MCID: NRL008
MIFTS: 22

Neural Crest Tumor malady

Cancer diseases category

Summaries for Neural Crest Tumor

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32MalaCards
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MalaCards: Neural Crest Tumor, also known as neural crest-derived tumors, is related to neuroblastoma and beckwith-wiedemann syndrome. An important gene associated with Neural Crest Tumor is SDHAF2 (succinate dehydrogenase complex assembly factor 2), and among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. and Carbon metabolism. The compounds thenoyltrifluoroacetone and nad+ have been mentioned in the context of this disorder.

Aliases & Classifications for Neural Crest Tumor

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42NIH Rare Diseases, 60UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases


Aliases & Descriptions:

neural crest tumor 42 60
neural crest-derived tumors 42


Related Diseases for Neural Crest Tumor

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Neural Crest Tumor:



Diseases related to neural crest tumor

Clinical Features for Neural Crest Tumor

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Drugs & Therapeutics for Neural Crest Tumor

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Neural Crest Tumor

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Genetic Tests for Neural Crest Tumor

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Anatomical Context for Neural Crest Tumor

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Animal Models for Neural Crest Tumor or affiliated genes

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Publications for Neural Crest Tumor

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Genetic Variations for Neural Crest Tumor

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Expression for genes affiliated with Neural Crest Tumor

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neural Crest Tumor

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Pathways for genes affiliated with Neural Crest Tumor

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Sources:
53Reactome, 29KEGG, 37NCBI BioSystems Database, 12EMD Millipore
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Compounds for genes affiliated with Neural Crest Tumor

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Sources:
44Novoseek, 11DrugBank, 28IUPHAR, 24HMDB
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Compounds related to Neural Crest Tumor according to GeneCards/GeneDecks:

(show all 13)
idCompoundScoreTop Affiliating Genes
1thenoyltrifluoroacetone44 1110.2SDHA, SDHB
2nad+449.1SDHA, SDHB
3mibg449.0SDHB, SDHD
4catecholamine448.7NPY, SDHD, SDHB
5fumarate44 119.7SDHC, SDHB, SDHD
6UBIQUINONE-1118.3SDHA, SDHC, SDHB, SDHD
72-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol118.2SDHD, SDHB, SDHC, SDHA
8succinic acid28 11 2410.2SDHD, SDHB, SDHC, SDHA
9iron-sulfur448.2SDHD, SDHB, SDHC, SDHA
10ubiquinone448.2SDHD, SDHB, SDHC, SDHA
11succinate448.2SDHD, SDHB, SDHC, SDHA
12iron44 249.1SDHD, SDHB, SDHC, SDHA
13oxygen44 248.7SDHA, SDHC, SDHB, SDHD

GO Terms for genes affiliated with Neural Crest Tumor

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16Gene Ontology
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Cellular components related to Neural Crest Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1mitochondrial respiratory chain complex IIGO:0057497.9SDHA, SDHC, SDHB, SDHD
2mitochondrial inner membraneGO:0057437.7SDHD, SDHB, SDHC, SDHA
3mitochondrionGO:0057397.6SDHA, SDHC, SDHB, SDHAF2, SDHD

Biological processes related to Neural Crest Tumor according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1oxidation-reduction processGO:0551149.3SDHA, SDHC
2succinate metabolic processGO:0061059.1SDHA, SDHB
3aerobic respirationGO:0090608.9SDHC, SDHB
4tricarboxylic acid cycleGO:0060998.1SDHA, SDHC, SDHB, SDHD
5respiratory electron transport chainGO:0229048.1SDHD, SDHB, SDHC, SDHA
6cellular metabolic processGO:0442378.1SDHD, SDHB, SDHC, SDHA
7small molecule metabolic processGO:0442817.7SDHD, SDHB, SDHC, SDHA

Molecular functions related to Neural Crest Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heme bindingGO:0200379.3SDHC, SDHD
2succinate dehydrogenase (ubiquinone) activityGO:0081779.1SDHA, SDHB
3ubiquinone bindingGO:0480399.0SDHB, SDHD
4electron carrier activityGO:0090558.2SDHC, SDHB, SDHD

Products for genes affiliated with Neural Crest Tumor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neural Crest Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet