Nodular Lymphocyte Predominant Hodgkin Lymphoma disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Summaries for Nodular Lymphocyte Predominant Hodgkin Lymphoma

MalaCards based summary: Nodular Lymphocyte Predominant Hodgkin Lymphoma, also known as NLPHL, is related to diffuse large b-cell lymphoma and peripheral t-cell lymphoma, and has symptoms including lymphoma, lymphadenopathy and abnormality of immune system physiology. An important gene associated with Nodular Lymphocyte Predominant Hodgkin Lymphoma is PDCD1 (programmed cell death 1), and among its related pathways are Development Glucocorticoid receptor signaling and B Cell Receptor Signaling Pathway. The compounds cytidine and rituximab have been mentioned in the context of this disorder. Affiliated tissues include t cells, b cells and bone marrow, and related mouse phenotypes are growth/size/body and cellular.

Aliases & Classifications for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁴⁸Orphanet, ⁶¹UMLS, ²⁷ICD10 via Orphanet, ⁶²UMLS via Orphanet, ²⁶ICD10
See all sources

Nodular Lymphocyte Predominant Hodgkin Lymphoma, Aliases & Descriptions:

Name: Nodular Lymphocyte Predominant Hodgkin Lymphoma ⁴⁸ ⁶¹

Nlphl ⁴⁸ ⁶¹

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Blood diseases, Immune diseases

ICD10: ²⁷ ²⁶

Neoplasms

Malignant neoplasms, stated or presumed to be primary, of lymphoid, haematopoietic and related tissue

Hodgkin lymphoma

Nodular sclerosis classical Hodgkin lymphoma

Nodular lymphocyte predominant Hodgkin lymphoma

Orphanet: ⁴⁸

Rare haematological diseases

Rare tumors

Characteristics (Orphanet epidemiological data):

⁴⁸

nodular lymphocyte predominant hodgkin lymphoma:
Age of onset: Variable; Age of death: Any age

External Ids:

ICD10 via Orphanet²⁷ C81.1

UMLS via Orphanet⁶² C1334968, C2239290

ICD10²⁶ C81.0

Related Diseases for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
¹⁸GeneCards, ¹⁹GeneDecks
See all sources

Diseases related to Nodular Lymphocyte Predominant Hodgkin Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 28)

id	Related Disease	Score	Top Affiliating Genes
1	diffuse large b-cell lymphoma	31.8	MUM1
2	peripheral t-cell lymphoma	30.9	PAX5, BCL6
3	b-cell lymphomas	30.5	REL, PAX5, BCL6, SWAP70, POU2F2
4	t-cell/histiocyte rich large b cell lymphoma	10.8
5	hemolytic anemia	10.4
6	hepatitis	10.4
7	autoimmune hemolytic anemia	10.4
8	adult lymphoma	10.4
9	cervicitis	10.4
10	polyradiculopathy	10.4
11	sarcoma	10.4
12	lymphocyte-rich classical hodgkin lymphoma	10.4
13	angioimmunoblastic t-cell lymphoma	10.3	BCL6
14	central nervous system lymphoma	10.3	BCL6
15	central nervous system lymphoma, primary	10.1	PAX5, BCL6
16	lymphoblastic lymphoma	10.1	BCL6, PAX5
17	reticulosarcoma	10.0	PAX5, BCL6
18	anaplastic large cell lymphoma	10.0	BCL6, PAX5
19	burkitt's lymphoma	10.0	BCL6, PAX5
20	transitional cell carcinoma	9.9	PAX5, BCL6
21	follicular lymphoma	9.9	BCL6, PAX5, REL
22	plasmacytoma	9.9	PAX5, POU2F2, BCL6
23	viral infectious disease	9.8	BCL6, PDCD1, REL
24	non-hodgkin lymphoma	9.8	BCL6, PAX5, POU2F2
25	chronic lymphocytic leukemia	9.8	BCL6, PAX5
26	myeloma	9.8	BCL6, POU2F2, PAX5
27	ipex syndrome	9.4	BCL6, REL, PAX5, PDCD1, SWAP70
28	hodgkin's lymphoma	9.2	BCL6, REL, PAX5, POU2F2, POU2AF1, SWAP70

Graphical network of the top 20 diseases related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

Symptoms for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁵⁸The Human Phenotype Ontology, ⁴⁸Orphanet
See all sources

Symptoms:

⁴⁸ (show all 13)

lymphadenopathy/polyadenopathies
immunodeficiency/increased susceptibility to infections/recurrent infections
lymphoma
hyperhidrosis/increased sweating
pruritus/itching
hepatomegaly/liver enlargement (excluding storage disease)
splenomegaly

anorexia
bone marrow failure/pancytopenia
neoplasms/tumors
weight loss/loss of appetite/break in weight curve/general health alteration
fever/chilling
asthenia/fatigue/weakness

HPO human phenotypes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

(show all 11)

id	Description	Frequency	HPO Source Accession
1	lymphoma	hallmark (90%)	HP:0002665
2	lymphadenopathy	hallmark (90%)	HP:0002716
3	abnormality of immune system physiology	hallmark (90%)	HP:0010978
4	hyperhidrosis	occasional (7.5%)	HP:0000975
5	pruritus	occasional (7.5%)	HP:0000989
6	splenomegaly	occasional (7.5%)	HP:0001744
7	weight loss	occasional (7.5%)	HP:0001824
8	anorexia	occasional (7.5%)	HP:0002039
9	hepatomegaly	occasional (7.5%)	HP:0002240
10	abnormality of temperature regulation	occasional (7.5%)	HP:0004370
11	bone marrow hypocellularity	occasional (7.5%)	HP:0005528

Drugs & Therapeutics for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁴¹NIH Clinical Center, ⁶ClinicalTrials
See all sources

Drug clinical trials:

Search ClinicalTrials for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Search NIH Clinical Center for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Genetic Tests for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Anatomical Context for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
³²MalaCards
See all sources

MalaCards organs/tissues related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

³²

T cells, B cells, Bone marrow, Bone, Liver, Lymph node, Small intestine, Lung, Monocytes

Animal Models for Nodular Lymphocyte Predominant Hodgkin Lymphoma or affiliated genes

Sources:
³⁶MGI
See all sources

MGI Mouse Phenotypes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

³⁶

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	growth/size/body phenotype	MP:0005378	7.7	POU2AF1, BCL6, REL, PAX5, POU2F2
2	cellular phenotype	MP:0005384	7.4	POU2AF1, REL, BCL6, PDCD1, SWAP70, PAX5
3	mortality/aging	MP:0010768	7.1	POU2AF1, PDCD1, BCL6, REL, PAX5, POU2F2
4	hematopoietic system phenotype	MP:0005397	6.9	POU2AF1, SWAP70, PDCD1, BCL6, REL, PAX5
5	immune system phenotype	MP:0005387	6.9	SWAP70, REL, PAX5, POU2F2, POU2AF1, PDCD1

Publications for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁵¹PubMed
See all sources

Articles related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

(show top 50) (show all 89)

id	Title	Authors	Year
1	Nodular lymphocyte predominant hodgkin lymphoma: biology, diagnosis and treatment. (24650975)	Goel A.... Grossbard M.L.	2014
2	Performance of FDG PET/CT at initial diagnosis in a rare lymphoma: nodular lymphocyte-predominant Hodgkin lymphoma. (24965842)	Grellier J.F.... Brice P.	2014
3	Primary adrenal nodular lymphocyte-predominant Hodgkin lymphoma: A case report and review of the literature. (25120675)	Wang J.... She X.	2014
4	Intrafollicular classical Hodgkin lymphoma mimicking nodular lymphocyte predominant Hodgkin lymphoma: A report of two cases. (25394195)	Tatsuno M.... Kushima R.	2014
5	Nodular lymphocyte-predominant Hodgkin lymphoma in children: clinical course, biology, and management. (25296072)	Gorde-Grosjean S.... Landman-Parker J.	2014
6	EBV may be expressed in the LP cells of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) in both children and adults. (24525501)	Huppmann A.R.... Hasserjian R.P.	2014
7	Open questions in the management of nodular lymphocyte predominant hodgkin lymphoma. (24772357)	Tyran M.... Resbeut M.	2014
8	Fluorescence immunophenotyping and interphase cytogenetics (FICTION) detects BCL6 abnormalities, including gene amplification, in most cases of nodular lymphocyte-predominant Hodgkin lymphoma. (24678684)	Bakhirev A.G.... Czuchlewski D.R.	2014
9	The prognostic impact of variant histology in nodular lymphocyte-predominant Hodgkin lymphoma: a report from the German Hodgkin Study Group (GHSG). (24100447)	Hartmann S.... Klapper W.	2013
10	Treatment of nodular lymphocyte-predominant Hodgkin lymphoma-"do no harm". (24472810)	Bartlett N.L.	2013
11	High-dose chemotherapy and autologous stem cell transplantation for nodular lymphocyte-predominant Hodgkin lymphoma. (23507470)	Karuturi M.... Popat U.	2013
12	Nodular lymphocyte predominant hodgkin lymphoma and T cell/histiocyte rich large B cell lymphoma - endpoints of a spectrum of one disease? (24244368)	Hartmann S.... Hansmann M.L.	2013
13	Does functional imaging distinguish nodular lymphocyte-predominant hodgkin lymphoma from T-cell/histiocyte-rich large B-cell lymphoma? (23773450)	Barber N.A.... Bociek R.G.	2013
14	Complete response to brentuximab vedotin in a transplant-naA^ve patient with relapsed CD30-positive nodular lymphocyte-predominant Hodgkin lymphoma. (24472809)	O'Sullivan C.C.... Cheson B.D.	2013
15	Occurrence of nodular lymphocyte-predominant hodgkin lymphoma in hermansky-pudlak type 2 syndrome is associated to natural killer and natural killer T cell defects. (24302998)	Lorenzi L.... Parolini S.	2013
16	VII. Management of nodular lymphocyte-predominant Hodgkin lymphoma. (23775649)	Eichenauer D.A.... Engert A.	2013
17	High familial risk in nodular lymphocyte-predominant Hodgkin lymphoma. (23284040)	Saarinen S.... Aaltonen L.A.	2013
18	Does "in situ lymphoma" occur as a distinct step in the development of nodular lymphocyte-predominant Hodgkin lymphoma? (21732334)	Carbone A.	2012
19	The unique entity of nodular lymphocyte-predominant Hodgkin lymphoma: current approaches to diagnosis and management. (21812538)	Hawkes E.A.... Cunningham D.	2012
20	"Intrafollicular neoplasia" of nodular lymphocyte predominant Hodgkin lymphoma: description of a hypothetic early step of the disease. (22209342)	Carbone A.... Gloghini A.	2012
21	Peripheral blood lymphocyte/monocyte ratio at diagnosis and survival in nodular lymphocyte-predominant Hodgkin lymphoma. (22360654)	Porrata L.F.... Markovic S.N.	2012
22	Nodular lymphocyte-predominant hodgkin lymphoma with atypical T cells: a morphologic variant mimicking peripheral T-cell lymphoma. (21997687)	Sohani A.R.... Hasserjian R.P.	2011
23	Mycobacterium avium intracellulare infection coexistent with nodular lymphocyte predominant Hodgkin lymphoma involving the lung. (21399527)	Gupta S.... Warwick A.B.	2011
24	Coexisting and clonally identical classic hodgkin lymphoma and nodular lymphocyte predominant hodgkin lymphoma. (21490448)	Song J.Y.... Jaffe E.S.	2011
25	Nodular lymphocyte predominant Hodgkin lymphoma behaves as a distinct clinical entity with good outcome: evidence from 14-year follow-up in the West of Scotland Cancer Network. (21663507)	Farrell K.... Leach M.	2011
26	Analysis of KLHDC8B in familial nodular lymphocyte predominant Hodgkin lymphoma. (21517803)	Saarinen S.... AittomAoki K.	2011
27	Nodular, lymphocyte-predominant Hodgkin lymphoma: a long-term study and analysis of transformation to diffuse large B-cell lymphoma in a cohort of 164 patients from the Adult Lymphoma Study Group. (20029973)	Biasoli I.... Brice P.	2010
28	Programmed death 1 expression in variant immunoarchitectural patterns of nodular lymphocyte predominant Hodgkin lymphoma: comparison with CD57 and lymphomas in the differential diagnosis. (20825974)	Churchill H.R.... Natkunam Y.	2010
29	Nodular lymphocyte predominant Hodgkin lymphoma: diagnostic pearls and pitfalls. (20923296)	Smith L.B.	2010
30	Nodular lymphocyte-predominant Hodgkin lymphoma and T cell histiocyte-rich large B cell lymphoma: diagnosis in two monozygotic twins. (20653789)	Cano I.... Montes-Moreno S.	2010
31	Concurrent occurrence of nodular lymphocyte predominant Hodgkin lymphoma and Kaposi sarcoma in lymph nodes: a first case report. (20595178)	Zhan H.Q.... Li F.	2010
32	Nodular lymphocyte predominant Hodgkin lymphoma with clusters of LP Cells, acute inflammation, and fibrosis: a syncytial variant. (19730363)	Drakos E.... Medeiros L.J.	2009
33	The emerging role for rituximab in the treatment of nodular lymphocyte predominant Hodgkin lymphoma. (19606035)	Maeda L.S.... Advani R.H.	2009
34	Paraneoplastic lumbosacral axonal polyradiculopathy preceding the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma: a case report. (18720211)	Ingber S.... Buckstein R.	2008
35	Beyond the lymphocyte predominant cell: CD4+CD8+ T-cells in nodular lymphocyte predominant Hodgkin lymphoma. (18949610)	Rahemtullah A.... Hasserjian R.P.	2008
36	Refractory nodular lymphocyte predominant Hodgkin lymphoma transformed to T-cell/histiocyte-rich B-cell lymphoma in an adolescent: salvage therapy with allogeneic bone marrow transplantation. (19131792)	CouronnAc L.... Vannier J.P.	2008
37	Nodular lymphocyte-predominant Hodgkin lymphoma presenting as fulminant hepatic failure in a pediatric patient: a case report with pathologic, immunophenotypic, and molecular findings. (18227720)	Woolf K.M.... Warnke R.A.	2008
38	Nodular lymphocyte predominant Hodgkin lymphoma at atypical locations may be associated with increased numbers of large cells and a diffuse histologic component. (17918256)	Yang D.T.... Perkins S.L.	2008
39	Outcome of children with nodular lymphocyte predominant Hodgkin lymphoma - a Children's Cancer and Leukaemia Group report. (17760808)	Hall G.W.... Shankar A.	2007
40	Bilateral proptosis as the initial presentation of systemic nodular lymphocyte predominant Hodgkin lymphoma. (17613778)	Akoz A.G.... Ustun H.	2007
41	Anti-CD20 monoclonal antibody (rituximab) for therapy of CD20-positive nodular lymphocyte-predominant Hodgkin lymphoma in an 10-year-old girl. (17065142)	CuliA8 S.... Jankovic S.	2006
42	IgD positive L&H cells identify a unique subset of nodular lymphocyte predominant Hodgkin lymphoma. (16699312)	Prakash S.... Pittaluga S.	2006
43	A double-positive CD4+CD8+ T-cell population is commonly found in nodular lymphocyte predominant Hodgkin lymphoma. (17050078)	Rahemtullah A.... Hasserjian R.P.	2006
44	Familial nodular lymphocyte predominant Hodgkin lymphoma: Successful treatment with CHOP plus rituximab. (16236615)	Unal A.... Cetin M.	2005
45	Differential expression patterns of c-REL protein in classic and nodular lymphocyte predominant Hodgkin lymphoma. (15551733)	Xiao Q.... Teruya-Feldstein J.	2004
46	Nodular lymphocyte predominant Hodgkin lymphoma in siblings. (15160926)	Campbell G.N.... Bain B.J.	2004
47	Bone marrow involvement in patients with nodular lymphocyte predominant Hodgkin lymphoma. (15087668)	Khoury J.D.... Medeiros L.J.	2004
48	Diffuse large B-cell lymphoma arising in nodular lymphocyte predominant hodgkin lymphoma. A report of 21 cases from the Nebraska Lymphoma Study Group. (14738141)	Huang J.Z.... Armitage J.O.	2003
49	Characterization of variant patterns of nodular lymphocyte predominant hodgkin lymphoma with immunohistologic and clinical correlation. (14508396)	Fan Z.... Warnke R.A.	2003
50	Frequent occurrence of BCL6 rearrangements in nodular lymphocyte predominance Hodgkin lymphoma but not in classical Hodgkin lymphoma. (12393409)	Wlodarska I.... Hagemeijer A.	2003

Genes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
¹⁸GeneCards, ¹antibodies-online, ⁴⁵Novus Biologicals
See all sources

Genes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma:

- Elite gene

id	Symbol	Description	Score	Implication
1	PDCD1	programmed cell death 1	21.39	GeneCards inferred via : Publications (show sections)
2	REL	v-rel avian reticuloendotheliosis viral oncogene homolog	18.89	GeneCards inferred via : Publications (show sections)
3	PAX5	paired box 5	16.39	GeneCards inferred via : Publications (show sections)
4	MUM1	melanoma associated antigen (mutated) 1	13.89	GeneCards inferred via : Publications (show sections)
5	POU2AF1	POU class 2 associating factor 1	11.39	GeneCards inferred via : Publications (show sections)
6	POU2F2	POU class 2 homeobox 2	8.89	GeneCards inferred via : Publications (show sections)
7	BCL6	B-cell CLL/lymphoma 6	6.39	GeneCards inferred via : Publications (show sections)
8	SWAP70	SWAP switching B-cell complex 70kDa subunit	3.89	GeneCards inferred via : Publications (show sections)

Products for genes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma disease:

id	Company	Proteins	Lysates	Antibodies	Kits and Assays
1	Antibodies-online	8	-	8	8
2	Novus Biologicals	7	7	8	-

Variations for Nodular Lymphocyte Predominant Hodgkin Lymphoma

Expression for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
²BioGPS, ¹⁶Gene Expression Omnibus DataSets
See all sources

Expression patterns in normal tissues for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Search GEO for disease gene expression data for Nodular Lymphocyte Predominant Hodgkin Lymphoma.

Pathways for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁴⁹PathCards, ⁵⁹Thomson Reuters, ³⁷NCBI BioSystems Database, ⁵Cell Signaling Technology, ³⁰KEGG
See all sources

Pathways related to Nodular Lymphocyte Predominant Hodgkin Lymphoma according to GeneCards/GeneDecks:

id	Super pathways (with members indented)	Score	Top Affiliating Genes
1	Development Glucocorticoid receptor signaling⁵⁹	9.5	POU2F2, REL
2	B Cell Receptor Signaling Pathway³⁷	9.3	REL, BCL6
3	Lymphocyte Signaling⁵	9.2	BCL6, PAX5
4	B Cell Receptor Signaling Pathway³⁷ Show member pathways B cell receptor signaling pathway³⁰ BCR signaling pathway³⁷ TCR Signaling Pathway³⁷ T cell receptor signaling pathway³⁰	9.1	POU2F2, REL, PDCD1
5	Transcriptional misregulation in cancer³⁰	8.9	PAX5, REL, BCL6

Compounds for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
⁴⁴Novoseek, ²⁵HMDB, ¹²DrugBank, ⁵⁰PharmGKB
See all sources

Compounds related to Nodular Lymphocyte Predominant Hodgkin Lymphoma according to GeneCards/GeneDecks:

id	Compound	Score	Top Affiliating Genes
1	cytidine⁴⁴ ²⁵ ¹²	11.3	PAX5, BCL6
2	rituximab⁴⁴ ⁵⁰ ¹²	11.2	BCL6, PAX5
3	zinc⁴⁴ ²⁵	9.9	BCL6, REL, PAX5
4	oligonucleotide⁴⁴	8.8	POU2F2, PAX5, REL
5	serine⁴⁴	8.1	REL, BCL6, POU2F2, PAX5
6	tyrosine⁴⁴	7.0	SWAP70, POU2AF1, POU2F2, PAX5, REL, BCL6

GO Terms for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Sources:
¹⁷Gene Ontology
See all sources

Cellular components related to Nodular Lymphocyte Predominant Hodgkin Lymphoma according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	nucleus	GO:005634	7.1	SWAP70, BCL6, MUM1, PAX5, POU2F2, POU2AF1

Biological processes related to Nodular Lymphocyte Predominant Hodgkin Lymphoma according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	transcription from RNA polymerase II promoter	GO:006366	8.9	PAX5, POU2F2, POU2AF1
2	humoral immune response	GO:006959	8.3	PDCD1, PAX5, POU2F2, POU2AF1

Molecular functions related to Nodular Lymphocyte Predominant Hodgkin Lymphoma according to GeneCards/GeneDecks:

id	Name	GO ID	Score	Top Affiliating Genes
1	sequence-specific DNA binding	GO:043565	8.7	BCL6, REL, POU2F2
2	sequence-specific DNA binding transcription factor activity	GO:003700	7.9	BCL6, REL, PAX5, POU2F2

Products for genes affiliated with Nodular Lymphocyte Predominant Hodgkin Lymphoma

Antibodies
Proteins
Lysates

Antibodies
Proteins
Kits and Assays

Sources for Nodular Lymphocyte Predominant Hodgkin Lymphoma

¹antibodies-online

²BioGPS

³BitterDB

⁴CDC

⁵Cell Signaling Technology

⁶ClinicalTrials

⁷Clinvar

⁸dbSNP

⁹Disease Ontology

¹⁰diseasecard

¹¹DISEASES

¹²DrugBank

¹³EMD Millipore

¹⁴ExPASy

¹⁵FMA

¹⁶Gene Expression Omnibus DataSets

¹⁷Gene Ontology

¹⁸GeneCards

¹⁹GeneDecks

²⁰GeneReviews

²¹GeneTests

²²Genetics Home Reference

²³GTR

²⁴HGMD

²⁵HMDB

²⁶ICD10

²⁷ICD10 via Orphanet

²⁸ICD9CM

²⁹IUPHAR

³⁰KEGG

³¹LifeMap Discovery®

³²MalaCards

³³MedlinePlus

³⁴MeSH

³⁵MESH via Orphanet

³⁶MGI

³⁷NCBI BioSystems Database

³⁸NCBI Bookshelf

³⁹NCIt

⁴⁰NDF-RT

⁴¹NIH Clinical Center

⁴²NIH Rare Diseases

⁴³NINDS

⁴⁴Novoseek

⁴⁵Novus Biologicals

⁴⁶OMIM

⁴⁷OMIM via Orphanet

⁴⁸Orphanet

⁴⁹PathCards

⁵⁰PharmGKB

⁵¹PubMed

⁵²QIAGEN

⁵³R&D Systems

⁵⁴Reactome

⁵⁵SinoBiological

⁵⁶SNOMED-CT

⁵⁷SNOMED-CT via Orphanet

⁵⁸The Human Phenotype Ontology

⁵⁹Thomson Reuters

⁶⁰Tocris Bioscience

⁶¹UMLS

⁶²UMLS via Orphanet

⁶³UniProtKB/Swiss-Prot

⁶⁴Wikipedia

Nodular Lymphocyte Predominant Hodgkin Lymphoma (NLPHL) malady