MCID: NRL005
MIFTS: 50

Neurilemmoma malady

Rare diseases, Neuronal diseases categories

Aliases & Classifications for Neurilemmoma

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Aliases & Descriptions for Neurilemmoma:

Name: Neurilemmoma 8 10 61
Schwannoma 8 42 44
Plexiform Schwannoma 42 61
Cellular Schwannoma 42 61
Acoustic Neuroma 42 61
Psammomatous Schwannoma 8
Melanotic Neurilemmoma 61
 
Vestibular Schwannoma 42
Acoustic Neurilemoma 42
Melanotic Schwannoma 42
Acoustic Neurinoma 42
Neurilemoma 42
Neurinoma 42


Classifications:



External Ids:

Disease Ontology8 DOID:3192
MeSH33 D009442
NCIt39 C3269

Summaries for Neurilemmoma

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NIH Rare Diseases:42 Schwannomas are tumors of the tissue that covers the nerves (nerve sheath). these tumors develop from a type of cell called a schwann cell, which gives these tumors their name. they are usually benign (not cancerous). although schwannomas can arise from any nerve in the body, the most common areas include the nerves of the head and neck and those involved with moving the arms and legs. common symptoms include a slow-growing mass and tinel's sign (an electric-like shock when the affected area is touched). the cause of schwannomas is unknown, but they sometimes occur in people with certain disorders including some types of neurofibromatosis. benign schwannomas are typically treated with surgery. last updated: 3/9/2015

MalaCards based summary: Neurilemmoma, also known as schwannoma, is related to neurofibromatosis, type 2 and spinal cord ependymoma. An important gene associated with Neurilemmoma is MYH8 (myosin, heavy chain 8, skeletal muscle, perinatal), and among its related pathways are Striated Muscle Contraction and Neuroscience. The compounds eosin and toluidine have been mentioned in the context of this disorder. Affiliated tissues include tongue, bone and thyroid, and related mouse phenotypes are respiratory system and vision/eye.

Wikipedia:64 A schwannoma (also known as an \"neurilemoma,\" \"neuroma,\" \"neurolemoma,\" and \"Schwann cell... more...

Related Diseases for Neurilemmoma

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Diseases related to Neurilemmoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 323)
idRelated DiseaseScoreTop Affiliating Genes
1neurofibromatosis, type 231.1NF1, NF2
2spinal cord ependymoma30.9NF2
3malignant peripheral nerve sheath tumor30.7B3GAT1, NF1
4choroid plexus papilloma30.7GFAP
5granular cell tumor30.7VIM, ENO2
6neurofibrosarcoma30.6NF2, NF1
7angiosarcoma30.6VIM, CD34
8perineurioma30.5VIM, CD34
9acoustic neuroma30.5NF1, NF2
10fibroma30.5VIM, CD34
11glomus tumor30.5VIM
12neuroectodermal tumor30.4NF1, ENO2
13tanycytic ependymoma30.4NF2, GFAP
14chondrosarcoma30.3ENO2, VIM
15neurofibroma30.3VIM, NF2, NF1, CD34
16chordoma30.2GFAP, VIM
17rhabdoid tumor30.2VIM, SMARCB1
18hemangioblastoma30.2GFAP, ENO2
19glioblastoma30.2NF1, GFAP, SMARCB1
20ganglioneuroma30.1ENO2, GFAP
21hemangiopericytoma30.1CD34, VIM
22neurofibromatosis30.1NF1, NF2
23leiomyoma30.0VIM, CD34
24multiple endocrine neoplasia30.0NF1, NF2
25hemangioma30.0CD34, NF1
26pleomorphic adenoma30.0VIM, GFAP
27pilocytic astrocytoma29.9NF1, GFAP
28mesothelioma29.9CD34, NF2, VIM
29gastrointestinal stromal tumor29.9VIM, NF2, NF1, ENO2, CD34
30neuroendocrine tumor29.8ENO2, NF1
31rhabdomyosarcoma29.8SMARCB1, VIM, ENO2
32ependymoma29.8GFAP, VIM, NF2, NF1, ENO2
33adenocarcinoma29.7VIM, NF2, ENO2, CD34
34ganglioglioma29.7GFAP, ENO2
35paraganglioma29.7GFAP, NF1, ENO2
36leiomyosarcoma29.6CD34, ENO2, VIM, SMARCB1
37retinoblastoma29.6SMARCB1, GFAP, NF1, ENO2
38melanoma29.3VIM, NF2, NF1, ENO2, CD34
39astrocytoma29.3GFAP, VIM, NF2, NF1, B3GAT1
40sarcoma29.2SMARCB1, VIM, NF2, NF1, B3GAT1, ENO2
41cerebrospinal fluid leak10.7
42headache10.7
43banf acoustic neurinoma10.6
44cervicitis10.6
45meningitis10.5
46metanephric adenoma10.5B3GAT1
47secretory meningioma10.5VIM
48hydrocephalus10.5
49epithelioid sarcoma10.5SMARCB1
50congenital mesoblastic nephroma10.5SMARCB1

Graphical network of the top 20 diseases related to Neurilemmoma:



Diseases related to neurilemmoma

Symptoms for Neurilemmoma

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Drugs & Therapeutics for Neurilemmoma

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Drug clinical trials:

Search ClinicalTrials for Neurilemmoma

Search NIH Clinical Center for Neurilemmoma

Genetic Tests for Neurilemmoma

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Anatomical Context for Neurilemmoma

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MalaCards organs/tissues related to Neurilemmoma:

31
Tongue, Bone, Thyroid, Breast, Lymph node, Kidney, Tonsil, Skin, Cervix, Spinal cord, Heart, Skeletal muscle, Colon, Liver, Lung, Salivary gland, Ovary, Testis, Trachea, Appendix

Animal Models for Neurilemmoma or affiliated genes

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MGI Mouse Phenotypes related to Neurilemmoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053888.6ENO2, NF1, NF2, VIM
2MP:00053918.3SMARCB1, GFAP, VIM, NF2, NF1
3MP:00020068.1SMARCB1, NF2, NF1, CD34
4MP:00053867.8GFAP, VIM, NF2, NF1, B3GAT1, ENO2
5MP:00036317.4ENO2, B3GAT1, NF1, NF2, VIM, GFAP
6MP:00053877.4SMARCB1, GFAP, VIM, NF2, NF1, CD34
7MP:00053847.2SMARCB1, GFAP, VIM, NF1, ENO2, CD34
8MP:00053767.0SMARCB1, GFAP, VIM, NF2, NF1, CD34

Publications for Neurilemmoma

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Articles related to Neurilemmoma:

(show top 50)    (show all 431)
idTitleAuthorsYear
1
Intraosseous neurilemmoma of the proximal ulna. (25460435)
2014
2
Laparoscopic phrenectomy for a diaphragmatic neurilemmoma. (24250705)
2013
3
Value of ultrasonography in neurilemmoma diagnosis: the role of round shape morphology. (22957323)
2012
4
Giant neurilemmoma of the vagus nerve: a case report and review of literature. (23936960)
2012
5
Wagner-Meissner neurilemmoma of the right cheek. (18486897)
2008
6
Thigh pain due to intraspinal neurilemmoma. (12932385)
2003
7
Cerebral infarction due to carotid occlusion caused by cervical vagal neurilemmoma: report of a case. (11988627)
2002
8
A painful subcutaneous neurilemmoma attached to a peripheral nerve. (9448222)
1998
9
Intraosseous neurilemmoma of the fibula. (9040146)
1997
10
Jugular foramen neurilemmoma mimicking an intra-axial brainstem tumor--a case report. (8843014)
1996
11
Neurilemmoma of the posterior tibial nerve with an uncommon case presentation. (1619219)
1992
12
Neurilemmoma in the maxillary alveolar bone: report of a case. (1873292)
1991
13
A rare endobronchial neurilemmoma (Schwannoma). (2914500)
1989
14
Polypoid neurilemmoma of the trachea: an unusual cause of major airway obstruction. (3250429)
1988
15
A combined neurilemmoma and angioma of the parasellar region. Case report. (3598695)
1987
16
Pathologic quiz case 2. Neurilemmoma (schwannoma). (3675901)
1987
17
Plexiform neurilemmoma: a clinicopathological and immunohistochemical analysis of 23 tumours from 20 patients. (3114942)
1987
18
Anterior uveal neurilemmoma--a rare neoplasm simulating malignant melanoma. (3545285)
1987
19
Tapia's syndrome caused by a neurilemmoma of vagus and hypoglossal nerves in the neck. (3799257)
1986
20
Gastric neurilemmoma: case report. (3878467)
1985
21
Spinal subdural hematoma, neurilemmoma, and acute transverse myelopathy. (3975824)
1985
22
Epithelioid neurilemmoma of the trigeminal nerve: an immunohistochemical and ultrastructural study. (3913635)
1985
23
Atypical central neurilemmoma of the mandible. (3856819)
1985
24
Mesenchymal differentiation in trigeminal neurilemmoma. (7116288)
1982
25
Regional Multiplicity of a neurilemmoma. (7061018)
1982
26
Neurilemmoma of the pterygo-maxillary fossa. (7229524)
1981
27
Neurilemmoma of optic nerve. (7216356)
1980
28
Neurilemmoma of the vagus nerve. (7212623)
1980
29
Neurilemmoma of the foot: a case report. (762394)
1979
30
Trigger finger due to neurilemmoma in the carpal tunnel. (738662)
1978
31
Retroperitoneal neurilemmoma. (675931)
1978
32
Tarsal-tunnel syndrome caused by neurilemmoma of the medial plantar nerve. A case report. (833162)
1977
33
Endocystography in cystic neurilemmoma. (876448)
1977
34
Neurilemmoma (schwannoma) of the larynx. (1123570)
1975
35
Calcification within a thoracic neurilemmoma. (4444769)
1974
36
Neurilemmoma of the pharynx. (5021025)
1972
37
Intraparotid facial neurilemmoma. (5443951)
1970
38
Malignant neurilemmoma of parotid gland. (5491649)
1970
39
Pulmonary neurilemmoma. (5476293)
1970
40
Neurilemmoma of the cheek. Report of a case. (5230128)
1967
41
NEURILEMMOMA OF THE FACIAL NERVE. (14119586)
1964
42
Neurilemmoma of the cervical sympathetic chain. (14024784)
1963
43
Palpebral neurilemmoma. (14422917)
1960
44
The neurosurgical aspects of seventh nerve neurilemmoma. (13825709)
1960
45
Neurilemmoma of the diaphragm causing severe hypertrophic pulmonary osteoarthropathy. (13560782)
1958
46
Neurilemmoma of the diaphragm. (13320560)
1956
47
Neurilemmoma of the sigmoid colon, associated with diverticulitis as a cause of obstruction. (14388189)
1955
48
Neurilemmoma (Schwannoma) of the larynx. (13136231)
1953
49
Neurilemmoma of pharynx. (12996927)
1952
50
Neurilemmoma of the pharynx. (20266777)
1947

Variations for Neurilemmoma

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Expression for genes affiliated with Neurilemmoma

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Search GEO for disease gene expression data for Neurilemmoma.

Pathways for genes affiliated with Neurilemmoma

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Pathways related to Neurilemmoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.8MYH8, VIM
29.0ENO2, NF2, GFAP
3
Show member pathways
8.7NF1, MYH8, VIM, GFAP

Compounds for genes affiliated with Neurilemmoma

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Compounds related to Neurilemmoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 56)
idCompoundScoreTop Affiliating Genes
1eosin4410.0GFAP, VIM
2toluidine4410.0ENO2, VIM
3retinaldehyde4410.0GFAP, VIM
4silicone449.9VIM, GFAP
5streptozotocin449.8VIM, GFAP
6homovanillic acid44 2410.8ENO2, GFAP
72-mercaptoethanol449.8GFAP, ENO2
8spec-t449.7GFAP, ENO2
9fluorochrome449.7VIM, CD34
10s 100449.5VIM, ENO2, GFAP
11ganglioside449.5GFAP, VIM, ENO2
12dbc-amp449.5ENO2, GFAP, VIM
13ganciclovir44 1110.5GFAP, VIM
14cytochalasin d44 6010.5NF2, VIM, NF1
15bromodeoxyuridine449.5VIM, ENO2, GFAP
165-hydroxytryptamine449.5ENO2, GFAP, VIM
17choline44 24 1111.5ENO2, VIM, GFAP
18formaldehyde44 2410.5VIM, GFAP, ENO2
19gaba449.4ENO2, VIM, GFAP
20acth449.4B3GAT1, GFAP, ENO2
21tetrodotoxin44 60 2811.4ENO2, GFAP
22nmda44 2810.4GFAP, ENO2, VIM
23rapamycin449.4NF1, VIM, NF2
24acetylcholine44 50 28 24 1113.4VIM, GFAP, ENO2
25methylcellulose449.4ENO2, CD34
26glycogen44 2410.3VIM, GFAP, ENO2
27methionine449.3GFAP, VIM, NF1
28glutamine449.3ENO2, GFAP, VIM
29iron44 2410.2VIM, GFAP, ENO2
30reticulin449.2CD34, GFAP, VIM
31lactate449.2ENO2, VIM, GFAP
32testosterone44 60 24 1112.1ENO2, B3GAT1, VIM, GFAP
33silver449.0GFAP, ENO2, CD34
34arginine449.0VIM, NF1, B3GAT1, GFAP
35forskolin44 50 1110.9NF1, ENO2, VIM, GFAP
36adenylate448.9NF1, VIM, ENO2, GFAP
37cysteine448.8GFAP, VIM, NF2, NF1
38agar448.8NF2, GFAP, VIM, CD34
39dopamine44 28 24 1111.8NF1, GFAP, ENO2
40atp44 289.8GFAP, VIM, NF1, ENO2
41hematoxylin448.7ENO2, GFAP, VIM, CD34
42vegf448.6CD34, VIM, GFAP, ENO2
43lipid448.6NF1, ENO2, VIM, GFAP
44alanine448.5ENO2, GFAP, B3GAT1, VIM, NF1
45thymidine44 249.3GFAP, CD34, ENO2
46retinoic acid44 249.1ENO2, CD34, NF1, GFAP, VIM
47tyrosine447.9NF2, GFAP, CD34, NF1, ENO2
48estrogen447.7VIM, CD34, ENO2, B3GAT1, NF1, GFAP
49paraffin447.7GFAP, NF2, NF1, VIM, CD34, ENO2
50progesterone44 28 60 24 1111.3B3GAT1, CD34, GFAP, ENO2, VIM, NF2

GO Terms for genes affiliated with Neurilemmoma

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Cellular components related to Neurilemmoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00057377.4CD34, NF1, NF2, MYH8, VIM, GFAP

Biological processes related to Neurilemmoma according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1Bergmann glial cell differentiationGO:00600209.8VIM, GFAP
2astrocyte developmentGO:00140029.8VIM, GFAP
3intermediate filament organizationGO:00451099.8VIM, GFAP
4muscle filament slidingGO:00300499.7MYH8, VIM
5negative regulation of neuron projection developmentGO:00109779.6VIM, GFAP
6negative regulation of cell-matrix adhesionGO:00019539.6NF1, NF2
7negative regulation of MAPK cascadeGO:00434099.5NF2, NF1
8negative regulation of cell migrationGO:00303369.4NF1, NF2
9negative regulation of protein kinase activityGO:00064699.1NF1, NF2

Sources for Neurilemmoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet