MCID: NRG004
MIFTS: 23

Neurogenic Diabetes Insipidus malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Neurogenic Diabetes Insipidus

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Aliases & Descriptions for Neurogenic Diabetes Insipidus:

Name: Neurogenic Diabetes Insipidus 45
Central Diabetes Insipidus 45 65
Diabetes Insipidus Neurohypophyseal 45
Neurohypophyseal Diabetes Insipidus 45
 
Diabetes Insipidus Cranial Type 45
Diabetes Insipidus Neurogenic 45
Pituitary Diabetes Insipidus 45

Characteristics:

HPO:

61


Classifications:



Summaries for Neurogenic Diabetes Insipidus

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NIH Rare Diseases:45 Neurogenic diabetes insipidus is a disease that causes frequent urination. this type of diabetes insipidus results from damage to the pituitary gland, which disrupts the normal storage and release of antidiuretic hormone (adh). when this hormone reaches the kidneys, it directs them to make less urine. damage to the pituitary gland can be caused by different diseases as well as by head injuries, neurosurgery, or genetic disorders. to treat the adh deficiency that results from any kind of damage to the pituitary, a synthetic hormone called desmopressin can be taken by an injection, a nasal spray, or a pill. last updated: 5/18/2011

MalaCards based summary: Neurogenic Diabetes Insipidus, also known as central diabetes insipidus, is related to diabetes insipidus, neurohypophyseal and hereditary central diabetes insipidus, and has symptoms including hypokalemia, polydipsia and alkalosis. An important gene associated with Neurogenic Diabetes Insipidus is AVP (Arginine Vasopressin). Affiliated tissues include pituitary, kidney and brain.

Wikipedia:68 Neurogenic diabetes insipidus, more commonly known as central diabetes insipidus, is due to a lack of... more...

Related Diseases for Neurogenic Diabetes Insipidus

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Graphical network of the top 20 diseases related to Neurogenic Diabetes Insipidus:



Diseases related to neurogenic diabetes insipidus

Symptoms for Neurogenic Diabetes Insipidus

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HPO human phenotypes related to Neurogenic Diabetes Insipidus:

(show all 6)
id Description Frequency HPO Source Accession
1 hypokalemia HP:0002900
2 polydipsia HP:0001959
3 alkalosis HP:0001948
4 central diabetes insipidus HP:0000863
5 hydronephrosis HP:0000126
6 polyuria HP:0000103

Drugs & Therapeutics for Neurogenic Diabetes Insipidus

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Drugs for Neurogenic Diabetes Insipidus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Natriuretic AgentsPhase 31403
2VasopressinsPhase 3260
3HemostaticsPhase 31082
4Deamino Arginine VasopressinPhase 368
5Arginine VasopressinPhase 3264
6CoagulantsPhase 31042
7arginineNutraceuticalPhase 3364
8Vasoconstrictor Agents1303

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).CompletedNCT01280188Phase 3
2Vasopressin Deficiency in Hemorrhagic ShockCompletedNCT01107314
3Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes InsipidusCompletedNCT00004363
4Copeptin During a Standardized Psychological Stress TestCompletedNCT01866137
5Evaluation of Plasma Volume Using Ultrasound in Disorders of Fluid With SodiumActive, not recruitingNCT01547650

Search NIH Clinical Center for Neurogenic Diabetes Insipidus

Genetic Tests for Neurogenic Diabetes Insipidus

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Anatomical Context for Neurogenic Diabetes Insipidus

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MalaCards organs/tissues related to Neurogenic Diabetes Insipidus:

33
Pituitary, Kidney, Brain, Testes, Breast, Prostate, B cells

Animal Models for Neurogenic Diabetes Insipidus or affiliated genes

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Publications for Neurogenic Diabetes Insipidus

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Articles related to Neurogenic Diabetes Insipidus:

(show all 19)
idTitleAuthorsYear
1
Bilateral Posterior Scleritis: Analysis of 18 Cases from a Large Cohort of Posterior Scleritis. (26471249)
2015
2
Successful treatment of diffuse large B-cell lymphoma in a patient with ataxia telangiectasia using rituximab. (23389503)
2013
3
Solute carrier family 26 member a2 (Slc26a2) protein functions as an electroneutral SOFormula/OH-/Cl- exchanger regulated by extracellular Cl-. (22190686)
2012
4
Homocysteine and folate levels as indicators of cerebrovascular accident. (22282692)
2010
5
Detection of molluscum contagiosum virus gene transcripts by in situ hybridization. (19243920)
2009
6
Polymorphisms in von Willebrand factor gene promoter influence the glucocorticoid-induced increase in von Willebrand factor: the lesson learned from Cushing syndrome. (18173757)
2008
7
Primary adenoid cystic carcinoma of the mandible: case report and review of the literature. (19022143)
2008
8
Proteomics of nipple aspirate fluid, breast cyst fluid, milk, and colostrum. (21136738)
2007
9
Thrombospondin-1 is induced in rat myocardial infarction and its induction is accelerated by ischemia/reperfusion. (16179730)
2005
10
Interleukin-18 concentrations and the pathogenesis of periodontal disease. (15898940)
2005
11
Direct involvement of protein myristoylation in myristoylated alanine-rich C kinase substrate (MARCKS)-calmodulin interaction. (14506265)
2003
12
Wilms' tumor suppressor (WT1) is a mediator of neuronal degeneration associated with the pathogenesis of Alzheimer's disease. (12914969)
2003
13
Fas and Fas ligand: expression and soluble circulating levels in cutaneous malignant melanoma. (12100188)
2002
14
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. (12391164)
2002
15
Localization of hyaluronan in pseudocapsule from total hip arthroplasty. (10379317)
1999
16
Update on acute and chronic endophthalmitis. (10599651)
1999
17
Purification and characterization of human cleavage factor Im involved in the 3' end processing of messenger RNA precursors. (8626397)
1996
18
Mediation of glucocorticoid receptor function by transforming growth factor beta I expression in human PC-3 prostate cancer cells. (7753711)
1995
19
Problems involved in re-laparotomy for congenital biliary atresia: with special reference to postoperative ascending cholangitis. (3388986)
1988

Variations for Neurogenic Diabetes Insipidus

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Expression for genes affiliated with Neurogenic Diabetes Insipidus

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Search GEO for disease gene expression data for Neurogenic Diabetes Insipidus.

Pathways for genes affiliated with Neurogenic Diabetes Insipidus

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GO Terms for genes affiliated with Neurogenic Diabetes Insipidus

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Sources for Neurogenic Diabetes Insipidus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet