MCID: NRM004
MIFTS: 47

Neuroma malady

Neuronal diseases, Cancer diseases categories

Summaries for Neuroma

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66Wikipedia, 34MalaCards
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Wikipedia:66 A neuroma /nju??ro?m?/ (plural: neuromata or neuromas) is a growth or tumor of nerve tissue. Neuromas... more...

MalaCards: Neuroma, also known as neuroma nos, is related to acoustic neuroma and multiple endocrine neoplasia. An important gene associated with Neuroma is NF2 (neurofibromin 2 (merlin)). The compound potassium have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and breast, and related mouse phenotypes are craniofacial and renal/urinary system.

Aliases & Classifications for Neuroma

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9Disease Ontology, 46Novoseek, 63UMLS, 59SNOMED-CT, 41NCIt, 36MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Aliases & Descriptions:

neuroma 9 46 63
neuroma nos 9


External Ids:

Disease Ontology9 DOID:2001
NCIt41 C3275
MeSH36 D009463

Related Diseases for Neuroma

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Neuroma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1acoustic neuroma31.8NF2, VHL, ABCA2, GDNF
2multiple endocrine neoplasia30.7GDNF, VHL, NF2
3neurofibromatosis30.6NF2, VHL
4glioblastoma multiforme30.0GDNF, AQP4, VHL
5breast cancer29.8LIG4, XRCC2, VHL, NF2
6multiple mucosal neuroma10.4
7cerebrospinal fluid leak10.4
8headache10.4
9meningioma10.3
10blindness10.3
11cervicitis10.2
12meningitis10.2
13wagenmann-froboese syndrome10.2
14facial paralysis10.2
15hydrocephalus10.2
16laryngitis10.2
17neurofibroma10.2
18fibroma10.1
19sensorineural hearing loss10.1
20arachnoiditis10.1
21pheochromocytoma10.1
22aneurysm10.1
23ramsay-hunt syndrome10.1
24multiple endocrine neoplasia type 2a10.1VHL, GDNF
25polycystic kidney disease10.1VHL, GDNF
26thyroid medullary carcinoma10.1VHL, GDNF
27burns10.0
28otosclerosis10.0
29geniculate ganglionitis10.0
30hemangioma10.0
31herpes simplex10.0
32neurilemmoma10.0
33pancreatitis10.0
34sarcoma10.0
35thyroiditis10.0
36neuroma biliary tract10.0
37temporal lobe epilepsy10.0GDNF, AQP4
38duchenne muscular dystrophy10.0AQP4, GDNF
39stroke, ischemic10.0AQP4, GDNF
40ovarian cancer10.0ABCA2, VHL, NF2
41glaucoma10.0AQP4, GDNF
42familial adenomatous polyposis10.0VHL, MUTYH
43brain cancer10.0NF2, AQP4, GDNF
44adenoma10.0GDNF, MUTYH, VHL
45ischemia10.0NF2, AQP4, GDNF
46astrocytoma9.9NF2, VHL, AQP4, GDNF
47malignant glioma9.9GDNF, AQP4, VHL, NF2
48ipex syndrome9.9AQP4, LIG4, NF2
49breast reconstruction9.9
50crohn's disease9.9

Graphical network of the top 20 diseases related to Neuroma:



Diseases related to neuroma

Symptoms for Neuroma

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Drugs & Therapeutics for Neuroma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Neuroma

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Anatomical Context for Neuroma

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Sources:
34MalaCards
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MalaCards organs/tissues related to Neuroma:

34
Bone, Brain, Breast, Testes, Skin, Tongue, Thyroid, Appendix, B cells, Temporal lobe, Eye, Lung, Liver, Colon, Spinal cord, Pituitary

Animal Models for Neuroma or affiliated genes

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Sources:
38MGI
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Publications for Neuroma

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Sources:
53PubMed
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Articles related to Neuroma:

(show top 50)    (show all 837)
idTitleAuthorsYear
1
Retrosigmoid craniotomy for resection of acoustic neuroma with hearing preservation: a video publication. (24380523)
2014
2
Colonic schistosomiasis and associated cecal neuroma. (23923251)
2013
3
Case of palisaded encapsulated neuroma involving the palm. (23110344)
2013
4
The case of acoustic neuroma: Comment on: Mobile phone use and risk of brain neoplasms and other cancers. (24078153)
2013
5
A case of gastric cancer manifesting as a solitary brain metastasis in the cerebellopontine angle that mimicked acoustic neuroma. (24400217)
2013
6
Regenerative surgery of the complications with Morton's neuroma surgery: use of platelet rich plasma and hyaluronic acid. (22694086)
2013
7
Traumatic neuroma in a patient with breast cancer after mastectomy: a case report and review of the literature. (22330690)
2012
8
The expression of I+-SMA in the painful traumatic neuroma: potential role in the pathobiology of neuropathic pain. (23020218)
2012
9
Recurrent nasopharyngeal carcinoma masquerading as acoustic neuroma. (22434308)
2012
10
Acoustic neuroma surgery for preservation of hearing: technique and experience in the Chinese PLA General Hospital. (20406132)
2010
11
Acoustic neuroma identified after electroconvulsive therapy in a patient with recurrent major depression and undifferentiated somatoform disorder. (20357670)
2010
12
Postoperative MR imaging of the foot and ankle: tendon repair, ligament repair, and Morton's neuroma resection. (20539960)
2010
13
Morton neuroma: MR imaging after resection--postoperative MR and histologic findings in asymptomatic and symptomatic intermetatarsal spaces. (20501722)
2010
14
Oral traumatic neuroma with mature ganglion cells: A case report and review of the literature. (21887004)
2009
15
Diagnosis and treatment of forefoot disorders. Section 3. Morton's intermetatarsal neuroma. (19232980)
2009
16
Neuroma of a double gallbladder: a case report. (19126190)
2009
17
Future perspectives in acoustic neuroma management. (18810226)
2008
18
Sonographically guided phenol instillation of stump neuroma. (18941058)
2008
19
Bridging critical nerve defects through an acellular homograft seeded with autologous schwann cells obtained from a regeneration neuroma of the proximal stump. (18438750)
2008
20
Morton neuroma: primary and secondary neurectomy. (18768712)
2008
21
Management of unilateral vestibular schwannoma/acoustic neuroma. (18264185)
2007
22
The potential role of nerve growth factor (NGF) in painful neuromas and the mechanism of pain relief by their relocation to muscle. (16928414)
2006
23
Conservative management of acoustic neuroma. (17077873)
2006
24
Endoscopic assisted microneurosurgery for gasserian portion of trigeminal neuroma: two cases. (17119812)
2006
25
Counseling patients on surgical options for treating acoustic neuroma. (16005723)
2005
26
Local phenol injection in the treatment of interdigital neuritis of the foot (Morton's neuroma). (16878772)
2005
27
Pinealectomy exaggerates and melatonin treatment suppresses neuroma formation of transected sciatic nerve in rats: gross morphological, histological and stereological analysis. (15813906)
2005
28
Elevated ankyrin G in a plexiform neurofibroma and neuromas associated with pain. (15519868)
2004
29
Management of unilateral acoustic neuroma in a 72-year-old patient with contralateral congenital deafness. (12447251)
2002
30
Composite dermatofibrosarcoma protuberans-giant cell fibroblastoma recurring as BednA!r tumor-giant cell fibroblastoma with mucoid lakes and with amputation neuroma. (12629865)
2002
31
Acoustic neuroma surgery and tinnitus. (12115076)
2002
32
Symptomatic subdural hygroma and temporal lobe edema after translabyrinthine removal of acoustic neuroma. (17167613)
2001
33
Acoustic neuroma: predominance of Antoni type B cells in tumors of patients with vestibular paresis. (11300272)
2001
34
Cerebrospinal fluid leak after acoustic neuroma surgery: influence of tumor size and surgical approach on incidence and response to treatment. (11213957)
2001
35
Nuances in acoustic neuroma surgery. (11504109)
2001
36
Vasoactive treatment for hearing preservation in acoustic neuroma surgery. (11702866)
2001
37
Impact of facial paralysis on patients with acoustic neuroma. (10983957)
2000
38
Acoustic neuroma: outcome of surgical resection and study on the anatomy of facial and cochlear nerves. (10575527)
1999
39
Management of acoustic neuroma. (10206835)
1999
40
Stereocilia-like structures in the endolymphatic sac in MAcniA"re's disease and acoustic neuroma. (9892873)
1999
41
Suboccipital resection of a medial acoustic neuroma with hearing preservation. (10321887)
1999
42
Disability from vestibular symptoms after acoustic neuroma resection. (9455958)
1998
43
Acoustic neuroma presenting as orofacial anethesia. (11507494)
1998
44
Intra-operative monitoring in acoustic neuroma surgery. (9785586)
1998
45
Pneumocephalus after acoustic neuroma surgery. (9831162)
1998
46
Facial nerve injury in acoustic neuroma (vestibular schwannoma) surgery: etiology and prevention. (9202266)
1997
47
Individualizing hearing preservation in acoustic neuroma surgery. (9261005)
1997
48
Sensorineural hearing loss and cerebellopontine angle lesions. Not always an acoustic neuroma--a pictorial essay. (9156313)
1997
49
Evidence for CGRP accumulation and activity in experimental neuromas. (7864183)
1995
50
Comparative light-microscopic and immunohistochemical study of traumatic and palisaded encapsulated neuromas of the skin. (1281969)
1992

Variations for Neuroma

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Expression for genes affiliated with Neuroma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Neuroma

Search GEO for disease gene expression data for Neuroma.

Pathways for genes affiliated with Neuroma

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Compounds for genes affiliated with Neuroma

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46Novoseek, 25HMDB, 12DrugBank
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Compounds related to Neuroma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1potassium46 25 1210.9VHL, AQP4, GDNF

GO Terms for genes affiliated with Neuroma

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17Gene Ontology
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Biological processes related to Neuroma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1response to X-rayGO:0101659.5XRCC2, LIG4
2positive regulation of neurogenesisGO:0507699.4LIG4, XRCC2
3negative regulation of neuron apoptotic processGO:0435249.2XRCC2, LIG4, GDNF
4response to gamma radiationGO:0103329.2XRCC2, LIG4
5DNA repairGO:0062819.0XRCC2, LIG4, MUTYH

Products for genes affiliated with Neuroma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Neuroma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet