MCID: NRV004
MIFTS: 27

Nerve Compression Syndrome malady

Neuronal diseases category

Aliases & Classifications for Nerve Compression Syndrome

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Nerve Compression Syndrome, Aliases & Descriptions:

Name: Nerve Compression Syndrome 9 11 60
Entrapment Neuropathies 43 60
Hereditary Liability to Pressure Palsies 60
 
Peripheral Nerve Entrapment Syndrome 9
Compression Neuropathy 9
Entrapment Neuropathy 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:573
SNOMED-CT55 45781009, 155085004
MeSH33 D009408

Summaries for Nerve Compression Syndrome

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Wikipedia:63 Nerve compression syndrome or compression neuropathy, also known as entrapment neuropathy, is a medical... more...

MalaCards based summary: Nerve Compression Syndrome, also known as entrapment neuropathies, is related to neuropathy and hereditary neuropathy with liability to pressure palsy, and has symptoms including abnormality of the motor neuronsand motor conduction block. An important gene associated with Nerve Compression Syndrome is PMP22 (peripheral myelin protein 22), and among its related pathways is Neural Crest Differentiation. The compounds serine and aspartate have been mentioned in the context of this disorder. Related mouse phenotypes are muscle and hearing/vestibular/ear.

Related Diseases for Nerve Compression Syndrome

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Graphical network of the top 20 diseases related to Nerve Compression Syndrome:



Diseases related to nerve compression syndrome

Symptoms for Nerve Compression Syndrome

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HPO human phenotypes related to Nerve Compression Syndrome:

id Description Frequency HPO Source Accession
1 abnormality of the motor neurons HP:0002450
2 motor conduction block HP:0012078

Drugs & Therapeutics for Nerve Compression Syndrome

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Drug clinical trials:

Search ClinicalTrials for Nerve Compression Syndrome

Search NIH Clinical Center for Nerve Compression Syndrome

Genetic Tests for Nerve Compression Syndrome

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Anatomical Context for Nerve Compression Syndrome

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Animal Models for Nerve Compression Syndrome or affiliated genes

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MGI Mouse Phenotypes related to Nerve Compression Syndrome:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053699.1NOTCH1, PMP22
2MP:00053779.0NOTCH1, PMP22
3MP:00053918.8NOTCH1, PMP22

Publications for Nerve Compression Syndrome

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Articles related to Nerve Compression Syndrome:

(show all 19)
idTitleAuthorsYear
1
Anterior interosseous nerve compression syndrome: is there a role for endoscopy? (21786008)
2011
2
Hypertrophic abductor hallucis muscle with nerve compression syndrome. (21381535)
2010
3
Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen. (24557672)
2007
4
Unusual complication of an opposition tendon transfer at the wrist: ulnar nerve compression syndrome. (15249086)
2004
5
Management of nerve compression syndrome in musicians. (12852670)
2003
6
Bilateral radial nerve compression syndrome in an elite swimmer: a case report. (12130418)
2002
7
Acute ulnar nerve compression syndrome in a powerlifter with triceps tendon rupture--a case report. (10853704)
2000
8
Ulnar nerve compression syndrome due to an anomalous arch of the ulnar nerve piercing the flexor carpi ulnaris: a case report. (8683063)
1996
9
Cochleovestibular nerve compression syndrome. II. Vestibular nerve histopathology and theory of pathophysiology. (1518348)
1992
10
Cochleovestibular nerve compression syndrome. I. Clinical features and audiovestibular findings. (1518347)
1992
11
Dorsal interrosseous nerve compression syndrome from the use of a Canadian crutch. (3237242)
1988
12
Bilateral anomalous course of the ulnar nerve at the wrist causing ulnar and median nerve compression syndrome. Case report. (3668645)
1987
13
Suprascapular nerve compression syndrome. (6463842)
1984
14
Anterior interosseous nerve compression syndrome: from metastatic bronchogenic carcinoma to the forearm. (6622577)
1983
15
Suprascapular nerve compression syndrome. (7432615)
1980
16
Medial epicondylectomy for ulnar nerve compression syndrome at the elbow. (455838)
1979
17
Femoral nerve compression syndrome with paresis of the quadriceps muscle caused by radiotherapy of malignant tumours. A report of four cases. (1199719)
1975
18
Radial palsy following muscular effort. A nerve compression syndrome possibly related to a fibrous arch of the lateral head of the triceps. (4327331)
1971
19
Nerve compression syndrome in derangements of the proximal and distal radial ulnar joints. (4300971)
1968

Variations for Nerve Compression Syndrome

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Clinvar genetic disease variations for Nerve Compression Syndrome:

6
id Gene Variation Type Significance SNP ID Assembly Location
1PMP22NM_000304.3(PMP22): c.353C> T (p.Thr118Met)single nucleotide variantPathogenicrs104894619GRCh37Chr 17, 15134364: 15134364
2PMP22NM_000304.3(PMP22): c.19_20delAG (p.Ser7Tyrfs)deletionPathogenicGRCh37Chr 17, 15164025: 15164026
3PMP22NM_000304.3(PMP22): c.199G> A (p.Ala67Thr)single nucleotide variantPathogenicrs104894623GRCh37Chr 17, 15142908: 15142908
4PMP22NM_000304.3(PMP22): c.65C> T (p.Ser22Phe)single nucleotide variantPathogenicrs104894625GRCh37Chr 17, 15163980: 15163980

Expression for genes affiliated with Nerve Compression Syndrome

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Search GEO for disease gene expression data for Nerve Compression Syndrome.

Pathways for genes affiliated with Nerve Compression Syndrome

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Pathways related to Nerve Compression Syndrome according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1NOTCH1, PMP22

Compounds for genes affiliated with Nerve Compression Syndrome

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Sources:
43Novoseek, 24HMDB
See all sources

Compounds related to Nerve Compression Syndrome according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1serine439.1NOTCH1, PMP22
2aspartate439.0NOTCH1, PMP22
3retinoic acid43 249.8NOTCH1, PMP22

GO Terms for genes affiliated with Nerve Compression Syndrome

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Biological processes related to Nerve Compression Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of cell proliferationGO:00082859.1NOTCH1, PMP22

Products for genes affiliated with Nerve Compression Syndrome

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  • Antibodies
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Sources for Nerve Compression Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet