CDI
MCID: NRH001
MIFTS: 57

Neurohypophyseal Diabetes Insipidus (CDI) malady

Endocrine diseases, Rare diseases, Neuronal diseases categories
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Summaries for Neurohypophyseal Diabetes Insipidus

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MalaCards based summary: Neurohypophyseal Diabetes Insipidus, also known as central diabetes insipidus, is related to panhypopituitarism and diabetes insipidus, and has symptoms including pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria, diabetes insipidus and autosomal dominant inheritance. An important gene associated with Neurohypophyseal Diabetes Insipidus is AVP (arginine vasopressin), and among its related pathways are Vasopressin-regulated water reabsorption and Regulation of Water Balance by Renal Aquaporins. The compounds atosiban and oxytocin have been mentioned in the context of this disorder. Affiliated tissues include pituitary and testes, and related mouse phenotypes are integument and growth/size/body.

Descriptions from OMIM:46 125700,304900

Aliases & Classifications for Neurohypophyseal Diabetes Insipidus

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Sources:
8Disease Ontology, 9diseasecard, 48Orphanet, 62UMLS, 57SNOMED-CT, 46OMIM, 34MeSH, 39NCIt, 35MESH via Orphanet, 26ICD10 via Orphanet, 63UMLS via Orphanet
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Neurohypophyseal Diabetes Insipidus, Aliases & Descriptions:

Name: Neurohypophyseal Diabetes Insipidus 8 62
Central Diabetes Insipidus 8 48 62
Vasopressin Defective Diabetes Insipidus 8 62
Pituitary Diabetes Insipidus 8 62
Cdi 48 62
Hereditary Neurogenic Diabetes Insipidus 48
 
Hereditary Central Diabetes Insipidus 48
Diabetes Insipidus, Neurohypophyseal 9
Diabetes Insipidus, Neurogenic 62
Neurogenic Diabetes Insipidus 48
Vasopressin Deficiency 8
Hereditary Cdi 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Endocrine diseases, Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
central diabetes insipidus:
Inheritance: Autosomal dominant,Autosomal recessive,X-linked dominant; Prevalence: 1-9/100000; Age of onset: Childhood; Age of death: Normal
hereditary neurogenic diabetes insipidus:
Inheritance: Autosomal dominant,Autosomal recessive,X-linked dominant; Age of onset: Childhood; Age of death: Normal


External Ids:

Disease Ontology8 DOID:12388
MeSH34 D020790
NCIt39 C84933
MESH via Orphanet35 D020790
ICD10 via Orphanet26 E23.2
UMLS via Orphanet63 C0687720

Related Diseases for Neurohypophyseal Diabetes Insipidus

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Diseases related to Neurohypophyseal Diabetes Insipidus via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 102)
idRelated DiseaseScoreTop Affiliating Genes
1panhypopituitarism31.0POMC, AVP
2diabetes insipidus31.0AQP2, POMC, AVP, OXT, AVPR2
3nephrogenic diabetes insipidus30.8AVPR2, AQP2
4pituitary apoplexy30.8POMC
5hypopituitarism30.8AVP, POMC, AQP2
6neurogenic diabetes insipidus30.6OXT, AVPR2, AVP, POMC, AQP2
7craniopharyngioma30.3POMC, AVP
8hypothyroidism30.0OXT, POMC, AVP
9leukemia10.7
10germinoma10.6
11langerhans-cell histiocytosis10.6
12histiocytosis10.6
13lymphocytic hypophysitis10.6
14congenital toxoplasmosis10.5
15toxoplasmosis10.5
16acquired central diabetes insipidus10.5
17neuronitis10.5
18brain injury10.4
19traumatic brain injury10.4
20encephalitis10.4
21myeloid leukemia10.4
22neurosarcoidosis10.4
23nephrogenic syndrome of inappropriate antidiuresis10.4AVPR2
24endolymphatic hydrops10.3AQP2
25acute myeloid leukemia10.3
26b-cell lymphomas10.3
27diabetes mellitus10.3
28cerebritis10.3
29hypogonadism10.3
30optic atrophy10.3
31sarcoidosis10.3
32multifocal fibrosclerosis10.3
33gitelman syndrome10.3
34systemic lupus erythematosus10.2
35lung cancer10.2
36lupus erythematosus10.2
37acute lymphocytic leukemia10.2
38acute monocytic leukemia10.2
39arthritis10.2
40cerebellar ataxia10.2
41chronic myeloid leukemia10.2
42common variable immunodeficiency10.2
43juvenile myelomonocytic leukemia10.2
44malaria10.2
45megakaryocytic leukemia10.2
46myelodysplastic syndromes10.2
47obesity10.2
48rheumatoid arthritis10.2
49type 2 diabetes mellitus10.2
50down syndrome10.2

Graphical network of the top 20 diseases related to Neurohypophyseal Diabetes Insipidus:



Diseases related to neurohypophyseal diabetes insipidus

Symptoms for Neurohypophyseal Diabetes Insipidus

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Clinical features from OMIM:

125700,304900

Symptoms:

48 (show all 20)
  • pollakiuria/polyuria/dysuria/anuria/acute urine retention/oliguria
  • diabetes insipidus
  • autosomal dominant inheritance
  • autosomal recessive inheritance
  • x-linked dominant inheritance
  • weight loss/loss of appetite/break in weight curve/general health alteration
  • thirst
  • dehydration/hydroelectrolytic loss
  • facial pain/cephalalgia/migraine
  • somnolence/hypersomnia/parasomnia
  • obnubilation/coma/lethargia/desorientation
  • humour troubles/anxiety/depression/apathy/euphoria/irritability
  • failure to thrive/difficulties for feeding in infancy/growth delay
  • fever/chilling
  • nausea/vomiting/regurgitation/merycism/hyperemesis
  • acute diarrhea
  • seizures/epilepsy/absences/spasms/status epilepticus
  • hypernatremia
  • hyponatremia
  • malabsorption/chronic diarrhea/steatorrhea

HPO human phenotypes related to Neurohypophyseal Diabetes Insipidus:

(show all 21)
id Description Frequency HPO Source Accession
1 diabetes insipidus hallmark (90%) HP:0000873
2 weight loss hallmark (90%) HP:0001824
3 dehydration hallmark (90%) HP:0001944
4 abnormal renal physiology hallmark (90%) HP:0012211
5 diabetes insipidus hallmark (90%) HP:0000873
6 abnormal renal physiology hallmark (90%) HP:0012211
7 behavioral abnormality typical (50%) HP:0000708
8 migraine typical (50%) HP:0002076
9 abnormality of temperature regulation typical (50%) HP:0004370
10 reduced consciousness/confusion typical (50%) HP:0004372
11 behavioral abnormality typical (50%) HP:0000708
12 weight loss typical (50%) HP:0001824
13 nausea and vomiting typical (50%) HP:0002017
14 malabsorption typical (50%) HP:0002024
15 abnormality of temperature regulation typical (50%) HP:0004370
16 reduced consciousness/confusion typical (50%) HP:0004372
17 seizures occasional (7.5%) HP:0001250
18 diarrhea occasional (7.5%) HP:0002014
19 nausea and vomiting occasional (7.5%) HP:0002017
20 hyponatremia occasional (7.5%) HP:0002902
21 hypernatremia occasional (7.5%) HP:0003228

Drugs & Therapeutics for Neurohypophyseal Diabetes Insipidus

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Drug clinical trials:

Search ClinicalTrials for Neurohypophyseal Diabetes Insipidus

Search NIH Clinical Center for Neurohypophyseal Diabetes Insipidus

Genetic Tests for Neurohypophyseal Diabetes Insipidus

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Anatomical Context for Neurohypophyseal Diabetes Insipidus

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MalaCards organs/tissues related to Neurohypophyseal Diabetes Insipidus:

32
Pituitary, Testes

Animal Models for Neurohypophyseal Diabetes Insipidus or affiliated genes

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MGI Mouse Phenotypes related to Neurohypophyseal Diabetes Insipidus:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.3AVPR2, POMC, AQP2, OXT, NLRP3
2MP:00053788.2NLRP3, OXT, AQP2, POMC, AVPR2
3MP:00053678.0NLRP3, OXT, AQP2, POMC, AVP, AVPR2
4MP:00053767.8AVPR2, AVP, POMC, AQP2, OXT, NLRP3
5MP:00107687.7AVPR2, AVP, POMC, AQP2, OXT, NLRP3
6MP:00036317.6AVP, POMC, OXT, NLRP3, NPTX2
7MP:00053867.5AVPR2, AVP, POMC, AQP2, OXT, NPTX2

Publications for Neurohypophyseal Diabetes Insipidus

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Articles related to Neurohypophyseal Diabetes Insipidus:

(show top 50)    (show all 65)
idTitleAuthorsYear
1
Type III Bartter-like syndrome in an infant boy with Gitelman syndrome and autosomal dominant familial neurohypophyseal diabetes insipidus. (24825090)
2014
2
Dilatative Uropathy as a Manifestation of Neurohypophyseal Diabetes Insipidus due to a Novel Mutation in the Arginine Vasopressin-Neurophysin-II Gene. (24158882)
2013
3
A novel variation in the AVP gene resulting in familial neurohypophyseal diabetes insipidus in a large Italian kindred. (22695750)
2013
4
A novel deletion partly removing the AVP gene causes autosomal recessive inheritance of early-onset neurohypophyseal diabetes insipidus. (22168581)
2013
5
Clinical review: Treatment of neurohypophyseal diabetes insipidus. (23884783)
2013
6
Late-onset familial neurohypophyseal diabetes insipidus due to a novel mutation in the AVP gene. (22524462)
2012
7
Clinical and molecular analysis of a Chinese family with autosomal dominant neurohypophyseal diabetes insipidus associated with a novel missense mutation in the vasopressin-neurophysin II gene. (22307687)
2012
8
Familial neurohypophyseal diabetes insipidus due to a novel mutation in the arginine vasopressin-neurophysin II gene. (21498630)
2011
9
Growth retardation in untreated autosomal dominant familial neurohypophyseal diabetes insipidus caused by one recurring and two novel mutations in the vasopressin-neurophysin II gene. (21088058)
2011
10
Autosomal recessive familial neurohypophyseal diabetes insipidus: onset in early infancy. (19897608)
2010
11
Autosomal dominant neurohypophyseal diabetes insipidus in two families. Molecular analysis of the vasopressin-neurophysin II gene and functional studies of three missense mutations. (19129716)
2009
12
Autosomal dominant familial neurohypophyseal diabetes insipidus caused by a novel mutation in arginine-vasopressin gene in a Brazilian family. (19169480)
2008
13
Utility of AVP gene testing in familial neurohypophyseal diabetes insipidus. (18494865)
2008
14
A novel heterozygous missense mutation in the vasopressin moiety is identified in a Japanese person with neurohypophyseal diabetes insipidus. (16682840)
2006
15
Familial neurohypophyseal diabetes insipidus--an update. (16713494)
2006
16
Autophagy-dependent cell survival and cell death in an autosomal dominant familial neurohypophyseal diabetes insipidus in vitro model. (15781608)
2005
17
Expression of three different mutations in the arginine vasopressin gene suggests genotype-phenotype correlation in familial neurohypophyseal diabetes insipidus kindreds. (16060916)
2005
18
Autosomal dominant neurohypophyseal diabetes insipidus with linkage to chromosome 20p13 but without mutations in the AVP-NPII gene. (15811933)
2005
19
A novel splice site mutation of the arginine vasopressin-neurophysin II gene identified in a kindred with autosomal dominant familial neurohypophyseal diabetes insipidus. (16006166)
2005
20
Autophagy is a prosurvival mechanism in cells expressing an autosomal dominant familial neurohypophyseal diabetes insipidus mutant vasopressin transgene. (15781609)
2005
21
Differential cellular handling of defective arginine vasopressin (AVP) prohormones in cells expressing mutations of the AVP gene associated with autosomal dominant and recessive familial neurohypophyseal diabetes insipidus. (15356057)
2004
22
A novel mutation in the preprovasopressin gene identified in a kindred with autosomal dominant neurohypophyseal diabetes insipidus. (15070970)
2004
23
Six novel mutations in the arginine vasopressin gene in 15 kindreds with autosomal dominant familial neurohypophyseal diabetes insipidus give further insight into the pathogenesis. (14673472)
2004
24
Autosomal dominant familial neurohypophyseal diabetes insipidus. (12874957)
2003
25
Progressive decline of vasopressin secretion in familial autosomal dominant neurohypophyseal diabetes insipidus presenting a novel mutation in the vasopressin-neurophysin II gene. (14510916)
2003
26
Autosomal dominant neurohypophyseal diabetes insipidus due to substitution of histidine for tyrosine-2 in the vasopressin moiety of the hormone precursor. (12107248)
2002
27
Clinical and molecular analysis of three families with autosomal dominant neurohypophyseal diabetes insipidus associated with a novel and recurrent mutations in the vasopressin-neurophysin II gene. (11980620)
2002
28
A missense mutation encoding cys(67) --> gly in neurophysin ii is associated with early onset autosomal dominant neurohypophyseal diabetes insipidus. (11161827)
2001
29
A new mutation of the arginine vasopressin-neurophysin II gene in a family with autosomal dominant neurohypophyseal diabetes insipidus. (11748489)
2001
30
Familial neurohypophyseal diabetes insipidus associated with a novel mutation in the vasopressin-neurophysin II gene. (10677561)
2000
31
Identification of two distinct mutations at the same nucleotide position, concomitantly with a novel polymorphism in the vasopressin- neurophysin II gene (AVP-NP II) in two Dutch families with familial neurohypophyseal diabetes insipidus. (11017955)
2000
32
Endoplasmic reticulum derangement in hypothalamic neurons of rats expressing a familial neurohypophyseal diabetes insipidus mutant vasopressin transgene. (10973916)
2000
33
Molecular analysis in familial neurohypophyseal diabetes insipidus: early diagnosis of an asymptomatic carrier. (10487710)
1999
34
Clinical and molecular evidence of abnormal processing and trafficking of the vasopressin preprohormone in a large kindred with familial neurohypophyseal diabetes insipidus due to a signal peptide mutation. (10443701)
1999
35
A novel mutation (R97C) in the neurophysin moiety of prepro-vasopressin-neurophysin II associated with autosomal-dominant neurohypophyseal diabetes insipidus. (10329029)
1999
36
Autosomal recessive familial neurohypophyseal diabetes insipidus with continued secretion of mutant weakly active vasopressin. (10369876)
1999
37
Identification of a novel nonsense mutation and a missense substitution in the vasopressin-neurophysin II gene in two Spanish kindreds with familial neurohypophyseal diabetes insipidus. (9580132)
1998
38
Autosomal dominant neurohypophyseal diabetes insipidus associated with a missense mutation encoding Gly23-->Val in neurophysin II. (9360520)
1997
39
Heterogeneity in clinical manifestation of autosomal dominant neurohypophyseal diabetes insipidus caused by a mutation encoding Ala-1-->Val in the signal peptide of the arginine vasopressin/neurophysin II/copeptin precursor. (8989232)
1997
40
Magnetic resonance imaging of posterior pituitary for evaluation of the neurohypophyseal function in idiopathic and autosomal dominant neurohypophyseal diabetes insipidus. (9265683)
1997
41
Molecular basis of autosomal dominant neurohypophyseal diabetes insipidus. Cellular toxicity caused by the accumulation of mutant vasopressin precursors within the endoplasmic reticulum. (9109434)
1997
42
Genetic basis of familial neurohypophyseal diabetes insipidus. (18406826)
1997
43
A novel point mutation in the translation initiation codon of the pre-pro-vasopressin-neurophysin II gene: cosegregation with morphological abnormalities and clinical symptoms in autosomal dominant neurohypophyseal diabetes insipidus. (8550751)
1996
44
Recurrent mutations in the vasopressin-neurophysin II gene cause autosomal dominant neurohypophyseal diabetes insipidus. (8964872)
1996
45
A novel mutation in the coding region for neurophysin-II is associated with autosomal dominant neurohypophyseal diabetes insipidus. (8706292)
1996
46
A de novo mutation in the coding sequence for neurophysin-II (Pro24-->Leu) is associated with onset and transmission of autosomal dominant neurohypophyseal diabetes insipidus. (8045958)
1994
47
Familial neurohypophyseal diabetes insipidus associated with a signal peptide mutation. (8370682)
1993
48
A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus. (1740104)
1992
49
Molecular analysis of autosomal dominant neurohypophyseal diabetes insipidus. (1968469)
1990
50
A family with congenital hypothalamic neurohypophyseal diabetes insipidus. (5422994)
1970

Variations for Neurohypophyseal Diabetes Insipidus

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Clinvar genetic disease variations for Neurohypophyseal Diabetes Insipidus:

6 (show all 18)
id Gene Name Type Significance SNP ID Assembly Location
1AVPNM_000490.4(AVP): c.262G> A (p.Gly88Ser)single nucleotide variantPathogenicrs121964882GRCh37Chr 20, 3063683: 3063683
2AVPNM_000490.4(AVP): c.143G> T (p.Gly48Val)single nucleotide variantPathogenicrs121964883GRCh37Chr 20, 3063802: 3063802
3AVPNM_000490.4(AVP): c.55G> A (p.Ala19Thr)single nucleotide variantPathogenicrs387906511GRCh37Chr 20, 3065266: 3065266
4AVPAVP, 3-BP DEL, NT1824deletionPathogenic
5AVPNM_000490.4(AVP): c.294C> A (p.Cys98Ter)single nucleotide variantPathogenicrs121964884GRCh37Chr 20, 3063651: 3063651
6AVPNM_000490.4(AVP): c.277G> T (p.Gly93Trp)single nucleotide variantPathogenicrs121964885GRCh37Chr 20, 3063668: 3063668
7AVPAVP, 1-BP DEL, 227GdeletionPathogenic
8AVPNM_000490.4(AVP): c.287G> T (p.Gly96Val)single nucleotide variantPathogenicrs121964886GRCh37Chr 20, 3063658: 3063658
9AVPNM_000490.4(AVP): c.56C> T (p.Ala19Val)single nucleotide variantPathogenicrs387906512GRCh37Chr 20, 3065265: 3065265
10AVPNM_000490.4(AVP): c.161G> T (p.Gly54Val)single nucleotide variantPathogenicrs121964887GRCh37Chr 20, 3063784: 3063784
11AVPNM_000490.4(AVP): c.160G> C (p.Gly54Arg)single nucleotide variantPathogenicrs121964888GRCh37Chr 20, 3063785: 3063785
12AVPNM_000490.4(AVP): c.337G> T (p.Glu113Ter)single nucleotide variantPathogenicrs121964889GRCh37Chr 20, 3063434: 3063434
13AVPNM_000490.4(AVP): c.260C> T (p.Ser87Phe)single nucleotide variantPathogenicrs121964890GRCh37Chr 20, 3063685: 3063685
14AVPNM_000490.4(AVP): c.275G> A (p.Cys92Tyr)single nucleotide variantPathogenicrs121964891GRCh37Chr 20, 3063670: 3063670
15AVPNM_000490.4(AVP): c.200T> C (p.Val67Ala)single nucleotide variantPathogenicrs28934878GRCh37Chr 20, 3063745: 3063745
16AVPNM_000490.4(AVP): c.346T> G (p.Cys116Gly)single nucleotide variantPathogenicrs74315383GRCh37Chr 20, 3063425: 3063425
17AVPNM_000490.4(AVP): c.61T> C (p.Tyr21His)single nucleotide variantPathogenicrs121964893GRCh37Chr 20, 3065260: 3065260
18AVPAVP, 3-BP DEL, PHE3DELdeletionPathogenic

Expression for genes affiliated with Neurohypophyseal Diabetes Insipidus

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Expression patterns in normal tissues for genes affiliated with Neurohypophyseal Diabetes Insipidus

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Pathways for genes affiliated with Neurohypophyseal Diabetes Insipidus

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Pathways related to Neurohypophyseal Diabetes Insipidus according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3AQP2, AVP, AVPR2
2
Show member pathways
9.3AVPR2, AVP, AQP2
3
Show member pathways
9.3AQP2, AVP, AVPR2
49.2POMC, AVP, AVPR2
5
Show member pathways
8.7OXT, POMC, AVP, AVPR2
6
Show member pathways
8.7AVPR2, AVP, POMC, OXT

Compounds for genes affiliated with Neurohypophyseal Diabetes Insipidus

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Compounds related to Neurohypophyseal Diabetes Insipidus according to GeneCards/GeneDecks:

(show all 43)
idCompoundScoreTop Affiliating Genes
1atosiban44 2811.0OXT, AVPR2
2oxytocin61 28 24 1113.0OXT, AVPR2
3ether44 5011.0POMC, AVP
4furosemide44 61 28 50 24 1114.8AQP2, POMC
5ipsapirone44 2810.8OXT, POMC
6allopregnanolone449.8POMC, OXT
7melatonin44 28 61 24 1113.8AVP, OXT
8hexarelin44 2810.8OXT, POMC
9pge1449.8OXT, AVPR2
10d[leu4,lys8]-vp619.8AVPR2, AVP, NLRP3
11(d(ch2)51,tyr(me)2,arg8)-vasopressin619.8AVPR2, AVP, NLRP3
12[arg8]-vasopressin619.8AVPR2, AVP, NLRP3
13sr 4905961 2810.8AVPR2, AVP, NLRP3
14naloxone44 28 50 1112.8POMC, OXT
15diazepam44 28 50 1112.8OXT, POMC
16opiate449.7OXT, POMC
17phenylephrine44 28 24 1112.7POMC, OXT
18chloride449.7AVPR2, AVP, AQP2
19progestin449.6OXT, POMC
20sodium44 2410.6AVPR2, AVP, AQP2
21corticosterone44 61 2411.5OXT, POMC
22catecholamine449.5AVP, POMC
23haloperidol44 50 28 2 1113.5AQP2, POMC
24mifepristone44 28 61 1112.5OXT, POMC
25hydrocortisone44 2 61 1112.5AQP2, POMC
26norepinephrine44 24 1111.4OXT, POMC, AVP
27adenylate449.4AQP2, POMC, AVPR2
28aspartate449.4OXT, POMC, AVPR2
29epinephrine44 24 1111.3OXT, AQP2, POMC
30forskolin44 50 1111.3OXT, AQP2, POMC
31pge2449.3OXT, AQP2, POMC
32alanine449.2AVPR2, AVP, POMC, AQP2
33cysteine449.1AVPR2, AVP, AQP2, OXT
34acth449.1OXT, POMC, AVP, AVPR2
35progesterone44 28 61 24 1113.1POMC, AQP2, OXT
36creatinine449.0AVP, POMC, AQP2, OXT
37steroid449.0OXT, AQP2, POMC, AVP
38dexamethasone44 50 28 1111.9AQP2, POMC, AVP
39serine448.8OXT, AQP2, POMC, AVP
40glutamate448.8NPTX2, OXT, AVP, AVPR2
41arginine448.7AVPR2, AVP, POMC, AQP2, OXT
42calcium44 50 24 1111.3AVPR2, AVP, AQP2, OXT, NPTX2
43desmopressin44 61 28 1111.3NLRP3, AVPR2, AVP, POMC, AQP2, OXT

GO Terms for genes affiliated with Neurohypophyseal Diabetes Insipidus

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Cellular components related to Neurohypophyseal Diabetes Insipidus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301418.8OXT, POMC, AVP
2extracellular regionGO:0055768.3NPTX2, OXT, POMC, AVP

Biological processes related to Neurohypophyseal Diabetes Insipidus according to GeneCards/GeneDecks:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of systemic arterial blood pressureGO:00308410.0AVP, AVPR2
2maternal aggressive behaviorGO:0021259.9OXT, AVP
3hyperosmotic salinity responseGO:0425389.9AVP, OXT
4negative regulation of urine volumeGO:0358119.8AVPR2, OXT
5maternal behaviorGO:0427119.8AVP, OXT
6grooming behaviorGO:0076259.8OXT, AVP
7social behaviorGO:0351769.7OXT, AVP
8excretionGO:0075889.7AQP2, AVPR2
9generation of precursor metabolites and energyGO:0060919.6AVP, POMC
10positive regulation of cytosolic calcium ion concentrationGO:0072049.6OXT, AVP
11water transportGO:0068339.6AQP2, AVP, AVPR2
12female pregnancyGO:0075659.4OXT, AQP2
13transmembrane transportGO:0550859.0AQP2, AVP, AVPR2
14signal transductionGO:0071658.8AVP, POMC, OXT, NLRP3

Molecular functions related to Neurohypophyseal Diabetes Insipidus according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1neurohypophyseal hormone activityGO:0051859.6OXT, AVP

Products for genes affiliated with Neurohypophyseal Diabetes Insipidus

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  • Antibodies
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Sources for Neurohypophyseal Diabetes Insipidus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet