MCID: NPH006
MIFTS: 29

Nephrogenic Adenofibroma malady

Cancer diseases, Nephrological diseases categories

Aliases & Classifications for Nephrogenic Adenofibroma

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Aliases & Descriptions for Nephrogenic Adenofibroma:

Name: Nephrogenic Adenofibroma 10 12 65
 
Metanephric Adenofibroma 10


Classifications:



External Ids:

Disease Ontology10 DOID:2698
SNOMED-CT59 128760004
NCIt42 C39812

Summaries for Nephrogenic Adenofibroma

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MalaCards based summary: Nephrogenic Adenofibroma, also known as metanephric adenofibroma, is related to renal cell carcinoma and adenofibroma. An important gene associated with Nephrogenic Adenofibroma is MAF (V-Maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Homolog), and among its related pathways are Transcriptional misregulation in cancer and C-MYB transcription factor network. Affiliated tissues include kidney, and related mouse phenotypes are renal/urinary system and embryogenesis.

Related Diseases for Nephrogenic Adenofibroma

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Diseases related to Nephrogenic Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 111)
idRelated DiseaseScoreTop Affiliating Genes
1renal cell carcinoma30.2CA9, KRT7, MME, PAX2, PAX8
2adenofibroma10.5
3fallopian tube disease10.3NCAM1, WT1
4endometriosis of intestine10.3PAX8, WT1
5papillary transitional carcinoma10.3PAX2, PAX8
6extrahepatic bile duct adenoma10.3MME, NCAM1
7esophageal atresia10.3MME, PAX2
8pulmonary plasma cell granuloma10.3B3GAT1, WT1
9hypoglycemia10.3KRT7, PAX8
10early invasive cervical adenocarcinoma10.3CALD1, MME
11ovary neuroendocrine neoplasm10.3KRT7, WT1
12glycogen storage disease due to lactate dehydrogenase deficiency10.3PAX2, WT1
13endocrine exophthalmos10.3MME, PAX8
14bladder calculus10.3KRT7, PAX8
15dyschromatosis universalis10.3KRT7, KRT8
16endomyocardial fibroelastosis10.3KRT7, KRT8
17radial hemimelia10.3PAX2, WT1
18gastroesophageal junction adenocarcinoma10.2PAX2, PAX8, WT1
19factor xiii deficiency10.2KRT7, KRT8
20breast apocrine carcinoma in situ10.2B3GAT1, NF1
21translocation renal cell carcinoma10.2KRT7, MME
22descending colon cancer10.2B3GAT1, MME
23uterine corpus adenomatoid tumor10.2CALD1, MME
24extrapulmonary tuberculosis10.2KRT7, KRT8
25peripartum cardiomyopathy10.2PAX2, PAX8
26acute laryngopharyngitis10.2MME, WT1
27schwachman diamond type metaphyseal dysplasia10.2MME, NCAM1, PAX2
28hemangioma of intra-abdominal structure10.2KRT8, PAX2, PAX8
29chromosomal disease10.2KRT7, MME
30ovary rhabdomyosarcoma10.2KRT8, MME, PAX2
31hepatorenal syndrome10.2KRT7, MME
32ethmoid sinus schneiderian papilloma10.2B3GAT1, CHL1, NCAM1
33benign pericardial teratoma10.2KRT7, PAX8, WT1
34fallopian tube squamous cell carcinoma10.2KRT7, PAX8, WT1
35monocular esotropia10.2KRT7, KRT8
36hypokalemia10.2MME, MYOG
37horner's syndrome10.2CALD1, MME, NCAM1
38trichostrongyloidiasis10.2KRT7, KRT8, WT1
39malignant peripheral nerve sheath tumor10.2KRT7, PAX8, WT1
40ovary sarcoma10.2KRT7, PAX8, WT1
41orbital cancer10.2MYOG, NF1
42anus leiomyosarcoma10.2CALD1, MYOG
43sternum lymphoma10.2KRT7, MME, NCAM1
44fibromatosis10.2KRT7, KRT8
45cystic kidney10.2KRT7, MME, NCAM1
46breast apocrine carcinoma10.2CALD1, MYOG
47pulmonary neuroendocrine tumor10.2CHL1, KRT7, NCAM1
48bile duct mucoepidermoid carcinoma10.1KRT7, KRT8, NF1
49cerebellar vermis medulloblastoma10.1KRT7, NCAM1, NF1
50schwannian stroma-rich and stroma-poor composite ganglioneuroblastoma10.1CALD1, KRT7, MME

Graphical network of the top 20 diseases related to Nephrogenic Adenofibroma:



Diseases related to nephrogenic adenofibroma

Symptoms for Nephrogenic Adenofibroma

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Drugs & Therapeutics for Nephrogenic Adenofibroma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Nephrogenic Adenofibroma

Genetic Tests for Nephrogenic Adenofibroma

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Anatomical Context for Nephrogenic Adenofibroma

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MalaCards organs/tissues related to Nephrogenic Adenofibroma:

33
Kidney

Animal Models for Nephrogenic Adenofibroma or affiliated genes

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MGI Mouse Phenotypes related to Nephrogenic Adenofibroma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053678.5CALD1, KRT7, MAF, NF1, PAX2, PAX8
2MP:00053808.2KRT8, MYOG, NF1, PAX2, PAX8, SS18
3MP:00053857.8KRT8, MYOD1, NF1, PAX2, PAX8, PDLIM5
4MP:00053787.0CALD1, KRT8, MAF, MYOD1, MYOG, NCAM1
5MP:00107685.7CA9, CALD1, KRT8, MAF, MYOD1, MYOG

Publications for Nephrogenic Adenofibroma

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Articles related to Nephrogenic Adenofibroma:

idTitleAuthorsYear
1
Nephrogenic adenofibroma in a young child. (11156329)
2000
2
Nephrogenic adenofibroma: an unusual renal tumor. (9112535)
1997
3
Nephrogenic adenofibroma. A novel kidney tumor of young people. (1373578)
1992

Variations for Nephrogenic Adenofibroma

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Expression for genes affiliated with Nephrogenic Adenofibroma

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Search GEO for disease gene expression data for Nephrogenic Adenofibroma.

Pathways for genes affiliated with Nephrogenic Adenofibroma

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Pathways related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4MAF, PAX8, SS18, WT1
28.8CD34, MAF, MYOD1
38.8MYOD1, MYOG, PAX2, PAX8

GO Terms for genes affiliated with Nephrogenic Adenofibroma

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Cellular components related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein-DNA complexGO:00329939.7MYOG, PAX2

Biological processes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1metanephric S-shaped body morphogenesisGO:007228410.7PAX8, WT1
2cellular response to gonadotropin stimulusGO:007137110.7PAX8, WT1
3pronephric field specificationGO:003900310.6PAX2, PAX8
4positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:007210810.6PAX2, PAX8
5metanephric nephron tubule formationGO:007228910.6PAX2, PAX8
6negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesisGO:007230510.6PAX2, PAX8
7negative regulation of apoptotic process involved in metanephric collecting duct developmentGO:190021510.6PAX2, PAX8
8negative regulation of apoptotic process involved in metanephric nephron tubule developmentGO:190021810.6PAX2, PAX8
9positive regulation of metanephric DCT cell differentiationGO:200059410.6PAX2, PAX8
10urogenital system developmentGO:000165510.6PAX2, PAX8
11metanephric mesenchyme developmentGO:007207510.6PAX2, WT1
12mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333710.6PAX2, PAX8
13positive regulation of branching involved in ureteric bud morphogenesisGO:009019010.6PAX2, PAX8
14regulation of metanephric nephron tubule epithelial cell differentiationGO:007230710.5PAX2, PAX8
15metanephric distal convoluted tubule developmentGO:007222110.4PAX2, PAX8
16pronephros developmentGO:004879310.4PAX2, PAX8
17mesenchymal to epithelial transitionGO:006023110.4PAX2, WT1
18negative regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021210.4PAX2, PAX8, WT1
19metanephric epithelium developmentGO:007220710.3PAX2, PAX8, WT1
20mesonephros developmentGO:000182310.2PAX2, PAX8, WT1
21branching involved in ureteric bud morphogenesisGO:000165810.1PAX2, PAX8, WT1
22metanephros developmentGO:000165610.1NF1, PAX8, WT1
23positive regulation of skeletal muscle fiber developmentGO:004874310.0MYOD1, MYOG
24muscle cell fate commitmentGO:00426939.9MYOD1, MYOG
25kidney developmentGO:00018229.9MME, PAX8, WT1
26myotube differentiationGO:00149029.9MYOD1, MYOG
27positive regulation of myoblast differentiationGO:00456639.9MYOD1, MYOG
28positive regulation of myoblast fusionGO:19017419.7MYOD1, MYOG
29myoblast differentiationGO:00454459.4MYOD1, MYOG
30skeletal muscle tissue developmentGO:00075198.9MYOD1, MYOG, NF1
31positive regulation of transcription, DNA-templatedGO:00458938.8MYOD1, MYOG, PAX2, PAX8, WT1
32transcription from RNA polymerase II promoterGO:00063668.6MAF, MYOD1, PAX2, PAX8, WT1
33positive regulation of transcription from RNA polymerase II promoterGO:00459447.9MAF, MYOD1, MYOG, PAX2, PAX8, SS18

Molecular functions related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific bindingGO:00012288.8MAF, MYOD1, MYOG
2sequence-specific DNA bindingGO:00435658.7MAF, MYOD1, MYOG, PAX8, WT1

Sources for Nephrogenic Adenofibroma

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet