MCID: NPH006
MIFTS: 28

Nephrogenic Adenofibroma malady

Categories: Nephrological diseases, Cancer diseases

Aliases & Classifications for Nephrogenic Adenofibroma

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Aliases & Descriptions for Nephrogenic Adenofibroma:

Name: Nephrogenic Adenofibroma 11 13 68
 
Metanephric Adenofibroma 11

Classifications:



External Ids:

Disease Ontology11 DOID:2698
SNOMED-CT62 128760004
NCIt45 C39812

Summaries for Nephrogenic Adenofibroma

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MalaCards based summary: Nephrogenic Adenofibroma, also known as metanephric adenofibroma, is related to thymus lipoma and ovarian primitive germ cell tumor. An important gene associated with Nephrogenic Adenofibroma is MAF (MAF BZIP Transcription Factor), and among its related pathways are ID signaling pathway and Primary Focal Segmental Glomerulosclerosis FSGS. Affiliated tissues include kidney, and related mouse phenotypes are Decreased sensitivity to paclitaxel and embryo.

Related Diseases for Nephrogenic Adenofibroma

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Diseases related to Nephrogenic Adenofibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1thymus lipoma10.3NCAM1, WT1
2ovarian primitive germ cell tumor10.3PAX2, PAX8
3occipital encephalocele10.3KRT18, KRT8
4meninges hemangiopericytoma10.3PAX2, PAX8, WT1
5connective tissue disease10.3NCAM1, PAX2, PAX8
6childhood choriocarcinoma of the ovary10.3CALD1, MME
7woolly hair, autosomal dominant10.3KRT18, KRT8
8polycystic bone disease10.3MAF, NCAM1
9gallbladder cancer10.3MME, PAX2, PAX8
10trachea sarcoma10.3MME, NCAM1, PAX2
11lipoadenoma10.2KRT8, MME, PAX2
12uterine corpus myxoid leiomyosarcoma10.2B3GAT1, CHL1, NCAM1
13vulvar alveolar soft part sarcoma10.2KRT18, KRT8, NCAM1
14mixed type rhabdomyosarcoma10.2MYOD1, MYOG
15envenomization by bothrops lanceolatus10.2KRT7, KRT8
16kimura disease10.2KRT7, PAX2, PAX8
17gastrointestinal neuroendocrine tumor10.2KRT7, PAX2, PAX8
18conjunctival disease10.2MYOD1, WT1
19uterine corpus endometrial stromal sarcoma10.2KRT7, PAX8, WT1
20spinal canal intradural extramedullary neoplasm10.2CD34, MME
21fuchs' heterochromic uveitis10.2KRT7, PAX8, WT1
22skin amelanotic melanoma10.2KRT7, MME
23cervical large cell neuroendocrine carcinoma10.2HBA1, WT1
24cranial nerve disease10.2MME, NCAM1, PAX2, PAX8
25mucinous adenofibroma10.2B3GAT1, NCAM1, PAX2, WT1
26subacute leukemia10.2MYOG, NF1
27non specific chronic endometritis10.2KRT7, NCAM1
28brain stem infarction10.2MYOD1, MYOG, WT1
29postgastrectomy syndrome10.2B3GAT1, NF1
30intrahepatic bile duct cystadenoma10.2MYOD1, NF1
31cellular ependymoma10.2KRT7, MME, NCAM1
32spindle cell rhabdomyosarcoma10.2MYOD1, MYOG, WT1
33heart leiomyosarcoma10.2CALD1, MYOG
34diabetes persistent mullerian ducts10.2MYOD1, MYOG, WT1
35proteus-like syndrome10.1KRT18, KRT7, KRT8
36intracystic papillary adenoma10.1CD34, CHL1
37rhabdomyosarcoma 2, alveolar10.1MYOD1, MYOG, WT1
38bartholin's gland adenoid cystic carcinoma10.1KRT18, KRT7, KRT8
39vaginal villous adenoma10.1CHL1, KRT7, KRT8
40fallopian tube mucinous tumor10.1CALD1, KRT7, MME
41heart sarcoma10.1CALD1, MYOG
42diffuse idiopathic skeletal hyperostosis10.1CALD1, KRT7, MME
43acromegaly10.1B3GAT1, HBA1, MME
44distal arthrogryposis10.1KRT18, KRT7, KRT8
45malignant adult ependymoma10.1KRT18, KRT7, KRT8
46kidney sarcoma10.1B3GAT1, MYOD1, MYOG
47papillary serous adenocarcinoma10.1CD34, SS18
48odontotrichoungual-digital-palmar syndrome10.1KRT7, KRT8, NCAM1
49leiomyomatosis10.1CALD1, CD34
50adenofibroma10.1

Graphical network of the top 20 diseases related to Nephrogenic Adenofibroma:



Diseases related to nephrogenic adenofibroma

Symptoms & Phenotypes for Nephrogenic Adenofibroma

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GenomeRNAi Phenotypes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00112-A-010.7NF1, WT1

MGI Mouse Phenotypes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053808.7KRT18, KRT8, MYOG, NF1, PAX2, PAX8
2MP:00107686.5CA9, KRT18, KRT8, MAF, MYOD1, MYOG

Drugs & Therapeutics for Nephrogenic Adenofibroma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Nephrogenic Adenofibroma

Genetic Tests for Nephrogenic Adenofibroma

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Anatomical Context for Nephrogenic Adenofibroma

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MalaCards organs/tissues related to Nephrogenic Adenofibroma:

36
Kidney

Publications for Nephrogenic Adenofibroma

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Articles related to Nephrogenic Adenofibroma:

idTitleAuthorsYear
1
Nephrogenic adenofibroma in a young child. (11156329)
2000
2
Nephrogenic adenofibroma: an unusual renal tumor. (9112535)
1997
3
Nephrogenic adenofibroma. A novel kidney tumor of young people. (1373578)
1992

Variations for Nephrogenic Adenofibroma

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Expression for genes affiliated with Nephrogenic Adenofibroma

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Search GEO for disease gene expression data for Nephrogenic Adenofibroma.

Pathways for genes affiliated with Nephrogenic Adenofibroma

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GO Terms for genes affiliated with Nephrogenic Adenofibroma

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Cellular components related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell peripheryGO:00719449.6CD34, KRT18, KRT8
2keratin filamentGO:00450959.4KRT18, KRT7, KRT8

Biological processes related to Nephrogenic Adenofibroma according to GeneCards Suite gene sharing:

(show all 27)
idNameGO IDScoreTop Affiliating Genes
1mesenchymal to epithelial transitionGO:006023110.8PAX2, WT1
2metanephric mesenchyme developmentGO:007207510.8PAX2, WT1
3cellular response to gonadotropin stimulusGO:007137110.8PAX8, WT1
4metanephric S-shaped body morphogenesisGO:007228410.8PAX8, WT1
5mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333710.7PAX2, PAX8
6mesonephros developmentGO:000182310.7PAX2, PAX8
7metanephric distal convoluted tubule developmentGO:007222110.7PAX2, PAX8
8metanephric nephron tubule formationGO:007228910.7PAX2, PAX8
9negative regulation of apoptotic process involved in metanephric collecting duct developmentGO:190021510.7PAX2, PAX8
10negative regulation of apoptotic process involved in metanephric nephron tubule developmentGO:190021810.7PAX2, PAX8
11negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesisGO:007230510.7PAX2, PAX8
12negative regulation of mesenchymal cell apoptotic process involved in metanephros developmentGO:190021210.7PAX2, PAX8
13positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesisGO:007210810.7PAX2, PAX8
14positive regulation of metanephric DCT cell differentiationGO:200059410.7PAX2, PAX8
15hepatocyte apoptotic processGO:009728410.6KRT18, KRT8
16branching involved in ureteric bud morphogenesisGO:000165810.5PAX2, PAX8, WT1
17metanephric epithelium developmentGO:007220710.5PAX2, PAX8, WT1
18pronephric field specificationGO:003900310.5PAX2, PAX8
19pronephros developmentGO:004879310.5PAX2, PAX8
20regulation of metanephric nephron tubule epithelial cell differentiationGO:007230710.5PAX2, PAX8
21kidney developmentGO:000182210.5MME, PAX8, WT1
22muscle cell fate commitmentGO:004269310.3MYOD1, MYOG
23myotube differentiationGO:001490210.3MYOD1, MYOG
24positive regulation of skeletal muscle fiber developmentGO:004874310.3MYOD1, MYOG
25urogenital system developmentGO:000165510.0PAX2, PAX8
26skeletal muscle tissue developmentGO:00075199.6MYOD1, MYOG, NF1
27positive regulation of transcription from RNA polymerase II promoterGO:00459448.9MAF, MYOD1, MYOG, PAX2, PAX8, SS18

Sources for Nephrogenic Adenofibroma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet