MCID: NNP006
MIFTS: 12

Nonepidermolytic Palmoplantar Hyperkeratosis malady

Summaries for Nonepidermolytic Palmoplantar Hyperkeratosis

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MalaCards: Nonepidermolytic Palmoplantar Hyperkeratosis is related to epidermolytic acanthoma and cholesteatoma. An important gene associated with Nonepidermolytic Palmoplantar Hyperkeratosis is KRT16 (keratin 16), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds isotretinoin and sodium dodecylsulfate have been mentioned in the context of this disorder.

Aliases & Classifications for Nonepidermolytic Palmoplantar Hyperkeratosis

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20GeneTests
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Aliases & Descriptions:

nonepidermolytic palmoplantar hyperkeratosis 20


Related Diseases for Nonepidermolytic Palmoplantar Hyperkeratosis

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17GeneCards, 18GeneDecks
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Diseases related to Nonepidermolytic Palmoplantar Hyperkeratosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1epidermolytic acanthoma10.0KRT1
2cholesteatoma10.0KRT16
3palmoplantar keratoderma, epidermolytic10.0KRT1, KRT16
4bowen syndrome10.0KRT1, KRT16
5palmoplantar keratosis10.0KRT1, KRT16
6epidermolytic hyperkeratosis10.0KRT16, KRT1
7nonepidermolytic palmoplantar keratoderma10.0KRT16, KRT1
8epidermolysis bullosa simplex10.0KRT1, KRT16
9keratoderma10.0KRT1, KRT16
10keratosis10.0KRT1, KRT16
11skin disease10.0KRT1, KRT16
12squamous cell carcinoma10.0KRT1, KRT16
13lichen planus10.0KRT16, KRT1
14psoriasis10.0KRT1, KRT16

Graphical network of diseases related to Nonepidermolytic Palmoplantar Hyperkeratosis:



Diseases related to nonepidermolytic palmoplantar hyperkeratosis

Clinical Features for Nonepidermolytic Palmoplantar Hyperkeratosis

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Drugs & Therapeutics for Nonepidermolytic Palmoplantar Hyperkeratosis

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Nonepidermolytic Palmoplantar Hyperkeratosis

Drug clinical trials:

Search ClinicalTrials for Nonepidermolytic Palmoplantar Hyperkeratosis

Search NIH Clinical Center for Nonepidermolytic Palmoplantar Hyperkeratosis

Search CenterWatch for Nonepidermolytic Palmoplantar Hyperkeratosis

Genetic Tests for Nonepidermolytic Palmoplantar Hyperkeratosis

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20GeneTests
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Genetic tests related to Nonepidermolytic Palmoplantar Hyperkeratosis:

id Genetic test Affiliating Genes
1 Nonepidermolytic Palmoplantar Hyperkeratosis20 KRT16

Anatomical Context for Nonepidermolytic Palmoplantar Hyperkeratosis

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Animal Models for Nonepidermolytic Palmoplantar Hyperkeratosis or affiliated genes

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Publications for Nonepidermolytic Palmoplantar Hyperkeratosis

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Genetic Variations for Nonepidermolytic Palmoplantar Hyperkeratosis

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Expression for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Search GEO for disease gene expression data for Nonepidermolytic Palmoplantar Hyperkeratosis.

Pathways for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

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12EMD Millipore
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Pathways related to Nonepidermolytic Palmoplantar Hyperkeratosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT1, KRT16

Compounds for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

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44Novoseek, 11DrugBank
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Compounds related to Nonepidermolytic Palmoplantar Hyperkeratosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1isotretinoin44 1110.2KRT1, KRT16
2sodium dodecylsulfate449.2KRT1, KRT16
3retinoid449.1KRT1, KRT16
4steroid449.1KRT1, KRT16
5paraffin449.0KRT16, KRT1
6proline448.8KRT1, KRT16

GO Terms for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

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Products for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Nonepidermolytic Palmoplantar Hyperkeratosis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet