Search: 
MCID: NRF007

Neurofibroma malady
20 genes, 3 tissues, 167 related diseases, clinical trials.

Summaries for Neurofibroma

about this section
Sources:
39NIH Rare Diseases, 59Wikipedia, 29MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
NIH Rare Diseases:39 A neurofibroma is a non-cancerous (benign) tumor that develops from the cells and tissues that cover nerves. some people who develop neurofibromas have a genetic condition known as neurofibromatosis (nf). there are different types of nf, but type 1 is the most common.

MalaCards: Neurofibroma is related to plexiform neurofibroma and neurofibromatosis. An important gene associated with Neurofibroma is NF1 (neurofibromin 1), and among its related pathways are Signaling events mediated by Stem cell factor receptor (c-Kit) and Melanocyte Development and Pigmentation. The compounds toluidine and ag-1296 have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and t cells, and related mouse phenotypes are embryogenesis and nervous system.

Wikipedia:59 A neurofibroma is a benign nerve sheath tumor in the peripheral nervous system. Usually found in... more...

Aliases & Classifications for Neurofibroma

about this section
Sources:
8Disease Ontology, 39NIH Rare Diseases, 10DISEASES, 41Novoseek, 45Orphanet, 56UMLS, 52SNOMED-CT, 31MeSH, 36NCIt
See all sources

Aliases & Descriptions:

neurofibroma 8 39 10 41 45 56



External Ids:

Disease Ontology8 DOID:962
NCIt36 C3272

Related Diseases for Neurofibroma

about this section
Sources:
16GeneCards, 17GeneDecks
See all sources

Diseases related to neurofibroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 167)
idRelated DiseaseScoreTop Affiliating Genes
1plexiform neurofibroma34.3TP73, NF1, PDGFRA, MMP13
2neurofibromatosis34.1MMP13, PDGFRA, NF1, NF2, GHR, S100B
3malignant peripheral nerve sheath tumor31.9NF1
4neurofibrosarcoma28.5TP73, NF2, NF1
5microphthalmia28.3KIT, S100B, MITF
6meningioma28.3S100B, S100A1, TP73, NF2, NF1, PDPN
7gastrointestinal stromal tumor28.2KIT, KITLG, S100B, S100A1, NF2, PDGFRA
8astrocytoma28.2S100B, TP73, GHR, MET, NF2, NF1
9acoustic neuroma27.7NF2, NF1
10melanoma27.5KIT, KITLG, S100B, S100A1, TP73, GHR
11histiocytosis14.0S100B
12neuroepithelioma14.0NF1
13chondroma14.0PDGFRA
14synovial sarcoma14.0CD34
15perivascular epithelioid cell tumor14.0MITF
16hemangioendothelioma14.0CD34
17perineurioma14.0S100B, CD34
18myelofibrosis13.9PDGFRA
19pancreatitis13.9KITLG
20arthritis13.9MMP13
21rosai-dorfman disease13.9S100B
22hepatitis13.9GHR
23granular cell tumor13.9S100A1, S100B
24glomus tumor13.9S100A1
25endometrial carcinoma13.9APOD, CD34
26angiosarcoma13.9CD34, PDPN, PDGFRA
27hemangioblastoma13.9S100B, PDPN
28multiple sclerosis13.9KITLG, CNP
29fibromatosis13.9KIT, S100A1, CD34
30malignant fibroxanthoma13.9S100B, S100A1, F13A1
31juvenile xanthogranuloma13.9F13A1, S100B
32chordoma13.9S100B, S100A1, PDGFRA
33carney triad13.9PDGFRA, KIT
34anaplastic astrocytoma13.9APOD, PDGFRA, TP73
35gallbladder cancer13.9PDPN
36salivary gland cancer13.9MET
37carney complex13.9F13A1, S100A1, S100B
38retinoblastoma13.9MITF, NF1, TP73
39pilocytic astrocytoma13.9S100B, TP73, NF1, APOD
40langerhans-cell histiocytosis13.8F13A1, S100A1, S100B
41ductal carcinoma in situ13.8PDPN
42pituitary adenoma13.8GHR, TP73
43esophageal cancer13.8TP73, MMP13
44neurilemmoma13.8NF2, NF1, CD34
45angiomyolipoma13.8KIT, S100A1, MITF
46mesenchymal cell neoplasm13.8KIT, PDGFRA, CD34
47renal oncocytoma13.8S100A1
48fibrosarcoma13.8GHR, PDGFRA, MMP13, CD34
49dermatitis13.8F13A1
50down syndrome13.8S100A1, S100B

Graphical network of the top 20 diseases related to neurofibroma:



Diseases related to neurofibroma

Symptoms for Neurofibroma

about this section

Drugs & Therapeutics for Neurofibroma

about this section
Sources:
5CenterWatch, 38NIH Clinical Center, 6ClinicalTrials, 56UMLS, 37NDF-RT
See all sources

Approved drugs:

Search CenterWatch for neurofibroma

Drug clinical trials:

Search ClinicalTrials for neurofibroma

Search NIH Clinical Center for neurofibroma

Search CenterWatch for neurofibroma

Genetic Tests for Neurofibroma

about this section

Anatomical Context for Neurofibroma

about this section
Sources:
29MalaCards
See all sources

MalaCards organs/tissues related to neurofibroma:

29
Skin, T cells, Endothelial

Animal Models for Neurofibroma or affiliated genes

about this section
Sources:
33MGI, 26inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to neurofibroma:

33 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1
embryogenesis phenotype
MP:000538010.5MET, GHR, GLI1
2
nervous system phenotype
MP:000363110.4APOD, TP73, CNP, NF1, CNTN2, GLI1
3
hearing/vestibular/ear phenotype
MP:000537710.4APOD, MITF, NF2, TP73, KITLG, KIT
4
limbs/digits/tail phenotype
MP:000537110.4PDGFRA, MMP13, MITF, KIT, KITLG, GHR
5
tumorigenesis
MP:000200610.4CD34, KITLG, PDGFRA, NF1, KIT, TP73
6
pigmentation phenotype
MP:000118610.3MITF, PDGFRA, NF1
7
craniofacial phenotype
MP:000538210.3MET, NF2, TP73, NF1, MITF, PDGFRA
8
respiratory system phenotype
MP:000538810.3CNP, KIT, GLI1, MET, NF2, F13A1
9
reproductive system phenotype
MP:000538910.3CNP, F13A1, MITF, NF2, GHR, TP73
10
endocrine/exocrine gland phenotype
MP:000537910.3KIT, KITLG, TP73, NF1, MITF, PDGFRA
11
skeleton phenotype
MP:000539010.3KITLG, PDPN, TP73, GHR, KIT, NF2
12
integument phenotype
MP:001077110.2NF1, MITF, KITLG, PDPN, S100B, KIT
13
hematopoietic system phenotype
MP:000539710.2CD34, KITLG, CNP, TP73, F13A1, PDGFRA
14
digestive/alimentary phenotype
MP:000538110.2PDGFRA, MET, GLI1, PDPN, CNP, TP73
15
cardiovascular system phenotype
MP:000538510.2KIT, KITLG, S100A1, GHR, MET, NF1
16
vision/eye phenotype
MP:000539110.1MITF, CNP, KITLG, KIT, NF1, NF2
17
growth/size phenotype
MP:000537810.1MITF, NF1, NF2, MET, TP73, KIT
18
immune system phenotype
MP:000538710.1PDGFRA, CD34, KIT, PDPN, KITLG, TP73
19
behavior/neurological phenotype
MP:000538610.1CNP, KIT, S100B, S100A1, TP73, GHR
20
muscle phenotype
MP:000536910.1CNP, PDGFRA, NF1, MET, S100A1, KIT
21
homeostasis/metabolism phenotype
MP:000537610.1PDPN, MMP13, APOD, F13A1, CD34, CNP
22
renal/urinary system phenotype
MP:000536710.0PDGFRA, KIT, NF1, NF2, MET, GLI1
23
mortality/aging
MP:001076810.0KIT, KITLG, TP73, CNP, F13A1, APOD
24
normal phenotype
MP:00028739.9S100B, PDGFRA, MITF, NF1, MET, S100A1

Publications for Neurofibroma

about this section
Sources:
47PubMed
See all sources

Articles related to neurofibroma:

(show top 50)    (show all 81)
idTitleAuthorsYearAffiliating Genes
1Screening for mutation site on the type I neurofibroma tosis gene in a family. (22207399)Lv M.... Li S.2012NF1
2Biallelic inactivation of NF1 in a sporadic plexiform neurofibroma. (22585738)Beert E.... Debiec-Rychter M.2012NF1
3Distinguishing neurofibroma from desmoplastic melanom a: the value of the CD34 fingerprint. (21457155)Yeh I.... McCalmont T.H.2011CD34
4S100B and neurofibromin immunostaining and X-inactiva tion patterns of laser-microdissected cells indicate a multicellular origin of some NF1-associated neurofibromas. (21674567)Tucker T.... Friedman J.M.2011S100B, NF1
5Perinatal or adult Nf1 inactivation using tamoxifen-i nducible PlpCre each cause neurofibroma formation. (21551249)Mayes D.A.... Ratner N.2011NF1
6Clinico-pathological and biomolecular findings in Italian patients with multiple cutaneous neurofibromas. (21838856)Ponti G.... Seidenari S.2011NF1
7A molecular analysis of individuals with neurofibroma tosis type 1 (NF1) and optic pathway gliomas (OPGs), and an assessment of genot ype-phenotype correlations. (21278392)Sharif S.... Evans D.G.2011NF1
8Podoplanin and CD34 in peripheral nerve sheath tumour s: focus on neurofibromatosis 1-associated atypical neurofibroma. (20821344)Naber U.... Hagel C.2011CD34, PDPN
9Plexiform neurofibroma genesis: questions of Nf1 gene dose and hyperactive mast cells. (20571392)Staser K.... Clapp D.W.2010NF1
10Primary localised pleural neurofibroma: expanding the spectrum of spindle cell tumours of the pleura. (20154031)Langman G.... Papadaki L.2010S100B
11Solitary submucous neurofibroma of the mandible: revi ew of the literature and report of a rare case. (19912641)Depprich R.... Handschel J.2009S100B
12Tranilast, an anti-allergic drug, down-regulates the growth of cultured neurofibroma cells derived from neurofibromatosis type 1. (19282654)Yamamoto M.... Yamamoto Y.2009TGFB1, KITLG, AREG
13Identification of growth hormone receptor in plexiform neurofibromas of patients with neurofibromatosis type 1. (18297205)Cunha K.S.... Fonseca E.C.2008GHR
14Nf1 mutation expands an EGFR-dependent peripheral nerve progenitor that confers neurofibroma tumorigenic potential. (19041782)Williams J.P.... Ratner N.2008EGFR, NF1
15Germline and somatic NF1 gene mutations in plexiform neurofibromas. (18484666)Upadhyaya M.... Mautner V.2008NF1
16A gastrointestinal stromal tumor of the stomach morphologically resembling a neurofibroma: demonstration of a novel platelet-derived growth factor receptor alpha exon 18 mutation. (18657298)Liu T.... Holden J.A.2008PDGFRA, KIT
17Zebrafish with mutations in mismatch repair genes dev elop neurofibromas and other tumors. (18593904)Feitsma H.... Cuppen E.2008MSH6
18Colocalized cellular schwannoma and plexiform neurofibroma in the absence of neurofibromatosis. Case report. (17695403)Spinner R.J.... Gutmann D.H.2007NF1, NF2
19NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight. (17215493)Dombi E.... Widemann B.C.2007NF1
20An absence of cutaneous neurofibromas associated with a 3-bp inframe deletion in exon 17 of the NF1 gene (c.2970-2972 delAAT): evidence of a clinically significant NF1 genotype-phenotype correlation. (17160901)Upadhyaya M.... Messiaen L.2007NF1
21Nf1+/- mast cells induce neurofibroma like phenotypes through secreted TGF-beta signaling. (16835260)Yang F.C.... Clapp D.W.2006NF1
22Somatic loss of wild type NF1 allele in neurofibromas: Comparison of NF1 microdeletion and non-microdeletion patients. (16830335)De Raedt T.... Legius E.2006NF1
23Bladder neurofibroma: case report and bibliographic review (17190213)Cabrera Castillo P.M.... De La PeA+a Barthel J.J.2006S100B
24Tight junction proteins and perineurial cells in neurofibromas. (16087703)Pummi K.P.... Peltonen S.A.2006TJP1, CLDN5, CLDN3
25Pigmented neurofibroma: review of Japanese patients with an analysis of melanogenesis demonstrating coexpression of c-met protooncogene and microphthalmia-associated transcription factor. (16112003)Motoi T.... Fukayama M.2005MITF, NF2, MLANA
26Biallelic somatic inactivation of the NF1 gene through chromosomal translocations in a sporadic neurofibroma. (15986446)Storlazzi C.T.... Mertens F.2005NF1
27Apolipoprotein D is down-regulated during malignant transformation of neurofibromas. (16153462)Hunter S.... Varma V.2005APOD
28Elevated ankyrin G in a plexiform neurofibroma and neuromas associated with pain. (15519868)Kretschmer T.... Kline D.G.2004ANK3
29Gamma interferon gene transfection efficiently inhibits proliferation of neurofibroma cell lines in vitro. (12692353)Nakayama J.... Kuroki M.2003ISG20
30NF1 mutations and clinical spectrum in patients with spinal neurofibromas. (12746402)Kluwe L.... Mautner V.F.2003NF1
31Aberrant CpG island methylation in neurofibromas and neurofibrosarcomas. (12883734)Gonzalez-Gomez P.... Rey J.A.2003TP73
32Identification of growth hormone receptor in localised neurofibromas of patients with neurofibromatosis type 1. (14514779)Cunha K.S.... Da Fonseca E.C.2003GHR
33PDGF-BB induces MAP kinase phosphorylation and VEGF expression in neurofibroma-derived cultured cells from patients with neurofibromatosis 1. (12484433)Kotsuji-Maruyama T.... Otsuka F.2002MAPK10
34Losses in chromosomes 17, 19, and 22q in neurofibromatosis type 1 and sporadic neurofibromas: a comparative genomic hybridization analysis. (12237234)Koga T.... Kikuchi M.2002NF1
35Gamma interferon directly inhibits the growth of neurofibroma cells in vitro. (12392063)Nakayama J.... Terao H.2002IFNG
36NF1 deletions in S-100 protein-positive and negative cells of sporadic and neurofibromatosis 1 (NF1)-associated plexiform neurofibromas and malignant peripheral nerve sheath tumors. (11438454)Perry A.... Gutmann D.H.2001S100B
37CDKN2A germline splicing mutation affecting both p16(ink4) and p14(arf) RNA processing in a melanoma/neurofibroma kindred. (11433531)Petronzelli F.... Genuardi M.2001CDKN2A
38Pigmented (melanotic) neurofibroma: a clinicopathologic and immunohistochemical analysis of 19 lesions from 17 patients. (10716146)Fetsch J.F.... Miettinen M.2000TYR, S100A1
39Single cell Ras-GTP analysis reveals altered Ras activity in a subpopulation of neurofibroma Schwann cells but not fibroblasts. (10900196)Sherman L.S.... Ratner N.2000NF1, RASA2
40Local injection of recombinant human stem cell factor promotes human skin mast cell survival and neurofibroma cell proliferation in the transplanted neurofibroma in nude mice. (10421057)Demitsu T.... Yaoita H.1999KITLG
41Deletions of the INK4A gene occur in malignant peripheral nerve sheath tumors but not in neurofibromas. (10595915)Kourea H.P.... Woodruff J.M.1999CDKN2A
42Quantitative analysis of NF1 and OMGP gene transcripts in sporadic gliomas, sporadic meningiomas and neurofibromatosis type 1-associated plexiform neurofibromas. (10378372)Peters N.... von Deimling A.1999GAPDH, B2M
43Loss of NF1 allele in Schwann cells but not in fibroblasts derived from an NF1-associated neurofibroma. (10451710)Kluwe L.... Mautner V.F.1999NF1
44Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. (10595918)Nielsen G.P.... Louis D.N.1999CDKN2A
45Ras activation in astrocytomas and neurofibromas. (9827227)Guha A.1998EGFR, EGF, VEGFA
46A novel glial growth inhibitory factor, gliostatin, derived from neurofibroma. (1613506)Asai K.... Kato T.1992TYMP
47Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse. (1432035)Lee J.K.... Martuza R.L.1992B2M
48The neurofibroma in von Recklinghausen neurofibromatosis has a unicellular origin. (1715669)Skuse G.R.... Rowley P.T.1991NF1
49Neurofibromas and neurotized melanocytic nevi are immunohistochemically distinct neoplasms. (1693815)Gray M.H.... Hsu A.1990S100B, MBP
50Immunohistochemical demonstration of factor XIIIa exp ression in neurofibromas. A practical means of differentiating these tumors fro m neurotized melanocytic nevi and schwannomas. (1690969)Gray M.H.... Hsu A.1990F13A1

Variations for Neurofibroma

about this section

Expression for genes affiliated with Neurofibroma

about this section
Sources:
1BioGPS
See all sources
Expression patterns in normal tissues for genes affiliated with Neurofibroma

Pathways for genes affiliated with Neurofibroma

about this section
Sources:
34NCBI BioSystems Database, 48QIAGEN, 27KEGG, 4Cell Signaling Technology, 50Reactome
See all sources

Pathways related to neurofibroma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Signaling events mediated by Stem cell factor receptor (c-Kit)34
Hide members
10.3KIT, KITLG, MITF
2
Melanocyte Development and Pigmentation48
10.3KIT, KITLG, MITF
3
Hematopoietic cell lineage27
10.3CD34, KITLG, KIT
4
C-MYB transcription factor network34
10.3CD34, KITLG, KIT
5
Glioma27
Hide members
10.3PDGFRA, MITF, NF1, MET
6
Pathways in cancer27
10.3MITF, MET, GLI1, KITLG
7
Tyrosine Kinases / Adaptors4
10.3KIT, KITLG, MET, PDGFRA
8
Basal cell carcinoma27
Hide members
10.3MITF, GLI1, KITLG, KIT
9
PIP3 activates AKT signaling50
Hide members
10.2KIT, KITLG, S100B, GHR, PDGFRA
10
Nanog in Mammalian ESC Pluripotency48
Hide members
10.2KIT, KITLG, TP73, MET, PDGFRA

Compounds for genes affiliated with Neurofibroma

about this section
Sources:
41Novoseek, 46PharmGKB, 11DrugBank, 55Tocris Bioscience, 22HMDB, 2BitterDB
See all sources

Compounds related to neurofibroma according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idCompoundScoreTop Affiliating Genes
1toluidine4110.8KITLG
2ag-12964110.7KIT, PDGFRA, KITLG
3reticulin4110.7CD34, F13A1, S100B
4fluorochrome4110.7KIT, CD34, GHR
5rhodamine 12341 4611.7KITLG, CD34, KIT
6b 7234110.7PDPN, S100A1, S100B, F13A1
7agarose4110.7KIT, KITLG, S100B, APOD, MMP13
8imatinib41 46 1112.7KIT, S100B, PDGFRA, TP73, KITLG
9bromodeoxyuridine4110.6CNP, CNTN2
10silver4110.6S100A1, CD34, F13A1, MITF
11p0034110.6GHR, KIT, S100B, TP73
12rapamycin41 5511.6PDGFRA, KITLG, NF2, MET, KIT, NF1
13pd 98,0594110.6MMP13, KIT, KITLG
14p0024110.6KIT, TP73, MET, MMP13
15cysteine4110.6MMP13, NF2, MET, CNTN2, NF1, GHR
16zinc41 2211.6MMP13, GLI1, S100A1, GHR, S100B
17agar4110.6MET, KITLG, CNTN2, CD34, NF2
18ribonucleic acid4110.6KITLG, KIT, MMP13, MET, GHR
19hematoxylin4110.6S100A1, S100B, KIT, PDPN, F13A1, CD34
20vegf4110.6MET, S100B, PDGFRA, MMP13, CD34, CNTN2
2112-o-tetradecanoylphorbol 13-acetate4110.5MET, MITF, MMP13, CD34, CNTN2
22thymidine41 2211.5CD34, MMP13, GHR, MET, CNTN2, KIT
23monochloroacetic acid4110.5KITLG, KIT
24phosphatidylinositol4110.5MMP13, GLI1, NF1, MET, GHR, KITLG
25cyclic amp41 2211.5S100B, CNTN2, MMP13, MITF, NF1, GHR
26arginine4110.5CNTN2, NF1, GHR, TP73, S100B, MITF
27steroid4110.5CNTN2, KITLG, NF1, S100B, GHR, KIT
28methylcellulose4110.5CD34, KITLG, KIT
29nitric oxide41 11 2212.5MET, KIT, KITLG, S100B, S100A1, GHR
30cycloheximide4110.5MMP13, MET, GHR, KITLG, CNTN2, KIT
31glycogen41 2211.5S100B, S100A1, KIT, GHR, MET
32actinomycin d4110.5KIT, KITLG, TP73, MET, MMP13
33testosterone41 11 2212.4S100B, GHR, KIT, KITLG, MET, APOD
34lipid4110.4CNP, APOD, MITF, NF1, MET, KITLG
35serine4110.4KIT, GHR, CNTN2, S100B, KITLG, MMP13
36oxygen41 2211.4MET, KITLG, S100B, GHR, MITF, MMP13
37threonine4110.4NF2, CNTN2
38progesterone41 55 11 2213.4F13A1, APOD, CD34, S100A1, NF2, MET
39oligonucleotide4110.4MITF, MMP13, KIT, PDGFRA, TP73, GHR
40ccl44110.3MMP13, MET, S100B
41glucose4110.3KITLG, S100B, KIT, GLI1, APOD, GHR
42iron41 2211.3S100B, GHR, S100A1, KITLG, F13A1
43calcium41 46 11 2213.3CNTN2, KIT, MMP13, PDGFRA, MITF, NF1
44fatty acid4110.3APOD, S100B, GHR, NF1, TP73
45retinoic acid41 55 2212.3KIT, KITLG, S100B, S100A1, TP73, GHR
46estrogen4110.2MMP13, PDGFRA, MET, GHR, TP73, S100A1
47phenylalanine4110.2GHR, KIT, MMP13, MET
48tyrosine4110.1S100A1, MITF, NF2, KIT, KITLG, MMP13
49paraffin4110.1MMP13, S100A1, CD34, KIT, KITLG, S100B
50chloramphenicol41 2 1112.0CNTN2, GHR, S100B, TP73

GO Terms for genes affiliated with Neurofibroma

about this section
Sources:
15Gene Ontology
See all sources

Cellular components related to neurofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1filopodium membraneGO:03152710.4PDPN, NF2
2extracellular spaceGO:00561510.2CNP, KIT, KITLG, S100B, GHR, MMP13
3neuronal cell bodyGO:04302510.2S100B, GHR, APOD, CNTN2
4integral to plasma membraneGO:00588710.1SEMA4F, GHR, MET, PDGFRA, PDPN, CD34
5perinuclear region of cytoplasmGO:0484719.9CNP, CD34, APOD, NF2, S100B
6plasma membraneGO:0058869.9KIT, KITLG, SEMA4F, GHR, MET, NF2

Biological processes related to neurofibroma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of DNA replicationGO:04574010.5PDGFRA, GLI1, KITLG
2germ cell programmed cell deathGO:03523410.5KITLG, KIT
3positive regulation of phospholipase C activityGO:01086310.5KIT, PDGFRA
4activation of MAPK activityGO:00018710.5MET, GHR, TP73, KIT
5cell proliferationGO:00828310.4KITLG, S100B, MET, PDPN, CD34
6hemopoiesisGO:03009710.4CD34, KITLG, KIT
7regulation of neuronal synaptic plasticityGO:04816810.4CNTN2, S100B
8lung developmentGO:03032410.3GLI1, PDGFRA, PDPN
9negative regulation of cell-matrix adhesionGO:00195310.3NF1, NF2
10negative regulation of MAPK cascadeGO:04340910.1NF1, NF2

Molecular functions related to neurofibroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1S100 protein bindingGO:04454810.4S100A1, S100B
2protein bindingGO:0055159.6APOD, KIT, KITLG, S100B, S100A1, TP73

Products for genes affiliated with Neurofibroma

about this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Neurofibroma

about this section
3CDC
13ExPASy
14FMA
21HGMD
22HMDB
23ICD10
24ICD10 via Orphanet
25ICD9CM
27KEGG
31MeSH
32MESH via Orphanet
33MGI
36NCIt
37NDF-RT
40NINDS
41Novoseek
43OMIM
44OMIM via Orphanet
47PubMed
48QIAGEN
53SNOMED-CT via Orphanet
56UMLS
57UMLS via Orphanet
Browse MalaCards: 1-9 | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z