MCID: NWB001
MIFTS: 32

Newborn Respiratory Distress Syndrome malady

Fetal diseases category

Summaries for Newborn Respiratory Distress Syndrome

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Disease Ontology:9 A respiratory failure that is characterized by deficiency of the surfactant coating the inner surface of the lungs, by failure of the lungs to expand and contract properly during breathing with resulting collapse, and by the accumulation of a protein-containing film lining the alveoli and their ducts.

MalaCards based summary: Newborn Respiratory Distress Syndrome, also known as hyaline membrane disease, is related to interstitial emphysema and funisitis. An important gene associated with Newborn Respiratory Distress Syndrome is SFTPA1 (surfactant protein A1). The drugs albumin human, usp and albumin,human inj and the compounds proline and polyacrylamide have been mentioned in the context of this disorder. Affiliated tissues include lung and testes.

Aliases & Classifications for Newborn Respiratory Distress Syndrome

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Newborn Respiratory Distress Syndrome, Aliases & Descriptions:

Name: Newborn Respiratory Distress Syndrome 30 9 11
Hyaline Membrane Disease 9 43 60
Pulmonary Hypoperfusion Syndrome of Newborn 9
Respiratory Distress Syndrome of Newborn 9
 
Neonatal Respiratory Distress Syndrome 9
Respiratory Distress Syndrome, Newborn 60
Pulmonary Hyaline Membrane Disease 9
Hmd - Hyaline Membrane Disease 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Fetal diseases


External Ids:

Disease Ontology9 DOID:12716
MeSH33 D006819
ICD1025 P22, P22.0

Related Diseases for Newborn Respiratory Distress Syndrome

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Diseases related to Newborn Respiratory Distress Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial emphysema10.5
2funisitis10.4
3bronchopulmonary dysplasia10.3
4pulmonary fibrosis10.2SERPINH1
5infant acute respiratory distress syndrome10.2
6preterm premature rupture of the membranes10.2
7pyruvate kinase deficiency10.2
8intrahepatic cholestasis10.2
9congenital hypothyroidism10.2
10cholestasis10.2
11hypothyroidism10.2
12respiratory distress syndrome, infant10.2
13chorioamnionitis10.1
14aspiration pneumonia10.1
15neonatal jaundice10.1
16pneumonia10.1
17pneumothorax10.1
18cor pulmonale10.1

Graphical network of diseases related to Newborn Respiratory Distress Syndrome:



Diseases related to newborn respiratory distress syndrome

Symptoms for Newborn Respiratory Distress Syndrome

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Drugs & Therapeutics for Newborn Respiratory Distress Syndrome

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Drug clinical trials:

Search ClinicalTrials for Newborn Respiratory Distress Syndrome

Search NIH Clinical Center for Newborn Respiratory Distress Syndrome

Inferred drug relations via UMLS60/NDF-RT39:

Show with subtypes

Genetic Tests for Newborn Respiratory Distress Syndrome

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Anatomical Context for Newborn Respiratory Distress Syndrome

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MalaCards organs/tissues related to Newborn Respiratory Distress Syndrome:

31
Lung, Testes

LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Newborn Respiratory Distress Syndrome:
id TissueAnatomical CompartmentCell Relevance
1 LungAlveoliAlveolar Epithelial Type 1 Cells Potential therapeutic candidate, affected by disease
2 LungAlveoliAlveolar Epithelial Type 2 Cells Potential therapeutic candidate, affected by disease
3 LungPulmonary Capillary Plexus  Affected by disease

Animal Models for Newborn Respiratory Distress Syndrome or affiliated genes

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Publications for Newborn Respiratory Distress Syndrome

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Articles related to Newborn Respiratory Distress Syndrome:

idTitleAuthorsYear
1
Deficient Na+ channel expression in newborn respiratory distress syndrome. (15029631)
2004
2
Prediction of the newborn respiratory distress syndrome by means of the hydrogen peroxide hemolysis test. (6895985)
1982
3
The PaO2 response to changes in end expiratory pressure in the newborn respiratory distress syndrome. (332446)
1977

Variations for Newborn Respiratory Distress Syndrome

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Expression for genes affiliated with Newborn Respiratory Distress Syndrome

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Search GEO for disease gene expression data for Newborn Respiratory Distress Syndrome.

Pathways for genes affiliated with Newborn Respiratory Distress Syndrome

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Compounds for genes affiliated with Newborn Respiratory Distress Syndrome

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Sources:
43Novoseek, 28IUPHAR
See all sources

Compounds related to Newborn Respiratory Distress Syndrome according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1proline439.3SERPINH1, TTN
2polyacrylamide439.0SERPINH1, TTN
3atp43 289.4CHPT1, SERPINH1, TTN

GO Terms for genes affiliated with Newborn Respiratory Distress Syndrome

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Products for genes affiliated with Newborn Respiratory Distress Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Newborn Respiratory Distress Syndrome

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet