MCID: NPP003
MIFTS: 16

Nipple Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Nipple Neoplasm

MalaCards integrated aliases for Nipple Neoplasm:

Name: Nipple Neoplasm 12 69
Nipple Carcinoma 12 69
Tumor of Nipple 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3003 DOID:6629
NCIt 47 C5212 C28432

Summaries for Nipple Neoplasm

Disease Ontology : 12 A breast carcinoma that is located in the nipple.

MalaCards based summary : Nipple Neoplasm, also known as nipple carcinoma, is related to nipple duct carcinoma. The drugs Medroxyprogesterone acetate and Tamoxifen have been mentioned in the context of this disorder. Affiliated tissues include breast, lymph node and testes.

Related Diseases for Nipple Neoplasm

Diseases related to Nipple Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

id Related Disease Score Top Affiliating Genes
1 nipple duct carcinoma 10.8

Symptoms & Phenotypes for Nipple Neoplasm

Drugs & Therapeutics for Nipple Neoplasm

Drugs for Nipple Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 60)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Medroxyprogesterone acetate Approved, Investigational Phase 3 71-58-9
2
Tamoxifen Approved Phase 3,Phase 2,Phase 1 10540-29-1 2733526
3
Oxaliplatin Approved, Investigational Phase 3 61825-94-3 5310940 9887054 43805 6857599
4
Pregabalin Approved, Illicit, Investigational Phase 3 148553-50-8 5486971
5 Antineoplastic Agents, Hormonal Phase 3,Phase 1
6 Bone Density Conservation Agents Phase 3,Phase 1
7 Contraceptive Agents Phase 3
8 Contraceptive Agents, Male Phase 3
9 Contraceptives, Oral Phase 3
10 Estrogen Antagonists Phase 3,Phase 1
11 Estrogen Receptor Modulators Phase 3,Phase 1
12 Estrogens Phase 3,Phase 2,Phase 1
13 Hormone Antagonists Phase 3,Phase 2,Phase 1
14 Hormones Phase 3,Phase 2,Phase 1
15 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2,Phase 1
16
Medroxyprogesterone Phase 3 520-85-4 10631
17 Selective Estrogen Receptor Modulators Phase 3,Phase 1
18 Analgesics Phase 3,Phase 1
19 Anti-Anxiety Agents Phase 3
20 Anticonvulsants Phase 3
21 calcium channel blockers Phase 3
22 Calcium, Dietary Phase 3
23 Central Nervous System Depressants Phase 3
24 Peripheral Nervous System Agents Phase 3,Phase 1
25 Psychotropic Drugs Phase 3
26 Tranquilizing Agents Phase 3
27 Omega 3 Fatty Acid Nutraceutical Phase 3
28 Citrate Nutraceutical Phase 3
29
Citric Acid Nutraceutical, Vet_approved Phase 3 77-92-9 311
30 Soy Bean Nutraceutical Phase 3
31
Genistein Investigational Phase 2 446-72-0 5280961
32 Phytoestrogens Phase 2
33 Protective Agents Phase 2
34 Protein Kinase Inhibitors Phase 2
35
Sulindac Approved Phase 1 38194-50-2 5352 1548887
36
Fenretinide Investigational Phase 1 65646-68-6
37 Analgesics, Non-Narcotic Phase 1
38 Anti-Inflammatory Agents Phase 1
39 Anti-Inflammatory Agents, Non-Steroidal Phase 1
40 Antirheumatic Agents Phase 1
41 Cyclooxygenase Inhibitors Phase 1
42 Retinamide Phase 1
43
Zinc Approved 7440-66-6 32051 23994
44
Anastrozole Approved, Investigational 120511-73-1 2187
45
Oxytocin Approved, Vet_approved Early Phase 1 50-56-6 439302 53477758
46
Glucosamine Approved, Nutraceutical 3416-24-8 439213
47 Radiopharmaceuticals
48 Technetium Tc 99m Sulfur Colloid
49 Anesthetics
50 Technetium Tc 99m Sestamibi

Interventional clinical trials:

(show top 50) (show all 62)

id Name Status NCT ID Phase Drugs
1 Breast Reconstruction With Acellular Dermal Matrix in the Setting of Breast Cancer Treatment Completed NCT02061527 Phase 4
2 Protexa® Versus TiLoopBra® in Immediate Breast Reconstruction- A Pilot Study Completed NCT02562170 Phase 4
3 Selective Lymph Node Dissection Using Fluorescent Dye in Node-positive Breast Cancer Recruiting NCT02781259 Phase 4 Indocyanine green
4 Effects of Omega-3 Fatty Acids on Risk Factors for Breast Cancer in Pre-menopausal Women Completed NCT02816125 Phase 3
5 S9630, Medroxyprogesterone in Treating Women With Breast Cancer Completed NCT00002920 Phase 3 medroxyprogesterone;tamoxifen citrate
6 Effect of Dietary Soy on Estrogens in Breast Fluid, Blood, and Urine Samples From Healthy Women Completed NCT00513916 Phase 3
7 SuPr Study (Supine Versus Prone Treatment Position in Breast Radiotherapy) Completed NCT01001728 Phase 3
8 Evaluate The Efficacy and Safety Of Pregabalin In Prevention, Reduction of Oxaliplatin-Induced Painful Neuropathy Completed NCT01450163 Phase 3 Pregabalin, Oxaliplatin;Placebo , Oxaliplatin
9 Therapeutic Nipple Sparing Mastectomy. Recruiting NCT02311959 Phase 3
10 A Trial of the ForeCYTE Breast Aspirator for Cytological Testing of Nipple Aspirate Fluid in Women 30-55 Years Old Withdrawn NCT02539615 Phase 3
11 Nipple Aspiration, Ductal Lavage, and Duct Endoscopy For Diagnostic Assessment in Women Undergoing Surgery for Breast Cancer Unknown status NCT00083018 Phase 2
12 Genistein in Preventing Breast Cancer in Women at High Risk for Breast Cancer Completed NCT00290758 Phase 2 placebo;genistein
13 Compare Outcomes Between Two Acellular Dermal Matrices Recruiting NCT02891759 Phase 2
14 Ductal Lavage in Assessing Women With Early Breast Cancer or at High Risk of Developing Breast Cancer and Who Are Eligible For Tamoxifen Therapy Withdrawn NCT00083044 Phase 2
15 Sulindac in Preventing Breast Cancer in Women at High Risk for Breast Cancer Completed NCT00245024 Phase 1 sulindac
16 A Pilot Trial of Tamoxifen and 4-HPR (4-N-Hydroxyphenyl Retinamide) in Persons at High Risk for Developing Breast Cancer Completed NCT00001378 Phase 1 fenretinide
17 Earlier Breast Cancer Detection Using Automated Whole Breast Ultrasound With Mammography, Including Cost Comparisons Unknown status NCT00649337
18 Biomarker Breast Pap Test Unknown status NCT01683305
19 Prospective Non-randomized Evaluation of Oncoplastic Surgery Unknown status NCT01396993
20 Medical Radiometer - RTM - 01 - RES and Its Use in Detecting Hotspots in Female Breast Unknown status NCT02286583
21 A Pilot Study to Evaluate Nipple-Areolar Complex (NAC) Sparing Mastectomy Completed NCT00539227
22 Nipple Aspiration, Ductal Lavage, and Duct Endoscopy in Screening Women at Moderate-to-High Risk of Developing Breast Cancer Completed NCT00081003
23 Protocol for Postmenopausal Women at Increased Risk of Developing Breast Cancer Completed NCT00291083
24 Injection Methods in Finding the Sentinel Lymph Node During Lymphatic Mapping and Sentinel Lymph Node Biopsy in Patients With Invasive Breast Cancer Completed NCT00438477 Isosulfan Blue
25 The Breast Duct: Pilot Study of Genomic Sequencing of Exfoliated Ductal Cells Obtained Through Endoscopy and Lavage Completed NCT02121873
26 ForeCYTE Breast Aspirator for Sample Collection and Cytological Testing of Nipple Aspirate Fluid Completed NCT02218385
27 Molecular Breast Imaging in Patients With a History of Bloody Nipple Discharge Completed NCT00566280
28 Nipple Areola Complex Conservation Completed NCT00641628
29 Evaluation of the Cook Biodesign® Nipple Reconstruction Cylinder (NRC) Completed NCT01216319
30 Study of Ductal Lavage in Women at High Risk for Breast Cancer Completed NCT00429988
31 Susceptibility to Breast Cancer Completed NCT00004565
32 Evaluation of Antiproliferative Effects of Arimidex in Ductal Lavage Fluid in Patients With Breast Cancer Completed NCT01207635
33 NAC Sparing Mastectomy After Neo-adjuvant Chemotherapy Completed NCT02471742
34 Technetium Tc 99m Sulfur Colloid and Blue Dye In Detecting Sentinel Lymph Nodes in Patients With Breast Cancer Completed NCT00052676 patent blue V dye
35 Study to Assess Perfusion and Patient Satisfaction in Nipple-Areola Mastectomy With Immediate Reconstruction Completed NCT01969448
36 Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-Up Study Completed NCT00006421
37 Nuclear Morphology of Breast Cells in Ductal Lavage Completed NCT00259597
38 Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Menstrual Cycle Study Completed NCT00006425
39 Intra-operative Radiotherapy For Breast Cancer Women After NSM Recruiting NCT02389686
40 Nipple-Areola Complex (NAC) Irradiation After Nipple-Sparing Mastectomy and Reconstruction Recruiting NCT01208974
41 Diagnostic Utility of MRI in Female Patients With Nipple Discharge: A Prospective Trial Recruiting NCT02818946
42 Pilot Study of Oxytocin and microRNA Identification in NAF, Serum, and Tissue in Women With Breast Cancer Recruiting NCT02127073 Early Phase 1 Intranasal Oxytocin
43 A Study to Evaluate the Use of Supine MRI Images in Breast Conserving Surgery Recruiting NCT01929395
44 Benefit of a Diagnostic MRI in Case of Pathological Nipple Discharge With Normal Mammography / Ultrasound Recruiting NCT02819362
45 Localization of Intercostal Perforating Vessels Reduces Wound Complications From Nipple Sparing Mastectomy Recruiting NCT02938390
46 Study to Assess Breast Sensation Before and After Breast Cancer Treatment Recruiting NCT02817607
47 Case Collection Study to Determine the Accuracy, Call Back and Cancer Detection Rates of QT Ultrasound in Breast Imaging Recruiting NCT03052166
48 Nipple Sparing Mastectomy - Cosmetic Outcomes Active, not recruiting NCT01002014
49 Studying Biomarkers in Nipple Fluid, Urine, and Blood Samples From Women With Newly Diagnosed Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer and in Women at Risk of Developing Breast Cancer Active, not recruiting NCT00897208
50 HylaCare in the Treatment of Acute Skin Changes in Patients Undergoing Radiotherapy for Breast Cancer Active, not recruiting NCT02165605 HylaCare;Placebo

Search NIH Clinical Center for Nipple Neoplasm

Genetic Tests for Nipple Neoplasm

Anatomical Context for Nipple Neoplasm

MalaCards organs/tissues related to Nipple Neoplasm:

39
Breast, Lymph Node, Testes, Bone, Skin

Publications for Nipple Neoplasm

Variations for Nipple Neoplasm

Expression for Nipple Neoplasm

Search GEO for disease gene expression data for Nipple Neoplasm.

Pathways for Nipple Neoplasm

GO Terms for Nipple Neoplasm

Sources for Nipple Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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