MCID: NRV006
MIFTS: 39

Nervous System Cancer malady

Cancer diseases, Neuronal diseases categories
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Summaries for Nervous System Cancer

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Disease Ontology:8 An organ system cancer located in the nervous sytem that affects the central or peripheral nervous system.

MalaCards based summary: Nervous System Cancer, also known as malignant neoplasm of nervous system, is related to central nervous system hematologic cancer and malignant glioma. An important gene associated with Nervous System Cancer is ARSA (arylsulfatase A). The compounds ganglioside and glutamine have been mentioned in the context of this disorder. Affiliated tissues include the nervous sytem and brain, and related mouse phenotypes are taste/olfaction and hearing/vestibular/ear.

Wikipedia:65 A nervous system neoplasm is a tumor affecting the nervous system. Types include: more...

Aliases & Classifications for Nervous System Cancer

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Sources:
8Disease Ontology, 62UMLS, 44Novoseek, 34MeSH, 57SNOMED-CT
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Nervous System Cancer, Aliases & Descriptions:

Name: Nervous System Cancer 8
Malignant Neoplasm of Nervous System 8 62
Tumor of the Nervous System 8 62
Neoplasm of Nervous System 8 62
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm 62
 
Nervous System Neoplasms 62
Nervous System Neoplasm 8
Nervous System Tumor 44
Neural Neoplasm 8
Neural Tumor 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:3093
SNOMED-CT57 188306000
MeSH34 D009380

Related Diseases for Nervous System Cancer

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Diseases in the Central Nervous System Cancer family:

nervous system cancer

Diseases related to Nervous System Cancer via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 55)
idRelated DiseaseScoreTop Affiliating Genes
1central nervous system hematologic cancer30.0ENO2, ARSA
2malignant glioma30.0CASP3, ENO2
3medulloblastoma30.0ENO2, CASP3
4brain cancer29.9ENO2, CASP3
5central nervous system cancer10.6
6endotheliitis10.4
7autonomic nervous system neoplasm10.3
8krabbe disease10.3ARSA
9leukemia10.3
10neuronitis10.2
11childhood leukemia10.2
12central neurocytoma10.1
13ectomesenchymoma10.1
14olfactory neural tumor10.1
15neuroblastoma10.1
16neuroma10.1
17glioma somatic10.0
18neuroepithelioma10.0ENO2, CASP3
19ganglioglioma10.0
20hyperprolactinemia10.0
21neurofibromatosis10.0
22pleomorphic xanthoastrocytoma10.0
23melanoma10.0
24meningitis10.0
25oligodendroglioma10.0
26perineurioma10.0
27mowat-wilson syndrome10.0
28pilocytic astrocytoma10.0
29turcot syndrome10.0
30prion disease10.0ENO2, CASP3
31lung benign neoplasm10.0CASP3, ENO2
32astrocytoma10.0
33brucellosis10.0
34meningioma10.0
35peripheral nervous system neoplasm10.0
36spinal cancer10.0
37dermatofibrosarcoma protuberans10.0
38vascular disease10.0ENO2, CASP3
39pheochromocytoma10.0CASP3, ENO2
40brain injury10.0
41obesity10.0
42wilms tumor10.0
43ganglioneuroma10.0
44paraganglioma10.0
45fibrosarcoma10.0
46ganglioneuroblastoma10.0
47leiomyosarcoma10.0
48rhabdomyosarcoma10.0
49rapid-onset childhood obesity - hypothalamic dysfunction - hypoventilation - autonomic dysregulation syndrome10.0
50lung small cell carcinoma9.9ENO2, CASP3

Graphical network of the top 20 diseases related to Nervous System Cancer:



Diseases related to nervous system cancer

Symptoms for Nervous System Cancer

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Drugs & Therapeutics for Nervous System Cancer

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Drug clinical trials:

Search ClinicalTrials for Nervous System Cancer

Search NIH Clinical Center for Nervous System Cancer

Genetic Tests for Nervous System Cancer

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Anatomical Context for Nervous System Cancer

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MalaCards organs/tissues related to Nervous System Cancer:

32
Brain

FMA organs/tissues related to Nervous System Cancer:

14
The nervous sytem

Animal Models for Nervous System Cancer or affiliated genes

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MGI Mouse Phenotypes related to Nervous System Cancer:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.1CASP3, ENO2
2MP:00053779.0CASP3, ARSA
3MP:00053868.4ARSA, ENO2, CASP3
4MP:00036318.2CASP3, ENO2, ARSA

Publications for Nervous System Cancer

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Articles related to Nervous System Cancer:

(show all 18)
idTitleAuthorsYear
1
Identification of miRNAs as potential new biomarkers for nervous system cancer. (25139093)
2014
2
Vocational identity, positive affect, and career thoughts in a group of young adult central nervous system cancer survivors. (25035908)
2014
3
Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients. (23661397)
2013
4
Medulloblastoma and Brucellosis - Molecular Evidence of Brucella sp in Association with Central Nervous System Cancer. (21475718)
2011
5
Comparison of time trends in brain and central nervous system cancer mortality (1990-2006) between countries based on the WHO mortality database. (21273379)
2011
6
Long-term health experience of jet engine manufacturing workers: IV. A comparison of central nervous system cancer ascertainment using mortality and incidence data. (20816315)
2010
7
Pain in children with central nervous system cancer: a review of the literature. (20591796)
2010
8
School-aged children after the end of successful treatment of non-central nervous system cancer: longitudinal assessment of health-related quality of life, anxiety and coping. (19594611)
2009
9
Induction of cytotoxicity, apoptosis and cell cycle arrest by 1-t-butyl carbamoyl, 7-methyl-indole-3-ethyl isothiocyanate (NB7M) in nervous system cancer cells. (19920894)
2009
10
Comparison of time trends in brain central nervous system cancer incidence (1973-97) in East Asia, Europe and USA, from Cancer Incidence in Five Continents Vols IV-VIII. (18772173)
2008
11
Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy. (18338171)
2008
12
Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. (18415683)
2008
13
Cytotoxicity and oncostatic activity of the thiazolidinedione derivative CGP 52608 on central nervous system cancer cells. (15194216)
2004
14
Nervous system cancer mortality in an industrialized area of Brazil 1980-1993. (10920400)
2000
15
Exploitation of immune mechanisms in the treatment of central nervous system cancer. (10914414)
2000
16
Risk of nervous system cancer among workers exposed to lead. (8673517)
1996
17
Human malignant astrocytoma xenografts migrate in rat brain: a model for central nervous system cancer research. (2651679)
1989
18
Brain and central nervous system cancer mortality in U. S. rubber workers. (6953785)
1982

Variations for Nervous System Cancer

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Expression for genes affiliated with Nervous System Cancer

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Expression patterns in normal tissues for genes affiliated with Nervous System Cancer

Search GEO for disease gene expression data for Nervous System Cancer.

Pathways for genes affiliated with Nervous System Cancer

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Compounds for genes affiliated with Nervous System Cancer

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Compounds related to Nervous System Cancer according to GeneCards/GeneDecks:

(show all 13)
idCompoundScoreTop Affiliating Genes
1ganglioside449.6ARSA, ENO2
2glutamine449.5ENO2, ARSA
3docetaxel44 50 61 1112.4ENO2, CASP3
4creatinine449.3ENO2, ARSA
5etoposide44 50 61 1112.3ENO2, CASP3
6magnesium44 24 1111.3ARSA, ENO2
7pd 98,059449.3ENO2, CASP3
8ceramide449.3CASP3, ARSA
9superoxide44 2410.2ENO2, CASP3
10leucine449.2ARSA, ENO2
11cisplatin44 50 61 1112.2ENO2, CASP3
12aspartate449.0ARSA, ENO2
13lactate448.8ARSA, ENO2, CASP3

GO Terms for genes affiliated with Nervous System Cancer

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Products for genes affiliated with Nervous System Cancer

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  • Antibodies
  • Proteins
  • Lysates

Sources for Nervous System Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet