MCID: NNP006

Nonepidermolytic Palmoplantar Hyperkeratosis malady

Summaries for Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Nonepidermolytic Palmoplantar Hyperkeratosis is related to epidermolytic acanthoma and cholesteatoma. An important gene associated with Nonepidermolytic Palmoplantar Hyperkeratosis is KRT16 (keratin 16), and among its related pathways is Cytoskeleton remodeling Keratin filaments. The compounds isotretinoin and sodium dodecylsulfate have been mentioned in the context of this disorder.

Aliases & Classifications for Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
20GeneTests
See all sources

Aliases & Descriptions:

nonepidermolytic palmoplantar hyperkeratosis 20


Related Diseases for Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Nonepidermolytic Palmoplantar Hyperkeratosis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 14)
idRelated DiseaseScoreTop Affiliating Genes
1epidermolytic acanthoma10.0KRT1
2cholesteatoma10.0KRT16
3palmoplantar keratoderma, epidermolytic10.0KRT16, KRT1
4bowen syndrome10.0KRT1, KRT16
5palmoplantar keratosis10.0KRT16, KRT1
6epidermolytic hyperkeratosis10.0KRT16, KRT1
7nonepidermolytic palmoplantar keratoderma10.0KRT1, KRT16
8epidermolysis bullosa simplex10.0KRT16, KRT1
9keratoderma10.0KRT16, KRT1
10keratosis10.0KRT1, KRT16
11skin disease10.0KRT16, KRT1
12squamous cell carcinoma10.0KRT16, KRT1
13lichen planus10.0KRT1, KRT16
14psoriasis10.0KRT16, KRT1

Graphical network of diseases related to Nonepidermolytic Palmoplantar Hyperkeratosis:



Diseases related to nonepidermolytic palmoplantar hyperkeratosis

Clinical Features for Nonepidermolytic Palmoplantar Hyperkeratosis

Drugs & Therapeutics for Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Nonepidermolytic Palmoplantar Hyperkeratosis

Drug clinical trials:

Search ClinicalTrials for Nonepidermolytic Palmoplantar Hyperkeratosis

Search NIH Clinical Center for Nonepidermolytic Palmoplantar Hyperkeratosis

Search CenterWatch for Nonepidermolytic Palmoplantar Hyperkeratosis

Genetic Tests for Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
20GeneTests
See all sources

Genetic tests related to Nonepidermolytic Palmoplantar Hyperkeratosis:

id Genetic test Affiliating Genes
1 Nonepidermolytic Palmoplantar Hyperkeratosis20 KRT16

Anatomical Context for Nonepidermolytic Palmoplantar Hyperkeratosis

Animal Models for Nonepidermolytic Palmoplantar Hyperkeratosis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Nonepidermolytic Palmoplantar Hyperkeratosis

Genetic Variations for Nonepidermolytic Palmoplantar Hyperkeratosis

Expression for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Search GEO for disease gene expression data for Nonepidermolytic Palmoplantar Hyperkeratosis.

Pathways for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
12EMD Millipore
See all sources

Pathways related to Nonepidermolytic Palmoplantar Hyperkeratosis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.1KRT1, KRT16

Compounds for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Sources:
45Novoseek, 11DrugBank
See all sources

Compounds related to Nonepidermolytic Palmoplantar Hyperkeratosis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1isotretinoin45 1110.2KRT1, KRT16
2sodium dodecylsulfate459.2KRT16, KRT1
3retinoid459.1KRT1, KRT16
4steroid459.1KRT16, KRT1
5paraffin459.0KRT1, KRT16
6proline458.8KRT1, KRT16

GO Terms for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

Products for genes affiliated with Nonepidermolytic Palmoplantar Hyperkeratosis

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Nonepidermolytic Palmoplantar Hyperkeratosis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet