MCID: NRL005
MIFTS: 58

Neurilemmoma malady

Rare diseases, Cancer diseases categories
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Summaries for Neurilemmoma

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NIH Rare Diseases:42 Schwannomas are tumors of the tissue that covers the nerves (nerve sheath). these tumors develop from a type of cell called a schwann cell, which gives them their name. they are usually benign (not cancerous). although schwannomas can arise from any nerve in the body, the most common areas include the nerves of the head and neck and those involved with flexing in the upper and lower extremities. common symptoms include a slow-growing mass and tinel shock (an electric-like shock when the affected area is touched). the cause of schwannomas is unknown, but they sometimes occur in people with certain disorders including some types of neurofibromatosis. benign schwannomas are typically treated with surgery. last updated: 11/11/2014

MalaCards based summary: Neurilemmoma, also known as schwannoma, is related to acoustic neuroma and paraganglioma. An important gene associated with Neurilemmoma is MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal), and among its related pathways are Striated Muscle Contraction and Neuroscience. The compounds eosin and toluidine have been mentioned in the context of this disorder. Affiliated tissues include tongue, bone and thyroid, and related mouse phenotypes are respiratory system and vision/eye.

Wikipedia:65 A schwannoma (also known as an \"neurilemoma,\" \"neuroma,\" \"neurolemoma,\" and \"Schwann cell... more...

Aliases & Classifications for Neurilemmoma

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Neurilemmoma, Aliases & Descriptions:

Name: Neurilemmoma 8 10 62
Schwannoma 8 42 44
Psammomatous Schwannoma 8 62
Plexiform Schwannoma 42 62
 
Melanotic Schwannoma 42 62
Cellular Schwannoma 42 62
Neurilemoma 42
Neurinoma 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


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Disease Ontology8 DOID:3192
MeSH34 D009442
NCIt39 C3269

Related Diseases for Neurilemmoma

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Diseases related to Neurilemmoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 311)
idRelated DiseaseScoreTop Affiliating Genes
1acoustic neuroma30.7NF1, NF2
2paraganglioma30.7VIM
3granular cell tumor30.7ENO2, VIM
4neurofibrosarcoma30.7NF2, NF1
5angiosarcoma30.6VIM, CD34
6perineurioma30.5CD34, VIM
7spinal cord ependymoma30.5NF2
8fibroma30.5VIM, CD34
9chondrosarcoma30.3ENO2, VIM
10malignant peripheral nerve sheath tumor30.3B3GAT1, NF1
11chordoma30.2VIM, GFAP
12choroid plexus papilloma30.2GFAP
13neurofibroma30.2CD34, NF2, NF1, VIM
14neuroectodermal tumor30.2NF1, ENO2
15rhabdoid tumor30.2SMARCB1, VIM
16hemangiopericytoma30.1CD34, VIM
17neurofibromatosis30.1NF2, NF1
18multiple endocrine neoplasia30.0NF2, NF1
19malignant mesothelioma30.0VIM, NF2
20hemangioma30.0CD34, NF1
21pleomorphic adenoma30.0GFAP, VIM
22hemangioblastoma30.0GFAP, ENO2
23pilocytic astrocytoma29.9GFAP, NF1
24gastrointestinal stromal tumor29.9NF2, NF1, CD34, ENO2, VIM
25ganglioneuroma29.8GFAP, ENO2
26leiomyoma29.8CD34, VIM
27rhabdomyosarcoma29.8VIM, SMARCB1, ENO2
28ganglioglioma29.7ENO2, GFAP
29leiomyosarcoma29.6ENO2, CD34, SMARCB1, VIM
30adenocarcinoma29.6NF2, VIM, ENO2, CD34
31ependymoma29.6GFAP, VIM, NF2, NF1, ENO2
32meningioma29.4VIM, GFAP, CD34, NF2, SMARCB1, NF1
33glioblastoma29.3GFAP, SMARCB1, NF1
34melanoma29.3CD34, ENO2, NF1, NF2, VIM
35astrocytoma29.3VIM, GFAP, NF2, NF1, B3GAT1
36sarcoma29.2ENO2, SMARCB1, NF1, NF2, CD34, B3GAT1
37retinoblastoma29.2GFAP, ENO2, NF1, SMARCB1
38carney complex10.6
39cervicitis10.6
40secretory meningioma10.5VIM
41metanephric adenoma10.5B3GAT1
42epithelioid sarcoma10.5SMARCB1
43congenital mesoblastic nephroma10.5SMARCB1
44cerebral primitive neuroectodermal tumor10.4ENO2
45fibrous histiocytoma10.4CD34
46epulis10.4ENO2
47hydrocephalus10.3
48myoblastoma10.3
49giant cell glioblastoma10.3GFAP
50mediastinal neurilemmoma10.3

Graphical network of the top 20 diseases related to Neurilemmoma:



Diseases related to neurilemmoma

Symptoms for Neurilemmoma

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Drugs & Therapeutics for Neurilemmoma

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Drug clinical trials:

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Genetic Tests for Neurilemmoma

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Anatomical Context for Neurilemmoma

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MalaCards organs/tissues related to Neurilemmoma:

32
Tongue, Bone, Thyroid, Breast, Lymph node, Kidney, Tonsil, Skin, Cervix, Spinal cord, Heart, Skeletal muscle, Colon, Liver, Lung, Salivary gland, Ovary, Testis, Trachea, Appendix

Animal Models for Neurilemmoma or affiliated genes

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MGI Mouse Phenotypes related to Neurilemmoma:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.6ENO2, NF1, NF2, VIM
2MP:00053918.3SMARCB1, GFAP, VIM, NF2, NF1
3MP:00020068.1SMARCB1, NF2, NF1, CD34
4MP:00053867.8GFAP, VIM, NF2, NF1, B3GAT1, ENO2
5MP:00036317.4ENO2, B3GAT1, NF1, NF2, VIM, GFAP
6MP:00053877.4SMARCB1, GFAP, VIM, NF2, NF1, CD34
7MP:00053847.2SMARCB1, GFAP, VIM, NF1, ENO2, CD34
8MP:00053767.0SMARCB1, GFAP, VIM, NF2, NF1, CD34

Publications for Neurilemmoma

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Articles related to Neurilemmoma:

(show top 50)    (show all 424)
idTitleAuthorsYear
1
Laparoscopic phrenectomy for a diaphragmatic neurilemmoma. (24250705)
2013
2
Value of ultrasonography in neurilemmoma diagnosis: the role of round shape morphology. (22957323)
2012
3
Giant neurilemmoma of the vagus nerve: a case report and review of literature. (23936960)
2012
4
Wagner-Meissner neurilemmoma of the right cheek. (18486897)
2008
5
Thigh pain due to intraspinal neurilemmoma. (12932385)
2003
6
Cerebral infarction due to carotid occlusion caused by cervical vagal neurilemmoma: report of a case. (11988627)
2002
7
Solitary cellular schwannoma (neurilemmoma) showing malignant changes: evaluation through magnetic resonance imaging (M.R.I.), surgical intervention, and histopathology. (10209928)
1999
8
A painful subcutaneous neurilemmoma attached to a peripheral nerve. (9448222)
1998
9
Intraosseous neurilemmoma of the fibula. (9040146)
1997
10
Jugular foramen neurilemmoma mimicking an intra-axial brainstem tumor--a case report. (8843014)
1996
11
Neurilemmoma of the posterior tibial nerve with an uncommon case presentation. (1619219)
1992
12
Neurilemmoma in the maxillary alveolar bone: report of a case. (1873292)
1991
13
A rare endobronchial neurilemmoma (Schwannoma). (2914500)
1989
14
Polypoid neurilemmoma of the trachea: an unusual cause of major airway obstruction. (3250429)
1988
15
A combined neurilemmoma and angioma of the parasellar region. Case report. (3598695)
1987
16
Pathologic quiz case 2. Neurilemmoma (schwannoma). (3675901)
1987
17
Plexiform neurilemmoma: a clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. (3114942)
1987
18
Anterior uveal neurilemmoma--a rare neoplasm simulating malignant melanoma. (3545285)
1987
19
Tapia's syndrome caused by a neurilemmoma of vagus and hypoglossal nerves in the neck. (3799257)
1986
20
Gastric neurilemmoma: case report. (3878467)
1985
21
Spinal subdural hematoma, neurilemmoma, and acute transverse myelopathy. (3975824)
1985
22
Epithelioid neurilemmoma of the trigeminal nerve: an immunohistochemical and ultrastructural study. (3913635)
1985
23
Atypical central neurilemmoma of the mandible. (3856819)
1985
24
Mesenchymal differentiation in trigeminal neurilemmoma. (7116288)
1982
25
Regional Multiplicity of a neurilemmoma. (7061018)
1982
26
Neurilemmoma of the pterygo-maxillary fossa. (7229524)
1981
27
Neurilemmoma of optic nerve. (7216356)
1980
28
Neurilemmoma of the vagus nerve. (7212623)
1980
29
Multicentric thyroid carcinoma, parathyroid adenomas, and vagal neurilemmoma in a young man with antecedent tonsillar radiation. (7412405)
1980
30
Neurilemmoma of the foot: a case report. (762394)
1979
31
Trigger finger due to neurilemmoma in the carpal tunnel. (738662)
1978
32
Retroperitoneal neurilemmoma. (675931)
1978
33
Tarsal-tunnel syndrome caused by neurilemmoma of the medial plantar nerve. A case report. (833162)
1977
34
Endocystography in cystic neurilemmoma. (876448)
1977
35
Calcification within a thoracic neurilemmoma. (4444769)
1974
36
Neurilemmoma of the pharynx. (5021025)
1972
37
Intraparotid facial neurilemmoma. (5443951)
1970
38
Malignant neurilemmoma of parotid gland. (5491649)
1970
39
Pulmonary neurilemmoma. (5476293)
1970
40
Neurilemmoma of the cheek. Report of a case. (5230128)
1967
41
NEURILEMMOMA OF THE FACIAL NERVE. (14119586)
1964
42
Neurilemmoma of the cervical sympathetic chain. (14024784)
1963
43
Palpebral neurilemmoma. (14422917)
1960
44
The neurosurgical aspects of seventh nerve neurilemmoma. (13825709)
1960
45
Neurilemmoma of the diaphragm causing severe hypertrophic pulmonary osteoarthropathy. (13560782)
1958
46
Neurilemmoma of the diaphragm. (13320560)
1956
47
Neurilemmoma of the sigmoid colon, associated with diverticulitis as a cause of obstruction. (14388189)
1955
48
Neurilemmoma (Schwannoma) of the larynx. (13136231)
1953
49
Neurilemmoma of pharynx. (12996927)
1952
50
Neurilemmoma of the pharynx. (20266777)
1947

Variations for Neurilemmoma

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Expression for genes affiliated with Neurilemmoma

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Expression patterns in normal tissues for genes affiliated with Neurilemmoma

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Pathways for genes affiliated with Neurilemmoma

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Pathways related to Neurilemmoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8MYH8, VIM
29.0ENO2, NF2, GFAP
3
Show member pathways
8.7NF1, MYH8, VIM, GFAP

Compounds for genes affiliated with Neurilemmoma

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Compounds related to Neurilemmoma according to GeneCards/GeneDecks:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1eosin4410.0VIM, GFAP
2toluidine4410.0ENO2, VIM
3retinaldehyde4410.0VIM, GFAP
4silicone449.9VIM, GFAP
5streptozotocin449.8VIM, GFAP
6homovanillic acid44 2410.8GFAP, ENO2
72-mercaptoethanol449.8ENO2, GFAP
8spec-t449.7GFAP, ENO2
9fluorochrome449.7VIM, CD34
10s 100449.5GFAP, VIM, ENO2
11ganglioside449.5GFAP, VIM, ENO2
12dbc-amp449.5ENO2, VIM, GFAP
13ganciclovir44 1110.5VIM, GFAP
14cytochalasin d44 6110.5NF1, NF2, VIM
15bromodeoxyuridine449.5ENO2, VIM, GFAP
165-hydroxytryptamine449.5GFAP, VIM, ENO2
17choline44 24 1111.5ENO2, VIM, GFAP
18formaldehyde44 2410.5GFAP, VIM, ENO2
19gaba449.4GFAP, VIM, ENO2
20acth449.4ENO2, B3GAT1, GFAP
21tetrodotoxin44 61 2811.4ENO2, GFAP
22nmda44 2810.4GFAP, VIM, ENO2
23rapamycin449.4NF1, NF2, VIM
24acetylcholine44 50 28 24 1113.4GFAP, VIM, ENO2
25methylcellulose449.4CD34, ENO2
26glycogen44 2410.3GFAP, VIM, ENO2
27methionine449.3GFAP, VIM, NF1
28glutamine449.3ENO2, VIM, GFAP
29iron44 2410.2GFAP, VIM, ENO2
30reticulin449.2CD34, VIM, GFAP
31lactate449.2ENO2, VIM, GFAP
32testosterone44 61 24 1112.1GFAP, VIM, B3GAT1, ENO2
33silver449.0GFAP, ENO2, CD34
34arginine449.0GFAP, VIM, NF1, B3GAT1
35forskolin44 50 1110.9ENO2, NF1, VIM, GFAP
36adenylate448.9GFAP, VIM, NF1, ENO2
37cysteine448.8NF1, NF2, VIM, GFAP
38agar448.8GFAP, VIM, NF2, CD34
39dopamine44 28 24 1111.8GFAP, NF1, ENO2
40atp44 289.8ENO2, NF1, VIM, GFAP
41hematoxylin448.7CD34, ENO2, VIM, GFAP
42vegf448.6CD34, ENO2, VIM, GFAP
43lipid448.6ENO2, NF1, VIM, GFAP
44alanine448.5ENO2, B3GAT1, NF1, VIM, GFAP
45thymidine44 249.3CD34, ENO2, GFAP
46retinoic acid44 249.1GFAP, VIM, NF1, ENO2, CD34
47tyrosine447.9GFAP, NF2, NF1, ENO2, CD34
48estrogen447.7GFAP, VIM, NF1, B3GAT1, ENO2, CD34
49paraffin447.7GFAP, VIM, NF2, NF1, ENO2, CD34
50progesterone44 28 61 24 1111.3CD34, GFAP, VIM, NF2, NF1, B3GAT1

GO Terms for genes affiliated with Neurilemmoma

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Cellular components related to Neurilemmoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:0057377.4CD34, NF1, NF2, MYH8, VIM, GFAP

Biological processes related to Neurilemmoma according to GeneCards/GeneDecks:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:0600209.8VIM, GFAP
2astrocyte developmentGO:0140029.8VIM, GFAP
3intermediate filament organizationGO:0451099.8VIM, GFAP
4muscle filament slidingGO:0300499.7MYH8, VIM
5negative regulation of neuron projection developmentGO:0109779.6VIM, GFAP
6negative regulation of cell-matrix adhesionGO:0019539.6NF1, NF2
7negative regulation of MAPK cascadeGO:0434099.5NF2, NF1
8negative regulation of cell migrationGO:0303369.4NF1, NF2
9negative regulation of protein kinase activityGO:0064699.1NF1, NF2

Products for genes affiliated with Neurilemmoma

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Sources for Neurilemmoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet