MCID: NWB001
MIFTS: 36

Newborn Respiratory Distress Syndrome malady

Fetal diseases category

Summaries for Newborn Respiratory Distress Syndrome

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Disease Ontology:10 A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.

MalaCards based summary: Newborn Respiratory Distress Syndrome, also known as hyaline membrane disease, is related to interstitial emphysema and funisitis. An important gene associated with Newborn Respiratory Distress Syndrome is SFTPA1 (surfactant protein A1). The drugs nitric oxide and beractant and the compounds proline and polyacrylamide have been mentioned in the context of this disorder. Affiliated tissues include lung and testes.

Aliases & Classifications for Newborn Respiratory Distress Syndrome

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Newborn Respiratory Distress Syndrome, Aliases & Descriptions:

Name: Newborn Respiratory Distress Syndrome 32 10 12
Hyaline Membrane Disease 10 45 62
Pulmonary Hypoperfusion Syndrome of Newborn 10 62
Respiratory Distress Syndrome of Newborn 10 62
 
Pulmonary Hyaline Membrane Disease 10 62
Hmd - Hyaline Membrane Disease 10 62
Neonatal Respiratory Distress Syndrome 10
Respiratory Distress Syndrome, Newborn 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


External Ids:

Disease Ontology10 DOID:12716
MeSH35 D006819
ICD1027 P22, P22.0

Related Diseases for Newborn Respiratory Distress Syndrome

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Diseases related to Newborn Respiratory Distress Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial emphysema10.5
2funisitis10.4
3respiratory distress syndrome, infant10.4
4bronchopulmonary dysplasia10.3
5infant acute respiratory distress syndrome10.2
6preterm premature rupture of the membranes10.2
7pyruvate kinase deficiency10.2
8intrahepatic cholestasis10.2
9congenital hypothyroidism10.2
10cholestasis10.2
11hypothyroidism10.2
12chorioamnionitis10.1
13aspiration pneumonia10.1
14neonatal jaundice10.1
15pneumonia10.1
16pneumothorax10.1
17cor pulmonale10.1
18pulmonary fibrosis10.0SERPINH1

Graphical network of diseases related to Newborn Respiratory Distress Syndrome:



Diseases related to newborn respiratory distress syndrome

Symptoms for Newborn Respiratory Distress Syndrome

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Drugs & Therapeutics for Newborn Respiratory Distress Syndrome

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Drug clinical trials:

Search ClinicalTrials for Newborn Respiratory Distress Syndrome

Search NIH Clinical Center for Newborn Respiratory Distress Syndrome

Inferred drug relations via UMLS62/NDF-RT41:

Show with subtypes

Genetic Tests for Newborn Respiratory Distress Syndrome

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Anatomical Context for Newborn Respiratory Distress Syndrome

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MalaCards organs/tissues related to Newborn Respiratory Distress Syndrome:

33
Lung, Testes

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Newborn Respiratory Distress Syndrome:
id TissueAnatomical CompartmentCell Relevance
1 LungAlveoliAlveolar Epithelial Type 1 Cells Potential therapeutic candidate, affected by disease
2 LungAlveoliAlveolar Epithelial Type 2 Cells Potential therapeutic candidate, affected by disease
3 LungPulmonary Capillary Plexus  Affected by disease

Animal Models for Newborn Respiratory Distress Syndrome or affiliated genes

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Publications for Newborn Respiratory Distress Syndrome

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Articles related to Newborn Respiratory Distress Syndrome:

idTitleAuthorsYear
1
Deficient Na+ channel expression in newborn respiratory distress syndrome. (15029631)
2004
2
Prediction of the newborn respiratory distress syndrome by means of the hydrogen peroxide hemolysis test. (6895985)
1982
3
The PaO2 response to changes in end expiratory pressure in the newborn respiratory distress syndrome. (332446)
1977

Variations for Newborn Respiratory Distress Syndrome

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Expression for genes affiliated with Newborn Respiratory Distress Syndrome

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Search GEO for disease gene expression data for Newborn Respiratory Distress Syndrome.

Pathways for genes affiliated with Newborn Respiratory Distress Syndrome

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Compounds for genes affiliated with Newborn Respiratory Distress Syndrome

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Sources:
45Novoseek, 30IUPHAR
See all sources

Compounds related to Newborn Respiratory Distress Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1proline459.3SERPINH1, TTN
2polyacrylamide459.0SERPINH1, TTN
3atp45 309.4CHPT1, SERPINH1, TTN

GO Terms for genes affiliated with Newborn Respiratory Distress Syndrome

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Products for genes affiliated with Newborn Respiratory Distress Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Newborn Respiratory Distress Syndrome

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet