MCID: NRL005
MIFTS: 50

Neurilemmoma malady

Rare diseases, Neuronal diseases categories

Aliases & Classifications for Neurilemmoma

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Neurilemmoma, Aliases & Descriptions:

Name: Neurilemmoma 9 11 60
Schwannoma 9 41 43
Plexiform Schwannoma 41 60
Cellular Schwannoma 41 60
Acoustic Neuroma 41 60
Psammomatous Schwannoma 9
Melanotic Neurilemmoma 60
 
Vestibular Schwannoma 41
Melanotic Schwannoma 41
Acoustic Neurilemoma 41
Acoustic Neurinoma 41
Neurilemoma 41
Neurinoma 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Neuronal diseases


External Ids:

Disease Ontology9 DOID:3192
MeSH33 D009442
NCIt38 C3269

Summaries for Neurilemmoma

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NIH Rare Diseases:41 Schwannomas are tumors of the tissue that covers the nerves (nerve sheath). these tumors develop from a type of cell called a schwann cell, which gives these tumors their name. they are usually benign (not cancerous). although schwannomas can arise from any nerve in the body, the most common areas include the nerves of the head and neck and those involved with moving the arms and legs. common symptoms include a slow-growing mass and tinel's sign (an electric-like shock when the affected area is touched). the cause of schwannomas is unknown, but they sometimes occur in people with certain disorders including some types of neurofibromatosis. benign schwannomas are typically treated with surgery. last updated: 3/9/2015

MalaCards based summary: Neurilemmoma, also known as schwannoma, is related to neurofibromatosis, type 2 and spinal cord ependymoma. An important gene associated with Neurilemmoma is MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal), and among its related pathways are Striated Muscle Contraction and Neuroscience. The compounds eosin and toluidine have been mentioned in the context of this disorder. Affiliated tissues include tongue, bone and thyroid, and related mouse phenotypes are respiratory system and vision/eye.

Wikipedia:63 A schwannoma (also known as an \"neurilemoma,\" \"neuroma,\" \"neurolemoma,\" and \"Schwann cell... more...

Related Diseases for Neurilemmoma

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Diseases related to Neurilemmoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 323)
idRelated DiseaseScoreTop Affiliating Genes
1neurofibromatosis, type 231.1NF1, NF2
2spinal cord ependymoma30.9NF2
3malignant peripheral nerve sheath tumor30.7B3GAT1, NF1
4choroid plexus papilloma30.7GFAP
5granular cell tumor30.7VIM, ENO2
6neurofibrosarcoma30.6NF2, NF1
7angiosarcoma30.6VIM, CD34
8perineurioma30.5VIM, CD34
9acoustic neuroma30.5NF1, NF2
10fibroma30.5VIM, CD34
11glomus tumor30.5VIM
12neuroectodermal tumor30.4NF1, ENO2
13tanycytic ependymoma30.4NF2, GFAP
14chondrosarcoma30.3ENO2, VIM
15neurofibroma30.3VIM, NF2, NF1, CD34
16chordoma30.2GFAP, VIM
17rhabdoid tumor30.2VIM, SMARCB1
18hemangioblastoma30.2GFAP, ENO2
19glioblastoma30.2NF1, GFAP, SMARCB1
20ganglioneuroma30.1ENO2, GFAP
21hemangiopericytoma30.1CD34, VIM
22neurofibromatosis30.1NF1, NF2
23leiomyoma30.0VIM, CD34
24multiple endocrine neoplasia30.0NF1, NF2
25hemangioma30.0CD34, NF1
26pleomorphic adenoma30.0VIM, GFAP
27pilocytic astrocytoma29.9NF1, GFAP
28mesothelioma29.9CD34, NF2, VIM
29gastrointestinal stromal tumor29.9VIM, NF2, NF1, ENO2, CD34
30neuroendocrine tumor29.8ENO2, NF1
31rhabdomyosarcoma29.8SMARCB1, VIM, ENO2
32ependymoma29.8GFAP, VIM, NF2, NF1, ENO2
33adenocarcinoma29.7VIM, NF2, ENO2, CD34
34ganglioglioma29.7GFAP, ENO2
35paraganglioma29.7GFAP, NF1, ENO2
36leiomyosarcoma29.6CD34, ENO2, VIM, SMARCB1
37retinoblastoma29.6SMARCB1, GFAP, NF1, ENO2
38melanoma29.3VIM, NF2, NF1, ENO2, CD34
39astrocytoma29.3GFAP, VIM, NF2, NF1, B3GAT1
40sarcoma29.2SMARCB1, VIM, NF2, NF1, B3GAT1, ENO2
41cerebrospinal fluid leak10.7
42headache10.7
43banf acoustic neurinoma10.6
44cervicitis10.6
45meningitis10.5
46metanephric adenoma10.5B3GAT1
47secretory meningioma10.5VIM
48hydrocephalus10.5
49epithelioid sarcoma10.5SMARCB1
50congenital mesoblastic nephroma10.5SMARCB1

Graphical network of the top 20 diseases related to Neurilemmoma:



Diseases related to neurilemmoma

Symptoms for Neurilemmoma

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Drugs & Therapeutics for Neurilemmoma

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Drug clinical trials:

Search ClinicalTrials for Neurilemmoma

Search NIH Clinical Center for Neurilemmoma

Genetic Tests for Neurilemmoma

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Anatomical Context for Neurilemmoma

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MalaCards organs/tissues related to Neurilemmoma:

31
Tongue, Bone, Thyroid, Breast, Lymph node, Kidney, Tonsil, Skin, Cervix, Spinal cord, Heart, Skeletal muscle, Colon, Liver, Lung, Salivary gland, Ovary, Testis, Trachea, Appendix

Animal Models for Neurilemmoma or affiliated genes

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MGI Mouse Phenotypes related to Neurilemmoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.6ENO2, NF1, NF2, VIM
2MP:00053918.3SMARCB1, GFAP, VIM, NF2, NF1
3MP:00020068.1SMARCB1, NF2, NF1, CD34
4MP:00053867.8GFAP, VIM, NF2, NF1, B3GAT1, ENO2
5MP:00036317.4ENO2, B3GAT1, NF1, NF2, VIM, GFAP
6MP:00053877.4SMARCB1, GFAP, VIM, NF2, NF1, CD34
7MP:00053847.2SMARCB1, GFAP, VIM, NF1, ENO2, CD34
8MP:00053767.0SMARCB1, GFAP, VIM, NF2, NF1, CD34

Publications for Neurilemmoma

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Articles related to Neurilemmoma:

(show top 50)    (show all 431)
idTitleAuthorsYear
1
Intraosseous neurilemmoma of the proximal ulna. (25460435)
2014
2
Laparoscopic phrenectomy for a diaphragmatic neurilemmoma. (24250705)
2013
3
Value of ultrasonography in neurilemmoma diagnosis: the role of round shape morphology. (22957323)
2012
4
Giant neurilemmoma of the vagus nerve: a case report and review of literature. (23936960)
2012
5
Wagner-Meissner neurilemmoma of the right cheek. (18486897)
2008
6
Thigh pain due to intraspinal neurilemmoma. (12932385)
2003
7
Cerebral infarction due to carotid occlusion caused by cervical vagal neurilemmoma: report of a case. (11988627)
2002
8
A painful subcutaneous neurilemmoma attached to a peripheral nerve. (9448222)
1998
9
Intraosseous neurilemmoma of the fibula. (9040146)
1997
10
Jugular foramen neurilemmoma mimicking an intra-axial brainstem tumor--a case report. (8843014)
1996
11
Neurilemmoma of the posterior tibial nerve with an uncommon case presentation. (1619219)
1992
12
Neurilemmoma in the maxillary alveolar bone: report of a case. (1873292)
1991
13
A rare endobronchial neurilemmoma (Schwannoma). (2914500)
1989
14
Polypoid neurilemmoma of the trachea: an unusual cause of major airway obstruction. (3250429)
1988
15
A combined neurilemmoma and angioma of the parasellar region. Case report. (3598695)
1987
16
Pathologic quiz case 2. Neurilemmoma (schwannoma). (3675901)
1987
17
Plexiform neurilemmoma: a clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. (3114942)
1987
18
Anterior uveal neurilemmoma--a rare neoplasm simulating malignant melanoma. (3545285)
1987
19
Tapia's syndrome caused by a neurilemmoma of vagus and hypoglossal nerves in the neck. (3799257)
1986
20
Gastric neurilemmoma: case report. (3878467)
1985
21
Spinal subdural hematoma, neurilemmoma, and acute transverse myelopathy. (3975824)
1985
22
Epithelioid neurilemmoma of the trigeminal nerve: an immunohistochemical and ultrastructural study. (3913635)
1985
23
Atypical central neurilemmoma of the mandible. (3856819)
1985
24
Mesenchymal differentiation in trigeminal neurilemmoma. (7116288)
1982
25
Regional Multiplicity of a neurilemmoma. (7061018)
1982
26
Neurilemmoma of the pterygo-maxillary fossa. (7229524)
1981
27
Neurilemmoma of optic nerve. (7216356)
1980
28
Neurilemmoma of the vagus nerve. (7212623)
1980
29
Neurilemmoma of the foot: a case report. (762394)
1979
30
Trigger finger due to neurilemmoma in the carpal tunnel. (738662)
1978
31
Retroperitoneal neurilemmoma. (675931)
1978
32
Tarsal-tunnel syndrome caused by neurilemmoma of the medial plantar nerve. A case report. (833162)
1977
33
Endocystography in cystic neurilemmoma. (876448)
1977
34
Neurilemmoma (schwannoma) of the larynx. (1123570)
1975
35
Calcification within a thoracic neurilemmoma. (4444769)
1974
36
Neurilemmoma of the pharynx. (5021025)
1972
37
Intraparotid facial neurilemmoma. (5443951)
1970
38
Malignant neurilemmoma of parotid gland. (5491649)
1970
39
Pulmonary neurilemmoma. (5476293)
1970
40
Neurilemmoma of the cheek. Report of a case. (5230128)
1967
41
NEURILEMMOMA OF THE FACIAL NERVE. (14119586)
1964
42
Neurilemmoma of the cervical sympathetic chain. (14024784)
1963
43
Palpebral neurilemmoma. (14422917)
1960
44
The neurosurgical aspects of seventh nerve neurilemmoma. (13825709)
1960
45
Neurilemmoma of the diaphragm causing severe hypertrophic pulmonary osteoarthropathy. (13560782)
1958
46
Neurilemmoma of the diaphragm. (13320560)
1956
47
Neurilemmoma of the sigmoid colon, associated with diverticulitis as a cause of obstruction. (14388189)
1955
48
Neurilemmoma (Schwannoma) of the larynx. (13136231)
1953
49
Neurilemmoma of pharynx. (12996927)
1952
50
Neurilemmoma of the pharynx. (20266777)
1947

Variations for Neurilemmoma

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Expression for genes affiliated with Neurilemmoma

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Search GEO for disease gene expression data for Neurilemmoma.

Pathways for genes affiliated with Neurilemmoma

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Pathways related to Neurilemmoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8MYH8, VIM
29.0ENO2, NF2, GFAP
3
Show member pathways
8.7NF1, MYH8, VIM, GFAP

Compounds for genes affiliated with Neurilemmoma

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Compounds related to Neurilemmoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1eosin4310.0VIM, GFAP
2toluidine4310.0ENO2, VIM
3retinaldehyde4310.0VIM, GFAP
4silicone439.9VIM, GFAP
5streptozotocin439.8VIM, GFAP
6homovanillic acid43 2410.8GFAP, ENO2
72-mercaptoethanol439.8ENO2, GFAP
8spec-t439.7GFAP, ENO2
9fluorochrome439.7VIM, CD34
10s 100439.5GFAP, VIM, ENO2
11ganglioside439.5GFAP, VIM, ENO2
12dbc-amp439.5ENO2, VIM, GFAP
13ganciclovir43 1210.5VIM, GFAP
14cytochalasin d43 5910.5NF1, NF2, VIM
15bromodeoxyuridine439.5ENO2, VIM, GFAP
165-hydroxytryptamine439.5GFAP, VIM, ENO2
17choline43 24 1211.5ENO2, VIM, GFAP
18formaldehyde43 2410.5GFAP, VIM, ENO2
19gaba439.4GFAP, VIM, ENO2
20acth439.4ENO2, B3GAT1, GFAP
21tetrodotoxin43 59 2811.4ENO2, GFAP
22nmda43 2810.4GFAP, VIM, ENO2
23rapamycin439.4NF1, NF2, VIM
24acetylcholine43 49 28 24 1213.4GFAP, VIM, ENO2
25methylcellulose439.4CD34, ENO2
26glycogen43 2410.3GFAP, VIM, ENO2
27methionine439.3GFAP, VIM, NF1
28glutamine439.3ENO2, VIM, GFAP
29iron43 2410.2GFAP, VIM, ENO2
30reticulin439.2CD34, VIM, GFAP
31lactate439.2ENO2, VIM, GFAP
32testosterone43 59 24 1212.1GFAP, VIM, B3GAT1, ENO2
33silver439.0GFAP, ENO2, CD34
34arginine439.0GFAP, VIM, NF1, B3GAT1
35forskolin43 49 1210.9ENO2, NF1, VIM, GFAP
36adenylate438.9GFAP, VIM, NF1, ENO2
37cysteine438.8NF1, NF2, VIM, GFAP
38agar438.8GFAP, VIM, NF2, CD34
39dopamine43 28 24 1211.8GFAP, NF1, ENO2
40atp43 289.8ENO2, NF1, VIM, GFAP
41hematoxylin438.7CD34, ENO2, VIM, GFAP
42vegf438.6CD34, ENO2, VIM, GFAP
43lipid438.6ENO2, NF1, VIM, GFAP
44alanine438.5ENO2, B3GAT1, NF1, VIM, GFAP
45thymidine43 249.3CD34, ENO2, GFAP
46retinoic acid43 249.1GFAP, VIM, NF1, ENO2, CD34
47tyrosine437.9GFAP, NF2, NF1, ENO2, CD34
48estrogen437.7GFAP, VIM, NF1, B3GAT1, ENO2, CD34
49paraffin437.7GFAP, VIM, NF2, NF1, ENO2, CD34
50progesterone43 28 59 24 1211.3CD34, GFAP, VIM, NF2, NF1, B3GAT1

GO Terms for genes affiliated with Neurilemmoma

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Cellular components related to Neurilemmoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00057377.4CD34, NF1, NF2, MYH8, VIM, GFAP

Biological processes related to Neurilemmoma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:00600209.8VIM, GFAP
2astrocyte developmentGO:00140029.8VIM, GFAP
3intermediate filament organizationGO:00451099.8VIM, GFAP
4muscle filament slidingGO:00300499.7MYH8, VIM
5negative regulation of neuron projection developmentGO:00109779.6VIM, GFAP
6negative regulation of cell-matrix adhesionGO:00019539.6NF1, NF2
7negative regulation of MAPK cascadeGO:00434099.5NF2, NF1
8negative regulation of cell migrationGO:00303369.4NF1, NF2
9negative regulation of protein kinase activityGO:00064699.1NF1, NF2

Products for genes affiliated with Neurilemmoma

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Sources for Neurilemmoma

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3CDC
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25ICD10
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27ICD9CM
28IUPHAR
29KEGG
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