NBIA
MCID: NRD011
MIFTS: 26

Neurodegeneration with Brain Iron Accumulation Disorders (NBIA) malady

Genetic diseases, Rare diseases, Neuronal diseases categories

Summaries for Neurodegeneration with Brain Iron Accumulation Disorders

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45NINDS, 20GeneReviews, 34MalaCards
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NINDS:45 Neurodegeneration with brain iron accumulation (NBIA) is a rare, inherited, neurological movement disorder characterized by an abnormal accumulation of iron in the brain and progressive degeneration of the nervous system.

MalaCards: Neurodegeneration with Brain Iron Accumulation Disorders, also known as neurodegeneration with brain iron accumulation, is related to neurodegeneration with brain iron accumulation 3 and neurodegeneration with brain iron accumulation 2b. An important gene associated with Neurodegeneration with Brain Iron Accumulation Disorders is WDR45 (WD repeat domain 45). Affiliated tissues include brain.

GeneReviews summary for nbia-ov

Aliases & Classifications for Neurodegeneration with Brain Iron Accumulation Disorders

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63UMLS, 20GeneReviews, 44NIH Rare Diseases, 21GeneTests, 23GTR, 45NINDS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

neurodegeneration with brain iron accumulation disorders 20
neurodegeneration with brain iron accumulation 44 21 23 45
nbia 20 44
hallervorden-spatz syndrome 63


Related Diseases for Neurodegeneration with Brain Iron Accumulation Disorders

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Graphical network of the top 20 diseases related to Neurodegeneration with Brain Iron Accumulation Disorders:



Diseases related to neurodegeneration with brain iron accumulation disorders

Symptoms for Neurodegeneration with Brain Iron Accumulation Disorders

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Drugs & Therapeutics for Neurodegeneration with Brain Iron Accumulation Disorders

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Genetic Tests for Neurodegeneration with Brain Iron Accumulation Disorders

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21GeneTests, 23GTR
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Genetic tests related to Neurodegeneration with Brain Iron Accumulation Disorders:

id Genetic test Affiliating Genes
1 Neurodegeneration with Brain Iron Accumulation21 23
2 Neurodegeneration with Brain Iron Accumulation Multi-Gene Panels21

Anatomical Context for Neurodegeneration with Brain Iron Accumulation Disorders

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34MalaCards
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MalaCards organs/tissues related to Neurodegeneration with Brain Iron Accumulation Disorders:

34
Brain

Animal Models for Neurodegeneration with Brain Iron Accumulation Disorders or affiliated genes

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Publications for Neurodegeneration with Brain Iron Accumulation Disorders

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53PubMed
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Articles related to Neurodegeneration with Brain Iron Accumulation Disorders:

idTitleAuthorsYear
1
Neurodegeneration with Brain Iron Accumulation Disorders Overview (23447832)
1993

Variations for Neurodegeneration with Brain Iron Accumulation Disorders

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Expression for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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Pathways for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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Compounds for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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GO Terms for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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17Gene Ontology
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Biological processes related to Neurodegeneration with Brain Iron Accumulation Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:0082199.3WDR45, PANK2

Products for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neurodegeneration with Brain Iron Accumulation Disorders

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet