MCID: NRL016
MIFTS: 74

Neural Tube Defects malady

Genetic diseases, Rare diseases, Neuronal diseases categories

Aliases & Classifications for Neural Tube Defects

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Aliases & Descriptions for Neural Tube Defects:

Name: Neural Tube Defects 49 32 11 45 22 47 24 35 67
Spina Bifida 49 32 10 45 22 23 46 47 12 35 2 67
Spinal Dysraphism 45 23
Rachischisis 45 23
Cleft Spine 45 23
 
Open Spine 45 23
Ntds 45 22
Anencephaly 22
Dysraphism 45
Ntd 67


Classifications:



External Ids:

OMIM49 182940
Disease Ontology10 DOID:0080016
ICD1027 Q05, Q05.4
MeSH36 D009436

Summaries for Neural Tube Defects

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NINDS:46 Spina bifida (SB) is a neural tube defect (a disorder involving incomplete development of the brain, spinal cord, and/or their protective coverings) caused by the failure of the fetus's spine to close properly during the first month of pregnancy. Infants born with SB sometimes have an open lesion on their spine where significant damage to the nerves and spinal cord has occurred. Although the spinal opening can be surgically repaired shortly after birth, the nerve damage is permanent, resulting in varying degrees of paralysis of the lower limbs. Even when there is no lesion present there may be improperly formed or missing vertebrae and accompanying nerve damage. In addition to physical and mobility difficulties, most individuals have some form of learning disability. The types of SB are: myelomeningocele, the severest form, in which the spinal cord and its protective covering (the meninges) protrude from an opening in the spine; meningocele in which the spinal cord develops normally but the meninges and spinal fluid) protrude from a spinal opening; closed neural tube defects, which consist of a group of defects in which development of the spinal cord is affected by malformations of the fat, bone, or meninges; and and occulta, the mildest form, in which one or more vertebrae are malformed and covered by a layer of skin. SB may also cause bowel and bladder complications, and many children with SB have hydrocephalus (excessive accumulation of cerebrospinal fluid in the brain).

MalaCards based summary: Neural Tube Defects, also known as spina bifida, is related to neural tube defects, folate-sensitive and lumbosacral spina bifida cystica, and has symptoms including autosomal dominant inheritance, urinary incontinence and hydrocephalus. An important gene associated with Neural Tube Defects is CCL2 (Chemokine (C-C Motif) Ligand 2), and among its related pathways are Defective MTR causes methylmalonic aciduria and homocystinuria type cblG and Folate-Alcohol and Cancer Pathway. Affiliated tissues include brain, spinal cord and bone, and related mouse phenotypes are pigmentation and hearing/vestibular/ear.

NIH Rare Diseases:45 Neural tube defects (ntds) refers to a group of abnormalities resulting from abnormal development of the brain, spine and/or spinal column. during the development of an affected embryo, a structure called the neural tube does not close completely as it should, resulting in a hole somewhere along the spinal column. specific examples of types of ntds include spina bifida, anencephaly, and encephalocele. symptoms vary depending on the type of ntd present but often include various forms of physical and/or mental disabilities. many affected individuals do not survive. the exact cause of ntds is not known but is thought to involve both genetic and nongenetic factors. getting enough folic acid before and during pregnancy can reduce the risk of some ntds. treatment depends on the severity and type of defect and may include surgery. last updated: 11/6/2013

MedlinePlus:35 Neural tube defects are birth defects of the brain, spine, or spinal cord. they happen in the first month of pregnancy, often before a woman even knows that she is pregnant. the two most common neural tube defects are spina bifida and anencephaly. in spina bifida, the fetal spinal column doesn't close completely. there is usually nerve damage that causes at least some paralysis of the legs. in anencephaly, most of the brain and skull do not develop. babies with anencephaly are usually either stillborn or die shortly after birth. another type of defect, chiari malformation, causes the brain tissue to extend into the spinal canal. the exact causes of neural tube defects aren't known. you're at greater risk of having an infant with a neural tube defect if you are obese have poorly controlled diabetes take certain antiseizure medicines getting enough folic acid, a type of b vitamin, before and during pregnancy prevents most neural tube defects. neural tube defects are usually diagnosed before the infant is born, through lab or imaging tests. there is no cure for neural tube defects. the nerve damage and loss of function that are present at birth are usually permanent. however, a variety of treatments can sometimes prevent further damage and help with complications. nih: national institute of child health and human development

CDC:2 Spina bifida is a major birth defect of a person’s spine. With good quality medical care people with spina bifida can reach their full potential. If you have spina bifida, or know someone who does, it’s important to get the facts so that you can make the best possible health care choices.

Genetics Home Reference:23 Spina bifida is a condition in which the neural tube, a layer of cells that ultimately develops into the brain and spinal cord, fails to close completely during the first few weeks of embryonic development. As a result, when the spine forms, the bones of the spinal column do not close completely around the developing nerves of the spinal cord. Part of the spinal cord may stick out through an opening in the spine, leading to permanent nerve damage. Because spina bifida is caused by abnormalities of the neural tube, it is classified as a neural tube defect.

OMIM:49 Neural tube defects are the second most common type of birth defect after congenital heart defects. The 2 most common... (182940) more...

UniProtKB/Swiss-Prot:67 Neural tube defects: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy. Failure of neural tube closure can occur at any level of the embryonic axis. Common NTD forms include anencephaly, myelomeningocele and spina bifida, which result from the failure of fusion in the cranial and spinal region of the neural tube. NTDs have a multifactorial etiology encompassing both genetic and environmental components.

Related Diseases for Neural Tube Defects

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Diseases related to Neural Tube Defects via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 399)
idRelated DiseaseScoreTop Affiliating Genes
1neural tube defects, folate-sensitive31.6MTHFD1, MTHFR, MTR, MTRR
2lumbosacral spina bifida cystica31.2FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
3cervical spina bifida aperta31.2FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
4caudal regression syndrome31.2FUZ, VANGL1
5cervicothoracic spina bifida cystica31.1FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
6thoracolumbosacral spina bifida cystica31.1FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
7total spina bifida cystica31.1FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
8upper thoracic spina bifida aperta31.1FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
9cervicothoracic spina bifida aperta31.1FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
10vangl2-related neural tube defect30.9CCL2, VANGL1
11amnestic disorder30.8CBS, MTHFR, MTR, MTRR
12craniosynostosis30.8CELSR1, DACT1, SCRIB, VANGL2
13cranial meningocele30.7FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
14occipital encephalocele30.7FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
15open iniencephaly30.4FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
16closed iniencephaly30.4FUZ, MTHFD1, MTHFR, T, VANGL1, VANGL2
17spina bifida aperta11.1
18anencephaly10.8
19cerebritis10.7
20neurogenic bladder10.7
21split hand urinary anomalies spina bifida10.7
22encephalocele10.6
23bladder disease10.6
24cervicitis10.6
25fecal incontinence10.6
26anencephaly and spina bifida x-linked10.6
27down syndrome10.6
28omphalocele10.6
29cerebral palsy10.5
30spinal cord injury10.5
31spondylolisthesis10.5
32constipation10.5
33scoliosis10.5
34orofacial cleft10.5
35exencephaly10.5
36iniencephaly10.5
37basal cell nevus syndrome10.5
38spondylolysis10.5
39neurogenic bowel10.5
40chiari malformation type 210.5
41cervical spina bifida cystica10.5
42obesity10.4
43hydrocephalus10.4
44familial benign flecked retina10.4MTHFR, VANGL2
45laron syndrome with immunodeficiency10.4MTR, MTRR
46y-linked disease10.4MTR, MTRR
47congenital intrinsic factor deficiency10.4MTR, MTRR
48homocystinuria due to mthfr deficiency10.4MTHFR, MTR
49neu-laxova syndrome110.4
50peters anomaly10.4

Graphical network of the top 20 diseases related to Neural Tube Defects:



Diseases related to neural tube defects

Symptoms for Neural Tube Defects

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Symptoms by clinical synopsis from OMIM:

182940

Clinical features from OMIM:

182940

HPO human phenotypes related to Neural Tube Defects:

(show all 8)
id Description Frequency HPO Source Accession
1 autosomal dominant inheritance HP:0000006
2 urinary incontinence HP:0000020
3 hydrocephalus HP:0000238
4 multiple lipomas HP:0001012
5 anencephaly HP:0002323
6 myelomeningocele HP:0002475
7 spina bifida occulta HP:0003298
8 asymmetry of spinal facet joints HP:0008482

Drugs & Therapeutics for Neural Tube Defects

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Drugs for Neural Tube Defects (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 85)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
ChlorhexidineapprovedPhase 436455-56-19552079, 2713
Synonyms:
1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide)
1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide
1,6-Bis(5-(p-chlorophenyl)biguandino)hexane
1,6-Bis(p-chlorophenyldiguanido)hexane
1,6-Di(4'-chlorophenyldiguanido)hexane
1,6-Di(N-p-chlorophenyldiguanido)hexane
24798_FLUKA
282227_ALDRICH
348031_ALDRICH
4-12-00-01201 (Beilstein Handbook Reference)
55-56-1
AB00053427
AB1003159
AVAGARD
BPBio1_000272
BRN 2826432
BSPBio_000246
BSPBio_001977
Betasept
C06902
C22H30Cl2N10
CAS-55-56-1
CCRIS 9230
CHEBI:3614
CHEMBL790
CID9552079
Chlorhexidin
Chlorhexidin [Czech]
Chlorhexidine
Chlorhexidine (INN)
Chlorhexidine Base
Chlorhexidine Gluconate
Chlorhexidine [INN:BAN]
Chlorhexidine gluconate
Chlorhexidinum
Chlorhexidinum [INN-Latin]
Cloresidina
Cloresidina [DCIT]
Clorhexidina
Clorhexidina [INN-Spanish]
D07668
DB00878
Decanoylacetaldehyde Sodium Sulfide
Dentisept [veterinary]
Dentisept [veterinary] (TN)
DivK1c_000761
EINECS 200-238-7
Fimeil
HMS1568M08
HSDB 7196
Hexadol
Hibiclens
Hibispray
Hibistat
I06-0621
I14-0050
IDI1_000761
KBio1_000761
 
KBio2_000717
KBio2_003285
KBio2_005853
KBio3_001197
KBioGR_000774
KBioSS_000717
LS-43917
Lisium (*Dihydrochloride*)
MK-412A
MLS001332387
MLS001332388
MLS002154209
Merfen-incolore
Merfen-incolore (TN)
MolPort-002-541-741
N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca- nediimidamide
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
NCGC00016246-01
NCGC00091025-01
NCGC00091025-02
NINDS_000761
NSC526936
Nolvasan
Nolvasan (*Diacetate*)
Novalsan
Oro-Clense
Paroex
Perichlor
Peridex
Periochip
Periogard
Prestwick0_000143
Prestwick1_000143
Prestwick2_000143
Prestwick3_000143
Prestwick_53
QTL1_000020
Rotersept
SMR000857146
SPBio_000210
SPBio_002185
STK089248
STOCK1S-18831
Savloclens
Savlon babycare
Sebidin A
Sodium Houttuyfonamide
Soretol
Spectrum2_000135
Spectrum3_000339
Spectrum4_000277
Spectrum5_001322
Spectrum_000237
Sterido
Sterilon
Superspray
Tubulicid
UNII-R4KO0DY52L
chlorhexidine
2
Oxybutyninapproved, investigationalPhase 4, Phase 3625633-20-54634
Synonyms:
1508-65-2 (hydrochloride)
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
4-(diethylamino)-2-butynyl-alpha-cyclohexyl-alpha-hydroxybenzeneacetate
4-(diethylamino)-2-butynyl-alpha-phenylcyclohexaneglycolate
4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
4-(diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate
4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
5633-20-5
AC-2153
AC1L1ILV
BPBio1_000214
BRD-A65013509-003-03-8
BSPBio_000194
Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
C07360
CCRIS 1923
CHEBI:7856
CHEMBL1231
CID4634
Cyclohexaneglycolic acid, .alpha.-phenyl-, 4-(diethylamino)-2-butynyl ester
Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
Cystrin
D00465
DB01062
Ditropan
Ditropan, Lyrinel XL, Oxytrol, Oxybutynin
FT-0082890
Gelnique
HSDB 3270
I06-2117
L000923
LS-28714
 
Lopac0_000923
MolPort-003-849-741
NCGC00015767-06
NCGC00089795-02
Oxibutinina
Oxibutinina [INN-Spanish]
Oxibutyninum
Oxybutinin
Oxybutynin
Oxybutynin (USAN/INN)
Oxybutynin Base
Oxybutynin Chloride
Oxybutynin Hydrochloride
Oxybutynin [USAN:INN:BAN]
Oxybutynin topical gel
Oxybutynine
Oxybutynine [INN-French]
Oxybutyninum
Oxybutyninum [INN-Latin]
Oxytrol
Oxytrol (TN)
Oxytrol For Women
Pollakisu
Prestwick0_000287
Prestwick1_000287
Prestwick2_000287
Prestwick3_000287
S1754_Selleck
SPBio_002413
Transdermal patch
UNII-K9P6MC7092
oxybutynin
oxybutynin topical gel
transdermal patch
3Botulinum Toxins, Type APhase 4, Phase 3561
4Botulinum ToxinsPhase 4, Phase 3590
5Mandelic AcidsPhase 423
6DisinfectantsPhase 4376
7Chlorhexidine gluconatePhase 4364
8
HydroxocobalaminapprovedPhase 321713422-51-011953898, 5460373, 44475014
Synonyms:
13422-51-0
22465-48-1
78091-12-0
8017-22-9
Acti-B12
AlphaRedisol
AlphaRedisol (TN)
Axion
Axlon
Benzimidazolyl ribofuranosyl phosphate deriv.
C08230
C62H85CoN13O15P
CHEBI:27786
CHEMBL1200742
CHEMBL235822
CID11622291
CID11953898
CID5460373
CID6433575
CID6474319
Ciplamin H
Coalpha-[alpha-(5,6-dimethylbenzimidazolyl)]-Cobeta-hydroxocobamide
Cobalex
Cobalin H
Cobinamide dihydroxide dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-a-D-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole inner salt
Cobinamide hydroxide phosphate 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosylbenzimidazole inner salt
Cobinamide, Co-hydroxy-, dihydrogen phosphate (ester), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, Co-hydroxy-, f-(dihydrogen phosphate), inner salt, 3'-ester with (5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole-kappaN3)
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono (inner salt), 3'- ester with 5,6-dimethyl-1-alpha-D-ribofuranosylbenzimidazole
Cobinamide, dihydroxide, dihydrogen phosphate (ester), mono(inner salt), 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Cobinamide, hydroxide, dihydrogen phosphate (ester), inner salt, 3'-ester with 5,6-dimethyl-1-alpha-D-ribofuranosyl-1H-benzimidazole
Codroxomin
Cyanokit
Cyanokit (TN)
D01027
DB00200
Depogamma
Docclan
Docelan
Docelvita
Docevita
Droxomin
Ducobee Hy
Ducobee-Hy
Duradoce
Duralta-12
EINECS 236-533-2
HSDB 3342
HYDROXOCOBALAMIN
Hidroxocobalamina
Hidroxocobalamina [INN-Spanish]
 
Hydro Cobex
Hydrobamine
Hydrocobalamin
Hydrogrisevit
Hydrovit
Hydroxocobalamin
Hydroxocobalamin (JAN/USP/INN)
Hydroxocobalamin Vitamin B12
Hydroxocobalamin [USAN:INN:BAN:JAN]
Hydroxocobalamin acetate
Hydroxocobalamin monohydrochloride
Hydroxocobalamin(alkaline soln.), OH- replaces CN- in Cyanocobalamin)
Hydroxocobalaminacetat
Hydroxocobalamine
Hydroxocobalamine [INN-French]
Hydroxocobalaminum
Hydroxocobalaminum [INN-Latin]
Hydroxocobemine
Hydroxomin
Hydroxy Cobal
Hydroxy vitamin B12
Hydroxycob(lll)alamin
Hydroxycobalamin
Hydroxycobalamine
Hyxobamine
Idrogrisevit
Idrossocobalamina
Idrossocobalamina [DCIT]
LS-54607
Lyovit-H
Neo-Betalin 12
Neo-cytamen
Neo-macrabin
Neo-rojamin
OH-Cbl
OH-Duphar
Ohb12
Oxobemin
Oxolamine (arcum)
Primabalt RP
Redisol-H
S1668_Selleck
Sytobex-H
UNII-Q40X8H422O
Vibeden
Vitadurin
Vitamin B(sub 12a)
Vitamin B-12b
Vitamin B12a
Vitamin B12b
a-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
alpha Cobione
alpha-(5,6-Dimethylbenzimidazolyl)hydroxocobamide
vitamin B-12b
9
SolifenacinapprovedPhase 3103242478-37-1216457
Synonyms:
1-azabicyclo[2.2.2]oct-8-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
1-azabicyclo[2.2.2]octan-3-yl (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-1-phenyl-, (3R)-1-azabicyclo(2.2.2)oct-3-yl ester, (1S)-, butanedioate (1:1)
242478-37-1
242478-38-2
AC1L4BM3
AC1L50Q6
AC1L9FFR
AC1Q5VRD
AR-1L5425
Butanedioic acid, cmpd. with (1S)-(3R)-1-azabicyclo(2.2.2)oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
Butanedioic acid, compd with (1S)-(3R)-1-azabicyclo(2.2.2)oct-3-yl 3,4-dihydro-1-phenyl-2(1H)-isoquinolinecarboxylate (1:1)
CHEMBL1200803
CHEMBL1734
CID154059
CID216457
CID443938
D08522
DB01591
 
LS-183550
MolPort-003-850-268
NCGC00168778-01
Quinuclidin-3'-yl-1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylatemonosuccinate
Solifenacin
Solifenacin (INN)
Solifenacin [INN:BAN]
Solifenacin succinate
Solifenacin succinate [USAN]
UNII-A8910SQJ1U
UNII-KKA5DLD701
Vesicare
Vesikur
YM 905
YM-53705
YM-67905
YM-905
[(3R)-1-azabicyclo[2.2.2]octan-3-yl] (1S)-1-phenyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
butanedioic acid
solifenacin succinate
10
Estradiolapproved, investigationalPhase 3105750-28-25757, 53477783
Synonyms:
(+)-3,17b-Estradiol
(17b)-Estra-1,3,5(10)-triene-3,17-diol
(17beta)-Estra-1,3,5(10)-triene-3,17-diol
.alpha.-Estradiol
.alpha.-Oestradiol
.beta.-Estradiol
.beta.-Oestradiol
1,3,5[10]-Estratriene-3,17beta-diol 3-sulfate
1,3,5[10]-Estratriene-3,17beta-diol 3-sulphate
13b-Methyl-1,3,5(10)-gonatriene-3,17b-ol
17 beta-Estradiol
17-.BETA.-Estradiol
17-E
17-beta
17-beta-OH-estradiol
17-beta-estradiol
17.beta.-Estradiol
17.beta.-Oestradiol
17E
17b-Estradiol
17b-Oestradiol
17beta Oestradiol
17beta oestradiol
17beta-Estra-1,3,5(10)-triene-3,17-diol
17beta-Estradiol
17beta-Oestradiol
1jgl
1qkt
1qku
2d06
3,17-Epidihydroxyestratriene
3,17-beta-Estradiol
3,17-beta-Oestradiol
3,17.beta.-Estradiol
3,17b-Dihydroxyestra-1,3,5(10)-triene
3,17b-Estradiol
3,17beta-Estradiol
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulfate
3,17beta-dihydroxy-1,3,5[10]-estratriene 3-sulphate
50-28-2
73459-61-7
873662-39-6
AC-10460
AC1L1L2K
Aerodiol
Agofollin
Alora
Altrad
Amnestrogen
Aquadiol
B-Estradiol
BEDOs
BIDD:ER0125
BIDD:PXR0065
BPBio1_000532
BSPBio_000482
BSPBio_001065
Bardiol
Benzhormovarine
Beta-estradiol
Bio-0812
Bio-E-Gel
Bio1_000403
Bio1_000892
Bio1_001381
Bio2_000363
Bio2_000843
C00951
C18H24O2
CCRIS 280
CHEBI:16469
CHEMBL135
CID5757
CMC_11154
CPD-352
CPD000059126
Climaderm
Climara
Climara (TN)
Climara Forte
Compudose
Compudose 200
Compudose 365
Corpagen
D-3,17beta-Estradiol
D-Estradiol
D-Oestradiol
D00105
DB00783
Depo-estradiol
Dermestril
Destradiol
Dihydro-Theelin
Dihydrofollicular hormone
Dihydrofolliculin
Dihydromenformon
Dihydrotheelin
Dihydroxyesterin
Dihydroxyestrin
Dihydroxyoestrin
Dimenformon
Diogyn
Diogynets
Divigel
Divigel (TN)
E 2
E 8875
E(sub 2)
E0025
E1024_SIGMA
E1132_SIGMA
E2257_SIGMA
E2758_SIGMA
E8875_SIGMA
EINECS 200-023-8
EU-0100503
Elestrin
Encore
Epiestriol 50
Esclim
Estra-1,3,5(10)-triene-3,17b-diol
Estrace
Estrace (TN)
Estraderm
Estraderm (TN)
Estraderm MX
Estraderm TTS
Estraderm TTS 100
Estraderm TTS 50
Estradiol
Estradiol Transdermal System
Estradiol Valerate
Estradiol [USAN:INN]
Estradiol acetate
Estradiol benzoate
Estradiol cypionate
Estradiol valerate
Estradiol-17 beta
Estradiol-17-beta
Estradiol-17.beta.
Estradiol-17beta
Estradiol-3,17beta
Estradiolo
Estradiolo [DCIT]
Estradiolum
Estradiolum [INN]
Estradot
Estraldine
Estrapak 50
Estrasorb
Estrasorb (TN)
Estreva
Estrifam
Estring
Estring (TN)
Estring Vaginal Ring
Estring vaginal ring
Estroclim
Estroclim 50
Estrodiolum
Estrofem 2
 
Estrofem Forte
Estrogel
Estrogel (TN)
Estrogel HBF
Estrovite
Evamist
Evorel
Extrasorb
Femanest
Femestral
Femestrol
Femogen
Fempatch
Femring
Femtrace
Femtran
Follicyclin
Gelestra
Ginedisc
Ginosedol
GynPolar
Gynergon
Gynestrel
Gynodiol
Gynoestryl
HMS1362E07
HMS1569I04
HMS1792E07
HMS1990E07
HMS2051C17
HMS2090E18
HSDB 3589
IDI1_002118
Innofem
Innofem (TN)
KBio2_000405
KBio2_002269
KBio2_002973
KBio2_004837
KBio2_005541
KBio2_007405
KBio3_000769
KBio3_000770
KBio3_002749
KBioGR_000405
KBioGR_002269
KBioSS_000405
KBioSS_002270
LMST02010001
LS-137
Lamdiol
Lio-Oid
Lopac0_000503
MLS000069494
MLS000758312
MLS001076331
Macrodiol
Macrol
Menest
Menorest
Menostar
Microdiol
Minivelle
MolPort-001-794-632
NCGC00091544-00
NCGC00091544-01
NCGC00091544-02
NCGC00091544-04
NCGC00091544-05
NCGC00091544-06
NCGC00091544-07
NCGC00091544-08
NCGC00091544-09
NCGC00091544-12
NCGC00179321-01
NCGC00179321-02
NSC-9895
NSC9895
Nordicol
Oesclim
Oestergon
Oestra-1,3,5(10)-triene-3,17b-diol
Oestradiol
Oestradiol Berco
Oestradiol R
Oestradiol-17-beta
Oestradiol-17.beta.
Oestradiol-17beta
Oestradiolum
Oestrogel
Oestroglandol
Oestrogynal
Ovahormon
Ovasterol
Ovastevol
Ovociclina
Ovocyclin
Ovocycline
Ovocylin
Perlatanol
Polyestradiol
Prestwick0_000441
Prestwick1_000441
Prestwick2_000441
Prestwick3_000441
Prestwick_207
Primofol
Profoliol
Profoliol B
Progynon
Progynon DH
Progynon-DH
S-21400
S1709_Selleck
SAM001247032
SK-Estrogens
SL-1100
SMP1_000121
SMR000059126
SPBio_002421
Sandrena 1
Sandrena Gel
Sisare Gel
Spectrum5_002055
Syndiol
Systen
Tradelia
Trial SAT
Trocosone
UNII-4TI98Z838E
VIVELLE-DOT
Vagifem
Vagifem (TN)
Vivelle
Vivelle (TN)
Vivelle Dot
Vivelle-dot
Zerella
Zesteem
Zesteen
Zumenon
[2,4,6,7-3H]-E2
[3H]-estradiol
[3H]]estradiol
b-Estradiol
beta-Estradiol
beta-Estradiol 3-sulfate
beta-Estradiol 3-sulphate
bmse000642
cMAP_000005
cis-Estradiol
cis-Oestradiol
component of Menrium
delta-Estradiol
delta-Oestradiol
estradiol
estradiol-17beta
nchembio.168-comp3
nchembio.76-comp2
nchembio775-comp2
nchembio794-comp6
nchembio860-comp1
progynon
11
Ethinyl EstradiolapprovedPhase 363657-63-65991
Synonyms:
17 alpha-Ethinylestradiol
17 alpha-Ethynylestradiol
17 alpha-Ethynyloestradiol
17 alpha-ethinyestradiol
17-Ethinyl-3,17-estradiol
17-Ethinyl-3,17-oestradiol
17-Ethinylestradiol
17-Ethynylestradiol
17-Ethynylestradiol ram
17-Ethynyloestradiol
17-alpha-Ethinyl-17-beta-estradiol
17-alpha-Ethynyl-17-beta-oestradiol
17-alpha-Ethynylestradiol
17-alpha-Ethynylestradiol-17-beta
17-alpha-ethynyl estradiol
17-ethinyl-3,17-estradiol
17-ethinyl-3,17-oestradiol
17-ethinylestradiol
17.alpha.-Ethinyl-17.beta.-estradiol
17.alpha.-Ethinylestradiol
17.alpha.-Ethynyl-17.beta.-oestradiol
17.alpha.-Ethynylestradiol
17.alpha.-Ethynylestradiol-l7.beta.
17.alpha.-Ethynyloestradiol
17.alpha.-Ethynyloestradiol-17.beta.
17a-Ethinyl-17b-estradiol
17a-Ethinylestradiol
17a-Ethynyl-17b-oestradiol
17a-Ethynylestradiol
17a-Ethynylestradiol-l7b
17a-Ethynyloestradiol
17a-Ethynyloestradiol-17b
17alpha-Ethinyl estradiol
17alpha-Ethinylestradiol
17alpha-Ethinylestradiol-17beta
17alpha-Ethynylestradiol
17alpha-Ethynyloestradiol
17alpha-Ethynyloestradiol-17beta
17α-ethynylestradiol
406932-93-2
46263_FLUKA
46263_RIEDEL
57-63-6
77538-56-8
AC-2169
AC1L1LK6
AI3-52941
Aethinyloestradiolum
Aethinyoestradiol
Aethinyoestradiol [German]
Alora
Amenoron
Amenorone
Anovlar
BIDD:ER0162
BRN 2419975
Bio-0610
C07534
CCRIS 286
CHEBI:4903
CHEMBL691
CID5991
CPD000058319
Certostat
Chee-O-Gen
Chee-O-Genf
Cyclosa
D004997
D00554
DB00977
Dicromil
Diognat-E
Diogyn E
Diogyn-E
Diprol
Dyloform
E4876_SIGMA
EE
EE(sub 2)
EE2
EINECS 200-342-2
EO
ETHINYLESTRADIOL
Effik Brand of Ethinyl Estradiol
Ertonyl
Esclim
Esteed
Estigyn
Estinyl
Estinyl (TN)
Eston-E
Estopherol
Estoral
Estoral (Orion)
Estoral (VAN)
Estoral [Orion]
Estoral {[Orion]}
Estorals
Estradiol, Ethinyl
Estradiol, Ethynyl
Estring
Estrogen
Ethidol
Ethinoral
Ethinyl E2
Ethinyl Estradiol Hemihydrate
Ethinyl Estradiol [USP]
 
Ethinyl Estradiol, (8 alpha)-Isomer
Ethinyl Oestradiol Effik
Ethinyl estradiol
Ethinyl estradiol (USP)
Ethinyl-Oestradiol Effik
Ethinyl-Oestranol
Ethinyl-oestranol
Ethinylestradiol
Ethinylestradiol (JP15/INN)
Ethinylestradiol Jenapharm
Ethinylestradiol [INN:BAN:JAN]
Ethinylestradiolum
Ethinylestradiolum [INN-Latin]
Ethinylestriol
Ethinyloestradiol
Ethinyloestradiol [Steroidal oestrogens]
Ethy 11
Ethynyl estradiol
Ethynylestradiol
Ethynylestradiol, Ethinyl Estradiol
Ethynyloestradiol
Eticyclin
Eticyclol
Eticylol
Etinestrol
Etinestryl
Etinilestradiol
Etinilestradiol [INN-Spanish]
Etinilestradiolo
Etinilestradiolo [DCIT]
Etinoestryl
Etistradiol
Etivex
Evra
Feminone
Fempatch
Follicoral
Ginestrene
Gynodiol
Gynolett
HMS2051I19
HSDB 3587
Halodrin
Hemihydrate, Ethinyl Estradiol
Inestra
Innofem
Jenapharm Brand of Ethinyl Estradiol
Jenapharm, Ethinylestradiol
Kolpolyn
LMST02010036
LS-231
Linoral
Lynoral
MLS000028479
MLS000758274
Marvelon
Menolyn
Menostar
Mercilon
Microfollin
Microfollin Forte
MolPort-001-794-636
NCGC00091533-01
NCGC00091533-04
NCGC00091533-05
NCI60_000234
NSC-10973
NSC10973
Neo-Estrone
Nogest-S
Novestrol
OVULEN-21
OVULEN-28
Oradiol
Orestralyn
Orestrayln
Organon Brand of Ethinyl Estradiol
Ortho-Cyclen
Ovex
Oviol
PUBERTAL ETHINYL ESTRADIOL STUDY
Palonyl
Perovex
Primogyn
Primogyn C
Primogyn M
Progynon C
Progynon M
Prosexol
S1625_Selleck
SAM001247008
SGCUT00127
SMR000058319
Schering Brand of Ethinyl Estradiol
Spanestrin
Thiuram E
Thiuranide
UNII-423D2T571U
Vagifem
Varnoline
WLN: L E5 B666TTT&J E1 FQ F1UU1 OQ
Ylestrol
component of Demulen
component of Oracon
component of Ortrel
ethinyl estradiol
ethynyl estradiol
to_000048
12
DrospirenoneapprovedPhase 38767392-87-468873
Synonyms:
(6R,7R,8R,9S,10R,13S,14S,15S,16S,17S)-1,3',4',6,6a,7,8,9,10,11,12,13,14,15,15a,16-Hexadecahydro-10,13-dimethylspiro-(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione
1, 2-Dihydrospirorenone
1,2-Dihydrospirorenone
1,2-dihydro-spirorenone
15,16]-17alpha-pregn-4-ene-21,17-carbolactone
15-beta,16-beta-Dimethylene-3-oxo-17-alpha-pregn-4-ene-21,17-carbolactone
15beta,16beta-Dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
17-Hydroxy-6beta,7beta:15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21-carboxylic acid, gamma-lactone
3-oxo-6alpha,7alpha,15alpha,16alpha-tetrahydro-7'H,16'H-dicyclopropa[6,7
6-beta,7-beta
67392-87-4
6beta,7Beta
6beta,7beta
6beta,7beta,15beta,16beta-dimethylen-3-oxo-17alpha-pregn-4-en-21,17-carbolacton
6beta,7beta,15beta,16beta-dimethylene-3-oxo-17alpha-pregn-4-ene-21,17 carbolactone
6β,7β,15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17 carbolactone
AC1L2AMM
Angeliq, Drospirenone
BRN 4765500
C035144
C24H30O3
CCRIS 6523
CHEBI:50838
CHEMBL1509
CID68873
 
D03917
DB01395
DRSP
Dehydrospirorenone
Dihydrospirorenone
Drospirenona
Drospirenona [INN-Spanish]
Drospirenona [inn-spanish]
Drospirenone
Drospirenone (JAN/USAN/INN)
Drospirenone [INN]
Drospirenonum
Drospirenonum [INN-Latin]
Drospirenonum [inn-latin]
EINECS 266-679-2
LS-146115
S1377_Selleck
SH-470
Safyral
Spiro(17H-dicyclopropa(6,7:15,16)cyclopenta(a)phenanthrene-17,2'(5'H)-furan)-3,5'(2H)-dione, 1,3',4',6,7,8,9,10,11,12,13,14,15,16,20,21-hexadecahydro-10,13-dimethyl-, (6R-(6alpha,7alpha,8beta,9alpha,10beta,13beta,14alpha,15alpha,16alpha,17beta
UNII-N295J34A25
Yasmin
Yaz
ZINC03927200
ZK 30595
ZK-30595
ZK30595
13
IronapprovedPhase 39577439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
14
ZincapprovedPhase 314047440-66-623994, 32051
Synonyms:
30Zn
Cinc
Zinc
Zinc ion
 
Zincum
Zink
Zn
Zn(ii)
Zn2+
15
Folic Acidapproved, nutraceuticalPhase 3, Phase 1285159-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
16
Cyanocobalaminapproved, nutraceuticalPhase 321768-19-944176380, 44176380, 5462245
Synonyms:
Anacobin
Bedoz
Berocca PN
Berubigen
Betalin 12
Betalin 12 Crystalline
Betaline-12
Betolvex
Bevidox
Bevidox concentrate
Biocobalamine
Byladoce
Cabadon m
Cernevit-12
Cobadoce forte
Cobalin
Cobavite
Cobex
Cobolin-M
Copharvit 5000
Covit
Crystamin
Crystamine
Crysti-12
Crystimin
Crystwel
Cyano-B12
Cyanobalamin concentrate
Cyanocob(III)alamin
Cyanocobalamin
Cyanocobalamin (JP15/USP)
Cyanocobalamin Co 57 Schilling Test Kit
Cyanocobalamine
Cyanocobalmin
Cyanoject
Cycobemin
Cycolamin
Cykobemin
Cykobeminet
Cyomin
Cyredin
Cytacon
Cytamen
Cytobion
Depinar
Dicopac
Dicopac Kit
Dimethylbenzimidazoylcobamide
Distivit
Docemine
Docibin
Docivit
Dodecabee
Dodecavite
Dodex
Duodecibin
Embiol
Emociclina
Eritrone
 
Erycytol
Erythrotin
Euhaemon
Extrinsic factor
Factor II
Fermin
Fresmin
Hemomin
Hepagon
Hepavis
Hepcovite
Hylugel plus
Infuvite Pediatric
Lactobacillus lactis dorner factor
M.V.I. Pediatric
Macrabin
Megabion
Megalovel
Milbedoce
Millevit
Nagravon
Nascobal
Nascobal (TN)
Neuroforte-R
Normocytin
Novidroxin
Pernaemon
Pernaevit
Pernipuron
Plecyamin
Poyamin
Primabalt
Rebramin
Redamina
Redisol
Rhodacryst
Rubesol
Rubivite
Rubramin
Rubramin PC
Rubratope-57 Kit
Rubratope-60 Kit
Rubripca
Rubrocitol
Ruvite
Shovite
Sytobex
Vi-Twel
Vibal
Vibalt
Vibisone
Virubra
Vita-rubra
Vitabee 12
Vitamin B12
Vitamin B12 Preparation
Vitamin B12 complex
Vitaped
Vitarubin
Vitral
vitamine b12
17
Niacinapproved, investigational, nutraceuticalPhase 334059-67-6938
Synonyms:
3-Carboxylpyridine
3-Carboxypyridine
3-Pyridinecarboxylate
3-Pyridinecarboxylic acid
3-Pyridylcarboxylate
3-Pyridylcarboxylic acid
3-carboxypyridine
Acide Nicotinique
Acido nicotinico
Acidum Nicotinicum
Akotin
Anti-pellagra vitamin
Apelagrin
Daskil
Efacin
Enduracin
Linic
M-Pyridinecarboxylic Acid
Niac
Niacin
Niacine
Niacor
Niaspan
Niaspan ER
Nicacid
Nicamin
 
Nicangin
Nico-Span
Nicobid
Nicocap
Nicodelmine
Nicolar
Niconacid
Nicosan 3
Nicotinate
Nicotinic Acid
Nicotinic acid
Nicotinipca
Nicyl
Nikotinsaeure
Nyclin
P.P. factor
PP Factor
Pellagra preventive factor
Pellagrin
Pelonin
Pyridine-beta-carboxylic acid
Slo-niacin
Vitamin B3
Wampocap
beta-Pyridinecarboxylic acid
pyridine-β-carboxylic acid
β-pyridinecarboxylic acid
18
Vitamin Capproved, nutraceuticalPhase 339850-81-75785, 54670067
Synonyms:
(+)-Sodium L-ascorbate
(+)-ascorbate
(+)-ascorbic acid
(2R)-2-[(1S)-1,2-Dihydroxyethyl]-4,5-dihydroxy-furan-3-one
(2R)-2-[(1S)-1,2-dihydroxyethyl]-4,5-dihydroxyfuran-3-one
(5R)-5-[(1S)-1,2-dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
129940-97-2
134-03-2 (monosodium salt)
14536-17-5
154170-90-8
2-(1,2-Dihydroxyethyl)-4,5-dihydroxyfuran-3-one
255564_SIAL
259133-78-3
3-Keto-L-gulofuranolactone
3-Oxo-L-gulofuranolactone
3-Oxo-L-gulofuranolactone (enol form)
30208-61-8
33034_RIEDEL
33034_SIAL
47863_SUPELCO
47A605F0-4187-47A8-B0CE-F9E7DA1B0076
50-81-7
50976-75-5
56172-55-5
56533-05-2
57304-74-2
57606-40-3
623158-95-2
6730-29-6
882690-91-7
884381-69-5
885512-24-3
88845-26-5
89924-69-6
95209_FLUKA
95209_SIGMA
95210_FLUKA
95210_SIAL
95212_FLUKA
A0278_SIGMA
A0537
A2174_SIGMA
A2218_SIGMA
A2343_SIGMA
A4403_SIGMA
A4544_SIGMA
A5960_SIGMA
A7506_SIGMA
A92902_ALDRICH
A92902_SIAL
AA
AB00376923
AB1002440
AC1L1L4T
AC1Q77S6
AR-1J3435
Acid Ascorbic
Acide ascorbique
Acide ascorbique [INN-French]
Acido ascorbico
Acido ascorbico [INN-Spanish]
Acidum ascorbicum
Acidum ascorbicum [INN-Latin]
Acidum ascorbinicum
Adenex
Allercorb
Ambap36431-82-0
Antiscorbic Vitamin
Antiscorbic vitamin
Antiscorbutic Vitamin
Antiscorbutic factor
Antiscorbutic vitamin
Arco-Cee
Arco-cee
Ascoltin
Ascoltin (TN)
Ascor-B.I.D.
Ascorb
Ascorbajen
Ascorbate
Ascorbic Acid
Ascorbic Acid, Monosodium Salt
Ascorbic acid
Ascorbic acid (JP15/USP/INN)
Ascorbic acid [BAN:INN:JAN]
Ascorbic acid [INN:BAN:JAN]
Ascorbicab
Ascorbicap
Ascorbicap (TN)
Ascorbicin
Ascorbin
Ascorbinsaeure
Ascorbutina
Ascorbyl radical
Ascorin
Ascorteal
Ascorvit
BPBio1_000363
BSPBio_000329
Babor Baborganic Biological Enzyme Cleanser
C-Level
C-Long
C-Quin
C-Span
C-Vimin
C00072
C6H8O6
CCRIS 57
CE-VI-Sol
CHEBI:29073
CHEMBL196
CID5785
Cantan
Cantaxin
Caswell No. 061B
Catavin C
Ce Lent
Ce lent
Ce-Mi-Lin
Ce-mi-lin
Ce-vi-sol
Cebicure
Cebid
Cebion
Cebione
Cecon
Cee-Caps TD
Cee-Caps Td
Cee-Vite
Cee-caps TD
Cee-vite
Cegiolan
Ceglion
Ceklin
Celaskon
Celin
Cell C
Cemagyl
Cemill
Cenetone
Cenolate
Cereon
Cergona
Cescorbat
Cetamid
Cetane
Cetane-Caps TC
Cetane-Caps TD
Cetane-Caps Tc
Cetane-Caps Td
Cetane-caps TC
Cetane-caps TD
Cetebe
 
Cetemican
Cevalin
Cevatine
Cevex
Cevi-Bid
Cevi-bid
Cevimin
Cevital
Cevitamate
Cevitamic Acid
Cevitamic acid
Cevitamin
Cevitan
Cevitex
Cewin
Chewcee
Ciamin
Cipca
Citriscorb
Citrovit
Colascor
Concemin
Cortalex
D00018
DB00126
Davitamon C
Dora-C-500
Duoscorb
EINECS 200-066-2
FEMA No. 2109
Ferancee
Ferrous ascorbate
HSDB 818
HiCee
Hicee
Hybrin
IDO-C
Ido-C
Iron(II) ascorbate
Iron-ascorbic acid complexes
Juvamine
Kangbingfeng
Kyselina Askorbova
Kyselina askorbova
Kyselina askorbova [Czech]
L(+)-Ascorbate
L(+)-Ascorbic acid
L-(+)-Ascorbate
L-(+)-Ascorbic Acid
L-(+)-Ascorbic acid
L-(+)-ascorbic acid
L-3-Ketothreohexuronic acid lactone
L-3-ketothreohexuronic acid
L-Ascorbate
L-Ascorbic Acid
L-Ascorbic acid
L-Ascorbic acid, free radical form
L-Lyxoascorbate
L-Lyxoascorbic Acid
L-Lyxoascorbic acid
L-Threo-ascorbic acid
L-Threoascorbic acid
L-Xyloascorbate
L-Xyloascorbic Acid
L-Xyloascorbic acid
L-ascorbate
L-threo-Hex-2-enonic acid, gamma-lactone
L-threo-ascorbic acid
L-threo-hex-2-enono-1,4-lactone
LS-145
Laroscorbine
Lemascorb
Liqui-Cee
Liqui-cee
MLS002153776
Magnesium Ascorbicum
Magnorbin
Meri-C
Meri-c
MolPort-001-792-501
Monodehydroascorbic acid
NCGC00091517-01
NCGC00091517-02
NCGC00164357-01
NCI-C54808
NSC 33832
Natrascorb
Natrascorb injectable
Oral Vitamin C
Planavit C
Prestwick3_000325
Proscorbin
Redoxon
Ribena
Ronotec 100
Rontex 100
Roscorbic
Rovimix C
SMR001233160
Scorbacid
Scorbu C
Scorbu-C
Secorbate
Semidehydroascorbate
Sodascorbate
Sodium Ascorbate (Ascorbic Acid)
Stuartinic
Suncoat VC 40
Sunkist
Testascorbic
Tolfrinic
UNII-PQ6CK8PD0R
VASC
Vicelat
Vicin
Vicomin C
Viforcit
Viscorin
Viscorin 100M
Vitace
Vitacee
Vitacimin
Vitacin
Vitamin C
Vitamin- C
Vitamin-?C
Vitamisin
Vitascorbol
W210901_ALDRICH
Xitix
antiscorbic vita min
ascor-b.i.d
ascorbate
ascorbic acid
bmse000182
cee-caps td
cevibid
component of Cortalex
component of E and C-Level
component of Endoglobin Forte
component of Ferancee
e 300
e-300
e300
gamma-Lactone L-threo-Hex-2-enonate
gamma-Lactone L-threo-Hex-2-enonic acid
l-ascorbic acid
l-threo-hex-1-eofuranos-3-ulose
nchembio.174-comp5
nchembio.89-comp1
nchembio.92-comp2
nchembio821-comp9
roscorbi c
vitamin C
19
Vitamin Eapproved, nutraceuticalPhase 335059-02-914985
Synonyms:
(+)-a-Tocopherol
(+)-alpha-Tocopherol
(+)-alpha-tocopherol
(+)-α-tocopherol
(2R)-2,5,7,8-TETRAMETHYL-2-[(4R,8R)-4,8,12-trimethyltridecyl]chroman-6-ol
(2R)-3,4-Dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-ol
(2R,4'R,8'R)-a-Tocopherol
(2R,4'R,8'R)-alpha-Tocopherol
(2R,4'R,8'r)-alpha-tocopherol
(R,R,R)-a-Tocopherol
(R,R,R)-alpha-Tocopherol
(R,R,R)-alpha-tocopherol
(R,R,R)-α-tocopherol
5,7,8-Trimethyltocol
Amino-Opti-E
Aquasol E
D-alpha-Tocopherol
Daltose
Denamone
E-200 I.U. Softgels
 
E-Complex-600
E-Ferol
E-Vitamin succinate
Eprolin
Gordo-Vite E
Phytogermin
Phytogermine
RRR-alpha-tocopherol
RRR-alpha-tocopheryl
Tocopherol
Vitamin E
Vitamin Ea
Vitamin Plus E Softgells
Vitamin e
Vitec
a-D-Tocopherol
a-Tocopherol
alpha-Tocopherol
alpha-delta-Tocopherol
d-alpha-tocopherol
d-α-tocopherol
delta-alpha-Tocopherol
20
Riboflavinapproved, nutraceuticalPhase 313883-88-5493570
Synonyms:
(-)-Riboflavin
1-Deoxy-1-(3,4-dihydro-7,8-dimethyl-2,4-dioxobenzo[g]pteridin-10(2H)-yl)-D-ribitol
1-Deoxy-1-(7,8-dimethyl-2,4-dioxo-3,4-dihydrobenzo[g]pteridin-10(2H)-yl)pentitol
6,7-Dimethyl-9-D-ribitylisoalloxazine
6,7-Dimethyl-9-ribitylisoalloxazine
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)-Benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)benzo[g]pteridine-2,4(3H,10H)-dione
7,8-Dimethyl-10-(D-ribo-2,3,4,5-tetrahydroxypentyl)isoalloxazine
7,8-Dimethyl-10-ribitylisoalloxazine
Beflavin
Beflavine
Benzo[g]pteridine riboflavin deriv.
E 101
Flavaxin
Flavin BB
Flaxain
Food Yellow 15
Hyre
Lactobene
 
Lactoflavin
Lactoflavine
Ribipca
Ribocrisina
Riboderm
Riboflavin
Riboflavin phosphate sodium dihydrate
Riboflavina
Riboflavine
Riboflavinum
Ribosyn
Ribotone
Ribovel
Russupteridine yellow III
San Yellow B
Vitaflavine
Vitamin B2
Vitamin G
Vitasan B2
e101
21
Pyridoxineapproved, nutraceuticalPhase 315265-23-61054
Synonyms:
(5-hydroxy-4,6-dimethylpyridin-3-yl)methyl phosphate
12001-78-4
2-Methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-di(hydroxymethyl)pyridine
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin
2-Methyl-3-hydroxy-4,5-dihydroxymethyl-pyridin [German]
2-Methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-Methyl-4,5-bis(hydroxymethyl)-3-hydroxypyridine
2-methyl-3-hydroxy-4,5-bis(hydroxy-methyl) pyridine
2-methyl-3-hydroxy-4,5-dihydroxymethylpyridine
2-methyl-4,5-dimethylol-pyridin-3-ol
2B3E07D2-E4CC-4CC5-B085-6070BA01F9F0
3,4-Pyridinedimethanol, 5-hydroxy-6-methyl-, hydrochloride
3-Hydroxy-2-Picoline-4,5-dimethanol
3-Hydroxy-4,5-dihydroxymethyl-2-methylpyridine hydrochloride
3-Hydroxy-4,5-dimethylol-.alpha.-picoline hydrochloride
3-Hydroxy-4,5-dimethylol-alpha-picoline
3-Hydroxy-4,5-dimethylol-alpha-picoline hydrochloride
3-hydroxy-4,5-bis(hydroxymethyl)-2-methylpyridine
4,5-Bis(hydroxymethyl)-2-methyl-3-pyridinol
4,5-Bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride
4,5-bis(hydroxymethyl)-2-methyl-3-pyridinol hydrochloride
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol
4,5-bis(hydroxymethyl)-2-methylpyridine-3-ol
4-Deoxypyridoxine 5'-phosphate
47862_SUPELCO
5-Hydroxy-6-methyl-3,4-pyridinedicarbinol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol
5-Hydroxy-6-methyl-3,4-pyridinedimethanol hydrochloride
5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride
58-56-0
58-56-0 (HCL)
58-56-0 (hydrochloride)
65-23-6
65-23-6 (Parent)
8059-24-3
85078-23-5
AC-12024
AC-14512
AC-907/25014218
AC1L1AMH
AC1L1LMI
AC1L2XK2
AC1Q22HP
AC1Q2G66
AC1Q3F63
AI3-19016
AIDS-006784
AIDS006784
AR-1A6363
AR-1J1632
Adermin hydrochloride
Adermine
Adermine hydrochloride
Aderomine hydrochloride
Aderoxin
Aderoxine
Alestrol
BB_NC-0050
BIDD:PXR0180
BPBio1_000646
BSPBio_000586
Becilan
Beesix
Benadon
Bonasanit
C00314
C8H11NO3
CAS-58-56-0
CBDivE_015627
CCRIS 1903
CHEBI:16709
CHEBI:30961
CHEMBL1200756
CHEMBL1364
CID104817
CID1054
CID6019
CPD0-1221
Campoviton 6
Cernevit-12
D02179
D025101
D08454
DB00165
EINECS 200-386-2
EINECS 200-603-0
EINECS 232-503-8
Godabion
Gravidox
HMS1569N08
HMS2093L07
HSDB 1212
Hexa-Betalin
Hexa-Betalin (R)
Hexa-betalin (TN)
Hexabetalin
Hexabione hydrochloride
Hexavibex
 
Hexermin
Hexermine
Hexobion
Hydoxin
I02-1897
I02-2297
KST-1A8556
LS-134393
LS-187072
LS-2332
MLS001074329
MLS002153915
MolPort-002-137-856
MolPort-002-319-991
MolPort-005-933-330
NCGC00016261-01
NCGC00164317-01
NCGC00180946-01
NSC 36225
NSC36225
NSC36225 (HCL)
Nestrex
Oprea1_061614
P0561
P4722_SIAL
P5669_SIGMA
P6280_SIGMA
P8666_SIGMA
P9755_SIAL
PN
PN HCl
PYRIDOXINE HYDROCHLORIDE
PYRIDOXINE HYDROCHLORIDE, U.S.P.
Paxadon
Piridossina
Piridossina [DCIT]
Piridoxina
Piridoxina [INN-Spanish]
Prestwick0_000623
Prestwick1_000623
Prestwick2_000623
Prestwick3_000623
Prestwick_925
Pydox
Pyridipca
Pyridox
Pyridoxin
Pyridoxin hydrochloride
Pyridoxine
Pyridoxine (INN)
Pyridoxine HCl
Pyridoxine Hydrochloride
Pyridoxine Hydrochloride (B6)
Pyridoxine [INN:BAN]
Pyridoxine chloride
Pyridoxine hydrochloride
Pyridoxine hydrochloride (JP15/USP)
Pyridoxine hydrochloride [USAN:JAN]
Pyridoxine hydrogen chloride
Pyridoxine monohydrochloride
Pyridoxine, hydrochloride
Pyridoxine-HCl Microencapsulated
Pyridoxinium chloride
Pyridoxinum
Pyridoxinum [INN-Latin]
Pyridoxinum hydrochloricum
Pyridoxinum hydrochloricum (Hungarian)
Pyridoxol
Pyridoxol hydrochloride
Pyridoxol, hydrochloride
Pyridoxolum
Rodex
Rodex (R)
Rodex TD
SMP2_000230
SMR000674613
SPBio_002805
STK177324
STOCK1N-08684
Spondylonal
Tex Six T.R.
TimTec1_000657
UNII-68Y4CF58BV
UNII-KV2JZ1BI6Z
Vitamin B 6
Vitamin B6
Vitamin B6-hydrochloride
Vitamin V6
Vitamin V6 (TN)
Vitamin-?B6
Vitamin-?B6 hydrochloride
Vitaped
WLN: T6NJ B1 CQ D1Q E1Q &GH
ZINC00049154
ZINC21983293
bmse000288
c1302
component of Alestrol
nchembio.93-comp1
pyridoxine
vitamin B6
22
Thiamineapproved, nutraceuticalPhase 38259-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
HSDB 220
 
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine Hydrochloride
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
23
Pyridoxalapproved, nutraceuticalPhase 315065-22-5, 66-72-81050
Synonyms:
3-HYDROXY-5-(hydroxymethyl)-2-methylisonicotinaldehyde
 
3-Hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carboxaldehyde
Pyridoxal
Pyridoxaldehyde
24
Vitamin Aapproved, nutraceuticalPhase 338611103-57-4, 68-26-8445354
Synonyms:
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
(2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraen-1-ol
(2e,4e,6e,8e)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraen-1-ol
(all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
.alpha.lin
.alpha.sterol
.beta.-Retinol
11103-57-4
13123-33-6
1341-18-0
1406-67-3
17104-91-5
1rbp
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclchexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonate-traen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)-2,4,6,8-nonatetraen-1-ol
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer
4-06-00-04133 (Beilstein Handbook Reference)
53637-36-8
5979-23-7
68-26-8
95144_FLUKA
95144_SIGMA
95146_FLUKA
95146_SIGMA
A-Mulsal
A-Sol
A-Vi-Pel
A-Vitan
AC-11701
AC1L9HU3
AC1Q7BU9
ACON
ALL-TRANS RETINOL (SEE ALSO RETINOID PROJECT 1)
AR-1L3057
ATAV
Afaxin
Agiolan
Agoncal
Alcohol 9,13-dimethyl-7-(1,1,5-trimethyl-6-cyclohexen-5-yl)-7,9,11,13-nonatetraen-15-ol
Alcovit A
All Trans Retinol
All-trans retinol
All-trans-Retinol
Alphalin
Alphasterol
Anatola
Anatola A
Anti-infective vitamin
Antixerophthalmic vitamin
Antixerophthalmisches Vitamin
Aoral
Apexol
Apostavit
Aquasol A
Aquasol A Parenteral
Aquasynth
Atars
Avibon
Avita
Avitol
Axerol
Axerophthol
Axerophtholum
BIDD:PXR0102
BRN 0403040
Bentavit A
Biosterol
C00473
C17276
C20H30O
CCRIS 5444
CHEBI:17336
CHEMBL986
CID445354
Chocola A
Chocola a
Cylasphere
D014801
D06543
DB00162
Del-VI-A
Disatabs Tabs
Dofsol
Dohyfral A
EINECS 200-683-7
EINECS 234-328-2
Epiteliol
HMS1921B04
HMS2092L13
HMS501I08
HSDB 815
Hi-A-Vita
Homagenets Aoral
Homagenets aorl
Hydrovit A
IDI1_000486
LMPR01090001
LPK
LS-1578
Lard Factor
M.V.C. 9+3
M.V.I.-12
 
MLS001066379
MLS001074751
MolPort-001-785-962
Mvc Plus
Myvpack
NCGC00091784-01
NCGC00091784-02
NCGC00091784-03
NCGC00091784-04
NCGC00091784-05
NCGC00091784-06
NSC 122759
NSC122759
Nio-A-Let
Oleovitamin A
Ophthalamin
Plivit A
Prepalin
R7632_SIGMA
Retin-11,12-t2-ol (9CI)
Retinol
Retinol [INN:BAN]
Retinol solution
Retinol, all-trans- (8CI)
Retinol-(cellular-retinol-binding-protein)
Retinolo
Retinolo [DCIT]
Retinolum
Retinolum [INN-Latin]
Retrovitamin A
Ro-a-vit
Rovimix A 500
SDCCGMLS-0066724.P001
SMP2_000102
SMR000112036
SPECTRUM1501203
ST057232
Sehkraft A
Solu-A
Spectrum5_000993
Spectrum5_001997
Super A
Testavol
Testavol S
Thalasphere
UNII-81G40H8B0T
UNII-G2SH0XKK91
Vaflol
Vafol
Veroftal
Vi-.alpha.
Vi-Alpha
Vi-Dom-A
Vi-a
Vio-A
Vitamin A
Vitamin A (Feed)
Vitamin A (USP)
Vitamin A alcohol
Vitamin A alcohol (VAN)
Vitamin A cryst
Vitamin A palmitate
Vitamin A1
Vitamin A1 alcohol
Vitamin A1 alcohol, all trans
Vitamin a
Vitamin- A
Vitamin- A alcohol
Vitamin- A alcohol solution
Vitamin- A1
Vitamin-?A
Vitamin-?A alcohol
Vitamin-?A alcohol solution
Vitamin-?A1
Vitamine A
Vitaminum A
Vitavel A
Vitavel-A
Vitpex
Vogan
Vogan-Neu
Vogan-nu
WLN: L6UTJ A1 B1U1Y1&U2U1Y1&U2Q C1 C1
Wachstumsvitamin
ZINC03831417
Zinosan N
[11,12-3H]-Retinol
alin
all-trans-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol
all-trans-Retinol
all-trans-Retinyl alcohol
all-trans-Vitamin A
all-trans-Vitamin A alcohol
all-trans-Vitamin A1
all-trans-retinol
all-trans-retinyl alcohol
all-trans-vitamin A alcohol
b-Retinol
beta-Retinol
retinol
tROL
trans-Retinol
trans-Retinol acid (Vitamin A)
trans-Vitamin A alcohol
trans-retinol
25Contraceptives, Oral, CombinedPhase 3548
26Polyestradiol phosphatePhase 31057
27MineralocorticoidsPhase 3294
28Estradiol 3-benzoatePhase 31057
29Estradiol valeratePhase 31057979-32-8
30Vitamin B ComplexPhase 3, Phase 12775
31Calcium, DietaryPhase 33529
32Estradiol 17 beta-cypionatePhase 31083
33Drospirenone and ethinyl estradiol combinationPhase 375
34Vitamin B 12Phase 3224
35vitamin dPhase 31463
36
SeleniumPhase 31617782-49-2
Synonyms:
Selanediide
Selenide
 
Selenide(2-)
Selenium
Selenium ion (Se2+)
37Retinol palmitatePhase 3386
38Nicotinic AcidsPhase 3340
39TocopherolsPhase 3355
40
CopperPhase 31437440-50-827099
Synonyms:
 
Copper
Cu
41
IodinePhase 34597553-56-2807
Synonyms:
I2
Iode
Iodine-molecule
 
Iodio
Iodum
Jod
Jood
Tincture iodine
42TocotrienolsPhase 3352
43Vitamin B 6Phase 3158
44cadexomer iodinePhase 3425
45Vitamin B12NutraceuticalPhase 3217
46
CobalaminNutraceuticalPhase 321713408-78-16438156
Synonyms:
5,6-Dimethyl-1-a-D-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-a-D-ribofuranosylbenzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
5,6-Dimethyl-1-alpha-delta-ribofuranosylbenzimidazole
Cob(III)alamin
Cobalamin (III)
Cobalamine
 
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester
Cobinamide ion(1+) dihydrogen phosphate (ester) inner salt 3'-ester with 5,6-dimethyl-1-alpha-delta-ribofuranosyl-1H-benzimidazole
Hydroxomin
Rubivite
Rubratope-57
Rubratope-60
Ruvite
Vitamin B12
47Vitamin B9NutraceuticalPhase 3, Phase 12851
48FolateNutraceuticalPhase 3, Phase 12851
49
MethylcobalaminNutraceuticalPhase 321713422-55-4
Synonyms:
Algobaz
Co-Methylcobalamin
Hitocobamin M
MeCbl
Mecobalamin
Methycobal
 
Methyl cobalamine
Methyl vitamin B12
Methyl-5,6-dimethylbenzimidazolylcobalamin
Methyl-B12
Methylcob(III)alamin
Methylcobalamin
Methylcobaz
50Folinic AcidNutraceuticalPhase 3, Phase 12498

Interventional clinical trials:

(show top 50)    (show all 90)
idNameStatusNCT IDPhase
1Brain Function and White Matter Changes in Congenital, Acute and Chronic Spinal Cord LesionsCompletedNCT01208584Phase 4
2Safety and Efficacy Study of Transdermal Oxybutynin to Treat Overactive Bladder With a Neurological ConditionCompletedNCT00224016Phase 4
3Post-Operative Colonization Rates of Femoral Nerve Catheters Treated With Chlorhexidine-Impregnated PatchCompletedNCT01411891Phase 4
4Effect of Botulinum Toxin in Neurogenic Bladders in Children With MyelomeningoceleActive, not recruitingNCT00175123Phase 4
5Efficacy and Safety Study for an Oral Contraceptive Containing FolateCompletedNCT00468481Phase 3
6Study of Treatment With the Combination of Drospirenone Plus Ethinyl Estradiol Plus Levomefolate Calcium in Mexican Women Seeking ContraceptionCompletedNCT01902264Phase 3
7Duragen Versus Duraguard in Chiari SurgeryCompletedNCT00741858Phase 3
8Botox Versus Oxybutynin as First Line Treatment for the Poorly Compliant Pediatric Neurogenic BladderCompletedNCT01716624Phase 3
9A Clinical Study to Investigate How Solifenacin Fluid is Taken up, How Long it Stays in the Body and How Effective and Safe it is in Treating Children Aged From 6 Months to Less Than 5 Years With Symptoms of Neurogenic Detrusor Overactivity (NDO)CompletedNCT01981954Phase 3
10Clinical Trial of a Serious Game for Individuals With SCI/DRecruitingNCT02341950Phase 3
11Folic Acid Dosage and Malformations ReductionActive, not recruitingNCT01244347Phase 3
12Impact of Pre-pregnancy Micronutrient Supplementation on Maternal and Child OutcomesActive, not recruitingNCT01665378Phase 3
13A Study to Assess the Long Term Effect, Safety and Metabolism of a Solifenacin Liquid Suspension in Patients 5 to 18 Years of Age With Neurogenic Detrusor OveractivityActive, not recruitingNCT01565694Phase 3
14A Study to Evaluate Folate Levels in Women Taking Oral ContraceptivesWithdrawnNCT00301587Phase 3
15Lumbar to Sacral Ventral Nerve Re-RoutingCompletedNCT00378664Phase 2
16Coping Skills Training (CST) for Children With Chronic Health ConditionsCompletedNCT00359775Phase 2
17Prevention of Urinary Tract Infection (UTI) in Persons With Spinal Cord Injury (SCI)CompletedNCT00309114Phase 2
18Post T-plant Infusion of Allogeneic Cytokine Induced Killer Cells as Consolidative Therapy in Myelodysplastic Syndromes/Myeloproliferative DisordersRecruitingNCT01392989Phase 2
19Effect of Acetazolamide & Position in CSF Leakage and Collection and Wound DehiscenceRecruitingNCT01867268Phase 2
20Efficacy of Acetaminophen in Posterior Fossa SurgeryRecruitingNCT02532322Phase 2
21Augmentation Cystoplasty Using an Autologous Neo-BladderTerminatedNCT00419120Phase 2
22Probiotics in Girls With Spina BifidaWithdrawnNCT00767988Phase 2
23Prevention of Neural Tube Defects by Inositol in Conjunction With Folic Acid (PONTI Study)CompletedNCT00452829Phase 1
24Fetoscopic Meningomyelocele Repair StudyRecruitingNCT02230072Phase 1
25Mobile Health Self-Management and Support System for Chronic and Complex Health ConditionsRecruitingNCT02592291Phase 1
26Bacteriuria Eradication Through ProbioticsEnrolling by invitationNCT00717600Phase 1
27Does Mid-Gestation Placental Function Assessment Reduce Psychological Distress in Women With High-Risk Pregnancies?Not yet recruitingNCT00546026Phase 1
28Genetic Analysis of Neural Tube and Orofacial Cleft Defects in the Irish PopulationCompletedNCT00341068
29Influence of "Espresso" on Adsorption of Myo-inositolCompletedNCT01244399
30Management of Myelomeningocele Study (MOMS)CompletedNCT00060606
31Folate Metabolism in Normal Weight and Obese Women of Child-bearing AgeCompletedNCT01743196
32Efficacy of Weekly Versus Daily Folic Acid SupplementationCompletedNCT00394862
33Blood Folate and Homocysteine Levels Following Administration of Folic Acid According to Different Daily Dosing Schedules:a Simulation of Food FortificationCompletedNCT00207558
34Micronutrient-supplemented Milk Study in Women of Childbearing AgeCompletedNCT01712165
35Follow-up Study of Late Effects of Periconceptional Folic Acid in Mothers and Offspring in the Community Intervention Program Population: The Chinese Children and Families StudyCompletedNCT01365975
36Influence of Genetics on Vitamin Metabolism in Pregnant WomenCompletedNCT00340366
37Birth Defects Associated With Exposure to Lamotrigine in Pregnancy (EUROCAT)CompletedNCT01055327
38Effects of Maternal Folate and Folic Acid Supplementation on DNA Methylation in the Newborn InfantCompletedNCT02244684
39Dosage Effects of Folic Acid on Blood Folates of Honduran WomenCompletedNCT00207532
40Cognitive Rehabilitation in Patients With Spina BifidaCompletedNCT01302314
41Comparing Urinary Tract Infections in Children With Spina Bifida Using Two Types of Catheters for CatheterizationCompletedNCT01263392
42Virtual Reality Based Testing of Power Wheelchair Driving SkillsCompletedNCT00951509
43A Randomized Exercise Trial for Wheelchair UsersCompletedNCT00866112
44Metformin in Children With Motor DeficitCompletedNCT00720161
45Prevention of Post Operative Bone Loss in ChildrenCompletedNCT00655681
46Hemangioma Associated With High Rates of MorbidityCompletedNCT00394888
47Feasibility of the Portable YouGrabber SystemCompletedNCT02368223
48Establishing the Physiology of SyringomyeliaCompletedNCT00001327
49Genetics of Neural Tube DefectsRecruitingNCT01253746
50Genetics of Spina Bifida and AnencephalyRecruitingNCT00636233

Search NIH Clinical Center for Neural Tube Defects

Genetic Tests for Neural Tube Defects

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Genetic tests related to Neural Tube Defects:

id Genetic test Affiliating Genes
1 Neural Tube Defect22 24

Anatomical Context for Neural Tube Defects

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MalaCards organs/tissues related to Neural Tube Defects:

33
Brain, Spinal cord, Bone, Skin, Heart, Testes, Testis

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Neural Tube Defects:
id TissueAnatomical CompartmentCell Relevance
1 Neural TubeNeural Tube  Affected by disease

Animal Models for Neural Tube Defects or affiliated genes

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MGI Mouse Phenotypes related to Neural Tube Defects:

38 (show all 18)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000118610.6CCL2, FUZ, PAX3, PDGFRA, ZIC2
2MP:000537710.3CELSR1, FUZ, FZD6, PAX3, SCRIB, VANGL1
3MP:000538210.2CBS, CCL2, CELSR1, FUZ, PAX3, PDGFRA
4MP:000538110.1CCL2, DACT1, FUZ, PAX3, PDGFRA, SCRIB
5MP:000536710.1CBS, DACT1, PAX3, PDGFRA, SCRIB, SLC19A1
6MP:000539010.0CCL2, CELSR1, DACT1, FUZ, MTHFR, PAX3
7MP:000538810.0CBS, CELSR1, FUZ, PAX3, PDGFRA, SCRIB
8MP:000539110.0CBS, CCL2, CELSR1, FUZ, FZD6, MTHFR
9MP:00053859.9CBS, CCL2, DACT1, FUZ, MTHFD1, PAX3
10MP:00107719.7CBS, CCL2, CELSR1, FZD6, MTHFR, PAX3
11MP:00053719.7CBS, CELSR1, DACT1, FUZ, FZD6, MTHFD1
12MP:00053869.6AFP, CBS, CCL2, CELSR1, PAX3, PDGFRA
13MP:00053809.6CBS, CELSR1, DACT1, FUZ, FZD6, MTHFD1
14MP:00053899.4AFP, CBS, CCL2, DACT1, FZD6, MTHFR
15MP:00053789.4CBS, CCL2, CELSR1, DACT1, MTHFD1, MTHFR
16MP:00036319.1CCL2, CELSR1, DACT1, FUZ, FZD6, MTHFD1
17MP:00107689.1AFP, CBS, CCL2, CELSR1, DACT1, FUZ
18MP:00053769.0AFP, CBS, CCL2, CELSR1, FUZ, MTHFD1

Publications for Neural Tube Defects

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Articles related to Neural Tube Defects:

(show top 50)    (show all 764)
idTitleAuthorsYear
1
Prevalence of congenital defects including selected neural tube defects in Nepal: results from a health survey. (26391586)
2015
2
Pre-conception Folic Acid and Multivitamin Supplementation for the Primary and Secondary Prevention of Neural Tube Defects and Other Folic Acid-Sensitive Congenital Anomalies. (26334606)
2015
3
Abnormal epigenetic regulation of the gene expression levels of Wnt2b and Wnt7b: Implications for neural tube defects. (26548512)
2015
4
The levels of vitamA+n B12, folate, and homocysteine in mothers and their babies with neural tube defects. (26479326)
2015
5
DNA methylation aberrations rather than polymorphisms of FZD3 gene increase the risk of spina bifida in a high-risk region for neural tube defects. (25131656)
2014
6
Association between VANGL1 Gene Polymorphisms and Neural Tube Defects. (24407469)
2014
7
Neural tube defects, folic acid and methylation. (24048206)
2013
8
Novel mutations in Lrp6 orthologs in mouse and human neural tube defects affect a highly dosage-sensitive Wnt non-canonical planar cell polarity pathway. (24203697)
2013
9
Genetic analysis of disheveled 2 and disheveled 3 in human neural tube defects. (22892949)
2013
10
Is LMNB1 a susceptibility gene for neural tube defects in humans? (23733478)
2013
11
The amniotic fluid as a source of neural stem cells in the setting of experimental neural tube defects. (22957979)
2013
12
Knowledge and periconceptional use of folic acid for the prevention of neural tube defects in ethnic communities in the United Kingdom: systematic review and meta-analysis. (23873812)
2013
13
A GCH1 haplotype and risk of neural tube defects in the National Birth Defects Prevention Study. (23059057)
2012
14
Multiple neural tube defects in a child: A rare developmental anomaly. (23372964)
2012
15
Standardized Procedural Practices of the Ontario Prenatal Screening Program for aneuploidies and open neural tube defects. (22732525)
2012
16
Serum ischemia modified albumin levels in pregnancies with neural tube defects. (22324268)
2012
17
Association of selected persistent organic pollutants in the placenta with the risk of neural tube defects. (21768370)
2011
18
Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans. (21840926)
2011
19
Policy statement on folic acid and neural tube defects. (21552133)
2011
20
Importance of including all pregnancy outcomes to reduce bias in epidemiologic studies of neural tube defects--Texas, 1999 to 2005. (21290567)
2011
21
The emerging role of epigenetic mechanisms in the etiology of neural tube defects. (21613818)
2011
22
Gender-dependent differences in the incidence of ochratoxin A-induced neural tube defects in the Pdn/Pdn mouse. (20201966)
2010
23
Neural tube defects in Australia: trends in encephaloceles and other neural tube defects before and after promotion of folic acid supplementation and voluntary food fortification. (19180646)
2009
24
Recent perspectives on the genetic background of neural tube defects with special regard to iniencephaly. (19379086)
2009
25
Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview. (19180567)
2009
26
Thrombophilia-associated gene mutations in women with pregnancies complicated by fetal neural tube defects. (18068170)
2008
27
Syndromes, disorders and maternal risk factors associated with neural tube defects (IV). (18603497)
2008
28
The hair collar sign as a marker for neural tube defects. (17461809)
2007
29
Health literacy and patient understanding of screening tests for aneuploidy and neural tube defects. (17345585)
2007
30
Vitamin B12 and the risk of neural tube defects in a folic-acid-fortified population. (17474166)
2007
31
Reduced folate carrier gene is a risk factor for neural tube defects in a Chinese population. (15799025)
2005
32
Maternal diabetes and neural tube defects: prenatal diagnosis of lumbosacral myelomeningocele, ventriculomegaly, Arnold-Chiari malformation and foot deformities in a pregnancy with poor maternal metabolic control, and review of the literature. (16259331)
2005
33
Haplotype-dependent binding of nuclear proteins to the promoter of the neural tube defects-associated platelet-derived growth factor alpha-receptor gene. (16126374)
2005
34
Gene-gene interaction in folate-related genes and risk of neural tube defects in a UK population. (15060097)
2004
35
Independent mutations in mouse Vangl2 that cause neural tube defects in looptail mice impair interaction with members of the Dishevelled family. (15456783)
2004
36
Promoter haplotype combinations for the human PDGFRA gene are associated with risk of neural tube defects. (14741194)
2004
37
Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects. (12107818)
2002
38
Human T and risk for neural tube defects. (11897834)
2002
39
A novel mutation in the gene encoding noggin is not causative in human neural tube defects. (12420790)
2002
40
Rudimentary meningocele: remnant of a neural tube defect? (11176660)
2001
41
Neural tube defects in the Asir Region of Saudi Arabia. (17264584)
2001
42
Multicentric study of efficacy of periconceptional folic acid containing vitamin supplementation in prevention of open neural tube defects from India. (11247198)
2000
43
Heterotaxy-neural tube defect and holoprosencephaly occuring independently in two sib fetuses. (10340655)
1999
44
Molecular genetic analysis of human folate receptors in neural tube defects. (10234517)
1999
45
Methionine synthase: high-resolution mapping of the human gene and evaluation as a candidate locus for neural tube defects. (10444343)
1999
46
Neurofibromin deficiency in mice causes exencephaly and is a modifier for Splotch neural tube defects. (10419687)
1999
47
Physical and transcriptional map of a 3-Mb region of mouse chromosome 1 containing the gene for the neural tube defect mutant loop-tail (Lp). (10051400)
1999
48
Association of the 677C-->T mutation on the methylenetetrahydrofolate reductase gene in Turkish patients with neural tube defects. (10190266)
1999
49
Identical twins with Weissenbacher-ZweymA1ller syndrome and neural tube defect. (8456835)
1993
50
Amniotic fluid cholinesterase of valproate-induced exencephaly in the mouse: an animal model for prenatal diagnosis of neural tube defects. (3142446)
1988

Variations for Neural Tube Defects

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UniProtKB/Swiss-Prot genetic disease variations for Neural Tube Defects:

67 (show all 12)
id Symbol AA change Variation ID SNP ID
1CELSR1p.Ala773ValVAR_067213rs12170597
2CELSR1p.Arg2438GlnVAR_067215rs199688538
3CELSR1p.Ser2964LeuVAR_067217rs6008777
4CELSR1p.Pro2983AlaVAR_067218rs61741871
5DACT1p.Asn356LysVAR_068429
6SCRIBp.Pro454SerVAR_067219
7SCRIBp.Arg1535GlnVAR_067220
8VANGL1p.Arg274GlnVAR_035210
9VANGL1p.Met328ThrVAR_035211
10VANGL2p.Ser84PheVAR_067221
11VANGL2p.Arg353CysVAR_067222
12VANGL2p.Phe437SerVAR_067223

Clinvar genetic disease variations for Neural Tube Defects:

5
id Gene Variation Type Significance SNP ID Assembly Location
1CCL2NG_012123.1: g.2493A> Gsingle nucleotide variantPathogenic, risk factorrs1024611GRCh37Chr 17, 32579788: 32579788

Expression for genes affiliated with Neural Tube Defects

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LifeMap Discovery
Genes differentially expressed in tissues of Neural Tube Defects patients vs. healthy controls: 32 (show all 154)
id Gene Description Tissue Up/Dn Fold Change (log2) P value
1DDX3YDEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linkedAmnion-8.640.000
2RPS4Y1ribosomal protein S4, Y-linked 1Amnion-7.410.000
3EIF1AYeukaryotic translation initiation factor 1A, Y-linkedAmnion-7.250.000
4GRIA2glutamate receptor, ionotropic, AMPA 2Amnion+5.600.000
5CNTN1contactin 1Amnion+4.720.005
6THBS1thrombospondin 1Amnion-4.680.000
7FABP7fatty acid binding protein 7, brainAmnion+4.600.003
8PMP2peripheral myelin protein 2Amnion+4.490.024
9CADM2cell adhesion molecule 2Amnion+4.330.010
10GPM6Aglycoprotein M6AAmnion+4.280.006
11SCG3secretogranin IIIAmnion+4.200.002
12NLGN4Xneuroligin 4, X-linkedAmnion+4.190.012
13PPP1R3Fprotein phosphatase 1, regulatory subunit 3FAmnion+4.180.000
14SLC1A6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6Amnion-4.170.010
15POU2F2POU class 2 homeobox 2Amnion+4.170.000
16OVOL1ovo-like zinc finger 1Amnion-4.150.000
17NRTNneurturinAmnion-4.130.016
18KRT24keratin 24, type IAmnion-4.120.000
19GPM6Bglycoprotein M6BAmnion+4.010.039
20LHFPL3lipoma HMGIC fusion partner-like 3Amnion+4.010.012
21TXLNGYtaxilin gamma pseudogene, Y-linkedAmnion-3.960.003
22NKX2-2NK2 homeobox 2Amnion+3.950.009
23NKX2-3NK2 homeobox 3Amnion-3.920.000
24WSCD1WSC domain containing 1Amnion+3.900.003
25ADGRL3adhesion G protein-coupled receptor L3Amnion+3.830.014
26MXD1MAX dimerization protein 1Amnion-3.830.015
27AASSaminoadipate-semialdehyde synthaseAmnion+3.790.001
28IZUMO1izumo sperm-egg fusion 1Amnion+3.790.001
29SH3GL2SH3-domain GRB2-like 2Amnion+3.790.014
30AP1S3adaptor-related protein complex 1, sigma 3 subunitAmnion-3.780.000
31ETNPPLethanolamine-phosphate phospho-lyaseAmnion-3.730.005
32ORF1uncharacterized protein, clone pT-Adv JuaX22Amnion+3.710.007
33ZNF428zinc finger protein 428Amnion+3.700.002
34KANK4KN motif and ankyrin repeat domains 4Amnion-3.690.002
35KCNC2potassium channel, voltage gated Shaw related subfamily C, member 2Amnion-3.670.031
36ZIC2Zic family member 2Amnion+3.670.043
37ZFYzinc finger protein, Y-linkedAmnion-3.670.005
38SLC7A2solute carrier family 7 (cationic amino acid transporter, y+ system), member 2Amnion-3.660.023
39CD36CD36 molecule (thrombospondin receptor)Amnion+3.650.014
40ADSSL1adenylosuccinate synthase like 1Amnion+3.650.025
41CECR9cat eye syndrome chromosome region, candidate 9 (non-protein coding)Amnion+3.640.004
42NXPH1neurexophilin 1Amnion+3.640.041
43MFAP5microfibrillar associated protein 5Amnion-3.610.004
44AUTS2autism susceptibility candidate 2Amnion+3.590.012
45KCTD7potassium channel tetramerization domain containing 7Amnion-3.590.000
46ASCL1achaete-scute family bHLH transcription factor 1Amnion+3.590.014
47MUC15mucin 15, cell surface associatedAmnion-3.530.043
48MUSTN1musculoskeletal, embryonic nuclear protein 1Amnion+3.520.007
49MYT1myelin transcription factor 1Amnion+3.520.002
50DNAJC24DnaJ (Hsp40) homolog, subfamily C, member 24Amnion+3.510.013
51C2orf80chromosome 2 open reading frame 80Amnion+3.500.012
52CRMP1collapsin response mediator protein 1Amnion+3.490.004
53TRIM9tripartite motif containing 9Amnion+3.480.017
54GPX8glutathione peroxidase 8 (putative)Amnion-3.470.003
55AKNAAT-hook transcription factorAmnion+3.450.005
56PTENphosphatase and tensin homologAmnion+3.450.019
57CACUL1CDK2-associated, cullin domain 1Amnion+3.440.001
58CACNA1Dcalcium channel, voltage-dependent, L type, alpha 1D subunitAmnion+3.430.006
59ARHGEF28Rho guanine nucleotide exchange factor (GEF) 28Amnion-3.400.000
60PDZRN3PDZ domain containing ring finger 3Amnion-3.400.026
61ZFYVE16zinc finger, FYVE domain containing 16Amnion+3.380.032
62LRRTM2leucine rich repeat transmembrane neuronal 2Amnion+3.370.014
63FAM161Afamily with sequence similarity 161, member AAmnion+3.360.002
64CAB39Lcalcium binding protein 39-likeAmnion-3.360.023
65MYSM1Myb-like, SWIRM and MPN domains 1Amnion-3.350.007
66EDN1endothelin 1Amnion-3.340.001
67LRRIQ1leucine-rich repeats and IQ motif containing 1Amnion+3.340.008
68PCDHB3protocadherin beta 3Amnion+3.340.003
69MSH3mutS homolog 3Amnion+3.330.026
70CHD9chromodomain helicase DNA binding protein 9Amnion+3.330.018
71KRT40keratin 40, type IAmnion-3.330.001
72AOX1aldehyde oxidase 1Amnion-3.320.007
73BAHCC1BAH domain and coiled-coil containing 1Amnion+3.320.001
74LOC645321uncharacterized LOC645321Amnion+3.300.000
75HUS1BHUS1 checkpoint clamp component BAmnion+3.300.004
76GFAPglial fibrillary acidic proteinAmnion+3.290.022
77DHFRdihydrofolate reductaseAmnion+3.290.027
78STMN2stathmin 2Amnion+3.290.047
79OLIG1oligodendrocyte transcription factor 1Amnion+3.280.050
80LINC00597long intergenic non-protein coding RNA 597Amnion+3.280.041
81RIC1RIC1 homolog, RAB6A GEF complex partner 1Amnion-3.280.001
82SERPINB13serpin peptidase inhibitor, clade B (ovalbumin), member 13Amnion-3.270.001
83DNAH9dynein, axonemal, heavy chain 9Amnion+3.260.006
84KCNQ4potassium channel, voltage gated KQT-like subfamily Q, member 4Amnion+3.260.012
85GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetaseAmnion+3.260.011
86EPHX1epoxide hydrolase 1, microsomal (xenobiotic)Amnion+3.250.000
87GCC1GRIP and coiled-coil domain containing 1Amnion+3.240.012
88APBA2amyloid beta (A4) precursor protein-binding, family A, member 2Amnion+3.240.006
89GJB6gap junction protein, beta 6, 30kDaAmnion-3.230.021
90OR5I1olfactory receptor, family 5, subfamily I, member 1Amnion+3.220.002
91PLEKHB2pleckstrin homology domain containing, family B (evectins) member 2Amnion+3.220.002
92ITSN1intersectin 1 (SH3 domain protein)Amnion+3.220.009
93CD99P1CD99 molecule pseudogene 1Amnion-3.220.001
94ZNF556zinc finger protein 556Amnion-3.220.024
95LRTM2leucine-rich repeats and transmembrane domains 2Amnion+3.210.015
96IGFBP3insulin-like growth factor binding protein 3Amnion-3.210.012
97HOXD9homeobox D9Amnion+3.200.001
98NFASCneurofascinAmnion+3.200.029
99OLIG2oligodendrocyte lineage transcription factor 2Amnion+3.190.007
100LRRC16Bleucine rich repeat containing 16BAmnion+3.190.020
101KDM5Dlysine (K)-specific demethylase 5DAmnion-3.190.003
102CRATcarnitine O-acetyltransferaseAmnion+3.180.001
103UVSSAUV-stimulated scaffold protein AAmnion+3.180.006
104SOX1SRY (sex determining region Y)-box 1Amnion+3.180.013
105ZNF555zinc finger protein 555Amnion-3.170.034
106RGS9BPregulator of G protein signaling 9 binding proteinAmnion-3.170.001
107ACTR3CARP3 actin-related protein 3 homolog C (yeast)Amnion-3.170.000
108ERC2ELKS/RAB6-interacting/CAST family member 2Amnion+3.170.018
109GPRC5BG protein-coupled receptor, class C, group 5, member BAmnion+3.170.022
110NTRK2neurotrophic tyrosine kinase, receptor, type 2Amnion+3.160.018
111ZNF318zinc finger protein 318Amnion+3.160.003
112PPP1R1Aprotein phosphatase 1, regulatory (inhibitor) subunit 1AAmnion+3.160.012
113TMEM37transmembrane protein 37Amnion+3.150.034
114GRIK2glutamate receptor, ionotropic, kainate 2Amnion+3.150.010
115EMX2empty spiracles homeobox 2Amnion-3.150.009
116SDSserine dehydrataseAmnion+3.150.002
117PDGFCplatelet derived growth factor CAmnion+3.150.011
118GRIN2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2DAmnion+3.150.001
119FAM120AOSfamily with sequence similarity 120A opposite strandAmnion+3.140.001
120C14orf180chromosome 14 open reading frame 180Amnion+3.130.031
121CDC45cell division cycle 45Amnion+3.120.023
122DUSP26dual specificity phosphatase 26 (putative)Amnion+3.120.037
123GPR39G protein-coupled receptor 39Amnion-3.110.043
124ARCactivity-regulated cytoskeleton-associated proteinAmnion+3.110.031
125SOS2son of sevenless homolog 2 (Drosophila)Amnion-3.110.003
126SYT7synaptotagmin VIIAmnion+3.100.049
127ABCD2ATP-binding cassette, sub-family D (ALD), member 2Amnion+3.100.040
128CLCA4chloride channel accessory 4Amnion-3.100.023
129TTBK2tau tubulin kinase 2Amnion+3.090.045
130TMEM116transmembrane protein 116Amnion+3.090.011
131SYNGR3synaptogyrin 3Amnion-3.090.028
132ZNRF1zinc and ring finger 1, E3 ubiquitin protein ligaseAmnion+3.090.001
133TSPAN16tetraspanin 16Amnion+3.080.038
134LOC100128002uncharacterized LOC100128002Amnion+3.080.001
135ZIC3Zic family member 3Amnion+3.070.014
136SOX8SRY (sex determining region Y)-box 8Amnion+3.070.004
137CTNND2catenin (cadherin-associated protein), delta 2Amnion+3.060.006
138JSRP1junctional sarcoplasmic reticulum protein 1Amnion+3.060.001
139TTTY14testis-specific transcript, Y-linked 14 (non-protein coding)Amnion-3.060.007
140HSD17B6hydroxysteroid (17-beta) dehydrogenase 6Amnion+3.050.000
141TNFSF12tumor necrosis factor (ligand) superfamily, member 12Amnion+3.050.018
142PTGER3prostaglandin E receptor 3 (subtype EP3)Amnion+3.040.016
143RALGAPA1Ral GTPase activating protein, alpha subunit 1 (catalytic)Amnion+3.040.010
144TNNI2troponin I type 2 (skeletal, fast)Amnion+3.040.005
145RNF168ring finger protein 168, E3 ubiquitin protein ligaseAmnion+3.040.036
146CASRcalcium-sensing receptorAmnion+3.040.008
147LINC00304long intergenic non-protein coding RNA 304Amnion+3.040.001
148NCLNnicalinAmnion+3.030.013
149ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)Amnion+3.030.005
150SGMS2sphingomyelin synthase 2Amnion-3.020.006
151KRTDAPkeratinocyte differentiation-associated proteinAmnion-3.010.039
152CCL13chemokine (C-C motif) ligand 13Amnion+3.010.000
153MRPL39mitochondrial ribosomal protein L39Amnion+3.010.035
154CAMK2Dcalcium/calmodulin-dependent protein kinase II deltaAmnion+3.000.019

Search GEO for disease gene expression data for Neural Tube Defects.

Pathways for genes affiliated with Neural Tube Defects

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Pathways related to Neural Tube Defects according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
10.3MTR, MTRR
210.3CBS, MTHFR
310.3CBS, MTR
4
Show member pathways
10.2CBS, MTR, MTRR
5
Show member pathways
10.1CBS, CCL2, MTHFR, MTR
6
Show member pathways
10.0MTHFD1, MTHFR, MTR, MTRR, SLC19A1
7
Show member pathways
10.0CBS, MTHFD1, MTHFR, MTR, MTRR
810.0AFP, FZD6, PAX3, SCRIB, VANGL1

GO Terms for genes affiliated with Neural Tube Defects

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Biological processes related to Neural Tube Defects according to GeneCards Suite gene sharing:

(show all 28)
idNameGO IDScoreTop Affiliating Genes
1apical protein localizationGO:004517610.8CELSR1, VANGL2
2establishment of body hair planar orientationGO:004810510.8CELSR1, VANGL2
3orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048810.8CELSR1, VANGL2
4planar dichotomous subdivision of terminal units involved in lung branching morphogenesisGO:006048910.8CELSR1, VANGL2
5lateral sprouting involved in lung morphogenesisGO:006049010.8CELSR1, VANGL2
6planar cell polarity pathway involved in neural tube closureGO:009017910.8CELSR1, VANGL2
7methionine metabolic processGO:000655510.8MTHFD1, MTHFR, MTRR
8tetrahydrofolate interconversionGO:003599910.8MTHFD1, MTHFR
9non-canonical Wnt signaling pathwayGO:003556710.8FZD6, VANGL2
10astrocyte cell migrationGO:004361510.7CCL2, SCRIB
11developmental pigmentationGO:004806610.7PAX3, ZIC2
12cobalamin metabolic processGO:000923510.7MTR, MTRR
13homocysteine catabolic processGO:004341810.7CBS, MTRR
14post-anal tail morphogenesisGO:003634210.7T, VANGL2
15establishment of planar polarityGO:000173610.6CELSR1, FUZ, FZD6, VANGL2
16transsulfurationGO:001934610.6CBS, MTHFD1
17Wnt signaling pathway, planar cell polarity pathwayGO:006007110.6FZD6, VANGL2
18homocysteine metabolic processGO:005066710.6CBS, MTHFR
19anterior/posterior pattern specificationGO:000995210.6CELSR1, T, VANGL2
20methionine biosynthetic processGO:000908610.6MTHFD1, MTHFR, MTR, MTRR
21sulfur amino acid metabolic processGO:000009610.5CBS, MTR, MTRR
22wound healingGO:004206010.1CELSR1, PDGFRA, SCRIB, VANGL2
23vitamin metabolic processGO:000676610.1MTHFD1, MTHFR, MTR, MTRR, SLC19A1
24folic acid metabolic processGO:004665510.1MTHFD1, MTHFR, MTRR, SLC19A1
25water-soluble vitamin metabolic processGO:000676710.1MTHFD1, MTHFR, MTR, MTRR, SLC19A1
26hair follicle developmentGO:000194210.0CELSR1, FUZ, FZD6, VANGL2
27neural tube closureGO:00018439.9CELSR1, FUZ, FZD6, MTHFD1, PAX3, SCRIB
28inner ear morphogenesisGO:00424729.9CELSR1, FZD6, ZIC1

Molecular functions related to Neural Tube Defects according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1modified amino acid bindingGO:007234110.3CBS, MTHFR

Sources for Neural Tube Defects

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet