for genes affiliated with Neonatal Thyrotoxicosis

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Search GEO for disease gene expression data for Neonatal Thyrotoxicosis.

Pathways for genes affiliated with Neonatal Thyrotoxicosis

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Pathways related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.3DIO3, TXNRD2
29.3DIO3, TXNRD2

GO Terms for genes affiliated with Neonatal Thyrotoxicosis

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Biological processes related to Neonatal Thyrotoxicosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1central nervous system developmentGO:00074179.5PAX8, PROP1
2positive regulation of transcription from RNA polymerase II promoterGO:00459448.7LHX3, PAX8, PROP1

Sources for Neonatal Thyrotoxicosis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet