NBIA
MCID: NRD011
MIFTS: 26

Neurodegeneration with Brain Iron Accumulation Disorders (NBIA) malady

Genetic diseases, Rare diseases, Neuronal diseases categories
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Summaries for Neurodegeneration with Brain Iron Accumulation Disorders

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44NINDS, 19GeneReviews, 33MalaCards
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NINDS:44 Neurodegeneration with brain iron accumulation (NBIA) is a rare, inherited, neurological movement disorder characterized by an abnormal accumulation of iron in the brain and progressive degeneration of the nervous system.

MalaCards: Neurodegeneration with Brain Iron Accumulation Disorders, also known as neurodegeneration with brain iron accumulation, is related to neurodegeneration with brain iron accumulation 3 and neurodegeneration with brain iron accumulation 2b. An important gene associated with Neurodegeneration with Brain Iron Accumulation Disorders is WDR45 (WD repeat domain 45). Affiliated tissues include brain.

GeneReviews summary for nbia-ov

Aliases & Classifications for Neurodegeneration with Brain Iron Accumulation Disorders

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62UMLS, 19GeneReviews, 43NIH Rare Diseases, 20GeneTests, 22GTR, 44NINDS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases, Rare diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

neurodegeneration with brain iron accumulation disorders 19
neurodegeneration with brain iron accumulation 43 20 22 44
nbia 19 43
hallervorden-spatz syndrome 62


Related Diseases for Neurodegeneration with Brain Iron Accumulation Disorders

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Neurodegeneration with Brain Iron Accumulation Disorders:



Diseases related to neurodegeneration with brain iron accumulation disorders

Symptoms for Neurodegeneration with Brain Iron Accumulation Disorders

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Drugs & Therapeutics for Neurodegeneration with Brain Iron Accumulation Disorders

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Search NIH Clinical Center for Neurodegeneration with Brain Iron Accumulation Disorders

Genetic Tests for Neurodegeneration with Brain Iron Accumulation Disorders

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20GeneTests, 22GTR
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Genetic tests related to Neurodegeneration with Brain Iron Accumulation Disorders:

id Genetic test Affiliating Genes
1 Neurodegeneration with Brain Iron Accumulation20 22
2 Neurodegeneration with Brain Iron Accumulation Multi-Gene Panels20

Anatomical Context for Neurodegeneration with Brain Iron Accumulation Disorders

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33MalaCards
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MalaCards organs/tissues related to Neurodegeneration with Brain Iron Accumulation Disorders:

33
Brain

Animal Models for Neurodegeneration with Brain Iron Accumulation Disorders or affiliated genes

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Publications for Neurodegeneration with Brain Iron Accumulation Disorders

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52PubMed
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Articles related to Neurodegeneration with Brain Iron Accumulation Disorders:

idTitleAuthorsYear
1
Neurodegeneration with Brain Iron Accumulation Disorders Overview (23447832)
1993

Variations for Neurodegeneration with Brain Iron Accumulation Disorders

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Expression for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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Pathways for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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Compounds for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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GO Terms for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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16Gene Ontology
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Biological processes related to Neurodegeneration with Brain Iron Accumulation Disorders according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell deathGO:0082199.3WDR45, PANK2

Products for genes affiliated with Neurodegeneration with Brain Iron Accumulation Disorders

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neurodegeneration with Brain Iron Accumulation Disorders

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet