Nephrogenic Adenofibroma malady

Categories: Nephrological diseases, Cancer diseases

Aliases & Classifications for Nephrogenic Adenofibroma

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Aliases & Descriptions for Nephrogenic Adenofibroma:

Name: Nephrogenic Adenofibroma 10 12 65
Metanephric Adenofibroma 10


External Ids:

Disease Ontology10 DOID:2698
SNOMED-CT59 128760004
NCIt42 C39812

Summaries for Nephrogenic Adenofibroma

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MalaCards based summary: Nephrogenic Adenofibroma, also known as metanephric adenofibroma, is related to fallopian tube adenosarcoma and plasmablastic lymphoma. An important gene associated with Nephrogenic Adenofibroma is MAF (V-Maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Homolog), and among its related pathways are Transcriptional misregulation in cancer and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include breast, liver and small intestine, and related mouse phenotypes are mortality/aging and homeostasis/metabolism.

Related Diseases for Nephrogenic Adenofibroma

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Diseases related to Nephrogenic Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1fallopian tube adenosarcoma10.8NCAM1, WT1
2plasmablastic lymphoma10.8MAF, NCAM1
3endometriosis of intestine10.8PAX8, WT1
4central nervous system endodermal sinus tumor10.8PAX2, PAX8
5pancreatic signet ring cell adenocarcinoma10.7MME, NCAM1
6pulmonary plasma cell granuloma10.7B3GAT1, WT1
7breast mucinous carcinoma10.7MME, PAX2
8complement component 3 deficiency10.7NF1, PAX8
9nephrogenic adenoma10.7KRT7, PAX8
10gastrointestinal system benign neoplasm10.7KRT7, PAX8
11congenital granular cell tumor10.7CALD1, MME
12peptic ulcer perforation10.6MME, PAX8
13breast cyst10.6B3GAT1, NCAM1
14methotrexate-associated lymphoproliferation10.6MME, PAX2
15ovarian papillary cystadenoma10.6B3GAT1, WT1
16transverse colon cancer10.6KRT8, MME
17lung adenoid cystic carcinoma10.6KRT7, KRT8
18follicular infundibulum tumor10.6B3GAT1, NF1
19adult mesoblastic nephroma10.6MME, WT1
20frontal sinus squamous cell carcinoma10.6B3GAT1, MME
21gastroesophageal junction adenocarcinoma10.6PAX2, PAX8, WT1
22radial hemimelia10.6PAX2, WT1
23malignant renovascular hypertension10.6CALD1, MME
24pediatric ovarian dysgerminoma10.5MME, PAX2, PAX8
25mucinous tubular and spindle renal cell carcinoma10.5KRT7, MME
26hepatorenal syndrome10.5KRT7, MME
27female breast upper-inner quadrant cancer10.5KRT7, MME
28posterior foramen magnum meningioma10.5B3GAT1, CHL1, NCAM1
29pancreatic cystadenoma10.5KRT7, NCAM1
30prostate malignant phyllodes tumor10.5KRT7, KRT8
31female reproductive organ cancer10.5MME, NCAM1, PAX2
32hilar cholangiocellular carcinoma10.5MME, PAX2, PAX8
33breast ductal carcinoma10.5KRT7, MME
34ophthalmoplegia10.5KRT8, MME, PAX2
35taylor's syndrome10.5KRT7, PAX8, WT1
36congenital structural myopathy10.5KRT7, PAX8, WT1
37spermatocytoma10.5MME, MYOG
38transitional cell carcinoma10.5KRT7, KRT8, WT1
39spastic ataxia 210.5PAX2, PAX8
40sarcomatoid mesothelioma10.5KRT7, WT1
41ischemia10.4MYOG, NF1
42conventional leiomyosarcoma10.4CALD1, MYOG
43central nervous system leiomyosarcoma10.4CALD1, MYOG
44urinary bladder villous adenoma10.4CALD1, MYOG
45cervical large cell neuroendocrine carcinoma10.4CHL1, KRT7, NCAM1
46fibrous synovial sarcoma10.4KRT7, MME, NCAM1
47perineurioma10.3KRT7, KRT8, NF1
48splenic infarction10.3KRT7, NCAM1, NF1
49childhood choroid plexus cancer10.3KRT7, KRT8
50cervical adenocarcinoma10.3CALD1, KRT7, MME

Graphical network of the top 20 diseases related to Nephrogenic Adenofibroma:

Diseases related to nephrogenic adenofibroma

Symptoms for Nephrogenic Adenofibroma

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Drugs & Therapeutics for Nephrogenic Adenofibroma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Nephrogenic Adenofibroma

Genetic Tests for Nephrogenic Adenofibroma

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Anatomical Context for Nephrogenic Adenofibroma

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MalaCards organs/tissues related to Nephrogenic Adenofibroma:

Breast, Liver, Small intestine, Lung, T cells, Myeloid, Testis

Animal Models for Nephrogenic Adenofibroma or affiliated genes

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MGI Mouse Phenotypes related to Nephrogenic Adenofibroma:

idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107686.3CA9, KRT8, MAF, MYOD1, MYOG, NCAM1
2MP:00053765.8CD34, KRT7, KRT8, MAF, MME, MYOD1

Publications for Nephrogenic Adenofibroma

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Articles related to Nephrogenic Adenofibroma:

Nephrogenic adenofibroma in a young child. (11156329)
Nephrogenic adenofibroma: an unusual renal tumor. (9112535)
Nephrogenic adenofibroma. A novel kidney tumor of young people. (1373578)

Variations for Nephrogenic Adenofibroma

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Expression for genes affiliated with Nephrogenic Adenofibroma

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Search GEO for disease gene expression data for Nephrogenic Adenofibroma.

Pathways for genes affiliated with Nephrogenic Adenofibroma

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GO Terms for genes affiliated with Nephrogenic Adenofibroma

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Cellular components related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:00450959.8KRT7, KRT8

Biological processes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1metanephric S-shaped body morphogenesisGO:007228410.7PAX8, WT1
2positive regulation of metanephric DCT cell differentiationGO:200059410.6PAX2, PAX8
3negative regulation of apoptotic process involved in metanephric collecting duct developmentGO:190021510.6PAX2, PAX8
4pronephric field specificationGO:003900310.6PAX2, PAX8
5positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:007210810.6PAX2, PAX8
6metanephric distal convoluted tubule developmentGO:007222110.6PAX2, PAX8
7negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesisGO:007230510.6PAX2, PAX8
8cellular response to gonadotropin stimulusGO:007137110.6PAX8, WT1
9positive regulation of branching involved in ureteric bud morphogenesisGO:009019010.6PAX2, PAX8
10mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333710.6PAX2, PAX8
11metanephric mesenchyme developmentGO:007207510.5PAX2, WT1
12urogenital system developmentGO:000165510.4PAX2, PAX8
13cognitionGO:005089010.4CHL1, NF1
14metanephric epithelium developmentGO:007220710.2PAX2, PAX8, WT1
15metanephros developmentGO:000165610.2NF1, PAX8
16kidney developmentGO:000182210.1MME, PAX8, WT1
17adrenal gland developmentGO:00303259.9NF1, WT1
18positive regulation of muscle cell differentiationGO:00511499.9MYOD1, MYOG
19positive regulation of myoblast fusionGO:19017419.9MYOD1, MYOG
20myotube differentiationGO:00149029.9MYOD1, MYOG
21skeletal muscle fiber developmentGO:00487419.8MYOD1, MYOG
22skeletal muscle tissue developmentGO:00075199.3MYOD1, MYOG, NF1
23regulation of transcription, DNA-templatedGO:00063558.4MAF, MYOD1, MYOG, PAX2, PAX8, WT1
24positive regulation of transcription from RNA polymerase II promoterGO:00459447.8MYOD1, MYOG, PAX2, PAX8, SS18, WT1

Molecular functions related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription factor activity, sequence-specific DNA bindingGO:00037009.1MAF, MYOD1, MYOG

Sources for Nephrogenic Adenofibroma

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28ICD10 via Orphanet
37MESH via Orphanet
50OMIM via Orphanet
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
66UMLS via Orphanet