MCID: NRG002
MIFTS: 44

Neurogenic Bladder malady

Neuronal diseases, Nephrological diseases categories

Aliases & Classifications for Neurogenic Bladder

About this section
Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 38NCIt, 33MeSH, 27ICD9CM
See all sources

Neurogenic Bladder, Aliases & Descriptions:

Name: Neurogenic Bladder 9 11
Neurogenic Dysfunction of the Urinary Bladder 9
Neurogenic Urinary Bladder Disorder 9
Neurogenic Urinary Bladder 60
 
Neurogenic Bladder Nos 9
Neuropathic Bladder 9
Bladder Neurogenic 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases, Nephrological diseases


External Ids:

Disease Ontology9 DOID:12143
NCIt38 C79696
MeSH33 D001750
ICD9CM27 596.54

Summaries for Neurogenic Bladder

About this section


Wikipedia:63 Neurogenic bladder dysfunction, sometimes simply referred to as neurogenic bladder, is a dysfunction of... more...

MalaCards based summary: Neurogenic Bladder, also known as neurogenic dysfunction of the urinary bladder, is related to vesicoureteral reflux and cystitis. An important gene associated with Neurogenic Bladder is P2RX2 (purinergic receptor P2X, ligand-gated ion channel, 2), and among its related pathways is Cell adhesion ECM remodeling. The drugs hyoscyamine sulfate and baclofen and the compounds succinylcholine and atropine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, prostate and testes, and related mouse phenotype respiratory system.

Related Diseases for Neurogenic Bladder

About this section

Diseases related to Neurogenic Bladder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 104)
idRelated DiseaseScoreTop Affiliating Genes
1vesicoureteral reflux31.3MEOX2, TMEM173
2cystitis30.8CASK, P2RX2
3spinal cord injury10.8
4bacteriuria10.6
5myelomeningocele10.6
6bladder disease10.6
7urethritis10.6
8prostatitis10.5
9polyglucosan body disease, adult form10.4
10herpes zoster10.4
11cerebritis10.4
12hinman syndrome10.4
13intrinsic asthma10.3IGHE
14eosinophilic gastroenteritis10.3IGHE
15urofacial syndrome 110.3
16cerebral palsy10.3
17cervicitis10.3
18imperforate anus10.2
19systemic lupus erythematosus10.2
20oculodentodigital dysplasia10.2
21perinephritis10.2
22bladder neck obstruction10.2
23lupus erythematosus10.2
24prostatic hypertrophy10.2
25occult spinal dysraphism10.2
26spasticity10.2
27blindness10.2
28allergic bronchopulmonary aspergillosis10.2IGES, IGHE
29hyper-ige recurrent infection syndrome10.2IGHE, IGES
30kimura disease10.2IGHE, IGES
31urethral stricture10.2KLHL24, KLK3
32asthma10.2IGES, IGHE
33urticaria10.2IGHE
34conjunctivitis10.2IGHE, IGES
35food allergy10.2IGHE, IGES
36hypereosinophilic syndrome10.2IGHE, IGES
37bronchiectasis10.1IGHE, IGES
38otitis media10.1IGHE, IGES
39mastocytosis10.1CMA1, IGHE
40sinusitis10.1IGES, IGHE
41vernal keratoconjunctivitis10.1IGHE, CMA1, IGES
42respiratory failure10.1IGHE, IGES, CMA1
43achondroplasia10.1
44renal tubular acidosis10.1
45spondylosis10.1
46radiculopathy10.1
47hydronephrosis10.1
48chronic pyelonephritis10.1
49seminoma10.1
50urinary tract obstruction10.1

Graphical network of the top 20 diseases related to Neurogenic Bladder:



Diseases related to neurogenic bladder

Symptoms for Neurogenic Bladder

About this section

Drugs & Therapeutics for Neurogenic Bladder

About this section

Drug clinical trials:

Search ClinicalTrials for Neurogenic Bladder

Search NIH Clinical Center for Neurogenic Bladder

Inferred drug relations via UMLS60/NDF-RT39:

Genetic Tests for Neurogenic Bladder

About this section

Anatomical Context for Neurogenic Bladder

About this section

MalaCards organs/tissues related to Neurogenic Bladder:

31
Spinal cord, Prostate, Testes, Colon, Brain, Kidney, Small intestine

Animal Models for Neurogenic Bladder or affiliated genes

About this section

MGI Mouse Phenotypes related to Neurogenic Bladder:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053889.0CASK, MEOX2, P2RX2, CHRM2

Publications for Neurogenic Bladder

About this section

Articles related to Neurogenic Bladder:

(show top 50)    (show all 535)
idTitleAuthorsYear
1
A systematic review and comparison of questionnaires in the management of spinal cord injury, multiple sclerosis and the neurogenic bladder. (25620137)
2015
2
Screening for depression and anxiety in childhood neurogenic bladder dysfunction. (25824880)
2015
3
Strategies for prevention of urinary tract infections in neurogenic bladder dysfunction. (25064790)
2014
4
Treatment outcome of neurogenic bladder dysfunction in children; a five-year experience. (25562028)
2014
5
A foreseeable tissue engineering approach to overcome the neurogenic bladder-related detrusor/urethral rhabdosphincter dyssynergia. (25426476)
2014
6
Stress urinary incontinence as a rare presentation of large prostatic stones in neurogenic bladder: implications and management. (23749833)
2013
7
Neurogenic bladder in lyme disease. (23346488)
2012
8
Predictive factors for percutaneous nephrolithotomy outcomes in neurogenic bladder population. (22250919)
2012
9
Management of detrusor external sphincter dyssynergia in neurogenic bladder. (22081065)
2011
10
Neurogenic bladder in children: basic principles, new therapeutic trends. (22182847)
2011
11
Suprapubic cystostomy for neurogenic bladder using Lowsley retractor method: a procedure revisited. (21908021)
2011
12
Long-term results of bulking agent injection for persistent incontinence in cases of neurogenic bladder dysfunction. (20022056)
2010
13
Treating the adult neurogenic bladder. Preface. (20955899)
2010
14
Management goals for the spina bifida neurogenic bladder: a review from infancy to adulthood. (20955904)
2010
15
What is the most effective management of neurogenic bladder dysfunction? (19282439)
2009
16
Fetal urinary ascites in a neonate without detectable obstructive uropathy or neurogenic bladder etiology. (19027364)
2009
17
Intravesical oxybutynin in the pediatric neurogenic bladder. (19901914)
2009
18
Management of pediatric neurogenic bladder. (19440150)
2009
19
Neurogenic bladder dysfunction. Bladder stimulation for neurogenic bladder. (19383741)
2009
20
Treatment of the neurogenic bladder in spina bifida. (18350321)
2008
21
Re: Al Mosawi AJ: Identification of nonneurogenic neurogenic bladder in infants (Urology 70: 335-356, 2007). (18291506)
2008
22
Outcomes and quality of life of adults undergoing continent catheterizable vesicostomy for neurogenic bladder. (17707889)
2007
23
Clozapine for the treatment of neurogenic bladder. (17245773)
2007
24
Rehabilitating the neurogenic bladder: the role of artificial neural reflex pathways in children with spina bifida. (16526998)
2006
25
Neurogenic bladder dysfunction after sacrococcygeal teratoma resection. (16406929)
2006
26
Urological surveillance and management of patients with neurogenic bladder: Results of a survey among practicing urologists in Canada. (17076944)
2006
27
L-methionine in patients with neurogenic bladder disorders: Executive summary of final report A04-02, Version 1.0 (23101071)
2005
28
Can higher doses of oxybutynin improve efficacy in neurogenic bladder? (14713802)
2004
29
Sacral neuromodulation for neurogenic bladder dysfunction in children. (15371787)
2004
30
Editorial: use of neuronal stem cells to treat neurogenic bladder due to spinal cord injury. (14501782)
2003
31
Neurogenic bladder, neurogenic bowel, and sexual dysfunction in people with spinal cord injury. (12036401)
2002
32
The management of neurogenic bladder and sexual dysfunction after spinal cord injury. (11805620)
2001
33
Hematuria as a complication of sudden decompression of chronically distended bladder in a child with neurogenic bladder dysfunction. (10888467)
2000
34
Nitrofurantoin prophylaxis for bacteriuria and urinary tract infection in children with neurogenic bladder on intermittent catheterization. (9580774)
1998
35
Management of vesicoureteral reflux secondary to neurogenic bladder. (9799381)
1998
36
An alternative ureteroileal reimplantation used in augmentation cystoplasty for neurogenic bladder with bilateral vesicoureteral reflux. (9751368)
1998
37
Multiple sclerosis and the neurogenic bladder. (9894113)
1998
38
The neurogenic bladder in spinal cord injury--pattern and management. (8893929)
1996
39
Artificial urinary sphincter in patients with neurogenic bladder dysfunction. (8800894)
1996
40
Neurogenic bladder in patients with acquired immunodeficiency syndrome. (7647807)
1995
41
Responses of the human neurogenic bladder to KCl, carbachol, ATP and CaCl2. (8131037)
1994
42
DDAVP in the urological management of the difficult neurogenic bladder in spinal cord injury: preliminary report. (7869058)
1994
43
Synchronous cystoscopy and cystometry in the management of neurogenic bladder dysfunction. (8326570)
1993
44
Distention of the posterior urethra: association with nonneurogenic neurogenic bladder (Hinman syndrome). (1523292)
1992
45
The use of intravesical oxybutynin chloride in children with neurogenic bladder. (1861294)
1991
46
Clean, intermittent catheterization of infants with neurogenic bladder. (2740179)
1989
47
Bladder-outlet reconstruction in neurogenic bladder due to myelomeningocele. (3337968)
1988
48
A critical reappraisal of cystometry in neurogenic bladder diseases. (3686758)
1987
49
Enterocystoplasty in the management and reconstruction of the pediatric neurogenic bladder. (3820015)
1987
50
Neurogenic bladder in Rocky Mountain spotted fever. (6824406)
1983

Variations for Neurogenic Bladder

About this section

Expression for genes affiliated with Neurogenic Bladder

About this section
Search GEO for disease gene expression data for Neurogenic Bladder.

Pathways for genes affiliated with Neurogenic Bladder

About this section

Pathways related to Neurogenic Bladder according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Metalloproteases in connective tissue degradation
9.7KLK3, CMA1

Compounds for genes affiliated with Neurogenic Bladder

About this section

Compounds related to Neurogenic Bladder according to GeneCards Suite gene sharing:

(show all 17)
idCompoundScoreTop Affiliating Genes
1succinylcholine43 49 28 1212.8IGHE, CHRM2
2atropine43 28 1211.8CHRM2, TAC3
3propofol43 49 1211.8IGHE, CHRM2
4tetrodotoxin43 59 2811.8TAC3, CHRM2
5ozone439.7IGES, CHRM2
6pertussis439.7CHRM2, IGHE
7capsaicin43 2810.6TAC3, IGHE, CMA1
8gnrh439.5TAC3, KLK3, CHRM2
9methacholine43 49 1211.4IGES, IGHE
10aprotinin43 1210.4KLK3, IGHE
11allergens439.3IGHE, CMA1, IGES
12histamine43 28 2410.9IGHE, IGES, CMA1, CHRM2
13nitric oxide43 24 1210.9MEOX2, TAC3, CHRM2, IGES
14acetylcholine43 49 28 24 1212.9IGES, IGHE, CHRM2, TAC3
15estrogen438.9TAC3, KLK3, CHRM2, IGHE
16lactate438.7KLK3, IGES, IGHE
17calcium43 49 24 1211.4CMA1, CHRM2, P2RX2, CASK, TAC3

GO Terms for genes affiliated with Neurogenic Bladder

About this section

Cellular components related to Neurogenic Bladder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1presynaptic membraneGO:00427349.7CASK, P2RX2

Molecular functions related to Neurogenic Bladder according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1serine-type peptidase activityGO:00082369.7KLK3, CMA1

Products for genes affiliated with Neurogenic Bladder

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Neurogenic Bladder

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet