NSIP
MCID: NNS002
MIFTS: 55

Nonspecific Interstitial Pneumonia (NSIP) malady

Respiratory diseases category

Summaries for Nonspecific Interstitial Pneumonia

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. a dry cough and shortness of breath develop over 6 to 18 months. low-grade fever and a feeling of illness (malaise) may occur.

MalaCards: Nonspecific Interstitial Pneumonia, also known as NSIP, is related to pneumonia and pulmonary fibrosis. An important gene associated with Nonspecific Interstitial Pneumonia is FOXF1 (forkhead box F1), and among its related pathways are Rheumatoid arthritis and Malaria. The compounds pge2 and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and b cells, and related mouse phenotypes are vision/eye and muscle.

Wikipedia:63 Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia. more...

Aliases & Classifications for Nonspecific Interstitial Pneumonia

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Sources:
8Disease Ontology, 60UMLS, 48Orphanet, 56SNOMED-CT, 39NCIt, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

nonspecific interstitial pneumonia 8 60
nsip 8 48
non-specific idiopathic interstitial pneumonia 48
non-specific interstitial pneumonia 48


External Ids:

Disease Ontology8 DOID:2801
NCIt39 C35717
ICD10 via Orphanet26 J84.8
SNOMED-CT56 129452008
SNOMED-CT via Orphanet57 129452008
UMLS via Orphanet61 C1290344

Related Diseases for Nonspecific Interstitial Pneumonia

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Nonspecific Interstitial Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 198)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.7HSPG2, CCL2, SFTPC, CXCL5, IL13, IL8
2pulmonary fibrosis31.1IL8, SERPINH1, TGFB1, IL13, CXCR3, CCR4
3idiopathic pulmonary fibrosis31.0CCR4, CCL2, SFTPC, IFNG, FGF2, CXCR3
4interstitial lung disease30.7TGFB1, IL8, SFTPC, CCL2
5vascular disease30.6FGF2, IL8, IL6
6dermatomyositis30.5HSPG2
7connective tissue disease30.4CCL2, IL6, TGFB1
8rheumatoid arthritis30.4IFNG, CCL2, CCR4, HSPG2, CXCR3, CXCL5
9arthritis30.4CCL2, IFNG, FGF2, CXCR3, CXCL5, IL13
10multiple myeloma30.2IL6
11kaposi's sarcoma30.2IL6
12bronchiolitis30.2IL8, IL13
13myeloma30.2IL6, FGF2
14hypertension30.2TGFB1, CCL2
15idiopathic interstitial pneumonia11.0
16acute interstitial pneumonia10.4
17collagen disease10.4
18interstitial emphysema10.3
19pulmonary fibrosis, familial10.3
20cryptogenic organizing pneumonia10.2
21primary biliary cirrhosis10.2
22congestive heart failure10.2
23desquamative interstitial pneumonia10.2
24pulmonary systemic sclerosis10.2
25respiratory bronchiolitis-associated interstitial lung disease10.2
26sarcoma10.2
27scleroderma10.2
28thymoma10.2
29lichen planus10.0CXCR3
30adult t-cell leukemia10.0SERPINH1
31keratoconjunctivitis10.0IL13
32lupus erythematosus10.0IL18
33atopic dermatitis10.0IL13
34nephrotic syndrome10.0IL13
35funisitis10.0SERPINH1
36esophagitis10.0IL13
37purpura10.0HSPG2
38basal cell carcinoma10.0SHH
39parkinson's disease10.0SHH
40periventricular leukomalacia10.0SERPINH1
41cholera10.0HSPG2
42colon cancer10.0HSPG2
43diabetic retinopathy10.0FGF2
44surfactant metabolism dysfunction, pulmonary, 110.0
45erythema multiforme10.0HSPG2
46vasculitis10.0CCL2
47keratitis10.0FGF2
48bladder carcinoma10.0FGF2
49moyamoya disease10.0FGF2
50hyperhomocysteinemia10.0CCL2

Graphical network of the top 20 diseases related to Nonspecific Interstitial Pneumonia:



Diseases related to nonspecific interstitial pneumonia

Clinical Features for Nonspecific Interstitial Pneumonia

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Drugs & Therapeutics for Nonspecific Interstitial Pneumonia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Nonspecific Interstitial Pneumonia

Drug clinical trials:

Search ClinicalTrials for Nonspecific Interstitial Pneumonia

Search NIH Clinical Center for Nonspecific Interstitial Pneumonia

Search CenterWatch for Nonspecific Interstitial Pneumonia

Genetic Tests for Nonspecific Interstitial Pneumonia

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Anatomical Context for Nonspecific Interstitial Pneumonia

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32MalaCards
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MalaCards organs/tissues related to Nonspecific Interstitial Pneumonia:

32
Lung, T cells, B cells

Animal Models for Nonspecific Interstitial Pneumonia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Nonspecific Interstitial Pneumonia:

36 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053919.9FGF2, SFTPC, HSPG2
2MP:00053699.4HSPG2, SHH, FGF2, TGFB1
3MP:00053909.1SERPINH1, IL6, FGF2, SHH
4MP:00053889.0TGFB1, SERPINH1, IL6, CXCR3, FOXF1, SFTPC
5MP:00107719.0IL13, IL6, TGFB1
6MP:00020068.6CCL2, SFTPC, IFNG, CXCR3, IL6, TGFB1
7MP:00053828.5TGFB1, SERPINH1, SHH, IFNG, CCL2, HSPG2
8MP:00053858.4HSPG2, CCL2, SFTPC, IFNG, FOXF1, SHH
9MP:00053767.9HSPG2, CCL2, IFNG, SHH, CXCR3, IL13
10MP:00053817.6HSPG2, CCL2, IFNG, FOXF1, SHH, IL13
11MP:00053867.5HSPG2, CCL2, SFTPC, IFNG, SHH, FGF2
12MP:00053787.2IFNG, SFTPC, CCL2, HSPG2, SHH, IL13
13MP:00053847.1HSPG2, CCL2, IFNG, SHH, FGF2, CXCR3
14MP:00053976.2SHH, IFNG, CCL2, CCR4, HSPG2, FGF2
15MP:00107686.0SHH, FOXF1, IFNG, SFTPC, CCL2, HSPG2
16MP:00053875.5SHH, IFNG, SFTPC, CCL2, CCR4, HSPG2

Publications for Nonspecific Interstitial Pneumonia

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Sources:
50PubMed
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Articles related to Nonspecific Interstitial Pneumonia:

(show top 50)    (show all 116)
idTitleAuthorsYear
1
Proteomic analysis in usual and nonspecific interstitial pneumonia. (24048960)
2013
2
Infliximab-induced nonspecific interstitial pneumonia. (22688498)
2012
3
Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What's the diagnosis? (23206520)
2012
4
Nonspecific interstitial pneumonia: a study of 6 patients with progressive disease. (22173118)
2012
5
Treatment response and long term follow-up results of nonspecific interstitial pneumonia. (22690098)
2012
6
Comparative manifestations and diagnostic accuracy of high-resolution computed tomography in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22759772)
2012
7
Lymphatic fluctuation in the parenchymal remodeling stage of acute interstitial pneumonia, organizing pneumonia, nonspecific interstitial pneumonia and idiopathic pulmonary fibrosis. (22488224)
2012
8
Idiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders? (21273390)
2011
9
Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD). (20483576)
2010
10
HSP47 in lung fibroblasts is a predictor of survival in fibrotic nonspecific interstitial pneumonia. (20129768)
2010
11
Nonspecific interstitial pneumonia pattern as pulmonary involvement in human T-cell lymphotropic virus type 1 carriers. (19856065)
2009
12
Nonspecific interstitial pneumonia: histologic correlation with high-resolution CT in 29 patients. (18242033)
2009
13
Nonspecific interstitial pneumonia after peripheral blood stem cell transplantation in an 11-year-old boy. (19242308)
2009
14
Clinical course and lung function change of idiopathic nonspecific interstitial pneumonia. (18829672)
2009
15
Nonspecific interstitial pneumonia with abundant IgG4-positive cells infiltration, which was thought as pulmonary involvement of IgG4-related autoimmune disease. (18277032)
2008
16
Idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia should stay separate. (18448513)
2008
17
Parenchymal and vascular interactions in the pathogenesis of nonspecific interstitial pneumonia in systemic sclerosis and idiopathic interstitial pneumonia. (18073456)
2008
18
3-T MRI for differentiating inflammation- and fibrosis-predominant lesions of usual and nonspecific interstitial pneumonia: comparison study with pathologic correlation. (18356432)
2008
19
Idiopathic nonspecific interstitial pneumonia: report of an American Thoracic Society project. (18388353)
2008
20
Nonspecific interstitial pneumonia: pathologic features and clinical implications. (17882901)
2007
21
Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? (17556720)
2007
22
Volume histogram analysis for lung thin-section computed tomography: differentiation between usual interstitial pneumonia and nonspecific interstitial pneumonia. (18043360)
2007
23
Idiopathic nonspecific interstitial pneumonia: an unrecognized autoimmune disease? (17881589)
2007
24
High-resolution chest tomography in idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia: utility and challenges. (17940493)
2007
25
Nonspecific interstitial pneumonia. (17195141)
2006
26
Respiratory bronchiolitis-associated interstitial lung disease with fibrosis is a lesion distinct from fibrotic nonspecific interstitial pneumonia: a proposal. (16951670)
2006
27
CT analysis of the anterior mediastinum in idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia. (16969046)
2006
28
Differential diagnosis between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) assessed by high-resolution computed tomography (HRCT). (15973221)
2005
29
Increased levels of interleukin-18 in bronchoalveolar lavage fluid of patients with idiopathic nonspecific interstitial pneumonia. (15753633)
2005
30
Characterization of lymphocyte populations in nonspecific interstitial pneumonia. (16287509)
2005
31
Nonspecific interstitial pneumonia with poor prognosis associated with amyopathic dermatomyositis. (15497521)
2004
32
Video-assisted thoracoscopic lung biopsy as a possible cause of acute interstitial pneumonia in a patient with nonspecific interstitial pneumonia. (15510251)
2004
33
Recruitment maneuver and PEEP response in acute exacerbation of nonspecific interstitial pneumonia. (15281440)
2004
34
Nonspecific interstitial pneumonia: a provisional category of idiopathic interstitial pneumonia. (15316445)
2004
35
Recombinant interferon gamma lb and low dose steroid in two pediatric cases of nonspecific interstitial pneumonia. (15029407)
2004
36
Nonspecific interstitial pneumonia in collagen vascular diseases: comparison of the clinical characteristics and prognostic significance with usual interstitial pneumonia. (14620168)
2003
37
Nonspecific interstitial pneumonia associated with polymyositis and dermatomyositis: serial high-resolution CT findings and functional correlation. (12684299)
2003
38
Different cytokine profiles in usual interstitial pneumonia and nonspecific interstitial pneumonia]. (12899768)
2003
39
Recent advances in the diagnosis and management of nonspecific interstitial pneumonia. (12904713)
2003
40
Myofibroblasts proliferation of idiopathic and collagen vascular disorders associated nonspecific interstitial pneumonia. (12765222)
2003
41
Nonspecific interstitial pneumonia (NSIP), fibrosis pattern. Case report. (12700554)
2003
42
Hypersensitivity pneumonia-nonspecific interstitial pneumonia/fibrosis histopathologic presentation: a study in diagnosis and long-term management. (12602678)
2003
43
Nonspecific interstitial pneumonia as pulmonary involvement of primary SjAPgren's syndrome. (12111081)
2002
44
Nonspecific interstitial pneumonia and systemic sclerosis. (12070054)
2002
45
Statin-induced fibrotic nonspecific interstitial pneumonia. (11936540)
2002
46
Nonspecific interstitial pneumonia (NSIP). (16088690)
2001
47
Increased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumonia. (10988147)
2000
48
Fibroblast contractility: usual interstitial pneumonia and nonspecific interstitial pneumonia. (11112149)
2000
49
Nonspecific interstitial pneumonia: variable appearance at high-resolution chest CT. (11110931)
2000
50
Nonspecific interstitial pneumonia with fibrosis: high-resolution CT and pathologic findings. (9843306)
1998

Genetic Variations for Nonspecific Interstitial Pneumonia

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Expression for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Nonspecific Interstitial Pneumonia

Search GEO for disease gene expression data for Nonspecific Interstitial Pneumonia.

Pathways for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
29KEGG, 52R&D Systems, 37NCBI BioSystems Database, 51QIAGEN, 53Reactome, 12EMD Millipore
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Pathways related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 41)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2IL18
210.2IL18
310.2IL13
410.1IL8
510.1IL8
6
Hide members
10.0IL18, IL13
7
Hide members
9.9IL13, CCL2
89.8SERPINH1, TGFB1
9
Hide members
9.8CCL2, IL8
109.4IFNG, CCL2, IL18
11
Hide members
9.4SLC7A1, SLC7A2, SLC7A6
129.4IL6, IL8, CXCL5
139.3IL8, IL18, IL6
149.3IL6, IL18, IFNG
159.2IL6, IL8, CCL2
169.2CCL2, IL6, TGFB1
17
Cytokine production by Th17 cells in CF (Mouse model)
9.2TGFB1, IL6, IL8
189.2IL6, IFNG, CCL2
199.1IL6, IFNG, IL8
20
Immune response Bacterial infections in normal airways
9.1IL6, IFNG, IL8
219.1IL18, TGFB1, IL13, IFNG
22
Hide members
9.1IFNG, IL6, TGFB1
23
Hide members
9.0IL6, IFNG, IL13, IL18
24
Hide members
9.0CCL2, IL6, IL18, IL8
25
Hide members
9.0CXCL5, CXCR3, CCR4, IL13
268.9IL6, IL8, IFNG, IL18
278.9IL8, IL13, IFNG, IL6
28
Hide members
8.8TGFB1, IL6, IL18, IFNG
298.8TGFB1, IFNG, IL18, IL6
308.7TGFB1, IFNG, IL8, IL6
318.6IL6, IL8, IFNG, IL18, IL13
328.6IL6, FGF2, SHH, IL8, TGFB1
33
Development PDGF signaling via STATs and NF-kB
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8.6CCL2, IL6, IL18, IFNG, FGF2
34
Hide members
8.6TGFB1, IL13, CXCL5, CXCR3, CCR4
35
Hide members
8.5CCR4, CCL2, CXCR3, CXCL5, IL8
368.5IL8, CCR4, CCL2, CXCR3, CXCL5
37
Hide members
8.5CCL2, HSPG2, IL6, IL8, IFNG
38
Hide members
8.4HSPG2, CXCR3, CCR4, CXCL5, IL18, FGF2
39
Hide members
8.3IFNG, IL6, IL18, IL13, IL8, CCL2
40
Hide members
8.2HSPG2, IL8, CXCL5, CXCR3, CCL2, CCR4
41
Hide members
6.8IL6, TGFB1, IL18, FGF2, IL13, CXCL5

Compounds for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 2BitterDB, 59Tocris Bioscience, 49PharmGKB, 24HMDB
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Compounds related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 133)
idCompoundScoreTop Affiliating Genes
1pge24410.5TGFB1
2endotoxin4410.5CXCR3, CXCL5
3gm-csf44 2811.5IFNG
4cycloheximide4410.4IL18, HSPG2
5pentoxifylline44 1111.3IL18, IL13
6hydrocortisone44 2 59 1113.2FGF2, IL8
7indomethacin44 59 28 1113.1HSPG2
8bleomycin44 1111.0SFTPC, FGF2, IL13
9cyclosporin a44 28 5911.9SERPINH1, FGF2, IFNG
10fmlp449.8HSPG2, CXCR3, CXCL5, IL13
11herbimycin a44 5910.7HSPG2, IFNG, IL8
12prednisolone44 28 1111.5CCR4, IL13, FGF2
13mcp 1449.4IL8, CXCR3, CCL2, IL6
14mip 1alpha449.3IL6, IL8, CCL2, IL13
15dexamethasone44 49 28 1112.2SFTPC, FGF2, IL13, TGFB1, IL6
16tetracycline44 1110.2CCL2, IL18, SFTPC, TGFB1, FGF2
17bucillamine449.2IL6, FGF2, IFNG
18imiquimod44 28 59 1112.1IL6, IL8, IL18, IFNG
19rantes449.1IL6, IFNG, CXCR3, TGFB1, CXCL5
20ifn-alpha449.1IL18, IL6, IFNG, CXCR3, IL13
21infliximab44 49 1111.1IL6, IL18, CXCR3, FGF2, IFNG
22etanercept44 49 1111.1IL18, CXCR3, IFNG, IL6, IL8
23lipoteichoic acid449.0IL18, IL8, IL6, CCL2
24polymyxin b449.0CCL2, IFNG, IL8, IL6
25ccl444 2810.0IL13, CCL2, CXCR3, CXCL5, CCR4
26leukotriene b444 59 2411.0CXCL5, IL6, IL8, IL13, CCL2
27thalidomide44 49 59 1112.0IFNG, IL13, IL18, FGF2, IL6
28triptolide448.9CCL2, IFNG, IL8, IL6
29parthenolide44 29.9IL6, IL8, IFNG, CCL2
30groalpha448.8IL18, CCL2, CXCR3, IL8, IL6, CXCL5
3115-deoxy-delta-12,14-prostaglandin j2448.8CCL2, IL6, IFNG, IL8, FGF2
32tgf beta1448.7TGFB1, IL6, IL18, FGF2, IL13, CCL2
33sp 60012544 599.7CCL2, TGFB1, IL13, IL6, IL18, IL8
34il-12448.7IFNG, CCL2, IL6, IL8, IL18, IL13
35polyinosinic-polycytidylic acid448.6IL8, IL6, IL18, IFNG
36pdtc448.5IL8, IL18, CCL2, IFNG, IL6, TGFB1
37thymidine44 249.1IL6, TGFB1, CXCR3, FGF2, IL13, IL18
38il 10448.1IFNG, CXCR3, IL8, CCL2, IL18, IL6
39arginine448.0IL13, CCL2, IFNG, CXCR3, IL18, SLC7A1
40tarc448.0CCR4, CCL2, IL8, IL18, IL13, CXCL5
41actinomycin d448.0CCL2, TGFB1, IL6, IL8, FGF2, IFNG
42sb 20358044 599.0FGF2, CCL2, IFNG, IL13, IL18, TGFB1
43pd 98,059447.9HSPG2, IL18, IL8, IL6, TGFB1, CXCR3
44ly294002447.9CXCR3, TGFB1, IL8, IL18, IL13, FGF2
45simvastatin44 49 59 28 11 2412.8IL18, IFNG, CCR4, IL8, IL6, CCL2
46histamine44 28 249.8IL6, TGFB1, IL8, CXCR3, IFNG, CCL2
47ccl344 288.5IFNG, CXCL5, IL18, IL8, IL6, CXCR3
48nitric oxide44 11 249.5SERPINH1, IFNG, SLC7A2, SLC7A1, IL13, CXCR3
49retinoic acid44 248.2IL6, IFNG, IL18, FGF2, CCR4, HSPG2
50vegf446.9HSPG2, CCL2, SFTPC, IL6, TGFB1, SERPINH1

GO Terms for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
16Gene Ontology
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Cellular components related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.2IFNG, CXCR3, IL13, IL6, CCR4
2extracellular regionGO:0055766.8HSPG2, CCL2, IFNG, FGF2, CXCL5, IL13
3extracellular spaceGO:0056156.3TGFB1, HSPG2, CCL2, SFTPC, IFNG, SHH

Biological processes related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 39)
idNameGO IDScoreTop Affiliating Genes
1lung lobe morphogenesisGO:06046310.4FOXF1, SHH
2renal system developmentGO:07200110.3SHH, FOXF1
3stem cell developmentGO:04886410.3SHH, FGF2
4embryonic foregut morphogenesisGO:04861710.2SHH, FOXF1
5cellular response to mechanical stimulusGO:07126010.1IL18, IL13, SFTPC
6positive regulation of superoxide anion generationGO:03293010.1IL18, TGFB1
7response to hyperoxiaGO:05509310.0IL18, SFTPC
8epithelial cell proliferation involved in salivary gland morphogenesisGO:06066410.0SHH, IL6
9positive regulation of interleukin-17 productionGO:03274010.0TGFB1, IL18
10regulation of vascular endothelial growth factor productionGO:01057410.0CCL2, IL6
11lung developmentGO:0303249.9FOXF1, SHH, FGF2, IL18
12neutrophil apoptotic processGO:0017819.9IFNG, IL6
13positive regulation of cell divisionGO:0517819.9TGFB1, FGF2, SHH
14lipopolysaccharide-mediated signaling pathwayGO:0316639.9TGFB1, IL18, CCL2
15cellular response to tumor necrosis factorGO:0713569.9IL8, IL18, CCL2
16branching involved in salivary gland morphogenesisGO:0604459.8IL6, SHH
17angiogenesisGO:0015259.8IL18, CXCR3, CCL2, HSPG2
18cell-cell signalingGO:0072679.8IL18, IL13, CXCL5, SHH
19MAPK cascadeGO:0001659.8TGFB1, IL18, CCL2
20amino acid transportGO:0068659.8SLC7A2, SLC7A6, SLC7A1
21hyaluronan catabolic processGO:0302149.7FGF2, TGFB1
22cellular response to organic cyclic compoundGO:0714079.7TGFB1, IL18, FOXF1, CCL2
23response to glucocorticoid stimulusGO:0513849.7IL6, SFTPC, CCL2
24neutrophil chemotaxisGO:0305939.7IL8, IFNG, CCL2
25negative regulation of blood vessel endothelial cell migrationGO:0435379.6FGF2, TGFB1
26cellular component movementGO:0069289.6IL8, IL13, CXCR3, IFNG
27cellular response to lipopolysaccharideGO:0712229.6CCL2, IFNG, IL8
28positive regulation of protein import into nucleusGO:0423079.5SHH, TGFB1
29humoral immune responseGO:0069599.5IL6, IFNG, CCL2
30endoplasmic reticulum unfolded protein responseGO:0309689.5CCL2, IFNG, IL8
31extracellular matrix organizationGO:0301989.5HSPG2, FOXF1, FGF2, SERPINH1, TGFB1
32agingGO:0075689.3CCL2, IL6, TGFB1
33positive regulation of cell proliferationGO:0082849.1SHH, FGF2, CXCL5, IL6, TGFB1
34positive regulation of transcription, DNA-dependentGO:0458939.1FOXF1, SHH, FGF2, IL6, TGFB1
35chemotaxisGO:0069359.0CCR4, CCL2, FGF2, CXCR3, CXCL5
36immune responseGO:0069559.0CCR4, CXCL5, IL13, IL18, IL8
37response to drugGO:0424938.9CCL2, IFNG, IL6, TGFB1
38positive regulation of transcription from RNA polymerase II promoterGO:0459448.7IFNG, FOXF1, SHH, FGF2, IL6, TGFB1
39inflammatory responseGO:0069547.7TGFB1, CCR4, CCL2, CXCR3, IL13, IL18

Molecular functions related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:0080099.6IL8, CXCL5, CCL2
2cytokine activityGO:0051258.4IL6, IL18, IL13, FGF2, IFNG

Products for genes affiliated with Nonspecific Interstitial Pneumonia

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  • Antibodies
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Sources for Nonspecific Interstitial Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet