MCID: NRS005
MIFTS: 35

Neurosarcoidosis malady

Neuronal diseases category
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Summaries for Neurosarcoidosis

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Wikipedia:65 Neurosarcoidosis (sometimes shortened to neurosarcoid) refers to sarcoidosis, a condition of unknown... more...

MalaCards based summary: Neurosarcoidosis is related to sarcoidosis and pulmonary sarcoidosis. An important gene associated with Neurosarcoidosis is ACE (angiotensin I converting enzyme), and among its related pathways is Toll-like receptor signaling pathway. The compound nitric oxide have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and testes, and related mouse phenotypes are tumorigenesis and liver/biliary system.

NINDS:43 Neurosarcoidosis is a manifestation of sarcoidosis in the nervous system.

Aliases & Classifications for Neurosarcoidosis

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Neurosarcoidosis, Aliases & Descriptions:

Name: Neurosarcoidosis 43 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Related Diseases for Neurosarcoidosis

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Graphical network of the top 20 diseases related to Neurosarcoidosis:



Diseases related to neurosarcoidosis

Symptoms for Neurosarcoidosis

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Drugs & Therapeutics for Neurosarcoidosis

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Drug clinical trials:

Search ClinicalTrials for Neurosarcoidosis

Search NIH Clinical Center for Neurosarcoidosis

Genetic Tests for Neurosarcoidosis

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Anatomical Context for Neurosarcoidosis

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MalaCards organs/tissues related to Neurosarcoidosis:

32
Spinal cord, Brain, Testes, Lung, Pituitary, Pineal, Endothelial, Medulla oblongata, Lymph node, Heart, Breast, Hypothalamus

Animal Models for Neurosarcoidosis or affiliated genes

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MGI Mouse Phenotypes related to Neurosarcoidosis:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.2ACE, IFNG
2MP:00053709.1ACE, IFNG
3MP:00053899.1ACE, IFNG
4MP:00053679.0IFNG, ACE
5MP:00053798.8ACE, IFNG

Publications for Neurosarcoidosis

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Articles related to Neurosarcoidosis:

(show top 50)    (show all 389)
idTitleAuthorsYear
1
New brain lesions in a patient with sarcoidosis: is it neurosarcoidosis? (24751455)
2014
2
Isolated neurosarcoidosis in the medulla oblongata involving the fourth ventricle: a case report. (23167667)
2013
3
Neurosarcoidosis-related intracranial haemorrhage: three new cases and a systematic review of the literature. (22681045)
2013
4
Sequential peripheral neuropathy and myelopathy in a neurosarcoidosis patient. (23055107)
2013
5
i>?Neurosarcoidosis presenting as trigeminal nevralgia: a case report and review of the literature. (24071889)
2013
6
Neurosarcoidosis: clinical features, diagnosis, and management. (19092637)
2013
7
Infiltrative neurosarcoidosis presenting as secondary amenorrhea: case report and review of the literature. (23942474)
2013
8
Idiopathic hypertrophic pachymeningitis mimicking neurosarcoidosis. (22071202)
2012
9
Reply: Treatment of refractory neurosarcoidosis with tumour necrosis factor inhibitors--what lies ahead? (22498131)
2012
10
Detection of clinical and subclinical retinal abnormalities in neurosarcoidosis with optical coherence tomography. (22215236)
2012
11
Neurosarcoidosis and the complexity in its differential diagnoses: a review. (22666636)
2012
12
Bilateral vestibular hypofunction in neurosarcoidosis: a case report. (21229491)
2011
13
Magnetic resonance imaging of neurosarcoidosis. (21977388)
2011
14
Acute multiple cranial neuropathy in a patient with neurosarcoidosis. (20198497)
2010
15
Neurosarcoidosis and associated neuropsychological sequelae: a rare case of isolated intracranial involvement. (19953427)
2010
16
Neurosarcoidosis: an uncommon presentation. (20739827)
2010
17
Neuropsychological findings in a case of neurosarcoidosis. (20160243)
2010
18
Neurosarcoidosis presenting as spontaneously remitting hypersomnia. (19609590)
2009
19
Diffuse neurosarcoidosis involving only the leptomeninges of the brainstem and spinal cord. (19881245)
2009
20
Neurosarcoidosis: a study of 30 new cases. (18977817)
2009
21
Steroid-unresponsive neurosarcoidosis successfully treated with adalimumab. (19219574)
2009
22
Prognosis of refractory neurosarcoidosis altered by thalidomide: a case report. (18226232)
2008
23
Aggressive therapy for neurosarcoidosis: long-term follow-up of 48 treated patients. (17502468)
2007
24
Neurosarcoidosis in a patient with rheumatoid arthritis during treatment with infliximab. (17985415)
2007
25
Neurosarcoidosis. (17445493)
2007
26
Intracerebral bleeding in a patient with neurosarcoidosis while on corticosteroid therapy. (15898534)
2005
27
Neurosarcoidosis presenting with simple partial seizures and solitary enhancing mass: case reports and review of the literature. (15907759)
2005
28
Neurosarcoidosis: an unusual indication for radiotherapy. (15447966)
2004
29
Refractory neurosarcoidosis responding to infliximab. (12451224)
2002
30
CSF-ACE activity in probable CNS neurosarcoidosis. (12405488)
2002
31
Neurosarcoidosis presenting as psychosis and dementia: a case report. (12779189)
2002
32
Solitary intramedullary neurosarcoidosis: role of MRI in early detection. (11198533)
2001
33
The role of MRI and nerve root biopsy in the diagnosis of neurosarcoidosis. (11766780)
2001
34
Neurosarcoidosis diagnosed during pregnancy by thoracoscopic lymph node biopsy. A case report. (10948472)
2000
35
Extensive leptomeningeal and intraparenchymatous spinal cord neurosarcoidosis. (10963518)
2000
36
Neurosarcoidosis as a cause of refractory psychosis: a complicated case report. (9699702)
1998
37
Facial nerve enhancement on gadolinium-DTPA in a case with neurosarcoidosis. (9392359)
1997
38
Schizophrenia vs. neurosarcoidosis in a young male. (8742547)
1996
39
Familial neurosarcoidosis. (8551207)
1996
40
Endothelial cell damage in sarcoidosis and neurosarcoidosis: autoantibodies to endothelial cells. (7796836)
1995
41
Transient ischaemic attack, infectious meningitis, or neurosarcoidosis? (8552551)
1995
42
Therapeutic considerations in patients with refractory neurosarcoidosis. (7661724)
1995
43
Amnesic syndrome caused by neurosarcoidosis. (8344011)
1993
44
Probable case of neurosarcoidosis. (8300499)
1993
45
Neurosarcoidosis presenting as a tumour of the basal ganglia and brainstem: sequential MRI. (8099215)
1993
46
Local synthesis of specific IgG in the cerebrospinal fluid of patients with neurosarcoidosis detected by antigen immunoblotting using Kveim material. (2086723)
1990
47
Cerebrospinal fluid immunoglobulin abnormalities in neurosarcoidosis. (2919980)
1989
48
Depression and sexual dysfunction complicating neurosarcoidosis. (3469475)
1987
49
CSF angiotensin-converting enzyme in neurosarcoidosis. (2859505)
1985
50
Radiologic evaluation of neurosarcoidosis: role of computed tomography. (6814216)
1982

Variations for Neurosarcoidosis

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Expression for genes affiliated with Neurosarcoidosis

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Expression patterns in normal tissues for genes affiliated with Neurosarcoidosis

Search GEO for disease gene expression data for Neurosarcoidosis.

Pathways for genes affiliated with Neurosarcoidosis

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Pathways related to Neurosarcoidosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
9.1ACE, IFNG

Compounds for genes affiliated with Neurosarcoidosis

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Sources:
44Novoseek, 24HMDB, 11DrugBank
See all sources

Compounds related to Neurosarcoidosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1nitric oxide44 24 1111.1ACE, IFNG

GO Terms for genes affiliated with Neurosarcoidosis

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Cellular components related to Neurosarcoidosis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:0055769.1ACE, IFNG
2external side of plasma membraneGO:0098979.0ACE, IFNG
3extracellular spaceGO:0056158.8ACE, IFNG

Products for genes affiliated with Neurosarcoidosis

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  • Antibodies
  • Proteins
  • Lysates

Sources for Neurosarcoidosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet