MCID: NRG002
MIFTS: 51

Neurogenic Bladder malady

Neuronal diseases, Nephrological diseases categories

Summaries for Neurogenic Bladder

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66Wikipedia, 34MalaCards
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Wikipedia:66 Neurogenic bladder dysfunction, sometimes simply referred to as neurogenic bladder, is a dysfunction of... more...

MalaCards: Neurogenic Bladder, also known as neurogenic dysfunction of the urinary bladder, is related to vesicoureteral reflux and cystitis. An important gene associated with Neurogenic Bladder is P2RX2 (purinergic receptor P2X, ligand-gated ion channel, 2), and among its related pathways is Cell adhesion ECM remodeling. The drugs hyoscyamine sulfate and baclofen and the compounds succinylcholine and atropine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, prostate and testes, and related mouse phenotype respiratory system.

Aliases & Classifications for Neurogenic Bladder

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9Disease Ontology, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 28ICD9CM, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Nephrological diseases


Aliases & Descriptions:

neurogenic bladder 9 11
neurogenic dysfunction of the urinary bladder 9
neurogenic urinary bladder disorder 9
neurogenic urinary bladder 63
neurogenic bladder nos 9
neuropathic bladder 9
bladder neurogenic 46


External Ids:

Disease Ontology9 DOID:12143
ICD9CM28 596.54
NCIt41 C79696
MeSH36 D001750

Related Diseases for Neurogenic Bladder

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Sources:
18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Neurogenic Bladder:



Diseases related to neurogenic bladder

Symptoms for Neurogenic Bladder

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Drugs & Therapeutics for Neurogenic Bladder

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Neurogenic Bladder

Drug clinical trials:

Search ClinicalTrials for Neurogenic Bladder

Search NIH Clinical Center for Neurogenic Bladder

Search CenterWatch for Neurogenic Bladder

Inferred drug relations via UMLS63/NDF-RT42:

Genetic Tests for Neurogenic Bladder

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Anatomical Context for Neurogenic Bladder

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34MalaCards
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MalaCards organs/tissues related to Neurogenic Bladder:

34
Spinal cord, Prostate, Testes, Colon, Brain, Kidney

Animal Models for Neurogenic Bladder or affiliated genes

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38MGI
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MGI Mouse Phenotypes related to Neurogenic Bladder:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0CASK, MEOX2, P2RX2, CHRM2

Publications for Neurogenic Bladder

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53PubMed
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Articles related to Neurogenic Bladder:

(show top 50)    (show all 499)
idTitleAuthorsYear
1
Stress urinary incontinence as a rare presentation of large prostatic stones in neurogenic bladder: implications and management. (23749833)
2013
2
Symptoms and side effects: delicate balance in the management of patients with neurogenic bladder. (24055263)
2013
3
Neurogenic bladder in lyme disease. (23346488)
2012
4
Predictive factors for percutaneous nephrolithotomy outcomes in neurogenic bladder population. (22250919)
2012
5
Cerebral palsy, neurogenic bladder, and outcomes of lifetime care. (22788916)
2012
6
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
7
Neurogenic bladder in children: basic principles, new therapeutic trends. (22182847)
2011
8
Suprapubic cystostomy for neurogenic bladder using Lowsley retractor method: a procedure revisited. (21908021)
2011
9
Long-term results of bulking agent injection for persistent incontinence in cases of neurogenic bladder dysfunction. (20022056)
2010
10
Treating the adult neurogenic bladder. Preface. (20955899)
2010
11
Management goals for the spina bifida neurogenic bladder: a review from infancy to adulthood. (20955904)
2010
12
What is the most effective management of neurogenic bladder dysfunction? (19282439)
2009
13
Fetal urinary ascites in a neonate without detectable obstructive uropathy or neurogenic bladder etiology. (19027364)
2009
14
Intravesical oxybutynin in the pediatric neurogenic bladder. (19901914)
2009
15
Management of pediatric neurogenic bladder. (19440150)
2009
16
Treatment of the neurogenic bladder in spina bifida. (18350321)
2008
17
Re: Al Mosawi AJ: Identification of nonneurogenic neurogenic bladder in infants (Urology 70: 335-356, 2007). (18291506)
2008
18
Outcomes and quality of life of adults undergoing continent catheterizable vesicostomy for neurogenic bladder. (17707889)
2007
19
Clozapine for the treatment of neurogenic bladder. (17245773)
2007
20
Rehabilitating the neurogenic bladder: the role of artificial neural reflex pathways in children with spina bifida. (16526998)
2006
21
Neurogenic bladder dysfunction after sacrococcygeal teratoma resection. (16406929)
2006
22
Urological surveillance and management of patients with neurogenic bladder: Results of a survey among practicing urologists in Canada. (17076944)
2006
23
Repeated intradetrusor botulinum toxin type A in children with neurogenic bladder due to myelomeningocele. (16469632)
2006
24
L-methionine in patients with neurogenic bladder disorders: Executive summary of final report A04-02, Version 1.0 (23101071)
2005
25
Can higher doses of oxybutynin improve efficacy in neurogenic bladder? (14713802)
2004
26
Sacral neuromodulation for neurogenic bladder dysfunction in children. (15371787)
2004
27
Catheter policies for management of long term voiding problems in adults with neurogenic bladder disorders. (15106248)
2004
28
Editorial: use of neuronal stem cells to treat neurogenic bladder due to spinal cord injury. (14501782)
2003
29
Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. (12036401)
2002
30
The management of neurogenic bladder and sexual dysfunction after spinal cord injury. (11805620)
2001
31
Hematuria as a complication of sudden decompression of chronically distended bladder in a child with neurogenic bladder dysfunction. (10888467)
2000
32
Bladder-wall abscess in a girl with neurogenic bladder. (10663866)
2000
33
Nitrofurantoin prophylaxis for bacteriuria and urinary tract infection in children with neurogenic bladder on intermittent catheterization. (9580774)
1998
34
Management of vesicoureteral reflux secondary to neurogenic bladder. (9799381)
1998
35
An alternative ureteroileal reimplantation used in augmentation cystoplasty for neurogenic bladder with bilateral vesicoureteral reflux. (9751368)
1998
36
Multiple sclerosis and the neurogenic bladder. (9894113)
1998
37
The neurogenic bladder in spinal cord injury--pattern and management. (8893929)
1996
38
Artificial urinary sphincter in patients with neurogenic bladder dysfunction. (8800894)
1996
39
Neurogenic bladder in patients with acquired immunodeficiency syndrome. (7647807)
1995
40
Perinephric urinoma secondary to neurogenic bladder in myelodysplasia. (7815619)
1995
41
Responses of the human neurogenic bladder to KCl, carbachol, ATP and CaCl2. (8131037)
1994
42
DDAVP in the urological management of the difficult neurogenic bladder in spinal cord injury: preliminary report. (7869058)
1994
43
Synchronous cystoscopy and cystometry in the management of neurogenic bladder dysfunction. (8326570)
1993
44
The use of intravesical oxybutynin chloride in children with neurogenic bladder. (1861294)
1991
45
Clean, intermittent catheterization of infants with neurogenic bladder. (2740179)
1989
46
Bladder-outlet reconstruction in neurogenic bladder due to myelomeningocele. (3337968)
1988
47
A critical reappraisal of cystometry in neurogenic bladder diseases. (3686758)
1987
48
Enterocystoplasty in the management and reconstruction of the pediatric neurogenic bladder. (3820015)
1987
49
Neurogenic bladder in Rocky Mountain spotted fever. (6824406)
1983
50
VOIDING PRESSURE AND URINARY FLOW IN PROSTATIC HYPERTROPHY AND IN NEUROGENIC BLADDER DISORDERS. (14227133)
1964

Variations for Neurogenic Bladder

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Expression for genes affiliated with Neurogenic Bladder

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neurogenic Bladder

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Pathways for genes affiliated with Neurogenic Bladder

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51PathCards, 61Thomson Reuters, 13EMD Millipore
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Pathways related to Neurogenic Bladder according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.7KLK3, CMA1

Compounds for genes affiliated with Neurogenic Bladder

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46Novoseek, 52PharmGKB, 30IUPHAR, 12DrugBank, 62Tocris Bioscience, 25HMDB
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Compounds related to Neurogenic Bladder according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1succinylcholine46 52 30 1212.8IGHE, CHRM2
2atropine46 30 1211.8CHRM2, TAC3
3propofol46 52 1211.8IGHE, CHRM2
4tetrodotoxin46 62 3011.8TAC3, CHRM2
5ozone469.7IGES, CHRM2
6pertussis469.7CHRM2, IGHE
7capsaicin46 3010.6TAC3, IGHE, CMA1
8gnrh469.5TAC3, KLK3, CHRM2
9methacholine46 52 1211.4IGES, IGHE
10aprotinin46 1210.4KLK3, IGHE
11allergens469.3IGHE, CMA1, IGES
12histamine46 30 2510.9IGHE, IGES, CMA1, CHRM2
13nitric oxide46 25 1210.9MEOX2, TAC3, CHRM2, IGES
14acetylcholine46 52 30 25 1212.9IGES, IGHE, CHRM2, TAC3
15estrogen468.9TAC3, KLK3, CHRM2, IGHE
16lactate468.7KLK3, IGES, IGHE
17calcium46 52 25 1211.4CMA1, CHRM2, P2RX2, CASK, TAC3

GO Terms for genes affiliated with Neurogenic Bladder

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17Gene Ontology
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Cellular components related to Neurogenic Bladder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1presynaptic membraneGO:0427349.7CASK, P2RX2

Molecular functions related to Neurogenic Bladder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1serine-type peptidase activityGO:0082369.7KLK3, CMA1

Products for genes affiliated with Neurogenic Bladder

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neurogenic Bladder

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet