Aliases & Classifications for Neuronitis

MalaCards integrated aliases for Neuronitis:

Name: Neuronitis 12 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:8117
NCIt 47 C34847
UMLS 69 C0027881

Summaries for Neuronitis

Disease Ontology : 12 A central nervous system disease that is characterized by neuron inflammation.

MalaCards based summary : Neuronitis is related to malignant hypertension and lymphoma. An important gene associated with Neuronitis is MB (Myoglobin), and among its related pathways/superpathways are TRAF Pathway and Apoptosis and Autophagy. The drugs Methylprednisolone and Prednisolone have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and spinal cord.

Related Diseases for Neuronitis

Diseases related to Neuronitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1103)
id Related Disease Score Top Affiliating Genes
1 malignant hypertension 28.9 CD40LG MB
2 lymphoma 28.6 CD40LG TNFRSF10A
3 ceroid lipofuscinosis, neuronal, 3 12.3
4 motor neuron disease 12.2
5 ceroid lipofuscinosis, neuronal, 10 12.2
6 ceroid lipofuscinosis, neuronal, 1 12.2
7 neuronal ceroid lipofuscinosis 12.2
8 ceroid lipofuscinosis, neuronal, 2 12.2
9 ceroid lipofuscinosis, neuronal, 5 12.2
10 ceroid lipofuscinosis, neuronal, 6 12.2
11 ceroid lipofuscinosis, neuronal, 4, parry type 12.2
12 ceroid lipofuscinosis, neuronal, 7 12.2
13 ceroid lipofuscinosis, neuronal, 8, northern epilepsy variant 12.2
14 ceroid lipofuscinosis, neuronal, 13, kufs type 12.1
15 adult neuronal ceroid lipofuscinosis 12.1
16 ceroid lipofuscinosis, neuronal, 8 12.1
17 ceroid lipofuscinosis, neuronal, 11 12.1
18 neuronal intranuclear inclusion disease 12.1
19 vestibular neuronitis 12.1
20 madras motor neuron disease 12.1
21 neuronal migration disorders 12.1
22 ceroid lipofuscinosis, neuronal, kufs type, adult onset 12.1
23 ceroid lipofuscinosis, neuronal, 9 12.1
24 neuronal intestinal dysplasia 12.0
25 neuronal ceroid lipofuscinosis 4a 12.0
26 intestinal pseudoobstruction, neuronal 12.0
27 neuronal ceroid-lipofuscinoses 12.0
28 survival motor neuron spinal muscular atrophy 11.8
29 nodular neuronal heterotopia 11.7
30 amyotrophic lateral sclerosis 1 11.7
31 focal or multifocal malformations in neuronal migration 11.6
32 neuronal interstitial dysplasia 11.6
33 amyotrophic lateral sclerosis 4, juvenile 11.6
34 pick disease 11.6
35 lateral sclerosis 11.5
36 mitochondrial dna depletion syndrome 4a 11.3
37 frontotemporal dementia and/or amyotrophic lateral sclerosis 1 11.3
38 spinal muscular atrophy, distal, autosomal recessive, 4 11.3
39 alzheimer disease 11.3
40 spinal muscular atrophy 11.3
41 mental retardation, autosomal dominant 13 11.2
42 progressive muscular atrophy 11.2
43 epilepsy, progressive myoclonic 3, with or without intracellular inclusions 11.2
44 neuropathy, distal hereditary motor, type viib 11.2
45 spastic paraplegia 39, autosomal recessive 11.2
46 spinal muscular atrophy, jokela type 11.2
47 juvenile amyotrophic lateral sclerosis 11.1
48 cerebellar degeneration 11.1
49 primary lateral sclerosis, juvenile 11.1
50 niemann-pick disease 11.1

Graphical network of the top 20 diseases related to Neuronitis:



Diseases related to Neuronitis

Symptoms & Phenotypes for Neuronitis

Drugs & Therapeutics for Neuronitis

Drugs for Neuronitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 39)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3 83-43-2 6741
2
Prednisolone Approved, Vet_approved Phase 4,Phase 3 50-24-8 5755
3
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
4 Antiemetics Phase 4,Phase 3
5 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
6 Antineoplastic Agents, Hormonal Phase 4,Phase 3,Phase 2
7 Autonomic Agents Phase 4,Phase 3
8 Gastrointestinal Agents Phase 4,Phase 3
9 glucocorticoids Phase 4,Phase 3,Phase 2
10 Hormone Antagonists Phase 4,Phase 3,Phase 2
11 Hormones Phase 4,Phase 3,Phase 2
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
13 Methylprednisolone acetate Phase 4,Phase 3
14 Methylprednisolone Hemisuccinate Phase 4,Phase 3
15 Neuroprotective Agents Phase 4,Phase 3
16 Peripheral Nervous System Agents Phase 4,Phase 3
17 Prednisolone acetate Phase 4,Phase 3
18 Prednisolone hemisuccinate Phase 4,Phase 3
19 Prednisolone phosphate Phase 4,Phase 3
20 Protective Agents Phase 4,Phase 3
21 Anti-Asthmatic Agents Phase 4,Phase 3
22 Betamethasone benzoate Phase 4
23 Betamethasone sodium phosphate Phase 4
24 Betamethasone Valerate Phase 4 2152-44-5
25 Betamethasone-17,21-dipropionate Phase 4
26 Respiratory System Agents Phase 4,Phase 3
27
Cilostazol Approved Phase 3 73963-72-1 2754
28 Bronchodilator Agents Phase 3
29 Fibrinolytic Agents Phase 3
30 Phosphodiesterase 3 Inhibitors Phase 3
31 Phosphodiesterase Inhibitors Phase 3
32 Platelet Aggregation Inhibitors Phase 3
33 Vasodilator Agents Phase 3
34 Ginkgo Nutraceutical Phase 3
35
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
36
Dexamethasone Approved, Investigational, Vet_approved Early Phase 1 50-02-2 5743
37
Menthol Approved Early Phase 1 2216-51-5 16666
38 BB 1101 Early Phase 1
39 Dexamethasone acetate Early Phase 1 1177-87-3

Interventional clinical trials:

(show all 13)

id Name Status NCT ID Phase Drugs
1 Acute Unilateral Vestibulopathy and Corticosteroid Treatment Recruiting NCT02912182 Phase 4 Betamethasone;Placebo;Prednisolone
2 The Efficacy of Steroid Therapy in Vestibular Neuritis Unknown status NCT02098330 Phase 3 Ginkgo biloba & Methylprednisolone;Ginkgo biloba
3 Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy Terminated NCT01895400 Phase 3 Renexin (cilostazol 100mg + gingko biloba extract 80 mg);Placebo
4 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
5 Complementary/Alternative Medicine for Abnormality in the Vestibular (Balance) System Completed NCT00032383 Phase 1, Phase 2
6 Characterisation of Cortical Vestibular Evoked Potentials (C-VEPs) Unknown status NCT02463695
7 The Role of Corticosteroids and Vestibular Exercises in Recovery of Vestibular Neuritis Unknown status NCT01231009 Early Phase 1 Corticosteroids
8 Vestibular System in Migrainous Vertigo Patients Unknown status NCT00901953
9 Recovery of Visual Acuity in People With Vestibular Deficits Completed NCT00411216
10 Home-based Computer Gaming in Vestibular Rehabilitation Completed NCT01943955
11 Clinical Evaluation of a Novel Balance, Vestibular and Oculomotor Assessment Tool Completed NCT02171312
12 Assessment and Treatment of Patients With Long-term Dizziness in Primary Care Recruiting NCT02655575
13 Vestibulopathy With Vestibulo Ocular Reflex (VOR) Gain Deficit Not yet recruiting NCT03271775

Search NIH Clinical Center for Neuronitis

Genetic Tests for Neuronitis

Anatomical Context for Neuronitis

MalaCards organs/tissues related to Neuronitis:

39
Brain, Cortex, Spinal Cord, Lung, Dorsal Root Ganglion, Hypothalamus, Bone

Publications for Neuronitis

Articles related to Neuronitis:

(show top 50) (show all 17061)
id Title Authors Year
1
Gut inflammation and dysbiosis in human motor neuron disease. ( 28947596 )
2017
2
Neuronal death signaling pathways triggered by mutant LRRK2. ( 28202665 )
2017
3
Germline and somatic mutations in cortical malformations: Molecular defects in Argentinean patients with neuronal migration disorders. ( 28953922 )
2017
4
Dataset in support of the generation of Niemann-Pick disease Type C1 patient-specific iPS cell lines carrying the novel NPC1 mutation c.1180T>C or the prevalent c.3182T>C mutation - Analysis of pluripotency and neuronal differentiation. ( 28413817 )
2017
5
Dementia with Lewy bodies: cerebrospinal fluid suppresses neuronal network activity. ( 28953602 )
2017
6
Efficient induction of dopaminergic neuron differentiation from induced pluripotent stem cells reveals impaired mitophagy in PARK2 neurons. ( 28057485 )
2017
7
Selective imaging of internalized proteopathic I+-synuclein seeds in primary neurons reveals mechanistic insight into transmission of synucleinopathies. ( 28611062 )
2017
8
P2X receptors up-regulate the cell-surface expression of the neuronal glycine transporter GlyT2. ( 28734869 )
2017
9
Serum antibodies targeting neurons of the monoaminergic systems in Guillain-BarrAc syndrome. ( 28017237 )
2017
10
Identification of two classes of somatosensory neurons that display resistance to retrograde infection by rabies virus. ( 28951448 )
2017
11
Epilepsy-causing sequence variations in SIK1 disrupt synaptic activity response gene expression and affect neuronal morphology. ( 27966542 )
2017
12
Proteomic Analysis of Brain and Cerebrospinal Fluid from the Three Major Forms of Neuronal Ceroid Lipofuscinosis Reveals Potential Biomarkers. ( 28792770 )
2017
13
Neuroprotective effects of ischemic preconditioning on hippocampal CA1 pyramidal neurons through maintaining calbindin D28k immunoreactivity following subsequent transient cerebral ischemia. ( 28761424 )
2017
14
Putative Mechanism of Salt-Dependent Neurogenic Hypertension: Cell-Autonomous Activation of Organum Vasculosum Laminae Terminalis Neurons by Hypernatremia. ( 27895191 )
2017
15
Genetic dissection of oligodendroglial and neuronal Plp1 function in a novel mouse model of spastic paraplegia type 2. ( 28836307 )
2017
16
Lycopene inhibits regulator of calcineurin 1-mediated apoptosis by reducing oxidative stress and down-regulating Nucling in neuronal cells. ( 27928873 )
2017
17
High serum levels of BMP-2 correlate with BMP-4 and BMP-5 levels and induce reduced neuronal phenotype in patients with relapsing-remitting multiple sclerosis. ( 28778435 )
2017
18
Motor neuron disease mortality and lifetime petrol lead exposure: Evidence from national age-specific and state-level age-standardized death rates in Australia. ( 27992849 )
2017
19
Human microvascular endothelial cell promotes the development of dorsal root ganglion neurons via BDNF pathway in a co-culture system. ( 28394221 )
2017
20
The death wish and motor neuron disease! The chameleons and new research optimism. ( 28084230 )
2017
21
Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy. ( 28077719 )
2017
22
Long-term follow-up of two siblings with adult-onset neuronal ceroid lipofuscinosis, Kufs type A. ( 28587997 )
2017
23
Auditory Neuropathy after Damage to Cochlear Spiral Ganglion Neurons in Mice Resulting from Conditional Expression of Diphtheria Toxin Receptors. ( 28743950 )
2017
24
Synergistic Toxicity of Polyglutamine-Expanded TATA-Binding Protein in Glia and Neuronal Cells: Therapeutic Implications for Spinocerebellar Ataxia 17. ( 28821675 )
2017
25
Combined l-citrulline and glutathione administration prevents neuronal cell death following transient brain ischemia. ( 28315310 )
2017
26
Transient Global Cerebral Ischemia Induces RNF213, a Moyamoya Disease Susceptibility Gene, in Vulnerable Neurons of the Rat Hippocampus CA1 Subregion and Ischemic Cortex. ( 28734662 )
2017
27
MicroRNA-433 Inhibits the Proliferation and Migration of HUVECs and Neurons by Targeting Hypoxia-Inducible Factor 1 Alpha. ( 27815672 )
2017
28
Primary fibroblasts from CSPI+ mutation carriers recapitulate hallmarks of the adult onset neuronal ceroid lipofuscinosis. ( 28740222 )
2017
29
Maternal Hypermethioninemia Affects Neurons Number, Neurotrophins Levels, Energy Metabolism, and Na(+),K(+)-ATPase Expression/Content in Brain of Rat Offspring. ( 28084592 )
2017
30
Amyloid-I^ oligomers transiently inhibit AMP-activated kinase and cause metabolic defects in hippocampal neurons. ( 28302722 )
2017
31
Increased expression of ApoA1 after neuronal injury may be beneficial for healing. ( 27734225 )
2017
32
BGP-15 prevents the death of neurons in a mouse model of familial dysautonomia. ( 28439028 )
2017
33
Activation of KCNQ channels suppresses spontaneous activity in DRG neurons and reduces chronic pain after spinal cord injury. ( 28073317 )
2017
34
The influence of TSA and VPA on the in vitro differentiation of bone marrow mesenchymal stem cells into neuronal lineage cells: Gene expression studies. ( 28397704 )
2017
35
Parkinsonism without dopamine neuron degeneration in aged l-dopa-responsive dystonia knockin mice. ( 28949038 )
2017
36
O-GlcNAc Transferase Is Essential for Sensory Neuron Survival and Maintenance. ( 28115479 )
2017
37
Reduced TDP-43 Expression Improves Neuronal Activities in a Drosophila Model of Perry Syndrome. ( 28625517 )
2017
38
Corrigendum to "Genetic epidemiology of motor neuron disease-associated variants in the Scottish population." [Neurobiol. Aging 51 (2017) 178.e11-178.e20]. ( 28606583 )
2017
39
LOTUS overexpression accelerates neuronal plasticity after focal brain ischemia in mice. ( 28880879 )
2017
40
Cerebrospinal fluid neurofilament light concentration in motor neuron disease and frontotemporal dementia predicts survival. ( 28631955 )
2017
41
Neuronal-Glial Interactions Maintain Chronic Neuropathic Pain after Spinal Cord Injury. ( 28951789 )
2017
42
Ginsenoside Rg3 Improves Recovery from Spinal Cord Injury in Rats via Suppression of Neuronal Apoptosis, Pro-Inflammatory Mediators, and Microglial Activation. ( 28085110 )
2017
43
MR Imaging Features of the Cerebellum in Adult-Onset Neuronal Intranuclear Inclusion Disease: 8 Cases. ( 28818825 )
2017
44
Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology. ( 28747389 )
2017
45
Neuronal Roles of the Bicaudal D Family of Motor Adaptors. ( 28215293 )
2017
46
Clinical profile of motor neuron disease patients with lower urinary tract symptoms and neurogenic bladder. ( 28566149 )
2017
47
Neuron navigator-2 and cyclin D2 are new candidate prognostic markers in uterine sarcoma. ( 28643014 )
2017
48
SFRP2 enhanced the adipogenic and neuronal differentiation potentials of stem cells from apical papilla. ( 28244619 )
2017
49
The tubulin deacetylase sirtuin-2 regulates neuronal differentiation through the ERK/CREB signaling pathway. ( 27838300 )
2017
50
Sex and Age Differences in Motion Sickness in Rats: The Correlation with Blood Hormone Responses and Neuronal Activation in the Vestibular and Autonomic Nuclei. ( 28261089 )
2017

Variations for Neuronitis

Expression for Neuronitis

Search GEO for disease gene expression data for Neuronitis.

Pathways for Neuronitis

Pathways related to Neuronitis according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.69 CD40LG TNFRSF10A
2 11.22 CD40LG TNFRSF10A
3
Show member pathways
10.55 CD40LG TNFRSF10A

GO Terms for Neuronitis

Biological processes related to Neuronitis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 8.96 CD40LG TNFRSF10A
2 tumor necrosis factor-mediated signaling pathway GO:0033209 8.62 CD40LG TNFRSF10A

Sources for Neuronitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
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36 IUPHAR
37 KEGG
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40 MedGen
42 MeSH
43 MESH via Orphanet
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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