MCID: NRP037
MIFTS: 44

Neuropathy, Hereditary Sensory and Autonomic, Type V malady

Categories: Genetic diseases, Rare diseases, Neuronal diseases, Gastrointestinal diseases

Aliases & Classifications for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section
Sources:
49OMIM, 11diseasecard, 45NIH Rare Diseases, 22GeneTests, 23Genetics Home Reference, 67UniProtKB/Swiss-Prot, 51Orphanet, 24GTR, 65UMLS, 36MeSH, 47Novoseek, 37MESH via Orphanet, 66UMLS via Orphanet, 28ICD10 via Orphanet, 34MedGen, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Neuropathy, Hereditary Sensory and Autonomic, Type V:

Name: Neuropathy, Hereditary Sensory and Autonomic, Type V 49 11 45
Hsan5 45 22 23 51 67
Indifference to Pain, Congenital, Autosomal Recessive 23 67 24 65
Hsan V 45 22 23 67
Hereditary Sensory and Autonomic Neuropathy Type V 45 22 23
Channelopathy-Associated Insensitivity to Pain 22 23 67
Congenital Insensitivity to Pain 22 23 67
Congenital Sensory Neuropathy with Selective Loss of Small Myelinated Fibers 23 24
Congenital Insensitivity to Pain and Thermal Analgesia 45 51
Hereditary Sensory and Autonomic Neuropathy Type 5 45 51
Insensitivity to Pain, Congenital 49 45
Pain Insensitivity, Congenital 23 36
Asymbolia for Pain 23 67
Hsan Type V 23 47
 
Cip 23 67
Congenital Indifference to Pain, Autosomal Recessive 22
Hereditary Sensory and Autonomic Neuropathy, Type 5 23
Neuropathy, Hereditary Sensory and Autonomic, 5 67
Insensitivity to Pain, Channelopathy-Associated 11
Hereditary Sensory Autonomic Neuropathy, Type 5 65
Congenital Analgesia Autosomal Recessive 67
Hereditary Sensory Neuropathy Type V 67
Congenital Indifference to Pain 23
Congenital Pain Indifference 23
Hsan2d, Autosomal Recessive 49
Congenital Analgesia 23
Hsn V 67

Characteristics:

Orphanet epidemiological data:

51
hsan5:
Inheritance: Autosomal recessive; Age of onset: Infancy,Neonatal

HPO:

61
insensitivity to pain, congenital:
Onset and clinical course: infantile onset
Inheritance: autosomal recessive inheritance
neuropathy, hereditary sensory and autonomic, type v:
Inheritance: autosomal recessive inheritance
Onset and clinical course: infantile onset


Classifications:



External Ids:

Orphanet51 64752
MESH via Orphanet37 D000699
UMLS via Orphanet66 C0002768, C0020075
ICD10 via Orphanet28 G60.8
UMLS65 C0020075, C1855739

Summaries for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section
OMIM:49 Congenital indifference to pain is a rare autosomal recessive disorder characterized by the complete absence of pain... (243000) more...

MalaCards based summary: Neuropathy, Hereditary Sensory and Autonomic, Type V, also known as hsan5, is related to insensitivity to pain, congenital, with anhidrosis and congenital insensitivity to pain with severe intellectual disability, and has symptoms including intellectual disability, mild, episodic fever and pain insensitivity. An important gene associated with Neuropathy, Hereditary Sensory and Autonomic, Type V is NGF (Nerve Growth Factor), and among its related pathways are NGF Pathway and Apoptosis Modulation and Signaling. Affiliated tissues include bone, tongue and heart, and related mouse phenotypes are normal and integument.

Genetics Home Reference:23 Congenital insensitivity to pain is a condition that inhibits the ability to perceive physical pain. From birth, affected individuals never feel pain in any part of their body when injured. People with this condition can feel the difference between sharp and dull and hot and cold, but cannot sense, for example, that a hot beverage is burning their tongue. This lack of pain awareness often leads to an accumulation of wounds, bruises, broken bones, and other health issues that may go undetected. Young children with congenital insensitivity to pain may have mouth or finger wounds due to repeated self-biting and may also experience multiple burn-related injuries. These repeated injuries often lead to a reduced life expectancy in people with congenital insensitivity to pain. Many people with congenital insensitivity to pain also have a complete loss of the sense of smell (anosmia).

NIH Rare Diseases:45 Hereditary sensory and autonomic neuropathy type v (hsan5) is a condition that affects the sensory nerve cells. these cells, which are also called sensory neurons, transmit information about sensations such as pain, temperature, and touch. signs and symptoms of the condition generally develop at birth or during early infancy and may include a loss of pain and temperature sensation. because of the inability to feel deep pain, affected people suffer repeated severe injuries such as bone fractures and joint injuries that go unnoticed. hsan5 is caused by changes (mutations) in the ngf gene and is inherited in an autosomal recessive manner. medical management is based on the signs and symptoms present in each person and is oriented to control hyperthermia (elevated body temperature) and prevent injury. last updated: 10/27/2015

UniProtKB/Swiss-Prot:67 Indifference to pain, congenital, autosomal recessive: A disorder characterized by congenital inability to perceive any form of pain, in any part of the body. All other sensory modalities are preserved and the peripheral and central nervous systems are apparently intact. Patients perceive the sensations of touch, warm and cold temperature, proprioception, tickle and pressure, but not painful stimuli. There is no evidence of a motor or sensory neuropathy, either axonal or demyelinating. Neuropathy, hereditary sensory and autonomic, 5: A form of hereditary sensory and autonomic neuropathy, a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable.

Description from OMIM:49 608654

Related Diseases for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section

Diseases in the Neuropathy, Hereditary Sensory and Autonomic, Type V family:

Neuropathy, Hereditary Sensory and Autonomic, Type Vii Neuropathy, Hereditary Sensory and Autonomic, Type Iib
Neuropathy, Hereditary Sensory and Autonomic, Type Vi Neuropathy, Hereditary Sensory and Autonomic, Type Ia
Neuropathy, Hereditary Sensory and Autonomic, Type Viii Neuropathy, Hereditary Sensory and Autonomic, Type Ii
Neuropathy, Hereditary Sensory and Autonomic, Type Ic Hereditary Sensory and Autonomic Neuropathy Type Iic

Diseases related to Neuropathy, Hereditary Sensory and Autonomic, Type V via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
idRelated DiseaseScoreTop Affiliating Genes
1insensitivity to pain, congenital, with anhidrosis12.7
2congenital insensitivity to pain with severe intellectual disability12.7
3congenital insensitivity to pain with hyperhidrosis12.6
4neuropathy, hereditary sensory and autonomic, type vii11.6
5hereditary sensory neuropathy11.6
6critical illness polyneuropathy10.7
7plague10.4
8neuropathy, hereditary sensory and autonomic, type ia10.3
9systemic lupus erythematosus10.3
10pick disease10.3
11pancreatic cancer10.3
12niemann-pick disease10.3
13dracunculiasis10.3
14pancreatitis10.3
15lupus erythematosus10.3
16retinitis10.3
17hepatitis10.2
18rheumatoid arthritis10.1
19renal cell carcinoma10.1
20celiac disease10.1
21bloom syndrome10.1
22arthritis10.1
23lymphoma10.1
24osteogenesis imperfecta10.1
25hepatitis c10.1
26aortic aneurysm10.1
27infertility10.1
28pneumonia10.1
29abdominal aortic aneurysm10.1
30peritonitis10.1
31oral cavity carcinoma in situ10.0NGF, NTRK1
32thrombotic thrombocytopenic purpura, familial9.9NGF, NTRK1
33pertussis9.9NGF, NTRK1
34ischemic neuropathy9.9NGF, NTRK1
35kidney cancer9.9NGF, NTRK1
36suppurative otitis media9.8NGF, NTRK1
37pheochromocytoma9.8NGF, NTRK1
38spastic ataxia 19.6NGF, NTRK1
39diamond-blackfan anemia9.6NGF, SCN9A
40neuropathy, hereditary sensory and autonomic, type v9.5NGF, NTRK1, SCN9A
41jmp syndrome9.4NGF, NTRK1, SCN9A

Graphical network of the top 20 diseases related to Neuropathy, Hereditary Sensory and Autonomic, Type V:



Diseases related to neuropathy, hereditary sensory and autonomic, type v

Symptoms for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section

Symptoms by clinical synopsis from OMIM:

243000

Clinical features from OMIM:

608654,243000

HPO human phenotypes related to Neuropathy, Hereditary Sensory and Autonomic, Type V:

(show all 11)
id Description Frequency HPO Source Accession
1 intellectual disability, mild rare (5%) HP:0001256
2 episodic fever rare (5%) HP:0001954
3 pain insensitivity HP:0007021
4 hyposmia HP:0004409
5 painless fractures due to injury HP:0002661
6 hyporeflexia HP:0001265
7 anosmia HP:0000458
8 self-mutilation HP:0000742
9 anhidrosis HP:0000970
10 acral ulceration and osteomyelitis leading to autoamputation of digits HP:0001226
11 acral ulceration and osteomyelitis leading to autoamputation of the digits (feet) HP:0001862

Drugs & Therapeutics for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section

Drugs for Neuropathy, Hereditary Sensory and Autonomic, Type V (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 78)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
RopivacaineapprovedPhase 465084057-95-471273, 175805
Synonyms:
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide
(2S)-N-(2,6-dimethylphenyl)-1-propylpiperidine-2-carboxamide hydrochloride
(S)-(−)-1-propyl-2',6'-pipecoloxylidide
(S)-ropivacaine
84057-95-4
98717-15-8
AC1L41QM
AC1L41QN
BIDD:GT0203
C07532
C17H26N2O.HCl
CHEBI:8890
CHEMBL1077896
CID175804
CID175805
CPD000469137
D08490
I14-176
L-N-n-propylpipecolic acid-2,6-xylidide
LS-113954
 
MLS001401363
MolPort-003-983-292
NCGC00164597-01
Naropin
Naropin (TN)
ROPIVACAINE HCl
Ropivacaina
Ropivacaina [INN-Spanish]
Ropivacaina [Spanish]
Ropivacaine
Ropivacaine Hydrochloride
Ropivacaine [INN]
Ropivacaine hydrochloride
Ropivacaine monohydrochloride
Ropivacainum
Ropivacainum [INN-Latin]
S-Ropivacaine
SAM001246524
SMR000469137
ST51051452
ropivacaine monohydrochloride,
ropivacaine monohydrochloride, (S)-isomer
2
KetorolacapprovedPhase 427866635-83-43826
Synonyms:
(+-)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
(+-)-Ketorolac
(+-)-isomer
(.+/-.)-2,3-Dihydro-5-benzoyl-1H-pyrrolizine-1-carboxylic acid
1H-Pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro
5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
5-Benzoyl-1,2-dihydro-3H-pyrrolo(1,2a)pyrrole-1-carboxylic acid
5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
66635-83-4
74103-06-3
AB00053682
AC-545
AC1L1GSW
Acular
Acuvail
BRD-A40639672-234-05-7
C07062
CHEBI:105080
CHEMBL469
CID3826
D020910
D08104
DB00465
 
I14-2832
Ketoralac
Ketorolac
Ketorolac (INN)
Ketorolac Tromethamine
Ketorolac [INN:BAN]
Ketorolaco
Ketorolaco [Spanish]
Ketorolacum
Ketorolacum [Latin]
Kétorolac
LS-139094
Macril
MolPort-005-933-093
NCGC00185990-01
RS 37619
RS-37619
SBB067312
STL018674
Sprix
Toradol (TN)
UNII-YZI5105V0L
ketorolac
rac-Ketorolac
3
Morphineapproved, investigationalPhase 4, Phase 3, Phase 285557-27-25288826
Synonyms:
(-)(5.alpha.,6.alpha.)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(-)-Heroin hydrochloride
(-)-Morphine
(-)Morphine sulfate
(5R,6S,9R,13S,14R)-4,5-Epoxy-N-methyl-7-morphinen-3,6-diol
(5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5alpha,6alpha)-17-methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(5alpha,6alpha)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
(7R,7AS,12BS)-3-METHYL-2,3,4,4A,7,7A-HEXAHYDRO-1H-4,12-METHANO[1]BENZOFURO[3,2-E]ISOQUINOLINE-7,9-DIOL
(7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol
(−)-morphine
17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol
4,5alpha-Epoxy-17-methyl-7-morphinen-3,6alpha-diol
4-methyl-(13R,14S)-12-oxa-4-azapentacyclo[9.6.1.01,13.05,17.07,18]octadeca-7(18),8,10,15-tetraene-10,14-diol
47106-99-0
57-27-2
6211-15-0 (sulfate (2:1) (salt) pentahydrate)
64-31-3
64-31-3 (sulfate (2:1) (salt) anhydrous)
7,8-Didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol
7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
8053-16-5
85201-37-2
Apokyn
Astramorph PF
Avinza
BIDD:GT0147
C01516
CCRIS 5762
CHEBI:17303
CHEMBL70
CID5288826
Cube juice
D-(-)-Morphine
DB00295
DEA No. 9300
DepoDur
Depodur
Diacetylmorphine hydrochloride
Diamorphine hydrochloride
Dolcontin
Dreamer
Dulcontin
Duramorph
Duramorph PF
Duromorph
EINECS 200-320-2
Epimorph
HSDB 2134
Hard stuff
Heroin hydrochloride
Heroine hydrochloride
Hocus
Infumorph
 
Kadian
LS-91748
M-Eslon
M.O.S
MOI
MORPHINE SULFATE
MORPHINE, (5A,6A)-7,8-DIDEHYDRO-4,5-EPOXY-17-METHYLMORPHINIAN-3,6-DIOL, MORPHIUM, MORPHIA, DOLCONTIN, DUROMORPH, MORPHINA, NEPENTHE
MS Contin
MS/L
MS/S
MSIR
Meconium
MolPort-003-849-273
Morfina
Morfina [Italian]
Morphia
Morphin
Morphin [German]
Morphina
Morphina [Italian]
Morphine
Morphine Extra-Forte
Morphine Forte
Morphine H.P
Morphine Sulfate
Morphine [BAN]
Morphinism
Morphinum
Morphitec
Morphium
Morpho
Moscontin
Ms Contin
Ms Emma
NSC11441
Nepenthe
O,O'-Diacetylmorphine hydrochloride
OMS Concentrate
Oramorph SR
Ospalivina
RMS
RMS Uniserts
Rescudose
Roxanol
Roxanol 100
Roxanol UD
SDZ 202-250
SDZ202-250
Statex
Statex Drops
Statex SR
UNII-76I7G6D29C
Unkie
l-Morphine
morphine
nchembio.317-comp1
nchembio.64-comp1
4
Bupivacaineapproved, investigationalPhase 4, Phase 3, Phase 29642180-92-92474
Synonyms:
( inverted exclamation markA)-bupivacaine
(+-)-Bupivacaine
(1)-1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
(RS)-bupivacaine
1-Butyl-2',6'-pipecoloxylidide
1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide
15233-43-9
2180-92-9
38396-39-3
AB00053674
AC-2096
AC1L1DRE
AC1Q5LX4
AH 250
AKOS001637202
AR-1A0242
Anekain
BPBio1_000298
BRD-A01636364-003-05-2
BSPBio_000270
BSPBio_002607
Bio-0886
Bloqueina
Bucaine
Bucaine (TN)
Bupivacaina
Bupivacaina [INN-Spanish]
Bupivacaine
Bupivacaine (INN)
Bupivacaine Carbonate
Bupivacaine HCL
Bupivacaine HCL KIT
Bupivacaine Hydrochloride
Bupivacaine Monohydrochloride, Monohydrate
Bupivacaine [INN:BAN]
Bupivacainum
Bupivacainum [INN-Latin]
Bupivan
C07529
C18H28N2O
CBupivacaine
CHEBI:3215
CHEMBL1098
CID2474
Carbostesin
D07552
DB00297
DL-Bupivacaine
DUR-843
DepoBupivacaine
 
DivK1c_000758
EINECS 218-553-3
EINECS 253-911-2
Exparel
HMS2090F12
IDI1_000758
KBio1_000758
KBio2_002004
KBio2_004572
KBio2_007140
KBio3_001827
KBioGR_001516
KBioSS_002004
KST-1A4609
L000695
LAC-43
LS-109841
LS-2222
MLS001361336
Marcaina
Marcaine
Marcaine HCL
Marcaine Spinal
MolPort-004-955-820
NCGC00178579-01
NCGC00178579-02
NINDS_000758
NSC119660
Prestwick0_000305
Prestwick1_000305
Prestwick2_000305
Prestwick3_000305
Racemic bupivacaine
SMR000058218
SPBio_001558
SPBio_002489
Sensorcaine
Sensorcaine-MPF
Sensorcaine-MPF Spinal
Spectrum2_001589
Spectrum3_000974
Spectrum4_001098
Spectrum5_001483
Spectrum_001524
Transdur-Bupivacaine
UNII-Y8335394RO
Vivacaine
Win 11318
Win 11318 HCl
bupivacaine
cBupivacaine
dl-1-Butyl-2',6'-pipecoloxylidide
5
Fentanylapproved, illicit, investigationalPhase 4, Phase 3, Phase 2705437-38-73345
Synonyms:
1-Phenethyl-4-(N-phenylpropionamido)piperidine
1-Phenethyl-4-N-propionylanilinopiperidine
437-38-7
5-22-08-00049 (Beilstein Handbook Reference)
80832-90-2
990-73-8 (citrate)
AC1L1FQ2
Abstral
Actiq
BIDD:GT0555
BRN 0494484
CHEBI:119915
CHEMBL596
CID3345
D00320
DB00813
Duragesic
Duragesic (TN)
Duragesic-100
Duragesic-12
Duragesic-25
Duragesic-50
Duragesic-75
Durogesic
EINECS 207-113-6
Fentanest
Fentanil
Fentanil [DCIT]
Fentanila
Fentanila [INN-Spanish]
Fentanilo
Fentanyl
Fentanyl (JAN/USAN/INN)
Fentanyl - Novaplus
Fentanyl Citrate
Fentanyl [INN:BAN]
Fentanyl citrate
Fentanyl-100
 
Fentanyl-12
Fentanyl-25
Fentanyl-50
Fentanyl-75
Fentanylum
Fentanylum [INN-Latin]
HSDB 3329
IONSYS
JNS020QD
L001275
LS-124439
Lazanda
Matrifen
MolPort-003-847-369
N-(1-Phenethyl-4-piperidinyl)-N-phenylpropionamide
N-(1-Phenethyl-4-piperidyl)propionanilide
N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
N-(1-Phenethylpiperidin-4-yl)-N-phenylpropionamide
N-(1-phenethylpiperidin-4-yl)-N-phenylpropanamide
N-Phenethyl-4-(N-propionylanilino)piperidine
N-Phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)propanamide
N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide
NCGC00168252-01
Nasalfent
Oprea1_152073
Oprea1_207148
PDSP1_000860
PDSP2_000846
Pentanyl
Phentanyl
Propanamide, N-phenyl-N-(1-(2-phenylethyl)-4-piperidinyl)- (9CI)
R 4263
Rapinyl
Sentonil
Sublimase
Sublimaze
Subsys
UNII-UF599785JZ
fentanyl
6
Hydromorphoneapproved, illicitPhase 4, Phase 3, Phase 2159466-99-95284570
Synonyms:
(-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one
(-)-Hydromorphone
(5alpha)-3-hydroxy-17-methyl-4,5-epoxymorphinan-6-one
18145-12-5
3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one
4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one
4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone
41376-02-7
466-99-9
6-Deoxy-7,8-dihydro-6-oxomorphine
7,8-Dihydromorphinone
C07042
CHEBI:5790
CHEMBL398707
CID5284570
D08047
DB00327
DEA No. 9150
DiMo
Dihydromorfinon
Dihydromorfinon [Czech]
Dihydromorphinone
Dilaudid
Dilaudid Oros
Dilaudid-hp
Dimorphone
EINECS 207-383-5
 
Exalgo
HSDB 3341
Hidromorfona
Hidromorfona [INN-Spanish]
Hydromorfona
Hydromorfona [Spanish]
Hydromorphon
Hydromorphone
Hydromorphone (INN)
Hydromorphone HCL
Hydromorphone Hydrochloride
Hydromorphone [INN:BAN]
Hydromorphonum
Hydromorphonum [INN-Latin]
Idromorfone
Idromorfone [DCIT]
LS-187185
LS-92152
Laudacon
Laudicon
MolPort-004-285-951
Morphinan-6-one, 4,5alpha-epoxy-3-hydroxy-17-methyl- (8CI)
NSC 19046
NSC19046
Novolaudon
UNII-Q812464R06
WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ JQ P1
hydromorphone
7
DexmedetomidineapprovedPhase 4, Phase 3, Phase 2470113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
8
Codeineapproved, illicitPhase 46876-57-35284371
Synonyms:
(-)-Codeine
(5alpha,6alpha)-17-methyl-3-(methyloxy)-7,8-didehydro-4,5-epoxymorphinan-6-ol
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(5α,6α)-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
(6alpha,13alpha)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-ol
3-Methylmorphin
3-methoxy-17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-6alpha-ol
3-methylmorphine
3-o-methylmorphine monohydrate
41444-62-6 (PO4)
7,8-Didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
7,8-Didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methylmorphinan-6-alpha-ol
7,8-didehydro-4,5-ep oxy-3-methoxy-17-methylmorphinan-6-ol
7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-(5alpha, 6alpha)-morphinan 6-ol
7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methylmorphinan-6alpha-ol
76-57-3
AC-11114
AC1Q4DTD
Actacode
Ardinex
C06174
C1653_FLUKA
C1653_SIGMA
C5901_FLUKA
C5901_SIGMA
CCRIS 7555
CHEBI:16714
CHEMBL485
CID5284371
CODEINE (SEE ALSO: CODEINE PHOSPHATE (CAS 52-28-8))
CODEINE BASE
Calcidrine
Codalgin Forte Codate
Codein
Codeine
Codeine (anhydrous)
Codeine Hydrochloride
Codeine Phosphate
Codeine Sulfate
Codeine [BAN]
Codeine anhydrous
 
Codeine solution
Codeinum
Codeína
Codicept
Coducept
Codéine
DB00318
EINECS 200-969-1
HSDB 3043
Isocodeine
L-Codeine
LS-1695
Methylmorphine
MolPort-002-506-913
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5-alpha,6-alpha)- (9CI)
Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5alpha,6alpha)- (9CI)
Morphinan-6alpha-ol, 7,8-didehydro-4,5alpha-epoxy-3-methoxy-17-methyl- (8CI)
Morphine 3-methyl ether
Morphine monomethyl ether
Morphine-3-methyl ester
Morphine-3-methyl ether
N-Methylmorphine
N-methyl norcodine
N-methylnorcodeine
Norcodeine, N-Methyl
Norcodeine, N-methyl
Norcodine, N-Methyl
Norcodine, N-methyl
Novahistine DH
O(3)-Methylmorphine
O(3)-methylmorphine
O3-Methylmorphine
Robitussin AC
STOCK1N-42851
codeina
codeine
codeinum
l-Codeine
metilmorfina
morphine 3-methyl ether
morphine monomethy l ether
morphine monomethyl ether
morphine-3-methyl ether
nchembio.317-comp2
9
GuaifenesinapprovedPhase 451293-14-13516
Synonyms:
3-(2-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-1,2-propanediol
3-(O-Methoxyphenoxy)-propanediol-1,2
3-O-Methoxyphenoxypropane 1:2-diol
7 Select Mucus Relief
Actifed C
Adult Tussin
Adult Tussin chest congestion
Aeronesin
Air Power
Amonidren
Amonidrin
Aresol
Benylin-E
Bidex-400
Bronchol
Broncomar SF
Careone Adult Tussin
Careone Mucus Er
Careone Mucus Relief childrens
Chest Congestion
Chest Congestion Relief
Chest Congestion childrens
Childrens Chest Congestion
Childrens Chest Congestion Relief
Childrens Mucinex Chest Congestion
Childrens Mucinex Mini-Melts Chest Congestion
Childrens Mucus Relief
Childrens Mucus Relief Expectorant Grape
Childrensrelief Expectorant Grape
Cough
Cough Out
Dg Health Mucus Relief Er
Diabetic Siltussin Das-na
Diabetic Tussin Expectorant
Diabetic Tussin Mucus Relief
Equaline Mucus Er
Equaline Tussin chest congestion
Equate Mucus Er
Equate Tussin Adult Chest Congestion
Expectorant
Expectorant 12 Hour
Gadavyt Cough
Geri-tussin Expectorant
Glycerin ether
Glycerin guaiacolate
Glycero-guaiacol ether
Glycerol a-(2-methoxyphenyl) ether
Glycerol a-(O-methoxyphenyl)ether
Glycerol a-guaiacyl ether
Glycerol a-guiacyl ether
Glycerol a-monoguaiacol ether
Glycerol guaiacolate
Glycerol mono(2-methoxyphenyl) ether
Glycerol-a-guajakolether
Glycerol-alpha-guajakolether
Glyceryl guaiacol
Glyceryl guaiacol ether
Glyceryl guaiacolate
Glyceryl guaiacolate ether
Glyceryl guaiacyl ether
Glyceryl guaicolate
Glyceryl guiacolate
Glycerylguaiacol
Good Neighbor Pharmacy Mucus Er
Good Neighbor Pharmacy Mucus Relief
Good Neighbor Pharmacy Tabtussin
Good Neighbor Pharmacy Tussin
Good Sense Mucus Er
Good Sense Mucus Relief
Good Sense Tussin chest congestion
Guaap
Guaiacol glycerol ether
Guaiacol glyceryl ether
Guaiacolglicerinetere
Guaiacuran
Guaiacurane
Guaiacyl glyceryl ether
Guaiamar
Guaianesin
Guaicol glycerine ether
Guaicol glyceryl ether
Guaifenesin
Guaifenesin Extended Release
Guaifenesine
Guaiphenesin
Guaiphenesine
Guaiphesin
Guiatuss
Health Mart Adult Tussin
Health Mart Mucus Er
Healthmart Chest Congestion Relief
Healthy Accents Childrens Mucus Relief
Healthy Accents Mucus Relief
Healthy Accents Tussin
Healthy Accents Tussin Chest Congestion adult
Hustosil
 
Iophen Nr
Kids-eeze Chest Relief
Leader Adult Tussin Chest Congestion
Leader Adult Tussin Mucus Plus Chest Congestion
Leader Chest Congestion Relief G450
Leader Cough Tabs
Leader Mucus Er
Leader Mucus Relief childrens
Leader Tabtussin 400
Licorice Coughing Liquid
Liqufruta
Liquituss Gg
Little Remedies Little Colds Mucus Relief Expectorant Melt Aways
Methoxypropanediol
Methphenoxydiol
Metossipropandiolo
Mucaplex
Mucinex
Mucinex For Kids
Mucinex Maximum Strength
Mucinex for Kids
Mucosa
Mucus Er
Mucus Extended Release
Mucus Releif Expectorant
Mucus Relief
Mucus Relief Chest
Mucus Relief Er
Mucus Relief Expectorant
Mucus Relief Immediate Release
O-Methoxyphenyl glyceryl ether
Organ-i Nr
Organidin NR
Pancold S
Pneumomist
Preferred Plus Chest Congestion Relief
Preferred Plus Mucus Er
Preferred Plus Tabtussin
Premier Value Chest Congestion Relief
Propanosedyl
Q-tussin
Qtussin
Quality Choice Mucus Relief
Reduton
Refenesen
Refenesen Chest Congestion Relief
Respaire-30
Ritussin Expectorant
Robafen Cough Formula
Robitussin
Robitussin Mucus Plus Chest Congestion
Rompe Pecho
Rompe Pecho EX
Rompe Pecho SF
Rugby Mucus Er
Rx Act Tussin Chest Congestion
Scot-tussin Expectorant Sf Cough
Select Brand Coughtab 400
Select Brand Mucus Relief
Select Brand Tab Tussin
Selecthealth Tussin Dm
Shopko Chest Congestion Relief
Shoprite Adult Tussin
Shoprite Mucus Relief
Siltussin Das
Siltussin Sa
Simpex Guaifenesin
Simply Right Mucus Relief
Smart Sense Childrens Mucus Relief
Smart Sense Mucus Er
Smart Sense Tussin adult
Sunmark Mucus Er
Sunmark Tussin
Sunmark Tussin chest congestion
The Medicine Shoppe Chest Congestion Relief
Topcare Mucus Er
Topcare Mucus Relief
Topcare Tussin Chest Congestion
Topcare Tussin mucus plus chest congestion
Tussin
Tussin Adult chest congestion
Tussin Chest
Tussin Chest Congestion Adult Non Drowsy
Tussin Chest Congestion Non Drowsy
Tussin EXPECTORANT
Tussin Non Drowsy
Tussin Original
Tussin adult chest congestion
Tussin adults non drowsy
Tussin expectorant for adults
Tussin mucus plus chest congestion
Ultra Tuss
Wal Tussin adult chest congestion
a-Glyceryl guaiacol ether
a-Glyceryl guaiacolate ether
alpha-Glyceryl guaiacol ether
alpha-Glyceryl guaiacolate ether
guaiphenesin
p-Cresyl acetate
10
EpinephrineapprovedPhase 483451-43-45816
Synonyms:
(-)-(R)-Epinephrine
(-)-3,4-Dihydroxy-a-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
(-)-3,4-Dihydroxy-alpha-[2-(methylamino)ethyl]benzyl alcohol
(-)-3,4-dihydroxy-a-[(methylamino)methyl]-Benzyl alcohol
(-)-3,4-dihydroxy-alpha-[(methylamino)methyl]-Benzyl alcohol
(-)-Adrenalin
(-)-Adrenaline
(-)-Epinephrine
(-)-R-Epinephrine
(R)-(-)-Adnephrine
(R)-(-)-Adrenaline
(R)-(-)-Epinephrine
(R)-(-)-Epirenamine
(R)-(−)-adrenaline
(R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
(R)-4-[1-hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
(R)-Adrenaline
(R)-Epinephrine
(−)-adrenaline
02252_FLUKA
1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
1-Adrenalin
1-Epinephrine
4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol
4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-Benzenediol
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol
4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
51-43-4
51-43-4 (FREE BASE)
51028-73-0
A0173
AC-13188
AC1L1L7B
ADR ADRENALINE
ADROP
AI3-19015
Adnephrine
Adrenaclick
Adrenal
Adrenalin
Adrenalin (TN)
Adrenalin in Oil
Adrenalin-Medihaler
Adrenalina
Adrenalina [DCIT]
Adrenaline
Adrenaline (JP15)
Adrenaline/Epinephrine
Adrenalinum
Adrenamine
Adrenan
Adrenapax
Adrenasol
Adrenatrate
Adrenine
Adrenodis
Adrenohorma
Adrenosan
Adrenutol
Adrin
Adrine
Ana-Guard
Ana-Kit
Antiasthmatique
Asmatane Mist
Asthma meter mist
Asthma-nefrin
Asthmahaler Mist
Asthmanefrin
Astmahalin
Astminhal
Auvi-q
BIDD:GT0119
Balmadren
Bernarenin
Biorenine
Bosmin
Brevirenin
Bronkaid
Bronkaid Mist
Bronkaid Suspension Mist
Bupivacaine Hcl and Epinephrine
C00788
CCRIS 4812
CHEBI:28918
CHEMBL679
CID5816
Chelafrin
Citanest Forte
Corisol
D-Epifrin
D-Epinephrine
D00095
DB00668
Drenamist
Dylephrin
Dyspne-Inhal
E4250_SIGMA
EINECS 200-098-7
EPI E Z PEN JR
EPIPEN E Z PEN
EPIPEN JR
Epi EZ Pen Jr
Epifrin
Epiglaufrin
Epinefrin
Epinefrin [Czech]
Epinefrina
Epinefrina [INN-Spanish]
Epinephran
Epinephrin
Epinephrine
Epinephrine (USP)
Epinephrine (USP/INN)
Epinephrine [USAN:INN:JAN]
Epinephrine bitartrate
Epinephrine chloride
Epinephrine hydrochloride
Epinephrinum
Epinephrinum [INN-Latin]
Epipen
Epipen (TN)
Epipen Auto-Injector
Epipen EZ Pen
Epipen Jr
Epipen Jr.
Epipen Jr. Auto-Injector
Epipen jr
Epirenamine
Epirenan
Epirenin
Epitrate
Eppy
 
Esphygmogenina
Exadrin
Glaucon
Glaucosan
Glauposine
Glycirenan
HSCI1_000215
HSDB 4289
Haemostasin
Haemostatin
Hektalin
Hemisine
Hemostasin
Hemostatin
Hypernephrin
Hyporenin
IOP
Intranefrin
Iontocaine
Isoptoepinal
Kidoline
L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
L-Adrenaline
L-Adrenaline Base
L-Epinehphrine
L-Epinephrine
L-Epirenamine
L-Methylaminoethanolcatechol
L-epinephrine
LS-156
Levo-Methylaminoethanolcatechol
Levoadrenaline
Levoepinephrine
Levorenen
Levorenin
Levorenine
Levoreninum
Lopac-E-4642
Lyodrin
Lyophrin
Medihaler-Epi
Metanephrin
Methylaminoethanolcatechol
Methylarterenol
Micronefrin
Micronephrine
MolPort-002-051-368
Mucidrina
Myosthenine
Mytrate
NCGC00015417-01
NCGC00142615-01
NCGC00142615-03
NCGC00142615-04
NCGC00142615-05
NCGC00142615-06
NCGC00142615-07
NSC 62786
NSC62786
Nephridine
Nieraline
PDSP1_001120
PDSP2_001104
Paranephrin
Primatene
Primatene Mist
Primatene Mist Refill
Prime Asthma Relief
R-(-)-Epinephrine
R-Adrenaline
RCRA waste no. P042
Racemic Epinephrine
Racepinephrine
Rcra waste number P042
Renagladin
Renaglandin
Renaglandulin
Renaleptine
Renalina
Renoform
Renostypricin
Renostypticin
Renostyptin
SMP1_000227
ST069368
SUS-PHRINE SULFITE-FREE
Scurenaline
Septocaine
Simplene
Sindrenina
Soladren
Sphygmogenin
Stryptirenal
Styptirenal
Supracapsulin
Supradin
Supranefran
Supranephrane
Supranephrine
Supranol
Suprarenaline
Suprarenin
Suprel
Surenine
Surrenine
Sus-Phrine
Sus-phrine
Susphrine
Sympathin I
Takamina
Takamine
Tokamina
Tonogen
Twinject
Twinject 0.15
Twinject 0.3
Twinject 0.30
UNII-YKH834O4BH
Vaponefrin
Vasoconstrictine
Vasoconstrictor
Vasodrine
Vasoton
Vasotonin
adrenaline
bmse000316
d-Adrenaline
epinephrine
l-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol
l-Adrenalin
l-Adrenaline
l-Epinephine
l-Epinephrine (synthetic)
l-Epirenamine
l-Methylaminoethanolcatechol
levoepinephrine
nchembio747-comp9
11
IbuprofenapprovedPhase 4, Phase 245615687-27-13672
Synonyms:
(+-)-2-(P-Isobutylphenyl)propionic acid
(+-)-Ibuprofen
(+-)-P-Isobutylhydratropic acid
(+-)-alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid
(4-Isobutylphenyl)-alpha-methylacetic acid
(RS)-ibuprofen
139466-08-3
15687-27-1
2-(4-Isobutylphenyl)propanoic acid
4-Isobutylhydratropic acid
58560-75-1
7 Select Childrens Ibuprofen
7 Select Ibuprofen
AC-11312
AC1L1GGE
AC1Q1P84
AC1Q1P85
ACHES-N-PAIN
ARONIS23835
Act-3
Actiprofen
Adex 200
Adran
Advil
Advil (TN)
Advil Liqui-Gels
Advil Liquigels
Advil Migraine
Ak+C2278tren
Alaxan
Algofen
Am-Fam 400
Amelior
Amersol
Amibufen
Anafen
Anco
Andran
Anflagen
Antagil
Antalfene
Antarene
Antiflam
Apo-Ibuprofen
Aprofen REGULAR STRENGTH
Apsifen
Apsifen-F
Artofen
Artril
Artril 300
BB_SC-1358
BIDD:GT0050
BRN 2049713
Babies R Us Ibuprofen
Babies R Us Infants Ibuprofen
Balkaprofen
Being Well Ibuprofen
Betaprofen
Bloom
Bluton
Brofen
Brufanic
Brufen
Brufen 400
Bruflam
Brufort
Buburone
Bufeno
Bufigen
Bukrefen
Bupron
Buracaps
Burana
Butylenin
C01588
C13H18O2
CCRIS 3223
CHEBI:5855
CHEMBL521
CID3672
CPD000058184
Caldolor
Cap-Profen
Care One Ibuprofen
Care One Ibuprofen Ib
Care One Ibuprofen Junior Strength
Care One Ibuprofen childrens
Care One Ibuprofen infants
Careone Ibuprofen Junior Strength
Carol
Cedaprin
Cesra
Children's Advil
Children's Elixsure
Children's Ibuprofen
Children's Motrin
Childrens Advil
Childrens Ibuprofen
Childrens Ibuprofen 100 Dye Free
Childrens Ibuprofen Oral Suspension
Childrens Motrin
Circle K Ibuprofen
Citalgan
Clear Choice Ibuprofen
Cobo
Codral
Combiflam
Conney Ibuprofen
Counteract IB
Cunil
Cvs Pharmacy Ibuprofen
D00126
D007052
DB01050
DOLO PUREN
Daiprophen
Dalsy
Dansida
Deep Relief
Dentigoa
Dg Health Ibuprofen
Dibufen
Dignoflex
Direct Safety Ibuprofen
Dolex
Dolgin
Dolgirid
Dolgit
Dolibu
Dolmaral
Dolo-Dolgit
Dolo-dolgit
Dolocyl
Dolofen
Dolofen-F
Dolofin
Dolofort
Dologel
Dolomax
Doloren
Dolormin
Doltibil
Dolven
Donjust B
Dorival
Dover Addaprin
Drin
Duafen
Duobrus
Dura-Ibu
Duralbuprofen
Dye Free Ibuprofen
Dysdolen
EU-0100691
Easifon
Ebufac
Emflam
Emflam-200
Emodin
Epobron
Eputex
Equaline Childrens Ibuprofen
Equaline Ibuprofen
Equaline Ibuprofen childrens
Equate Ibuprofen
Equate Ibuprofen childrens
Ergix
Esprenit
Exneural
Family Wellness Childrens Ibuprofen
Faspic
Femadon
Femafen
Femapirin
Femidol
Fenbid
Fenbid Spansule
Fendol
Fenspan
Fibraflex
Film Coated Ibuprofen
Formu Care Ibuprofen
Formu Care Ibuprofen childrens
Fulton Street Market Ibuprofen
Gelufene
Gofen
Good Neighbor Pharmacy Childrens Ibuprofen
Good Neighbor Pharmacy Ibuprofen
Good Neighbor Pharmacy Ibuprofen childrens
Good Sense Childrens Ibuprofen Oral Suspension
Good Sense Ibuprofen
Good Sense Ibuprofen Childrens
Good Sense Ibuprofen childrens
Good Sense Ibuprofen infants
Green Guard Ibupro Relief
Green Guard Ibuprofen Relief
Grefen
Gynofug
HMS1920F15
HMS2089P05
HMS2091N03
HMS502M09
HSDB 3099
Haltran
Harmon Face Values Ibuprofen
Health Mart Childrens Ibuprofen
Health Mart Ibuprofen
Health Mart Ibuprofen Ib
Health Sense Infants Ibuprofen Oral Suspension
Health Sense Provil
Healthy Accents Ibuprofen
Healthy Accents Ibuprofen childrens
Healthy Accents Ibuprofen infants
Help I Have An Aching Body
Henry Schein Ibuprofen
I 4883
I01-7039
I0415
I4883_SIGMA
I7905_SIAL
IB-100
IDI1_000887
IP 82
IP-82
IP82
Ibol
Ibren
Ibu
Ibu-Attritin
Ibu-Slo
Ibu-Tab
Ibu-Tab 200
Ibu-attritin
Ibu-slo
Ibu-slow
Ibubest
Ibubeta
Ibucasen
Ibudol
Ibudolor
Ibufen
Ibuflamar
Ibufug
Ibugel
Ibugen
Ibugesic
Ibuhexal
 
Ibulagic
Ibular
Ibulav
Ibuleve
Ibulgan
Ibumed
Ibumerck
Ibumetin
Ibupirac
Ibuprin
Ibuprocin
Ibuprofen
Ibuprofen (NSAID) Pain Releiver/ Fever Reducer
Ibuprofen (nsaid) Pain Reliever/fever Reducer
Ibuprofen 200
Ibuprofen Caplet
Ibuprofen Childrens
Ibuprofen Dye-Free
Ibuprofen IMMEDIATE RELEASE
Ibuprofen Ib
Ibuprofen Immediate release
Ibuprofen Infants
Ibuprofen Junior
Ibuprofen Junior Strength
Ibuprofen Pain Releiver/ Fever Reducer
Ibuprofen Pain Reliever/ Fever Reducer
Ibuprofen Pain Reliever/Fever Reducer
Ibuprofen Pain Reliever/fever Reducer
Ibuprofen Softgels
Ibuprofen childrens
Ibuprofen infants
Ibuprofen junior strength
Ibuprofene
Ibuprofeno
Ibuprofenum
Ibuprohm
Ibuprophen
Ibusal
Ibutab
Ibutid
Ifen
Inabrin
Infants Advil
Infants Dye-free Ibuprofen
Infants Ibuprofen
Infants Motrin
Inflam
Inoven
Ipren
Irfen
Isodol
Jenaprofen
Junifen
Junior Strength Advil
Junior Strength Ibuprofen
Junior Strength Motrin
KBio1_000887
KBio2_001329
KBio2_003897
KBio2_006465
KBio3_001390
Kesan
Kirkland Signature Ibuprofen
Kirkland Signature Ibuprofen Ib
Kratalgin
LS-7454
Lamidon
Leader Childrens Ibuprofen
Leader Ibuprofen
Leader Ibuprofen 200
Leader Ibuprofen Childrens
Leader Ibuprofen Infants
Lebrufen
Librofem
Lidifen
Lil Drug Store Ibuprofen
Liptan
Lopane
MLS000069733
MLS001146965
Major Childrens Ibuprofen
Malafene
Manypren
Medi-first Ibuprofen
Medi-first Plus Ibuprofen
Medipren
Medique Iprin
Melfen
Mensoton
Midol
Midol 200
Moment
Moore Medical Llc Ibuprofen
Motrin
Motrin (TN)
Motrin IB
Motrin Ib
Motrin Infants
Mynosedin
NCI60_002065
NINDS_000887
NSC 256857
NSC256857
Nagifen-D
Napacetin
Narfen
Neo-Helvagit
Neo-Mindol
NeoProfen
Neobrufen
Neoprofen
Nerofen
Noalgil
Nobafon
Nobfelon
Nobfen
Nobgen
Noritis
Norton
Novadol
Novo-Profen
Novogent
Novogent N
Novoprofen
Nuprilan
Nuprin
Nurofen
Optifen
Opturem
Oralfene
Ostarin
Ostofen
Otis Clapp Ultraprin
Ozonol
P-Isobutylhydratropic Acid
Paduden
Pain Relief
Pain Relief Anti Inflammatory
Pain Relief Ibuprofen
Panafen
Pantrop
Para-Isobutylhydratropic Acid
Paxofen
Pedia-Profen
PediaProfen
Pediacare Childrens
Pediacare Infants
Pediaprofen
Pediatric Advil
Perofen
Perrigo Ibuprofen
Physicianscare Ibuprofen
Preferred Plus Ibuprofen
Preferred Plus Ibuprofen 200
Proartinal
Probufen
Profen
Profen Ib
Profen Ib childrens
Profen Ib infants
Proflex
Proprinal
Provon
Quadrax
Quality Choice Ibuprofen 200
R.D. 13621
RD 13621
Rafen
Ranofen
Rebugen
Relcofen
Rexall Ibuprofen
Rhinadvil
Rofen
Roidenin
Rufen
Rufin
Rupan
Rx Act Ibuprofen
Rx Act Ibuprofen childrens
SAM002264619
SMR000058184
SPBio_000178
STK177358
Sadefen
Salivia
Salprofen
Seclodin
Sednafen
Seklodin
Seskafen
Shoprite Childrens Ibuprofen
Shoprite Ibuprofen
Shoprite Ibuprofen Ib
Shoprite Ibuprophen
Shoprite Infants Ibuprofen
Simply Right Ibuprofen
Siyafen
Smart Sense Ibuprofen
Smart Sense Ibuprofen gluten free
Smart Sense Ibuprofen infants
Solpaflex
Solufen
Stelar
Sugafen
Sunmark Ibuprofen
Sunmark Ibuprofen Ib
Sunmark Ibuprofen childrens
Sunmark Ibuprofen infants
Suprafen
Suspren
Syntofene
TL8001184
Tab-Profen
Tabalon
Tabalon 400
Tatanal
Tempil
Tofen
Togal N
Tonal
Topcare Childrens Ibuprofen
Topcare Ibuprofen
Topcare Ibuprofen Junior Strength
Topcare Ibuprofen childrens
Topcare Infants Ibuprofen
Trendar
U 18573
U-18,573
U-18573
UCB 79171
Unipron
Upfen
Uprofen
Urem
VUFB 9649
Welby Health Ibuprofen
Zafen
Zofen
alpha-(4-Isobutylphenyl)propionate
alpha-(4-Isobutylphenyl)propionic acid
alpha-(P-Isobutylphenyl)propionic acid
alpha-p-Isobutylphenylpropionate
alpha-p-Isobutylphenylpropionic acid
ibuprofen
p-Isobutyl-2-phenylpropionate
p-Isobutyl-2-phenylpropionic acid
p-Isobutylhydratropate
p-Isobutylhydratropic acid
12
Oxycodoneapproved, illicit, investigationalPhase 433376-42-65284603
Synonyms:
(-)-14-Hydroxydihydrocodeinone
(-)-Oxycodone
(5alpha)-14-hydroxy-17-methyl-3-(methyloxy)-4,5-epoxymorphinan-6-one
124-90-3 (hydrochloride)
14-Hydroxydihydrocodeinone
14-hydroxy-3-methoxy-17-methyl-4,5alpha-epoxymorphinan-6-one
25333-72-6 (Terephthalate)
4,5-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5.alpha.-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
4,5alpha-Epoxy-14-hydroxy-3-methoxy-17-methylmorphinan-6-one
76-42-6
AC-16043
AC1Q4DTG
BRN 0043446
C08018
CHEBI:7852
CHEMBL656
CID5284603
Combunox
D05312
DB00497
DEA No. 9143
Dihydro-14-hydroxycodeinone
Dihydrohydroxycodeinone
Dihydrohydroxycondeinone
Dihydrone
Dihydroxycodeinone
Dinarkon
Diphydrone
EINECS 200-960-2
Endine (Australia)
Endocet
Endodan
Endone
Eubine
Eubine [France]
Eucodal
Eucodalum
Eukodal
Eutagen
HSDB 3142
Hydroxycodeinon
LS-92148
MolPort-004-285-989
Morphinan-6-one, 4,5alpha-epoxy-14-hydroxy-3-methoxy-17-methyl- (8CI)
NSC 19043
NSC19043
Ossicodone
 
Ossicodone [DCIT]
Oxanest
Oxecta
Oxicodona
Oxicodona [INN-Spanish]
Oxicon
Oxicone
Oxiconum
Oxikon
OxyFAST
OxyIR
OxyNorm
Oxycodeinon
Oxycodeinone
Oxycodon
Oxycodone
Oxycodone (USAN/INN)
Oxycodone Concentrate
Oxycodone Hcl
Oxycodone Hydrochloride
Oxycodone [USAN:INN:BAN]
Oxycodone hydrochloride
Oxycodonum
Oxycodonum [INN-Latin]
Oxycon
Oxycone
Oxycontin
Oxyfast
Oxynorm
PTI-821
Pancodine
Pancodone retard (United Kingdom)
Percobarb
Percodan
Percolone
Remoxy
Roxicet
Roxicodone
Supendol
Supendol [Canada]
Supeudol
Tecodin
Tekodin
Tekodin (free base)
Thecodine
Thekodin
Theocodin
UNII-CD35PMG570
WLN: T B6566 B6/CO 4ABBC R BX FV HO PN GHT&&TTJ CQ JO1 P1
oxycodone
13
Sufentanilapproved, investigationalPhase 415356030-54-741693
Synonyms:
56030-54-7
60561-17-3 (citrate)
AC1L26AJ
AC1Q5I7B
C08022
C22H30N2O2S
CHEBI:127638
CHEBI:9316
CHEMBL658
CID41693
Chronogesic
D05938
DB00708
HSDB 6760
L000580
LS-175693
MolPort-004-286-008
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-N-phenylpropanamide
N-(4-(Methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilide
 
N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide
N-{4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
N-{4-[(methyloxy)methyl]-1-[2-(2-thienyl)ethyl]piperidin-4-yl}-N-phenylpropanamide
Oprea1_120838
Oprea1_246787
PDSP1_001741
PDSP2_001724
R 30730
R-30730
SUFENTANIL
Sufentanil
Sufentanil (USAN/INN)
Sufentanil Citrate
Sufentanil [USAN:BAN:INN]
Sufentanilo
Sufentanilum
Sufentanilum [INN-Latin]
Sufentanyl
Sulfentanil
Sulfentanyl
UNII-AFE2YW0IIZ
14
Heroinapproved, illicitPhase 4109561-27-35462328
Synonyms:
(5alpha,6alpha)-7,8-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate (ester)
3,6-Diacetylmorphine
7,8-Dihydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol diacetate
Heroin
 
Heroin hydrochloride
O,O'-diacetylmorphine
Smack
diacetylmorphine
diamorphine
morphine diacetate
15Respiratory System AgentsPhase 43931
16Adrenergic AgentsPhase 4, Phase 3, Phase 24204
17Analgesics, OpioidPhase 4, Phase 3, Phase 22304
18NarcoticsPhase 4, Phase 3, Phase 22709
19Anti-Inflammatory AgentsPhase 4, Phase 28478
20Adrenergic AgonistsPhase 4, Phase 3, Phase 22331
21Adrenergic alpha-2 Receptor AgonistsPhase 4, Phase 3, Phase 2790
22Neurotransmitter AgentsPhase 4, Phase 3, Phase 214795
23Hypnotics and SedativesPhase 4, Phase 3, Phase 22032
24AnalgesicsPhase 4, Phase 3, Phase 29358
25Adrenergic alpha-AgonistsPhase 4, Phase 3, Phase 21300
26Peripheral Nervous System AgentsPhase 4, Phase 3, Phase 218510
27Anesthetics, IntravenousPhase 4, Phase 3, Phase 21943
28Antitussive AgentsPhase 4425
29Anesthetics, LocalPhase 4, Phase 3, Phase 22347
30Ketorolac TromethaminePhase 4278
31Central Nervous System DepressantsPhase 4, Phase 3, Phase 210016
32Chlorpheniramine, phenylpropanolamine drug combinationPhase 4512
33Anesthetics, GeneralPhase 4, Phase 3, Phase 22274
34AnestheticsPhase 4, Phase 3, Phase 27385
35Analgesics, Non-NarcoticPhase 4, Phase 3, Phase 25184
36Excitatory Amino AcidsPhase 41109
37Excitatory Amino Acid AntagonistsPhase 41095
38RacepinephrinePhase 4834
39Pharmaceutical SolutionsPhase 47004
40CarticainePhase 422
41Epinephryl boratePhase 4834
42Antirheumatic AgentsPhase 4, Phase 28496
43Cyclooxygenase InhibitorsPhase 4, Phase 22225
44Anti-Inflammatory Agents, Non-SteroidalPhase 4, Phase 23549
45TeaNutraceuticalPhase 4295
46
NalbuphineapprovedPhase 32520594-83-65360630, 5311304
Synonyms:
(5alpha,6alpha)-17-(cyclobutylmethyl)-4,5-epoxymorphinan-3,6,14-triol
17-cyclobutylmethyl-4,5alpha-epoxymorphinan-3,6alpha,14-triol
20594-83-6
BIDD:GT0060
BPBio1_000150
BRD-K66404838-003-03-8
BSPBio_000136
C07251
CHEBI:7454
CHEMBL895
CID5311304
D08246
HMS2089I04
Intapan
 
Intapan (TN)
N-Cyclobutylmethyl-4,5alpha-epoxy-3,6alpha,14-morphinantriol
Nalbufina
Nalbuphin
Nalbuphine
Nalbuphine (INN)
Nalbuphine Hydrochloride
Nalbuphine hydrochloride
Nalbuphinum
Prestwick0_000118
Prestwick1_000118
Prestwick2_000118
Prestwick3_000118
SPBio_002075
nalbuphine
47pancreatic polypeptidePhase 320
48Liver ExtractsPhase 33572
49ColaNutraceuticalPhase 31768
50
ClonidineapprovedPhase 21894205-90-72803
Synonyms:
1H-Imidazol-2-amine, N-(2,6-dichlorophenyl)-4,5-dihydro- (9CI)
2,6-Dichloro-N-2-imidazolidinylidenebenzenamine
2,6-dichloro-N-(2-imidazolidinylidene)aniline
2,6-dichloro-N-2-imidazolidinylidenebenzenamide
2,6-dichloro-N-imidazolidin-2-ylideneaniline
2-((2,6-Dichlorophenyl)imino)imidazolidine
2-(2,6-Dichloroanilino)-1,3-diazacyclopentene-(2)
2-(2,6-Dichloroanilino)-2-imidazoline
2-(2,6-Dichlorophenylamino)-2-imidazoline
2-(2,6-Dichlorophenylimino)imidazolidine
2-Imidazoline, 2-(2,6-dichloroanilino)- (7CI,8CI)
2-[(2,6-Dichlorophenyl)imino]imidazoline
2-[(2,6-dichlorophenyl)imino]-2-imidazoline
4205-90-7
4205-91-8 (mono-hydrochloride)
57066-25-8
734571A
AB00514634
AC1L1EI5
AC1Q3K6V
AKOS001595470
Adesipress
BIDD:GT0547
BPBio1_000040
BRD-K98530306-001-02-1
BRD-K98530306-003-05-0
BSPBio_000036
BSPBio_001588
BSPBio_002055
Bio1_000470
Bio1_000959
Bio1_001448
Bio2_000308
Bio2_000788
C9H9Cl2N3
CAS-4205-91-8
CATAPRES-TTS-1
CATAPRES-TTS-2
CATAPRES-TTS-3
CCRIS 7787
CHEBI:3757
CHEBI:46632
CHEMBL134
CID2803
Catapres
Catapres- TTS
Catapres-TTS
Catapresan
Catapressan
Catarpres
Catarpres-TTS
Catarpres-TTS (TN)
Catarpresan
Chlofazoline
Chlornidinum
Clofenil
Clonidin
Clonidina
Clonidina [INN-Spanish]
Clonidine
Clonidine (JAN/USAN/INN)
Clonidine HCl
Clonidine Hydrochloride
Clonidine Transdermal System
Clonidine [USAN:BAN:INN]
Clonidinhydrochlorid
Clonidinum
Clonidinum [INN-Latin]
Clonistada
Clopheline
D00281
DB00575
DB07566
DivK1c_000774
 
Dixarit
Duraclon
Duraclont
EINECS 224-119-4
Gemiton
HMS1361P10
HMS1791P10
HMS1989P10
HMS2089G11
HSDB 3040
Hemiton
IDI1_000774
IDI1_034058
Ipotensium
Isoglaucon
KBio1_000774
KBio2_000308
KBio2_001821
KBio2_002876
KBio2_004389
KBio2_005444
KBio2_006957
KBio3_000615
KBio3_000616
KBio3_001275
KBioGR_000308
KBioGR_001572
KBioSS_000308
KBioSS_001821
Kapvay
Klofelin
Klofenil
L000193
LS-79606
Lopac-C-7897
Lopac0_000268
M 5041T
M-5041T
MolPort-001-779-668
MolPort-005-932-374
N-(2,6-Dichlorophenyl)-4,5-dihydro-1H-imidazol-2-amine
NCGC00015268-01
NCGC00015268-02
NCGC00015268-08
NCGC00024734-01
NCGC00024734-02
NCGC00024734-03
NCGC00024734-04
NCGC00024734-05
NCGC00179680-01
NINDS_000774
Nexiclon
Nexiclon Xr
Prestwick0_000248
Prestwick1_000248
Prestwick2_000248
Prestwick3_000248
SKF 34427
SPBio_001233
SPBio_002255
ST 155BS
ST-155-BS
ST-155BS
Spectrum2_001187
Spectrum3_000358
Spectrum4_000956
Spectrum5_000759
Spectrum_001341
T171
Tenso-Timelets
Tocris-0690
UNII-MN3L5RMN02
ZINC00896484
clonidine
nchembio.79-comp11
nchembio705-10

Interventional clinical trials:

(show all 41)
idNameStatusNCT IDPhase
1Double Blind Randomized Study Into the Efficacy of Codeine Phosphate Analgesia After Cleft Palate Repair in InfantsCompletedNCT00386269Phase 4
2Comparison of IV PCA and Wound Infusion After Repair of Pectus ExcavatumCompletedNCT01908491Phase 4
3Sub-Paraspinal Block in Nuss Patients. A Pilot ProjectCompletedNCT02169297Phase 4
4Pudendal Block Versus Caudal Block for HypospadiasCompletedNCT02390388Phase 4
5Post Operative Pain Control Using Ropivacaine and the ON-Q System in the Adult Pectus Excavatum Patient After Minimally Invasive RepairCompletedNCT01816477Phase 4
6A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excuvatum RepairRecruitingNCT02056301Phase 4
7Comparison of the Local Anaesthetics Articaine and Bupivacaine in Treatment of Acute Sternum Pain After Heart SurgeryRecruitingNCT01536717Phase 4
8Ultrasound Guided Intermediate Cervical Plexus Block for Congenital Muscular TorticollisNot yet recruitingNCT02651311Phase 4
9Effect of Dexmedetomidine Combined With Sufentanil for Postoperative Intravenous Analgesia in NeurosurgeryNot yet recruitingNCT02552459Phase 4
10Ibuprofen and Opioid (Morphine or Diamorphine) for Acute Pain in Sickle Cell Disease - Sickle With Ibuprofen & MorphineTerminatedNCT00880373Phase 4
11Assessment of Opioid Analgesia in Sickle CellWithdrawnNCT00513864Phase 4
12Effects of Additional Fentanyl to Epidural Bupivacaine for Post-Thoracotomy Pain in NeonatesCompletedNCT00286143Phase 3
13Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer PainCompletedNCT00538850Phase 3
14Dexmedetomidine Infusion in Hypospadias SurgeryCompletedNCT00926705Phase 3
15Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates EquallyActive, not recruitingNCT01380197Phase 3
16THE IMPROVE TRIAL: Improving Pain Management and Outcomes With Various Strategies of Patient-Controlled Analgesia (PCA)TerminatedNCT00999245Phase 3
17Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in ChildrenCompletedNCT01701778Phase 2
18Association of Different Doses of Clonidine in Caudal Epidural Anesthesia for Hypospadias SurgeryCompletedNCT02769390Phase 2
19Nitrous Oxide Analgesia Vaso-occlusive CrisisRecruitingNCT01891812Phase 2
20A Study of Norepinephrine in Patients With Congenital Insensitivity to Pain and AnhidrosisWithdrawnNCT02624310Phase 2
21Comparison of Patient Controlled Analgesia (PCA) Versus Bolus Narcotic Therapy for the Treatment of Vaso-Occlusive Crisis (VOC)WithdrawnNCT00711698Phase 2
22Abciximab (ReoPro) as a Therapeutic Intervention for Sickle Cell Vaso-Occlusive Pain CrisisWithdrawnNCT01932554Phase 2
23Comparison of Levobupivacaine, Ropivacaine and Bupivacaine in Epidural AnaesthesiaCompletedNCT02513433
24Review of Pain Management After Congenital Cardiac SurgeryCompletedNCT01378663
25Comparison of Dexamethasone Added to Ropivacaine and Ropivacaine Alone in Caudal Analgesia in Children Undergoing OrchiopexyCompletedNCT01604915
26Pain Management for Pectus Excavatum RepairCompletedNCT00413582
27Prediction and Characterization of Acute and Chronic Postoperative PainCompletedNCT01308385
28Assessing Function in Pediatric Patients With Sickle Cell DiseaseCompletedNCT00590148
29The Caudal Space in Children: Ultrasound EvaluationCompletedNCT01896076
30Effectiveness of New Analgesic Strategy Compared to the Usal Antalgic StrategyCompletedNCT00874172
31Painful Channelopathies StudyRecruitingNCT02696746
32SPAIN Chest Wall Deformity Project (Pectus Repair)RecruitingNCT02098681
33Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain CrisesRecruitingNCT02573714
34A Randomised Trial Comparing Supraclavicular Block vs Supraclavicular and Pecs II Block in Arteriovenous GraftingRecruitingNCT02331030
35Subcapsular Orchiectomy in Men With Klinefelter SyndromeRecruitingNCT01750632
36Nuss Procedure: Clinical Options in Pediatric Pain Management?Active, not recruitingNCT02009267
37The Management of Postoperative Craniotomy Pain in Pediatric PatientsEnrolling by invitationNCT01576601
38Sucrose Analgesia in Infants Undergoing Casting for Club FootNot yet recruitingNCT01050088
39The Effect of Gender on the Consumption of Pain Medication in Infants Undergoing Craniosynostosis Repair or Untethering of Cord in ITUNot yet recruitingNCT01996163
40A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive CrisesNot yet recruitingNCT02698761
41Analgesic Strategies in Newborns Receiving Prostaglandin TherapyTerminatedNCT00200590

Search NIH Clinical Center for Neuropathy, Hereditary Sensory and Autonomic, Type V


Cochrane evidence based reviews: pain insensitivity, congenital

Genetic Tests for Neuropathy, Hereditary Sensory and Autonomic, Type V

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Genetic tests related to Neuropathy, Hereditary Sensory and Autonomic, Type V:

id Genetic test Affiliating Genes
1 Congenital Indifference to Pain, Autosomal Recessive22 SCN9A
2 Hereditary Sensory and Autonomic Neuropathy Type V22 NGF

Anatomical Context for Neuropathy, Hereditary Sensory and Autonomic, Type V

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MalaCards organs/tissues related to Neuropathy, Hereditary Sensory and Autonomic, Type V:

33
Bone, Tongue, Heart, Liver

Animal Models for Neuropathy, Hereditary Sensory and Autonomic, Type V or affiliated genes

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MGI Mouse Phenotypes related to Neuropathy, Hereditary Sensory and Autonomic, Type V:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00028738.9NGF, NTRK1, SCN9A
2MP:00107718.9NGF, NTRK1, SCN9A

Publications for Neuropathy, Hereditary Sensory and Autonomic, Type V

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Variations for Neuropathy, Hereditary Sensory and Autonomic, Type V

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UniProtKB/Swiss-Prot genetic disease variations for Neuropathy, Hereditary Sensory and Autonomic, Type V:

67
id Symbol AA change Variation ID SNP ID
1NGFp.Arg221TrpVAR_030659rs11466112
2SCN9Ap.Arg907GlnVAR_064610

Clinvar genetic disease variations for Neuropathy, Hereditary Sensory and Autonomic, Type V:

5
id Gene Variation Type Significance SNP ID Assembly Location
1NGFNM_002506.2(NGF): c.661C> T (p.Arg221Trp)single nucleotide variantPathogenicrs11466112GRCh37Chr 1, 115828756: 115828756
2NM_002977.3(SCN9A): c.3993delGinsTT (p.Leu1331Phefs)indelPathogenicrs606231279GRCh37Chr 2, 167085381: 167085381
3NM_002977.3(SCN9A): c.2690G> A (p.Trp897Ter)single nucleotide variantPathogenicrs794729216GRCh37Chr 2, 167133644: 167133644
4NGFNGF, 680C-A AND 2-BP DEL, 681GGdeletionPathogenic
5NM_002977.3(SCN9A): c.1376C> G (p.Ser459Ter)single nucleotide variantPathogenicrs121908908GRCh37Chr 2, 167143072: 167143072
6SCN9ASCN9A, 1-BP DEL, 2298TdeletionPathogenic
7NM_002977.3(SCN9A): c.2691G> A (p.Trp897Ter)single nucleotide variantPathogenicrs121908909GRCh37Chr 2, 167133643: 167133643
8SCN9ANM_002977.3(SCN9A): c.829C> T (p.Arg277Ter)single nucleotide variantPathogenicrs121908916GRCh37Chr 2, 167159672: 167159672
9NM_002977.3(SCN9A): c.984C> A (p.Tyr328Ter)single nucleotide variantPathogenicrs121908917GRCh37Chr 2, 167149864: 167149864

Expression for genes affiliated with Neuropathy, Hereditary Sensory and Autonomic, Type V

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Search GEO for disease gene expression data for Neuropathy, Hereditary Sensory and Autonomic, Type V.

Pathways for genes affiliated with Neuropathy, Hereditary Sensory and Autonomic, Type V

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GO Terms for genes affiliated with Neuropathy, Hereditary Sensory and Autonomic, Type V

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Biological processes related to Neuropathy, Hereditary Sensory and Autonomic, Type V according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.7NGF, NTRK1
2activation of phospholipase C activityGO:00072029.6NGF, NTRK1
3sensory perception of painGO:00192339.1NTRK1, SCN9A
4small GTPase mediated signal transductionGO:00072649.0NGF, NTRK1

Sources for Neuropathy, Hereditary Sensory and Autonomic, Type V

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet