NSGCT
MCID: NNS011
MIFTS: 33

Nonseminomatous Germ Cell Tumor (NSGCT) malady

Categories: Rare diseases

Aliases & Classifications for Nonseminomatous Germ Cell Tumor

Aliases & Descriptions for Nonseminomatous Germ Cell Tumor:

Name: Nonseminomatous Germ Cell Tumor 50 69
Non-Seminomatous Germ-Cell Tumors 50
Nsgct 50

Classifications:



Summaries for Nonseminomatous Germ Cell Tumor

NIH Rare Diseases : 50 nonseminomatous germ cell tumors are cancerous tumors commonly found in the pineal gland in the brain, in the mediastinum, or in the abdomen. they originate from cells that were meant to form sex cells (i.e., sperm or eggs). they are often large and have a tendency to spread more quickly than the other type of germ cell tumor (i.e., seminoma type). possible early signs of this cancer include chest pain and breathing problems. last updated: 10/17/2013

MalaCards based summary : Nonseminomatous Germ Cell Tumor, also known as non-seminomatous germ-cell tumors, is related to extragonadal nonseminomatous germ cell tumor and testicular germ cell tumor. An important gene associated with Nonseminomatous Germ Cell Tumor is AFP (Alpha Fetoprotein), and among its related pathways/superpathways is FOXA2 and FOXA3 transcription factor networks. The drugs Dexamethasone and Paclitaxel have been mentioned in the context of this disorder. Affiliated tissues include testis, brain and pineal, and related phenotypes are Increased shRNA abundance (Z-score > 2) and neoplasm

Related Diseases for Nonseminomatous Germ Cell Tumor

Diseases related to Nonseminomatous Germ Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
id Related Disease Score Top Affiliating Genes
1 extragonadal nonseminomatous germ cell tumor 12.3
2 testicular germ cell tumor 11.4
3 teratoma 10.5
4 mediastinitis 10.5
5 infiltrating renal pelvis transitional cell carcinoma 10.3 AFP CGB5
6 severe combined immunodeficiency 10.2 AFP CGB7
7 trypanosomiasis, human east-african 10.2 AFP CGB7
8 bladder carcinoma in situ 10.2 AFP SMUG1
9 growing teratoma syndrome 10.2
10 nutritional deficiency disease 10.2 AFP SMUG1
11 pulmonary artery choriocarcinoma 10.2 ERBB2 SMUG1
12 malignant teratocarcinosarcoma 10.2 AFP CGB5
13 sporadic breast cancer 10.2 AFP SMUG1
14 ovarian cystadenocarcinoma 10.2 CGB5 ERBB2
15 acute serous otitis media 10.2 AFP SMUG1
16 ampulla of vater adenosquamous carcinoma 10.2 AFP SMUG1
17 diabetes mellitus, noninsulin-dependent, 2 10.2 AFP G6PC
18 mature teratoma 10.2
19 trigonocephaly, nonsyndromic 10.2 BRAF ERBB2
20 ovarian germ cell teratoma 10.2 AFP SMUG1
21 rectum leiomyoma 10.2 AFP SMUG1
22 uterine disease 10.2 AFP SMUG1
23 stickler syndrome, type ii 10.1 AFP G6PC
24 postpartum depression 10.1 ERBB2 SMUG1
25 arthus reaction 10.1 AFP ERBB2
26 dementia 10.1 AFP CGB5 SMUG1
27 malignant pleural solitary fibrous tumor 10.1 AFP ERBB2 SMUG1
28 proctitis 10.1 AFP ERBB2 SMUG1
29 sclerosing hemangioma 10.1 AFP ERBB2
30 spastic diplegia infantile type 10.0 BRAF ERBB2
31 prostatitis 10.0
32 choriocarcinoma 10.0
33 inhibited male orgasm 10.0 AFP BRAF SMUG1
34 endometrial small cell carcinoma 10.0 BRAF CSF3
35 extranodal nasal nk/t cell lymphoma 9.9 CSF3 ERBB2
36 extragonadal seminoma 9.9 CSF3 SMUG1
37 subendocardial myocardial infarction 9.9 AFP NUTM1
38 renal cell carcinoma 9.9
39 seizure disorder 9.9
40 hemolytic anemia 9.9
41 leukemia 9.9
42 thrombocytopenia 9.9
43 gynecomastia 9.9
44 endodermal sinus tumor 9.9
45 testicular cancer 9.9
46 embryonal carcinoma 9.9
47 placental site trophoblastic tumor 9.9
48 malignant teratoma 9.9
49 visual cortex disease 9.3 AFP CSF3 G6PC MARCH2 NUTM1 SMUG1
50 atrophic rhinitis 9.2 AFP CGB5 CSF3 G6PC MARCH2 NUTM1

Graphical network of the top 20 diseases related to Nonseminomatous Germ Cell Tumor:



Diseases related to Nonseminomatous Germ Cell Tumor

Symptoms & Phenotypes for Nonseminomatous Germ Cell Tumor

GenomeRNAi Phenotypes related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-110 9.66 BRAF
2 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.66 CGB5 CGB7
3 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.66 BRAF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.66 ERBB2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-163 9.66 ERBB2
6 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.66 BRAF
7 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.66 ERBB2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.66 BRAF
9 Increased shRNA abundance (Z-score > 2) GR00366-A-194 9.66 BRAF
10 Increased shRNA abundance (Z-score > 2) GR00366-A-207 9.66 ERBB2
11 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.66 BRAF
12 Increased shRNA abundance (Z-score > 2) GR00366-A-31 9.66 BRAF
13 Increased shRNA abundance (Z-score > 2) GR00366-A-32 9.66 BRAF CGB5 CGB7 ERBB2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-42 9.66 CGB5 CGB7
15 Increased shRNA abundance (Z-score > 2) GR00366-A-47 9.66 BRAF
16 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.66 ERBB2
17 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.66 ERBB2

MGI Mouse Phenotypes related to Nonseminomatous Germ Cell Tumor:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.02 ERBB2 G6PC SMUG1 AFP BRAF

Drugs & Therapeutics for Nonseminomatous Germ Cell Tumor

Drugs for Nonseminomatous Germ Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 103)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
2
Paclitaxel Approved, Vet_approved Phase 3,Phase 2,Phase 1 33069-62-4 36314
3
Etoposide Approved Phase 3,Phase 2 33419-42-0 36462
4
Cisplatin Approved Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
5
Carboplatin Approved Phase 3,Phase 2,Phase 1 41575-94-4 10339178 498142 38904
6
Bleomycin Approved Phase 3,Phase 2 11056-06-7 5360373
7
Ifosfamide Approved Phase 3,Phase 2,Phase 1 3778-73-2 3690
8
Mechlorethamine Approved Phase 3,Phase 2,Phase 1 51-75-2 4033
9
Oxaliplatin Approved, Investigational Phase 3,Phase 2 61825-94-3 5310940 9887054 6857599, 9887054 43805
10
Mesna Approved Phase 3,Phase 1,Phase 2 3375-50-6 598
11
Lenograstim Approved Phase 2, Phase 3, Phase 1 135968-09-1
12
Diphenhydramine Approved Phase 3 58-73-1, 147-24-0 3100
13
Promethazine Approved Phase 3 60-87-7 4927
14
Vinblastine Approved Phase 3 865-21-4 13342 241903
15
Histamine Approved, Investigational Phase 3 75614-87-8, 51-45-6 774
16
Cyproheptadine Approved Phase 3 129-03-3 2913
17 Dexamethasone acetate Phase 3,Phase 2,Phase 1 1177-87-3
18 Alkylating Agents Phase 3,Phase 2,Phase 1
19 Adjuvants, Immunologic Phase 3,Phase 1,Phase 2
20 Gastrointestinal Agents Phase 3,Phase 2
21 Albumin-Bound Paclitaxel Phase 3,Phase 2,Phase 1
22 Topoisomerase Inhibitors Phase 3,Phase 2
23 Dexamethasone 21-phosphate Phase 3,Phase 2,Phase 1
24 Anti-Bacterial Agents Phase 3,Phase 2
25 Etoposide phosphate Phase 3,Phase 2
26 Isophosphamide mustard Phase 3,Phase 2,Phase 1
27 Antibiotics, Antitubercular Phase 3,Phase 2
28 Antimitotic Agents Phase 3,Phase 2,Phase 1
29 Antineoplastic Agents, Alkylating Phase 3,Phase 2,Phase 1
30 BB 1101 Phase 3,Phase 2,Phase 1
31 Antineoplastic Agents, Phytogenic Phase 3,Phase 2,Phase 1
32 Histamine H2 Antagonists Phase 3
33
Histamine Phosphate Phase 3 51-74-1 65513
34
Serotonin Phase 3 50-67-9 5202
35 Serotonin Agents Phase 3
36 Serotonin Antagonists Phase 3
37 Neurotransmitter Agents Phase 3
38 Histamine Antagonists Phase 3
39 Histamine H1 Antagonists Phase 3
40 Dermatologic Agents Phase 3
41 Anti-Allergic Agents Phase 3
42 Antipruritics Phase 3
43
Mannitol Approved, Investigational Phase 1, Phase 2 69-65-8 453 6251
44
Gemcitabine Approved Phase 2,Phase 1 95058-81-4 60750
45
Furosemide Approved, Vet_approved Phase 1, Phase 2 54-31-9 3440
46
Ranitidine Approved Phase 1, Phase 2 66357-59-3, 66357-35-5 3001055
47
Vincristine Approved, Investigational Phase 2 2068-78-2, 57-22-7 5978
48
Sunitinib Approved, Investigational Phase 2 341031-54-7, 557795-19-4 5329102
49
Fluorouracil Approved Phase 2 51-21-8 3385
50
Levoleucovorin Approved Phase 2 68538-85-2

Interventional clinical trials:

(show all 35)
id Name Status NCT ID Phase
1 Combination Chemotherapy in Treating Patients With Stage II or Stage III Germ Cell Tumors Unknown status NCT00104676 Phase 3
2 Combination Chemotherapy in Treating Men With Germ Cell Cancer Unknown status NCT00003643 Phase 2, Phase 3
3 Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors Recruiting NCT02375204 Phase 3
4 Trial of 1 Cycle of Adjuvant BEP Chemotherapy in High Risk, Stage 1 Non-seminomatous Germ Cell Testis Tumours Active, not recruiting NCT01726374 Phase 3
5 Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors Terminated NCT00072215 Phase 3
6 Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer Terminated NCT01132547 Phase 3
7 Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors Unknown status NCT00127049 Phase 2
8 High-Dose Chemotherapy and Stem Cell Transplant in Treating Patients With Metastatic Germ Cell Tumors That Have Not Responded to First-Line Therapy Unknown status NCT01172912 Phase 2
9 Gemcitabine, Paclitaxel, Ifosfamide, and Cisplatin in Treating Patients With Progressive or Relapsed Metastatic Germ Cell Tumors Unknown status NCT00551122 Phase 1, Phase 2
10 Alvocidib and Oxaliplatin With or Without Fluorouracil and Leucovorin Calcium in Treating Patients With Relapsed or Refractory Germ Cell Tumors Completed NCT00957905 Phase 2
11 Combination Chemotherapy in Treating Male Patients With Germ Cell Tumors Completed NCT00301782 Phase 2
12 Combination Chemotherapy and Pegfilgrastim in Treating Patients With Previously Untreated Germ Cell Tumors Completed NCT00470366 Phase 2
13 Paclitaxel, Ifosfamide, and Carboplatin Followed By Autologous Stem Cell Transplant in Treating Patients With Germ Cell Tumors That Did Not Respond to Cisplatin Completed NCT00423852 Phase 1, Phase 2
14 Ixabepilone in Treating Patients With Advanced Cisplatin-Refractory Germ Cell Tumors Completed NCT00070096 Phase 2
15 Sunitinib in Treating Patients With Metastatic Germ Cell Tumors That Have Relapsed or Not Responded to Treatment Completed NCT00453310 Phase 2
16 Combination Chemotherapy and Pegfilgrastim in Treating Men With Metastatic Germ Cell Tumors Completed NCT00453232 Phase 2
17 Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Relapsed Germ Cell Cancer Completed NCT00002931 Phase 2
18 A Prospective Study of Cabazitaxel in Patients With Non Seminomatous Germ-cell Tumors Recruiting NCT02115165 Phase 2
19 Brentuximab Vedotin in Relapsed/Refractory Germ Cell Tumors Recruiting NCT02689219 Phase 2
20 First Line TIP in Poor Prognosis TGCTs. Recruiting NCT02414685 Phase 2
21 Contribution of the Imaging to the Expression of intégrines αvβ3 for the Characterization of Residual Masses of Non-seminoma Tumors at the End of Chemotherapy Recruiting NCT02317393 Phase 2
22 Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib in Subjects With BRAF V600E- Mutated Rare Cancers Recruiting NCT02034110 Phase 2
23 Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors Recruiting NCT03158064 Phase 2
24 Autologous Peripheral Blood Stem Cell Transplant for Germ Cell Tumors Recruiting NCT00432094 Phase 2
25 PHASE II TRIAL OF THE CYCLIN-DEPEDENT KINASE INHIBITOR PD 0332991 IN PATIENTS WITH CANCER Recruiting NCT01037790 Phase 2
26 Nivolumab and Ipilimumab in Treating Patients With Rare Tumors Recruiting NCT02834013 Phase 2
27 Pembrolizumab in Subjects With Incurable Platinum-Refractory Germ Cell Tumors Active, not recruiting NCT02499952 Phase 2
28 Palifosfamide in Treating Patients With Recurrent Germ Cell Tumors Terminated NCT01808534 Phase 2
29 Lapatinib and Paclitaxel in Treating Patients With Advanced Solid Tumors Completed NCT00313599 Phase 1
30 Follow-up Evaluation Using CT Scans in Patients Who Have Been Treated For Metastatic Testicular Cancer Unknown status NCT00553371
31 Diagnostic Study of Patients With Stage I Testicular Cancer Unknown status NCT00003800
32 Positron Emission Tomography in Detecting Testicle Cancer Completed NCT00045045
33 Cardiac Function and Cardiovascular Risk Profile in Testicular Cancer Patients Completed NCT00705094
34 Swiss Austrian German Testicular Cancer Cohort Study - SAG TCCS Recruiting NCT02229916
35 Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor Active, not recruiting NCT00638898

Search NIH Clinical Center for Nonseminomatous Germ Cell Tumor

Genetic Tests for Nonseminomatous Germ Cell Tumor

Anatomical Context for Nonseminomatous Germ Cell Tumor

MalaCards organs/tissues related to Nonseminomatous Germ Cell Tumor:

39
Testis, Brain, Pineal, Lymph Node, Testes, Prostate, Ovary

Publications for Nonseminomatous Germ Cell Tumor

Articles related to Nonseminomatous Germ Cell Tumor:

(show top 50) (show all 150)
id Title Authors Year
1
Perioperative Morbidity and Mortality Associated With Bleomycin in Primary Mediastinal Nonseminomatous Germ Cell Tumor. ( 27621392 )
2016
2
Laparoscopic Postchemotherapy Retroperitoneal Lymph-Node Dissection Can Be a Standard Option in Defined Nonseminomatous Germ Cell Tumor Patients. ( 27533924 )
2016
3
Intratumoral heterogeneity and chemoresistance in nonseminomatous germ cell tumor of the testis. ( 27861143 )
2016
4
Defining a New Prognostic Index for Stage I Nonseminomatous Germ Cell Tumors Using CXCL12 Expression and Proportion of Embryonal Carcinoma. ( 26453693 )
2016
5
High-Dose Chemotherapy in a Late Relapse, Platinum-Refractory Nonseminomatous Germ Cell Tumor. ( 27055370 )
2016
6
Primary nonseminomatous germ cell tumor in the posterior mediastinum. ( 25473562 )
2014
7
Long term outcome of patients with clinical stage I high-risk nonseminomatous germ cell tumors 15 years after one adjuvant cycle of Bleomycin, Etoposide and Cisplatin chemotherapy. ( 25392157 )
2014
8
Post-chemotherapy laparoscopic retroperitoneal lymph node dissection for nonseminomatous germ cell tumors infiltrating the great vessels. ( 24422683 )
2014
9
Prognostic factors and efficacy of different chemotherapeutic regimens in patients with mediastinal nonseminomatous germ cell tumors. ( 24337455 )
2014
10
Anatomical retroperitoneoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumors: Initial operative experience. ( 24369147 )
2014
11
Growing Teratoma Syndrome After Treatment of a Nonseminomatous Germ Cell Tumor: A Case Report and a Review of Literature. ( 26952048 )
2014
12
Late recurrence of nonseminomatous germ cell tumor successfully treated with intensity-modulated radiation therapy. ( 23868903 )
2013
13
Salvage therapy with high-dose chemotherapy and peripheral blood stem cell transplant in patients with primary mediastinal nonseminomatous germ cell tumors. ( 22892555 )
2013
14
Treatment outcome of patients with extragonadal nonseminomatous germ cell tumors: the Saitama Cancer Center experience. ( 22763659 )
2013
15
Bilateral laparoscopic postchemotherapy retroperitoneal lymph-node dissection in nonseminomatous germ cell tumors--a comparison to template dissection. ( 23516988 )
2013
16
Testicular hilum and vascular invasion predict advanced clinical stage in nonseminomatous germ cell tumors. ( 23238629 )
2013
17
Postchemotherapy laparoscopic retroperitoneal lymph node dissection for low-volume, stage II, nonseminomatous germ cell tumor: first 100 patients. ( 23021090 )
2013
18
Nonseminomatous germ cell tumor of testis and interrupted treatment. ( 24133836 )
2013
19
Re: genomic characterization of testis cancer: association of alterations with outcome of clinical stage 1 mixed germ cell nonseminomatous germ cell tumor of the testis. ( 23845335 )
2013
20
Risk factors for relapse in patients with clinical stage I testicular nonseminomatous germ cell tumors. ( 23400963 )
2013
21
Genomic characterization of testis cancer: association of alterations with outcome of clinical stage 1 mixed germ cell nonseminomatous germ cell tumor of the testis. ( 22503760 )
2012
22
The "growing teratoma syndrome" in primary mediastinal nonseminomatous germ cell tumors: criteria based on current practice. ( 22713299 )
2012
23
Extraperitoneal laparoscopic retroperitoneal lymph node dissection for early-stage testicular nonseminomatous germ cell tumors: initial experience. ( 22524310 )
2012
24
Correlation between retroperitoneal lymph node size and presence of metastases in nonseminomatous germ cell tumors. ( 22180527 )
2012
25
What is the role of enlarged lymph node resection alone in patients with nonseminomatous germ cell tumor who had stage II or III disease? ( 22682983 )
2012
26
Laparoscopic retroperitoneal lymph node dissection for clinical stage I nonseminomatous germ cell tumor: a large single institution experience. ( 22177913 )
2012
27
Gynecomastia as a first clinical sign of nonseminomatous germ cell tumor. ( 21625076 )
2011
28
Management of residual mass in nonseminomatous germ cell tumors following chemotherapy. ( 21969846 )
2011
29
Secondary malignancies among nonseminomatous germ cell tumor cancer survivors. ( 21412759 )
2011
30
Postchemotherapy residual masses in nonseminomatous germ cell tumor patients: 18F-FLT PET is unlikely to identify mature teratoma, but imaging of alphav beta3 integrin expression could. ( 21536932 )
2011
31
Report of the long-term efficacy of two cycles of adjuvant bleomycin/etoposide/cisplatin in patients with stage I testicular nonseminomatous germ-cell tumors (NSGCT): a risk adapted protocol of the Hellenic Cooperative Oncology Group. ( 19362863 )
2011
32
Paclitaxel+BEP (T-BEP) regimen as induction chemotherapy in poor prognosis patients with nonseminomatous germ cell tumors: a phase II study. ( 21764427 )
2011
33
Stage I nonseminomatous germ cell tumor of the testis: more questions than answers? ( 21570606 )
2011
34
Population-based study of treatment guided by tumor marker decline in patients with metastatic nonseminomatous germ cell tumor: a report from the Swedish-Norwegian Testicular Cancer Group. ( 21482994 )
2011
35
Management of low-stage nonseminomatous germ cell tumors of testis: SIU/ICUD Consensus Meeting on Germ Cell Tumors (GCT), Shanghai 2009. ( 21986224 )
2011
36
Trends of retroperitoneal lymphadenectomy use in patients with nonseminomatous germ cell tumor of the testis: a population-based study. ( 21509630 )
2011
37
Non-risk-adapted surveillance in clinical stage I nonseminomatous germ cell tumors: the Princess Margaret Hospital's experience. ( 21190791 )
2011
38
Words of wisdom. Re: management of disseminated nonseminomatous germ cell tumors with risk-based chemotherapy followed by response-guided postchemotherapy surgery. ( 21524725 )
2011
39
Long-term follow-up of Cisplatin combination chemotherapy in patients with disseminated nonseminomatous germ cell tumors: is a postchemotherapy retroperitoneal lymph node dissection needed after complete remission? ( 20026808 )
2010
40
Outcome following resection for patients with primary mediastinal nonseminomatous germ-cell tumors and rising serum tumor markers post-chemotherapy. ( 19889611 )
2010
41
Clinical relevance of HER-2/neu overexpression in patients with testicular nonseminomatous germ cell tumor. ( 20209452 )
2010
42
Influence of suboptimal treatment in patients with mediastinal primary nonseminomatous germ cell tumors. ( 20185939 )
2010
43
Thoracic metastasectomy for nonseminomatous germ cell tumors. ( 20502259 )
2010
44
Paclitaxel plus ifosfamide followed by high-dose carboplatin plus etoposide for patients with relapsed primary mediastinal nonseminomatous germ cell tumors: benefit from chemotherapy, surgery, or both? ( 21060034 )
2010
45
Management of good-risk metastatic nonseminomatous germ cell tumors of the testis: current concepts and controversies. ( 20535293 )
2010
46
Management options for stage 1 nonseminomatous germ cell tumors of the testis. ( 20535290 )
2010
47
Predictive value of modeled AUC(AFP-hCG), a dynamic kinetic parameter characterizing serum tumor marker decline in patients with nonseminomatous germ cell tumor. ( 20472276 )
2010
48
Management of disseminated nonseminomatous germ cell tumors with risk-based chemotherapy followed by response-guided postchemotherapy surgery. ( 20026807 )
2010
49
Nonseminomatous germ cell tumor of the testes metastatic to the corpus cavernosum of the penis. ( 19931126 )
2010
50
Salvage chemotherapy with methotrexate, etoposide and actinomycin D in men with metastatic nonseminomatous germ cell tumors with a choriocarcinoma component: a preliminary report. ( 20731738 )
2010

Variations for Nonseminomatous Germ Cell Tumor

ClinVar genetic disease variations for Nonseminomatous Germ Cell Tumor:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 BRAF NM_004333.4(BRAF): c.1799T> A (p.Val600Glu) single nucleotide variant Pathogenic/Likely pathogenic rs113488022 GRCh37 Chromosome 7, 140453136: 140453136

Expression for Nonseminomatous Germ Cell Tumor

Search GEO for disease gene expression data for Nonseminomatous Germ Cell Tumor.

Pathways for Nonseminomatous Germ Cell Tumor

Pathways related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 10.27 AFP G6PC

GO Terms for Nonseminomatous Germ Cell Tumor

Biological processes related to Nonseminomatous Germ Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 glucose transport GO:0015758 8.96 BRAF G6PC
2 female gamete generation GO:0007292 8.62 CGB5 CGB7

Sources for Nonseminomatous Germ Cell Tumor

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10 dbSNP
11 DGIdb
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18 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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42 MeSH
43 MESH via Orphanet
44 MGI
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48 NDF-RT
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60 QIAGEN
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68 Tocris
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70 UMLS via Orphanet
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