MCID: NWB001
MIFTS: 41

Newborn Respiratory Distress Syndrome malady

Fetal diseases, Respiratory diseases categories
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Summaries for Newborn Respiratory Distress Syndrome

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8Disease Ontology, 47OMIM, 33MalaCards
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Disease Ontology:8 A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.

MalaCards: Newborn Respiratory Distress Syndrome, also known as respiratory distress syndrome, is related to pulmonary fibrosis and adult respiratory distress syndrome. An important gene associated with Newborn Respiratory Distress Syndrome is SFTPA1 (surfactant protein A1). The drugs albumin human, usp and albumin,human inj and the compounds proline and polyacrylamide have been mentioned in the context of this disorder. Affiliated tissues include lung and testes.

Description from OMIM:47 267450

Aliases & Classifications for Newborn Respiratory Distress Syndrome

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8Disease Ontology, 22GTR, 10DISEASES, 45Novoseek, 62UMLS, 58SNOMED-CT, 47OMIM, 35MeSH, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Respiratory diseases


Aliases & Descriptions:

newborn respiratory distress syndrome 8 10
respiratory distress syndrome 8 22 45 62
hyaline membrane disease 8 45 62
idiopathic respiratory distress syndrome irds 8
idiopathic respiratory distress syndrome, nos 8
respiratory distress syndrome in the newborn 8
pulmonary hypoperfusion syndrome of newborn 8
idiopathic respiratory distress of newborn 8
respiratory distress syndrome in newborn 8
respiratory distress syndrome of newborn 8
neonatal respiratory distress syndrome 8
respiratory distress syndrome, newborn 62
pulmonary hyaline membrane disease 8
hmd - hyaline membrane disease 8
rds of newborn 8


External Ids:

Disease Ontology8 DOID:12716
OMIM47 267450
MeSH35 D006819
ICD1025 P22, P22.0

Related Diseases for Newborn Respiratory Distress Syndrome

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Newborn Respiratory Distress Syndrome:



Diseases related to newborn respiratory distress syndrome

Symptoms for Newborn Respiratory Distress Syndrome

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47OMIM
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Clinical features from OMIM:

267450

Drugs & Therapeutics for Newborn Respiratory Distress Syndrome

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
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Drug clinical trials:

Search ClinicalTrials for Newborn Respiratory Distress Syndrome

Search NIH Clinical Center for Newborn Respiratory Distress Syndrome

Inferred drug relations via UMLS62/NDF-RT41:

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Genetic Tests for Newborn Respiratory Distress Syndrome

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22GTR
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Genetic tests related to Newborn Respiratory Distress Syndrome:

id Genetic test Affiliating Genes
1 Respiratory Distress22

Anatomical Context for Newborn Respiratory Distress Syndrome

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31LifeMap Discovery™, 33MalaCards
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MalaCards organs/tissues related to Newborn Respiratory Distress Syndrome:

33
Lung, Testes

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Newborn Respiratory Distress Syndrome:
id TissueAnatomical CompartmentCell Relevance
1 LungAlveoliAlveolar Epithelial Type 1 Cells Potential therapeutic candidate, affected by disease
2 LungAlveoliAlveolar Epithelial Type 2 Cells Potential therapeutic candidate, affected by disease
3 LungPulmonary Capillary Plexus  Affected by disease

Animal Models for Newborn Respiratory Distress Syndrome or affiliated genes

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Publications for Newborn Respiratory Distress Syndrome

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52PubMed
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Articles related to Newborn Respiratory Distress Syndrome:

idTitleAuthorsYear
1
Deficient Na+ channel expression in newborn respiratory distress syndrome. (15029631)
2004
2
Prediction of the newborn respiratory distress syndrome by means of the hydrogen peroxide hemolysis test. (6895985)
1982
3
The PaO2 response to changes in end expiratory pressure in the newborn respiratory distress syndrome. (332446)
1977

Variations for Newborn Respiratory Distress Syndrome

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Expression for genes affiliated with Newborn Respiratory Distress Syndrome

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Sources:
2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Newborn Respiratory Distress Syndrome

Search GEO for disease gene expression data for Newborn Respiratory Distress Syndrome.

Pathways for genes affiliated with Newborn Respiratory Distress Syndrome

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Compounds for genes affiliated with Newborn Respiratory Distress Syndrome

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45Novoseek, 29IUPHAR
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Compounds related to Newborn Respiratory Distress Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1proline459.3SERPINH1, TTN
2polyacrylamide459.0SERPINH1, TTN
3atp45 299.4CHPT1, SERPINH1, TTN

GO Terms for genes affiliated with Newborn Respiratory Distress Syndrome

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Products for genes affiliated with Newborn Respiratory Distress Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Newborn Respiratory Distress Syndrome

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet