MCID: NWB001
MIFTS: 41

Newborn Respiratory Distress Syndrome malady

Fetal diseases, Respiratory diseases categories

Summaries for Newborn Respiratory Distress Syndrome

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9Disease Ontology, 48OMIM, 34MalaCards
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Disease Ontology:9 A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.

MalaCards: Newborn Respiratory Distress Syndrome, also known as respiratory distress syndrome, is related to pulmonary fibrosis and adult respiratory distress syndrome. An important gene associated with Newborn Respiratory Distress Syndrome is SFTPA1 (surfactant protein A1). The drugs albumin human, usp and albumin,human inj and the compounds proline and polyacrylamide have been mentioned in the context of this disorder. Affiliated tissues include lung and testes.

Description from OMIM:48 267450

Aliases & Classifications for Newborn Respiratory Distress Syndrome

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9Disease Ontology, 23GTR, 11DISEASES, 46Novoseek, 63UMLS, 59SNOMED-CT, 48OMIM, 36MeSH, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases
Anatomical: Respiratory diseases


Aliases & Descriptions:

newborn respiratory distress syndrome 9 11
respiratory distress syndrome 9 23 46 63
hyaline membrane disease 9 46 63
idiopathic respiratory distress syndrome irds 9
idiopathic respiratory distress syndrome, nos 9
respiratory distress syndrome in the newborn 9
pulmonary hypoperfusion syndrome of newborn 9
idiopathic respiratory distress of newborn 9
respiratory distress syndrome in newborn 9
respiratory distress syndrome of newborn 9
neonatal respiratory distress syndrome 9
respiratory distress syndrome, newborn 63
pulmonary hyaline membrane disease 9
hmd - hyaline membrane disease 9
rds of newborn 9


External Ids:

Disease Ontology9 DOID:12716
OMIM48 267450
MeSH36 D006819
ICD1026 P22, P22.0

Related Diseases for Newborn Respiratory Distress Syndrome

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Newborn Respiratory Distress Syndrome:



Diseases related to newborn respiratory distress syndrome

Symptoms for Newborn Respiratory Distress Syndrome

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48OMIM
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Clinical features from OMIM:

267450

Drugs & Therapeutics for Newborn Respiratory Distress Syndrome

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

Search CenterWatch for Newborn Respiratory Distress Syndrome

Drug clinical trials:

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Search NIH Clinical Center for Newborn Respiratory Distress Syndrome

Search CenterWatch for Newborn Respiratory Distress Syndrome

Inferred drug relations via UMLS63/NDF-RT42:

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Genetic Tests for Newborn Respiratory Distress Syndrome

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23GTR
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Genetic tests related to Newborn Respiratory Distress Syndrome:

id Genetic test Affiliating Genes
1 Respiratory Distress23

Anatomical Context for Newborn Respiratory Distress Syndrome

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32LifeMap Discoveryā„¢, 34MalaCards
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MalaCards organs/tissues related to Newborn Respiratory Distress Syndrome:

34
Lung, Testes

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Newborn Respiratory Distress Syndrome:
id TissueAnatomical CompartmentCell Relevance
1 LungAlveoliAlveolar Epithelial Type 1 Cells Potential therapeutic candidate, affected by disease
2 LungAlveoliAlveolar Epithelial Type 2 Cells Potential therapeutic candidate, affected by disease
3 LungPulmonary Capillary Plexus  Affected by disease

Animal Models for Newborn Respiratory Distress Syndrome or affiliated genes

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Publications for Newborn Respiratory Distress Syndrome

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53PubMed
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Articles related to Newborn Respiratory Distress Syndrome:

idTitleAuthorsYear
1
Deficient Na+ channel expression in newborn respiratory distress syndrome. (15029631)
2004
2
Prediction of the newborn respiratory distress syndrome by means of the hydrogen peroxide hemolysis test. (6895985)
1982
3
The PaO2 response to changes in end expiratory pressure in the newborn respiratory distress syndrome. (332446)
1977

Variations for Newborn Respiratory Distress Syndrome

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Expression for genes affiliated with Newborn Respiratory Distress Syndrome

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Newborn Respiratory Distress Syndrome

Search GEO for disease gene expression data for Newborn Respiratory Distress Syndrome.

Pathways for genes affiliated with Newborn Respiratory Distress Syndrome

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Compounds for genes affiliated with Newborn Respiratory Distress Syndrome

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Sources:
46Novoseek, 30IUPHAR
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Compounds related to Newborn Respiratory Distress Syndrome according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1proline469.3SERPINH1, TTN
2polyacrylamide469.0SERPINH1, TTN
3atp46 309.4CHPT1, SERPINH1, TTN

GO Terms for genes affiliated with Newborn Respiratory Distress Syndrome

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Products for genes affiliated with Newborn Respiratory Distress Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Newborn Respiratory Distress Syndrome

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet