MCID: NRM004
MIFTS: 51

Neuroma

Categories: Neuronal diseases, Cancer diseases

Aliases & Classifications for Neuroma

MalaCards integrated aliases for Neuroma:

Name: Neuroma 12 51 41 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2001
MeSH 41 D009463
NCIt 46 C3275
UMLS 69 C0027858

Summaries for Neuroma

Disease Ontology : 12 A nervous system benign neoplasm that is characterized as a nerve tissue tumor.

MalaCards based summary : Neuroma is related to acoustic neuroma and multiple mucosal neuroma. An important gene associated with Neuroma is ANK3 (Ankyrin 3), and among its related pathways/superpathways are Developmental Biology and Neuroscience. The drugs Bupivacaine and Mepivacaine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and breast, and related phenotypes are Increased proliferation and behavior/neurological

Wikipedia : 72 A neuroma /njuːˈroʊmə/ (plural: neuromata or neuromas) is a growth or tumor of nerve tissue. Neuromas... more...

Related Diseases for Neuroma

Diseases related to Neuroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 229)
# Related Disease Score Top Affiliating Genes
1 acoustic neuroma 34.3 BICRA NF2 TGFB1
2 multiple mucosal neuroma 33.7 ENO2 RET
3 neurofibromatosis, type iv, of riccardi 33.0 NF2 RET S100B
4 multiple endocrine neoplasia, type iib 32.5 CALCA GDNF RET
5 meningioma, familial 30.0 GFAP NF2 S100B SMARCB1
6 ependymoma 30.0 GFAP NF2 S100B
7 laryngitis 29.9 FGF2 TGFB1
8 multiple endocrine neoplasia 29.8 CALCA GDNF RET
9 medullomyoblastoma 29.7 ENO2 GFAP SMARCB1
10 malignant peripheral nerve sheath tumor 29.6 NF2 S100B SMARCB1
11 paine syndrome 29.4 NGF SCN10A TRPV1
12 neurilemmoma 29.2 ENO2 GFAP NF2 S100B SMARCB1
13 thyroid carcinoma, familial medullary 28.9 CALCA ENO2 GDNF RET
14 pheochromocytoma 28.7 CALCA ENO2 GDNF NGF RET
15 neuroma biliary tract 11.9
16 neurofibromatosis, type ii 11.0
17 neurofibromatosis, type i 11.0
18 klumpke paralysis 11.0
19 erb-duchenne and dejerine-klumpke palsies 10.9
20 lung meningioma 10.6 ENO2 NF2
21 cerebral convexity meningioma 10.6 GFAP NF2
22 meningothelial meningioma 10.6 ENO2 NF2
23 primitive neuroectodermal tumor of the cervix uteri 10.6 ENO2 GFAP
24 intraventricular meningioma 10.5 GFAP NF2
25 bednar tumor 10.5 ENO2 S100B
26 cerebellar medulloblastoma 10.5 ENO2 GFAP
27 middle cerebral artery infarction 10.5 ENO2 S100B
28 gemistocytic astrocytoma 10.5 GFAP S100B
29 fibrous meningioma 10.5 NF2 S100B
30 ossifying fibromyxoid tumor 10.5 ENO2 S100B
31 episodic pain syndrome, familial, 1 10.5
32 central nervous system primitive neuroectodermal neoplasm 10.5 ENO2 GFAP
33 chordoid meningioma 10.5 GFAP S100B
34 subependymal glioma 10.5 ENO2 GFAP
35 benign ependymoma 10.5 ENO2 GFAP NF2
36 plexiform schwannoma 10.5 ENO2 GFAP NF2
37 askin's tumor 10.5 ENO2 NGF
38 chordoid glioma 10.4 GFAP NF2 S100B
39 syringocystadenoma papilliferum 10.4 GFAP S100B
40 anaplastic ependymoma 10.4 GFAP NF2 S100B
41 intracranial cysts 10.4 ENO2 GFAP S100B
42 clear cell ependymoma 10.4 ENO2 GFAP NF2
43 pineocytoma 10.4 ENO2 GFAP S100B
44 papillary ependymoma 10.4 ENO2 GFAP S100B
45 subependymal giant cell astrocytoma 10.4 ENO2 GFAP S100B
46 granular cell tumor 10.4 ENO2 GFAP S100B
47 dysembryoplastic neuroepithelial tumor 10.4 GFAP S100B
48 traumatic brain injury 10.4 ENO2 GFAP S100B
49 optic nerve glioma 10.4 ENO2 GFAP S100B
50 spinal cancer 10.4 GFAP NF2

Graphical network of the top 20 diseases related to Neuroma:



Diseases related to Neuroma

Symptoms & Phenotypes for Neuroma

GenomeRNAi Phenotypes related to Neuroma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased proliferation GR00094-A 8.62 NF2 SMARCB1

MGI Mouse Phenotypes related to Neuroma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.32 TGFB1 S100B SCN10A TRPV1 SEMA3F SMARCB1
2 homeostasis/metabolism MP:0005376 10.15 TGFB1 S100B SCN10A TRPV1 SEMA3F SMARCB1
3 growth/size/body region MP:0005378 10.14 TGFB1 TRPV1 SEMA3F SMARCB1 RET GFAP
4 cellular MP:0005384 10.13 RET TGFB1 TRPV1 SEMA3F SMARCB1 GDNF
5 cardiovascular system MP:0005385 10.11 TGFB1 SCN10A TRPV1 SMARCB1 RET GFAP
6 nervous system MP:0003631 9.97 TGFB1 SCN10A TRPV1 SEMA3F SMARCB1 GFAP
7 muscle MP:0005369 9.87 RET TGFB1 SMARCB1 GDNF GFAP FGF2
8 neoplasm MP:0002006 9.8 TGFB1 TRPV1 SMARCB1 NF2 FGF2 FGFR4
9 respiratory system MP:0005388 9.5 TGFB1 SCN10A RET ANK3 ENO2 NF2
10 vision/eye MP:0005391 9.17 TGFB1 SEMA3F SMARCB1 GFAP NF2 FGF2

Drugs & Therapeutics for Neuroma

Drugs for Neuroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 143)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4 38396-39-3, 2180-92-9 2474
2
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4 Anesthetics Phase 4,Phase 1,Early Phase 1
5 Anesthetics, Local Phase 4,Phase 1,Early Phase 1
6 Central Nervous System Depressants Phase 4,Phase 2,Phase 1,Early Phase 1
7 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Early Phase 1
8 Anti-Inflammatory Agents Phase 4,Phase 2
9 glucocorticoids Phase 4
10 Hormone Antagonists Phase 4
11 Hormones Phase 4
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
13 Anti-Infective Agents Phase 4,Phase 2,Phase 1,Early Phase 1
14 Immunosuppressive Agents Phase 4,Phase 2,Phase 1,Early Phase 1
15 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Gentamicins Phase 4
17 triamcinolone acetonide Phase 4
18 Triamcinolone diacetate Phase 4
19 Triamcinolone hexacetonide Phase 4
20
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
21
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
22
Mechlorethamine Approved, Investigational Phase 3,Phase 2 51-75-2 4033
23
Cyclophosphamide Approved, Investigational Phase 2, Phase 3 50-18-0, 6055-19-2 2907
24
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
25 Protein Kinase Inhibitors Phase 2, Phase 3,Early Phase 1
26 Alkylating Agents Phase 3,Phase 2,Phase 1
27 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1,Early Phase 1
28 Isophosphamide mustard Phase 3,Phase 2 0
29 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
30 Imatinib Mesylate Phase 2, Phase 3 123596
31
Capsaicin Approved Phase 2,Phase 1 404-86-4 1548943
32
Bevacizumab Approved, Investigational Phase 2,Phase 1 216974-75-3
33
Mexiletine Approved, Investigational Phase 2 31828-71-4 4178
34
Morphine Approved, Investigational Phase 2 57-27-2 5288826
35
Everolimus Approved Phase 2,Phase 1,Early Phase 1 159351-69-6 6442177
36
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
37
Sirolimus Approved, Investigational Phase 2,Phase 1,Early Phase 1 53123-88-9 46835353 6436030 5284616
38
Dacarbazine Approved, Investigational Phase 2,Phase 1 4342-03-4 5351166
39
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
40
Etoposide Approved Phase 2 33419-42-0 36462
41
Lenograstim Approved, Investigational Phase 2 135968-09-1
42
Acetylcholine Approved Phase 2 51-84-3 187
43
Axitinib Approved, Investigational Phase 2 319460-85-0 6450551
44
nivolumab Approved Phase 2 946414-94-4
45
Pembrolizumab Approved Phase 2 1374853-91-4
46
Tacrolimus Approved, Investigational Phase 1, Phase 2 104987-11-3 445643 439492
47
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
48
Adenosine Approved, Investigational Phase 2 58-61-7 60961
49
Trastuzumab Approved, Investigational Phase 2 180288-69-1 9903
50
Xylometazoline Approved, Investigational Phase 1, Phase 2 526-36-3 5709

Interventional clinical trials:

(show top 50) (show all 128)

# Name Status NCT ID Phase Drugs
1 Pathophysiology of Post Amputation Pain Completed NCT01632709 Phase 4 Bupivacaine;Placebo
2 A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options Completed NCT00948025 Phase 4
3 Blind and Ultrasound Guided Injection in Morton Neuroma Recruiting NCT03046108 Phase 4 blind injection of Mepivacaine;blind injection of Triamcinolone;guided injection of mepivacaine;guided injection of Triamcinolone
4 Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function Recruiting NCT02415257 Phase 4 Gentamicin
5 Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function Recruiting NCT02379754 Phase 4 Gentamicins
6 Stereotactic Radiation in Vestibular Schwannoma Unknown status NCT01449604 Phase 3
7 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
8 Cyberknife Radiosurgery for Patients With Neurinomas Recruiting NCT02055859 Phase 3
9 Vestibular Schwannoma - Radiosurgery or Expectation: V-REX. Recruiting NCT02249572 Phase 2, Phase 3
10 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
11 Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors Terminated NCT00427583 Phase 2, Phase 3 imatinib mesylate
12 A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02283957 Phase 2 CNTX-4975
13 ALGRX 4975 in the Treatment of Patients With Morton's Neuroma Completed NCT00130962 Phase 2 ALGRX 4975
14 An Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02678793 Phase 2 CNTX-4975
15 Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2) Completed NCT01207687 Phase 2
16 Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT00973739 Phase 2 Lapatinib
17 Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2 Completed NCT00004437 Phase 2
18 Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain Completed NCT00383682 Phase 2 morphine and mexiletine
19 Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT02104323 Phase 2 Endostatin
20 Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients Completed NCT01490476 Phase 2 RAD001
21 Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2 Completed NCT01419639 Phase 2 Everolimus (RAD001) , Afinitor®
22 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01653028 Phase 2 Alisertib
23 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
24 Sorafenib and Dacarbazine in Soft Tissue Sarcoma Completed NCT00837148 Phase 2 Sorafenib and Dacarbazine
25 Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors Completed NCT00304083 Phase 2 doxorubicin hydrochloride;etoposide;ifosfamide
26 S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor Completed NCT00068367 Phase 2 erlotinib hydrochloride
27 RGD PET/MRI in Sporadic Vestibular Schwannoma Recruiting NCT03393689 Phase 2 One injection of 68Ga-NODAGA-E[c(RGDyK)]2
28 Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular Schwannoma Recruiting NCT01199978 Phase 2
29 Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors Recruiting NCT02986919 Phase 2 CPI-0610
30 Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas Recruiting NCT03231306 Phase 2 Binimetinib
31 Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Recruiting NCT02934256 Phase 2 Icotinib
32 Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas Recruiting NCT02129647 Phase 2 Axitinib
33 Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors Recruiting NCT03095248 Phase 2 Selumetinib
34 Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusion Cancers Recruiting NCT03215511 Phase 1, Phase 2 LOXO-195
35 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
36 A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery Recruiting NCT02691026 Phase 2 Pembrolizumab
37 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Recruiting NCT02601209 Phase 1, Phase 2 Pazopanib Hydrochloride;Sapanisertib
38 PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors Recruiting NCT02584647 Phase 1, Phase 2 PLX3397;Sirolimus
39 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2 Dexrazoxane;Doxorubicin;Olaratumab
40 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
41 Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma Active, not recruiting NCT01345136 Phase 2 RAD001, everolimus
42 Axillary Reverse Mapping Active, not recruiting NCT00572481 Phase 2
43 Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas Active, not recruiting NCT01767792 Phase 2 Bevacizumab
44 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Active, not recruiting NCT01125046 Phase 2
45 AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas Active, not recruiting NCT02831257 Phase 2 AZD2014
46 Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma Active, not recruiting NCT02452554 Phase 2
47 SARC023: Ganetespib and Sirolimos in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) Active, not recruiting NCT02008877 Phase 1, Phase 2 ganetespib;Sirolimus
48 SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors Active, not recruiting NCT01661283 Phase 2 everolimus;bevacizumab
49 Trial of Dasatinib in Advanced Sarcomas Active, not recruiting NCT00464620 Phase 2 Dasatinib
50 Study of Aspirin in Patients With Vestibular Schwannoma Not yet recruiting NCT03079999 Phase 2 Aspirin;Placebo

Search NIH Clinical Center for Neuroma

Cochrane evidence based reviews: neuroma

Genetic Tests for Neuroma

Anatomical Context for Neuroma

MalaCards organs/tissues related to Neuroma:

38
Brain, Bone, Breast, Skin, Testes, Liver, Tongue

Publications for Neuroma

Articles related to Neuroma:

(show top 50) (show all 1035)
# Title Authors Year
1
Risk factors and the associated cutoff values for failure of corticosteroid injection in treatment of Morton's neuroma. ( 29230531 )
2018
2
Increased sensibility to acute acoustic and blast trauma among patients with acoustic neuroma. ( 29184217 )
2018
3
Transcanal Transpromontorial Acoustic Neuroma Surgery: Results and Facial Nerve Outcomes. ( 29227438 )
2018
4
The impact of acoustic neuroma on long-term quality-of-life outcomes in the United Kingdom. ( 29330600 )
2018
5
Endobronchial Mucosal Neuroma with Sarcoidosis. ( 29394980 )
2018
6
Novel experimental surgical strategy to prevent traumatic neuroma formation by combining a 3D-printed Y-tube with an autograft. ( 29424651 )
2018
7
Ophthalmic Complications Following Acoustic Neuroma Resection. ( 29253289 )
2018
8
Patient Decision Making in Vestibular Schwannoma: A Survey of the Acoustic Neuroma Association. ( 29436268 )
2018
9
Nonspecific Chronic Anteromedial Knee Pain Neuroma as a Cause of Infrapatellar Pain Syndrome: Case Study and Literature Review. ( 29404377 )
2018
10
Conservative treatment of vestibular schwannoma: growth and Penn Acoustic Neuroma Quality of Life scale in French language. ( 28872162 )
2017
11
Morton Neuroma ( 29262171 )
2017
12
Evaluation of Auditory Pathways Using DTI in Patients Treated with Gamma Knife Radiosurgery for Acoustic Neuroma: AA Preliminary Report. ( 28258282 )
2017
13
Treatment of Morton's neuroma: A systematic review. ( 29409240 )
2017
14
Impact of insurance status and race on receipt of treatment for acoustic neuroma: A national cancer database analysis. ( 28343920 )
2017
15
Corticosteroid Injection for the Treatment of Morton's Neuroma: A Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial. ( 28617064 )
2017
16
A late unusual complication after an open cholecystectomy: Amputation neuroma of the CBD causing obstructive jaundice. ( 28837915 )
2017
17
Symptomatic Neuroma Following Initial Amputation for Traumatic Digital Amputation. ( 28951100 )
2017
18
Post-transplant Amputation Traumatic Neuroma of the Hilum and Extrahepatic Duct in a Liver Donor. ( 28774160 )
2017
19
Peripheral nerve function estimation by linear model of multi-CMAP responses for surgical intervention in acoustic neuroma surgery. ( 29192065 )
2017
20
Intravenous Glomus Tumor Masquerading as Lateral Antebrachial Cutaneous Neuroma. ( 28344537 )
2017
21
Superficial papular neuroma: Case series of a new entity. ( 28627021 )
2017
22
Epineural Sheath Jacket as a New Surgical Technique for Neuroma Prevention in the Rat Sciatic Nerve Model. ( 28570461 )
2017
23
Postablation neuroma of the myometrium - a report of 5 cases. ( 28843713 )
2017
24
The Top 50 Most-Cited Articles on Acoustic Neuroma. ( 29288105 )
2017
25
Pacinian Corpuscles Neuroma. An Exceptional Cause of Pain in the Hand. ( 28506166 )
2017
26
A systematic review about the position-related complications of acoustic neuroma surgery via suboccipital retrosigmoid approach: Sitting versus lateral. ( 28761510 )
2017
27
Complications of the Middle Cranial Fossa Approach for Acoustic Neuroma Removal. ( 28816690 )
2017
28
Peripheral Neuromodulation for the Treatment of Postamputation Neuroma Pain: A Case Report. ( 27828784 )
2017
29
Evaluation of surgical treatment for neuropathic pain from neuroma in patients with injured peripheral nerves. ( 28621630 )
2017
30
Morton's Neuroma (Interdigital Neuralgia) Treated with Metatarsal Sliding Osteotomy. ( 29200487 )
2017
31
Influencing Factors Analysis of Facial Nerve Function after the Microsurgical Resection of Acoustic Neuroma. ( 28264236 )
2017
32
Probabilistic Multiple-Bias Modeling Applied to the Canadian Data From the Interphone Study of Mobile Phone Use and Risk of Glioma, Meningioma, Acoustic Neuroma, and Parotid Gland Tumors. ( 28535174 )
2017
33
Operative Mortality Rates of Acoustic Neuroma Surgery: A National Cancer Database Analysis. ( 28187056 )
2017
34
Validation of the Penn Acoustic Neuroma Quality-of-Life Scale (PANQOL) for Spanish-Speaking Patients. ( 28116984 )
2017
35
Arytenoid neuromas are a recognized feature of SOS1 mutations causing pure mucosal neuroma syndrome. ( 28863001 )
2017
36
Validation of the facial dysfunction domain of the Penn Acoustic Neuroma Quality-of-Life (PANQOL) Scale. ( 28391530 )
2017
37
Amputation neuroma mimicking lymph node metastasis of remnant gastric cancer: a case report. ( 29234894 )
2017
38
Signs and Symptoms of Acoustic Neuroma at Initial Presentation: An Exploratory Analysis. ( 29348989 )
2017
39
Homogeneous white patch in dermoscopy of solitary circumscribed neuroma. ( 28087044 )
2017
40
Palisaded Encapsulated (Solitary Circumscribed) Neuroma of the Buccal Mucosa: a Rare Case. ( 29201976 )
2017
41
Pro and anti-inflammatory cytokine levels (TNF-I+, IL-1I^, IL-6 and IL-10) in rat model of neuroma. ( 28462800 )
2017
42
Acoustic Neuroma (Vestibular Schwannoma) ( 29262098 )
2017
43
Postoperative Headache after Undergoing Acoustic Neuroma Surgery via the Retrosigmoid Approach. ( 29021412 )
2017
44
Ultrasound Evaluation of Morton Neuroma Before and After Laser Therapy. ( 27897032 )
2017
45
Reexcision Perineural Invasion and Epithelial Sheath Neuroma Possibly on a Spectrum of Postinjury Reactive Hyperplasia Mediated by IL-6. ( 27749287 )
2017
46
Eccrine spiradenoma mimicking a painful traumatic neuroma: case report. ( 29076781 )
2017
47
Three Cycles of Radiofrequency Ablation Are More Efficacious Than Two in the Management of Morton's Neuroma. ( 28513218 )
2017
48
The clinical diagnosis of symptomatic forefoot neuroma in the general population: a Delphi consensus study. ( 29299065 )
2017
49
Regarding: Traumatic Neuroma After Hysterectomy. A Rare Cause of Posthysterectomy Pelvic Pain. ( 27818265 )
2017
50
Swimming Training Reduces Neuroma Pain by Regulating Neurotrophins. ( 28846565 )
2017

Variations for Neuroma

Expression for Neuroma

Search GEO for disease gene expression data for Neuroma.

Pathways for Neuroma

Pathways related to Neuroma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 ANK3 FGF2 FGFR4 GDNF RET SCN10A
2 12.09 CALCA ENO2 GFAP NF2 NGF RET
3 11.66 GDNF GFAP TGFB1
4 11.44 FGF2 FGFR4 TGFB1
5 11.13 CALCA FGF2 TGFB1
6 11 FGF2 FGFR4 GDNF GFAP NGF S100B
7 10.56 FGF2 FGFR4 GFAP NGF TGFB1

GO Terms for Neuroma

Cellular components related to Neuroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.46 ANK3 CALCA NF2 TRPV1
2 axon GO:0030424 9.26 ANK3 CALCA RET TGFB1
3 neuronal cell body GO:0043025 9.1 CALCA ENO2 RET S100B TGFB1 TRPV1

Biological processes related to Neuroma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.77 FGF2 FGFR4 GDNF S100B TGFB1
2 regulation of receptor activity GO:0010469 9.72 CALCA FGF2 GDNF NGF TGFB1
3 positive regulation of gene expression GO:0010628 9.65 ANK3 FGFR4 NGF RET TGFB1
4 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.52 GDNF TGFB1
5 negative regulation of DNA replication GO:0008156 9.51 NF2 TGFB1
6 hyaluronan catabolic process GO:0030214 9.49 FGF2 TGFB1
7 detection of temperature stimulus involved in sensory perception of pain GO:0050965 9.48 CALCA TRPV1
8 negative regulation of cell-cell adhesion GO:0022408 9.46 NF2 TGFB1
9 lens fiber cell differentiation GO:0070306 9.43 NF2 TGFB1
10 enteric nervous system development GO:0048484 9.4 GDNF RET
11 MAPK cascade GO:0000165 9.35 FGF2 FGFR4 GDNF RET TGFB1
12 ureteric bud development GO:0001657 9.33 GDNF RET TGFB1
13 response to pain GO:0048265 8.8 CALCA RET TRPV1

Molecular functions related to Neuroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 FGF2 GDNF NGF TGFB1
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.92 FGF2 FGFR4 GDNF RET

Sources for Neuroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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