MCID: NNT003
MIFTS: 31

Neonatal Thyrotoxicosis malady

Endocrine diseases category
Download this MalaCard

Summaries for Neonatal Thyrotoxicosis

About this section
Sources:
33MalaCards
See all sources

Fully expand this MalaCard
MalaCards: Neonatal Thyrotoxicosis is related to thyrotoxicosis and hyperthyroidism. An important gene associated with Neonatal Thyrotoxicosis is TSHR (thyroid stimulating hormone receptor). The compounds triiodothyronine and asparagine have been mentioned in the context of this disorder. Affiliated tissues include thyroid, heart and pituitary, and related mouse phenotypes are hearing/vestibular/ear and nervous system.

Aliases & Classifications for Neonatal Thyrotoxicosis

About this section
Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 27ICD9CM, 58SNOMED-CT
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine diseases


Aliases & Descriptions:

neonatal thyrotoxicosis 8 10 45 62


External Ids:

Disease Ontology8 DOID:12573
SNOMED-CT58 13795004
ICD9CM27 775.3

Related Diseases for Neonatal Thyrotoxicosis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Neonatal Thyrotoxicosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 17)
idRelated DiseaseScoreTop Affiliating Genes
1thyrotoxicosis31.4TSHR, TXNRD2
2hyperthyroidism30.3TXNRD2, TSHR
3hypothyroidism30.2TSHR, TXNRD2, LHX3
4thyroiditis10.6
5hypertension10.3
6hypertensive encephalopathy10.0
7hypoglycemia10.0
8infertility10.0
9graves' disease10.0
10congestive heart failure10.0
11craniosynostosis10.0
12thyroid adenoma10.0TXNRD2, TSHR
13goiter10.0TSHR, TXNRD2
14papillary thyroid carcinoma10.0TXNRD2, TSHR
15adenoma10.0TSHR, TXNRD2
16thyroid cancer10.0TXNRD2, TSHR
17hypersensitivity reaction type ii disease10.0TXNRD2, TSHR

Graphical network of diseases related to Neonatal Thyrotoxicosis:



Diseases related to neonatal thyrotoxicosis

Symptoms for Neonatal Thyrotoxicosis

About this section

Drugs & Therapeutics for Neonatal Thyrotoxicosis

About this section
Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Neonatal Thyrotoxicosis

Search NIH Clinical Center for Neonatal Thyrotoxicosis

Genetic Tests for Neonatal Thyrotoxicosis

About this section

Anatomical Context for Neonatal Thyrotoxicosis

About this section
Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Neonatal Thyrotoxicosis:

33
Thyroid, Heart, Pituitary, Testes

Animal Models for Neonatal Thyrotoxicosis or affiliated genes

About this section
Sources:
37MGI
See all sources

MGI Mouse Phenotypes related to Neonatal Thyrotoxicosis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053778.7LHX3, TSHR
2MP:00036318.5LHX3, TXNRD2, TSHR
3MP:00107688.5LHX3, TXNRD2, TSHR
4MP:00053768.4LHX3, TXNRD2, TSHR

Publications for Neonatal Thyrotoxicosis

About this section
Sources:
52PubMed
See all sources

Articles related to Neonatal Thyrotoxicosis:

(show top 50)    (show all 53)
idTitleAuthorsYear
1
Fetal and neonatal thyrotoxicosis. (24251220)
2013
2
Persistent neonatal thyrotoxicosis in a neonate secondary to a rare thyroid-stimulating hormone receptor activating mutation: case report and literature review. (18558604)
2008
3
Neonatal thyrotoxicosis and persistent pulmonary hypertension necessitating extracorporeal life support. (15629961)
2005
4
A case report of neonatal thyrotoxicosis due to maternal autoimmune hyperthyroidism. (14695499)
2003
5
Neonatal thyrotoxicosis and conjugated hyperbilirubinemia. (12962270)
2003
6
Neonatal thyrotoxicosis and maternal infertility in thyroid hormone resistance due to a mutation in the TRbeta gene (M313T). (12201835)
2002
7
The relationship between maternal serum thyroid-stimulating immunoglobulin and fetal and neonatal thyrotoxicosis. (12052596)
2002
8
Congenital neonatal thyrotoxicosis and previous maternal radioiodine therapy. (10797041)
2000
9
Hypertensive encephalopathy in a patient with neonatal thyrotoxicosis. (10486076)
1999
10
Congenital chylothorax in neonatal thyrotoxicosis. (10685206)
1999
11
Thyrotropin receptor antibodies associated with post-operative relapse of thyrotoxicosis in a pregnancy complicated by neonatal thyrotoxicosis. (2315685)
1990
12
Diminished thyroid-stimulating hormone secretion associated with neonatal thyrotoxicosis. (3093659)
1986
13
Thyroid-stimulating immunoglobulins and thyroid function tests in two siblings with neonatal thyrotoxicosis. (2874029)
1986
14
Neonatal thyrotoxicosis treated with exchange transfusion and Lugol's iodine. (2859196)
1985
15
Effects of L-thyroxine treatment on pituitary GH content of adult rats with neonatal thyrotoxicosis. (6637335)
1983
16
Complications of propranolol use in neonatal thyrotoxicosis. (7395835)
1980
17
Is propranolol alone really beneficial in neonatal thyrotoxicosis? Bradycardia and hypoglycemia evoke the doctrine of primum non nocere. (6998280)
1980
18
Neonatal thyrotoxicosis: a rare pediatric emergency. (6893645)
1980
19
Neonatal thyrotoxicosis: intellectual impairment and craniosynostosis in later years. (7400892)
1980
20
Oxygen consumption in the rat following neonatal thyrotoxicosis. (488304)
1979
21
Neonatal thyrotoxicosis in four siblings born to a previously thyrotoxic mother. (717342)
1978
22
The role of thyroid stimulating immunoglobulins of Graves's disease in neonatal thyrotoxicosis. (581471)
1978
23
Neonatal thyrotoxicosis: alterations in serum concentrations of LATS-protector, T4, T3, reverse T3, and 3,3'T2. (650321)
1978
24
Neonatal thyrotoxicosis following maternal hypothyroidism. (619059)
1978
25
The behaviour of thyroid hormones in an infant with untreated neonatal thyrotoxicosis. (908154)
1977
26
Neonatal thyrotoxicosis. (899782)
1977
27
Neonatal thyrotoxicosis. (909013)
1977
28
The possible relation between postpartum exacerbation of hyperthyroidism and neonatal thyrotoxicosis. (596245)
1977
29
Neonatal thyrotoxicosis with long acting thyroid stimulator-protector. (576864)
1977
30
Neonatal thyrotoxicosis associated with the hyperviscosity syndrome. (830919)
1977
31
Neonatal thyrotoxicosis is associated with transplacental passage of human thyroid stimulating immunoglobulin (HTSI). (962368)
1976
32
Humoral and genetic factors in thyrotoxic Graves disease and neonatal thyrotoxicosis. (946443)
1976
33
Attempted prevention of neonatal thyrotoxicosis. (990790)
1976
34
Attempted prevention of neonatal thyrotoxicosis. (1000245)
1976
35
Congestive heart failure in neonatal thyrotoxicosis. A curable casue of heart failure in the newborn. (1192685)
1975
36
Neonatal thyrotoxicosis. (1134079)
1975
37
Persistent abnormalities in pituitary function following neonatal thyrotoxicosis in the rat. (4208653)
1974
38
Neonatal thyrotoxicosis treated with propranolol. (4429365)
1974
39
Propranolol in treatment of neonatal thyrotoxicosis. (4757519)
1973
40
Neonatal thyrotoxicosis. (4800423)
1973
41
The role of long acting thyroid stimulator in neonatal thyrotoxicosis. (4677121)
1972
42
Skeletal changes in neonatal thyrotoxicosis. (5008137)
1972
43
Neonatal thyrotoxicosis. Elevated long-acting thyroid stimulator (LATS) in mother and infant. (5762465)
1969
44
Neonatal thyrotoxicosis. (4185737)
1969
45
Neonatal thyrotoxicosis. (5645973)
1968
46
A case of neonatal thyrotoxicosis. (5588736)
1967
47
Neonatal thyrotoxicosis associated with maternal hypothyroidism. (4159675)
1966
48
Neonatal thyrotoxicosis: report of three cases involving four infants. (4168753)
1966
49
Survival time of circulating long-acting thyroid stimulator in neonatal thyrotoxicosis: implications for diagnosis and therapy of the disorder. (5846829)
1965
50
Neonatal thyrotoxicosis. (13731873)
1960

Variations for Neonatal Thyrotoxicosis

About this section

Expression for genes affiliated with Neonatal Thyrotoxicosis

About this section
Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Neonatal Thyrotoxicosis

Search GEO for disease gene expression data for Neonatal Thyrotoxicosis.

Pathways for genes affiliated with Neonatal Thyrotoxicosis

About this section

Compounds for genes affiliated with Neonatal Thyrotoxicosis

About this section
Sources:
45Novoseek, 24HMDB, 11DrugBank, 3BitterDB, 51PharmGKB, 29IUPHAR
See all sources

Compounds related to Neonatal Thyrotoxicosis according to GeneCards/GeneDecks:

(show all 19)
idCompoundScoreTop Affiliating Genes
1triiodothyronine459.7TXNRD2, TSHR
2asparagine459.6TSHR, TXNRD2
3cytosine45 2410.6TXNRD2, TSHR
4adenine45 24 1111.6TXNRD2, TSHR
5thyroxine45 2410.6TSHR, TXNRD2
6valine459.6TSHR, TXNRD2
7guanine45 24 1111.6TXNRD2, TSHR
8chloramphenicol45 3 51 1112.6TXNRD2, TSHR
9methionine459.5TXNRD2, TSHR
10proline459.5TSHR, TXNRD2
11hydrogen45 2410.5TSHR, TXNRD2
12thymidine45 2410.4TXNRD2, TSHR
13aspartate459.4TXNRD2, TSHR
14leucine459.3TSHR, TXNRD2
15phosphatidylinositol459.3TSHR, TXNRD2
16cholesterol45 29 24 1112.2TXNRD2, TSHR
17arginine459.0TSHR, TXNRD2
18cysteine458.8LHX3, TXNRD2, TSHR
19tyrosine458.7TSHR, TXNRD2, LHX3

GO Terms for genes affiliated with Neonatal Thyrotoxicosis

About this section

Products for genes affiliated with Neonatal Thyrotoxicosis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neonatal Thyrotoxicosis

About this section
4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet