MCID: NPH010
MIFTS: 44

Nephrosclerosis malady

Categories: Rare diseases, Cardiovascular diseases, Nephrological diseases

Aliases & Classifications for Nephrosclerosis

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Aliases & Descriptions for Nephrosclerosis:

Name: Nephrosclerosis 11 46 13 25 48 37 66
 
Renal Sclerosis 11

Classifications:



External Ids:

Disease Ontology11 DOID:11664
ICD1028 I12, N26.9
ICD9CM30 587
MeSH37 D009400

Summaries for Nephrosclerosis

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Wikipedia:69 Hypertensive nephropathy (or \"hypertensive nephrosclerosis\", or \"Hypertensive kidney disease\") is a... more...

MalaCards based summary: Nephrosclerosis, also known as renal sclerosis, is related to respiratory syncytial virus infectious disease and intracranial chondrosarcoma. An important gene associated with Nephrosclerosis is ACE (Angiotensin I Converting Enzyme), and among its related pathways are Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics and Sympathetic Nerve Pathway (Neuroeffector Junction). Affiliated tissues include kidney, pituitary and heart, and related mouse phenotypes are adipose tissue and renal/urinary system.

Related Diseases for Nephrosclerosis

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Diseases related to Nephrosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 123)
idRelated DiseaseScoreTop Affiliating Genes
1respiratory syncytial virus infectious disease10.6ACE, MTHFR
2intracranial chondrosarcoma10.6ADRB1, ADRB2
3fatal infantile hypertrophic cardiomyopathy due to mitochondrial complex i deficiency10.6ACE, TGFB1
4ovarian cancer10.6ACE, AGTR1
5casr-related disorders10.6ACE, AGTR1
6antiphospholipid syndrome10.5ACE, AGTR1
7chylocele of tunica vaginalis10.5ACE, AGTR1
8islet cell tumor10.5ACE, MTHFR
9hepatocellular adenoma10.5ACE, MTHFR
10congenital methemoglobinemia10.5AGTR1, TGFB1
11burns10.5ACE, TGFB1
12broad ligament malignant neoplasm10.4ACE, ADRB1, AGTR1
13aphthous stomatitis10.4ACE, ADRB1
14joint disorders10.4ACE, AGTR1, MTHFR
15alpha-2-plasmin inhibitor deficiency10.4ACE, AGTR1, MTHFR
16acute myeloblastic leukemia without maturation10.4ACE, ADRB2, AGTR1
17podder-tolmie syndrome10.4ADRB1, ADRB2, AGTR1
18fibula aplasia complex brachydactyly10.3ACE, AGTR1, TGFB1
19post-infectious myocarditis10.3ACE, AGTR1, TGFB1
20poikiloderma with neutropenia10.3ADRB1, ADRB2, AGTR1
21littre gland carcinoma10.3ACE, AGTR1, MTHFR
22histoplasmosis10.3CCL2, MTHFR
23vibrio vulnificus infection10.3CCL2, TGFB1
24kidney hypertrophy10.3ACE, AGTR1, TGFB1
25stroke, ischemic10.3ACE, AGTR1, MTHFR
26lymphogranuloma venereum10.3CTGF, TGFB1
27prediabetes syndrome10.2CCL2, MTHFR
28renal dysplasia, bilateral10.2CTGF, SYNPO
29suppurative uveitis10.2CCL2, SYNPO
30hypohidrosis10.2CTGF, TGFB1
31opportunistic mycosis10.2ACE, CCL2, MTHFR
32lung hilum cancer10.2ACE, CCL2, MTHFR
33acromicric dysplasia10.2CTGF, TGFB1
34twin-to-twin transfusion syndrome10.2CCL2, TGFB1
35sinusitis10.1ACE, CCL2, TGFB1
36benign hypertensive renal disease10.1ACE, AGTR1
37aortic valves stenosis of the child10.1ACE, ADRB1, ADRB2, AGTR1
38craniosynostosis10.1ACE, ADRB1, ADRB2, AGTR1
39glomerulonephritis10.1
40basaloid squamous cell carcinoma10.1ACE, CCL2, TGFB1
41irritable bowel syndrome10.1ACE, AGTR1, CTGF
42kidney disease10.1
43fundus dystrophy10.1ACE, CCL2, TGFB1
44hypertension, essential10.1ACE, ADRB1, ADRB2, AGTR1
45hemolytic-uremic syndrome10.0
46vitreous abscess10.0CTGF, TGFB1
47citrullinemia, adult-onset type ii10.0ACE, AGTR1, CTGF
48temporomandibular ankylosis10.0ACE, CTGF, TGFB1
49malignant hypertension10.0
50pyelonephritis10.0

Comorbidity relations with Nephrosclerosis via Phenotypic Disease Network (PDN):


Acute Kidney FailureChronic Kidney Failure
Deficiency AnemiaHeart Disease
Hypertension, EssentialIschemic Heart Disease
Acute CystitisHydronephrosis
NephrolithiasisPrimary Hyperoxaluria

Graphical network of the top 20 diseases related to Nephrosclerosis:



Diseases related to nephrosclerosis

Symptoms for Nephrosclerosis

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Drugs & Therapeutics for Nephrosclerosis

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Drugs for Nephrosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
angiotensin IIPhase 4113568521-88-0, 11128-99-7172198, 65143
Synonyms:
1-8-Angiotensin I
1-L-Aspasaginyl-5-L-valyl angiotensin octapeptide
Ang II
Angiotensin 2
Angiotensin II (human)
 
Angiotensin II (mouse)
Angiotonin
Asp-arg-val-TYR-ile-his-pro-phe
Human angiotensin II
Hypertensin
Ile(5)-angiotensin II
2
ValsartanPhase 4280137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
 
Kalpress
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
3TEZOSENTANPhase 2, Phase 365
4BeraprostPhase 2, Phase 31588430-50-6
5
EpoprostenolPhase 2, Phase 35361849-14-7, 35121-78-95280427, 5282411
Synonyms:
(5E)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3R)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
(5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
(5Z)-5-[(4R,5R)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
(5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
(5Z,13E)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E,15S)-6,9a-epoxy-11a,15-dihydroxyprosta-5,13-dienoate
(5Z,13E,15S)-6,9a-epoxy-11a,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13E,15S)-6,9alpha-epoxy-11alpha,15-dihydroxyprosta-5,13-dienoic acid
(5Z,13e)-(15S)-6,9alpha-Epoxy-11alpha,15-dihydroxyprosta-5,13-dienoate
(5Z,9a,11a,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oate
(5Z,9a,11a,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
(5Z,9alpha,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprosta-5,13-dien-1-oic acid
(5Z,9alpha,11alpha,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oate
(5Z,9alpha,11alpha,13E,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
(5Z,9alpha,11alpha,13e,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic acid
(Z)-(3aR,4R,5R,6aS)-Hexahydro-5-hydroxy-4-((E)-(3S)-3-hydroxy-1-octenyl)-2H-cyclopenta(b)furan-delta(sup 2,delta)-valeric acid
136626-78-3
35121-78-9
5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
5-[5-hydroxy-4-(3-hydroxyoct-1-enyl)-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-2-ylidene]pentanoic acid
6,9-alpha-Epoxy-11-alpha,15(S)-dihydroxyprosta-5(Z),13(E)-dien-1-oic acid
61849-14-7
63748-50-5
63859-31-4
AC1L18LX
AC1L3FZB
AC1NQX0K
AC1NR00P
AC1O51WG
AC1O5HI7
AR-1I7150
BIDD:GT0514
BRD-K64054020-001-02-7
BRN 1690090
BSPBio_001496
Bio2_000216
Bio2_000696
C01312
CHEBI:15552
CHEMBL1139
CHEMBL307845
CID114805
CID11969614
CID159
CID5280427
CID5282411
CID6434194
CID6450541
 
CID9864371
CID9975312
D00106
DB01240
Epoprostanol
Epoprostenol
Epoprostenol (TN)
Epoprostenol (USAN/INN)
Epoprostenol [USAN:INN]
Epoprostenolum
Epoprostenolum [INN-Latin]
Flolan
HMS1791K18
HMS1989K18
IDI1_033966
KB-IV-24
KBio2_000216
KBio2_002784
KBio2_005352
KBio3_000431
KBio3_000432
KBioGR_000216
KBioSS_000216
LMFA03010087
LS-125828
NCGC00161285-01
NCGC00161285-02
NCGC00161285-03
PDSP1_001721
PDSP2_001704
PG-I2
PGI(sub 2)
PGI2
PGX
Prostacyclin
Prostacyclin I2
Prostacycline
Prostacyclins
Prostaglandin I
Prostaglandin I(2)
Prostaglandin I2
Prostaglandin X
Prostaglandin x
Prostaglandins X
SMP2_000227
TRY 200
Try-200
U 53,217
U-53217
UNII-DCR9Z582X0
Vasocyclin
epoprostenol
prostacyclin
prostaglandin I2

Interventional clinical trials:

idNameStatusNCT IDPhase
1Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney DiseaseTerminatedNCT01129557Phase 4
2TRK-100STP Clinical Study - Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis)CompletedNCT01090037Phase 2, Phase 3
3TRK-100STP PhaseII Clinical Study -Chronic Renal Failure (Primary Glomerular Disease/Nephrosclerosis)CompletedNCT02480751Phase 2
4Renal NCE-MRI in Healthy VolunteersCompletedNCT02618460

Search NIH Clinical Center for Nephrosclerosis


Cochrane evidence based reviews: nephrosclerosis

Genetic Tests for Nephrosclerosis

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Genetic tests related to Nephrosclerosis:

id Genetic test Affiliating Genes
1 Nephrosclerosis25

Anatomical Context for Nephrosclerosis

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MalaCards organs/tissues related to Nephrosclerosis:

34
Kidney, Pituitary, Heart, Pancreas, Bone, Smooth muscle, Endothelial

Animal Models for Nephrosclerosis or affiliated genes

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MGI Mouse Phenotypes related to Nephrosclerosis:

39
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053758.9ACE, ADRB1, ADRB2, AGTR1, TGFB1
2MP:00053677.4ACE, AGTR1, BMP5, NPHS1, NPHS2, SYNPO
3MP:00053857.2ACE, ADRB1, ADRB2, AGTR1, BMP5, CTGF
4MP:00107686.5ACE, ADRB1, AGTR1, BMP5, CTGF, MTHFR
5MP:00053786.5ACE, ADRB1, ADRB2, AGTR1, BMP5, CTGF
6MP:00053766.3ACE, ADRB1, ADRB2, AGTR1, CTGF, MTHFR

Publications for Nephrosclerosis

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Articles related to Nephrosclerosis:

(show top 50)    (show all 267)
idTitleAuthorsYear
1
Serum potassium predicts time to blood pressure response among African Americans with hypertensive nephrosclerosis. (23151750)
2013
2
Prevalence and risk factor analysis of nephrosclerosis and ischemic nephropathy in the Japanese general population. (23832327)
2013
3
Hypertensive nephrosclerosis in Kenya. (22179094)
2011
4
Senile nephrosclerosis--does it explain the decline in glomerular filtration rate with aging? (21832860)
2011
5
Bone morphogenetic protein (BMP)-7 expression is decreased in human hypertensive nephrosclerosis. (21080950)
2010
6
Human nephrosclerosis triggers a hypoxia-related glomerulopathy. (20019191)
2010
7
Hypertensive nephrosclerosis. (18408477)
2008
8
Combination therapy with telmisartan and spironolactone alleviates L-NAME exacerbated nephrosclerosis with an increase in PPAR-gamma and decrease in TGF-beta(1). (17998773)
2007
9
Functional polymorphism of the myeloperoxidase gene in hypertensive nephrosclerosis dialysis patients. (18344624)
2007
10
Hypertensive nephrosclerosis. (16988752)
2006
11
Dr. Yang Nizhi's experience in treating benign arteriolar nephrosclerosis. (16705856)
2006
12
Hypertensive nephrosclerosis: update. (15202608)
2004
13
A 3-hydroxy-3-methylglutaryl co-enzyme A reductase inhibitor reduces hypertensive nephrosclerosis in stroke-prone spontaneously hypertensive rats. (12473872)
2002
14
Intrauterine food restriction as a determinant of nephrosclerosis. (11228169)
2001
15
Cilnidipine is as effective as benazepril for control of blood pressure and proteinuria in hypertensive patients with benign nephrosclerosis. (11510750)
2001
16
Clinical trials report. The effect of Ramipril versus Amlodipine on renal outcomes in hypertension nephrosclerosis. (11551370)
2001
17
ACE inhibitors and appearance of renal events in hypertensive nephrosclerosis. (11566948)
2001
18
Hypertensive nephrosclerosis as a relevant cause of chronic renal failure. (11509471)
2001
19
Hypertensive nephrosclerosis-a cause of end-stage renal disease? (11007815)
2000
20
Hypertensive nephrosclerosis pathogenesis, diagnosis and management. (18212435)
1999
21
Progression of renal failure and hypertensive nephrosclerosis. (9839285)
1998
22
Antihypertensive agents prevent nephrosclerosis and left ventricular hypertrophy induced in rats by prolonged inhibition of nitric oxide synthesis. (9657629)
1998
23
Evaluation of serum creatinine for estimating glomerular filtration rate in African Americans with hypertensive nephrosclerosis: results from the African-American Study of Kidney Disease and Hypertension (AASK) Pilot Study. (9048347)
1997
24
Possible relationship between hyperinsulinemia and glomerular hypertrophy in nephrosclerosis. (8723365)
1996
25
Effects of novel, nonpeptide vasopressin antagonists on progressive nephrosclerosis in rats. (7630164)
1995
26
Can we accurately diagnose nephrosclerosis? (8524488)
1995
27
Hypertensive nephrosclerosis in the Dahl/Rapp rat. Initial sites of injury and effect of dietary L-arginine supplementation. (8441251)
1993
28
Clinical features of benign hypertensive nephrosclerosis at time of renal biopsy. (8327642)
1993
29
Hyperfiltration and conservation of renal function in hypertensive nephrosclerosis patients. (8465839)
1993
30
Reversible renal insufficiency due to angiotensin converting enzyme inhibitors in hypertensive nephrosclerosis. (1883120)
1991
31
Long-term improvement in renal function after short-term strict blood pressure control in hypertensive nephrosclerosis. (2544523)
1989
32
Long-term survival after recovery from malignant nephrosclerosis. (3370137)
1988
33
Quantitation of hypertensive nephrosclerosis on an objective rational scale of measure in adults and children. (3751980)
1986
34
Marked proteinuria in hypertensive nephrosclerosis. (3160240)
1985
35
Effect of castration on the experimental renal hypertension of the rat. Blood pressure, nephrosclerosis, long-chain fatty acids, and N-acetylation of PAH in the kidney. (4000342)
1985
36
Glomerular injury in malignant nephrosclerosis. (740104)
1978
37
Pathology of malignant nephrosclerosis with special reference to the difference between histologic manifestations of pure and exacerbated forms. (694919)
1978
38
An accelerated hypertension with neither malignant nephrosclerosis nor elevation of plasma renin activity. (650894)
1978
39
Malignant nephrosclerosis in patients with hemolytic uremic syndrome (primary malignant nephrosclerosis). (913126)
1977
40
Nephrosclerosis and blood pressure. II. Reversibility of proliferative arteriosclerosis. (4130305)
1974
41
Effect of bilateral nephrectomy in postpartum nephrosclerosis. (5093216)
1971
42
Radiation hypertension and nephrosclerosis. (5409700)
1970
43
IMMUNOCYTOCHEMICAL OBSERVATIONS ON THE VASCULAR NECROSIS AND RENAL GLOMERULAR LESIONS OF MALIGNANT NEPHROSCLEROSIS. (14328020)
1965
44
MALIGNANT HYPERTENSION, MALIGNANT NEPHROSCLEROSIS, AND SYSTEMIC VASCULITIS. (14303079)
1965
45
Uremia and disseminated platelet-cell (thrombocyte) thrombosis; report of a case due to malignant nephrosclerosis with acute pancreatitis. (14914218)
1952
46
VA clinical pathological conference: cerebral hemorrhage associated with malignant nephrosclerosis and cardiac hypertrophy. (13013101)
1952
47
Clinical pathologic conference; hypertension, malignant phase, characterized by cardiac hypertrophy, marked, predominantly left ventricle; hyperplastic arteriosclerosis and malignant nephrosclerosis. (14779219)
1950
48
Malignant nephrosclerosis in pregnancy. (18135965)
1949
49
On the pathogenesis of red essential arterial hypertension and of malignant nephrosclerosis. (18857649)
1948
50
Nephrosclerosis]. (20271308)
1947

Variations for Nephrosclerosis

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Expression for genes affiliated with Nephrosclerosis

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Search GEO for disease gene expression data for Nephrosclerosis.

Pathways for genes affiliated with Nephrosclerosis

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GO Terms for genes affiliated with Nephrosclerosis

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Cellular components related to Nephrosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1slit diaphragmGO:00360579.0NPHS1, NPHS2

Biological processes related to Nephrosclerosis according to GeneCards Suite gene sharing:

(show all 22)
idNameGO IDScoreTop Affiliating Genes
1regulation of systemic arterial blood pressure by renin-angiotensinGO:000308110.6ACE, AGTR1
2mononuclear cell proliferationGO:003294310.5ACE, TGFB1
3regulation of vasodilationGO:004231210.5ACE, AGTR1
4positive regulation of cellular protein metabolic processGO:003227010.3AGTR1, TGFB1
5heat generationGO:003164910.3ADRB1, ADRB2
6vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressureGO:000202510.3ADRB1, ADRB2
7lipopolysaccharide-mediated signaling pathwayGO:003166310.3CCL2, TGFB1
8negative regulation of multicellular organism growthGO:004001510.2ADRB1, ADRB2
9negative regulation of ossificationGO:003027910.1ADRB2, TGFB1
10brown fat cell differentiationGO:005087310.1ADRB1, ADRB2
11diet induced thermogenesisGO:000202410.1ADRB1, ADRB2
12cellular response to dexamethasone stimulusGO:007154910.0CCL2, TGFB1
13regulation of vasoconstrictionGO:00192299.9ACE, AGTR1
14negative regulation of gene expressionGO:00106299.7ACE, CTGF, TGFB1
15positive regulation of collagen biosynthetic processGO:00329679.6CCL2, CTGF, TGFB1
16response to woundingGO:00096119.6CCL2, CTGF, TGFB1
17regulation of sodium ion transportGO:00020289.6ADRB2, TGFB1
18response to progesteroneGO:00325709.4ADRB2, CCL2, TGFB1
19response to hypoxiaGO:00016669.3CCL2, MTHFR, TGFB1
20adenylate cyclase-activating adrenergic receptor signaling pathwayGO:00718809.3ADRB1, ADRB2
21response to amino acidGO:00432009.2CCL2, CTGF, MTHFR
22agingGO:00075689.0ADRB2, CCL2, CTGF, TGFB1

Molecular functions related to Nephrosclerosis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1bradykinin receptor bindingGO:003171110.5ACE, AGTR1
2norepinephrine bindingGO:005138010.2ADRB1, ADRB2
3epinephrine bindingGO:005137910.2ADRB1, ADRB2
4growth factor activityGO:00080839.3BMP5, CTGF, TGFB1
5cytokine activityGO:00051259.1BMP5, CCL2, TGFB1

Sources for Nephrosclerosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet