MCID: NRV006
MIFTS: 32

Nervous System Cancer malady

Neuronal diseases, Cancer diseases categories

Summaries for Nervous System Cancer

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Disease Ontology:9 An organ system cancer located in the nervous sytem that affects the central or peripheral nervous system.

MalaCards based summary: Nervous System Cancer, also known as neuroepithelial, perineurial, and schwann cell neoplasm, is related to central nervous system cancer and medulloblastoma. An important gene associated with Nervous System Cancer is ARSA (arylsulfatase A). The compounds ganglioside and glutamine have been mentioned in the context of this disorder. Affiliated tissues include the nervous sytem and brain, and related mouse phenotypes are taste/olfaction and hearing/vestibular/ear.

Aliases & Classifications for Nervous System Cancer

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Sources:
9Disease Ontology, 43Novoseek, 60UMLS, 55SNOMED-CT, 33MeSH
See all sources

Nervous System Cancer, Aliases & Descriptions:

Name: Nervous System Cancer 9
Neuroepithelial, Perineurial, and Schwann Cell Neoplasm 60
Primary Malignant Neoplasm of Nervous System 60
Malignant Neoplasm of Nervous System 9
Malignant Neurologic Neoplasms 60
Tumor of the Nervous System 9
 
Neoplasm of Nervous System 9
Nervous System Neoplasms 60
Nervous System Neoplasm 9
Nervous System Tumor 43
Neural Neoplasm 9
Neural Tumor 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:3093
SNOMED-CT55 188306000
MeSH33 D009380

Related Diseases for Nervous System Cancer

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Diseases in the Nervous System Cancer family:

Central Nervous System Cancer

Diseases related to Nervous System Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idRelated DiseaseScoreTop Affiliating Genes
1central nervous system cancer31.0ARSA, ENO2
2medulloblastoma30.0ENO2, CASP3
3malignant glioma30.0CASP3, ENO2
4brain cancer29.9ENO2, CASP3
5autonomic nervous system neoplasm10.4
6endotheliitis10.4
7krabbe disease10.3ARSA
8leukemia10.3
9olfactory neural tumor10.2
10insulin-like growth factor i10.2
11neuronitis10.2
12childhood leukemia10.2
13ectomesenchymoma10.1
14central neurocytoma10.1
15malignant ectomesenchymoma10.1
16neuroblastoma10.1
17neuroma10.1
18glioma susceptibility 110.0
19li-fraumeni syndrome10.0
20choroid plexus papilloma10.0
21central nervous system hematologic cancer10.0
22infantile myofibromatosis10.0
23meningioma, familial10.0
24astrocytoma10.0
25brucellosis10.0
26peripheral nervous system neoplasm10.0
27spinal cancer10.0
28mismatch repair cancer syndrome10.0
29mowat-wilson syndrome10.0
30hyperprolactinemia10.0
31schwannomatosis10.0
32ganglioglioma10.0
33neurofibromatosis10.0
34tuberous sclerosis10.0
35pleomorphic xanthoastrocytoma10.0
36facial paralysis10.0
37melanoma10.0
38meningitis10.0
39oligodendroglioma10.0
40perineurioma10.0
41pilocytic astrocytoma10.0
42ewing sarcoma10.0ENO2, CASP3
43brain disease10.0CASP3, ENO2
44dermatofibrosarcoma protuberans10.0
45malignant mediastinal neurogenic neoplasm10.0
46lung benign neoplasm10.0CASP3, ENO2
47vascular disease10.0ENO2, CASP3
48pheochromocytoma10.0ENO2, CASP3
49obesity10.0
50wilms tumor10.0

Graphical network of the top 20 diseases related to Nervous System Cancer:



Diseases related to nervous system cancer

Symptoms for Nervous System Cancer

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Drugs & Therapeutics for Nervous System Cancer

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Drug clinical trials:

Search ClinicalTrials for Nervous System Cancer

Search NIH Clinical Center for Nervous System Cancer

Genetic Tests for Nervous System Cancer

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Anatomical Context for Nervous System Cancer

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MalaCards organs/tissues related to Nervous System Cancer:

31
Brain

FMA organs/tissues related to Nervous System Cancer:

14
The nervous sytem

Animal Models for Nervous System Cancer or affiliated genes

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MGI Mouse Phenotypes related to Nervous System Cancer:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053949.1ENO2, CASP3
2MP:00053779.0ARSA, CASP3
3MP:00053868.4ARSA, ENO2, CASP3
4MP:00036318.2CASP3, ENO2, ARSA

Publications for Nervous System Cancer

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Articles related to Nervous System Cancer:

(show all 20)
idTitleAuthorsYear
1
Clinical characteristics, pathophysiology, and management of noncentral nervous system cancer-related cognitive impairment in adults. (25483452)
2015
2
Five-year relative survival rate of brain and other nervous system cancer in the USA, Europe and Japan. (25717112)
2015
3
Brain and central nervous system cancer incidence in navarre (Spain), 1973-2008 and projections for 2014. (25561983)
2015
4
Identification of miRNAs as potential new biomarkers for nervous system cancer. (25139093)
2014
5
Vocational identity, positive affect, and career thoughts in a group of young adult central nervous system cancer survivors. (25035908)
2014
6
Detection of MGMT, RASSF1A, p15INK4B, and p14ARF promoter methylation in circulating tumor-derived DNA of central nervous system cancer patients. (23661397)
2013
7
Medulloblastoma and Brucellosis - Molecular Evidence of Brucella sp in Association with Central Nervous System Cancer. (21475718)
2011
8
Comparison of time trends in brain and central nervous system cancer mortality (1990-2006) between countries based on the WHO mortality database. (21273379)
2011
9
Long-term health experience of jet engine manufacturing workers: IV. A comparison of central nervous system cancer ascertainment using mortality and incidence data. (20816315)
2010
10
Pain in children with central nervous system cancer: a review of the literature. (20591796)
2010
11
School-aged children after the end of successful treatment of non-central nervous system cancer: longitudinal assessment of health-related quality of life, anxiety and coping. (19594611)
2009
12
Comparison of time trends in brain central nervous system cancer incidence (1973-97) in East Asia, Europe and USA, from Cancer Incidence in Five Continents Vols IV-VIII. (18772173)
2008
13
Molecular predictors of human nervous system cancer responsiveness to enediyne chemotherapy. (18338171)
2008
14
Neuropsychological sequelae of non-central nervous system cancer and cancer therapy. (18415683)
2008
15
Cytotoxicity and oncostatic activity of the thiazolidinedione derivative CGP 52608 on central nervous system cancer cells. (15194216)
2004
16
Nervous system cancer mortality in an industrialized area of Brazil 1980-1993. (10920400)
2000
17
Exploitation of immune mechanisms in the treatment of central nervous system cancer. (10914414)
2000
18
Risk of nervous system cancer among workers exposed to lead. (8673517)
1996
19
Human malignant astrocytoma xenografts migrate in rat brain: a model for central nervous system cancer research. (2651679)
1989
20
Brain and central nervous system cancer mortality in U. S. rubber workers. (6953785)
1982

Variations for Nervous System Cancer

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Expression for genes affiliated with Nervous System Cancer

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Search GEO for disease gene expression data for Nervous System Cancer.

Pathways for genes affiliated with Nervous System Cancer

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Compounds for genes affiliated with Nervous System Cancer

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Compounds related to Nervous System Cancer according to GeneCards Suite gene sharing:

(show all 13)
idCompoundScoreTop Affiliating Genes
1ganglioside439.6ARSA, ENO2
2glutamine439.5ENO2, ARSA
3docetaxel43 49 59 1212.4ENO2, CASP3
4creatinine439.3ENO2, ARSA
5etoposide43 49 59 1212.3ENO2, CASP3
6magnesium43 24 1211.3ARSA, ENO2
7pd 98,059439.3ENO2, CASP3
8ceramide439.3CASP3, ARSA
9superoxide43 2410.2ENO2, CASP3
10leucine439.2ARSA, ENO2
11cisplatin43 49 59 1212.2ENO2, CASP3
12aspartate439.0ARSA, ENO2
13lactate438.8ARSA, ENO2, CASP3

GO Terms for genes affiliated with Nervous System Cancer

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Products for genes affiliated with Nervous System Cancer

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  • Antibodies
  • Proteins
  • Lysates
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  • Proteins
  • Kits and Assays

Sources for Nervous System Cancer

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet