MCID: NRT004
MIFTS: 49

Neuritis malady

Neuronal diseases category
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Summaries for Neuritis

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Wikipedia:65 Peripheral neuropathy (PN) is damage or disease affecting nerves, which may impair sensation, movement,... more...

MalaCards based summary: Neuritis, also known as neuritis, peripheral, is related to optic neuritis and neuromyelitis optica. An important gene associated with Neuritis is SEPT9 (septin 9), and among its related pathways is Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds sulfatide and 2,3-cyclic nucleotide have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and eye, and related mouse phenotypes are behavior/neurological and vision/eye.

Aliases & Classifications for Neuritis

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Neuritis, Aliases & Descriptions:

Name: Neuritis 8 10 44 62
Neuritis, Peripheral 62
 
Peripheral Neuritis 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


External Ids:

Disease Ontology8 DOID:1803
MeSH34 D009443

Related Diseases for Neuritis

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Diseases related to Neuritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 262)
idRelated DiseaseScoreTop Affiliating Genes
1optic neuritis31.6LTA, PLP1, MOG, AQP4, MPZ
2neuromyelitis optica31.3MOG, AQP4
3multiple sclerosis31.0MPZ, AQP4, MOG, PLP1, LTA
4acute disseminated encephalomyelitis30.8AQP4, MOG
5encephalitis30.7MOG, AQP4
6demyelinating disease30.0MPZ, AQP4, MOG, PLP1
7charcot-marie-tooth disease29.9MPZ, PLP1
8myasthenia gravis29.8LTA, PLP1, MOG
9tetanus29.7LTA, PLP1, MOG, MPZ
10retinitis10.7
11brachial plexus neuritis10.5
12neuropathy10.5
13acute retrobulbar neuritis10.5
14hereditary neuralgic amyotrophy10.5
15brachial plexus neuropathy10.5MPZ
16myelitis10.4
17parsonage turner syndrome10.4
18ischemic optic neuropathy10.4
19systemic lupus erythematosus10.3
20herpes zoster10.3
21lupus erythematosus10.3
22leprosy10.3
23transverse myelitis10.3
24hepatitis10.3
25turner syndrome10.3
26herpes zoster ophthalmicus10.3
27hereditary neuropathies10.3PLP1, MPZ
28influenza10.3
29meningitis10.3
30uveitis10.3
31primary progressive multiple sclerosis10.2PLP1, MOG
32pelizaeus-merzbacher disease10.2MPZ, PLP1
33cervicitis10.2
34measles10.2
35choroiditis10.2
36anterior ischemic optic neuropathy10.2
37papilledema10.2
38mitochondrial disorders10.2MT-ND6, MT-ND4
39leber hereditary optic neuropathy with dystonia10.2MT-ND6, MT-ND4
40central nervous system disease10.2PLP1, MOG
41melas syndrome10.1MT-ND6, MT-ND4
42guillain-barre syndrome10.1PLP1, MOG, MPZ
43scotoma10.1
44meningoencephalitis10.1
45chickenpox10.1
46optic papillitis10.1
47vasculitis10.1
48neurosyphilis10.1
49adrenoleukodystrophy10.1MPZ, MOG, PLP1
50optic nerve disease10.1MT-ND4, MT-ND6

Graphical network of the top 20 diseases related to Neuritis:



Diseases related to neuritis

Symptoms for Neuritis

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Drugs & Therapeutics for Neuritis

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Drug clinical trials:

Search ClinicalTrials for Neuritis

Search NIH Clinical Center for Neuritis

Genetic Tests for Neuritis

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Anatomical Context for Neuritis

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MalaCards organs/tissues related to Neuritis:

32
T cells, Testes, Eye, Brain, Pituitary, Bone, Spinal cord, Heart, Liver, Breast, Myeloid, B cells, Lung, Thyroid, Pons

Animal Models for Neuritis or affiliated genes

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MGI Mouse Phenotypes related to Neuritis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.6LTA, PLP1, MOG, AQP4, MPZ
2MP:00053918.4AQP4, MOG, MT-ND6, PLP1, LTA
3MP:00053978.3MPZ, SEPT9, MOG, PLP1, LTA
4MP:00036317.9MPZ, AQP4, MOG, MT-ND6, PLP1, LTA
5MP:00053847.7MPZ, SEPT9, MOG, MT-ND6, MT-ND2, PLP1
6MP:00053877.6LTA, PLP1, MT-ND2, MOG, AQP4, SEPT9

Publications for Neuritis

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Articles related to Neuritis:

(show top 50)    (show all 915)
idTitleAuthorsYear
1
Mycobacterium w administration for steroid resistant optic neuritis with long-term follow-up. (25231916)
2014
2
Atypical optic neuritis. (25405666)
2014
3
Perineural mast cells are specifically enriched in pancreatic neuritis and neuropathic pain in pancreatic cancer and chronic pancreatitis. (23555989)
2013
4
Numbness over the distribution of trigeminal nerve--trigeminal trophic syndrome or viral neuritis: a diagnostic dilemma! (23851893)
2013
5
Value of the video head impulse test in assessing vestibular deficits following vestibular neuritis. (23539412)
2013
6
Visual field characteristics in neuromyelitis optica in absence of and after one episode of optic neuritis. (23807832)
2013
7
A case of optic neuritis incidentally detected by somatostatin receptor scintigraphy. (24094374)
2013
8
Clinical features of retinal diseases masquerading as retrobulbar optic neuritis. (24033953)
2013
9
Clinical and pathological features of acute optic neuritis in Chinese patients. (23652052)
2013
10
Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) Study. (22967869)
2013
11
Clinical profile of Malay children with optic neuritis. (22520350)
2012
12
Optic neuritis: experience from a south Indian demyelinating disease registry. (23135022)
2012
13
Brachial plexus neuritis in the context of acute HIV seroconversion illness: a case report. (22422693)
2012
14
MR diagnosis of facial neuritis: diagnostic performance of contrast-enhanced 3D-FLAIR technique compared with contrast-enhanced 3D-T1-fast-field echo with fat suppression. (22207300)
2012
15
Orbital Doppler evaluation of blood flow velocities in optic neuritis. (22511838)
2012
16
Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. (22157536)
2012
17
Erythropoietin for acute multiple sclerosis in patients with optic neuritis as a first demyelination event. (22465890)
2012
18
Notes on the use of HBO2 with optic neuritis. (22292262)
2011
19
Vestibular neuritis has selective effects on air- and bone-conducted cervical and ocular vestibular evoked myogenic potentials. (21239223)
2011
20
Facial paralysis and lymphocytic facial neuritis in a rhesus macaque (Macaca mulatta) positive for simian retrovirus type D2. (22330582)
2011
21
Acute anterior uveitis and optic neuritis as ocular complications of influenza A infection in an 11-year-old boy. (21732577)
2011
22
Assessment of outcome predictors after first attack of optic neuritis. (22030428)
2011
23
Brachial neuritis masquerading as acute coronary syndrome. (20838916)
2011
24
Ocular vestibular-evoked myogenic potentials to bone-conducted vibration in superior vestibular neuritis show utricular function. (20647134)
2010
25
Diagnostic validity of optic disc and retinal nerve fiber layer evaluations in detecting structural changes after optic neuritis. (20381872)
2010
26
Retinitis and optic neuritis in a child with chickenpox: case report and review of literature. (20622712)
2010
27
Ethambutol-induced optic neuritis and multiple sclerosis: is there an association? (20843609)
2010
28
A case of secondary syphilis presenting as optic neuritis. (20182899)
2010
29
Early observations on optic neuritis and Uhthoff's sign. (20375511)
2010
30
MS-275, an histone deacetylase inhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis. (20451583)
2010
31
Demyelinating optic neuritis in children. (18936195)
2009
32
The optic neuritis treatment trial: a definitive answer and profound impact with unexpected results. (18625952)
2008
33
Clinical course of optic neuritis in patients with relapsing neuromyelitis optica. (18195212)
2008
34
Relapsing inflammatory optic neuritis: is it neuromyelitis optica? (18505981)
2008
35
Electrophysiological evidence for heterogeneity of lesions in optic neuritis. (17898277)
2007
36
Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. (17719649)
2007
37
Historical perspective and future prospective for retinal nerve fiber loss in optic neuritis and multiple sclerosis. (18049278)
2007
38
Optical coherence tomography in optic neuritis. (17198866)
2007
39
Local phenol injection in the treatment of interdigital neuritis of the foot (Morton's neuroma). (16878772)
2005
40
Differentiating traumatic neuritis from poliomyelitis. (14606778)
2003
41
Chronic inflammatory demyelinating polyradiculoneuropathy with histologically proven optic neuritis. (11484826)
2001
42
Malignant otitis externa with optic neuritis. (9624378)
1998
43
The effects of monoamine reuptake inhibiting antidepressants in experimental allergic neuritis. (10975734)
1997
44
Peptide specificity of anti-myelin basic protein antibodies in patients with acute optic neuritis and the HLA system. (7516573)
1994
45
Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. (7505838)
1993
46
Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis. (1969423)
1990
47
Optic neuritis, transverse myelitis, and anti-DNA antibodies nine years after thymectomy for myasthenia gravis. (6610427)
1984
48
Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis. (4369864)
1974
49
The elimination of non-surgical lesions in brain tumor suspects; pseudo-tumor cerebri, and papilledema without increased intracranial pressure (optic neuritis). (18903109)
1948
50
Ten Cases of Acute Retrobulbar Neuritis. (20772322)
1926

Variations for Neuritis

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Expression for genes affiliated with Neuritis

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Expression patterns in normal tissues for genes affiliated with Neuritis

Search GEO for disease gene expression data for Neuritis.

Pathways for genes affiliated with Neuritis

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Compounds for genes affiliated with Neuritis

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Sources:
44Novoseek, 11DrugBank, 50PharmGKB, 28IUPHAR, 24HMDB
See all sources

Compounds related to Neuritis according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1sulfatide449.9MPZ, PLP1
22,3-cyclic nucleotide449.7PLP1, MOG, MPZ
3glatiramer acetate44 1110.7MPZ, MOG, PLP1
4silver449.7PLP1, MOG
5acetylcholine44 50 28 24 1113.3MOG, PLP1, LTA
6isoleucine449.3MT-ND6, MT-ND4
7glutamate449.1LTA, PLP1, AQP4, MPZ
8Ubiquinol 8248.9MT-ND2, MT-ND6, MT-ND4
9Sulfide248.9MT-ND2, MT-ND6, MT-ND4
10QH2248.9MT-ND2, MT-ND6, MT-ND4
11Ubiquinone Q2248.9MT-ND4, MT-ND6, MT-ND2
12Ubiquinone Q1248.9MT-ND2, MT-ND6, MT-ND4
13FAD248.8MT-ND2, MT-ND6, MT-ND4
14valine448.8MT-ND2, MT-ND6, MT-ND4
15nad28 249.8MT-ND2, MT-ND6, MT-ND4
16methionine448.7MPZ, MT-ND6, MT-ND2, PLP1
17glucose448.5MOG, MT-ND4, MT-CO3, LTA
18oxygen44 249.4LTA, MT-ND2, MT-ND6, MOG
19lipid448.3MPZ, MOG, MT-ND2, PLP1, LTA
20iron44 249.3MT-ND2, MT-ND6, MT-ND4
21nadh44 24 1110.3MT-ND2, MT-ND6, MT-CO3, MT-ND4

GO Terms for genes affiliated with Neuritis

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Cellular components related to Neuritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:0432099.7PLP1, MPZ

Products for genes affiliated with Neuritis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Neuritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet