MCID: NPH006
MIFTS: 29

Nephrogenic Adenofibroma malady

Categories: Nephrological diseases, Cancer diseases

Aliases & Classifications for Nephrogenic Adenofibroma

Aliases & Descriptions for Nephrogenic Adenofibroma:

Name: Nephrogenic Adenofibroma 12 14 69
Metanephric Adenofibroma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2698
NCIt 47 C39812
SNOMED-CT 64 128760004
UMLS 69 C1266141

Summaries for Nephrogenic Adenofibroma

MalaCards based summary : Nephrogenic Adenofibroma, also known as metanephric adenofibroma, is related to thymus lipoma and ovarian primitive germ cell tumor. An important gene associated with Nephrogenic Adenofibroma is MAF (MAF BZIP Transcription Factor), and among its related pathways/superpathways are Developmental Biology and Transcriptional misregulation in cancer. Affiliated tissues include kidney, and related phenotypes are Decreased sensitivity to paclitaxel and embryo

Related Diseases for Nephrogenic Adenofibroma

Diseases related to Nephrogenic Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 94)
id Related Disease Score Top Affiliating Genes
1 thymus lipoma 10.3 NCAM1 WT1
2 ovarian primitive germ cell tumor 10.3 PAX2 PAX8
3 occipital encephalocele 10.3 KRT18 KRT8
4 meninges hemangiopericytoma 10.3 PAX2 PAX8 WT1
5 connective tissue disease 10.3 NCAM1 PAX2 PAX8
6 childhood choriocarcinoma of the ovary 10.3 CALD1 MME
7 woolly hair, autosomal dominant 10.3 KRT18 KRT8
8 polycystic bone disease 10.3 MAF NCAM1
9 gallbladder cancer 10.3 MME PAX2 PAX8
10 trachea sarcoma 10.3 MME NCAM1 PAX2
11 lipoadenoma 10.2 KRT8 MME PAX2
12 uterine corpus myxoid leiomyosarcoma 10.2 B3GAT1 CHL1 NCAM1
13 vulvar alveolar soft part sarcoma 10.2 KRT18 KRT8 NCAM1
14 mixed type rhabdomyosarcoma 10.2 MYOD1 MYOG
15 envenomization by bothrops lanceolatus 10.2 KRT7 KRT8
16 kimura disease 10.2 KRT7 PAX2 PAX8
17 gastrointestinal neuroendocrine tumor 10.2 KRT7 PAX2 PAX8
18 conjunctival disease 10.2 MYOD1 WT1
19 uterine corpus endometrial stromal sarcoma 10.2 KRT7 PAX8 WT1
20 spinal canal intradural extramedullary neoplasm 10.2 CD34 MME
21 fuchs' heterochromic uveitis 10.2 KRT7 PAX8 WT1
22 skin amelanotic melanoma 10.2 KRT7 MME
23 cervical large cell neuroendocrine carcinoma 10.2 HBA1 WT1
24 cranial nerve disease 10.2 MME NCAM1 PAX2 PAX8
25 mucinous adenofibroma 10.2 B3GAT1 NCAM1 PAX2 WT1
26 subacute leukemia 10.2 MYOG NF1
27 non specific chronic endometritis 10.2 KRT7 NCAM1
28 brain stem infarction 10.2 MYOD1 MYOG WT1
29 postgastrectomy syndrome 10.2 B3GAT1 NF1
30 intrahepatic bile duct cystadenoma 10.2 MYOD1 NF1
31 cellular ependymoma 10.2 KRT7 MME NCAM1
32 spindle cell rhabdomyosarcoma 10.2 MYOD1 MYOG WT1
33 heart leiomyosarcoma 10.2 CALD1 MYOG
34 diabetes persistent mullerian ducts 10.2 MYOD1 MYOG WT1
35 proteus-like syndrome 10.1 KRT18 KRT7 KRT8
36 intracystic papillary adenoma 10.1 CD34 CHL1
37 rhabdomyosarcoma 2, alveolar 10.1 MYOD1 MYOG WT1
38 bartholin's gland adenoid cystic carcinoma 10.1 KRT18 KRT7 KRT8
39 vaginal villous adenoma 10.1 CHL1 KRT7 KRT8
40 fallopian tube mucinous tumor 10.1 CALD1 KRT7 MME
41 heart sarcoma 10.1 CALD1 MYOG
42 diffuse idiopathic skeletal hyperostosis 10.1 CALD1 KRT7 MME
43 acromegaly 10.1 B3GAT1 HBA1 MME
44 distal arthrogryposis 10.1 KRT18 KRT7 KRT8
45 malignant adult ependymoma 10.1 KRT18 KRT7 KRT8
46 kidney sarcoma 10.1 B3GAT1 MYOD1 MYOG
47 papillary serous adenocarcinoma 10.1 CD34 SS18
48 odontotrichoungual-digital-palmar syndrome 10.1 KRT7 KRT8 NCAM1
49 leiomyomatosis 10.1 CALD1 CD34
50 adenofibroma 10.1

Graphical network of the top 20 diseases related to Nephrogenic Adenofibroma:



Diseases related to Nephrogenic Adenofibroma

Symptoms & Phenotypes for Nephrogenic Adenofibroma

GenomeRNAi Phenotypes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased sensitivity to paclitaxel GR00112-A-0 8.62 NF1 WT1

MGI Mouse Phenotypes related to Nephrogenic Adenofibroma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.56 KRT18 KRT8 MYOG NF1 PAX2 PAX8
2 mortality/aging MP:0010768 9.44 WT1 CA9 KRT18 KRT8 MAF MYOD1

Drugs & Therapeutics for Nephrogenic Adenofibroma

Search Clinical Trials , NIH Clinical Center for Nephrogenic Adenofibroma

Genetic Tests for Nephrogenic Adenofibroma

Anatomical Context for Nephrogenic Adenofibroma

MalaCards organs/tissues related to Nephrogenic Adenofibroma:

39
Kidney

Publications for Nephrogenic Adenofibroma

Articles related to Nephrogenic Adenofibroma:

id Title Authors Year
1
Nephrogenic adenofibroma in a young child. ( 11156329 )
2000
2
Nephrogenic adenofibroma: an unusual renal tumor. ( 9112535 )
1997
3
Nephrogenic adenofibroma. A novel kidney tumor of young people. ( 1373578 )
1992

Variations for Nephrogenic Adenofibroma

Expression for Nephrogenic Adenofibroma

Search GEO for disease gene expression data for Nephrogenic Adenofibroma.

Pathways for Nephrogenic Adenofibroma

GO Terms for Nephrogenic Adenofibroma

Cellular components related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 9.13 KRT18 KRT7 KRT8
2 cell periphery GO:0071944 8.8 CD34 KRT18 KRT8

Biological processes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

(show all 27)
id Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.81 MME PAX8 WT1
2 skeletal muscle tissue development GO:0007519 9.7 MYOD1 MYOG NF1
3 branching involved in ureteric bud morphogenesis GO:0001658 9.67 PAX2 PAX8 WT1
4 urogenital system development GO:0001655 9.63 PAX2 PAX8
5 myotube differentiation GO:0014902 9.62 MYOD1 MYOG
6 hepatocyte apoptotic process GO:0097284 9.62 KRT18 KRT8
7 mesonephros development GO:0001823 9.61 PAX2 PAX8
8 mesenchymal to epithelial transition GO:0060231 9.61 PAX2 WT1
9 positive regulation of skeletal muscle fiber development GO:0048743 9.6 MYOD1 MYOG
10 cellular response to gonadotropin stimulus GO:0071371 9.59 PAX8 WT1
11 metanephric mesenchyme development GO:0072075 9.58 PAX2 WT1
12 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.58 PAX2 PAX8
13 muscle cell fate commitment GO:0042693 9.56 MYOD1 MYOG
14 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.55 PAX2 PAX8
15 pronephros development GO:0048793 9.54 PAX2 PAX8
16 metanephric S-shaped body morphogenesis GO:0072284 9.51 PAX8 WT1
17 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.48 PAX2 PAX8
18 metanephric nephron tubule formation GO:0072289 9.46 PAX2 PAX8
19 metanephric distal convoluted tubule development GO:0072221 9.43 PAX2 PAX8
20 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.4 PAX2 PAX8
21 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.37 PAX2 PAX8
22 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.32 PAX2 PAX8
23 positive regulation of metanephric DCT cell differentiation GO:2000594 9.26 PAX2 PAX8
24 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.16 PAX2 PAX8
25 pronephric field specification GO:0039003 8.96 PAX2 PAX8
26 metanephric epithelium development GO:0072207 8.8 PAX2 PAX8 WT1
27 positive regulation of transcription from RNA polymerase II promoter GO:0045944 10.11 MAF MYOD1 MYOG PAX2 PAX8 SS18

Sources for Nephrogenic Adenofibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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