MCID: NRM004
MIFTS: 48

Neuroma malady

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Neuroma

Aliases & Descriptions for Neuroma:

Name: Neuroma 12 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2001
MeSH 42 D009463
NCIt 47 C3275
UMLS 69 C0027858

Summaries for Neuroma

Disease Ontology : 12 A nervous system benign neoplasm that is characterized as a nerve tissue tumor.

MalaCards based summary : Neuroma is related to aneurysm and breast reconstruction. An important gene associated with Neuroma is ANK3 (Ankyrin 3), and among its related pathways/superpathways are Developmental Biology and Neuroscience. The drugs Bupivacaine and Mepivacaine have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and skin, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 71 A neuroma /njuːˈroʊmə/ (plural: neuromata or neuromas) is a growth or tumor of nerve tissue.... more...

Related Diseases for Neuroma

Diseases related to Neuroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 176)
id Related Disease Score Top Affiliating Genes
1 aneurysm 29.7 CALCA GDNF RET
2 breast reconstruction 29.5 ENO2 GFAP S100B
3 pheochromocytoma 29.3 CALCA ENO2 GDNF NGF RET
4 acoustic neuroma 12.4
5 multiple mucosal neuroma 12.0
6 neuroma biliary tract 11.8
7 neurofibromatosis 11.7
8 multiple endocrine neoplasia iib 11.6
9 neurofibromatosis, type 2 11.2
10 klumpke paralysis 10.9
11 neurofibromatosis, type 1 10.8
12 erb-duchenne and dejerine-klumpke palsies 10.8
13 uterine corpus sarcoma 10.3 ENO2 RET
14 cavernous hemangioma of colon 10.3 ENO2 NF2
15 bronchitis 10.3 GFAP NF2
16 benign schwannoma 10.3 ENO2 S100B
17 meigel disease 10.3 GDNF RET
18 pediatric cns embryonal cell carcinoma 10.3 GFAP NF2
19 thrombophlebitis 10.2 ENO2 GFAP
20 jejunal somatostatinoma 10.2 ENO2 GFAP NF2
21 porokeratosis 10.2 GFAP NF2 S100B
22 pathologic nystagmus 10.2 ANK3 NF2 S100B
23 aneurysm of sinus of valsalva 10.2 GFAP NF2 S100B
24 bronchial mucus gland adenoma 10.2 GFAP S100B
25 behcet's syndrome arthropathy 10.2 GFAP PCNA S100B
26 breast squamous cell carcinoma 10.2 ENO2 GFAP NF2
27 hypermobility of coccyx 10.2 NGF SCN10A
28 myelinoclastic diffuse sclerosis 10.2 ENO2 GFAP S100B
29 external ear disease 10.2 GFAP NF2
30 piussan lenaerts mathieu syndrome 10.2 ENO2 GFAP S100B
31 skin glomus tumor 10.2 ENO2 GFAP S100B
32 pediculus humanus corporis infestation 10.2 ENO2 GFAP S100B
33 c-p angle neurinoma 10.2 GFAP NF2 S100B
34 hypoparathyroidism-intellectual disability-dysmorphism syndrome 10.2 GDNF RET S100B
35 central nervous system hemangioma 10.2 ENO2 GFAP S100B
36 blood group incompatibility 10.2 ENO2 GFAP NGF
37 granular cell leiomyosarcoma 10.2 ENO2 GFAP S100B
38 postmenopausal atrophic vaginitis 10.2 ENO2 NF2 NGF
39 upper respiratory tract disease 10.2 FGF2 GFAP TGFB1
40 thoracic outlet syndrome 10.1 ENO2 NF2 NGF
41 adult oligodendroglioma 10.1 ENO2 GFAP PCNA
42 spleen angiosarcoma 10.1 GFAP S100B
43 albinism, oculocutaneous, type ia 10.1 FGF2 GFAP TGFB1
44 epimetaphyseal dysplasia cataract 10.1 ENO2 GFAP NF2 S100B
45 cartilage disease 10.1 CALCA TGFB1
46 flat ductal epithelial atypia 10.1 ENO2 FGF2 GFAP
47 orofaciodigital syndrome iv 10.1 GFAP NF2 PCNA S100B
48 malignant visceral pleura tumor 10.1 CALCA NGF
49 juvenile astrocytoma 10.1 ENO2 GFAP S100B
50 hirschsprung disease 1 10.1 CALCA GDNF RET

Graphical network of the top 20 diseases related to Neuroma:



Diseases related to Neuroma

Symptoms & Phenotypes for Neuroma

MGI Mouse Phenotypes related to Neuroma:

44 (show all 11)
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.34 SCN10A SEMA3F TGFB1 TRPV1 ANK3 AQP4
2 growth/size/body region MP:0005378 10.23 AQP4 ENO2 FGFR4 GDNF GFAP NF2
3 homeostasis/metabolism MP:0005376 10.21 AQP4 FGF2 FGFR4 GFAP NF2 NGF
4 mortality/aging MP:0010768 10.18 PCNA RET SEMA3F TGFB1 ANK3 AQP4
5 cardiovascular system MP:0005385 10.13 AQP4 FGF2 GDNF GFAP NGF RET
6 nervous system MP:0003631 10.13 ANK3 AQP4 ENO2 FGF2 GDNF GFAP
7 neoplasm MP:0002006 9.85 FGFR4 NF2 RET TGFB1 TRPV1 FGF2
8 no phenotypic analysis MP:0003012 9.8 ANK3 AQP4 NGF PCNA RET SCN10A
9 renal/urinary system MP:0005367 9.7 ANK3 AQP4 GDNF NF2 RET TGFB1
10 respiratory system MP:0005388 9.56 ANK3 AQP4 ENO2 FGFR4 NF2 RET
11 vision/eye MP:0005391 9.17 AQP4 FGF2 GFAP NF2 NGF SEMA3F

Drugs & Therapeutics for Neuroma

Drugs for Neuroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 143)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
2
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4 Anesthetics Phase 4,Phase 1,Early Phase 1
5 Anesthetics, Local Phase 4,Phase 1,Early Phase 1
6 Central Nervous System Depressants Phase 4,Phase 2,Phase 1,Early Phase 1
7 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Early Phase 1
8 Anti-Inflammatory Agents Phase 4,Phase 2
9 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
10 Anti-Infective Agents Phase 4,Phase 2,Phase 1,Early Phase 1
11 Immunosuppressive Agents Phase 4,Phase 2,Phase 1,Early Phase 1
12 Gentamicins Phase 4
13 glucocorticoids Phase 4
14 Hormone Antagonists Phase 4
15 Hormones Phase 4
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
17 triamcinolone acetonide Phase 4
18 Triamcinolone diacetate Phase 4
19 Triamcinolone hexacetonide Phase 4
20 Anticholesteremic Agents Phase 4
21 Antimetabolites Phase 4,Phase 2,Phase 1
22 Chelating Agents Phase 4
23 Coagulants Phase 4
24 Hemostatics Phase 4
25 Hypolipidemic Agents Phase 4
26 Lipid Regulating Agents Phase 4
27
Chitosan Nutraceutical Phase 4 9012-76-4 71853
28
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
29
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
30
Mechlorethamine Approved Phase 3,Phase 2 51-75-2 4033
31
Cyclophosphamide Approved, Investigational Phase 2, Phase 3 50-18-0, 6055-19-2 2907
32
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
33 Alkylating Agents Phase 3,Phase 2,Phase 1
34 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1,Early Phase 1
35 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
36 Isophosphamide mustard Phase 3,Phase 2
37 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
38 Protein Kinase Inhibitors Phase 2, Phase 3,Early Phase 1
39 Imatinib Mesylate Phase 2, Phase 3 123596
40
Acetylcholine Approved Phase 2 51-84-3 187
41
Capsaicin Approved Phase 2,Phase 1 404-86-4 1548943
42
Bevacizumab Approved, Investigational Phase 2,Phase 1 216974-75-3
43
Mexiletine Approved Phase 2 31828-71-4 4178
44
Morphine Approved, Investigational Phase 2 57-27-2 5288826
45
Everolimus Approved Phase 2,Phase 1,Early Phase 1 159351-69-6 6442177
46
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
47
Sirolimus Approved, Investigational Phase 2,Phase 1,Early Phase 1 53123-88-9 5284616 6436030 46835353
48
Dacarbazine Approved, Investigational Phase 2,Phase 1 4342-03-4 5351166
49
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
50
Etoposide Approved Phase 2 33419-42-0 36462

Interventional clinical trials:

(show top 50) (show all 115)
id Name Status NCT ID Phase
1 Pathophysiology of Post Amputation Pain Completed NCT01632709 Phase 4
2 A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options Completed NCT00948025 Phase 4
3 Blind and Ultrasound Guided Injection in Morton Neuroma Recruiting NCT03046108 Phase 4
4 Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function Recruiting NCT02415257 Phase 4
5 Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function Recruiting NCT02379754 Phase 4
6 Chitosan Nerv Tube for Primary Repair of Traumatic Sensory Nerve Lesions of the Hand Recruiting NCT02372669 Phase 4
7 Stereotactic Radiation in Vestibular Schwannoma Unknown status NCT01449604 Phase 3
8 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Unknown status NCT00346164 Phase 3
9 Cyberknife Radiosurgery for Patients With Neurinomas Recruiting NCT02055859 Phase 3
10 Vestibular Schwannoma - Radiosurgery or Expectation: V-REX. Recruiting NCT02249572 Phase 2, Phase 3
11 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3
12 Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors Terminated NCT00427583 Phase 2, Phase 3
13 ALGRX 4975 in the Treatment of Patients With Morton's Neuroma Completed NCT00130962 Phase 2
14 A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02283957 Phase 2
15 An Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02678793 Phase 2
16 Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2) Completed NCT01207687 Phase 2
17 Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT00973739 Phase 2
18 Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2 Completed NCT00004437 Phase 2
19 Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain Completed NCT00383682 Phase 2
20 Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT02104323 Phase 2
21 Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients Completed NCT01490476 Phase 2
22 Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2 Completed NCT01419639 Phase 2
23 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2
24 Sorafenib and Dacarbazine in Soft Tissue Sarcoma Completed NCT00837148 Phase 2
25 Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors Completed NCT00304083 Phase 2
26 S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor Completed NCT00068367 Phase 2
27 Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular Schwannoma Recruiting NCT01199978 Phase 2
28 Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma Recruiting NCT01345136 Phase 2
29 Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Recruiting NCT02934256 Phase 2
30 Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas Recruiting NCT02129647 Phase 2
31 Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors Recruiting NCT03095248 Phase 2
32 AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas Recruiting NCT02831257 Phase 2
33 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
34 A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery Recruiting NCT02691026 Phase 2
35 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Recruiting NCT02601209 Phase 1, Phase 2
36 PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors Recruiting NCT02584647 Phase 1, Phase 2
37 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2
38 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2
39 Axillary Reverse Mapping Active, not recruiting NCT00572481 Phase 2
40 Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas Active, not recruiting NCT01767792 Phase 2
41 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Active, not recruiting NCT01125046 Phase 2
42 Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma Active, not recruiting NCT02452554 Phase 2
43 SARC023: Ganetespib and Sirolimos in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) Active, not recruiting NCT02008877 Phase 1, Phase 2
44 SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors Active, not recruiting NCT01661283 Phase 2
45 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Active, not recruiting NCT01653028 Phase 2
46 Trial of Dasatinib in Advanced Sarcomas Active, not recruiting NCT00464620 Phase 2
47 Study of Aspirin in Patients With Vestibular Schwannoma Not yet recruiting NCT03079999 Phase 2
48 Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors Not yet recruiting NCT02986919 Phase 2
49 PTC299 for Treatment of Neurofibromatosis Type 2 Suspended NCT00911248 Phase 2
50 A Study of Nilotinib in Growing Vestibular Schwannomas Terminated NCT01201538 Phase 2

Search NIH Clinical Center for Neuroma

Cochrane evidence based reviews: neuroma

Genetic Tests for Neuroma

Anatomical Context for Neuroma

MalaCards organs/tissues related to Neuroma:

39
Bone, Brain, Skin, Breast, Testes, Tongue, Appendix

Publications for Neuroma

Articles related to Neuroma:

(show top 50) (show all 984)
id Title Authors Year
1
Reexcision Perineural Invasion and Epithelial Sheath Neuroma Possibly on a Spectrum of Postinjury Reactive Hyperplasia Mediated by IL-6. ( 27749287 )
2017
2
Homogeneous white patch in dermoscopy of solitary circumscribed neuroma. ( 28087044 )
2017
3
Regarding: Traumatic Neuroma After Hysterectomy. A Rare Cause of Posthysterectomy Pelvic Pain. ( 27818265 )
2017
4
Peripheral Neuromodulation for the Treatment of Postamputation Neuroma Pain: A Case Report. ( 27828784 )
2017
5
Ultrasound Evaluation of Morton Neuroma Before and After Laser Therapy. ( 27897032 )
2017
6
Traumatic Neuroma After Hysterectomy and Bilateral Salpingo-Oophorectomy: A Rare Cause of Post Hysterectomy Pelvic Pain. ( 27423258 )
2016
7
Acoustic neuroma as first sign of inner ear functional disorders. ( 27935543 )
2016
8
Neuroma of the distal posterior interosseous nerve as a cause of persistent dorsal wrist pain. ( 27939442 )
2016
9
Percutaneous MR-Guided Cryoablation of Morton's Neuroma: Rationale and Technical Details After the First 20 Patients. ( 27189181 )
2016
10
Evolution of Patients With Immediate Complete Facial Paralysis Secondary to Acoustic Neuroma Surgery. ( 26719351 )
2016
11
Histopathological Characterization of Tail Injury and Traumatic Neuroma Development after Tail Docking in Piglets. ( 27302763 )
2016
12
Reply: Hirano-Ali et al. (2016) reports a case of epithelial sheath neuroma. ( 27585072 )
2016
13
Traumatic neuroma on the digital tip: Immunohistochemical analysis of inflammatory signaling pathways. ( 26876467 )
2016
14
Suspected Acoustic Neuroma Demyelinating Lesions. ( 28005807 )
2016
15
SOS1 frameshift mutations cause pure mucosal neuroma syndrome, a clinical phenotype distinct from multiple endocrine neoplasia type 2B. ( 26708403 )
2016
16
Isolated Nonsyndromic Intraneural Neuroma of the Eyelid Skin. ( 27828924 )
2016
17
Traumatic neuroma of the superficial peroneal nerve in a patient: a case report and review of the literature. ( 27613606 )
2016
18
Radiographic Analysis of Feet With and Without Morton's Neuroma. ( 27837053 )
2016
19
Nonneoplastic Neuroma After Radical Prostatectomy Is Not a Mimicker of Lymph Node Metastases on 68Ga-PSMA Ligand PET/CT. ( 27556791 )
2016
20
The Fully Endoscopic Acoustic Neuroma Surgery. ( 27565388 )
2016
21
Extracorporeal Shockwave Therapy in Patients with Morton's Neuroma A Randomized, Placebo-Controlled Trial. ( 27031544 )
2016
22
Painful pediatric traumatic neuroma: surgical management and clinical outcomes. ( 27179535 )
2016
23
Epithelial sheath neuroma: hyperplasia or neoplasia? ( 27583714 )
2016
24
Traumatic Neuroma at the Inferior Mesenteric Artery Stump after Rectal Cancer Surgery: A Case Report and Literature Review. ( 27871166 )
2016
25
Palisaded Encapsulated Neuroma in a Zosteriform Distribution. ( 26955159 )
2016
26
A diffuse traumatic neuroma in the palate: a case report. ( 27165640 )
2016
27
Palisaded Encapsulated Neuroma of the Trunk: A Case Report and Review of Palisaded Encapsulated Neuroma. ( 27630799 )
2016
28
SU-F-T-611: Critical Analysis and Efficacy of Linac Based (Beam Modulator) and Cyberknife Treatment Plans for Acoustic Neuroma/schwannoma. ( 28047111 )
2016
29
Neuroma of the bile duct mimicking cholangiocarcinoma. ( 27329091 )
2016
30
Percutaneous alcohol injection under sonographic guidance in Morton's neuroma: follow-up in 220 treated lesions. ( 26883232 )
2016
31
Acoustic Neuroma Mimicking Orofacial Pain: A Unique Case Report. ( 28053796 )
2016
32
Diagnostic Value of Elastography in the Diagnosis of Intermetatarsal Neuroma. ( 26964696 )
2016
33
Solitary circumscribed neuroma of the palpebral conjunctiva: A rare location. ( 27522960 )
2016
34
Neurectomy Outcomes in Patients With Morton Neuroma: Comparison of Plantar vs Dorsal Approaches. ( 27999504 )
2016
35
Long-Term Results of Neurectomy Through a Dorsal Approach in the Treatment of Morton's Neuroma. ( 27627563 )
2016
36
Unusual case of traumatic neuroma of the orbit. ( 26891178 )
2016
37
The Persistence of Tinnitus after Acoustic Neuroma Surgery. ( 27095048 )
2016
38
In vivo visualization of the facial nerve in patients with acoustic neuroma using diffusion tensor imaging-based fiber tracking. ( 26722859 )
2016
39
The relationship between foot posture index, ankle equinus, body mass index and intermetatarsal neuroma. ( 27980684 )
2016
40
Ultrasound-Guided Cryoablation of a Traumatic Hip Disarticulation Neuroma. ( 28035780 )
2016
41
Risk Factors of Acoustic Neuroma: Systematic Review and Meta-Analysis. ( 26996581 )
2016
42
Change in tinnitus after acoustic neuroma removal using a translabyrinthine approach. A Prospective study. ( 27067182 )
2016
43
Surgical treatment of acoustic neuroma: Outcomes and indications. ( 27330426 )
2016
44
Treatment of a Recurrent Neuroma Within Nerve Allograft With Autologous Nerve Reconstruction. ( 27390572 )
2016
45
Successful Treatment of Foot and Ankle Neuroma Pain With Processed Nerve Allografts. ( 27340257 )
2016
46
Prevention of Painful Neuroma and Phantom Limb Pain After Transfemoral Amputations Through Concomitant Nerve Coaptation and Collagen Nerve Wrapping. ( 27306717 )
2016
47
Giant Glomus Tumor and Neuroma in the Fifth Ray A Case Report. ( 27031555 )
2016
48
Interdigital Neuroma in the Second Intermetatarsal Space Associated with Metatarsophalangeal Joint Instability. ( 28003923 )
2016
49
Is Histopathological Analysis of Interdigital Morton's Neuroma Necessary? ( 28030965 )
2016
50
Dorsal displacement of the facial nerve in acoustic neuroma surgery: clinical features and surgical outcomes of 21 consecutive dorsal pattern cases. ( 26621676 )
2016

Variations for Neuroma

Expression for Neuroma

Search GEO for disease gene expression data for Neuroma.

Pathways for Neuroma

Pathways related to Neuroma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.16 ANK3 FGF2 FGFR4 GDNF RET SCN10A
2 12.07 CALCA ENO2 GFAP NF2 NGF RET
3 11.54 AQP4 GDNF GFAP TGFB1
4 11.44 FGF2 FGFR4 TGFB1
5 11.36 FGF2 FGFR4 NGF TGFB1
6 11.23 CALCA FGF2 TGFB1
7 11 FGF2 FGFR4 GDNF GFAP NGF S100B

GO Terms for Neuroma

Cellular components related to Neuroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.46 ANK3 CALCA NF2 TRPV1
2 axon GO:0030424 9.26 ANK3 CALCA RET TGFB1
3 neuronal cell body GO:0043025 9.1 CALCA ENO2 RET S100B TGFB1 TRPV1

Biological processes related to Neuroma according to GeneCards Suite gene sharing:

(show all 15)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of apoptotic process GO:0043065 9.83 NGF S100B TGFB1 TRPV1
2 positive regulation of cell proliferation GO:0008284 9.72 FGF2 FGFR4 GDNF S100B TGFB1
3 phosphatidylinositol-mediated signaling GO:0048015 9.69 FGF2 FGFR4 NGF
4 negative regulation of DNA replication GO:0008156 9.55 NF2 TGFB1
5 positive regulation of gene expression GO:0010628 9.55 ANK3 FGFR4 NGF RET TGFB1
6 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.54 GDNF TGFB1
7 hyaluronan catabolic process GO:0030214 9.49 FGF2 TGFB1
8 negative regulation of blood vessel endothelial cell migration GO:0043537 9.48 FGF2 TGFB1
9 negative regulation of cell-cell adhesion GO:0022408 9.46 NF2 TGFB1
10 detection of temperature stimulus involved in sensory perception of pain GO:0050965 9.43 CALCA TRPV1
11 ureteric bud development GO:0001657 9.43 GDNF RET TGFB1
12 lens fiber cell differentiation GO:0070306 9.4 NF2 TGFB1
13 enteric nervous system development GO:0048484 9.37 GDNF RET
14 MAPK cascade GO:0000165 9.35 FGF2 FGFR4 GDNF RET TGFB1
15 response to pain GO:0048265 8.8 CALCA RET TRPV1

Molecular functions related to Neuroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 FGF2 GDNF NGF TGFB1
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.92 FGF2 FGFR4 GDNF RET

Sources for Neuroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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