MCID: NRT004
MIFTS: 46

Neuritis malady

Summaries for Neuritis

Sources:
64Wikipedia, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Peripheral neuropathy (PN) is damage or disease affecting nerves, which may affect sensation, movement,... more...

MalaCards: Neuritis, also known as peripheral neuritis, is related to neuromyelitis optica and myelitis. An important gene associated with Neuritis is SEPT9 (septin 9), and among its related pathways are Spinal Cord Injury and Glial Cell Differentiation. The compounds glatiramer acetate and 2,3-cyclic nucleotide have been mentioned in the context of this disorder. Related mouse phenotypes are nervous system and vision/eye.

Aliases & Classifications for Neuritis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH
See all sources

Aliases & Descriptions:

neuritis 8 10 45 61
peripheral neuritis 8


External Ids:

Disease Ontology8 DOID:1803
MeSH35 D009443

Related Diseases for Neuritis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Neuritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 228)
idRelated DiseaseScoreTop Affiliating Genes
1neuromyelitis optica30.8MOG, MBP, AQP4
2myelitis30.5AQP4, MBP
3transverse myelitis30.4AQP4, MBP
4acute disseminated encephalomyelitis30.3MOG, MBP, AQP4
5uveitis30.3CXCL11, RCVRN, LTA
6tuberculosis30.0MBP
7relapsing-remitting multiple sclerosis30.0MBP, MOG
8leber hereditary optic neuropathy29.9MT-ND2, MT-CO3, MT-ND6, MT-ND1, MT-ND5, MT-ND4
9tetanus29.7LTA, PLP1, MPZ, MBP, MOG
10brachial plexus neuropathy29.7MPZ
11wallerian degeneration29.7MPZ, MAG
12adenocarcinoma29.7AQP4
13n syndrome10.7
14brachial plexus neuritis10.5
15acute retrobulbar neuritis10.5
16ischemic neuropathy10.4
17ischemic optic neuropathy10.4
18hereditary neuralgic amyotrophy10.4
19parsonage turner syndrome10.4
20guillain-barr� syndrome10.3
21systemic lupus erythematosus10.3
22herpes zoster10.3
23turner syndrome10.3
24herpes zoster ophthalmicus10.3
25optic neuropathy, anterior ischemic10.2
26measles10.2
27scotoma10.1
28borderline leprosy10.1
29chickenpox10.1
30hepatitis a10.1
31vestibular disease10.1
32pediatric multiple sclerosis10.1
33neurosyphilis10.1
34nonarteritic anterior ischemic optic neuropathy10.1
35hepatitis c10.0
36choroiditis10.0
37meningoencephalitis10.0
38vestibular nystagmus10.0
39adenoma10.0
40vasculitis10.0
41allergic encephalomyelitis10.0
42chronic pain10.0
43sinusitis10.0
44leukodystrophy10.0PLP1
45neuropathy10.0MBP, MPZ, MAG
46lactic acidosis10.0MT-ND5
47opa3-related 3-methylglutaconic aciduria10.0MT-ND4
48dementia10.0TPPP3, PLP1
49myopathy10.0MPZ
50blindness10.0RCVRN, MT-ND4

Graphical network of the top 20 diseases related to Neuritis:



Diseases related to neuritis

Clinical Features for Neuritis

Drugs & Therapeutics for Neuritis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Neuritis

Drug clinical trials:

Search ClinicalTrials for Neuritis

Search NIH Clinical Center for Neuritis

Search CenterWatch for Neuritis

Genetic Tests for Neuritis

Anatomical Context for Neuritis

Animal Models for Neuritis or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Neuritis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000363110.3AQP4, MOG, MBP, MPZ, GHRH, MT-ND6
2MP:000539110.2MOG, MBP, MT-ND6, LTA, RCVRN, PLP1
3MP:000538710.0AQP4, MOG, PLP1, LTA, SOD3, MT-ND2

Publications for Neuritis

Sources:
51PubMed
See all sources

Articles related to Neuritis:

(show top 50)    (show all 888)
idTitleAuthorsYear
1
Differential diagnoses to MS: experiences from an optic neuritis clinic. (24158275)
2014
2
Blood plasma levels of microelements in patients with history of optic neuritis. (24083481)
2014
3
Berberine Ameliorates Experimental Autoimmune Neuritis by Suppressing both Cellular and Humoral Immunity. (24354407)
2014
4
Acute disseminated encephalomyelitis without optic neuritis followed by optic neuritis in a child due to the sudden cessation of steroid therapy. (24171829)
2014
5
Chrysin Attenuates Experimental Autoimmune Neuritis by Suppressing Immuno-inflammatory Responses. (24412705)
2014
6
A case of optic neuritis incidentally detected by somatostatin receptor scintigraphy. (24094374)
2013
7
Clinical and pathological features of acute optic neuritis in Chinese patients. (23652052)
2013
8
Relationship between cerebrospinal fluid biomarkers for inflammation, demyelination and neurodegeneration in acute optic neuritis. (24116216)
2013
9
Calcium influx and calpain activation mediate preclinical retinal neurodegeneration in autoimmune optic neuritis. (23860028)
2013
10
Subretinal angiostrongyliasis-induced optic neuritis. (23818750)
2013
11
Optic neuritis combined with hepatitis B and neurosyphilis. (24034115)
2013
12
Pituitary apoplexy presented with optic neuritis. (24250918)
2013
13
Brachial neuritis with phrenic nerve involvement. (22721897)
2012
14
Forced-exercise attenuates experimental autoimmune neuritis. (22569066)
2012
15
Atypical forms of optic neuritis. (22981300)
2012
16
Sphenoid sinus carcinoma mimicking retrobulbar optic neuritis. (22352827)
2012
17
Disc swelling and mild initial visual acuity loss predict a better short-term visual acuity outcome in bilateral acute optic neuritis. (22819060)
2012
18
Optical coherence tomography segmentation reveals ganglion cell layer pathology after optic neuritis. (22006982)
2012
19
Difference in the nature of dizziness between vestibular neuritis and sudden sensorineural hearing loss with vertigo. (22569141)
2012
20
Correlating the head shake-sensory organizing test with dizziness handicap inventory in compensation after vestibular neuritis. (22215455)
2012
21
Outcomes of toll-like receptors' antagonism in steroid-resistant optic neuritis; a pilot study. (22169982)
2012
22
Human vision with a lesion of the parvocellular pathway: an optic neuritis model for selective contrast sensitivity deficits with severe loss of midget ganglion cell function. (22006271)
2011
23
Charcot-Marie-Tooth disease associated with recurrent optic neuritis. (21764587)
2011
24
Typical brachial neuritis (Parsonage-Turner syndrome) with hourglass-like constrictions in the affected nerves. (21601996)
2011
25
Early factors associated with axonal loss after optic neuritis. (22190367)
2011
26
Acute optic neuritis following infection with chikungunya virus in southern rural India. (21131222)
2011
27
Generalized serpiginous eruption during immunosuppressive treatment for leprosy reactive neuritis. (22216360)
2011
28
Corticosteroids in the treatment of vestibular neuritis: a systematic review and meta-analysis. (20009780)
2010
29
Visual field profile of optic neuritis: a final follow-up report from the optic neuritis treatment trial from baseline through 15 years. (20212204)
2010
30
Interrelationship of optical coherence tomography and multifocal visual-evoked potentials after optic neuritis. (20042660)
2010
31
Brain MRI lesions characteristic of neuromyelitis optica and positive anti-aquaporin 4-antibody may predict longitudinal extensive myelitis and optic neuritis in SjAPgren's syndrome. (20558506)
2010
32
Anti-aquaporin-4 antibody-positive optic neuritis treated with double-filtration plasmapheresis. (20698801)
2010
33
Measurement of retinal nerve fiber layer thickness in optic atrophy eyes of patients with optic neuritis using optical coherence tomography. (20191363)
2010
34
Neural fractalkine expression is closely linked to pain and pancreatic neuritis in human chronic pancreatitis. (19153557)
2009
35
Retrobulbar optic neuritis after Hepatitis A vaccination in a HIV-infected patient. (19730450)
2009
36
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis. (19670438)
2009
37
Systemic lupus erythematosus-associated optic neuritis: clinical experience and literature review. (18507726)
2009
38
Bilateral optic neuritis as initial manifestation of neurosyphilis in a HIV-positive patient. (18949905)
2008
39
Optic neuritis caused by intraocular angiostrongyliasis. (19062688)
2008
40
Correlation between full-field and multifocal VEPs in optic neuritis. (17680288)
2008
41
Apo E in multiple sclerosis and optic neuritis: the apo E-epsilon4 allele is associated with progression of multiple sclerosis. (16193886)
2005
42
Immunogenetics of optic neuritis in children with multiple sclerosis]. (12506649)
2002
43
Use of magnetic resonance imaging to differentiate optic neuritis and nonarteritic anterior ischemic optic neuropathy. (12208717)
2002
44
Augmented expression of tumour necrosis factor-alpha and lymphotoxin in mononuclear cells in multiple sclerosis and optic neuritis. (8624683)
1996
45
Bilateral retrobulbar neuritis following unilateral herpes zoster ophthalmicus. (8183526)
1994
46
A case of hypertrophic interstitial neuritis coexisting with dementia and cerebellar degeneration. (5319475)
1965
47
GAS GANGRENE INFECTION, ANTITOXIN, AND SERUM NEURITIS. (14331998)
1965
48
Epidemiologic study of a brachial plexus neuritis outbreak in northeast Czechoslovakia. (13864958)
1961
49
Ten Cases of Acute Retrobulbar Neuritis. (20772322)
1926
50
Report of Two Unusual Complications of Herpes Zoster Ophthalmicus: (a) Acute Retrobulbar Neuritis (Neuritis Axialis); (b) Acute Glaucoma. (16692478)
1919

Genetic Variations for Neuritis

Expression for genes affiliated with Neuritis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Neuritis

Search GEO for disease gene expression data for Neuritis.

Pathways for genes affiliated with Neuritis

Sources:
38NCBI BioSystems Database, 54Reactome, 30KEGG
See all sources

Compounds for genes affiliated with Neuritis

Sources:
45Novoseek, 11DrugBank, 24HMDB, 29IUPHAR, 50PharmGKB, 60Tocris Bioscience
See all sources

Compounds related to Neuritis according to GeneCards/GeneDecks:

(show all 31)
idCompoundScoreTop Affiliating Genes
1glatiramer acetate45 1111.8MPZ, PLP1, MBP, MOG
22,3-cyclic nucleotide4510.8PLP1, MAG, MPZ, MBP, MOG
3sulfatide4510.8MPZ, PLP1, MBP, MAG
4cerebrosides4510.8MBP, MPZ
5valine4510.7MT-ND2, MT-ND5, MT-ND4, MT-ND1, MT-ND6
6methionine4510.7SOD3, MPZ, PLP1, MT-ND5, MT-ND6, MT-ND1
7nadh45 11 2412.7MT-CO3, MT-ND5, MT-ND4, MT-ND6, MT-ND1, MT-ND2
8nad29 2411.7MT-ND2, MT-ND4, MT-ND1, MT-ND6, MT-ND5
9acetylcholine45 50 29 11 2414.7PLP1, MOG, SOD3, LTA, MBP, MAG
10plp (139-151)6010.7MBP, MOG
11c3bot (154-182)6010.7MBP, MOG
12iron45 2411.7MT-ND2, SOD3, MT-ND6, MT-ND4, MT-ND1
13ivig4510.7LTA, MAG, MBP
14mog (35-55)6010.7MOG, MBP
15threonine4510.7MBP, LTA, MT-ND2, MAG, MT-ND5, MT-ND4
16fatty acid4510.7PLP1, RCVRN, GHRH, MPZ, PMP2
17nogo-66 (1-40)6010.7MBP, MOG
18cysteine4510.6MPZ, SOD3, AQP4, PLP1, MBP, MAG
19alanine4510.6MAG, MBP, SOD3, MT-ND2, MT-ND5, MT-ND1
20ono 25066010.6MBP, MOG
21arginine4510.6CXCL11, PLP1, GHRH, MPZ, MBP, SOD3
22serine4510.6MBP, MAG, MT-ND1, MT-ND6, MPZ, MOG
23lipid4510.6MOG, LTA, MAG, MT-ND2, GHRH, MPZ
24ganglioside4510.6MPZ, MAG, MBP
25glutamate4510.5AQP4, PLP1, LTA, GHRH, MPZ, MBP
26silver4510.5MBP, MOG, PLP1
27glucose4510.5GHRH, MOG
28urea45 11 2412.4SOD3, GHRH, AQP4
29phospholipid4510.4PLP1, RCVRN, GHRH, MBP
30cholesterol45 29 11 2413.3GHRH, PLP1, SOD3, MPZ, LTA
31oligonucleotide4510.1MT-ND5, LTA, CXCL11, PLP1, AQP4

GO Terms for genes affiliated with Neuritis

Sources:
16Gene Ontology
See all sources

Cellular components related to Neuritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1myelin sheathGO:04320910.5PLP1, MPZ

Biological processes related to Neuritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1negative regulation of axonogenesisGO:05077110.4MAG, MBP
2axon ensheathmentGO:00836610.3PLP1, MBP
3membrane organizationGO:06102410.1MBP, PMP2

Molecular functions related to Neuritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1structural constituent of myelin sheathGO:01991110.4PLP1, MBP

Products for genes affiliated with Neuritis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neuritis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet