Aliases & Classifications for Neuritis

MalaCards integrated aliases for Neuritis:

Name: Neuritis 12 52 42 14 69
Peripheral Neuritis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1803
MeSH 42 D009443
NCIt 47 C116381
UMLS 69 C0027813

Summaries for Neuritis

MalaCards based summary : Neuritis, also known as peripheral neuritis, is related to motor peripheral neuropathy and ulcerative colitis, and has symptoms including neuralgia and sciatica. An important gene associated with Neuritis is PMP2 (Peripheral Myelin Protein 2), and among its related pathways/superpathways are Cytokine Signaling in Immune system and PAK Pathway. The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, t cells and testes, and related phenotypes are hematopoietic system and behavior/neurological

Wikipedia : 72 Neuritis (/nʊˈraɪtɪs, -njʊ/) is inflammation of a nerve or the general inflammation of the peripheral... more...

Related Diseases for Neuritis

Diseases related to Neuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 422)
id Related Disease Score Top Affiliating Genes
1 motor peripheral neuropathy 31.3 IFNG IL4 TNF
2 ulcerative colitis 29.9 AQP4 MBP TNF
3 choroiditis 29.9 CCL2 IL1B TNF
4 sinusitis 29.6 CCL2 IL1B TNF
5 hypoxia 29.3 MAG MBP MPZ PMP22
6 tularemia 29.1 IFNG IL4 TNF
7 lymphoma 28.5 IFNG IL1B IL4 TNF
8 systemic lupus erythematosus 28.0 CCL2 CCL5 IFNG IL4 TNF
9 pulmonary tuberculosis 28.0 CCL2 CCL5 CXCL10 IFNG TNF
10 rheumatoid arthritis 27.1 CCL2 CCL5 IFNG IL1B IL4 TNF
11 malaria 26.3 CCL2 CCL5 CXCL10 IFNG IL1B IL4
12 optic neuritis 12.4
13 acute retrobulbar neuritis 12.1
14 brachial plexus neuritis 12.0
15 neuromyelitis optica 11.4
16 vestibular neuronitis 11.3
17 flynn-aird syndrome 11.3
18 parsonage turner syndrome 11.3
19 amyotrophy, hereditary neuralgic 11.3
20 transverse myelitis 11.1
21 labyrinthitis 11.1
22 optic papillitis 11.1
23 optic nerve disease 10.8
24 radiation induced brachial plexopathy 10.7
25 amyotrophic neuralgia 10.7
26 autoimmune polyglandular syndrome type 3 10.7 IFNG TNF
27 hereditary proximal myopathy with early respiratory failure 10.7 MPZ PMP22
28 conotruncal heart malformations 10.7 MPZ PMP22
29 hemiplegia alterans 10.7 MPZ PMP22
30 cogan-reese syndrome 10.7 AQP4 MBP
31 mosaic trisomy 1 10.7 IFNG TNF
32 tabatznik syndrome 10.6 IL1B TNF
33 primary systemic mycosis 10.6 IFNG TNF
34 charcot-marie-tooth neuropathy type 4j 10.6 MPZ PMP22
35 tricho onychic dysplasia 10.6 AQP4 MBP TNF
36 submandibular gland disease 10.6 MAG TNF
37 pulmonary hypertension 10.6 IL1B TNF
38 congestive heart failure 10.6 MBP MPZ PMP22
39 mental retardation, x-linked, syndromic 34 10.6 MPZ PMP22
40 proximal symphalangism 10.6 MBP MOG TNF
41 neuropathy, recurrent, with pressure palsies 10.5 MBP MPZ PMP22
42 mixed cell adenoma 10.5 AQP4 MBP MOG
43 niemann-pick disease, type b 10.5 MAG MBP MPZ
44 newborn respiratory distress syndrome 10.5 AQP4 MBP MOG
45 acute necrotizing encephalitis 10.5 IFNG MPZ PMP22
46 hypersplenism 10.5 AQP4 MAG MBP
47 walker dyson syndrome 10.5 IL1B TNF
48 sternal cleft 10.5 IFNG IL1B TNF
49 smarca4-deficient sarcoma of thorax 10.5 CCL5 TNF
50 amyotrophic lateral sclerosis type 10 10.5 IFNG IL1B TNF

Graphical network of the top 20 diseases related to Neuritis:



Diseases related to Neuritis

Symptoms & Phenotypes for Neuritis

UMLS symptoms related to Neuritis:


neuralgia, sciatica

MGI Mouse Phenotypes related to Neuritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10 AQP4 CCL5 CXCL10 IFNG IL1B IL4
2 behavior/neurological MP:0005386 9.97 AQP4 IFNG MAG MBP MOG MPZ
3 immune system MP:0005387 9.93 AQP4 CCL2 CCL5 CXCL10 IFNG IL1B
4 nervous system MP:0003631 9.73 CXCL10 IFNG IL1B IL4 MAG MBP
5 vision/eye MP:0005391 9.17 TNF AQP4 IFNG IL4 MBP MOG

Drugs & Therapeutics for Neuritis

Drugs for Neuritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 167)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
3
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2 53-03-2 5865
4
Glatiramer Acetate Approved, Investigational Phase 4,Phase 3,Phase 2 147245-92-9 3081884
5
Mitoxantrone Approved, Investigational Phase 4 65271-80-9 4212
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 1,Phase 2,Early Phase 1 50-02-2 5743
7
Interferon beta-1a Approved, Investigational Phase 4,Phase 3 145258-61-3 6438354
8
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
9
Clofazimine Approved, Investigational Phase 4 2030-63-9 2794
10
Dapsone Approved, Investigational Phase 4 80-08-0 2955
11
Rifampin Approved Phase 4 13292-46-1 5458213 5381226
12
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
13
Mannitol Approved, Investigational Phase 4 69-65-8 453 6251
14
Nitric Oxide Approved Phase 4 10102-43-9 145068
15
Prilocaine Approved Phase 4 721-50-6 4906
16 Racepinephrine Approved Phase 4
17
Acetylcholine Approved Phase 4 51-84-3 187
18
Mycophenolate mofetil Approved, Investigational Phase 4 128794-94-5 5281078
19
Mycophenolic acid Approved Phase 4 24280-93-1 446541
20
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 59-30-3 6037
21
leucovorin Approved, Nutraceutical Phase 4 58-05-9 143 6006
22 Adrenocorticotropic Hormone Phase 4,Early Phase 1
23 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
24 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
25 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2,Phase 1
26 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
27 beta-endorphin Phase 4,Early Phase 1
28 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
29 glucocorticoids Phase 4,Phase 3,Phase 2,Phase 1
30 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
31 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
33 Melanocyte-Stimulating Hormones Phase 4,Early Phase 1
34 Methylprednisolone acetate Phase 4,Phase 3,Phase 2,Phase 1
35 Methylprednisolone Hemisuccinate Phase 4,Phase 3,Phase 2,Phase 1
36 Neuroprotective Agents Phase 4,Phase 3,Phase 2,Phase 1
37 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
38 Prednisolone acetate Phase 4,Phase 3,Phase 2,Phase 1
39 Prednisolone hemisuccinate Phase 4,Phase 3,Phase 2,Phase 1
40 Prednisolone phosphate Phase 4,Phase 3,Phase 2,Phase 1
41 Protective Agents Phase 4,Phase 3,Phase 2,Phase 1
42 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2
43 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
44 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1
45 Analgesics Phase 4,Phase 2,Phase 3
46 Topoisomerase Inhibitors Phase 4
47 BB 1101 Phase 4,Phase 1,Phase 2,Early Phase 1
48 Dexamethasone acetate Phase 4,Phase 1,Phase 2,Early Phase 1 1177-87-3
49 HIV Protease Inhibitors Phase 4,Phase 2,Phase 1
50
protease inhibitors Phase 4,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 122)

id Name Status NCT ID Phase Drugs
1 A Phase IV Trial of Neuroprotection With ACTH in Acute Optic Neuritis Unknown status NCT01838174 Phase 4 ACTHAR Gel (ACTH);IV steroids with oral taper
2 Optical Coherence Tomography: Glatiramer in Clinically Isolated Syndrome or Early Relapsing Remitting Multiple Sclerosis (MS) Unknown status NCT00910598 Phase 4 glatiramer acetate
3 Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders Unknown status NCT02021825 Phase 4 Mitoxantrone
4 Effect of High-Dose Prednisolone (Solu Dacortin®) Treatment on Choroidal and Optic Nerve Head Blood Flow in Humans Completed NCT00312325 Phase 4 Prednisolone
5 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4 interferon beta 1a 30 ug IM once weekly
6 Oral Corticotherapy in Megadoses to Treat Multiple Sclerosis During Relapse Completed NCT00753792 Phase 4 methylprednisolone;methylprednisolone;Placebo
7 Dexamethasone & Bupivacaine vs Bupivacaine Alone in Combined Femoral and Sciatic Nerve Block for Perioperative Analgesia in Patients Undergoing Lower Limb Surgeries Completed NCT02576782 Phase 4 Perineural Dexamethasone and bupivacaine;Systemic Dexamethasone plus perineural bupivacaine;intravenous saline plus perineural bupivacaine
8 Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age Completed NCT01985997 Phase 4
9 Uniform Multidrug Therapy Regimen for Leprosy Patients Completed NCT00669643 Phase 4 PB 6 doses - Rifampicin and Dapsone;PB 6 doses - Rifampicin, Clofazimine and Dapsone;MB 12 doses - Rifampicin, Clofazimine and Dapsone;MB 6 doses - Rifampicin, Clofazimine and Dapsone
10 Evaluation of Ureteral Patency in the Post-indigo Carmine Era Completed NCT02677623 Phase 4 Pyridium;Sodium Fluorescein;Mannitol
11 Study to Evaluate the Efficacy of Botulinum Toxin Serotype A Injections for Cervicobrachial Myofascial Syndrome Completed NCT00241215 Phase 4 Botulinum toxin serotype A
12 A Pilot Study of Mitoxantrone for the Treatment of Recurrent Neuromyelitis Optica (Devic’s Disease) Completed NCT00304291 Phase 4 Mitoxantrone
13 Post-lesion Administration of Dexamethasone to Prevent the Development of Neuritis After Radiofrequency Ablation Recruiting NCT03247413 Phase 4 Dexamethasone 4 mg/ml;Normal saline
14 Mycophenolate Mofetil Treatment With Neuromyelitis Optica Spectrum Disorders in Chinese Patients Enrolling by invitation NCT02809079 Phase 4 Mycophenolate mofetil;Prednisone
15 Modeling and Treating the Pathophysiology of Demyelination in Multiple Sclerosis Terminated NCT00854750 Phase 4 ACTHAR;ACTHAR;ACTHAR;ACTHAR
16 Induction Therapy With a Single High Dose Bolus of Intravenous Methotrexate With Leucovorin Rescue, Prior to Initiation of AVONEX® Treatment, in Patients Presenting With a First Acute Demyelinating Event. Withdrawn NCT00037115 Phase 4 interferon beta 1a;methotrexate;methylprednisolone
17 A Proof-of-Concept Study to Correlate Retinal Nerve Fiber Layer Changes in Patients With Multiple Sclerosis Treated With Natalizumab or Interferon Beta 1-a Withdrawn NCT00771043 Phase 4 TYSABRI and AVONEX
18 The Efficacy of Steroid Therapy in Vestibular Neuritis Unknown status NCT02098330 Phase 3 Ginkgo biloba & Methylprednisolone;Ginkgo biloba
19 Simvastatin Treatment of Patients With Acute Optic Neuritis Unknown status NCT00261326 Phase 3 simvastatin;placebo
20 Optic Neuritis Treatment Trial (ONTT) Unknown status NCT00000146 Phase 3 Methylprednisolone;Prednisone
21 Phase III Randomized, Double-Blind, Sham-Controlled Study of Plasma Exchange for Acute Severe Attacks of Inflammatory Demyelinating Disease Refractory to Intravenous Methylprednisolone Unknown status NCT00004645 Phase 3
22 Optic Neuritis Recovery After Oral or IV Corticosteroids Completed NCT01524250 Phase 2, Phase 3 corticosteroids;corticosteroids
23 A Randomized, Double-blind, Placebo-controlled, Multicenter Study of the Effects of Glatiramer Acetate (GA) on the Retinal Nerve Fiber Layer (RNFL) and Visual Function in Patients With a First Episode of Acute Optic Neuritis (AON). (Octagon) Completed NCT00856635 Phase 3 Glatiramer Acetate;placebo
24 Ampyra for Optic Neuritis in MS Completed NCT01337986 Phase 2, Phase 3 Dalfampridine/Placebo;Placebo/Dalfampridine
25 Intravenous Immunoglobulin Therapy in Optic Neuritis Completed NCT00000117 Phase 3 Immunoglobulin
26 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
27 Study of the Effectiveness of Intravenous Immune Globulin (10%) for the Treatment of Multifocal Motor Neuropathy Completed NCT00666263 Phase 3
28 Hypoalgesic Effect of Neural Mobilization Versus Ibuprofen Pharmacologic Treatment Completed NCT02593721 Phase 2, Phase 3 Ibuprofen
29 Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Multifocal Motor Neuropathy. Completed NCT01827072 Phase 3 NPB-01
30 Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients Completed NCT03002038 Phase 2, Phase 3 Azathioprine;Rituximab
31 Erythropoietin in Methanol Associated Optic Neuropathy: A Phase-2 Clinical Trial (EPO-MAON Study) Recruiting NCT02376881 Phase 3 Erythropoietin
32 Efficacy and Safety Study as Add-on Therapy of SA237 to Treat NMO and NMOSD Recruiting NCT02028884 Phase 3 SA237;Placebo
33 A Double-masked, Placebo-controlled Study With Open Label Period to Evaluate MEDI-551 in Neuromyelitis Optica and Neuromyelitis Optica Spectrum Disorders Recruiting NCT02200770 Phase 2, Phase 3
34 Treatment of Optic Neuritis With Erythropoietin: a Randomised, Double-blind, Placebo-controlled Trial Active, not recruiting NCT01962571 Phase 3 Erythropoietin alfa;Placebo
35 Effect of MD1003 in Chronic Visual Loss Related to Optic Neuritis in Multiple Sclerosis Active, not recruiting NCT02220244 Phase 3 MD1003 100mg capsule
36 A Double Blind Trial To Evaluate The Safety And Efficacy Of Eculizumab In Relapsing NMO Patients (PREVENT Study) Active, not recruiting NCT01892345 Phase 3 Eculizumab
37 Efficacy and Safety Study as Monotherapy of SA237 to Treat NMO and NMOSD Active, not recruiting NCT02073279 Phase 3 SA237;Placebo
38 An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients Enrolling by invitation NCT02003144 Phase 3
39 MOdification of VIsual Outcomes After Optic Neuritis in CIS or MS by Gilenya (MOVING Study) Terminated NCT01647880 Phase 2, Phase 3 Verum arm receiving Gilenya®;Active Comparator receiving Extavia®
40 A Multicentre randomiSed Controlled TRial of IntraVEnous Immunoglobulin Versus Standard Therapy for Transverse Myelitis Terminated NCT02398994 Phase 3 Intravenous Methylprednisolone;Intravenous Immunoglobulin
41 Using Optical Coherence Tomography (OCT) to Evaluate the Efficacy and Safety of PEGylated Interferon Beta-1a (BIIB017) in Patients With Relapsing Multiple Sclerosis Withdrawn NCT01337427 Phase 3 BIIB017
42 Effect of Vitamin D on Retinal Changes in Patient With Optic Neuritis by Optic Coherence Tomography Unknown status NCT01465893 Phase 2 Vitamin D;Vitamin D withheld
43 Amiloride Clinical Trial In Optic Neuritis Unknown status NCT01802489 Phase 2 Amiloride;Placebo
44 Amiloride Hydrochlorothiazide as Treatment of Acute Inflammation of the Optic Nerve Unknown status NCT01879527 Phase 2 Amiloride hydrochlorothiazide;Sugar pill
45 Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Progressive Multiple Sclerosis and Neuromyelitis Optica Unknown status NCT01364246 Phase 1, Phase 2
46 AIMSPRO in the Treatment of Bladder Dysfunction in Secondary Progressive Multiple Sclerosis Unknown status NCT01228396 Phase 2 Hyperimmune caprine serum against HIV lysate
47 Autologous Mesenchymal Stem Cells for the Treatment of Neuromyelitis Optica Spectrum Disorders Unknown status NCT02249676 Phase 2
48 BIIB033 In Acute Optic Neuritis (AON) Completed NCT01721161 Phase 2 Placebo
49 Safety and Efficacy Study of Erythropoietin as add-on Therapy of Methylprednisolone to Treat Acute Optic Neuritis Completed NCT00355095 Phase 2 Erythropoietin
50 Neuroprotection With Phenytoin in Optic Neuritis Completed NCT01451593 Phase 2 Phenytoin;Placebo

Search NIH Clinical Center for Neuritis

Cochrane evidence based reviews: neuritis

Genetic Tests for Neuritis

Anatomical Context for Neuritis

MalaCards organs/tissues related to Neuritis:

39
Eye, T Cells, Testes, Brain, Bone, Pituitary, Spinal Cord

Publications for Neuritis

Articles related to Neuritis:

(show top 50) (show all 1086)
id Title Authors Year
1
Transorbital Sonography and Visual Outcome for the Diagnosis and Monitoring of Optic Neuritis. ( 27862614 )
2017
2
Pediatric Optic Neuritis. ( 28941527 )
2017
3
Cortical blindness and not optic neuritis as a cause of vision loss in a SjAPgren's syndrome (SS) patient with the neuromyelitis optica spectrum disorder (NMOSD): Challenges of ascribing demyelinating syndromes to SS: a case report. ( 28834867 )
2017
4
Perioptic neuritis related with varicella-zoster virus infection preceding sixth cranial nerve palsy and progressive outer retinal necrosis in a immunocompetent patient. ( 28131177 )
2017
5
Optic neuritis in a patient with celiac disease. ( 28803640 )
2017
6
Vascular hypoperfusion in acute optic neuritis is a potentially new neurovascular model for demyelinating diseases. ( 28926646 )
2017
7
Pediatric Optic Neuritis: What Is New. ( 28806345 )
2017
8
A Functional and Neuropathological Testing Paradigm Reveals New Disability-Based Parameters and Histological Features for P0180-190-Induced Experimental Autoimmune Neuritis in C57BL/6 Mice. ( 28082327 )
2017
9
Time is vision in recurrent optic neuritis. ( 28823952 )
2017
10
The Renin-Angiotensin System Regulates Neurodegeneration in a Mouse Model of Optic Neuritis. ( 28919108 )
2017
11
Concurrent intramedullary spinal cord and multiple intracranial tuberculomas with tuberculous optic neuritis: A rare case report. ( 28941861 )
2017
12
Paediatric optic neuritis: factors leading to unfavourable outcome and relapses. ( 28903961 )
2017
13
Neuroprotection and visual function after optic neuritis. ( 27941524 )
2017
14
Optic neuritis in patients with anti-MOG antibodies spectrum disorder: MRI and clinical features from a large multicentric cohort in France. ( 28914353 )
2017
15
Long-term structural retinal changes in patients with optic neuritis related to multiple sclerosis. ( 28860702 )
2017
16
Retinal segmented layers with strong aquaporin-4 expression suffered more injuries in neuromyelitis optica spectrum disorders compared with optic neuritis with aquaporin-4 antibody seronegativity detected by optical coherence tomography. ( 28057643 )
2017
17
Diagnostic accuracy of optical coherence tomography inter-eye percentage difference for optic neuritis in multiple sclerosis. ( 28887838 )
2017
18
Video Head Impulse Test for Early Diagnosis of Vestibular Neuritis Among Acute Vertigo. ( 28862109 )
2017
19
Acute Zonal Occult Outer Retinopathy Associated With Retrobulbar Optic Neuritis. ( 28252457 )
2017
20
Prognostic factors and disease course in aquaporin-4 antibody-positive Chinese patients with acute optic neuritis. ( 28879451 )
2017
21
Bevacizumab for Radiation Induced Optic Neuritis Among Aggressive Residual/Recurrent Suprasellar Tumors: More Than a Mere Antineoplastic Effect. ( 28754639 )
2017
22
Should Oral Corticosteroids Be Used to Treat Demyelinating Optic Neuritis? ( 28857910 )
2017
23
Prevalence and Incidence of Optic Neuritis in Patients with Different Types of Uveitis. ( 28895765 )
2017
24
UNILATERAL OPTIC NEURITIS AND CENTRAL RETINAL VASCULITIS DUE TO OCULAR SYPHILIS. ( 28816862 )
2017
25
No evidence of association between optic neuritis and secondary LHON mtDNA mutations in patients with multiple sclerosis. ( 28802665 )
2017
26
Optic neuritis: the eye as a window to the brain. ( 27906756 )
2017
27
Isolated palatal weakness without optic neuritis as the presenting manifestation of multiple sclerosis and its diagnostic dilemma with acute disseminated encephalomyelitis in a young boy. ( 28469990 )
2017
28
Infant brachial neuritis following a viral prodrome: a case in a 6-month old child and review of the literature. ( 28884231 )
2017
29
Attenuation of experimental autoimmune neuritis with locally administered lovastatin-encapsulating poly(lactic-co-glycolic) acid nanoparticles. ( 27861905 )
2017
30
Insulin Neuritis and Effect of Pregabalin. ( 28827482 )
2017
31
Trans-synaptic degeneration in the optic pathway. A study in clinically isolated syndrome and early relapsing-remitting multiple sclerosis with or without optic neuritis. ( 28850630 )
2017
32
Retinal Nerve Fiber Layer May Be Better Preserved in MOG-IgG versus AQP4-IgG Optic Neuritis: A Cohort Study. ( 28125740 )
2017
33
Myelin-oligodendrocyte-glycoprotein (MOG) autoantibodies as potential markers of severe optic neuritis and subclinical retinal axonal degeneration. ( 27844165 )
2017
34
Postinfectious Anti-Myelin Oligodendrocyte Glycoprotein Antibody Positive Optic Neuritis and Myelitis. ( 28820014 )
2017
35
Diagnosis and Treatment of Vestibular Neuritis/Neuronitis or Peripheral Vestibulopathy (PVP)? Open Questions and Possible Answers. ( 28346294 )
2017
36
20/40 or Better Visual Acuity After Optic Neuritis: Not as Good as We Once Thought? ( 27472185 )
2016
37
Quantitative visual tests after poorly recovered optic neuritis due to multiple sclerosis. ( 27919490 )
2016
38
High sensitivity of diffusion tensor imaging in discriminating idiopathic demyelinating optic neuritis. ( 27500122 )
2016
39
Serum sPECAM-1 and sVCAM-1 levels are associated with conversion to multiple sclerosis in patients with optic neuritis. ( 27806869 )
2016
40
Vestibular neuritis: Involvement and long-term recovery of individual semicircular canals. ( 27545414 )
2016
41
Recurrent optic neuritis and neuromyelitis optica-IgG following first and second human papillomavirus vaccinations. ( 27046292 )
2016
42
Retinal ganglion cell and axonal loss in optic neuritis: risk factors and visual functions. ( 27858936 )
2016
43
Optic neuritis with secondary retinal venous stasis in a case of abdominal tuberculosis. ( 27843238 )
2016
44
Case-centered Analysis of Optic Neuritis After Vaccines. ( 27069066 )
2016
45
Insulin neuritis or treatment-induced diabetic neuropathy of diabetes. ( 27474367 )
2016
46
Retinal nerve fiber layer thickness by Stratus and Cirrus OCT in retrobulbar optic neuritis and nonarteritic ischemic optic neuropathy. ( 27312208 )
2016
47
Acute optic neuritis with diffusion restriction on MRI. ( 27655875 )
2016
48
Optic neuritis with TNF alpha antagonists. ( 27213191 )
2016
49
Pseudo-subarachnoid hemorrhage and optic neuritis in an 18-year-old girl with sodium valproate overdose. ( 27904589 )
2016
50
Optic neuritis as a phase 2 paradigm for neuroprotection therapies of multiple sclerosis: update on current trials and perspectives. ( 27035900 )
2016

Variations for Neuritis

Expression for Neuritis

Search GEO for disease gene expression data for Neuritis.

Pathways for Neuritis

Pathways related to Neuritis according to GeneCards Suite gene sharing:

(show all 47)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.29 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2
Show member pathways
13.23 CCL2 CCL5 CXCL10 IL1B IL4 TNF
3
Show member pathways
12.82 CCL2 CCL5 CXCL10 IFNG IL1B TNF
4
Show member pathways
12.73 CCL2 CCL5 CXCL10 IFNG IL1B IL4
5
Show member pathways
12.67 CCL5 CXCL10 IFNG IL1B TNF
6
Show member pathways
12.54 IFNG IL1B IL4 TNF
7
Show member pathways
12.53 CCL2 IFNG IL1B TNF
8
Show member pathways
12.37 IFNG IL1B IL4 TNF
9 12.3 CCL2 CCL5 CXCL10 IFNG IL1B IL4
10
Show member pathways
12.21 CCL2 CXCL10 IFNG IL1B IL4 TNF
11
Show member pathways
12.2 IFNG IL1B IL4 TNF
12
Show member pathways
12.15 CXCL10 IFNG IL1B IL4 TNF
13
Show member pathways
12.1 IFNG IL1B IL4 TNF
14 12.05 CCL2 IFNG IL1B TNF
15 11.98 IFNG IL1B TNF
16
Show member pathways
11.96 CCL2 CCL5 CXCL10
17 11.94 CCL2 IL1B IL4 TNF
18 11.93 IFNG IL4 TNF
19
Show member pathways
11.91 IFNG IL1B IL4
20 11.91 CCL2 CCL5 CXCL10 IL1B TNF
21
Show member pathways
11.89 IFNG IL1B TNF
22 11.86 MBP MPZ PMP22
23 11.85 CCL2 IL1B TNF
24
Show member pathways
11.85 IFNG IL1B IL4
25 11.84 IL1B IL4 TNF
26 11.83 IFNG IL1B TNF
27 11.76 IFNG IL1B IL4 TNF
28 11.72 CCL2 CCL5 IFNG IL1B TNF
29
Show member pathways
11.71 IFNG IL4 TNF
30 11.71 IFNG IL1B TNF
31
Show member pathways
11.62 IFNG IL1B TNF
32 11.52 CCL2 IFNG IL1B TNF
33 11.49 CCL2 IFNG IL1B TNF
34 11.48 IFNG IL1B TNF
35 11.45 IFNG IL1B TNF
36 11.36 CXCL10 IFNG IL1B
37 11.36 AQP4 CCL2 CXCL10 IFNG IL1B IL4
38 11.35 CCL2 CCL5 IL1B IL4 TNF
39 11.32 IFNG IL1B TNF
40 11.26 IFNG IL1B IL4 TNF
41 11.21 IFNG IL1B IL4 TNF
42 11.15 CCL2 IFNG IL1B
43 11.12 CCL2 CCL5 CXCL10 IL1B IL4 TNF
44 11.03 CCL2 CCL5 CXCL10 IL1B IL4 TNF
45 10.93 CCL2 IL1B TNF
46 10.84 IL1B IL4
47 10.55 MAG MBP

GO Terms for Neuritis

Cellular components related to Neuritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.8 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2 myelin sheath GO:0043209 9.46 MAG MBP MPZ PMP2
3 external side of plasma membrane GO:0009897 9.35 AQP4 CXCL10 IFNG IL4 TNF
4 compact myelin GO:0043218 8.62 MAG PMP22

Biological processes related to Neuritis according to GeneCards Suite gene sharing:

(show all 44)
id Name GO ID Score Top Affiliating Genes
1 MAPK cascade GO:0000165 9.92 CCL2 CCL5 IL1B MBP TNF
2 positive regulation of protein phosphorylation GO:0001934 9.88 IFNG IL1B IL4 TNF
3 response to ethanol GO:0045471 9.87 CCL2 IL4 MT-ND4
4 chemotaxis GO:0006935 9.87 CCL2 CCL5 CXCL10 IL4
5 positive regulation of sequence-specific DNA binding transcription factor activity GO:0051091 9.86 IL1B IL4 TNF
6 cellular response to lipopolysaccharide GO:0071222 9.86 CCL2 CXCL10 IFNG TNF
7 response to virus GO:0009615 9.84 CCL5 CXCL10 IFNG TNF
8 chemokine-mediated signaling pathway GO:0070098 9.83 CCL2 CCL5 CXCL10
9 cell chemotaxis GO:0060326 9.82 CCL2 CCL5 CXCL10
10 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.81 CCL5 IFNG IL4
11 cellular response to interferon-gamma GO:0071346 9.8 AQP4 CCL2 CCL5
12 humoral immune response GO:0006959 9.8 CCL2 IFNG TNF
13 myelination GO:0042552 9.79 MBP MPZ PMP22
14 cellular response to organic cyclic compound GO:0071407 9.78 CCL2 CCL5 IL1B TNF
15 positive regulation of nitric oxide biosynthetic process GO:0045429 9.76 IFNG IL1B TNF
16 regulation of insulin secretion GO:0050796 9.76 CCL5 IFNG IL1B TNF
17 neutrophil chemotaxis GO:0030593 9.73 CCL2 CCL5 IFNG IL1B
18 positive regulation of T cell proliferation GO:0042102 9.71 CCL5 IFNG IL1B IL4
19 negative regulation of lipid catabolic process GO:0050995 9.69 IL1B TNF
20 negative regulation of growth of symbiont in host GO:0044130 9.69 IFNG TNF
21 positive regulation of monocyte chemotaxis GO:0090026 9.69 CCL2 CCL5 CXCL10
22 positive regulation of T cell migration GO:2000406 9.68 CCL5 CXCL10
23 positive regulation of macrophage chemotaxis GO:0010759 9.68 CCL2 CCL5
24 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.68 IL1B TNF
25 macrophage chemotaxis GO:0048246 9.67 CCL2 CCL5
26 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.67 IL1B TNF
27 cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742 9.67 MAG MPZ
28 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.67 IFNG IL1B TNF
29 positive regulation of cell adhesion GO:0045785 9.67 CCL2 CCL5 IFNG TNF
30 positive regulation of isotype switching to IgG isotypes GO:0048304 9.66 IFNG IL4
31 regulation of defense response to virus by host GO:0050691 9.66 IFNG IL1B
32 positive regulation of interleukin-6 biosynthetic process GO:0045410 9.65 IFNG IL1B
33 positive regulation of MHC class II biosynthetic process GO:0045348 9.65 IFNG IL4
34 regulation of establishment of endothelial barrier GO:1903140 9.63 IL1B TNF
35 positive regulation of fever generation GO:0031622 9.62 IL1B TNF
36 protein kinase B signaling GO:0043491 9.62 CCL2 CCL5 IL1B TNF
37 sequestering of triglyceride GO:0030730 9.6 IL1B TNF
38 positive regulation of mononuclear cell migration GO:0071677 9.59 IL4 TNF
39 lipopolysaccharide-mediated signaling pathway GO:0031663 9.56 CCL2 CCL5 IL1B TNF
40 immune response GO:0006955 9.56 CCL2 CCL5 CXCL10 IFNG IL1B IL4
41 positive regulation of vitamin D biosynthetic process GO:0060557 9.55 IFNG TNF
42 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.33 IFNG IL1B TNF
43 positive regulation of chemokine biosynthetic process GO:0045080 8.92 IFNG IL1B IL4 TNF
44 inflammatory response GO:0006954 10 CCL2 CCL5 CXCL10 IL1B TNF

Molecular functions related to Neuritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL2 CCL5 CXCL10 IFNG IL1B IL4
2 chemokine activity GO:0008009 9.13 CCL2 CCL5 CXCL10

Sources for Neuritis

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