MCID: NRV004
MIFTS: 37

Nerve Compression Syndrome

Categories: Neuronal diseases

Aliases & Classifications for Nerve Compression Syndrome

MalaCards integrated aliases for Nerve Compression Syndrome:

Name: Nerve Compression Syndrome 12 14 69
Entrapment Neuropathies 51 69
Hereditary Liability to Pressure Palsies 69
Peripheral Nerve Entrapment Syndrome 12
Nerve Compression Syndromes 41
Compression Neuropathy 12
Entrapment Neuropathy 12

Classifications:



External Ids:

Disease Ontology 12 DOID:573
MeSH 41 D009408
NCIt 46 C27221
SNOMED-CT 64 155085004 45781009

Summaries for Nerve Compression Syndrome

MalaCards based summary : Nerve Compression Syndrome, also known as entrapment neuropathies, is related to neuropathy, hereditary, with liability to pressure palsies and ulnar neuropathy, and has symptoms including abnormal motor neuron morphology, motor conduction block and neuralgia. An important gene associated with Nerve Compression Syndrome is PMP22 (Peripheral Myelin Protein 22). The drugs Prednisolone and Lidocaine have been mentioned in the context of this disorder. Affiliated tissues include skin, testes and liver.

Wikipedia : 72 Nerve compression syndrome or compression neuropathy, also known as entrapment neuropathy, is a medical... more...

Related Diseases for Nerve Compression Syndrome

Graphical network of the top 20 diseases related to Nerve Compression Syndrome:



Diseases related to Nerve Compression Syndrome

Symptoms & Phenotypes for Nerve Compression Syndrome

Human phenotypes related to Nerve Compression Syndrome:

31
# Description HPO Frequency HPO Source Accession
1 abnormal motor neuron morphology 31 HP:0002450
2 motor conduction block 31 HP:0012078

UMLS symptoms related to Nerve Compression Syndrome:


neuralgia

Drugs & Therapeutics for Nerve Compression Syndrome

Drugs for Nerve Compression Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 201)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
2
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 137-58-6 3676
3
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
4
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
5
Gabapentin Approved, Investigational Phase 4,Phase 3 60142-96-3 3446
6
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
7
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
8
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
9
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 124-94-7 31307
10
Ropivacaine Approved Phase 4 84057-95-4 175805 71273
11
gamma-Aminobutyric acid Approved, Investigational Phase 4,Phase 3 56-12-2 119
12
Ibuprofen Approved Phase 4,Phase 2 15687-27-1 3672
13
Hydrocodone Approved, Illicit Phase 4 125-29-1 5284569
14
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
15
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
16
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 2 76-42-6 5284603
17
Vitamin A Approved, Nutraceutical, Vet_approved Phase 4 68-26-8, 11103-57-4 445354
18
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 2,Phase 3 59-30-3 6037
19 tannic acid Approved, Nutraceutical Phase 4
20 Prednisolone acetate Phase 4,Phase 2,Phase 3
21 Analgesics Phase 4,Phase 3,Phase 2
22 glucocorticoids Phase 4,Phase 3,Phase 2
23 Respiratory System Agents Phase 4,Phase 3
24 Methylprednisolone acetate Phase 4,Phase 2,Phase 3
25 Methylprednisolone Hemisuccinate Phase 4,Phase 2,Phase 3
26 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
27 Sodium Channel Blockers Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
28 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
29 Neuroprotective Agents Phase 4,Phase 2,Phase 3
30 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
31 Tranquilizing Agents Phase 4,Phase 3,Phase 2
32 Analgesics, Non-Narcotic Phase 4,Phase 2
33 Anesthetics Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
34 Hormone Antagonists Phase 4,Phase 3,Phase 2
35 Anesthetics, Local Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
36 Hormones Phase 4,Phase 3,Phase 2
37 Diuretics, Potassium Sparing Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
38 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
39 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
40 Anti-Arrhythmia Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
41 Anti-Asthmatic Agents Phase 4,Phase 3
42 Anticonvulsants Phase 4,Phase 3
43 Antiemetics Phase 4,Phase 2,Phase 3
44 Antimanic Agents Phase 4,Phase 3
45 Prednisolone hemisuccinate Phase 4,Phase 2,Phase 3
46 Prednisolone phosphate Phase 4,Phase 2,Phase 3
47 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
48 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 2
49 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1
50 Psychotropic Drugs Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 252)

# Name Status NCT ID Phase Drugs
1 Postoperative Alpha Lipoic Acid in the Carpal Tunnel Syndrome: a Randomized Controlled Trial. Completed NCT01895621 Phase 4
2 Local Steroid Injection vs Placebo in Carpal Tunnel Syndrome Completed NCT02652390 Phase 4 Methylprednisolone 80 mg;Methylprednisolone 40 mg
3 Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol for Carpal Tunnel and Distal Radius Fracture Surgeries Completed NCT02313675 Phase 4 Acetaminophen;Ketorolac Tromethamine;Saline
4 Efficacy Study of Local Steroid Injection and Wrist Splinting for Carpal Tunnel Syndrome Completed NCT02140632 Phase 4
5 Bupivacaine Versus Lidocaine Local Anesthesia Completed NCT01751347 Phase 4 Bupivacaine;Lidocaine
6 Length of Post Operative Dressing After Carpal Tunnel Release Completed NCT01310218 Phase 4
7 A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions Completed NCT00904202 Phase 4 Placebo Capsules + Placebo Patch;Placebo capsules + Lidoderm®;Gabapentin + Placebo;Gabapentin + Lidoderm®;Gabapentin 300 mg capsules 1800 mg/day + placebo patch;Gabapentin 1800 mg/day + Lidoderm patch
8 Patient Controlled Regional Analgesia Following Carpal Tunnel Release: A Double-Blind Study Using Distal Perineural Catheters Completed NCT00678314 Phase 4 Ropivacaine 0.2%;Ropivacaine 0.75%;Normal saline
9 Therapeutic Effects Analysis of Pudendal Nerve Infiltrations After 3 Months, in Patients Suffering of Pudendal Neuralgia Completed NCT00851513 Phase 4 Lidocaine;Depmedrol
10 Short and Long Term Exposure to Unique, Time-Varying Pulsed Electro-Magnetic Fields in Refractory Carpal Tunnel Syndrome Completed NCT00277563 Phase 4
11 Narcotic vs. Non-narcotic Pain Study Protocol Recruiting NCT01974609 Phase 4 Narcotic;non-narcotic
12 Non-surgical Treatment of Carpal Tunnel Syndrome: Night Splint Versus Local Corticosteroid Infiltration Active, not recruiting NCT03196817 Phase 4 betamethasone dipropionate, betamethasone disodium phosphate and lidocaine 2%
13 Injection Versus Splinting in Carpal Tunnel Syndrome Active, not recruiting NCT02038452 Phase 4 Depo-Medrone
14 Post-operative Analgesia in Elective, Soft-tissue Hand Surgery Enrolling by invitation NCT02029235 Phase 4 Acetaminophen/Hydrocodone;Acetaminophen/Ibuprofen
15 Preoperative Antibiotics for Carpal Tunnel Release Surgery Not yet recruiting NCT03432858 Phase 4 Vancomycin;Cefazolin;Saline Solution
16 Patient Satisfaction With Pain Relief After Ambulatory Hand Surgery Terminated NCT01588158 Phase 4 Acetaminophen;Vicodin
17 Lidocaine and Triamcinolone vs Saline Trigger Point Injection for Treatment of Chronic Abdominal Wall Pain Withdrawn NCT02748395 Phase 4 Triamcinolone;Lidocaine
18 Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot−Marie−Tooth Neuropathy Type 1A (CMT1A) Unknown status NCT01289704 Phase 2, Phase 3
19 Carpal Tunnel Syndrome Release Using PSU Retractor Unknown status NCT01017471 Phase 3
20 High Dose Ascorbic Acid Treatment of CMT1A Completed NCT00484510 Phase 2, Phase 3 Ascorbic acid (Vitamin C);placebo
21 Acetyl-l-carnitine to Enhance Nerve Regeneration in Carpal Tunnel Syndrome Completed NCT02141035 Phase 2, Phase 3 Acetyl-l-carnitine;placebo
22 Sonographic Examination Cubital Tunnel Release Completed NCT02739945 Phase 3
23 Sonography-guided Steroid Injection for Carpal Tunnel Syndrome Completed NCT02575729 Phase 3 betamethasone
24 Preoperative Gabapentine for Carpal Tunnel Completed NCT01632215 Phase 3 Gabapentine
25 Steroid Injection Treatment of Carpal Tunnel Syndrome Completed NCT00806871 Phase 2, Phase 3 Methylprednisolone 40 mg;Methylprednisolone 80 mg;Sodium chloride
26 Gabapentin for Carpal Tunnel Syndrome Completed NCT00137735 Phase 3 Gabapentin
27 Effects of Botulinum Toxin Injections in Patients With Hereditary Spastic Paraplegia Completed NCT02604186 Phase 2, Phase 3
28 Compassionate Treatment of Patients With Inborn Errors of Bile Acid Metabolism With Cholic Acid Completed NCT00007020 Phase 3 Cholic Acids
29 Assessing Long Term Safety and Tolerability of PXT3003 in Patients With Charcot-Marie-Tooth Disease Type 1A Recruiting NCT03023540 Phase 3 PXT3003
30 Setmelanotide Phase 2 Treatment Trial in Patients With Rare Genetic Disorders of Obesity Recruiting NCT03013543 Phase 2, Phase 3 Setmelanotide
31 Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients (PLEO-CMT) Active, not recruiting NCT02579759 Phase 3 PXT3003 dose 1;PXT3003 dose 2;placebo
32 Assessment of the Effectiveness of Ultrasound-guided Acupuncture in the Management of Carpal Tunnel Syndrome Not yet recruiting NCT02870673 Phase 2, Phase 3 SHINCORT;XYLOCAINE
33 Open-Label Rollover Study of PBI 4050 in Subjects With Alström Syndrome Not yet recruiting NCT03184584 Phase 2, Phase 3 PBI-4050
34 Erythropoietin Spinal Cord Compression Randomized Trial Terminated NCT00220675 Phase 2, Phase 3 Erythropoietin infusion
35 NeuroPath Comparative Validation Study Plan Terminated NCT00393549 Phase 3
36 A Study of AQUAVAN® Injection in the Presence of Pre-Medication in Patients Undergoing Minor Surgical Procedures Terminated NCT00209560 Phase 3 fospropofol disodium
37 Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome Terminated NCT00266214 Phase 3 lidocaine patch 5%
38 Minocycline to Reduce Pain After Carpal Tunnel Release Unknown status NCT02051296 Phase 2 Minocycline;placebo
39 Carpal Tunnel Syndrome and Static Magnetic Field Therapy Unknown status NCT00521495 Phase 2
40 Carpal Tunnel Syndrome Treated With 830nm Diode Laser Unknown status NCT00514462 Phase 1, Phase 2
41 Safety and Tolerability of PBI-4050 and Its Effects on the Biomarkers in Subjects With Alström Syndrome Unknown status NCT02739217 Phase 2 PBI-4050
42 Therapeutic Metabolic Intervention in Patients With Spastic Paraplegia SPG5 Unknown status NCT02314208 Phase 2 Xenbilox;Tahor
43 Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease Completed NCT00541164 Phase 1, Phase 2 Coenzyme Q10
44 Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease Completed NCT02561702 Phase 2 Mexiletine
45 Phase II, Randomized, Placebo-controlled Trial in Patients With Charcot-marie-tooth Disease Type 1A Completed NCT01401257 Phase 2 PXT3003 Low dose;PXT3003 Intermediate Dose;PXT3003 High Dose
46 Ascorbic Acid Treatment in CMT1A Trial (AATIC) Completed NCT00271635 Phase 2 Placebo;ascorbic acid
47 The Treatment of the Median Nerve for the Elimination of the Symptoms Associated With the Carpal Tunnel Syndrome Completed NCT00634738 Phase 1, Phase 2
48 L-Serine Supplementation in Hereditary Sensory Neuropathy Type 1 Completed NCT01733407 Phase 1, Phase 2 L-serine;placebo
49 Comparison of Effect of Anterior Subcutaneous and Submuscular Transposition on Cubital Tunnel Syndrome Completed NCT01109901 Phase 2
50 Treatment of Thoracic Outlet Syndrome (TOS) With Botox Completed NCT00444886 Phase 2 Botulinum Toxin Type A injection (BOTOX);Botulinum Toxin Type A injection (BOTOX)

Search NIH Clinical Center for Nerve Compression Syndrome

Cochrane evidence based reviews: nerve compression syndromes

Genetic Tests for Nerve Compression Syndrome

Anatomical Context for Nerve Compression Syndrome

MalaCards organs/tissues related to Nerve Compression Syndrome:

38
Skin, Testes, Liver, Heart, Spinal Cord, Brain

Publications for Nerve Compression Syndrome

Articles related to Nerve Compression Syndrome:

(show all 23)
# Title Authors Year
1
Redo Microvascular Decompression in a Patient of Resistant Cochleovestibular Nerve Compression Syndrome. ( 29114297 )
2017
2
Peripheral Neuropathy and Nerve Compression Syndromes in Burns. ( 28888304 )
2017
3
Cochleovestibular nerve compression syndrome due to intrameatal Anterior Inferior Cerebellar Artery loop: synthesis of best evidence for clinical decisions. ( 27647022 )
2016
4
Resolution of intractable retching following mobilization of a dolichoectatic vertebral artery: case report of a unique brainstem-cranial nerve compression syndrome. ( 27767394 )
2016
5
Anterior interosseous nerve compression syndrome: is there a role for endoscopy? ( 21786008 )
2011
6
Hypertrophic abductor hallucis muscle with nerve compression syndrome. ( 21381535 )
2010
7
Differential diagnosis of cervical nerve compression syndrome of the external intervertebral foramen. ( 24557672 )
2007
8
Unusual complication of an opposition tendon transfer at the wrist: ulnar nerve compression syndrome. ( 15249086 )
2004
9
Management of nerve compression syndrome in musicians. ( 12852670 )
2003
10
Bilateral radial nerve compression syndrome in an elite swimmer: a case report. ( 12130418 )
2002
11
Acute ulnar nerve compression syndrome in a powerlifter with triceps tendon rupture--a case report. ( 10853704 )
2000
12
Ulnar nerve compression syndrome due to an anomalous arch of the ulnar nerve piercing the flexor carpi ulnaris: a case report. ( 8683063 )
1996
13
Cochleovestibular nerve compression syndrome. II. Vestibular nerve histopathology and theory of pathophysiology. ( 1518348 )
1992
14
Cochleovestibular nerve compression syndrome. I. Clinical features and audiovestibular findings. ( 1518347 )
1992
15
Dorsal interrosseous nerve compression syndrome from the use of a Canadian crutch. ( 3237242 )
1988
16
Bilateral anomalous course of the ulnar nerve at the wrist causing ulnar and median nerve compression syndrome. Case report. ( 3668645 )
1987
17
Suprascapular nerve compression syndrome. ( 6463842 )
1984
18
Anterior interosseous nerve compression syndrome: from metastatic bronchogenic carcinoma to the forearm. ( 6622577 )
1983
19
Suprascapular nerve compression syndrome. ( 7432615 )
1980
20
Medial epicondylectomy for ulnar nerve compression syndrome at the elbow. ( 455838 )
1979
21
Femoral nerve compression syndrome with paresis of the quadriceps muscle caused by radiotherapy of malignant tumours. A report of four cases. ( 1199719 )
1975
22
Radial palsy following muscular effort. A nerve compression syndrome possibly related to a fibrous arch of the lateral head of the triceps. ( 4327331 )
1971
23
Nerve compression syndrome in derangements of the proximal and distal radial ulnar joints. ( 4300971 )
1968

Variations for Nerve Compression Syndrome

Expression for Nerve Compression Syndrome

Search GEO for disease gene expression data for Nerve Compression Syndrome.

Pathways for Nerve Compression Syndrome

GO Terms for Nerve Compression Syndrome

Sources for Nerve Compression Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....