MCID: NNH002
MIFTS: 23

Non-a-E Hepatitis malady

Summaries for Non-a-E Hepatitis

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Sources:
42NIH Rare Diseases, 32MalaCards
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NIH Rare Diseases:42 Non-a-e hepatitis, sometimes referred to as hepatitis x, is a disease of the liver that is diagnosed when there is swelling of the liver (hepatitis) but examination and testing does not identify a cause.  symptoms of non-a-e hepatitis may include feeling tired or unwell (malaise), nausea, vomiting, pain in the abdomen, and fever.  non-a-e hepatitis usually goes away on its own, but it can become a chronic condition in a small proportion (12%) of affected individuals.  the cause of non-a-e hepatitis is currently unknown. last updated: 8/16/2012

MalaCards: Non-a-E Hepatitis, also known as viral hepatitis non-a,-b,-c,-d,-e, is related to hepatitis a and hepatitis e. An important gene associated with Non-a-E Hepatitis is AMACR (alpha-methylacyl-CoA racemase). The compounds monoethylglycinexylidide and ximelagatran have been mentioned in the context of this disorder. Affiliated tissues include liver and testes.

Aliases & Classifications for Non-a-E Hepatitis

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42NIH Rare Diseases
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Aliases & Descriptions:

non-a-e hepatitis 42
viral hepatitis non-a,-b,-c,-d,-e 42
hepatitis x 42


Related Diseases for Non-a-E Hepatitis

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Non-a-E Hepatitis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 56)
idRelated DiseaseScoreTop Affiliating Genes
1hepatitis a31.2F2
2hepatitis e31.2GPT
3hepatitis31.1SLC17A5, F2, GPT, AMACR
4hepatitis c30.7SLC17A5, F2, GPT, AMACR
5hepatitis b30.5SLC17A5, F2, GPT
6acute liver failure30.1SLC17A5, F2, GPT
7viral hepatitis30.1SLC17A5, F2, GPT
8aplastic anemia10.1
9biliary tract disease10.1
10cystic fibrosis10.0AMACR
11galactosemia10.0F2
12thromboembolism10.0F2
13cholelithiasis10.0GPT
14tuberculosis10.0AMACR
15biliary atresia10.0GPT
16myelodysplastic syndromes10.0AMACR
17stomach cancer10.0AMACR
18melanoma10.0AMACR
19lipoma10.0AMACR
20peritonitis10.0F2
21cholecystitis10.0GPT
22cryoglobulinemia10.0SLC17A5
23disseminated intravascular coagulation10.0F2
24hyperthyroidism10.0SLC17A5
25prostate cancer10.0AMACR
26glucose intolerance10.0GPT
27pancreatitis10.0SLC17A5
28ischemia10.0SLC17A5
29hellp syndrome10.0SLC17A5, GPT
30pyridoxine deficiency10.0SLC17A5, GPT
31wilson disease10.0GPT, SLC17A5
32cholangitis10.0SLC17A5, GPT
33obstructive jaundice10.0GPT, SLC17A5
34acute pancreatitis10.0SLC17A5, GPT
35hypercholesterolemia10.0SLC17A5, GPT
36choledocholithiasis10.0GPT, SLC17A5
37scrub typhus10.0SLC17A5, GPT
38congenital stationary night blindness, type 1f10.0GPT, SLC17A5
39splenomegaly10.0SLC17A5, GPT
40alcohol abuse10.0GPT, SLC17A5
41familial hyperlipidemia10.0GPT, SLC17A5
42fatty liver disease10.0SLC17A5, GPT
43factor v leiden thrombophilia10.0AMACR, F2, SLC17A5
44alcoholic hepatitis10.0GPT, F2, SLC17A5
45bilirubin metabolic disorder10.0GPT, F2, SLC17A5
46portal hypertension10.0GPT, F2, SLC17A5
47cholestasis10.0GPT, F2, SLC17A5
48alcoholic liver cirrhosis10.0SLC17A5, F2, GPT
49hepatic encephalopathy10.0GPT, F2, SLC17A5
50autoimmune hepatitis10.0GPT, F2, SLC17A5

Graphical network of the top 20 diseases related to Non-a-E Hepatitis:



Diseases related to non-a-e hepatitis

Clinical Features for Non-a-E Hepatitis

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Drugs & Therapeutics for Non-a-E Hepatitis

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Non-a-E Hepatitis

Drug clinical trials:

Search ClinicalTrials for Non-a-E Hepatitis

Search NIH Clinical Center for Non-a-E Hepatitis

Search CenterWatch for Non-a-E Hepatitis

Genetic Tests for Non-a-E Hepatitis

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Anatomical Context for Non-a-E Hepatitis

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Sources:
32MalaCards
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MalaCards organs/tissues related to Non-a-E Hepatitis:

32
Liver, Testes

Animal Models for Non-a-E Hepatitis or affiliated genes

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Publications for Non-a-E Hepatitis

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Genetic Variations for Non-a-E Hepatitis

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Expression for genes affiliated with Non-a-E Hepatitis

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Non-a-E Hepatitis

Search GEO for disease gene expression data for Non-a-E Hepatitis.

Pathways for genes affiliated with Non-a-E Hepatitis

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Compounds for genes affiliated with Non-a-E Hepatitis

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Sources:
44Novoseek, 11DrugBank, 59Tocris Bioscience, 28IUPHAR, 49PharmGKB, 24HMDB, 2BitterDB
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Compounds related to Non-a-E Hepatitis according to GeneCards/GeneDecks:

(show top 50)    (show all 75)
idCompoundScoreTop Affiliating Genes
1monoethylglycinexylidide449.8GPT, F2
2ximelagatran44 1110.8F2, GPT
3clarithromycin44 1110.7GPT, F2
4lamivudine44 1110.6SLC17A5, F2
5antipyrine44 1110.5SLC17A5, F2
6levonorgestrel44 59 28 1112.5SLC17A5, F2
7amiodarone44 49 28 1112.5F2, SLC17A5
85-hydroxytryptophol449.5GPT, SLC17A5
9alpha-hydroxybutyrate449.5SLC17A5, GPT
10d-galactosamine449.5SLC17A5, GPT
11lactulose449.4GPT, SLC17A5
12adefovir449.4GPT, SLC17A5
13glycocholate449.4GPT, SLC17A5
14tenofovir44 49 1111.4GPT, SLC17A5
15glycyrrhizin44 2810.4GPT, SLC17A5
16nash449.4SLC17A5, GPT
17lidocaine44 28 1111.4SLC17A5, F2
18nevirapine44 49 1111.4SLC17A5, GPT
19sevoflurane44 1110.4SLC17A5, GPT
20isoniazid49 44 1111.4SLC17A5, GPT
21digoxin44 49 59 11 2413.4F2, SLC17A5
22isoflurane44 1110.4SLC17A5, GPT
23ezetimibe44 1110.4SLC17A5, GPT
24flutamide44 59 1111.3SLC17A5, GPT
25rosuvastatin44 49 28 1112.3SLC17A5, GPT
26disulfiram44 59 1111.3GPT, SLC17A5
27bezafibrate44 28 1111.3GPT, SLC17A5
28phosphorus449.2SLC17A5, GPT
29risperidone28 44 49 59 11 2414.2GPT, SLC17A5
30valproate449.1GPT, SLC17A5
31pyridoxal 5-phosphate449.0SLC17A5, GPT
32rifampicin44 28 5911.0SLC17A5, GPT
33hepaplastin449.0F2, GPT, SLC17A5
34aminopyrine449.0F2, GPT, SLC17A5
35ursodeoxycholic acid44 11 2411.0F2, SLC17A5, GPT
36silymarin449.0F2, GPT, SLC17A5
37acetaminophen44 2 49 11 2412.9SLC17A5, F2, GPT
38pge1448.9GPT, F2, SLC17A5
39fenofibrate44 49 1110.9GPT, SLC17A5
40simvastatin44 49 59 28 11 2413.9F2, SLC17A5, GPT
41hyaluronic acid44 249.9GPT, SLC17A5, F2
42chloride448.9AMACR, SLC17A5, GPT
43methotrexate44 49 1110.9GPT, SLC17A5, F2
44n acetylcysteine448.9SLC17A5, F2, GPT
45fibrinogen448.9GPT, SLC17A5, F2
46cyclosporin a44 28 5910.8GPT, F2, SLC17A5
47lactate448.8GPT, F2, SLC17A5
48ribavirin44 49 1110.7GPT, SLC17A5
49creatinine448.7GPT, F2, SLC17A5
50aspartate448.6GPT, F2, SLC17A5

GO Terms for genes affiliated with Non-a-E Hepatitis

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Products for genes affiliated with Non-a-E Hepatitis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Non-a-E Hepatitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet