MCID: NRM004
MIFTS: 46

Neuroma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Neuroma

MalaCards integrated aliases for Neuroma:

Name: Neuroma 12 52 42 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2001
MeSH 42 D009463
NCIt 47 C3275
UMLS 69 C0027858

Summaries for Neuroma

Disease Ontology : 12 A nervous system benign neoplasm that is characterized as a nerve tissue tumor.

MalaCards based summary : Neuroma is related to multiple endocrine neoplasia iib and myoma. An important gene associated with Neuroma is ANK3 (Ankyrin 3), and among its related pathways/superpathways are Developmental Biology and Neuroscience. The drugs Bupivacaine and Mepivacaine have been mentioned in the context of this disorder. Affiliated tissues include brain, bone and breast, and related phenotypes are behavior/neurological and growth/size/body region

Wikipedia : 72 A neuroma /njuːˈroʊmə/ (plural: neuromata or neuromas) is a growth or tumor of nerve tissue. Neuromas... more...

Related Diseases for Neuroma

Diseases related to Neuroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 203)
id Related Disease Score Top Affiliating Genes
1 multiple endocrine neoplasia iib 32.3 CALCA GDNF RET
2 myoma 30.3 ENO2 S100B
3 cavernous hemangioma 29.5 ENO2 GFAP RET
4 pheochromocytoma 28.5 CALCA ENO2 GDNF NGF RET
5 acoustic neuroma 12.4
6 multiple mucosal neuroma 12.0
7 neuroma biliary tract 11.8
8 neurofibromatosis, type 1 11.5
9 neurofibromatosis, type 2 11.2
10 klumpke paralysis 10.9
11 verruciform xanthoma of skin 10.8 ENO2 NF2
12 renal pelvis urothelial papilloma 10.8 GFAP NF2
13 gallbladder papillary carcinoma 10.8 ENO2 NF2
14 anovulation 10.8 GFAP NF2
15 intellectual disability-polydactyly-uncombable hair syndrome 10.8 ENO2 GFAP
16 nodular medulloblastoma 10.8 ENO2 GFAP
17 benallegue lacete syndrome 10.8 ENO2 S100B
18 basosquamous carcinoma 10.8 GFAP NF2
19 erb-duchenne and dejerine-klumpke palsies 10.8
20 spleen angiosarcoma 10.7 GFAP S100B
21 ovarian mucinous cystadenofibroma 10.7 GFAP S100B
22 noninvasive malignant thymoma 10.7 NF2 S100B
23 mucinous ovarian cystadenoma 10.7 GFAP S100B
24 enteric pattern testicular yolk sac tumor 10.7 ENO2 S100B
25 vulvar benign neoplasm 10.7 ENO2 GFAP
26 motor neuron disease 10.7 ENO2 S100B
27 brain glioma 10.7 ENO2 GFAP
28 reticular pattern testicular yolk sac tumor 10.7 GFAP S100B
29 cauda equina neoplasm 10.7 ENO2 GFAP NF2
30 cauda equina intradural extramedullary astrocytoma 10.7 ENO2 GFAP
31 demyelinating disease 10.7 ENO2 GFAP NF2
32 behcet's syndrome arthropathy 10.6 ENO2 GFAP PCNA
33 toxic pneumonitis 10.6 ENO2 GFAP NF2
34 pleural empyema 10.6 GFAP NF2 S100B
35 anaplastic oligodendroglioma 10.6 GFAP NF2 S100B
36 pharynx carcinoma in situ 10.6 ENO2 NGF
37 third cranial nerve disease 10.6 GFAP NF2
38 meningitis and encephalitis 10.6 ENO2 GFAP S100B
39 epidermolysa bullosa simplex with muscular dystrophy 10.6 GFAP NF2 S100B
40 pituitary dwarfism with large sella turcica 10.6 ENO2 GFAP S100B
41 adenofibroma 10.6 GFAP S100B
42 pediatric ependymoma 10.6 ENO2 GFAP S100B
43 mixed epithelial stromal tumour 10.6 ENO2 GFAP S100B
44 skin glomus tumor 10.6 ENO2 GFAP S100B
45 ulcerative colitis 10.6 ENO2 GFAP S100B
46 cervical adenomyoma 10.6 ENO2 GFAP S100B
47 brain meningioma 10.6 ENO2 GFAP S100B
48 sternum cancer 10.6 ENO2 GFAP S100B
49 spinal cord glioma 10.6 ENO2 GFAP PCNA
50 inflammatory leiomyosarcoma 10.6 ENO2 GFAP S100B

Graphical network of the top 20 diseases related to Neuroma:



Diseases related to Neuroma

Symptoms & Phenotypes for Neuroma

MGI Mouse Phenotypes related to Neuroma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 10.18 ENO2 FGF2 GDNF GFAP NF2 NGF
2 growth/size/body region MP:0005378 10.06 NGF PCNA RET SEMA3F TGFB1 TRPV1
3 homeostasis/metabolism MP:0005376 10 FGF2 FGFR4 GFAP NF2 NGF RET
4 nervous system MP:0003631 9.73 ANK3 ENO2 FGF2 GDNF GFAP NF2
5 neoplasm MP:0002006 9.63 FGF2 FGFR4 NF2 RET TGFB1 TRPV1
6 respiratory system MP:0005388 9.17 ANK3 ENO2 FGFR4 NF2 RET SCN10A

Drugs & Therapeutics for Neuroma

Drugs for Neuroma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 143)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4 2180-92-9, 38396-39-3 2474
2
Mepivacaine Approved, Vet_approved Phase 4 96-88-8 4062
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4 Anesthetics Phase 4,Phase 1,Early Phase 1
5 Anesthetics, Local Phase 4,Phase 1,Early Phase 1
6 Central Nervous System Depressants Phase 4,Phase 2,Phase 1,Early Phase 1
7 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 1,Early Phase 1
8 Anti-Inflammatory Agents Phase 4,Phase 2
9 Anti-Infective Agents Phase 4,Phase 2,Phase 1,Early Phase 1
10 Immunosuppressive Agents Phase 4,Phase 2,Phase 1,Early Phase 1
11 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
12 Gentamicins Phase 4
13 glucocorticoids Phase 4
14 Hormone Antagonists Phase 4
15 Hormones Phase 4
16 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
17 triamcinolone acetonide Phase 4
18 Triamcinolone diacetate Phase 4
19 Triamcinolone hexacetonide Phase 4
20
Doxorubicin Approved, Investigational Phase 3,Phase 2,Phase 1 23214-92-8 31703
21
Ifosfamide Approved Phase 3,Phase 2 3778-73-2 3690
22
Mechlorethamine Approved Phase 3,Phase 2 51-75-2 4033
23
Cyclophosphamide Approved, Investigational Phase 2, Phase 3 50-18-0, 6055-19-2 2907
24
Doxil Approved June 1999 Phase 3,Phase 2,Phase 1 31703
25 Protein Kinase Inhibitors Phase 2, Phase 3,Early Phase 1
26 Alkylating Agents Phase 3,Phase 2,Phase 1
27 Antibiotics, Antitubercular Phase 3,Phase 2,Phase 1,Early Phase 1
28 Isophosphamide mustard Phase 3,Phase 2
29 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
30 Imatinib Mesylate Phase 2, Phase 3 123596
31
Capsaicin Approved Phase 2,Phase 1 404-86-4 1548943
32
Bevacizumab Approved, Investigational Phase 2,Phase 1 216974-75-3
33
Mexiletine Approved Phase 2 31828-71-4 4178
34
Morphine Approved, Investigational Phase 2 57-27-2 5288826
35
Everolimus Approved Phase 2,Phase 1,Early Phase 1 159351-69-6 6442177
36
Miconazole Approved, Investigational, Vet_approved Phase 2,Phase 1,Early Phase 1 22916-47-8 4189
37
Sirolimus Approved, Investigational Phase 2,Phase 1,Early Phase 1 53123-88-9 5284616 6436030 46835353
38
Dacarbazine Approved, Investigational Phase 2,Phase 1 4342-03-4 5351166
39
Sorafenib Approved, Investigational Phase 2 284461-73-0 216239 406563
40
Etoposide Approved Phase 2 33419-42-0 36462
41
Lenograstim Approved Phase 2 135968-09-1
42
Acetylcholine Approved Phase 2 51-84-3 187
43
Axitinib Approved, Investigational Phase 2 319460-85-0 6450551
44
nivolumab Approved Phase 2 946414-94-4
45
Pembrolizumab Approved Phase 2 1374853-91-4
46
Tacrolimus Approved, Investigational Phase 1, Phase 2 104987-11-3 445643 439492
47
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
48
Adenosine Approved, Investigational Phase 2 58-61-7 60961
49
Trastuzumab Approved, Investigational Phase 2 180288-69-1 9903
50
Xylometazoline Approved Phase 1, Phase 2 526-36-3 5709

Interventional clinical trials:

(show top 50) (show all 124)

id Name Status NCT ID Phase Drugs
1 Pathophysiology of Post Amputation Pain Completed NCT01632709 Phase 4 Bupivacaine;Placebo
2 A Comparative Post-marketing Study of Commercially Available Peripheral Nerve Gap Repair Options Completed NCT00948025 Phase 4
3 Blind and Ultrasound Guided Injection in Morton Neuroma Recruiting NCT03046108 Phase 4 blind injection of Mepivacaine;blind injection of Triamcinolone;guided injection of mepivacaine;guided injection of Triamcinolone
4 Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function Recruiting NCT02415257 Phase 4 Gentamicin
5 Gentamicin Treatment Prior to Schwannoma Surgery - Residual Function Recruiting NCT02379754 Phase 4 Gentamicins
6 Stereotactic Radiation in Vestibular Schwannoma Unknown status NCT01449604 Phase 3
7 Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma Completed NCT00346164 Phase 3 doxorubicin hydrochloride;ifosfamide
8 Cyberknife Radiosurgery for Patients With Neurinomas Recruiting NCT02055859 Phase 3
9 Vestibular Schwannoma - Radiosurgery or Expectation: V-REX. Recruiting NCT02249572 Phase 2, Phase 3
10 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
11 Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath Tumors Terminated NCT00427583 Phase 2, Phase 3 imatinib mesylate
12 ALGRX 4975 in the Treatment of Patients With Morton's Neuroma Completed NCT00130962 Phase 2 ALGRX 4975
13 A Study to Evaluate the Efficacy and Safety of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02283957 Phase 2 CNTX-4975
14 An Study to Evaluate the Safety and Efficacy of CNTX-4975 in Subjects With Painful Intermetatarsal Neuroma (Morton's Neuroma) Completed NCT02678793 Phase 2 CNTX-4975
15 Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2) Completed NCT01207687 Phase 2
16 Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT00973739 Phase 2 Lapatinib
17 Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2 Completed NCT00004437 Phase 2
18 Efficacy of Opioids and Mexiletine for the Treatment of Postamputation Pain Completed NCT00383682 Phase 2 morphine and mexiletine
19 Endostatin Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Completed NCT02104323 Phase 2 Endostatin
20 Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients Completed NCT01490476 Phase 2 RAD001
21 Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2 Completed NCT01419639 Phase 2 Everolimus (RAD001) , Afinitor®
22 Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma Completed NCT01154452 Phase 1, Phase 2 Gamma-Secretase Inhibitor RO4929097;Vismodegib
23 Sorafenib and Dacarbazine in Soft Tissue Sarcoma Completed NCT00837148 Phase 2 Sorafenib and Dacarbazine
24 Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors Completed NCT00304083 Phase 2 doxorubicin hydrochloride;etoposide;ifosfamide
25 S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor Completed NCT00068367 Phase 2 erlotinib hydrochloride
26 Hearing Outcomes Using Fractionated Proton Radiation Therapy for Vestibular Schwannoma Recruiting NCT01199978 Phase 2
27 Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma Recruiting NCT01345136 Phase 2 RAD001, everolimus
28 Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors Recruiting NCT02934256 Phase 2 Icotinib
29 Study of Axitinib in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas Recruiting NCT02129647 Phase 2 Axitinib
30 Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors Recruiting NCT03095248 Phase 2 Selumetinib
31 Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusions or Non-fusion NTRK Cancers Recruiting NCT03215511 Phase 1, Phase 2 LOXO-195
32 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
33 A Study of Pembrolizumab in Patients With Malignant Peripheral Nerve Sheath Tumor (MPNST), Not Eligible for Curative Surgery Recruiting NCT02691026 Phase 2 Pembrolizumab
34 PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors Recruiting NCT02584647 Phase 1, Phase 2 PLX3397;Sirolimus
35 Doxorubicin With Upfront Dexrazoxane Plus Olaratumab for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma Recruiting NCT02584309 Phase 2 Dexrazoxane;Doxorubicin;Olaratumab
36 Gemcitabine Hydrochloride With or Without Pazopanib Hydrochloride in Treating Patients With Refractory Soft Tissue Sarcoma Recruiting NCT01532687 Phase 2 Gemcitabine Hydrochloride;Pazopanib Hydrochloride
37 Axillary Reverse Mapping Active, not recruiting NCT00572481 Phase 2
38 Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas Active, not recruiting NCT01767792 Phase 2 Bevacizumab
39 Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas Active, not recruiting NCT01125046 Phase 2
40 AZD2014 In NF2 Patients With Progressive or Symptomatic Meningiomas Active, not recruiting NCT02831257 Phase 2 AZD2014
41 Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma Active, not recruiting NCT02452554 Phase 2
42 SARC023: Ganetespib and Sirolimos in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors) Active, not recruiting NCT02008877 Phase 1, Phase 2 ganetespib;Sirolimus
43 SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors Active, not recruiting NCT01661283 Phase 2 everolimus;bevacizumab
44 Alisertib in Treating Patients With Advanced or Metastatic Sarcoma Active, not recruiting NCT01653028 Phase 2 Alisertib
45 Trial of Dasatinib in Advanced Sarcomas Active, not recruiting NCT00464620 Phase 2 Dasatinib
46 Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors Not yet recruiting NCT02986919 Phase 2 CPI-0610
47 Study of Aspirin in Patients With Vestibular Schwannoma Not yet recruiting NCT03079999 Phase 2 Aspirin;Placebo
48 Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas Not yet recruiting NCT03231306 Phase 2 Binimetinib
49 PTC299 for Treatment of Neurofibromatosis Type 2 Suspended NCT00911248 Phase 2 PTC299
50 Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma Suspended NCT02601209 Phase 1, Phase 2 Pazopanib Hydrochloride;Sapanisertib

Search NIH Clinical Center for Neuroma

Cochrane evidence based reviews: neuroma

Genetic Tests for Neuroma

Anatomical Context for Neuroma

MalaCards organs/tissues related to Neuroma:

39
Brain, Bone, Breast, Skin, Testes, Liver, Tongue

Publications for Neuroma

Articles related to Neuroma:

(show top 50) (show all 1013)
id Title Authors Year
1
Resection planning for robotic acoustic neuroma surgery. ( 28612038 )
2017
2
Complications of the Middle Cranial Fossa Approach for Acoustic Neuroma Removal. ( 28816690 )
2017
3
Epineural Sheath Jacket as a New Surgical Technique for Neuroma Prevention in the Rat Sciatic Nerve Model. ( 28570461 )
2017
4
Arytenoid neuromas are a recognized feature of SOS1 mutations causing pure mucosal neuroma syndrome. ( 28863001 )
2017
5
Impact of insurance status and race on receipt of treatment for acoustic neuroma: A national cancer database analysis. ( 28343920 )
2017
6
Swimming Training Reduces Neuroma Pain by Regulating Neurotrophins. ( 28846565 )
2017
7
Reexcision Perineural Invasion and Epithelial Sheath Neuroma Possibly on a Spectrum of Postinjury Reactive Hyperplasia Mediated by IL-6. ( 27749287 )
2017
8
Influence of Blood Flow on the Neuroma Formation after Transposition of the Nerve Stump into Vein: Experimental and Clinical Study. ( 28442857 )
2017
9
Regarding: Traumatic Neuroma After Hysterectomy. A Rare Cause of Posthysterectomy Pelvic Pain. ( 27818265 )
2017
10
Symptomatic Neuroma Following Initial Amputation for Traumatic Digital Amputation. ( 28951100 )
2017
11
Conservative treatment of vestibular schwannoma: growth and Penn Acoustic Neuroma Quality of Life scale in French language. ( 28872162 )
2017
12
Pro and anti-inflammatory cytokine levels (TNF-I+, IL-1I^, IL-6 and IL-10) in rat model of neuroma. ( 28462800 )
2017
13
Evaluation of surgical treatment for neuropathic pain from neuroma in patients with injured peripheral nerves. ( 28621630 )
2017
14
Postablation neuroma of the myometrium - a report of 5 cases. ( 28843713 )
2017
15
A late unusual complication after an open cholecystectomy: Amputation neuroma of the CBD causing obstructive jaundice. ( 28837915 )
2017
16
Three Cycles of Radiofrequency Ablation Are More Efficacious Than Two in the Management of Morton's Neuroma. ( 28513218 )
2017
17
Validation of the facial dysfunction domain of the Penn Acoustic Neuroma Quality-of-Life (PANQOL) Scale. ( 28391530 )
2017
18
Pacinian Corpuscles Neuroma. An Exceptional Cause of Pain in the Hand. ( 28506166 )
2017
19
Superficial papular neuroma: Case series of a new entity. ( 28627021 )
2017
20
Multistep translation and cultural adaptation of the Penn acoustic neuroma quality-of-life scale for German-speaking patients. ( 28861705 )
2017
21
Intravenous Glomus Tumor Masquerading as Lateral Antebrachial Cutaneous Neuroma. ( 28344537 )
2017
22
Influencing Factors Analysis of Facial Nerve Function after the Microsurgical Resection of Acoustic Neuroma. ( 28264236 )
2017
23
Ultrasound Evaluation of Morton Neuroma Before and After Laser Therapy. ( 27897032 )
2017
24
Operative Mortality Rates of Acoustic Neuroma Surgery: A National Cancer Database Analysis. ( 28187056 )
2017
25
Post-transplant Amputation Traumatic Neuroma of the Hilum and Extrahepatic Duct in a Liver Donor. ( 28774160 )
2017
26
Probabilistic Multiple-Bias Modeling Applied to the Canadian Data From the Interphone Study of Mobile Phone Use and Risk of Glioma, Meningioma, Acoustic Neuroma, and Parotid Gland Tumors. ( 28535174 )
2017
27
Evaluation of Auditory Pathways Using DTI in Patients Treated with Gamma Knife Radiosurgery for Acoustic Neuroma: AA Preliminary Report. ( 28258282 )
2017
28
Homogeneous white patch in dermoscopy of solitary circumscribed neuroma. ( 28087044 )
2017
29
Peripheral Neuromodulation for the Treatment of Postamputation Neuroma Pain: A Case Report. ( 27828784 )
2017
30
A systematic review about the position-related complications of acoustic neuroma surgery via suboccipital retrosigmoid approach: Sitting versus lateral. ( 28761510 )
2017
31
Validation of the Penn Acoustic Neuroma Quality-of-Life Scale (PANQOL) for Spanish-Speaking Patients. ( 28116984 )
2017
32
Corticosteroid Injection for the Treatment of Morton's Neuroma: A Prospective, Double-Blinded, Randomized, Placebo-Controlled Trial. ( 28617064 )
2017
33
Bowler's thumb: ultrasound diagnosis of a neuroma of the ulnar digital nerve of the thumb. ( 27600139 )
2016
34
SU-F-T-612: Investigation of Acoustic Neuroma Planning for Stereotactic Radiosurgery Utilizing Linac-Based Cone Collimators. ( 28046447 )
2016
35
Evolution of Patients With Immediate Complete Facial Paralysis Secondary to Acoustic Neuroma Surgery. ( 26719351 )
2016
36
Traumatic Neuroma After Hysterectomy and Bilateral Salpingo-Oophorectomy: A Rare Cause of Post Hysterectomy Pelvic Pain. ( 27423258 )
2016
37
Suspected Acoustic Neuroma Demyelinating Lesions. ( 27579562 )
2016
38
A randomized, double-blind, placebo-controlled trial of injected capsaicin for pain in Morton's neuroma. ( 26963851 )
2016
39
Painful pediatric traumatic neuroma: surgical management and clinical outcomes. ( 27179535 )
2016
40
Extracorporeal Shockwave Therapy in Patients with Morton's Neuroma A Randomized, Placebo-Controlled Trial. ( 27031544 )
2016
41
The Persistence of Tinnitus after Acoustic Neuroma Surgery. ( 27095048 )
2016
42
Traumatic neuroma on the digital tip: Immunohistochemical analysis of inflammatory signaling pathways. ( 26876467 )
2016
43
What factors predict the need for further intervention following corticosteroid injection of Morton's neuroma? ( 26869493 )
2016
44
Neuroma of the distal posterior interosseous nerve as a cause of persistent dorsal wrist pain. ( 27939442 )
2016
45
Corrigendum to "Histopathological Characterization of Tail Injury and Traumatic Neuroma Development after Tail Docking in Piglets" [J Comp Pathol 155 (1) (2016) 40-49]. ( 27567272 )
2016
46
The relationship between foot posture index, ankle equinus, body mass index and intermetatarsal neuroma. ( 27980684 )
2016
47
Treatment of a Recurrent Neuroma Within Nerve Allograft With Autologous Nerve Reconstruction. ( 27390572 )
2016
48
Traumatic Neuroma at the Inferior Mesenteric Artery Stump after Rectal Cancer Surgery: A Case Report and Literature Review. ( 27871166 )
2016
49
Reply: Hirano-Ali et al. (2016) reports a case of epithelial sheath neuroma. ( 27585072 )
2016
50
Percutaneous MR-Guided Cryoablation of Morton's Neuroma: Rationale and Technical Details After the First 20 Patients. ( 27189181 )
2016

Variations for Neuroma

Expression for Neuroma

Search GEO for disease gene expression data for Neuroma.

Pathways for Neuroma

Pathways related to Neuroma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.12 ANK3 FGF2 FGFR4 GDNF RET SCN10A
2 12.07 CALCA ENO2 GFAP NF2 NGF RET
3 11.66 GDNF GFAP TGFB1
4 11.37 FGF2 FGFR4 TGFB1
5 11.31 FGF2 FGFR4 NGF TGFB1
6 11.13 CALCA FGF2 TGFB1
7 11 FGF2 FGFR4 GDNF GFAP NGF S100B

GO Terms for Neuroma

Cellular components related to Neuroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 9.46 ANK3 CALCA NF2 TRPV1
2 axon GO:0030424 9.26 ANK3 CALCA RET TGFB1
3 neuronal cell body GO:0043025 9.02 CALCA RET S100B TGFB1 TRPV1

Biological processes related to Neuroma according to GeneCards Suite gene sharing:

(show all 14)
id Name GO ID Score Top Affiliating Genes
1 positive regulation of cell proliferation GO:0008284 9.72 FGF2 FGFR4 GDNF S100B TGFB1
2 phosphatidylinositol-mediated signaling GO:0048015 9.67 FGF2 FGFR4 NGF
3 positive regulation of gene expression GO:0010628 9.65 ANK3 FGFR4 NGF RET TGFB1
4 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.54 GDNF TGFB1
5 negative regulation of DNA replication GO:0008156 9.52 NF2 TGFB1
6 negative regulation of blood vessel endothelial cell migration GO:0043537 9.51 FGF2 TGFB1
7 hyaluronan catabolic process GO:0030214 9.48 FGF2 TGFB1
8 detection of temperature stimulus involved in sensory perception of pain GO:0050965 9.46 CALCA TRPV1
9 negative regulation of cell-cell adhesion GO:0022408 9.43 NF2 TGFB1
10 lens fiber cell differentiation GO:0070306 9.4 NF2 TGFB1
11 enteric nervous system development GO:0048484 9.37 GDNF RET
12 MAPK cascade GO:0000165 9.35 FGF2 FGFR4 GDNF RET TGFB1
13 ureteric bud development GO:0001657 9.33 GDNF RET TGFB1
14 response to pain GO:0048265 8.8 CALCA RET TRPV1

Molecular functions related to Neuroma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 FGF2 GDNF NGF TGFB1
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 8.92 FGF2 FGFR4 GDNF RET

Sources for Neuroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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