NBIA
MCID: NRD011
MIFTS: 13

Neurodegeneration with Brain Iron Accumulation Disorders (NBIA) malady

Neuronal category

Summaries for Neurodegeneration with Brain Iron Accumulation Disorders

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19GeneReviews, 33MalaCards
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MalaCards: Neurodegeneration with Brain Iron Accumulation Disorders, also known as NBIA, is related to pantothenate kinase-associated neurodegeneration and adult syndrome. An important gene associated with Neurodegeneration with Brain Iron Accumulation Disorders is WDR45 (WD repeat domain 45). Affiliated tissues include brain.

GeneReviews summary for nbia-ov

Aliases & Classifications for Neurodegeneration with Brain Iron Accumulation Disorders

Sources:
19GeneReviews, 43NIH Rare Diseases, 61UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

neurodegeneration with brain iron accumulation disorders 19
nbia 19 43
neurodegeneration with brain iron accumulation 43
hallervorden-spatz syndrome 61


Related Diseases for Neurodegeneration with Brain Iron Accumulation Disorders

Sources:
17GeneCards, 18GeneDecks
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Diseases in the neurodegeneration with brain iron accumulation 3 family:

neurodegeneration with brain iron accumulation disorders neurodegeneration with optic atrophy, childhood onset
neurodegeneration with brain iron accumulation 4 neurodegeneration with brain iron accumulation 2b
neurodegeneration with brain iron accululation 5

Diseases related to Neurodegeneration with Brain Iron Accumulation Disorders via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 32)
idRelated DiseaseScoreTop Affiliating Genes
1pantothenate kinase-associated neurodegeneration30.6PANK2
2adult syndrome10.6
3n syndrome10.6
4neurodegeneration with brain iron accumulation 310.6
5neurodegeneration with brain iron accumulation 2b10.5
6lateral sclerosis10.3
7aceruloplasminemia10.3
8amyotrophic lateral sclerosis10.3
9bod syndrome10.3
10atypical neuroaxonal dystrophy10.3
11tremor10.3
12classic pantothenate kinase associated neurodegeneration10.3
13atypical pantothenate kinase associated neurodegeneration10.3
14parkinson's disease10.3
15niemann-pick disease10.3
16superior mesenteric artery syndrome10.3
17neuroaxonal dystrophy10.3
18pick's disease10.3
19niemann–pick disease10.3
20char syndrome10.3
21parkin type of early-onset parkinson disease10.3
22acanthocytosis10.3
23young syndrome10.3
24pigmentary retinopathy10.3
25harp syndrome10.3
26chorea10.3
27brain disease10.1
28neurodegeneration with brain iron accumulation 410.1
29fatty acid hydroxylase-associated neurodegeneration10.0
30parkinson disease type 910.0
31neuroaxonal dystrophy, infantile10.0
32neurodegeneration with brain iron accululation 510.0

Graphical network of the top 20 diseases related to Neurodegeneration with Brain Iron Accumulation Disorders:



Diseases related to neurodegeneration with brain iron accumulation disorders

Clinical Features for Neurodegeneration with Brain Iron Accumulation Disorders

Drugs & Therapeutics for Neurodegeneration with Brain Iron Accumulation Disorders

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Neurodegeneration with Brain Iron Accumulation Disorders

Anatomical Context for Neurodegeneration with Brain Iron Accumulation Disorders

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33MalaCards
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MalaCards organs/tissues related to Neurodegeneration with Brain Iron Accumulation Disorders:

33
Brain

Animal Models for Neurodegeneration with Brain Iron Accumulation Disorders or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Neurodegeneration with Brain Iron Accumulation Disorders

Genetic Variations for Neurodegeneration with Brain Iron Accumulation Disorders

Expression for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

Search GEO for disease gene expression data for Neurodegeneration with Brain Iron Accumulation Disorders.

Pathways for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

Compounds for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

GO Terms for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

Sources:
16Gene Ontology
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Biological processes related to Neurodegeneration with Brain Iron Accumulation Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:0082199.0PANK2, WDR45

Products for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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  • Lysates
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Sources for Neurodegeneration with Brain Iron Accumulation Disorders

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet