MCID: NNT003
MIFTS: 33

Neonatal Thyrotoxicosis malady

Summaries for Neonatal Thyrotoxicosis

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32MalaCards
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MalaCards: Neonatal Thyrotoxicosis is related to thyrotoxicosis and thyroiditis. An important gene associated with Neonatal Thyrotoxicosis is TSHR (thyroid stimulating hormone receptor), and among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. The compounds iodine and methimazole have been mentioned in the context of this disorder. Affiliated tissues include thyroid, heart and pituitary, and related mouse phenotypes are endocrine/exocrine gland and nervous system.

Aliases & Classifications for Neonatal Thyrotoxicosis

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8Disease Ontology, 10DISEASES, 44Novoseek, 60UMLS, 56SNOMED-CT, 27ICD9CM
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Aliases & Descriptions:

neonatal thyrotoxicosis 8 10 44 60


External Ids:

Disease Ontology8 DOID:12573
SNOMED-CT56 13795004
ICD9CM27 775.3

Related Diseases for Neonatal Thyrotoxicosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Neonatal Thyrotoxicosis:



Diseases related to neonatal thyrotoxicosis

Clinical Features for Neonatal Thyrotoxicosis

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Drugs & Therapeutics for Neonatal Thyrotoxicosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Neonatal Thyrotoxicosis

Drug clinical trials:

Search ClinicalTrials for Neonatal Thyrotoxicosis

Search NIH Clinical Center for Neonatal Thyrotoxicosis

Search CenterWatch for Neonatal Thyrotoxicosis

Genetic Tests for Neonatal Thyrotoxicosis

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Anatomical Context for Neonatal Thyrotoxicosis

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32MalaCards
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MalaCards organs/tissues related to Neonatal Thyrotoxicosis:

32
Thyroid, Heart, Pituitary, Testes

Animal Models for Neonatal Thyrotoxicosis or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Neonatal Thyrotoxicosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.5PROP1, TSHR, TRH, LHX3
2MP:00036318.0TRH, PROP1, LHX3, TXNRD2, TSHR
3MP:00053898.0DIO3, TSHR, PROP1, LHX3
4MP:00053787.7TSHR, DIO3, LHX3, PROP1, TRH
5MP:00107687.6PROP1, DIO3, LHX3, TXNRD2, TSHR
6MP:00053767.2TSHR, TXNRD2, LHX3, DIO3, PROP1, TRH

Publications for Neonatal Thyrotoxicosis

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50PubMed
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Articles related to Neonatal Thyrotoxicosis:

(show top 50)    (show all 55)
idTitleAuthorsYear
1
Fetal and neonatal thyrotoxicosis. (24251220)
2013
2
Maternal thyrotoxicosis and fetal goitre requiring in utero therapy for hypothyroidism and subsequent neonatal therapy for hyperthyroidism. (23320593)
2013
3
Neonatal thyrotoxicosis presenting as persistent pulmonary hypertension. (22669869)
2012
4
Neonatal thyrotoxicosis and persistent pulmonary hypertension necessitating extracorporeal life support. (15629961)
2005
5
A case report of neonatal thyrotoxicosis due to maternal autoimmune hyperthyroidism. (14695499)
2003
6
Neonatal thyrotoxicosis and maternal infertility in thyroid hormone resistance due to a mutation in the TRbeta gene (M313T). (12201835)
2002
7
The relationship between maternal serum thyroid-stimulating immunoglobulin and fetal and neonatal thyrotoxicosis. (12052596)
2002
8
Hypertensive encephalopathy in a patient with neonatal thyrotoxicosis. (10486076)
1999
9
Congenital chylothorax in neonatal thyrotoxicosis. (10685206)
1999
10
Thyrotropin receptor antibodies associated with post-operative relapse of thyrotoxicosis in a pregnancy complicated by neonatal thyrotoxicosis. (2315685)
1990
11
Diminished thyroid-stimulating hormone secretion associated with neonatal thyrotoxicosis. (3093659)
1986
12
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis. (2874029)
1986
13
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. (2859196)
1985
14
Effects of L-thyroxine treatment on pituitary GH content of adult rats with neonatal thyrotoxicosis. (6637335)
1983
15
Complications of propranolol use in neonatal thyrotoxicosis. (7395835)
1980
16
Is propranolol alone really beneficial in neonatal thyrotoxicosis? Bradycardia and hypoglycemia evoke the doctrine of primum non nocere. (6998280)
1980
17
Neonatal thyrotoxicosis: a rare pediatric emergency. (6893645)
1980
18
Neonatal thyrotoxicosis: intellectual impairment and craniosynostosis in later years. (7400892)
1980
19
Oxygen consumption in the rat following neonatal thyrotoxicosis. (488304)
1979
20
Neonatal thyrotoxicosis in four siblings born to a previously thyrotoxic mother. (717342)
1978
21
The role of thyroid stimulating immunoglobulins of Graves's disease in neonatal thyrotoxicosis. (581471)
1978
22
Neonatal thyrotoxicosis: alterations in serum concentrations of LATS-protector, T4, T3, reverse T3, and 3,3'T2. (650321)
1978
23
Neonatal thyrotoxicosis following maternal hypothyroidism. (619059)
1978
24
The behaviour of thyroid hormones in an infant with untreated neonatal thyrotoxicosis. (908154)
1977
25
Thyrotoxicosis detected in a mass-screening program for neonatal hypothyroidism: demonstration of placental transfer of an immunoglobulin with marked lipolytic activity. (894408)
1977
26
Neonatal thyrotoxicosis. (899782)
1977
27
Neonatal thyrotoxicosis. (909013)
1977
28
The possible relation between postpartum exacerbation of hyperthyroidism and neonatal thyrotoxicosis. (596245)
1977
29
Neonatal thyrotoxicosis with long acting thyroid stimulator-protector. (576864)
1977
30
Neonatal thyrotoxicosis associated with the hyperviscosity syndrome. (830919)
1977
31
Neonatal thyrotoxicosis is associated with transplacental passage of human thyroid stimulating immunoglobulin (HTSI). (962368)
1976
32
Humoral and genetic factors in thyrotoxic Graves disease and neonatal thyrotoxicosis. (946443)
1976
33
Attempted prevention of neonatal thyrotoxicosis. (1000245)
1976
34
Congestive heart failure in neonatal thyrotoxicosis. A curable casue of heart failure in the newborn. (1192685)
1975
35
Neonatal thyrotoxicosis. (1134079)
1975
36
Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat. (4208653)
1974
37
Neonatal thyrotoxicosis treated with propranolol. (4429365)
1974
38
Propranolol in treatment of neonatal thyrotoxicosis. (4757519)
1973
39
Neonatal thyrotoxicosis. (4800423)
1973
40
The role of long acting thyroid stimulator in neonatal thyrotoxicosis. (4677121)
1972
41
Skeletal changes in neonatal thyrotoxicosis. (5008137)
1972
42
Neonatal thyrotoxicosis. Elevated long-acting thyroid stimulator (LATS) in mother and infant. (5762465)
1969
43
Neonatal thyrotoxicosis. (4185737)
1969
44
Neonatal thyrotoxicosis. (5645973)
1968
45
A case of neonatal thyrotoxicosis. (5588736)
1967
46
Neonatal thyrotoxicosis associated with maternal hypothyroidism. (4159675)
1966
47
Neonatal thyrotoxicosis: report of three cases involving four infants. (4168753)
1966
48
Survival time of circulating long-acting thyroid stimulator in neonatal thyrotoxicosis: implications for diagnosis and therapy of the disorder. (5846829)
1965
49
Neonatal thyrotoxicosis. (13731873)
1960
50
Neonatal thyrotoxicosis. (13667336)
1959

Genetic Variations for Neonatal Thyrotoxicosis

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Expression for genes affiliated with Neonatal Thyrotoxicosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neonatal Thyrotoxicosis

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Pathways for genes affiliated with Neonatal Thyrotoxicosis

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37NCBI BioSystems Database
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Pathways related to Neonatal Thyrotoxicosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0DIO3, TXNRD2
29.0DIO3, TXNRD2

Compounds for genes affiliated with Neonatal Thyrotoxicosis

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44Novoseek, 24HMDB, 2BitterDB, 11DrugBank
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Compounds related to Neonatal Thyrotoxicosis according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1iodine44 2410.8TSHR, TRH
2methimazole44 2 1111.7TRH, TSHR
3propylthiouracil44 2 1111.6TSHR, DIO3
4125i449.5TSHR, DIO3
5iodide44 2410.5DIO3, TSHR
6asparagine449.4TSHR, TXNRD2
7acth449.3TSHR, TRH, PROP1
8gnrh449.3LHX3, TRH, PROP1
9selenocysteine44 11 2411.3DIO3, TXNRD2
10cytosine44 2410.1TXNRD2, TSHR
11hydrogen44 2410.1TRH, TXNRD2, TSHR
12thymidine44 2410.0TXNRD2, TRH, TSHR
13dithiothreitol449.0DIO3, TRH
14arginine448.9TRH, TSHR, TXNRD2
15estradiol44 11 2410.9TRH, DIO3, TSHR
16tyrosine448.5TSHR, TRH, TXNRD2, LHX3
17cysteine448.4TSHR, TXNRD2, LHX3, DIO3
18triiodothyronine448.4TRH, TXNRD2, DIO3, TSHR
19thyroxine44 249.4TRH, DIO3, TXNRD2, TSHR

GO Terms for genes affiliated with Neonatal Thyrotoxicosis

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Products for genes affiliated with Neonatal Thyrotoxicosis

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Sources for Neonatal Thyrotoxicosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet