MCID: NNH003
MIFTS: 14

Non-Hodgkin Lymphoma, Childhood

Categories: Rare diseases, Immune diseases

Aliases & Classifications for Non-Hodgkin Lymphoma, Childhood

MalaCards integrated aliases for Non-Hodgkin Lymphoma, Childhood:

Name: Non-Hodgkin Lymphoma, Childhood 49

Classifications:



Summaries for Non-Hodgkin Lymphoma, Childhood

MalaCards based summary : Non-Hodgkin Lymphoma, Childhood is related to lymphoma, hodgkin, classic and lymphoma, non-hodgkin, familial. The drugs Methotrexate and deoxycholic acid have been mentioned in the context of this disorder. Affiliated tissues include bone marrow, bone and testes.

Related Diseases for Non-Hodgkin Lymphoma, Childhood

Diseases related to Non-Hodgkin Lymphoma, Childhood via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lymphoma, hodgkin, classic 9.8
2 lymphoma, non-hodgkin, familial 9.8

Symptoms & Phenotypes for Non-Hodgkin Lymphoma, Childhood

Drugs & Therapeutics for Non-Hodgkin Lymphoma, Childhood

Drugs for Non-Hodgkin Lymphoma, Childhood (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 109)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Methotrexate Approved Phase 3,Phase 1,Phase 2 1959-05-2, 59-05-2 126941
2
deoxycholic acid Approved Phase 3 83-44-3 222528
3
Amphotericin B Approved, Investigational Phase 3 1397-89-3 5280965 14956
4
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
5
Nystatin Approved, Vet_approved Phase 3 1400-61-9 11953884
6
Cytarabine Approved, Investigational Phase 3,Phase 1,Phase 2 147-94-4 6253
7
Cyclophosphamide Approved, Investigational Phase 3,Phase 2,Phase 1 50-18-0, 6055-19-2 2907
8
Dexamethasone Approved, Investigational, Vet_approved Phase 3 50-02-2 5743
9
Doxorubicin Approved, Investigational Phase 3 23214-92-8 31703
10
Daunorubicin Approved Phase 3 20830-81-3 30323
11
Vincristine Approved, Investigational Phase 3 2068-78-2, 57-22-7 5978
12
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
13
Thioguanine Approved Phase 3,Phase 1,Phase 2 154-42-7 2723601
14
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
15
Asparaginase Approved, Investigational Phase 3 9015-68-3
16
Levoleucovorin Approved, Investigational Phase 3 68538-85-2
17
leucovorin Approved, Nutraceutical Phase 3,Phase 1,Phase 2 58-05-9 143 6006
18
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 1,Phase 2 59-30-3 6037
19
Doxil Approved June 1999 Phase 3 31703
20 Folic Acid Antagonists Phase 3,Phase 1,Phase 2
21 Cholagogues and Choleretics Phase 3
22 Steroid Synthesis Inhibitors Phase 3
23 Gastrointestinal Agents Phase 3
24 Amphotericin B, deoxycholate drug combination Phase 3
25 Cyclosporins Phase 3,Phase 2,Phase 1
26 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
27 Cytochrome P-450 CYP3A Inhibitors Phase 3
28 Cytochrome P-450 Enzyme Inhibitors Phase 3
29 Nucleic Acid Synthesis Inhibitors Phase 3,Phase 1,Phase 2
30 Hormone Antagonists Phase 3
31 Dermatologic Agents Phase 3,Phase 2,Phase 1
32 Vitamin B Complex Phase 3,Phase 1,Phase 2
33 Hormones Phase 3
34 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
35 Anti-Bacterial Agents Phase 3,Phase 2,Phase 1
36 Anti-Infective Agents Phase 3,Phase 2,Phase 1
37 Antifungal Agents Phase 3,Phase 2,Phase 1
38 Immunosuppressive Agents Phase 3,Phase 2,Phase 1
39 Antimetabolites Phase 3,Phase 2,Phase 1
40 Antimetabolites, Antineoplastic Phase 3,Phase 1,Phase 2
41 Ionophores Phase 3
42 Liposomal amphotericin B Phase 3
43 Antiprotozoal Agents Phase 3
44 Antiparasitic Agents Phase 3
45 Antirheumatic Agents Phase 3,Phase 2,Phase 1
46 Calcineurin Inhibitors Phase 3,Phase 2,Phase 1
47 Calcium, Dietary Phase 3,Phase 2
48 Alkylating Agents Phase 3,Phase 2,Phase 1
49 Topoisomerase Inhibitors Phase 3,Phase 1,Phase 2
50 Peripheral Nervous System Agents Phase 3,Phase 1,Phase 2

Interventional clinical trials:

(show all 25)

# Name Status NCT ID Phase Drugs
1 Graft-Versus-Host Disease Prevention in Treating Patients Who Are Undergoing Bone Marrow Transplantation Completed NCT00002456 Phase 3 cyclosporine;methotrexate
2 Antifungal Therapy for Fever and Neutropenia in Patients Receiving Treatment for Hematologic Cancer Completed NCT00002742 Phase 3 amphotericin B deoxycholate;nystatin
3 Prednisolone or Dexamethasone Combined With Chemotherapy in Treating Young Patients With Newly Diagnosed Lymphoblastic Lymphoma Terminated NCT00275106 Phase 3 asparaginase;cyclophosphamide;cytarabine;daunorubicin hydrochloride;dexamethasone;doxorubicin hydrochloride;leucovorin calcium;mercaptopurine;methotrexate;prednisolone;thioguanine;vincristine sulfate
4 Improve the Survival Rate of Chinese Children and Adolescents With Non-Hodgkin's Lymphoma Completed NCT01761500 Phase 2
5 Statin Therapy in Young Adult Survivors of Childhood Cancer Completed NCT01733953 Phase 2 Atorvastatin;Sugar Pill (Placebo)
6 Mitoxantrone and Clofarabine for Treatment of Recurrent NHL or Acute Leukemia Recruiting NCT01842672 Phase 1, Phase 2 Clofarabine;Mitoxantrone
7 Pediatric MATCH: Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes Recruiting NCT03233204 Phase 2 Olaparib
8 Pediatric MATCH: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations Recruiting NCT03220035 Phase 2 Vemurafenib
9 Pediatric MATCH: Trk Inhibitor LOXO-101 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With NTRK Fusions Recruiting NCT03213704 Phase 2 Larotrectinib
10 Pediatric MATCH: Selumetinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Activating MAPK Pathway Mutations Recruiting NCT03213691 Phase 2 Selumetinib
11 Pediatric MATCH: PI3K/mTOR Inhibitor LY3023414 in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations Recruiting NCT03213678 Phase 2 PI3K/mTOR Inhibitor LY3023414
12 Pediatric MATCH: Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations Recruiting NCT03210714 Phase 2 Erdafitinib
13 Pediatric MATCH: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders Recruiting NCT03155620 Phase 2 Ensartinib;Erdafitinib;Larotrectinib;Olaparib;PI3K/mTOR Inhibitor LY3023414;Selumetinib Sulfate;Tazemetostat;Vemurafenib
14 Pediatric MATCH: Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations Recruiting NCT03213652 Phase 2 Ensartinib
15 Pediatric MATCH: Tazemetostat in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With EZH2, SMARCB1, or SMARCA4 Gene Mutations Recruiting NCT03213665 Phase 2 Tazemetostat
16 Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant Recruiting NCT01251575 Phase 2 Cyclosporine;Fludarabine Phosphate;Mycophenolate Mofetil;Sirolimus
17 Sirolimus and Mycophenolate Mofetil in Preventing GVHD in Patients With Hematologic Malignancies Undergoing HSCT Recruiting NCT02728700 Phase 1, Phase 2 Mycophenolate Mofetil;Sirolimus
18 Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia Recruiting NCT01008462 Phase 2 Carmustine;Cyclophosphamide;Cytarabine;Etoposide;Fludarabine Phosphate;Melphalan;Mycophenolate Mofetil;Tacrolimus
19 Autologous Stem Cell Transplant Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory Lymphoma Active, not recruiting NCT00005803 Phase 1, Phase 2 Carmustine;Cyclophosphamide;Cyclosporine;Cytarabine;Etoposide;Fludarabine Phosphate;Melphalan;Mycophenolate Mofetil
20 Total-Body Irradiation and Fludarabine Phosphate Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies or Kidney Cancer Active, not recruiting NCT00027820 Phase 1, Phase 2 Fludarabine Phosphate;Cyclosporine;Mycophenolate Mofetil
21 Study of 6-Thioguanine in Combination With 6-Mercaptopurine During Maintenance Therapy of Childhood Lymphoma Withdrawn NCT02141100 Phase 1, Phase 2 6-thioguanine
22 BL22 Immunotoxin In Treating Young Patients With Relapsed or Refractory Acute Lymphoblastic Leukemia or Non-Hodgkin's Lymphoma Suspended NCT00077493 Phase 1 BL22 immunotoxin
23 Metabolic Syndrome in Childhood Cancer Survivors Completed NCT00920738
24 Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma Recruiting NCT00897325
25 Dietary and Exercise Interventions in Preventing Cardiovascular Disease in Younger Survivors of Leukemia, Lymphoma, or Brain Tumors Withdrawn NCT02000986

Search NIH Clinical Center for Non-Hodgkin Lymphoma, Childhood

Genetic Tests for Non-Hodgkin Lymphoma, Childhood

Anatomical Context for Non-Hodgkin Lymphoma, Childhood

MalaCards organs/tissues related to Non-Hodgkin Lymphoma, Childhood:

38
Bone Marrow, Bone, Testes, Brain, Kidney

Publications for Non-Hodgkin Lymphoma, Childhood

Variations for Non-Hodgkin Lymphoma, Childhood

Expression for Non-Hodgkin Lymphoma, Childhood

Search GEO for disease gene expression data for Non-Hodgkin Lymphoma, Childhood.

Pathways for Non-Hodgkin Lymphoma, Childhood

GO Terms for Non-Hodgkin Lymphoma, Childhood

Sources for Non-Hodgkin Lymphoma, Childhood

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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