MCID: NRS005
MIFTS: 23

Neurosarcoidosis malady

Category: Neuronal diseases

Aliases & Classifications for Neurosarcoidosis

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Aliases & Descriptions for Neurosarcoidosis:

Name: Neurosarcoidosis 49 68

Classifications:



Summaries for Neurosarcoidosis

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NINDS:49 Neurosarcoidosis is a manifestation of sarcoidosis in the nervous system.  Sarcoidosis is a chronic inflammatory disorder that typically occurs in adults between 20 and 40 years of age and primarily affects the lungs, but can also impact almost every other organ and system in the body.  Neurosarcoidosis is characterized by inflammation and abnormal cell deposits in any part of the nervous system – the brain, spinal cord, or peripheral nerves.  It most commonly occurs in the cranial and facial nerves, the hypothalamus (a specific area of the brain), and the pituitary gland.  It is estimated to develop in 5 to 15 percent of those individuals who have sarcoidosis.  Weakness of the facial muscles on one side of the face (Bell’s palsy) is a common symptom of neurosarcoidosis.  The optic and auditory nerves can also become involved, causing vision and hearing impairments.  It can cause headache, seizures, memory loss, hallucinations, irritability, agitation, and changes in mood and behavior.  Neurosarcoidosis can appear in an acute, explosive fashion or start as a slow chronic illness.  Because neurosarcoidosis manifests in many different ways, a diagnosis may be difficult and delayed.

MalaCards based summary: Neurosarcoidosis is related to hydrocephalus and meningitis. An important gene associated with Neurosarcoidosis is ACE (Angiotensin I Converting Enzyme). Affiliated tissues include brain, lung and spinal cord.

Wikipedia:71 Neurosarcoidosis (sometimes shortened to neurosarcoid) refers to sarcoidosis, a condition of unknown... more...

Related Diseases for Neurosarcoidosis

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Graphical network of the top 20 diseases related to Neurosarcoidosis:



Diseases related to neurosarcoidosis

Symptoms & Phenotypes for Neurosarcoidosis

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Drugs & Therapeutics for Neurosarcoidosis

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Drugs for Neurosarcoidosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1Hormones, Hormone Substitutes, and Hormone Antagonists13168
2Melanocyte-Stimulating Hormones139
3Hormones14415
4Hormone Antagonists13180
5beta-endorphin140
6Adrenocorticotropic Hormone164

Interventional clinical trials:

idNameStatusNCT IDPhase
1Analysis of the Distribution of Regulatory B Cells in Blood of Multiple Sclerosis PatientsRecruitingNCT02789670
2ACTHAR Therapy for Central Nervous System SarcoidosisNot yet recruitingNCT02920710

Search NIH Clinical Center for Neurosarcoidosis

Genetic Tests for Neurosarcoidosis

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Anatomical Context for Neurosarcoidosis

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MalaCards organs/tissues related to Neurosarcoidosis:

36
Brain, Lung, Spinal cord, Pituitary, Testes, Hypothalamus, Pineal

Publications for Neurosarcoidosis

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Articles related to Neurosarcoidosis:

(show top 50)    (show all 440)
idTitleAuthorsYear
1
Isolated neurosarcoidosis presenting with multiple cranial nerve palsies. (27168947)
2016
2
Neurosarcoidosis Presenting as Aseptic Meningitis in an Immunosuppressed Renal Transplant Recipient. (26863472)
2016
3
Intractable Neurosarcoidosis Effectively Treated with Infliximab. (27041170)
2016
4
NEUROSARCOIDOSIS MASQUERADING AS A CENTRAL NERVOUS SYSTEM TUMOR. (27571425)
2016
5
The devil is in the detail: Acute Guillain-BarrAc syndrome camouflaged as neurosarcoidosis in a critically ill patient admitted to an Intensive Care Unit. (27303139)
2016
6
Unusual Presentation of Central Diabetes Insipidus in a Patient With Neurosarcoidosis. (27652275)
2016
7
Poster 348 Biospy-Confirmed Neurosarcoidosis Manifesting as a Non-Compressive Myelopathy with Transverse Myelitis and Normal ACE Level: A Case Study. (27673101)
2016
8
Neurosarcoidosis in Pediatric Patients: A Case Report and Review of Isolated and Systemic Neurosarcoidosis. (27524272)
2016
9
Teaching NeuroImages: Recurrent oculomotor palsies caused by neurosarcoidosis. (27432184)
2016
10
Neurosarcoidosis in a Tertiary Referral Center: A Cross-Sectional Cohort Study. (27057889)
2016
11
Isolated Central Nervous System Vasculitis as a Manifestation of Neurosarcoidosis. (27083067)
2016
12
Neurosarcoidosis. (26593139)
2015
13
Gasserian ganglion neurosarcoidosis mimicking trigeminal schwannoma. (25742592)
2015
14
Endoscopic biopsy for the diagnosis of neurosarcoidosis at the fourth ventricle outlet with hydrocephalus. (26682088)
2015
15
Corticosteroid-resistant bulbar neurosarcoidosis responsive to intravenous immunoglobulin. (25935926)
2015
16
Challenges in the diagnosis and treatment of neurosarcoidosis. (26469296)
2015
17
Neurosarcoidosis as an MS Mimic: The trials and tribulations of making a diagnosis. (26346790)
2015
18
Neurosarcoidosis mimicking bilateral posterior fossa tentorial meningiomas. (26341372)
2015
19
Effects of fatigue on cognitive control in neurosarcoidosis. (25700944)
2015
20
Neurosarcoidosis: diagnosis, therapy and biomarkers. (25936846)
2015
21
Girdle Sensation Caused by Radiculitis due to Neurosarcoidosis. (26073252)
2015
22
Spinal cord hemorrhage in a patient with neurosarcoidosis on long-term corticosteroid therapy: case report. (26224095)
2015
23
Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients. (26478897)
2015
24
Neurosarcoidosis-associated central diabetes insipidus masked by adrenal insufficiency. (25612752)
2015
25
Hashimoto encephalopathy or neurosarcoidosis? A case report. (25829987)
2015
26
Hypocretin Deficiency Associated with Narcolepsy Type 1 and Central Hypoventilation Syndrome in Neurosarcoidosis of the Hypothalamus. (25979096)
2015
27
Images in clinical medicine. Hemichoreoathetosis in neurosarcoidosis. (25992763)
2015
28
A rare comorbidity: neurosarcoidosis and cutaneous sarcoidosis. (26578505)
2015
29
The use of cladribine in neurosarcoidosis: A report of two cases. (26073679)
2015
30
Longitudinal ultra-extensive transverse myelitis as a manifestation of neurosarcoidosis. (26027786)
2015
31
The intrathecal, polyspecific antiviral immune response in neurosarcoidosis, acute disseminated encephalomyelitis and autoimmune encephalitis compared to multiple sclerosis in a tertiary hospital cohort. (26652013)
2015
32
A case of neurosarcoidosis secondary to treatment of etanercept and review of the literature. (26150616)
2015
33
A CASE OF PROBABLE NEUROSARCOIDOSIS PRESENTING AS UNILATERAL OPHTHALMOPLEGIA. (26666108)
2015
34
Neurosarcoidosis presenting as status epilepticus: a new bronchoscopic complication. (25887017)
2015
35
Vertigo as a predominant manifestation of neurosarcoidosis. (25922606)
2015
36
A case of relapsing neurosarcoidosis with brain nodules and hydrocephalus successfully treated by corticosteroid and methotrexate. (25957441)
2015
37
Cerebrospinal fluid angiotensin-converting enzyme for diagnosis of neurosarcoidosis. (26198911)
2015
38
1260: NEUROSARCOIDOSIS INDUCED PANHYPOPITUITARISM. (26570921)
2015
39
Isolated neurosarcoidosis mimicking intracranial tumours - Analysis of 3 cases. (25773910)
2015
40
An unusual cause of sudden hearing loss. Probable neurosarcoidosis (NS). (25375245)
2015
41
Nemesis of neglected neurosarcoidosis. (26478894)
2015
42
Imaging of neurosarcoidosis: common, uncommon, and rare. (26506463)
2015
43
Neurosarcoidosis: clinical review of a disorder with challenging inpatient presentations and diagnostic considerations. (24707339)
2014
44
Modulatory effects of proinflammatory cytokines for action cascading processes - evidence from neurosarcoidosis. (24846477)
2014
45
A case of neurosarcoidosis with labyrinthine involvement. (24744945)
2014
46
Intracranial hemorrhage in neurosarcoidosis. (24735739)
2014
47
Bilateral sensorineural hearing loss and labyrinthitis ossificans secondary to neurosarcoidosis. (25189997)
2014
48
Isolated dysphagia unmasking bulbar neurosarcoidosis and pulmonary sarcoidosis. (25097053)
2014
49
Overnight response to infliximab in neurosarcoidosis: a case report and review of infliximab treatment practice. (25229171)
2014
50
Oculopalatal tremor, facial myokymia and truncal ataxia in a patient with neurosarcoidosis. (25103854)
2014

Variations for Neurosarcoidosis

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Expression for genes affiliated with Neurosarcoidosis

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Search GEO for disease gene expression data for Neurosarcoidosis.

Pathways for genes affiliated with Neurosarcoidosis

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GO Terms for genes affiliated with Neurosarcoidosis

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Sources for Neurosarcoidosis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet