MCID: NRT004
MIFTS: 48

Neuritis malady

Neuronal diseases category
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Summaries for Neuritis

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Sources:
65Wikipedia, 33MalaCards
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Wikipedia:65 Peripheral neuropathy (PN) is damage or disease affecting nerves, which may impair sensation, movement,... more...

MalaCards: Neuritis, also known as peripheral neuritis, is related to optic neuritis and multiple sclerosis. An important gene associated with Neuritis is SEPT9 (septin 9), and among its related pathways is Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.. The compounds sulfatide and 2,3-cyclic nucleotide have been mentioned in the context of this disorder. Affiliated tissues include t cells, testes and brain, and related mouse phenotypes are behavior/neurological and vision/eye.

Aliases & Classifications for Neuritis

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Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

neuritis 8 10 45 62
peripheral neuritis 8


External Ids:

Disease Ontology8 DOID:1803
MeSH35 D009443

Related Diseases for Neuritis

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Neuritis:



Diseases related to neuritis

Symptoms for Neuritis

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Drugs & Therapeutics for Neuritis

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Neuritis

Search NIH Clinical Center for Neuritis

Genetic Tests for Neuritis

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Anatomical Context for Neuritis

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Sources:
33MalaCards
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MalaCards organs/tissues related to Neuritis:

33
T cells, Testes, Brain, Eye, Pituitary, Bone, Liver, B cells, Myeloid, Breast, Heart, Spinal cord, Lung, Pons

Animal Models for Neuritis or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Neuritis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.6LTA, PLP1, MOG, AQP4, MPZ
2MP:00053918.4AQP4, MOG, MT-ND6, PLP1, LTA
3MP:00053978.3MPZ, SEPT9, MOG, PLP1, LTA
4MP:00036317.9MPZ, AQP4, MOG, MT-ND6, PLP1, LTA
5MP:00053847.7MPZ, SEPT9, MOG, MT-ND6, MT-ND2, PLP1
6MP:00053877.6LTA, PLP1, MT-ND2, MOG, AQP4, SEPT9

Publications for Neuritis

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52PubMed
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Articles related to Neuritis:

(show top 50)    (show all 874)
idTitleAuthorsYear
1
Perineural mast cells are specifically enriched in pancreatic neuritis and neuropathic pain in pancreatic cancer and chronic pancreatitis. (23555989)
2013
2
Numbness over the distribution of trigeminal nerve--trigeminal trophic syndrome or viral neuritis: a diagnostic dilemma! (23851893)
2013
3
Value of the video head impulse test in assessing vestibular deficits following vestibular neuritis. (23539412)
2013
4
Visual field characteristics in neuromyelitis optica in absence of and after one episode of optic neuritis. (23807832)
2013
5
A case of optic neuritis incidentally detected by somatostatin receptor scintigraphy. (24094374)
2013
6
Clinical features of retinal diseases masquerading as retrobulbar optic neuritis. (24033953)
2013
7
Clinical and pathological features of acute optic neuritis in Chinese patients. (23652052)
2013
8
Initiation of anti-TNF therapy and the risk of optic neuritis: from the safety assessment of biologic ThERapy (SABER) Study. (22967869)
2013
9
Clinical profile of Malay children with optic neuritis. (22520350)
2012
10
Optic neuritis: experience from a south Indian demyelinating disease registry. (23135022)
2012
11
Brachial plexus neuritis in the context of acute HIV seroconversion illness: a case report. (22422693)
2012
12
MR diagnosis of facial neuritis: diagnostic performance of contrast-enhanced 3D-FLAIR technique compared with contrast-enhanced 3D-T1-fast-field echo with fat suppression. (22207300)
2012
13
Relationship between NMO-antibody and anti-MOG antibody in optic neuritis. (22157536)
2012
14
Erythropoietin for acute multiple sclerosis in patients with optic neuritis as a first demyelination event. (22465890)
2012
15
Brachial neuritis with phrenic nerve involvement. (22721897)
2012
16
Notes on the use of HBO2 with optic neuritis. (22292262)
2011
17
Vestibular neuritis has selective effects on air- and bone-conducted cervical and ocular vestibular evoked myogenic potentials. (21239223)
2011
18
Facial paralysis and lymphocytic facial neuritis in a rhesus macaque (Macaca mulatta) positive for simian retrovirus type D2. (22330582)
2011
19
Acute anterior uveitis and optic neuritis as ocular complications of influenza A infection in an 11-year-old boy. (21732577)
2011
20
Assessment of outcome predictors after first attack of optic neuritis. (22030428)
2011
21
Brachial neuritis masquerading as acute coronary syndrome. (20838916)
2011
22
Ocular vestibular-evoked myogenic potentials to bone-conducted vibration in superior vestibular neuritis show utricular function. (20647134)
2010
23
Diagnostic validity of optic disc and retinal nerve fiber layer evaluations in detecting structural changes after optic neuritis. (20381872)
2010
24
Retinitis and optic neuritis in a child with chickenpox: case report and review of literature. (20622712)
2010
25
Ethambutol-induced optic neuritis and multiple sclerosis: is there an association? (20843609)
2010
26
A case of secondary syphilis presenting as optic neuritis. (20182899)
2010
27
MS-275, an histone deacetylase inhibitor, reduces the inflammatory reaction in rat experimental autoimmune neuritis. (20451583)
2010
28
Demyelinating optic neuritis in children. (18936195)
2009
29
The optic neuritis treatment trial: a definitive answer and profound impact with unexpected results. (18625952)
2008
30
Clinical course of optic neuritis in patients with relapsing neuromyelitis optica. (18195212)
2008
31
Relapsing inflammatory optic neuritis: is it neuromyelitis optica? (18505981)
2008
32
Optic neuritis and the risk of multiple sclerosis--what can we learn from a brain MRI scan? (18779851)
2008
33
Electrophysiological evidence for heterogeneity of lesions in optic neuritis. (17898277)
2007
34
Microfluorimetry defines early axonal damage in a rat model of optic neuritis: a novel method targeting early CNS autoimmunity. (17719649)
2007
35
Historical perspective and future prospective for retinal nerve fiber loss in optic neuritis and multiple sclerosis. (18049278)
2007
36
Optical coherence tomography in optic neuritis. (17198866)
2007
37
Local phenol injection in the treatment of interdigital neuritis of the foot (Morton's neuroma). (16878772)
2005
38
Differentiating traumatic neuritis from poliomyelitis. (14606778)
2003
39
Chronic inflammatory demyelinating polyradiculoneuropathy with histologically proven optic neuritis. (11484826)
2001
40
Comparative studies on pattern VECP between patients with ischemic optic neuropathy and optic neuritis. (10990041)
2000
41
Malignant otitis externa with optic neuritis. (9624378)
1998
42
The effects of monoamine reuptake inhibiting antidepressants in experimental allergic neuritis. (10975734)
1997
43
Peptide specificity of anti-myelin basic protein antibodies in patients with acute optic neuritis and the HLA system. (7516573)
1994
44
Transforming growth factor beta expression in reactive spinal cord microglia and meningeal inflammatory cells during experimental allergic neuritis. (7505838)
1993
45
Tumor necrosis factor alpha gene polymorphism in multiple sclerosis and optic neuritis. (1969423)
1990
46
Macrophages but not Schwann cells express Ia antigen in experimental autoimmune neuritis. (2375636)
1990
47
Optic neuritis, transverse myelitis, and anti-DNA antibodies nine years after thymectomy for myasthenia gravis. (6610427)
1984
48
Chromophobe adenoma masquerading as corticosteroid-responsive optic neuritis. (4369864)
1974
49
The elimination of non-surgical lesions in brain tumor suspects; pseudo-tumor cerebri, and papilledema without increased intracranial pressure (optic neuritis). (18903109)
1948
50
Ten Cases of Acute Retrobulbar Neuritis. (20772322)
1926

Variations for Neuritis

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Expression for genes affiliated with Neuritis

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neuritis

Search GEO for disease gene expression data for Neuritis.

Pathways for genes affiliated with Neuritis

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Sources:
50PathCards, 55Reactome, 30KEGG, 38NCBI BioSystems Database
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Compounds for genes affiliated with Neuritis

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Sources:
45Novoseek, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB
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Compounds related to Neuritis according to GeneCards/GeneDecks:

(show all 21)
idCompoundScoreTop Affiliating Genes
1sulfatide459.9MPZ, PLP1
22,3-cyclic nucleotide459.7PLP1, MOG, MPZ
3glatiramer acetate45 1110.7MPZ, MOG, PLP1
4silver459.7PLP1, MOG
5acetylcholine45 51 29 24 1113.3MOG, PLP1, LTA
6isoleucine459.3MT-ND6, MT-ND4
7glutamate459.1LTA, PLP1, AQP4, MPZ
8Ubiquinol 8248.9MT-ND2, MT-ND6, MT-ND4
9Sulfide248.9MT-ND2, MT-ND6, MT-ND4
10QH2248.9MT-ND2, MT-ND6, MT-ND4
11Ubiquinone Q2248.9MT-ND4, MT-ND6, MT-ND2
12Ubiquinone Q1248.9MT-ND2, MT-ND6, MT-ND4
13FAD248.8MT-ND2, MT-ND6, MT-ND4
14valine458.8MT-ND2, MT-ND6, MT-ND4
15nad29 249.8MT-ND2, MT-ND6, MT-ND4
16methionine458.7MPZ, MT-ND6, MT-ND2, PLP1
17glucose458.5MOG, MT-ND4, MT-CO3, LTA
18oxygen45 249.4LTA, MT-ND2, MT-ND6, MOG
19lipid458.3MPZ, MOG, MT-ND2, PLP1, LTA
20iron45 249.3MT-ND2, MT-ND6, MT-ND4
21nadh45 24 1110.3MT-ND2, MT-ND6, MT-CO3, MT-ND4

GO Terms for genes affiliated with Neuritis

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16Gene Ontology
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Cellular components related to Neuritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:0432099.7PLP1, MPZ

Products for genes affiliated with Neuritis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neuritis

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet