MCID: NRG002
MIFTS: 53

Neurogenic Bladder malady

Neuronal diseases, Nephrological diseases categories
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Summaries for Neurogenic Bladder

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Wikipedia:65 Neurogenic bladder dysfunction, sometimes simply referred to as neurogenic bladder, is a dysfunction of... more...

MalaCards based summary: Neurogenic Bladder, also known as neurogenic dysfunction of the urinary bladder, is related to vesicoureteral reflux and cystitis. An important gene associated with Neurogenic Bladder is P2RX2 (purinergic receptor P2X, ligand-gated ion channel, 2), and among its related pathways is Cell adhesion ECM remodeling. The drugs hyoscyamine sulfate and baclofen and the compounds succinylcholine and atropine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, prostate and testes, and related mouse phenotype respiratory system.

Aliases & Classifications for Neurogenic Bladder

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 62UMLS, 34MeSH, 57SNOMED-CT, 39NCIt, 27ICD9CM
See all sources

Neurogenic Bladder, Aliases & Descriptions:

Name: Neurogenic Bladder 8 10
Neurogenic Dysfunction of the Urinary Bladder 8 62
Urinary Bladder Disorder, Neurogenic 62
Neurogenic Urinary Bladder Disorder 8
 
Neurogenic Urinary Bladder 62
Neurogenic Bladder Nos 8
Neuropathic Bladder 8
Bladder Neurogenic 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Nephrological diseases


External Ids:

Disease Ontology8 DOID:12143
MeSH34 D001750
NCIt39 C79696
ICD9CM27 596.54

Related Diseases for Neurogenic Bladder

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Diseases related to Neurogenic Bladder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1vesicoureteral reflux31.2MEOX2, TMEM173
2cystitis30.8CASK, P2RX2
3spinal cord injury10.8
4bacteriuria10.6
5myelomeningocele10.6
6bladder disease10.6
7multiple sclerosis10.6
8spina bifida10.6
9urethritis10.5
10prostatitis10.5
11herpes zoster10.4
12cerebritis10.4
13intrinsic asthma10.3IGHE
14eosinophilic gastroenteritis10.3IGHE
15cerebral palsy10.3
16urofacial syndrome10.3
17cervicitis10.3
18hinman syndrome10.3
19imperforate anus10.2
20systemic lupus erythematosus10.2
21perinephritis10.2
22bladder neck obstruction10.2
23lupus erythematosus10.2
24prostatic hypertrophy10.2
25sarcoidosis10.2
26adult polyglucosan body disease10.2
27occult spinal dysraphism10.2
28spasticity10.2
29blindness10.2
30allergic bronchopulmonary aspergillosis10.2IGHE, IGES
31autosomal dominant hyper ige syndrome10.2IGES, IGHE
32kimura disease10.2IGES, IGHE
33urethral stricture10.2KLK3, KLHL24
34asthma10.2IGES, IGHE
35urticaria10.2IGHE
36conjunctivitis10.2IGES, IGHE
37food allergy10.2IGES, IGHE
38hypereosinophilic syndrome10.2IGHE, IGES
39bronchiectasis10.2IGHE, IGES
40otitis media10.1IGHE, IGES
41mastocytosis10.1IGHE, CMA1
42sinusitis10.1IGHE, IGES
43vernal keratoconjunctivitis10.1CMA1, IGHE, IGES
44respiratory failure10.1IGES, IGHE, CMA1
45rhinitis10.1CMA1, IGHE, IGES
46atopy10.1IGES, IGHE, CMA1
47renal tubular acidosis10.1
48spondylosis10.1
49radiculopathy10.1
50achondroplasia10.1

Graphical network of the top 20 diseases related to Neurogenic Bladder:



Diseases related to neurogenic bladder

Symptoms for Neurogenic Bladder

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Drugs & Therapeutics for Neurogenic Bladder

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Drug clinical trials:

Search ClinicalTrials for Neurogenic Bladder

Search NIH Clinical Center for Neurogenic Bladder

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Neurogenic Bladder

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Anatomical Context for Neurogenic Bladder

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MalaCards organs/tissues related to Neurogenic Bladder:

32
Spinal cord, Prostate, Testes, Colon, Brain, Kidney

Animal Models for Neurogenic Bladder or affiliated genes

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MGI Mouse Phenotypes related to Neurogenic Bladder:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0CASK, MEOX2, P2RX2, CHRM2

Publications for Neurogenic Bladder

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Articles related to Neurogenic Bladder:

(show top 50)    (show all 522)
idTitleAuthorsYear
1
Strategies for prevention of urinary tract infections in neurogenic bladder dysfunction. (25064790)
2014
2
Stress urinary incontinence as a rare presentation of large prostatic stones in neurogenic bladder: implications and management. (23749833)
2013
3
Symptoms and side effects: delicate balance in the management of patients with neurogenic bladder. (24055263)
2013
4
Neurogenic bladder in lyme disease. (23346488)
2012
5
Predictive factors for percutaneous nephrolithotomy outcomes in neurogenic bladder population. (22250919)
2012
6
Cerebral palsy, neurogenic bladder, and outcomes of lifetime care. (22788916)
2012
7
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
8
Neurogenic bladder in children: basic principles, new therapeutic trends. (22182847)
2011
9
Suprapubic cystostomy for neurogenic bladder using Lowsley retractor method: a procedure revisited. (21908021)
2011
10
Long-term results of bulking agent injection for persistent incontinence in cases of neurogenic bladder dysfunction. (20022056)
2010
11
Treating the adult neurogenic bladder. Preface. (20955899)
2010
12
Management goals for the spina bifida neurogenic bladder: a review from infancy to adulthood. (20955904)
2010
13
What is the most effective management of neurogenic bladder dysfunction? (19282439)
2009
14
Fetal urinary ascites in a neonate without detectable obstructive uropathy or neurogenic bladder etiology. (19027364)
2009
15
Intravesical oxybutynin in the pediatric neurogenic bladder. (19901914)
2009
16
Management of pediatric neurogenic bladder. (19440150)
2009
17
Neurogenic bladder dysfunction. Bladder stimulation for neurogenic bladder. (19383741)
2009
18
Treatment of the neurogenic bladder in spina bifida. (18350321)
2008
19
Re: Al Mosawi AJ: Identification of nonneurogenic neurogenic bladder in infants (Urology 70: 335-356, 2007). (18291506)
2008
20
Outcomes and quality of life of adults undergoing continent catheterizable vesicostomy for neurogenic bladder. (17707889)
2007
21
Clozapine for the treatment of neurogenic bladder. (17245773)
2007
22
Rehabilitating the neurogenic bladder: the role of artificial neural reflex pathways in children with spina bifida. (16526998)
2006
23
Neurogenic bladder dysfunction after sacrococcygeal teratoma resection. (16406929)
2006
24
Urological surveillance and management of patients with neurogenic bladder: Results of a survey among practicing urologists in Canada. (17076944)
2006
25
Repeated intradetrusor botulinum toxin type A in children with neurogenic bladder due to myelomeningocele. (16469632)
2006
26
L-methionine in patients with neurogenic bladder disorders: Executive summary of final report A04-02, Version 1.0 (23101071)
2005
27
Can higher doses of oxybutynin improve efficacy in neurogenic bladder? (14713802)
2004
28
Sacral neuromodulation for neurogenic bladder dysfunction in children. (15371787)
2004
29
Editorial: use of neuronal stem cells to treat neurogenic bladder due to spinal cord injury. (14501782)
2003
30
Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. (12036401)
2002
31
The management of neurogenic bladder and sexual dysfunction after spinal cord injury. (11805620)
2001
32
Hematuria as a complication of sudden decompression of chronically distended bladder in a child with neurogenic bladder dysfunction. (10888467)
2000
33
Bladder-wall abscess in a girl with neurogenic bladder. (10663866)
2000
34
Nitrofurantoin prophylaxis for bacteriuria and urinary tract infection in children with neurogenic bladder on intermittent catheterization. (9580774)
1998
35
Management of vesicoureteral reflux secondary to neurogenic bladder. (9799381)
1998
36
An alternative ureteroileal reimplantation used in augmentation cystoplasty for neurogenic bladder with bilateral vesicoureteral reflux. (9751368)
1998
37
Multiple sclerosis and the neurogenic bladder. (9894113)
1998
38
The neurogenic bladder in spinal cord injury--pattern and management. (8893929)
1996
39
Artificial urinary sphincter in patients with neurogenic bladder dysfunction. (8800894)
1996
40
Neurogenic bladder in patients with acquired immunodeficiency syndrome. (7647807)
1995
41
Responses of the human neurogenic bladder to KCl, carbachol, ATP and CaCl2. (8131037)
1994
42
DDAVP in the urological management of the difficult neurogenic bladder in spinal cord injury: preliminary report. (7869058)
1994
43
Synchronous cystoscopy and cystometry in the management of neurogenic bladder dysfunction. (8326570)
1993
44
Distention of the posterior urethra: association with nonneurogenic neurogenic bladder (Hinman syndrome). (1523292)
1992
45
The use of intravesical oxybutynin chloride in children with neurogenic bladder. (1861294)
1991
46
Clean, intermittent catheterization of infants with neurogenic bladder. (2740179)
1989
47
Bladder-outlet reconstruction in neurogenic bladder due to myelomeningocele. (3337968)
1988
48
A critical reappraisal of cystometry in neurogenic bladder diseases. (3686758)
1987
49
Enterocystoplasty in the management and reconstruction of the pediatric neurogenic bladder. (3820015)
1987
50
Neurogenic bladder in Rocky Mountain spotted fever. (6824406)
1983

Variations for Neurogenic Bladder

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Expression for genes affiliated with Neurogenic Bladder

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Expression patterns in normal tissues for genes affiliated with Neurogenic Bladder

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Pathways for genes affiliated with Neurogenic Bladder

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Pathways related to Neurogenic Bladder according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7KLK3, CMA1

Compounds for genes affiliated with Neurogenic Bladder

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Compounds related to Neurogenic Bladder according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1succinylcholine44 50 28 1112.8CHRM2, IGHE
2atropine44 28 1111.8CHRM2, TAC3
3propofol44 50 1111.8CHRM2, IGHE
4tetrodotoxin44 61 2811.8TAC3, CHRM2
5ozone449.7IGES, CHRM2
6pertussis449.7CHRM2, IGHE
7capsaicin44 2810.6TAC3, CMA1, IGHE
8gnrh449.5TAC3, KLK3, CHRM2
9methacholine44 50 1111.4IGHE, IGES
10aprotinin44 1110.4KLK3, IGHE
11allergens449.3CMA1, IGHE, IGES
12histamine44 28 2410.9IGES, IGHE, CMA1, CHRM2
13nitric oxide44 24 1110.9IGES, CHRM2, MEOX2, TAC3
14acetylcholine44 50 28 24 1112.9IGES, IGHE, CHRM2, TAC3
15estrogen448.9IGHE, CHRM2, KLK3, TAC3
16lactate448.7KLK3, IGHE, IGES
17calcium44 50 24 1111.4CMA1, CHRM2, P2RX2, CASK, TAC3

GO Terms for genes affiliated with Neurogenic Bladder

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Cellular components related to Neurogenic Bladder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1presynaptic membraneGO:0427349.7CASK, P2RX2

Molecular functions related to Neurogenic Bladder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1serine-type peptidase activityGO:0082369.7KLK3, CMA1

Products for genes affiliated with Neurogenic Bladder

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  • Antibodies
  • Proteins
  • Lysates

Sources for Neurogenic Bladder

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet