MCID: NVS007
MIFTS: 33

Nevus of Ota malady

Categories: Skin diseases, Rare diseases

Aliases & Classifications for Nevus of Ota

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Sources:
30ICD10 via Orphanet, 53Orphanet, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Nevus of Ota:

Name: Nevus of Ota 53
 
Nevus Fusculoceruleus Ophthalmomaxillaris 53

Characteristics:

Orphanet epidemiological data:

53
nevus fusculoceruleus ophthalmomaxillaris:
Inheritance: Not applicable; Age of onset: All ages

Classifications:

Orphanet: 53 
Rare skin diseases


External Ids:

Orphanet53 ORPHA263425
ICD10 via Orphanet30 D22.3
UMLS via Orphanet68 C0027961

Summaries for Nevus of Ota

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Wikipedia:70 Nevus of Ota (also known as \"congenital melanosis bulbi\", \"nevus fuscoceruleus ophthalmomaxillaris\",... more...

MalaCards based summary: Nevus of Ota, also known as nevus fusculoceruleus ophthalmomaxillaris, is related to phacomatosis pigmentovascularis and meningitis. An important gene associated with Nevus of Ota is BAP1 (BRCA1 Associated Protein 1), and among its related pathways are MAPK Signaling: Mitogen Stimulation Pathway and mTOR Pathway. Affiliated tissues include skin, eye and pineal, and related mouse phenotypes are embryo and muscle.

Related Diseases for Nevus of Ota

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Graphical network of the top 20 diseases related to Nevus of Ota:



Diseases related to nevus of ota

Symptoms for Nevus of Ota

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Drugs & Therapeutics for Nevus of Ota

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Drugs for Nevus of Ota (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
LiraglutideapprovedPhase 3315204656-20-2
Synonyms:
204656-20-2
Arg34Lys26-(N-ε-(γ-Glu(N-α-hexadecanoyl)))-GLP-1[7-37]
C439759
Liraglutida
Liraglutida [INN-Spanish]
Liraglutide
Liraglutide [USAN:INN]
Liraglutide recombinant
Liraglutidum
Liraglutidum [INN-Latin]
N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)GLP-1-(7-37)-peptide
 
N26-(Hexadecanoyl-gamma-glutamyle)-(34-arginine)glucagon-like-peptide-1-(7-37)-peptide
NN 2211
NN-2211
NN2211
NNC 90-1170
N²⁶-(N-Hexadecanoyl-L-gamma-glutamyl)-[34-L-arginine]glucagon-like peptide 1-(7-37)-peptide
N²⁶-(hexadecanoyl-gamma-glutamyle)-[34-arginine]GLP-1-(7-37)-peptide
UNII-839I73S42A
Victoza
nn 2211
nn2211
victoza
2Hormone AntagonistsPhase 312778
3Hypoglycemic AgentsPhase 35733
4IncretinsPhase 31537
5Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 312767
6HormonesPhase 313979
7Sitagliptin PhosphatePhase 3416
8
protease inhibitorsPhase 35320
Synonyms:
 
protease inhibitors
9Dipeptidyl-Peptidase IV InhibitorsPhase 3846
10HIV Protease InhibitorsPhase 35319

Interventional clinical trials:

idNameStatusNCT IDPhase
1Dose-response, Safety and Efficacy of Oral Semaglutide Versus Placebo and Versus Liraglutide, All as Monotherapy in Japanese Subjects With Type 2 DiabetesRecruitingNCT03018028Phase 3
2Efficacy and Long-term Safety of Oral Semaglutide Versus Sitagliptin in Subjects With Type 2 DiabetesActive, not recruitingNCT02607865Phase 3
3Optical Clearing of the Skin in Conjunction With Laser TreatmentsCompletedNCT00580736Phase 1
4Effect of Cold Air Cooling on the Incidence of Post Inflammatory Hyperpigmentation Following Laser TreatmentCompletedNCT00287001

Search NIH Clinical Center for Nevus of Ota

Genetic Tests for Nevus of Ota

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Anatomical Context for Nevus of Ota

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MalaCards organs/tissues related to Nevus of Ota:

35
Skin, Eye, Pineal, Brain

Animal Models for Nevus of Ota or affiliated genes

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MGI Mouse Phenotypes related to Nevus of Ota:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053809.3BAP1, BRAF, TP53
2MP:00053699.2BAP1, BRAF, TP53
3MP:00020068.5BAP1, BRAF, TP53

Publications for Nevus of Ota

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Articles related to Nevus of Ota:

(show top 50)    (show all 186)
idTitleAuthorsYear
1
Comparison of clinical efficacy and complications between Q-switched alexandrite laser and Q-switched Nd:YAG laser on nevus of Ota: a systematic review and meta-analysis. (26861980)
2016
2
An Orbital Malignant Melanoma Arising in Cellular Blue Nevus in a Patient with Nevus of Ota. (27699140)
2016
3
Nevus of Ota. (27734644)
2016
4
Primary melanoma of the leptomeninges with bap1 expression-loss in the setting of a nevus of ota: A clinical, morphological and genetic study of 2 cases. (26834043)
2016
5
A Retrospective Study on the Characteristics of Treating Nevus of Ota by 1064-nm Q-switched Neodymium-doped Yttrium Aluminum Garnet Laser. (27293272)
2016
6
Recurrence of Nevus of Ota after Successful Laser Treatment: Possible Role of Dermal Stem Cells. (27746651)
2016
7
Factors affecting response and laser sessions and complications in Nevus of Ota treated by Q- switched alexandrite laser: A retrospective study. (25747257)
2015
8
Acquired Bilateral Nevus of ota-like Macules with Mucosal Involvement: A New Variant of Hori's Nevus. (24891664)
2014
9
Nevus of ota. (24986303)
2014
10
Unilateral open-angle glaucoma associated with the ipsilateral nevus of ota. (23781367)
2013
11
Orbital malignant melanoma associated with nevus of Ota. (23571263)
2013
12
Malignant melanoma from a nevus of Ota in a pediatric patient with fatal outcome. (24034399)
2013
13
Are Q-switched lasers for Nevus of Ota really effective in pigmented skin? (22421653)
2012
14
Report of rare palatal expression of Nevus of Ota with amendment of Tanino's classification. (22484884)
2011
15
A retrospective study of q-switched alexandrite laser in treating nevus of ota. (21790845)
2011
16
Intracranial meningeal melanocytoma associated with nevus of Ota. (21924617)
2011
17
Q-Switched Nd:YAG Laser Therapy of Acquired Bilateral Nevus of Ota-like Macules. (20523799)
2009
18
Nevus of Ota in children. (18712021)
2008
19
Centrally located acquired bilateral nevus of Ota-like macules (Hori's nevus): is this a novel type? (18779111)
2008
20
Effect of cold air cooling on the incidence of postinflammatory hyperpigmentation after Q-switched Nd:YAG laser treatment of acquired bilateral nevus of Ota like macules. (17875874)
2007
21
Contralaterally spreading type III nevus of Ota in a white person. (17448000)
2007
22
Acquired bilateral nevus of Ota-like macules. (16403373)
2005
23
Recurrent intracranial melanocytoma associated with a nevus of Ota. (15618991)
2005
24
Comparison of characteristics of acquired bilateral nevus of Ota-like macules and nevus of Ota according to therapeutic outcome. (15308847)
2004
25
Oculodermal melanocytosis--Nevus of Ota (with palatal pigmentation). (15328990)
2003
26
Falsely elevated intraocular pressure due to an abnormally thick cornea in a patient with nevus of Ota. (12738546)
2003
27
Bilateral nevus of ota with oral mucosal involvement. (17656896)
2002
28
Are these pigmentary changes only cosmetic? Oculodermal melanocytosis (nevus of Ota). (11787407)
2001
29
Changes of biophysical properties of the skin measured by non-invasive techniques after Q-switched Nd-YAG laser therapy in patients with nevus of Ota. (11737822)
2001
30
Clinical use of the Q-switched Nd:YAG laser for the treatment of acquired bilateral nevus of Ota-like macules (ABNOMs) in Koreans. (12243708)
2001
31
Scleral melanocytosis and oculodermal melanocytosis (nevus of Ota) in Chinese children. (11035844)
2000
32
An in vivo trial comparing the clinical efficacy and complications of Q-switched 755 nm alexandrite and Q-switched 1064 nm Nd:YAG lasers in the treatment of nevus of Ota. (11050493)
2000
33
Q-switched Nd:YAG laser treatment for acquired bilateral nevus of ota-like maculae: a long-term follow-up. (10805942)
2000
34
Treatment of nevus of Ota with the Candela PLDL and PLTL lasers. (8911487)
1996
35
Q-switched ruby laser treatment of oculodermal melanosis (nevus of Ota). (8823014)
1996
36
Treatment of nevus of Ota with the Q-switched ruby laser. (7984195)
1994
37
Nevus of Ota and leptomeningeal melanocytic lesions. (8437707)
1993
38
Q-switched ruby laser therapy of nevus of Ota. (1456756)
1992
39
Late-onset nevus of Ota. (1935251)
1991
40
Nevus of Ota with glaucoma: report of three cases. (1952636)
1991
41
Nevus of ota with nevus of Ito--report of a case with cataract. (2778194)
1989
42
Unusual presentations of Nevus of Ota. Case reports. (3842835)
1985
43
Dermal Merkel cells in the nevus of Ota and leopard syndrome. (6480925)
1984
44
Acquired, bilateral nevus of Ota-like macules. (6736340)
1984
45
Malignant melanoma of the choroid in the nevus of Ota of a black patient. (7138332)
1982
46
Electron microscopy. Ultrastructural observations of the extracellular sheath of dermal melanocytes in the nevus of Ota. (7114410)
1982
47
Malignant melanoma of choroid in a case of nevus of Ota. (434736)
1979
48
Malignant melanoma of the choroid in the nevus of Ota. (5369372)
1969
49
Malignant melanoma of the orbit arising in a nevus of Ota. (5970717)
1966
50
Cellular blue nevus of Ota followed for twenty-two years. (13325962)
1956

Variations for Nevus of Ota

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Expression for genes affiliated with Nevus of Ota

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Search GEO for disease gene expression data for Nevus of Ota.

Pathways for genes affiliated with Nevus of Ota

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GO Terms for genes affiliated with Nevus of Ota

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Biological processes related to Nevus of Ota according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cellular response to drugGO:00356909.1BRAF, TP53

Sources for Nevus of Ota

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet