MCID: NNL001
MIFTS: 26

Non-Langerhans-Cell Histiocytosis malady

Summaries for Non-Langerhans-Cell Histiocytosis

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MalaCards: Non-Langerhans-Cell Histiocytosis, also known as histiocytosis, non-langerhans-cell, is related to histiocytosis and langerhans-cell histiocytosis. An important gene associated with Non-Langerhans-Cell Histiocytosis is ACTC1 (actin, alpha, cardiac muscle 1). The compounds s 100 and reticulin have been mentioned in the context of this disorder. Affiliated tissues include pituitary.

Aliases & Classifications for Non-Langerhans-Cell Histiocytosis

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8Disease Ontology, 42NIH Rare Diseases, 60UMLS, 34MeSH, 56SNOMED-CT
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Aliases & Descriptions:

non-langerhans-cell histiocytosis 8
histiocytosis, non-langerhans-cell 42 60
non-langerhans cell histiocytosis 8 42


External Ids:

Disease Ontology8 DOID:4330
SNOMED-CT56 127069007
MeSH34 D015616

Related Diseases for Non-Langerhans-Cell Histiocytosis

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Non-Langerhans-Cell Histiocytosis:



Diseases related to non-langerhans-cell histiocytosis

Clinical Features for Non-Langerhans-Cell Histiocytosis

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Drugs & Therapeutics for Non-Langerhans-Cell Histiocytosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Non-Langerhans-Cell Histiocytosis

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Anatomical Context for Non-Langerhans-Cell Histiocytosis

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32MalaCards
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MalaCards organs/tissues related to Non-Langerhans-Cell Histiocytosis:

32
Pituitary

Animal Models for Non-Langerhans-Cell Histiocytosis or affiliated genes

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Publications for Non-Langerhans-Cell Histiocytosis

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50PubMed
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Articles related to Non-Langerhans-Cell Histiocytosis:

(show all 23)
idTitleAuthorsYear
1
Suprasellar non-Langerhans cell histiocytosis (Erdheim-Chester disease)--a case report. (23465991)
2013
2
Rare case of infratentorial non-Langerhans cell histiocytosis with lethal outcome presenting multiple diagnostic difficulties. (22025140)
2011
3
Retinal manifestations in a patient with xanthoma disseminatum (non-langerhans cell histiocytosis). (21484660)
2011
4
Non-Langerhans cell histiocytosis with isolated CNS involvement: an unusual variant of Erdheim-Chester disease. (20337948)
2010
5
Endolymphatic non-langerhans cell histiocytosis of the larynx: report of an uncommon disease manifestation. (20463609)
2010
6
Intracranial non-Langerhans cell histiocytosis presenting as an isolated intraparenchymal lesion. (20635081)
2010
7
Fibroblastic rheumatism: fibromatosis rather than non-Langerhans cell histiocytosis. (19615014)
2010
8
Cerebral non-Langerhans cell histiocytosis in a 17-year-old patient with a headache: case report. (19363626)
2009
9
Non-Langerhans cell histiocytosis in a child with Kawasaki disease. (21686403)
2009
10
Diffuse xanthogranulomatous dermatitis and systemic Langerhans cell histiocytosis: A novel case that demonstrates bridging between non-Langerhans cell histiocytosis and Langerhans cell histiocytosis. (19022530)
2009
11
Immunohistochemical expression of Langerin in Langerhans cell histiocytosis and non-Langerhans cell histiocytic disorders. (18277880)
2008
12
Successful treatment of Erdheim-Chester disease, a non-Langerhans-cell histiocytosis, with interferon-alpha. (16020507)
2005
13
Erdheim-Chester disease: a non-Langerhans cell histiocytosis. A clinical-case and review of the literature]. (15344569)
2004
14
Primary cerebral non-Langerhans cell histiocytosis: MRI and differential diagnosis. (12221448)
2002
15
Problems in differential diagnosis of non Langerhans cell histiocytosis with pituitary involvement: case report and review of literature. (12665654)
2002
16
Progressive histiocytosis: description of a case of slow-course non-Langerhans cell histiocytosis. (12399681)
2002
17
A child with both Langerhans and non-Langerhans cell histiocytosis. (12383099)
2002
18
Benign cephalic histiocytosis progressing into juvenile xanthogranuloma: a non-Langerhans cell histiocytosis transforming under the influence of a virus? (10698221)
2000
19
Non-Langerhans cell histiocytosis associated with lymphocyte-predominant Hodgkin's disease. (10564322)
1999
20
Generalized non-Langerhans cell histiocytosis: four cases illustrate a spectrum of disease. (7737766)
1995
21
An unusual case of non-Langerhans cell histiocytosis. (8294600)
1994
22
A unique non-Langerhans cell histiocytosis with some features of generalized eruptive histiocytoma. (8034797)
1994
23
Congenital self-healing non-Langerhans cell histiocytosis. (3058480)
1988

Genetic Variations for Non-Langerhans-Cell Histiocytosis

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Expression for genes affiliated with Non-Langerhans-Cell Histiocytosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Non-Langerhans-Cell Histiocytosis

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Pathways for genes affiliated with Non-Langerhans-Cell Histiocytosis

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Compounds for genes affiliated with Non-Langerhans-Cell Histiocytosis

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44Novoseek, 24HMDB, 49PharmGKB, 28IUPHAR, 11DrugBank
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Compounds related to Non-Langerhans-Cell Histiocytosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1s 100449.5ACTC1, F13A1
2reticulin449.5ACTC1, F13A1
3b 723449.4ACTC1, F13A1
4hematoxylin449.3ACTC1, F13A1
5procollagen449.2ACTC1, F13A1
6paraffin449.0F13A1, CD163, ACTC1
7iron44 249.9F13A1, CD163, ACTC1
8vegf448.5ACTC1, SST, F13A1
9dexamethasone44 49 28 1111.3SST, CD163, ACTC1

GO Terms for genes affiliated with Non-Langerhans-Cell Histiocytosis

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Products for genes affiliated with Non-Langerhans-Cell Histiocytosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Non-Langerhans-Cell Histiocytosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet