MCID: NRG004
MIFTS: 26

Neurogenic Diabetes Insipidus malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Neurogenic Diabetes Insipidus

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Aliases & Descriptions for Neurogenic Diabetes Insipidus:

Name: Neurogenic Diabetes Insipidus 46
Diabetes Insipidus Neurohypophyseal 46 25
Central Diabetes Insipidus 46 66
Neurohypophyseal Diabetes Insipidus 46
 
Diabetes Insipidus Cranial Type 46
Diabetes Insipidus Neurogenic 46
Pituitary Diabetes Insipidus 46

Characteristics:

HPO:

62


Classifications:



Summaries for Neurogenic Diabetes Insipidus

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NIH Rare Diseases:46 Neurogenic diabetes insipidus is a disease that causes frequent urination. this type of diabetes insipidus results from damage to the pituitary gland, which disrupts the normal storage and release of antidiuretic hormone (adh). when this hormone reaches the kidneys, it directs them to make less urine. damage to the pituitary gland can be caused by different diseases as well as by head injuries, neurosurgery, or genetic disorders. to treat the adh deficiency that results from any kind of damage to the pituitary, a synthetic hormone called desmopressin can be taken by an injection, a nasal spray, or a pill. last updated: 5/18/2011

MalaCards based summary: Neurogenic Diabetes Insipidus, also known as diabetes insipidus neurohypophyseal, is related to diabetes insipidus, neurohypophyseal and hereditary central diabetes insipidus, and has symptoms including polyuria, hydronephrosis and central diabetes insipidus. An important gene associated with Neurogenic Diabetes Insipidus is AVP (Arginine Vasopressin). Affiliated tissues include pituitary, brain and kidney.

Wikipedia:69 Neurogenic diabetes insipidus, more commonly known as central diabetes insipidus, is due to a lack of... more...

Related Diseases for Neurogenic Diabetes Insipidus

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Diseases related to Neurogenic Diabetes Insipidus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
idRelated DiseaseScoreTop Affiliating Genes
1diabetes insipidus, neurohypophyseal11.6
2hereditary central diabetes insipidus11.2
3acquired central diabetes insipidus11.2
4diabetes insipidus10.5
5diabetes insipidus, nephrogenic10.2
6systemic lupus erythematosus9.9
7lung cancer9.9
8brain injury9.9
9traumatic brain injury9.9
10cerebritis9.9
11lupus erythematosus9.9
12encephalitis9.9
13encephalopathy9.9

Graphical network of diseases related to Neurogenic Diabetes Insipidus:



Diseases related to neurogenic diabetes insipidus

Symptoms for Neurogenic Diabetes Insipidus

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HPO human phenotypes related to Neurogenic Diabetes Insipidus:

(show all 6)
id Description Frequency HPO Source Accession
1 polyuria HP:0000103
2 hydronephrosis HP:0000126
3 central diabetes insipidus HP:0000863
4 alkalosis HP:0001948
5 polydipsia HP:0001959
6 hypokalemia HP:0002900

Drugs & Therapeutics for Neurogenic Diabetes Insipidus

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Drugs for Neurogenic Diabetes Insipidus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1arginineNutraceuticalPhase 3393
2
Chlorpropamide594-20-22727
Synonyms:
1-((p-Chlorophenyl)sulfonyl)-3-propylurea
1-(4-Chlorophenylsulfonyl)-3-propylurea
1-(4-chlorophenyl)sulfonyl-3-propylurea
1-(P-Chlorobenzenesulfonyl)-3-propylurea
1-(P-Chlorophenylsulfonyl)-3-propylurea
1-(p-Chlorobenzenesulfonyl)-3-propylurea
1-(p-Chlorobenzensulfonyl)-3-propylurea
1-(p-Chlorophenylsulfonyl)-3-propylurea
1-(para-Chlorophenylsulfonyl)-3-propylurea
1-Propyl-3-(P-chlorobenzenesulfonyl)urea
1-Propyl-3-(p-chlorobenzenesulfonyl)urea
1-[(4-chlorobenzene)sulfonyl]-3-propylurea
1-[p-Chlorobenzenesulfonyl]-3-propylurea
1-p-Chlorophenyl-3-(propylsulfonyl)urea
4-Chloro-4-((propylamino)carbonyl)benzenesulfonamide
4-Chloro-N-((propylamino)carbonyl)benzenesulfonamide
4-chloro-N-((Propylamino)carbonyl)benzenesulfonamide
4-chloro-N-(propylcarbamoyl)benzenesulfonamide
4-chloro-N-[(Propylamino)carbonyl]benzenesulfonamide
4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide
94-20-2
AB00051944
AC1L1EBW
AC1Q2Y2Z
AKOS001482739
Adiaben
Apo-Chlorpropamide
Apotex Brand of Chlorpropamide
Asucrol
BPBio1_000359
BRD-K97746869-001-05-6
BRN 2218363
BSPBio_000325
BSPBio_002013
Bio-0154
Bioglumin
Byk Gulden Brand of Chlorpropamide
C 1290
C10H13ClN2O3S
C1220
C1290_FLUKA
C1290_SIGMA
CAS-94-20-2
CCRIS 155
CHEBI:3650
CHEMBL498
CHLORPROPAMIDE USP
CID2727
CPD000058364
Catanil
Chlorodiabina
Chloronase
Chloropropamide
Chlorporpamide
Chlorpropamid
Chlorpropamide
Chlorpropamide (JP15/USP/INN)
Chlorpropamide Bp/ Usp
Chlorpropamide [INN:BAN:JAN]
Chlorpropamidum
Chlorpropamidum [INN-Latin]
Clorpropamid
Clorpropamida
Clorpropamida [INN-Spanish]
Clorpropamide
Clorpropamide [DCIT]
Clorpropamide [Italian]
D00271
D002747
DB00672
Diabaril
Diabechlor
Diabenal
Diabenese
Diabeneza
Diabet-Pages
Diabetoral
Diabexan
Diabinese
Diabinese (TN)
Diamel Ex
DivK1c_000513
Dynalase
EINECS 202-314-5
EU-0100229
Farmasierra Brand of Chlorpropamide
Glisema
Glucamide
HMS1569A07
 
HMS1920M05
HMS2091E08
HMS501J15
HSDB 2051
IDI1_000513
Insogen
Insulase
KBio1_000513
KBio2_000624
KBio2_002273
KBio2_003192
KBio2_004841
KBio2_005760
KBio2_007409
KBio3_001233
KBio3_002753
KBioGR_000808
KBioGR_002273
KBioSS_000624
KBioSS_002274
LS-1959
Lopac-C-1290
Lopac0_000229
MLS000028395
MLS001148665
Meldian
Melitase
Mellinese
Millinese
MolPort-001-779-601
N-(4-Chlorophenylsulfonyl)-N'-propylurea
N-(4-Chlorophenylsulfonyl)-n'-propylurea
N-(P-Chlorobenzenesulfonyl)-n'-propylurea
N-(p-Chlorobenzenesulfonyl)-N'-propylurea
N-Propyl-N'-(p-chlorobenzenesulfonyl)urea
N-Propyl-N'-p-chlorphenylsulfonylcarbamide
N-Propyl-n'-(P-chlorobenzenesulfonyl)urea
N-Propyl-n'-P-chlorophenylsulfonylcarbamide
N3-Butyl-N1-p-chlorobenzenesulfonylure a
N3-Butyl-N1-p-chlorobenzenesulfonylurea
NCGC00015216-01
NCGC00015216-02
NCGC00015216-03
NCGC00015216-07
NCGC00015216-12
NCGC00021451-03
NCGC00021451-04
NCGC00021451-05
NCGC00021451-06
NCGC00021451-07
NCGC00021451-08
NCI-C01752
NINDS_000513
NSC 44634
NSC 626720
NSC44634
NSC626720
Novo-Propamide
Oradian
P 607
Pfizer Brand of Chlorpropamide
Prestwick0_000323
Prestwick1_000323
Prestwick2_000323
Prestwick3_000323
Prestwick_684
Prodiaben
SAM002554890
SMR000058364
SPBio_000018
SPBio_002246
SPECTRUM1500185
STK857458
Spectrum2_000089
Spectrum3_000347
Spectrum4_000284
Spectrum5_000719
Spectrum_000144
Stabinol
U-3818
U-9818
UNII-WTM2C3IL2X
WLN: GR DSWMVM3
ZINC01530599
cMAP_000007
chlorporpamide
chlorpropamide
dia benese
n-Propyl-N'-p-chlorophenylsulfonylcarbamide
n-propyl-N'-p-chlorophenylsu lfonylcarbamide

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Minirin Melt in Japanese Patients With Central Diabetes Insipidus (CDI).CompletedNCT01280188Phase 3
2Vasopressin Deficiency in Hemorrhagic ShockCompletedNCT01107314
3Study of the Pathogenesis and Pathophysiology of Familial Neurohypophyseal Diabetes InsipidusCompletedNCT00004363
4Copeptin During a Standardized Psychological Stress TestCompletedNCT01866137
5Evaluation of Plasma Volume Using Ultrasound in Disorders of Fluid With SodiumActive, not recruitingNCT01547650

Search NIH Clinical Center for Neurogenic Diabetes Insipidus

Genetic Tests for Neurogenic Diabetes Insipidus

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Genetic tests related to Neurogenic Diabetes Insipidus:

id Genetic test Affiliating Genes
1 Diabetes Insipidus, Neurohypophyseal Type25

Anatomical Context for Neurogenic Diabetes Insipidus

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MalaCards organs/tissues related to Neurogenic Diabetes Insipidus:

34
Pituitary, Brain, Kidney, Testes, Liver, Lung

Animal Models for Neurogenic Diabetes Insipidus or affiliated genes

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Publications for Neurogenic Diabetes Insipidus

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Articles related to Neurogenic Diabetes Insipidus:

(show all 20)
idTitleAuthorsYear
1
Buccally Administered Intranasal Desmopressin Acetate for the Treatment of Neurogenic Diabetes Insipidus in Infancy. (27011115)
2016
2
A case of hypokalemic paralysis in a patient with neurogenic diabetes insipidus. (24707338)
2014
3
Late onset of familial neurogenic diabetes insipidus in monozygotic twins. (24156710)
2013
4
Central neurogenic diabetes insipidus, syndrome of inappropriate secretion of antidiuretic hormone, and cerebral salt-wasting syndrome in traumatic brain injury. (22467619)
2012
5
Treatment of neurogenic diabetes insipidus. (22071315)
2011
6
Neurogenic diabetes insipidus presenting in a patient with subacute liver failure: a case report. (20673320)
2010
7
Neurogenic diabetes insipidus. (17080264)
2006
8
Identification of a new mutation (CysII6Gly) in a family with neurogenic diabetes insipidus]. (10827849)
2000
9
Neurogenic diabetes insipidus in patients with systemic lupus erythematosus. (9709193)
1998
10
Neurogenic diabetes insipidus in children with hypoxic encephalopathy: six new cases and a review of the literature. (8929736)
1996
11
Continuous infusion of vasopressin in comatose children with neurogenic diabetes insipidus. (8821902)
1995
12
Neurogenic diabetes insipidus in a child with fatal Coxsackie virus B1 encephalitis. (8821910)
1995
13
Neurogenic diabetes insipidus: an unusual clinical presentation of small cell lung cancer. (8390898)
1993
14
Neurogenic diabetes insipidus in an initially healthy neonate. (2588585)
1989
15
Neurogenic diabetes insipidus in a sheep. (3944284)
1986
16
Idiopathic neurogenic diabetes insipidus in a cat. (6639529)
1983
17
Occurrence of diabetes mellitus in neurogenic diabetes insipidus. (7331673)
1981
18
Nephrology forum: neurogenic diabetes insipidus. (480789)
1979
19
The use of 1-desamino-8-D-arginine vasopressin (DDAVP) in the management of neurogenic diabetes insipidus (multiple etiologies in pediatric patients). (492086)
1979
20
Neurogenic diabetes insipidus: management with dDAVP (1-desamino-8-D arginine vasopressin). (626447)
1978

Variations for Neurogenic Diabetes Insipidus

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Expression for genes affiliated with Neurogenic Diabetes Insipidus

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Search GEO for disease gene expression data for Neurogenic Diabetes Insipidus.

Pathways for genes affiliated with Neurogenic Diabetes Insipidus

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GO Terms for genes affiliated with Neurogenic Diabetes Insipidus

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Sources for Neurogenic Diabetes Insipidus

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet