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NIID
MCID: NRN008
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Neuronal Intranuclear Inclusion Disease (NIID) malady |
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Sources: 39NIH Rare Diseases, 43OMIM, 29MalaCards See all sources Fully expand this MalaCard Export this MalaCard |
NIH Rare Diseases:39 Neuronal intranuclear inclusion disease (niid) refers to a group of rare degenerative nerve diseases. signs and symptoms of niid are widespread, progressive, and usually begin in childhood. niid causes worsening of many of the body's activities, including balance, movement, talking, eating, and cognition. currently the cause of niid is not known. both sporadic and familial cases have been described.
MalaCards: Neuronal Intranuclear Inclusion Disease, also known as neuronal intranuclear hyaline inclusion disease, is related to transient cerebral ischemia and spinocerebellar ataxia type 3, and has symptoms including ataxia/incoordination/trouble of the equilibrium, movement disorder and speech troubles/aphasia/dysphasia/echolalia/mutism/logorrhea/dysprosodia. An important gene associated with Neuronal Intranuclear Inclusion Disease is RPS27A (ribosomal protein S27a), and among its related pathways are DNA damage Role of SUMO in p53 regulation and Signaling events mediated by HDAC Class II. The compounds pic 1 and thioflavin have been mentioned in the context of this disorder. Related mouse phenotypes are nervous system and mortality/aging. OMIM: |
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Sources: 39NIH Rare Diseases, 41Novoseek, 45Orphanet, 43OMIM, 56UMLS, 32MESH via Orphanet, 24ICD10 via Orphanet, 57UMLS via Orphanet See all sources |
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Sources: 43OMIM, 45Orphanet See all sources |
Clinical features from OMIM:Symptoms:45
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Sources: 5CenterWatch, 38NIH Clinical Center, 6ClinicalTrials, 56UMLS, 37NDF-RT See all sources |
Approved drugs:Search CenterWatch for neuronal intranuclear inclusion disease Drug clinical trials:Search ClinicalTrials for neuronal intranuclear inclusion disease Search NIH Clinical Center for neuronal intranuclear inclusion disease Search CenterWatch for neuronal intranuclear inclusion disease |
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Sources: 33MGI, 26inGenious Targeting Laboratory See all sources |
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Sources: 47PubMed See all sources |
Articles related to neuronal intranuclear inclusion disease:
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Sources: 16GeneCards, 42Novus Biologicals, 26inGenious Targeting Laboratory See all sources |
Genes related to neuronal intranuclear inclusion disease:(show all 14)
Products for genes related to neuronal intranuclear inclusion disease disease:
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Sources: 1BioGPS See all sources |
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Sources: 12EMD Millipore, 34NCBI BioSystems Database, 4Cell Signaling Technology See all sources |
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Sources: 41Novoseek, 55Tocris Bioscience, 11DrugBank, 46PharmGKB, 22HMDB See all sources |
Compounds related to neuronal intranuclear inclusion disease according to GeneCards/GeneDecks:(show all 25)
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Sources: 15Gene Ontology See all sources |
Cellular components related to neuronal intranuclear inclusion disease according to GeneCards/GeneDecks:
Biological processes related to neuronal intranuclear inclusion disease according to GeneCards/GeneDecks:(show all 8)
Molecular functions related to neuronal intranuclear inclusion disease according to GeneCards/GeneDecks:
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