MCID: NVD003
MIFTS: 18

Nevoid Hypermelanosis, Linear and Whorled malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Nevoid Hypermelanosis, Linear and Whorled

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Sources:
50OMIM, 46NIH Rare Diseases, 52Orphanet, 66UMLS, 67UMLS via Orphanet, 29ICD10 via Orphanet, 62The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Nevoid Hypermelanosis, Linear and Whorled:

Name: Nevoid Hypermelanosis, Linear and Whorled 50 46
Linear and Whorled Nevoid Hypermelanosis 46 52 66
Reticulate Hyperpigmentation of Iijima 46
Linear and Whorled Hypermelanosis 46
 
Zosteriform Hyperpigmentation 46
Zosteriform Lentiginous Nevus 46
Zebra-Like Hyperpigmentation 46
Lwnh 46

Characteristics:

HPO:

62
nevoid hypermelanosis, linear and whorled:
Inheritance: autosomal dominant inheritance
Onset and clinical course: infantile onset


Classifications:

Orphanet: 52 
Rare skin diseases


External Ids:

OMIM50 614323
Orphanet52 ORPHA79150
UMLS via Orphanet67 C1304501
ICD10 via Orphanet29 L81.4

Summaries for Nevoid Hypermelanosis, Linear and Whorled

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OMIM:50 Linear and whorled hypermelanosis (LWNH) is a benign skin condition characterized by onset in infancy of hyperpigmented... (614323) more...

MalaCards based summary: Nevoid Hypermelanosis, Linear and Whorled, also known as linear and whorled nevoid hypermelanosis, is related to ichthyosis vulgaris and cerebritis, and has symptoms including eosinophilia and hyperpigmented streaks. Affiliated tissues include skin.

NIH Rare Diseases:46 Linear and whorled nevoid hypermelanosis is a skin condition characterized by swirling streaks of hyperpigmented (darkened) skin. the hyperpigmentation follows the lines of blashko. the hyperpigmentation often occurs alone, but additional symptoms have been described in individual cases. its occurrence is nearly always sporadic. the cause of linear and whorled nevoid hypermelanosis is not known. last updated: 3/18/2013

Wikipedia:69 Linear and whorled nevoid hypermelanosis (also known as \"Linear nevoid hyperpigmentation,\"... more...

Related Diseases for Nevoid Hypermelanosis, Linear and Whorled

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Diseases related to Nevoid Hypermelanosis, Linear and Whorled via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1ichthyosis vulgaris10.3
2cerebritis10.3
3inflammatory linear verrucous epidermal nevus10.3
4aneurysm10.3
5cerebral aneurysms10.3

Graphical network of diseases related to Nevoid Hypermelanosis, Linear and Whorled:



Diseases related to nevoid hypermelanosis, linear and whorled

Symptoms for Nevoid Hypermelanosis, Linear and Whorled

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Symptoms by clinical synopsis from OMIM:

614323

Clinical features from OMIM:

614323

HPO human phenotypes related to Nevoid Hypermelanosis, Linear and Whorled:

id Description Frequency HPO Source Accession
1 eosinophilia HP:0001880
2 hyperpigmented streaks HP:0007572

Drugs & Therapeutics for Nevoid Hypermelanosis, Linear and Whorled

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Nevoid Hypermelanosis, Linear and Whorled

Genetic Tests for Nevoid Hypermelanosis, Linear and Whorled

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Anatomical Context for Nevoid Hypermelanosis, Linear and Whorled

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MalaCards organs/tissues related to Nevoid Hypermelanosis, Linear and Whorled:

34
Skin

Animal Models for Nevoid Hypermelanosis, Linear and Whorled or affiliated genes

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Publications for Nevoid Hypermelanosis, Linear and Whorled

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Variations for Nevoid Hypermelanosis, Linear and Whorled

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Expression for genes affiliated with Nevoid Hypermelanosis, Linear and Whorled

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Search GEO for disease gene expression data for Nevoid Hypermelanosis, Linear and Whorled.

Pathways for genes affiliated with Nevoid Hypermelanosis, Linear and Whorled

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GO Terms for genes affiliated with Nevoid Hypermelanosis, Linear and Whorled

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Sources for Nevoid Hypermelanosis, Linear and Whorled

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet