Summaries for Neuronitis

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22MalaCards
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MalaCards: Neuronitis is related to carcinoma and prostatitis. An important gene associated with Neuronitis is CHRNA5 (cholinergic receptor, nicotinic, alpha 5 (neuronal)), and among its related pathways are cAMP Pathway and MAPK Signaling. The compounds serine and retinoic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, whole blood and lymph node, and related mouse phenotypes are growth/size and nervous system.

Aliases & Descriptions for Neuronitis

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6Disease Ontology, 8DISEASES, 43UMLS, 27NCIt
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Aliases & Descriptions:

neuronitis 6 8 43

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Related Diseases for Neuronitis

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13GeneCards, 14GeneDecks
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Diseases related to neuronitis by text searches and GeneDecks gene sharing:

(show top 50)    (show all 985)
idRelated DiseaseScoreTop Affiliating Genes
1carcinoma497.7ZNF148, ZNF384, PIK3CB, PIK3CD, PI4K2A, PIK3CA
2prostatitis493.8ZNF462, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PINK1
3leukemia482.7ZNF384, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
4pancreatitis446.8ZNF148, PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2
5alzheimer's disease398.3PIK3CB, PIK3CD, PI4K2A, PIK3CA, PINK1, PIK3R1
6colorectal cancer368.2PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
7adenocarcinoma359.8ZNF148, PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG
8neuroblastoma354.8ZNF423, PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3CG
9thyroiditis342.9PIK3CB, PIK3CA, PIP5K1C, PIK3R1, PICALM, PIK3C2A
10schizophrenia340.4PIK3CB, PIP5K1B, PIK3CA, PINK1, PIK3R1, PICK1
11melanoma337.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
12cerebritis332.0PIK3R1, PICK1, PIK3C2A, PIK3CG, LRP1, LRP2
13retinitis322.2ZNF513, PIK3CA, PIK3C2A, PIK3CG, PIM1, LRP1
14hypoxia311.4PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3C2A, PIK3CG
15ovarian cancer286.0PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R1, PIK3CG
16malaria280.3ZNF259, PI4KB, PIK3C3, PIM1, LRP1, KLF4
17cholesterol276.9ZNF259, PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1
18ischemia240.6PIK3CA, PIK3C2A, PIK3CG, KLF4, NDFIP1, NCAM1
19hypertension238.9PIK3CB, PIK3R1, PIK3C2B, PIK3C2A, PIK3CG, PIM1
20cervicitis238.1ZNF384, PIK3CA, PIK3CG, PIN1, NCL, PDE4A
21arthritis236.0ZNF395, PIK3CD, PIK3CG, PIN1, LRP1, LRP2
22breast carcinoma227.4PIK3CA, PIK3R1, PIK3CG, LRP1, LRPAP1, SH3GL2
23fibrosis225.6PIK3CA, PIK3CG, PIN1, LRP1, KLF6, NCF2
24adenoma222.4PIK3CA, KLF4, NCAM1, NCF2, NCOA1, NCOR1
25obesity219.1PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, LRP1
26rheumatoid arthritis211.3PIK3CD, PIK3CG, PIN1, LRP1, LRP2, SH2D1A
27sarcoma208.3ZNF395, ZNF384, PIK3CB, PIK3CD, PIK3CA, PIK3R2
28hepatocellular carcinoma203.4ZNF148, ZNF384, PIK3CB, PIK3CD, PI4K2A, PIK3CA
29multiple sclerosis198.5PINK1, LRP1, SH3GL2, KLC1, NCAM1, NCKAP1
30ataxia198.1ZNF423, PIP5K1B, PIK3CA, PIK3R1, PICK1, PIK3CG
31diabetes mellitus193.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
32gastric cancer191.2ZNF148, PIK3CB, PIK3CA, PIK3R1, PIK3CG, PIN1
33atherosclerosis185.4PIK3C2A, PIK3CG, LRP1, LRP2, LRP6, LRP8
34astrocytoma177.8PIK3CA, PIK3R1, PIK3CG, LRP1, KLF6, NCAM1
35neurodegeneration175.8ZNF746, ZNF259, PIK3CB, PINK1, PIK3CG, PIN1
36asthma174.2PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3CG, PIN1
37colon cancer167.8PIK3CB, PIK3CA, PIK3R3, PIK3R1, PIK3CG, LRP6
38dementia165.9PINK1, PIK3C2A, PIK3CG, PIN1, LRP1, LRP8
39neuropathy163.0PICALM, PIK3C2A, NCAM1, PDE3B, PDE4A, REN
40squamous cell carcinoma160.1PIK3CB, PIK3CA, PIN1, PIM1, KLF4, NCL
41lupus erythematosus157.7ZNF423, PIK3CD, PIK3C2A, PIK3CG, LRP2, NCF2
42gonococcal synovitis157.0PIK3CB, PIK3CA, PIK3R1, PIK3CG, LRP1, KLF4
43lateral sclerosis156.9ZNF746, CNR1, CNR2, CNTF, CNTFR, CNTN4
44lung carcinoma156.2PIK3CA, PIK3R1, PIK3CG, KLF6, NCAM1, RECK
45amyotrophic lateral sclerosis153.6ZNF746, CNR1, CNR2, CNTF, CNTFR, CNTN4
46esophagitis153.4PIK3CB, PIK3CA, PIK3C2A, PIK3CG, PIN1, PIK3C3
47bipolar disorder152.6PIP4K2A, PIK3C3, RFX2, NCAM1, NCAN, NCOR2
48seizures151.8PIK3C2A, NCDN, PDCD10, CNP, CNR1, CNTF
49retinoblastoma151.0PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3CG, KLF6
50pneumonia144.1PIK3C2A, PDE4A, RELA, CNDP1, CNNM1, CNNM2

Graphical network of the top 20 diseases related to neuronitis:



Graphical network of diseases related to neuronitis

Clinical Features for Neuronitis

Drugs & Therapeutics for Neuronitis

Sources:
4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Neuronitis

Anatomical Context for Neuronitis

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22MalaCards
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MalaCards organs/tissues related to neuronitis:

22
Bone marrow, Whole blood, Lymph node, Thymus, Brain, Cortex, Cerebellum, Retina, Spinal cord, Heart, Smooth muscle, Skeletal muscle, Small intestine, Colon, Adipocyte, Kidney, Liver, Lung, Pancreas, Thyroid, Salivary gland, Adrenal gland, Breast, Skin, Ovary, Placenta, Prostate, Testis, Cervix, Myeloid, Monocytes, Nk cells, T cells, B lymphoblasts, B cells, Endothelial, Fetal brain, Prefrontal cortex, Cingulate cortex, Parietal lobe, Temporal lobe, Occipital lobe, Ciliary ganglion, Globus pallidus, Olfactory bulb, Thalamus, Hypothalamus, Subthalamic nucleus, Caudate nucleus, Amygdala, Pons, Medulla oblongata, Sup cervical ganglion, Dorsal root ganglion, Trigeminal ganglion, Cardiac myocytes, Tongue, Fetal liver, Fetal lung, Trachea, Bronchial epithelium, Fetal thyroid, Pancreatic islet, Adrenal cortex, Pineal, Pituitary, Testis germ, Testis leydig

Phenotypes for genes affiliated with Neuronitis

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25MGI
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MGI Mouse Phenotypes related to neuronitis:

25 (show all 30)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1growth/size phenotypeMP:0005378INFZNF148, ZNF384, ZNF423, ZNF238, PIK3CB, PI4K2A
2nervous system phenotypeMP:0003631INFZNF148, ZNF423, ZNF238, PI4K2A, PIP5K1C, PICK1
3homeostasis/metabolism phenotypeMP:0005376INFZNF148, ZNF423, PIK3CB, PIK3CD, PI4K2A, PIK3CA
4muscle phenotypeMP:0005369INFPIK3CA, PIK3R2, PIK3R1, PIK3CG, PIK3C3, LRP1
5vision/eye phenotypeMP:0005391INFPIK3CA, PIN1, LRP2, LRP6, NCAM1, NCDN
6respiratory system phenotypeMP:0005388INFZNF423, LRP4, LRP2, LRP6, NDFIP1, NDN
7hematopoietic system phenotypeMP:0005397INFPIP5K1B, PIP5K1C, PIP5K1A, PICALM, PIM1, SH2B2
8cardiovascular system phenotypeMP:0005385INFZNF148, PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIP5K1C
9other phenotypeMP:0005395INFLRPAP1, KLC1, RECK, RELB, CNR1,
10limbs/digits/tail phenotypeMP:0005371INFLRP4, LRP6, NDFIP1, RFNG, RECK, RELA
11craniofacial phenotypeMP:0005382INFZNF423, LRP4, LRP2, LRP6, KLF4, RFNG
12pigmentation phenotypeMP:0001186INFPDE3B, KIT, KITLG, VSX2, , RB1
13no phenotypic analysisMP:0003012INFPIK3CD, PINK1, PIK3R1, PIK3C2B, LRP2, LRP6
14mortality/agingMP:0010768INFZNF148, ZNF423, ZNF238, ZNF259, PIK3CB, PI4K2A
15renal/urinary system phenotypeMP:0005367INFPI4K2A, LRP4, LRP2, LRP6, LRPAP1, NCK1
16tumorigenesisMP:000200680.3PIK3CB, PIK3CA, PIK3R2, PIK3R1, KLF4, NCSTN
17taste/olfaction phenotypeMP:000539429.5ZNF423, NCAM2, PDE1C, PDE4A, CNGA2, CNGA3
18integument phenotypeMP:0010771INFZNF148, PIK3C2B, PIK3CG, PIN1, LRP4, LRP6
19reproductive system phenotypeMP:0005389INFZNF148, ZNF384, PI4K2A, PIP5K1B, PIK3CA, PIP5K1A
20digestive/alimentary phenotypeMP:0005381INFZNF148, LRP2, LRP6, KLF4, RFNG, NCKAP1
21adipose tissue phenotypeMP:0005375INFPIK3CA, PIK3R1, PIK3C2A, LRP1, LRP6, NCOR1
22skeleton phenotypeMP:0005390INFZNF384, PIK3CD, PIK3CG, LRP4, LRP1, LRP2
23endocrine/exocrine gland phenotypeMP:0005379INFZNF148, ZNF384, PIP5K1B, PINK1, PIP5K1A, PICK1
24embryogenesis phenotypeMP:0005380INFZNF148, ZNF259, PIK3CB, PIK3CA, PIP5K1C, PICALM
25normal phenotypeMP:0002873INFZNF148, ZNF423, PI4K2A, PIK3R1, PIP5K1A, PIK3C3
26liver/biliary system phenotypeMP:0005370INFPICALM, PIK3C3, LRP6, KLF6, NDFIP1, NCOR1
27hearing/vestibular/ear phenotypeMP:0005377INFLRP2, LRP6, LRRC4, KIT, KITLG, RDX
28behavior/neurological phenotypeMP:0005386INFZNF423, PI4K2A, PIK3CA, PINK1, PIP5K1C, PIK3C3
29immune system phenotypeMP:0005387INFZNF148, PIK3CD, PIP5K1B, PINK1, PIP5K1C, PICALM
30cellular phenotypeMP:0005384INFZNF148, ZNF423, ZNF238, ZNF259, PIK3CB, PIK3CD

Publications for genes affiliated with Neuronitis

Sources:
35PubMed
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Articles related to neuronitis:

(show top 50)    (show all 11021)
idTitleAuthorsYearAffiliating Genes
1Impaired mitochondrial dynamics and abnormal interact ion of amyloid beta with mitochondrial protein Drp1 in neurons from patients wi th Alzheimer's disease: implications for neuronal damage. (21459773)Manczak M.... Reddy P.H.2011APP, DNM1L
2Nucleocytoplasmic Cdk5 is involved in neuronal cell cycle and death in post-mitotic neurons. (21415596)Zhang J.... Herrup K.2011CDK5
3Dendritic spine alterations in neocortical pyramidal neurons following postnatal neuronal Nogo-A knockdown. (20938157)Pradhan A.D.... Kartje G.L.2010RTN4
4Neuronal isoforms of Src, Fyn and Lck tyrosine kinas es: A specific role for p56lckN in neuron protection (20176329)Rouer E.2010LCK, FYN
5Neuronal RNA granule contains ApCPEB1, a novel cytopl asmic polyadenylation element binding protein, in Aplysia sensory neuron. (19887896)Chae Y.S.... Kaang B.K.2010CPEB1
6Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis. (19801631)Wang X.... Mao Z.2009MEF2D
7Atoh1-lineal neurons are required for hearing and for the survival of neurons in the spiral ganglion and brainstem accessory auditor y nuclei. (19741118)Maricich S.M.... Zoghbi H.Y.2009ATOH1
8Postmitotic specification of Drosophila insulinergic neurons from pioneer neurons. (18336071)Miguel-Aliaga I.... Gould A.P.2008RLN3
9Neuronal activity enhances aryl hydrocarbon receptor-mediated gene expression and dioxin neurotoxicity in cortical neurons. (17973980)Lin C.H.... Lee Y.H.2008CAMK4
10Neuronal injury-inducible gene is synergistically regulated by ATF3, c-Jun, and STAT3 through the interaction with Sp1 in damaged neurons. (18192274)Kiryu-Seo S.... Kiyama H.2008JUN, STAT3, ATF3
11Neuronal somatic ATP release triggers neuron-satellite glial cell communication in dorsal root ganglia. (17525149)Zhang X.... Huang L.Y.2007P2RX7
12Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons. (17463094)Lobsiger C.S.... Cleveland D.W.2007SOD1
13A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival. (17522300)Meikle L.... Kwiatkowski D.J.2007TSC1, TSC2
14Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons. (16914688)Zhang H.... Bassell G.J.2006SMN1, GEMIN2
15Underediting of GluR2 mRNA, a neuronal death inducing molecular change in sporadic ALS, does not occur in motor neurons in ALS1 or SBMA. (16225946)Kawahara Y.... Kwak S.2006SOD1, GRIA2
16Increased cerebrospinal fluid and serum levels of S100B in first-onset schizophrenia are not related to a degenerative release of glial fibrillar acidic protein, myelin basic protein and neurone-specific enolase from glia or neurones. (17043297)Steiner J.... Wunderlich M.T.2006S100B, MBP
17A histopathological study of premature and mature infants with pontosubicular neuron necrosis: neuronal cell death in perinatal brain damage. (16712812)Takizawa Y.... Itoh M.2006BCL2, BCL2L1, GFAP
18Neuronal-specific roles of the survival motor neuron protein: evidence from survival motor neuron expression patterns in the developing human central nervous system. (16651888)Giavazzi A.... Battaglia G.2006SMN1
19Ubiquitin immunohistochemistry suggests classic motor neuron disease, motor neuron disease with dementia, and frontotemporal dementi a of the motor neuron disease type represent a clinicopathologic spectrum. (16106222)Mackenzie I.R.... Feldman H.H.2005RPS27A
20Neuron-restrictive silencer factor regulates the N-methyl-D-aspartate receptor 2B subunit gene in basal and ethanol-induced gene expression in fetal cortical neurons. (15755907)Qiang M.... Ticku M.K.2005GRIN2B, REST
21Neuronal cell death induced by cystatin C in vivo and in cultured human CNS neurons is inhibited with cathepsin B. (16325785)Nagai A.... Kim S.U.2005CST3
22Quantification of NGF-dependent neuronal differentiation of PC-12 cells by means of neurofilament-L mRNA expression and neuronal outgrowth. (15488244)Schimmelpfeng J.... Dertinger H.2004NEFL
23Survival motor neuron SMN1 and SMN2 gene promoters: identical sequences and differential expression in neurons and non-neuronal cells. (15162126)Boda B.... Simonneau M.2004SMN1, SMN2
24Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures. (15485497)de Bernardo S.... Mena M.A.2004MAPK14, NOS2, LOX
25Interleukin-6 produces neuronal loss in developing cerebellar granule neuron cultures. (15342195)Conroy S.M.... Gruol D.L.2004IL6
26Localization of wild-type and mutant neuronal ceroid lipofuscinosis CLN8 proteins in non-neuronal and neuronal cells. (15160397)Lonka L.... Jalanko A.2004CLN8
27RPGRIP1s with distinct neuronal localization and biochemical properties associate selectively with RanBP2 in amacrine neurons. (12874105)Castagnet P.... Ferreira P.2003RPGRIP1, RPGR
28Striatal neurons but not nigral dopaminergic neurons in neonatal primary cell culture express endogenous functional N-methyl-D-aspartate receptors. (14667572)Lui P.W.... Yung K.K.2003GRIN1, GRIN2B, GRIN2A
29Neuronal thread protein regulation and interaction with microtubule-associated proteins in SH-Sy5y neuronal cells. (14685691)de la Monte S.M.... Wands J.R.2003IGF1
30The thrombospondin type 1 repeat (TSR) and neuronal differentiation: roles of SCO-spondin oligopeptides on neuronal cell types and cell lines. (14692680)Meiniel A.... Dastugue B.2003SSPO
31Expression of the high-affinity choline transporter, CHT1, in the neuronal and non-neuronal cholinergic system of human and rat skin. (12406342)Haberberger R.V.... Kummer W.2002SLC5A7
32Reduced neuronal nitric oxide synthase (NOS1) antigen in sacral motor neurones in motor neurone disease. (12200626)Baxter R.G.... Pullen A.H.2002NOS1
33Cell lines derived from hippocampal neurons of the normal and trisomy 16 mouse fetus (a model for Down syndrome) exhibit neuronal markers, cholinergic function, and functional neurotransmitter receptors. (12429219)CA!rdenas A.M.... Caviedes P.2002SYP, MAP2
34Neuron-specific Bcl-2 homology 3 domain-only splice variant of Bak is anti-apoptotic in neurons, but pro-apoptotic in non-neuronal cells. (11278671)Sun Y.F.... Arumae U.2001BAK1
35Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons. (11509947)Hayashi K.... Sakai N.2001HGF
36A study of survival motor neuron and neuronal apoptosis inhibitory protein gene in spinal muscular atrophy (11798607)Zhang L.... Xiao B.2001SMN1, NAIP
37Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. (11264300)Hartmann A.... Hirsch E.C.2001CASP8
38Inhibition of neuronal nitric-oxide synthase by calcium/ calmodulin-dependent protein kinase IIalpha through Ser847 phosphorylation in NG108-15 neuronal cells. (10874031)Komeima K.... Watanabe Y.2000PRKACA, PRKCA, NOS1
39The survival motor neuron protein of Schizosacharomyces pombe. Conservation of survival motor neuron interaction domains in divergent organisms. (10816558)Paushkin S.... Dreyfuss G.2000SMN1
40Endogenous and exogenous fibroblast growth factor 2 support survival of chick retinal neurons by control of neuronal neuronal bcl-x(L) and bcl-2 expression through a fibroblast berowth factor receptor 1- and ERK-dependent pathway. (10854258)DAcsirAc L.... Jeanny J.C.2000FGFR1, FGF2, BCL2L1
41Neuronal pentraxin receptor, a novel putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2 and taipoxin-associated calcium-binding protein 49. (9261167)Dodds D.C.... Perin M.S.1997RCN2, NPTX2, NPTX1
42Distinct effects of recombinant tenascin-R domains in neuronal cell functions and identification of the domain interacting with the neuronal recognition molecule F3/11. (9081628)Xiao Z.C.... Schachner M.1996CNTN1, TNR
43Intraventricular administration of nitric oxide synth ase inhibitors prevents delayed neuronal death in gerbil hippocampal CA1 neuron s. (8584229)Kohno K.... Sakaki S.1995NOS1
44Long-term bFGF neuronal culture: reintroduction into serum medium yields neurons and non-neuronal cells with neuronal characteristics. (7478215)Eubanks J.H.... Jones O.T.1995NUDT6
45NMDA-mediated toxicity to striatal neurons is not rev ersed by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase. (8821044)LAPschmann P.A.... Klockgether T.1995NOS1
46Immunologic localization and kinetic characterization of a Na+/Ca2+ exchanger in neuronal and non-neuronal cells. (7834362)Michaelis M.L.... Kwong W.H.1994SLC8A1
47Neurotransmitter properties of guinea-pig sympathetic neurons grown in dissociated cell culture--II. Fetal and embryonic neurons: regulation of neuropeptide Y expression. (7906017)Matsumoto S.G.... Kreulen D.L.1993TH, NPY, SST
48Ectopic trkA expression mediates a NGF survival response in NGF-independent sensory neurons but not in parasympathetic neurons. (8253850)Allsopp T.E.... Davies A.M.1993HCLS1
49Human cortical neuronal cell line: a model for HIV-1 infection in an immature neuronal system. (8318271)Truckenmiller M.E.... Sweetnam P.M.1993ITIH4
50Non-neuronal 210 x 10(3) Mr microtubule-associated protein (MAP4) contains a domain homologous to the microtubule-binding domains of neuronal MAP2 and tau. (1905296)Chapin S.J.... Bulinski J.C.1991MAPT, MAP2, MAP4

Expression for genes affiliated with Neuronitis

Sources:
1BioGPS
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Expression patterns in normal tissues for genes affiliated with Neuronitis

Pathways for genes affiliated with Neuronitis

Sources:
36QIAGEN, 20KEGG, 3Cell Signaling Technology, 10EMD Millipore, 41Thomson Reuters
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Pathways related to neuronitis according to GeneDecks:

(show top 50)    (show all 485)
idPathwayScoreTop Affiliating Genes
1cAMP Pathway3678.5PIK3R3, PIK3R2, PIK3R1, PDE1A, PDE1B, PDE1C
2MAPK Signaling3665.2PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
3ERK Signaling3662.3PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
4Antioxidant Action of Vitamin-C3655.6NCF2, NCF4, KIT, KITLG, SEMA3A, VEGFB
5Phospholipase-C Pathway3654.5KIT, KITLG, SEMA3A, VEGFB, BMP1, BMP2
6GPCR Pathway3651.6PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, SEMA3A
7Breast Cancer Regulation by Stathmin13649.6PIK3R3, PIK3R2, PIK3R1, RB1CC1, SEMA3A, VEGFB
8eNOS Signaling3647.4PIK3R3, PIK3R2, PIK3R1, CNGA1, CNGA4, CNGB1
9JAK-STAT Pathway3647.2PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, RBX1
10Tec Kinases Signaling3646.6PIK3R3, PIK3R2, PIK3R1, WAS, KITLG, SEMA3A
11Pathways in cancer2045.1PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
12MAPK Family Pathway3644.2PIK3R3, PIK3R2, PIK3R1, KITLG, SEMA3A, BRAF
13Pancreatic Adenocarcinoma3643.2PIK3R3, PIK3R2, PIK3R1, KIT, KITLG, RB1
14Transendothelial Migration of Leukocytes3643.0PIK3R3, PIK3R2, PIK3R1, NCF2, NCF4, WAS
15GnRH Signaling3641.3BRAF, RAC3, RAF1, RAC1, RAC2, PAK1
16IP3 Pathway3640.2PIK3R3, PIK3R2, PIK3R1, KITLG, SEMA3A, VEGFB
17WNT Signaling3637.1LRP6, REST, BTRC, VIM, MYC, RAC1
18Paxillin Interactions3637.0PIK3R3, PIK3R2, PIK3R1, NCK1, KIT, KITLG
19Endothelin-1 Signaling Pathway3636.9PIK3R3, PIK3R2, PIK3R1, KIT, BRAF, LMTK2
20TGF-Beta Pathway3636.2PIK3R3, PIK3R2, PIK3R1, KITLG, SEMA3A, VEGFB
21Cytoskeletal Signaling336.1NCK1, WAS, WASF3, WASL, KIF3A, RDX
22Rac1 Pathway3636.0PIP5K1B, PIK3R3, PIK3R2, PIP5K1C, PIK3R1, PIP5K1A
23JNK Pathway3635.7PIK3R1, KIT, KITLG, VEGFB, LMTK2, BMP1
24Focal adhesion2033.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIP5K1C
25Thrombin Signaling3631.7PIK3R3, PIK3R2, PIK3R1, MYLK, RAF1, MRAS
26Neurotrophin signaling pathway2031.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3CG
27Regulation of actin cytoskeleton2030.6PIK3CD, PIP5K1B, PIK3R3, PIK3R2, PIP5K1C, PIK3R1
28Endocytosis2028.6PIP5K1B, PIP5K1C, PIP5K1A, SH3GL1, SH3GL2, SH3GL3
29Melanogenesis2028.5KIT, KITLG, RAF1, LEF1, FZD1, FZD10
30ITK and TCR Signaling3628.2PIK3R3, PIK3R2, PIK3R1, NCK1, NCK2, WAS
31Aldosterone Signaling in Epithelial Cells3627.9PIP5K1B, PIK3R3, PIK3R2, PIP5K1C, PIK3R1, PIP5K1A
32Transcription CREB pathway1027.3PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
33PDGF Pathway3626.0PIK3R3, PIK3R2, PIK3R1, WASL, VAV2, RAF1
34Actin-Based Motility by Rho Family GTPases3626.0PIP5K1B, PIP5K1C, PIP5K1A, WASF1, WASL, SEMA3A
35Glioblastoma Multiforme3625.4PIK3R3, PIK3R2, PIK3R1, RB1, BRAF, RAF1
36Calcium channels1025.1CHRND, CHRNA6, CHRNA7, CHRNA3, CHRNB2, CHRNA4
37Germ Cell-Sertoli Cell Junction Dynamics3624.1PIK3R3, PIK3R2, WAS, VCL, RAC3, RAC1
38PI3K Signaling in B-Lymphocyte3623.9PIK3R3, PIK3R1, PIK3C2B, PIK3C2G, PIK3C2A, PIK3C3
39Transcription_Androgen Receptor nuclear signaling4122.9NCOA1, NCOR1, RAF1, FZD1, FZD10, FZD2
40Development_Endothelin-1/EDNRA signaling4121.5RAC1, CDC42, ITPR1, ITPR2, ITPR3, GRB2
41Immune response IL-2 activation and signaling pathway1021.4PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, REL
42CCKBR-Gastrin Stimulated Signaling3621.3RAF1, BCAR1, ATF2, JUN, FOS, MEF2C
43Development_Endothelin-1/EDNRA transactivation of EGFR4121.1PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
44Development_GDNF family signaling4120.8PIK3CB, PIK3CA, PIK3R2, PIK3R1, NCK1, RELA
45Development IGF-RI signaling1020.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R1, REL
46Immune response_CD16 signaling in NK cells4120.4PIK3CD, PIK3R3, PIK3R2, PIK3R1, PIP5K1A, WAS
47Development Prolactin receptor signaling1020.3PIK3CB, PIK3CD, PIK3CA, PIK3R2, PIK3R1, RELA
48Signal transduction PTEN pathway1019.8PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
49ErbB2-ErbB3 Heterodimers3619.1PIK3R3, PIK3R2, PIK3R1, RAF1, BAD, MRAS
50Development EGFR signaling pathway1010.5CBL

Compounds for genes affiliated with Neuronitis

Sources:
32Novoseek , 42Tocris Bioscience, 18HMDB, 34PharmGKB, 9DrugBank
See all sources

Compounds related to neuronitis according to GeneDecks:

(show top 50)    (show all 390)
idCompoundScoreTop Affiliating Genes
1serine32 INFPIK3CB, PIK3CD, PIK3CA, PINK1, PIK3R1, PICK1
2retinoic acid32 42 18 129.2PIK3CA, PIK3CG, LRP1, LRP2, NDN, RFX1
3glutamate32 120.2PIK3CB, PI4K2A, PIK3CA, PIK3R1, NCAM1, NCOA1
4estrogen32 103.0PIK3CB, PIK3R1, KLF6, NCL, NCOA1, NCOR1
5dexamethasone32 42 34 9 9 105.8PIK3CA, PIK3R1, LRP1, LRPAP1, NCAM1, PDE4A
6vegf32 101.4PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, LRP1
7forskolin32 42 9 9 77.9PIK3R1, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C
8h2o232 71.9PIK3CB, PIK3R1, PIK3CG, NCF2, PDE4A, SGCB
9potassium32 9 18 9 73.7PIK3CA, PIK3C2A, NCAM1, NCS1, PDE3B, PDE4A
10norepinephrine32 9 18 9 67.6PIK3C2A, PDE4A, REN, RETN, CNR1, CNTF
11wortmannin32 42 63.5PIK3CB, PIK3CD, PIK3CA, PIK3R1, PIK3C2B, PIK3C2G
12gaba32 42 59.5NCAM1, RELN, CNR1, CNTF, GCG, VIM
13heparin32 9 18 9 59.4PIK3CA, PIK3C2A, PIK3CG, LRP1, LRP2, LRPAP1
14paclitaxel32 34 9 9 53.8PIK3CA, PIK3CG, PIN1, NCL, KIT, KITLG
15butyrate32 49.0ZNF148, KLF4, NCF2, NCOA1, RET, KITLG
16phospholipid32 46.0PIK3R1, LRP2, LRP8, PDE4A, VTI1B, RCVRN
17etoposide32 42 9 9 43.3PIK3CB, PIK3CA, PIK3R1, PIK3CG, RECK, CNTN2
18ly29400232 40.0PIK3CB, PIK3CA, PIK3R1, PIK3C2A, PIK3CG, RET
19ascorbic acid32 18 39.0PIK3CG, SGCB, CNTF, PCNA, GCH1, SETD2
20acth32 36.6PIK3C2A, PDE3B, REN, PCSK2, PCSK1, SERPINA1
21sucrose32 9 18 9 38.8LRP1, LRP2, LRPAP1, RECK, CNP, PCSK2
22phosphatidylcholine32 34.8PIK3CB, CNR1, SELE, VIM, VIP, LPL
23curcumin32 34.7PIK3CG, NAT1, VEGFA, MYC, RAF1, BID
24isoproterenol32 9 9 35.6PIK3R3, PIK3R2, PIK3R1, PDE3A, PDE3B, PDE4A
25bromodeoxyuridine32 33.2PIK3CA, PIK3R1, NCAM1, CNP, CNTF, CNTN2
26quercetin32 42 9 18 9 36.5PIK3CB, PIK3CD, PIK3CA, PIK3R3, PIK3R2, PIK3R1
27resveratrol32 9 18 9 35.2PIK3CA, PIK3CG, PCNA, RB1, BSG, BRCA1
28catecholamine32 31.8PIK3C2A, PDE4A, REN, RET, CNTF, GCH1
29imatinib32 34 9 9 33.8PIK3CA, PIK3R1, PIK3CG, RET, KIT, KITLG
305-aza-2deoxycytidine32 29.9KITLG, SFRP1, PCNA, SEMA3B, VIM, BRCA1
31inositol32 29.5PIK3CB, PIK3CD, SH2D1A, PDE4A, LPL, RASA2
32phorbol32 29.2NCF2, REL, VAMP2, MYC, MYB, RAP1A
334-aminopyridine32 42 27.1SGCB, CNR1, VIM, KCNA5, KCNA7, KCNAB1
34sodium nitroprusside32 25.2PIK3C2A, PDE2A, PDE4A, REN, SGCB, PCNA
35simvastatin32 34 42 9 18 9 30.1PIK3C2A, KITLG, SELE, SELP, SERPINE1, VEGFA
36peroxynitrite32 23.7SGCB, PC, SERPINA1, SEPP1, NAT1, PARP1
37pdtc32 23.3PIK3CA, PIK3CG, GCLC, GCLM, SELE, SETD2
38lithium32 34 9 18 9 27.1PIK3R1, REN, BDNF, SCG2, MUC1, XBP1
39gemcitabine32 34 9 9 24.5PCNA, BRCA1, VEGFA, BNIP3, MYC, BID
40azathioprine32 34 9 9 24.5PCNA, VIM, MYOD1, BMP2, BMP4, RARB
41bortezomib32 9 9 23.5SETD2, BRCA1, VEGFA, VCP, MYC, BID
42diphenyleneiodonium32 21.4NCF2, SETD2, SERPINF1, VEGFA, RAC1, XDH
43gefitinib32 34 9 9 24.3PIK3CA, PIK3CG, KIT, GCG, SELP, VIM
44egcg32 21.3PIK3CG, RAF1, BCL2L1, CHUK, LDLR, XIAP
45prednisolone32 9 9 23.2PIK3C2A, KITLG, VIP, MYC, BMP6, CHKB
46p00332 20.5RETN, KIT, RB1, SERPINA1, SERPINE1, BRCA1
47adenine32 9 18 9 INFPDE3B, RET, SETD2, NAT1, NAT2, BRAF
48lipid32 INFPIK3CB, PIK3CD, PIP5K1B, PIK3CA, PIK3R1, PIK3C2B
49phosphatidylserine32 9 9 INFRECK, SELE, VIM, LPL, LMNB1, RAC1
50Adenosine triphosphate9 18 9 INFPIK3CB, PIK3CD, PIP5K1B, PIK3CA, PINK1, PIP5K1C

GO Terms for genes affiliated with Neuronitis

Sources:
12Gene Ontology
See all sources

Cellular components related to neuronitis according to GeneDecks:

(show all 40)
idNameGO IDScoreTop Affiliating Genes
1nucleusGO:005634INFZNF395, ZNF536, ZNF462, ZNF148, ZNF513, ZNF746
2membraneGO:016020INFPIP5K1B, PIK3C2G, PIK3CG, LRRC4C, SH2B1, NCF4
3integral to plasma membraneGO:005887INFPI4K2A, LRP1, NCSTN, RET, SGCB, CNGA1
4cytosolGO:005829INFPIK3CB, PIK3CD, PI4K2A, PIP5K1B, PIK3CA, PIK3R3
5perinuclear region of cytoplasmGO:048471INFPICK1, PICALM, PI4KB, NDFIP1, NCS1, PDE2A
6extracellular spaceGO:005615INFLRP2, RELN, REN, CNP, CNTF, KIT
7plasma membraneGO:005886INFPIK3CD, PIK3R1, PIK3C2B, PIP5K1A, PICK1, PIEZO1
8integral to membraneGO:016021281.1PINK1, PIEZO2, PIEZO1, LRFN1, LRFN3, LRFN4
9nucleoplasmGO:00565482.4PIN1, WDR12, NCOA1, NCOR1, NCOR2, REL
10cell junctionGO:03005459.1PICK1, LRFN1, LRFN3, LRRC4B, LRFN2, LRRC4
11neuronal cell bodyGO:04302547.8PI4K2A, KLHL17, NCDN, PDE1B, CNKSR2, CNTF
12cell surfaceGO:00998644.8LRP6, LRPAP1, NCAM1, CNTN2, CNTNAP2, KISS1R
13postsynaptic membraneGO:04521143.0PICALM, LRFN1, LRFN3, LRFN2, LRRC4, KLHL17
14dendriteGO:03042538.9PI4K2A, LRFN3, NCDN, RELN, CNR2, CNTNAP2
15axonGO:03042437.0LRFN3, KLC1, KLHL24, NCDN, NCS1, CNTF
16microtubuleGO:00587435.8LRRC49, KLC1, KLC2, KLC3, KLC4, NDE1
17protein complexGO:04323430.7PICK1, SH3GLB1, KLC2, GCHFR, GCH1, SET
18neuron projectionGO:04300530.6PI4K2A, KLC2, KLC3, CNKSR2, KIF5B, KIF1B
19apical plasma membraneGO:01632429.7LRP2, SEPT7, VAMP3, RAB27B, RAB27A, RAPGEF4
20transcription factor complexGO:00566729.6KLF4, RFX3, RELA, RBL2, BSX, NAA15
21postsynaptic densityGO:01406928.5PICK1, LRFN1, KLHL17, NCS1, LPHN1, MYLK2
22membrane raftGO:04512127.5PI4K2A, SGCA, SELE, BSG, RAB5A, CLN3
23synapseGO:04520226.3PICK1, VAMP3, RASGRP2, PACSIN1, BCAN, UNC13B
24basolateral plasma membraneGO:01632325.9CNNM2, NAIP, RAPGEF4, LIN7B, LIN7A, LIN7C
25voltage-gated potassium channel complexGO:00807625.8CNTN2, CNTNAP1, CNTNAP2, KCNA10, KCNA3, KCNA5
26growth coneGO:03042623.9BOC, MYO5A, RAC3, RASGRF1, PAFAH1B1, PAK1
27lamellipodiumGO:03002721.6PIK3CA, PIP5K1A, WASF1, WASL, RDX, MYLK
28cell-cell junctionGO:00591121.5SGCA, CNN2, KIRREL, PCDH1, PCDH12, VCL
29dendritic spineGO:04319720.1SEZ6, LPAR1, RAPGEF4, PALM, KCND2, MTMR2
30synaptic vesicleGO:00802120.0SEPT5, BRSK1, MYLK2, RAB3B, RAB3A, RAB3C
31perikaryonGO:04320419.2KLHL24, NDN, CNR2, CNTNAP2, CLCN2, PAM
32sarcolemmaGO:04238319.2SGCA, SGCB, BSG, CLCN1, KCNQ1, KCND3
33presynaptic membraneGO:04273418.7PICK1, PICALM, LRFN3, LRRC4B, PDE2A, PCDH8
34terminal buttonGO:04319518.4MYLK2, P2RX2, P2RX3, P2RX7, GRIA2, GRIA3
35caveolaGO:00590118.2LRP6, LRP8, SELE, BMPR1A, CLN3, KCNA5
36Golgi apparatusGO:005794INFZNF148, PICK1, PICALM, PIK3C2A, LRP2, COG3
37endosomeGO:005768INFPI4K2A, PI4KB, LRP2, KIF16B, , RABEP1
38endoplasmic reticulumGO:005783INFPIK3C2B, PIEZO1, LRP2, LRP6, LRPAP1, NCK1
39cytoplasmGO:005737INFZNF395, ZNF746, ZNF259, PIP5K1A, PICK1, PIK3C2A
40extracellular regionGO:005576INFLRP8, LRPAP1, NDFIP1, RFNG, NCAM1, NCAN

Biological processes related to neuronitis according to GeneDecks:

(show top 50)    (show all 105)
idNameGO IDScoreTop Affiliating Genes
1in utero embryonic developmentGO:001701INFNCKAP1, KIDINS220, PCNT, LMX1B, BMP2, BMPR1A
2central nervous system developmentGO:007417INFSH3GL1, SH3GL2, SH3GL3, NDN, NCKAP1, RELN
3signal transductionGO:007165110.0ZNF259, PIK3CB, PIK3CD, PIP5K1A, PI4KB, LRP8
4synaptic transmissionGO:00726891.2PICK1, NCALD, CNP, KIF5A, PCDH8, PCDHB11
5positive regulation of transcription from RNA polymerase II promoterGO:04594480.6ZNF462, ZNF148, LRP6, KLF4, KLF6, RFX3
6axon guidanceGO:00741161.1PIP5K1C, SH3GL2, NCAM1, NCAN, NCK1, NCK2
7positive regulation of transcription, DNA-dependentGO:04589358.9ZNF711, ZNF423, ZNF326, PICALM, LRP6, KLF4
8negative regulation of transcription from RNA polymerase II promoterGO:00012257.0ZNF148, ZNF238, LRP8, KLF4, NCOR1, NCOR2
9positive regulation of cell proliferationGO:00828449.7PDCD10, REG1A, CNTF, CNTFR, KIT, VSX2
10negative regulation of transcription, DNA-dependentGO:04589247.9ZNF148, ZNF746, ZNF423, ZNF238, KLF4, RFX3
11nerve growth factor receptor signaling pathwayGO:04801146.4PIK3CB, PIK3CA, PIK3R2, PIK3R1, SH3GL2, NDN
12protein phosphorylationGO:00646846.3PIK3CD, PINK1, PICK1, PIM1, RET, SGK1
13response to drugGO:04249346.1LRP2, NCF2, PDE3A, PDE4A, REN, SFRP1
14negative regulation of cell proliferationGO:00828545.4KLF4, NDN, NCK2, REST, KIFAP3, KISS1R
15negative regulation of apoptotic processGO:04306644.6PIK3CG, PIM1, PDCD10, PDE3A, RELA, SFRP1
16G-protein coupled receptor signaling pathwayGO:00718641.6PIK3CB, PIK3CG, KISS1, KISS1R, GCG, VIP
17cell proliferationGO:00828341.4ZNF259, PIM1, WDR12, LRP2, REG1B, KITLG
18cell-cell signalingGO:00726738.8SH2D1A, PCDH1, PCDH8, PCSK5, PCSK1, SEMA3B
19virus-host interactionGO:01904836.2PIK3R1, PDCD6IP, RELA, RCOR1, BTRC, RB1
20anti-apoptosisGO:00691635.2PIK3CA, SH3GLB1, RELA, GCLC, SEMA4D, NAIP
21inflammatory responseGO:00695434.6PIK3CD, PIK3CG, RELA, CNR2, KIT, SELE
22response to hypoxiaGO:00166633.6SERPINA1, VEGFA, BNIP3, BMP2, RAF1, UTS2
23positive regulation of apoptotic processGO:04306532.6LRP6, NCOA1, REST, CNR1, SFRP1, SFRP4
24angiogenesisGO:00152531.6PIK3CA, PIK3CG, NCL, PDCD10, PDE3B, SETD2
25homophilic cell adhesionGO:00715630.8PIK3CB, RET, PCDH1, PCDH10, PCDH18, PCDH8
26brain developmentGO:00742030.7KLHL17, RELN, CNTN4, CNTNAP2, PCDH18, SEPP1
27epidermal growth factor receptor signaling pathwayGO:00717330.7PIK3CA, PIK3R1, PIK3C2A, SH3GL2, NCK2, PDE1A
28neuron migrationGO:00176430.3NDN, RELN, CNTN2, KIAA0319, KIRREL3, PCNT
29protein autophosphorylationGO:04677730.1PIM1, KIT, LMTK2, MYLK2, PAK1, PAK2
30negative regulation of neuron apoptotic processGO:04352429.9CNTF, CNTFR, GCLM, SET, NAIP, BRAF
31fibroblast growth factor receptor signaling pathwayGO:00854328.0PIK3CA, PIK3R1, PDE1A, PDE1B, PDE1C, KIF16B
32neuron differentiationGO:03018227.9PCSK9, BTG4, NAPA, BRSK1, BRSK2, LMX1B
33insulin receptor signaling pathwayGO:00828627.3PIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3C2A
34potassium ion transportGO:00681327.0KCNA10, KCNA3, KCNA5, KCNAB1, KCNC1, KCNC4
35elevation of cytosolic calcium ion concentrationGO:00720425.7GCK, LPAR1, LPAR3, UTS2, UTS2R, BDKRB2
36induction of apoptosis by extracellular signalsGO:00862425.1NCSTN, PDCD6, VDR, VAV2, RASGRF1, RASGRF2
37agingGO:00756825.1LRP2, NCF2, CNR1, SERPINF1, VDR, BAK1
38response to estradiol stimulusGO:03235522.9NCOA1, SFRP4, SERPINA1, BRCA2, VDR, BMP4
39positive regulation of cell migrationGO:03033522.8RET, SEMA4D, VEGFA, MYLK, MYO1F, BMP2
40positive regulation of neuron differentiationGO:04566622.3NCOA1, VWC2, VWC2L, NBL1, BNIP2, BMP2
41positive regulation of neuron projection developmentGO:01097620.3RELN, RET, CNR1, SERPINE2, LIF, BCL11A
42transmembrane transportGO:055085INFGCK, RANBP2, RAE1, RAB11A, CFTR, AVP
43blood coagulationGO:007596INFPIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3CG
44nervous system developmentGO:007399INFZNF423, LRCH4, SH2B2, NDEL1, NDN, RFNG
45apoptotic processGO:006915INFPIM1, NCKAP1, NCSTN, PDCD10, PDCD2, PDCD6IP
46transportGO:006810INFNDEL1, CNGA1, CNGA3, CNGB1, CNGB3, MYO5A
47platelet activationGO:030168INFPIK3CB, PIK3CA, PIK3R3, PIK3R2, PIK3R1, PIK3CG
48small molecule metabolic processGO:044281INFPIK3CB, PIK3CD, PI4K2A, PIP5K1B, PIK3CA, PIK3R3
49cell adhesionGO:007155INFLRFN3, NCAM1, NCAN, RELN, CNTN1, CNTN2
50cell deathGO:008219INFPINK1, KIF1A, KIF5A, , SETX, BSCL2

Molecular functions related to neuronitis according to GeneDecks:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:005515INFZNF148, ZNF746, ZNF711, ZNF423, ZNF326, PIK3CB
2G-protein coupled receptor activityGO:004930136.7VIPR2, LPAR1, LPAR3, LPHN1, LPHN2, LPHN3
3olfactory receptor activityGO:004984119.0OR4D2, OR4F15, OR4F6, OR10C1, OR4M1, OR51J1
4sequence-specific DNA binding transcription factor activityGO:00370087.2ZNF148, ZNF238, KLF4, KLF6, RFX3, REL
5calcium ion bindingGO:00550968.9LRP4, LRP1, LRP2, LRP8, NCALD, NCAN
6sequence-specific DNA bindingGO:04356563.5ZNF148, ZNF711, ZNF238, VSX1, VSX2, GCM2
7protein homodimerization activityGO:04280360.6LRP4, LRP6, SH3GLB1, PDCD10, PDCD6, PDE2A
8receptor bindingGO:00510243.9PICK1, LRRC4B, LRP6, NCK1, REN, CNTFR
9protein heterodimerization activityGO:04698241.2GCA, GCLM, NAE1, BRAF, VEGFA, VEGFB
10protein kinase bindingGO:01990138.5RELA, KIF13B, RB1CC1, VIM, BRSK1, BRSK2
11protein serine/threonine kinase activityGO:00467437.9PIK3CA, PINK1, PIK3CG, PIM1, SGK1, SGK2
12transcription factor bindingGO:00813433.7PIM1, RELA, REST, RB1, RBFOX2, RBL1
13phospholipid bindingGO:00554333.6SH2B1, SH2B2, SGIP1, CNKSR2, KIF1A, KIF1B
14enzyme bindingGO:01989933.1PICK1, NCOA1, CNTNAP2, GCHFR, BTG1, BRCA1
15calmodulin bindingGO:00551631.5PDE1A, PDE1B, PDE1C, CNN1, CNN2, CNN3
16signal transducer activityGO:00487131.4SH2B1, SH2B2, NDFIP1, NCOA1, VAPA, RASGRP3
17receptor activityGO:00487230.6LRP1, RET, CNTNAP1, BTN1A1, SEMA3C, SEMA3D
18growth factor activityGO:00808330.0REG1A, CNTF, KITLG, VGF, VEGFA, VEGFB
19transcription regulatory region DNA bindingGO:04421228.4ZNF513, ZNF746, KLF4, RFX3, NCOR1, RELA
20protein C-terminus bindingGO:00802227.8PICK1, NCF2, NCL, RBFOX1, VIM, RAB3A
21ubiquitin protein ligase bindingGO:03162527.7ZNF746, PINK1, RELA, RB1, RBX1, NAE1
22protein domain specific bindingGO:01990426.6PICK1, SFN, VCP, BMP2, RAB27B, RARA
23PDZ domain bindingGO:03016521.2LPAR1, LPHN2, LNX1, LIN7A, LIN7C, CLCN3
24voltage-gated potassium channel activityGO:00524920.8KCNA10, KCNA7, KCNAB1, KCNB1, KCNC1, KCNC4
25RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityGO:00370519.4RFX1, RFX3, RELA, MYF5, MYOD1, USF2
26drug bindingGO:00814418.7PDE2A, PDE3B, PDE4C, CNR1, SFRP1, CHRM2
27RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positiveGO:00107718.6KLF4, BTG2, RBPJ, BCL11B, BARHL1, BARHL2
28calcium channel activityGO:00526217.9PDE2A, PANX1, P2RX1, GRIN1, GRIN2A, GRIN2B
29chromatin bindingGO:003682INFNCOA1, RELA, REST, RBMX, LMO2, RAN
30protein kinase activityGO:004672INFPIK3CG, PIK3C3, BRAF, RAF1, LIMK1, PACSIN1
31identical protein bindingGO:042802INFPICK1, SH3GL2, SH3GL3, SH3GLB1, RELA, CNTN2
32ATP bindingGO:005524INFPIK3CB, PIK3CD, PI4K2A, PIP5K1B, PIK3CA, PINK1

Sources for Neuronitis

2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS