MCID: NNH001
MIFTS: 73

Non-Hodgkin Lymphoma malady

Genetic diseases (common), Cancer diseases, Immune diseases categories
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Summaries for Non-Hodgkin Lymphoma

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Disease Ontology:8 A lymphoma that is characterized as any kind of lymphoma except hodgkin's lymphoma.

MalaCards based summary: Non-Hodgkin Lymphoma, also known as lymphoma, non-hodgkin, is related to chronic lymphocytic leukemia and mantle cell lymphoma. An important gene associated with Non-Hodgkin Lymphoma is PRF1 (perforin 1 (pore forming protein)), and among its related pathways are Thyroid cancer and BARD1 signaling events. The drugs mercaptopurine and carmustine and the compounds n-acetoxy-2-acetylaminofluorene and adozelesin have been mentioned in the context of this disorder. Affiliated tissues include b cells, t cells and bone, and related mouse phenotypes are tumorigenesis and craniofacial.

Description from OMIM:46 605027

Aliases & Classifications for Non-Hodgkin Lymphoma

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Non-Hodgkin Lymphoma, Aliases & Descriptions:

Name: Non-Hodgkin Lymphoma 30 8
Lymphoma, Non-Hodgkin 9 46 62
 
Lymphoma Non-Hodgkins 44


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Genetic diseases (common), Cancer diseases
Anatomical: Immune diseases


External Ids:

Disease Ontology8 DOID:0060060
OMIM46 605027
ICD1025 C85.7

Related Diseases for Non-Hodgkin Lymphoma

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Diseases related to Non-Hodgkin Lymphoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 262)
idRelated DiseaseScoreTop Affiliating Genes
1chronic lymphocytic leukemia31.9MS4A1, IGH
2mantle cell lymphoma31.8BCL6, MDM2
3leukemia31.6NBN, MDM2, CSF3, CASP10, BCL6, HPRT1
4myeloma31.6CSF3, BCL6, IGH
5acute lymphoblastic leukemia31.5IGH, NBN, HPRT1, BCL6, CSF3
6familial non-hodgkin lymphoma31.4CASP10, BRAF
7burkitt's lymphoma31.4MDM2, MS4A1, IGH, BCL6
8follicular lymphoma31.3IGH, MS4A1, BCL6
9multiple myeloma31.3TP53, CSF3
10lymphoblastic lymphoma31.1BCL6, MS4A1
11hodgkin's lymphoma30.9MS4A1, BCL6, CSF3, IGH, MDM2
12ataxia telangiectasia30.8NBN, MDM2, HPRT1, TP53
13colorectal cancer30.8HPRT1, BRAF, TP53, MDM2, NBN
14breast cancer30.7NBN, CASP10, TP53, MDM2, HPRT1
15lung cancer30.5NBN, BRAF, HPRT1, CSF3, MDM2, TP53
16lymphoma, non-hodgkin, somatic30.5RAD54L, RAD54B
17b-cell lymphomas30.3IGH, MS4A1, BCL6, TP53, NBN, PRF1
18breast ductal carcinoma30.3TP53, BCL6
19melanoma30.0BRAF, PRF1, MDM2, CASP10, HPRT1, TP53
20hepatitis10.8
21hepatitis c10.7
22spitz nevus10.6BRAF
23hematopoietic stem cell transplantation10.6
24hepatitis b10.6
25lymphoblastic leukemia10.5
26gastric lymphoma10.5IGH, BCL6
27aplastic anemia10.5CSF3, HPRT1, NBN
28developmental disabilities10.5RMRP, HPRT1, BRAF
29lymphosarcoma10.5BCL6, IGH
30acute lymphoblastic leukemia, childhood10.5IGH, NBN, HPRT1, MDM2
31neutropenia10.5
32cryoglobulinemia10.5
33progressive multifocal leukoencephalopathy10.5
34pneumonia10.5
35sarcoma10.5
36macroglobulinemia, waldenstrom, somatic10.5IGH, MS4A1
37giant cell glioblastoma10.5MDM2
38hemolytic anemia10.4
39acquired immunodeficiency syndrome10.4
40autoimmune hemolytic anemia10.4
41obstructive jaundice10.4
42hairy cell leukemia10.4
43hepatitis c virus10.4
44endotheliitis10.4
45acute leukemia10.4
46renal cell carcinoma10.4
47kaposi's sarcoma10.4
48histiocytosis10.4
49meningitis10.4
50prostatitis10.4

Graphical network of the top 20 diseases related to Non-Hodgkin Lymphoma:



Diseases related to non-hodgkin lymphoma

Symptoms for Non-Hodgkin Lymphoma

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Clinical features from OMIM:

605027

Drugs & Therapeutics for Non-Hodgkin Lymphoma

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Genetic Tests for Non-Hodgkin Lymphoma

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Anatomical Context for Non-Hodgkin Lymphoma

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MalaCards organs/tissues related to Non-Hodgkin Lymphoma:

32
B cells, T cells, Bone, Bone marrow, Breast, Myeloid, Monocytes, Endothelial, Spinal cord, Heart, Liver, Skin, Prostate, Brain, Thyroid, Lymph node, Kidney, Lung, Testes, Nk cells, B lymphoblasts, Tongue, Pituitary, Neutrophil

LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine

Cells/anatomical compartments in embryo or adult related to Non-Hodgkin Lymphoma:
id TissueAnatomical CompartmentCell Relevance
1 BloodHematopoietic Bone MarrowHematopoietic Stem Cells Potential therapeutic candidate
2 BloodPeripheral BloodMature B-Cells Potential therapeutic candidate, affected by disease

Animal Models for Non-Hodgkin Lymphoma or affiliated genes

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MGI Mouse Phenotypes related to Non-Hodgkin Lymphoma:

36 (show all 11)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000200610.2NBN, MDM2, HPRT1, PRF1, BRAF, TP53
2MP:000538210.1BRAF, HPRT1, TP53, NBN, MDM2
3MP:000118610.1MDM2, HPRT1, BRAF, TP53
4MP:000537010.0BCL6, HPRT1, PRF1, TP53, MDM2, BRAF
5MP:00028739.9BRAF, PRF1, HPRT1, RMRP, BCL6, TP53
6MP:00053899.9HPRT1, PRF1, BRAF, TP53, NBN, MDM2
7MP:00053849.9NBN, MDM2, RAD54L, RAD54B, HPRT1, PRF1
8MP:00053879.8MDM2, RAD54L, CSF3, MS4A1, BCL6, HPRT1
9MP:00053979.8CSF3, MDM2, RAD54L, RAD54B, BCL6, HPRT1
10MP:00107689.8MDM2, BRAF, TP53, NBN, BCL6, RAD54L
11MP:00107719.7PRF1, HPRT1, TP53, CSF3, MDM2, BRAF

Publications for Non-Hodgkin Lymphoma

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Articles related to Non-Hodgkin Lymphoma:

(show top 50)    (show all 948)
idTitleAuthorsYear
1
Dietary patterns and the risk of non-Hodgkin lymphoma. (23659580)
2013
2
Primary non-Hodgkin lymphoma of the bladder. (24369199)
2013
3
Atrazine and nitrate in public drinking water supplies and non-hodgkin lymphoma in nebraska, USA. (23515852)
2013
4
Biodistribution and dosimetry of (177)Lu-tetulomab, a new radioimmunoconjugate for treatment of non-Hodgkin lymphoma. (23256748)
2013
5
Unusual hairy cell projections in hepatosplenic T-cell non-Hodgkin lymphoma. (23593648)
2013
6
External validation of a risk model of febrile neutropenia occurrence in patients with non-Hodgkin lymphoma. (23452152)
2013
7
Non-Hodgkin lymphoma as an uncommon cause of acute heart failure. (23503834)
2013
8
Phase I study of MLN8237-investigational Aurora A kinase inhibitor-in relapsed/refractory multiple myeloma, Non-Hodgkin lymphoma and chronic lymphocytic leukemia. (24352795)
2013
9
Long-Term Results of Autologous Hematopoietic Stem-Cell Transplantation After High-Dose 90Y-Ibritumomab Tiuxetan for Patients With Poor-Risk Non-Hodgkin Lymphoma Not Eligible for High-Dose BEAM. (23857974)
2013
10
Front-line immunochemotherapy for aggressive non-Hodgkin lymphoma using dose-dense rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone plus granulocyte-macrophage colony stimulating factor and pegfilgrastim as support. (22448918)
2012
11
Analysis of very elderly (a8Y80 years) non-hodgkin lymphoma: impact of functional status and co-morbidities on outcome. (22084970)
2012
12
The association of hepatitis B virus infection with B-cell non-Hodgkin lymphoma - a review. (22432084)
2012
13
Treatment option of bendamustine in combination with rituximab in elderly and frail patients with aggressive B-non-Hodgkin lymphoma: rational, efficacy, and tolerance. (22752146)
2012
14
Assessment of immunovirological features in HIV related non-Hodgkin lymphoma patients and their impact on outcome. (22244256)
2012
15
Cigarette smoking is associated with a small increase in the incidence of non-Hodgkin lymphoma: a meta-analysis of 24 observational studies. (22397720)
2012
16
Radiotherapy in stage I-III follicular non-Hodgkin lymphoma. Retrospective analysis of a series of 50 patients. (22349634)
2012
17
Long-term remission of paroxysmal nocturnal hemoglobinuria following chemoimmunotherapy for non-Hodgkin lymphoma. (22402359)
2012
18
Results of the Japan Association of Childhood Leukemia Study (JACLS) NHL-98 protocol for the treatment of B-cell non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia in childhood. (21261497)
2011
19
Expression of serine 194-phosphorylated Fas-associated death domain protein correlates with proliferation in B-cell non-Hodgkin lymphomas. (21315423)
2011
20
Non-hodgkin lymphoma in a child with schimke immuno-osseous dysplasia. (23359635)
2011
21
Soluble IL-2RI+ facilitates IL-2-mediated immune responses and predicts reduced survival in follicular B-cell non-Hodgkin lymphoma. (21719603)
2011
22
Sexual well-being among survivors of non-Hodgkin lymphoma. (21875831)
2011
23
KLF4 is a tumor suppressor in B-cell non-Hodgkin lymphoma and in classic Hodgkin lymphoma. (20519630)
2010
24
Association analysis between the Cdc6 G1321A polymorphism and the risk for non-Hodgkin lymphoma and hepatocellular carcinoma. (19101572)
2009
25
Organochlorine exposure, immune gene variation, and risk of non-Hodgkin lymphoma. (19066394)
2009
26
Functional signatures identified in B-cell non-Hodgkin lymphoma profiles. (19863341)
2009
27
A 19-year follow-up of a patient with type 3 ectrodactyly-ectodermal dysplasia-clefting syndrome who developed non-Hodgkin lymphoma. (19716498)
2009
28
Interleukine-2 therapy does not increase the risk of Hodgkin or non-Hodgkin lymphoma in HIV-infected patients: results from FHDH ANRS CO4. (19131886)
2009
29
Non-Hodgkin lymphoma (NHL) in children with Nijmegen Breakage syndrome (NBS). (18937313)
2009
30
Fatal chylous ascites, pericarditis and extensive venous thrombosis, due to an aggressive T cell non-Hodgkin lymphoma. (18679682)
2009
31
Genetic variation in B-cell-activating factor is associated with an increased risk of developing B-cell non-Hodgkin lymphoma. (19383901)
2009
32
Genetic variation in caspase genes and risk of non-Hodgkin lymphoma: a pooled analysis of 3 population-based case-control studies. (19414860)
2009
33
The NF-kappaB inhibitors (bortezomib and DHMEQ) sensitise rituximab-resistant AIDS-B-non-Hodgkin lymphoma to apoptosis by various chemotherapeutic drugs. (18949621)
2008
34
Non-Hodgkin lymphoma related to hereditary nonpolyposis colorectal cancer in a patient with a novel heterozygous complex deletion in the MSH2 gene. (18181177)
2008
35
Soft tissue non-Hodgkin lymphoma of shoulder in a HIV patient: a report of a case and review of the literature. (18939988)
2008
36
The use of galiximab in non-Hodgkin lymphoma. (18854281)
2008
37
Genetic polymorphisms in the proximal IL-10 promoter and susceptibility to non-Hodgkin lymphoma. (17990180)
2007
38
Polymorphisms in innate immunity genes and risk of non-Hodgkin lymphoma. (16740140)
2006
39
Polymorphisms in DNA repair genes and risk of non-Hodgkin lymphoma among women in Connecticut. (16738949)
2006
40
Risk of non-Hodgkin lymphoma (NHL) in relation to germline variation in DNA repair and related genes. (16857995)
2006
41
Inhibitory effect of triptolide on lymph node metastasis in patients with non-Hodgkin lymphoma by regulating SDF-1/CXCR4 axis in vitro. (17049119)
2006
42
A putative exonic splicing polymorphism in the BCL6 gene and the risk of non-Hodgkin lymphoma. (16264183)
2005
43
Alteration of SMRT tumor suppressor function in transformed non-Hodgkin lymphomas. (15930272)
2005
44
Intensive sequential chemotherapy with hematopoietic growth factor support for non-Hodgkin lymphoma in patients infected with the human immunodeficiency virus. (14770420)
2004
45
Expression profile and prognostic significance of CD24, p53 and p21 in lymphomas. A tissue microarray study of over 600 non-Hodgkin lymphomas]. (15455300)
2004
46
Antibody-targeted therapy: a paradigm of innovative treatment strategies in indolent and aggressive B-cell non-Hodgkin lymphoma. (15548997)
2004
47
Genotyping of AR and PSA polymorphisms in a patient with Klinefelter syndrome, non-Hodgkin lymphoma, and adenocarcinoma of the prostate. (15350307)
2004
48
Therapy-related acute leukemia associated with involvement of 11q23 after high grade non-Hodgkin lymphoma. (9573684)
1998
49
Chemosensitive epidural spinal cord disease in non-Hodgkins lymphoma. (8649545)
1996
50
Immunohistochemistry of Hodgkin and non-Hodgkin lymphomas with emphasis on the diagnostic significance of the BNH9 antibody reactivity with anaplastic large cell (CD30 positive) lymphomas. (1330287)
1992

Variations for Non-Hodgkin Lymphoma

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UniProtKB/Swiss-Prot genetic disease variations for Non-Hodgkin Lymphoma:

64
id Symbol AA change Variation ID SNP ID
1BRAFp.Gly469AlaVAR_018620
2BRAFp.Gly469ArgVAR_018622
3BRAFp.Asp594GlyVAR_018624
4CASP10p.Ala414ValVAR_037430rs28936699

Clinvar genetic disease variations for Non-Hodgkin Lymphoma:

6 (show all 11)
id Gene Name Type Significance SNP ID Assembly Location
1TP53NM_000546.5(TP53): c.974G> T (p.Gly325Val)single nucleotide variantPathogenicrs121912659GRCh37Chr 17, 7576872: 7576872
2PRF1NM_001083116.1(PRF1): c.1122G> A (p.Trp374Ter)single nucleotide variantPathogenicrs104894176GRCh37Chr 10, 72358355: 72358355
3PRF1NM_001083116.1(PRF1): c.755A> G (p.Asn252Ser)single nucleotide variantPathogenicrs28933375GRCh37Chr 10, 72358722: 72358722
4BRAFNM_004333.4(BRAF): c.1405G> C (p.Gly469Arg)single nucleotide variantPathogenicrs121913357GRCh37Chr 7, 140481403: 140481403
5BRAFNM_004333.4(BRAF): c.1406G> C (p.Gly469Ala)single nucleotide variantPathogenicrs121913355GRCh37Chr 7, 140481402: 140481402
6BRAFNM_004333.4(BRAF): c.1781A> G (p.Asp594Gly)single nucleotide variantPathogenicrs121913338GRCh37Chr 7, 140453154: 140453154
7RAD54BNM_012415.3(RAD54B): c.1778A> G (p.Asn593Ser)single nucleotide variantPathogenicrs114216685GRCh37Chr 8, 95403868: 95403868
8RAD54LNM_001142548.1(RAD54L): c.1331T> A (p.Val444Glu)single nucleotide variantPathogenicrs121908689GRCh37Chr 1, 46738430: 46738430
9CASP10NM_032977.3(CASP10): c.1241C> T (p.Ala414Val)single nucleotide variantPathogenicrs28936699GRCh37Chr 2, 202074111: 202074111
10CASP10NM_032977.3(CASP10): c.769C> T (p.Gln257Ter)single nucleotide variantPathogenicrs121909775GRCh37Chr 2, 202070652: 202070652
11CASP10NM_032977.3(CASP10): c.1042_1043insA (p.Gly348Glufs)insertionPathogenicrs398122800GRCh37Chr 2, 202073912: 202073913

Expression for genes affiliated with Non-Hodgkin Lymphoma

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Expression patterns in normal tissues for genes affiliated with Non-Hodgkin Lymphoma

Search GEO for disease gene expression data for Non-Hodgkin Lymphoma.

Pathways for genes affiliated with Non-Hodgkin Lymphoma

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Pathways related to Non-Hodgkin Lymphoma according to GeneCards/GeneDecks:

(show all 25)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.3BRAF, TP53
210.3NBN, TP53
3
Show member pathways
10.3MDM2, TP53
410.3MDM2, TP53
5
Show member pathways
Homologous recombination37
10.2NBN, RAD54B, RAD54L
6
Show member pathways
10.2MDM2, TP53, CASP10
7
Show member pathways
10.2TP53, MDM2, CASP10
810.2TP53, MDM2, CASP10
9
Show member pathways
ErbB receptor signaling network37
ErbB signaling pathway37
10.2BRAF, MDM2, TP53
10
Show member pathways
Signal transduction PTEN pathway60
10.2TP53, BRAF, MDM2
1110.2MDM2, BRAF, TP53
12
Show member pathways
10.2TP53, MDM2, BRAF
1310.2TP53, BRAF, MDM2
14
Show member pathways
DNA damage response37
10.2NBN, TP53, MDM2
1510.2NBN, TP53, MDM2
1610.2TP53, CASP10, BCL6
17
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
10.2BCL6, MDM2, BRAF
1810.2MDM2, BCL6, TP53
19
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
10.2MDM2, BCL6, TP53
2010.2MDM2, TP53, BRAF, RAD54L
2110.1MDM2, CASP10, TP53, BCL6
22
Show member pathways
Immune response CD16 signaling in NK cells60
10.1PRF1, IGK, BRAF, IGH
23
Show member pathways
Immune response IL 4 signaling pathway60
Signal transduction AKT signaling60
10.1TP53, MDM2, IGH, IGK
24
Show member pathways
Apoptosis Modulation and Signaling37
Apoptosis37
10.0MDM2, TP53, PRF1, BCL2L10, CASP10
25
Show member pathways
Immune response BCR pathway60
Fc-epsilon receptor I signaling in mast cells37
10.0IGH, IGK, BRAF, BCL6

Compounds for genes affiliated with Non-Hodgkin Lymphoma

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Compounds related to Non-Hodgkin Lymphoma according to GeneCards/GeneDecks:

(show all 45)
idCompoundScoreTop Affiliating Genes
1n-acetoxy-2-acetylaminofluorene4410.7TP53, HPRT1
2adozelesin4410.7HPRT1, TP53
3bpde4410.6TP53, HPRT1, MDM2
4o6-methylguanine4410.6BRAF, TP53, HPRT1
5amifostine44 1111.6TP53, CSF3, HPRT1
6o6-benzylguanine4410.6HPRT1, TP53
7acnu4410.6TP53, CSF3
810-hydroxycamptothecin4410.6TP53, MDM2
9benzo(a)pyrene4410.6MDM2, TP53, HPRT1
10methylmethanesulfonate4410.6TP53, HPRT1, NBN, MDM2
112-chlorodeoxyadenosine4410.6CSF3, TP53, MDM2
125-methylcytosine44 2411.6HPRT1
13irinotecan44 50 1112.5CSF3, BRAF, MDM2, TP53
14melphalan44 50 1112.5TP53, CSF3, MDM2
15fludarabine44 50 1112.5MDM2, TP53, MS4A1, CSF3
16vinblastine44 50 1112.5CSF3, TP53, MDM2
17hydroxyurea44 50 1112.5CSF3, NBN, TP53, HPRT1
18chlorambucil44 1111.5MDM2, TP53
19adriamycin4410.5MDM2, CSF3, HPRT1, TP53
20geldanamycin44 50 61 1113.5TP53, BRAF, MDM2
21bleomycin44 1111.5TP53, HPRT1, CSF3
22rituximab44 50 1112.5MS4A1, BCL6, CSF3
23vincristine44 50 1112.5BCL6, CSF3, MDM2, TP53
24carboplatin44 50 1112.5TP53, CSF3, MDM2
25thymidylate4410.5HPRT1, MDM2, TP53
26valine4410.5MDM2, CSF3, BRAF, HPRT1
27camptothecin44 61 1112.5TP53, NBN, MDM2
28imatinib44 50 1112.5MDM2, BRAF, CSF3, BCL6
29mitomycin c4410.5MDM2, CSF3, NBN, HPRT1, TP53
30paclitaxel44 50 1112.5TP53, BRAF, CSF3, MDM2, CASP10
31etoposide44 50 61 1113.4CSF3, MDM2, TP53, HPRT1, NBN
32paraffin4410.4BCL6, TP53, BRAF, MDM2, MS4A1
336 mercaptopurine4410.4HPRT1, CSF3
34docetaxel44 50 61 1113.4CSF3, MDM2, TP53
35z-vad-fmk44 6111.4TP53, CASP10
36doxorubicin44 50 1112.4TP53, BCL6, MDM2, NBN, CSF3
37cisplatin44 50 61 1113.4CASP10, CSF3, HPRT1, BRAF, TP53, MDM2
38cycloheximide4410.4CSF3, TP53, BCL6, PRF1, MDM2
39cyclophosphamide44 50 1112.3MDM2, BCL6, HPRT1, MS4A1, TP53, CSF3
40taxane4410.3CSF3, TP53
41curcumin4410.2TP53, HPRT1, MDM2
42thymidine44 2411.2TP53, HPRT1, CSF3, MDM2
43serine4410.2BRAF, NBN, CASP10, TP53, PRF1, HPRT1
445-aza-2deoxycytidine4410.1MDM2, HPRT1, TP53
45aflatoxin b144 2411.0TP53, MDM2

GO Terms for genes affiliated with Non-Hodgkin Lymphoma

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Cellular components related to Non-Hodgkin Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:01660410.3MDM2, TP53
2replication forkGO:0056579.9BCL6, TP53, NBN

Biological processes related to Non-Hodgkin Lymphoma according to GeneCards/GeneDecks:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1DNA strand renaturationGO:00073310.4TP53, RAD54L
2double-strand break repair via homologous recombinationGO:00072410.4RAD54L, RAD54B, NBN
3DNA damage response, signal transduction by p53 class mediatorGO:03033010.4NBN, TP53
4cytolysisGO:01983510.3HPRT1, PRF1
5negative regulation of apoptotic processGO:04306610.1BCL2L10, BRAF, TP53, MDM2
6negative regulation of transcription, DNA-templatedGO:04589210.0BCL7A, BCL6, MDM2, TP53
7protein import into nucleus, translocationGO:00006010.0TP53, BCL6

Molecular functions related to Non-Hodgkin Lymphoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquitin protein ligase bindingGO:03162510.2MDM2, CASP10, TP53
2protein bindingGO:0055159.2MDM2, NBN, TP53, FCRL4, BRAF, PRF1

Products for genes affiliated with Non-Hodgkin Lymphoma

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  • Antibodies
  • Proteins
  • Lysates

Sources for Non-Hodgkin Lymphoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet