NSIP
MCID: NNS002
MIFTS: 58

Nonspecific Interstitial Pneumonia (NSIP) malady

Respiratory diseases, Rare diseases categories
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Summaries for Nonspecific Interstitial Pneumonia

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Disease Ontology:8 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. a dry cough and shortness of breath develop over 6 to 18 months. low-grade fever and a feeling of illness (malaise) may occur.

MalaCards based summary: Nonspecific Interstitial Pneumonia, also known as NSIP, is related to interstitial lung disease and bronchiolitis. An important gene associated with Nonspecific Interstitial Pneumonia is FOXF1 (forkhead box F1), and among its related pathways are MSP-RON Signaling and Endochondral Ossification. The compounds ccl4 and mcp 1 have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and b cells, and related mouse phenotypes are craniofacial and embryogenesis.

Wikipedia:65 Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia. more...

Aliases & Classifications for Nonspecific Interstitial Pneumonia

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Sources:
8Disease Ontology, 62UMLS, 48Orphanet, 39NCIt, 57SNOMED-CT, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Nonspecific Interstitial Pneumonia, Aliases & Descriptions:

Name: Nonspecific Interstitial Pneumonia 8 62
Nsip 8 48
Non-Specific Idiopathic Interstitial Pneumonia 48
 
Non-Specific Interstitial Pneumonia Nos 62
Non-Specific Interstitial Pneumonia 48


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Respiratory diseases


External Ids:

Disease Ontology8 DOID:2801
NCIt39 C35717
SNOMED-CT57 129452008
ICD10 via Orphanet26 J84.8
UMLS via Orphanet63 C1290344

Related Diseases for Nonspecific Interstitial Pneumonia

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Diseases related to Nonspecific Interstitial Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 130)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial lung disease31.1CCL2
2bronchiolitis30.8IL13, IL8
3arthritis30.7IL6, IL8
4pneumonia30.7IL13, IL6, IL8, CCL2, CXCL5, TGFB1
5vascular disease30.5IL8, IL6, FGF2
6connective tissue disease30.5IL6, CCL2, TGFB1
7tuberculosis30.4CXCR3, CCR4, IFNG, IL18
8pulmonary fibrosis30.3IL13, IL8, CCR4, CCL2, CXCR3, SERPINH1
9idiopathic pulmonary fibrosis29.1SFTPC, TGFB1, SERPINH1, CXCR3, FGF2, IL13
10rheumatoid arthritis28.9IL13, IL6, IL8, IL18, IFNG, CCR4
11usual interstitial pneumonia11.0
12idiopathic interstitial pneumonia10.6
13funisitis10.6SERPINH1
14cervical incompetence10.5SERPINH1
15adult t-cell leukemia10.5SERPINH1
16pars planitis10.4CXCR3, CCR4
17malaria10.4IFNG
18contact dermatitis10.4CCR4, CXCR3
19lymphomatoid papulosis10.4CCR4, CXCR3
20periapical granuloma10.4CXCR3, CCL2
21acute interstitial pneumonia10.4
22dermatomyositis10.4
23allergic contact dermatitis10.4CCR4, CXCR3
24vacterl association10.4SHH, FOXF1
25proliferative glomerulonephritis10.3CXCR3, CCL2
26pulmonary alveolar proteinosis10.3SFTPC, CCL2
27lipoid nephrosis10.3IL13, CCL2
28adult-onset still's disease10.3IL18, IL6
29bronchiolitis obliterans10.3CXCR3, IL8
30congestive heart failure10.3
31primary biliary cirrhosis10.3
32cryptogenic organizing pneumonia10.3
33pulmonary function10.3
34pulmonary eosinophilia10.3IL8, IL13
35bacterial vaginosis10.2IL8, SERPINH1
36hypertension10.2
37multiple myeloma10.2
38pulmonary hypertension10.2
39desquamative interstitial pneumonia10.2
40respiratory bronchiolitis-associated interstitial lung disease10.2
41kaposi's sarcoma10.2
42hermansky-pudlak syndrome10.2
43myeloma10.2
44sarcoma10.2
45scleroderma10.2
46thymoma10.2
47amyopathic dermatomyositis10.2
48polymyositis10.2
49cork-handlers' disease10.2IL8, CXCL5, SFTPC
50cutaneous leishmaniasis10.2IL13, IFNG

Graphical network of the top 20 diseases related to Nonspecific Interstitial Pneumonia:



Diseases related to nonspecific interstitial pneumonia

Symptoms for Nonspecific Interstitial Pneumonia

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Drugs & Therapeutics for Nonspecific Interstitial Pneumonia

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Drug clinical trials:

Search ClinicalTrials for Nonspecific Interstitial Pneumonia

Search NIH Clinical Center for Nonspecific Interstitial Pneumonia

Genetic Tests for Nonspecific Interstitial Pneumonia

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Anatomical Context for Nonspecific Interstitial Pneumonia

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MalaCards organs/tissues related to Nonspecific Interstitial Pneumonia:

32
Lung, T cells, B cells

Animal Models for Nonspecific Interstitial Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Nonspecific Interstitial Pneumonia:

36 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.1SHH, HSPG2, TGFB1, SERPINH1, CCL2, IFNG
2MP:00053808.1SHH, HSPG2, TGFB1, SERPINH1, FOXF1, IFNG
3MP:00053678.0IL6, IFNG, CXCR3, TGFB1, SHH
4MP:00053897.7SFTPC, SHH, TGFB1, CCL2, IFNG, IL13
5MP:00053907.6SHH, HSPG2, SERPINH1, CCL2, IFNG, IL6
6MP:00053707.5HSPG2, TGFB1, CCL2, IFNG, IL6
7MP:00020067.2SFTPC, SHH, TGFB1, CXCR3, CCL2, IFNG
8MP:00107717.1SHH, HSPG2, TGFB1, CCL2, IFNG, IL18
9MP:00053916.8SFTPC, SHH, HSPG2, TGFB1, CCL2, IFNG
10MP:00053696.8SHH, HSPG2, TGFB1, FOXF1, CCL2, IFNG
11MP:00053816.7SHH, HSPG2, TGFB1, SERPINH1, FOXF1, CCL2
12MP:00053866.7SFTPC, SHH, HSPG2, TGFB1, CCL2, IFNG
13MP:00036316.7SHH, HSPG2, TGFB1, SERPINH1, CCL2, IFNG
14MP:00053786.6SFTPC, SHH, HSPG2, TGFB1, SERPINH1, CCL2
15MP:00053846.5SHH, HSPG2, TGFB1, CXCR3, CCL2, IFNG
16MP:00053886.4IL13, SFTPC, SHH, HSPG2, TGFB1, SERPINH1
17MP:00053766.4CXCR3, TGFB1, HSPG2, SHH, CCL2, IFNG
18MP:00053856.1SERPINH1, TGFB1, HSPG2, SHH, SFTPC, CXCR3
19MP:00107685.8SERPINH1, TGFB1, HSPG2, SHH, SFTPC, CXCR3
20MP:00053875.7CXCR3, TGFB1, HSPG2, SHH, SFTPC, CCL2
21MP:00053975.6CCL2, CXCR3, TGFB1, HSPG2, SHH, CCR4

Publications for Nonspecific Interstitial Pneumonia

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Articles related to Nonspecific Interstitial Pneumonia:

(show top 50)    (show all 122)
idTitleAuthorsYear
1
Hermansky-Pudlak syndrome with nonspecific interstitial pneumonia. (24583434)
2014
2
Nonspecific interstitial pneumonia and usual interstitial pneumonia: is differentiation possible by high-resolution computed tomography? (24480140)
2014
3
Nonspecific interstitial pneumonia: clinical associations and outcomes. (25380997)
2014
4
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
5
Airspace enlargement with fibrosis shows characteristic histology and immunohistology different from usual interstitial pneumonia, nonspecific interstitial pneumonia and centrilobular emphysema. (23692421)
2013
6
Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia. (22558525)
2012
7
Infliximab-induced nonspecific interstitial pneumonia. (22688498)
2012
8
Usual interstitial pneumonia and nonspecific interstitial pneumonia: correlation between CT findings at the site of biopsy with pathological diagnoses. (22169358)
2012
9
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
10
Idiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders? (21273390)
2011
11
Thalidomide induced nonspecific interstitial pneumonia in patient with relapsed multiple myeloma. (21179284)
2010
12
Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD). (20483576)
2010
13
Understanding nonspecific interstitial pneumonia: the need for a diagnostic gold standard. (19158329)
2009
14
Nonspecific interstitial pneumonia pattern as pulmonary involvement in human T-cell lymphotropic virus type 1 carriers. (19856065)
2009
15
Nonspecific interstitial pneumonia: histologic correlation with high-resolution CT in 29 patients. (18242033)
2009
16
Nonspecific interstitial pneumonia (NSIP) associated with anti-KS antibody: differentiation from idiopathic NSIP. (19652435)
2009
17
Nonspecific interstitial pneumonia with abundant IgG4-positive cells infiltration, which was thought as pulmonary involvement of IgG4-related autoimmune disease. (18277032)
2008
18
Idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia should stay separate. (18448513)
2008
19
Expression of chemokine receptors CXCR3 and CCR4 in lymphocytes of idiopathic nonspecific interstitial pneumonia. (17137778)
2007
20
Nonspecific interstitial pneumonia: pathologic features and clinical implications. (17882901)
2007
21
Idiopathic nonspecific interstitial pneumonia: lung manifestation of undifferentiated connective tissue disease? (17556720)
2007
22
Volume histogram analysis for lung thin-section computed tomography: differentiation between usual interstitial pneumonia and nonspecific interstitial pneumonia. (18043360)
2007
23
Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia. (16448649)
2006
24
Nonspecific interstitial pneumonia. (17195141)
2006
25
Iatrogenic Kaposi's sarcoma following steroid therapy for nonspecific interstitial pneumonia with HHV-8 genotyping. (16413694)
2006
26
Respiratory bronchiolitis-associated interstitial lung disease with fibrosis is a lesion distinct from fibrotic nonspecific interstitial pneumonia: a proposal. (16951670)
2006
27
Differential diagnosis between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) assessed by high-resolution computed tomography (HRCT). (15973221)
2005
28
Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. (16272854)
2005
29
Comparison of BALF concentrations of ENA-78 and IP10 in patients with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia. (16085216)
2005
30
Increased levels of interleukin-18 in bronchoalveolar lavage fluid of patients with idiopathic nonspecific interstitial pneumonia. (15753633)
2005
31
High-resolution computed tomography features of nonspecific interstitial pneumonia and usual interstitial pneumonia. (15891504)
2005
32
Nonspecific interstitial pneumonia with poor prognosis associated with amyopathic dermatomyositis. (15497521)
2004
33
High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia. (15481270)
2004
34
Nonspecific interstitial pneumonia in collagen vascular diseases: comparison of the clinical characteristics and prognostic significance with usual interstitial pneumonia. (14620168)
2003
35
BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia. (12952254)
2003
36
Nonspecific interstitial pneumonia associated with polymyositis and dermatomyositis: serial high-resolution CT findings and functional correlation. (12684299)
2003
37
Different cytokine profiles in usual interstitial pneumonia and nonspecific interstitial pneumonia]. (12899768)
2003
38
Nonspecific interstitial pneumonia: correlation between thin-section CT findings and pathologic subgroups in 55 patients. (12355005)
2002
39
Nonspecific interstitial pneumonia as pulmonary involvement of primary SjAPgren's syndrome. (12111081)
2002
40
Survival of patients with biopsy-proven usual interstitial pneumonia and nonspecific interstitial pneumonia. (12108865)
2002
41
Nonspecific interstitial pneumonia and systemic sclerosis. (12070054)
2002
42
Nonspecific interstitial pneumonia/fibrosis completely recovered by adding cyclophosphamide to corticosteroids. (12413012)
2002
43
The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumonia. (12108451)
2002
44
An unusual case of nonspecific interstitial pneumonia treated initially with surgical resection. (12380731)
2002
45
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparative appearances at and diagnostic accuracy of thin-section CT. (11719652)
2001
46
Increased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumonia. (10988147)
2000
47
Fibroblast contractility: usual interstitial pneumonia and nonspecific interstitial pneumonia. (11112149)
2000
48
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis. (10471616)
1999
49
Nonspecific interstitial pneumonia with fibrosis: radiographic and CT findings in seven patients. (7753988)
1995
50
Nonspecific interstitial pneumonia/fibrosis. Histologic features and clinical significance. (8291652)
1994

Variations for Nonspecific Interstitial Pneumonia

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Expression for genes affiliated with Nonspecific Interstitial Pneumonia

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Expression patterns in normal tissues for genes affiliated with Nonspecific Interstitial Pneumonia

Search GEO for disease gene expression data for Nonspecific Interstitial Pneumonia.

Pathways for genes affiliated with Nonspecific Interstitial Pneumonia

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Pathways related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 60)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.3CCL2, IFNG, IL18
29.2FGF2, SERPINH1, TGFB1
3
Show member pathways
Proteogylcan syndecan-mediated signaling events37
9.1FGF2, TGFB1, HSPG2
49.0IL6, CCL2, CXCL5
59.0IL6, IL8, CXCL5
68.9IL6, IL8, IL18
7
Show member pathways
Type III interferon signaling37
8.8IL13, IL6, IFNG
8
Show member pathways
8.8HSPG2, TGFB1, SERPINH1, FGF2
98.8CCL2, IL8, IL6
108.8IFNG, IL18, IL6
11
Show member pathways
thioredoxin pathway37
8.8IL6, IFNG, CCL2
128.7TGFB1, IL6, IL13
138.7TGFB1, IFNG, IL18, IL13
148.7IL6, IL8, IFNG
158.7IL6, IL8, IFNG
16
Show member pathways
Immune response MIF in innate immunity response60
8.7IL6, IL8, IFNG
17
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
8.7IFNG, IL8, IL6
18
Show member pathways
8.6CXCR3, CXCL5, CCL2, CCR4, IL8
19
Show member pathways
8.6CXCR3, CXCL5, CCL2, CCR4, IL8
20
Show member pathways
8.6TGFB1, IL8, IL6
21
Show member pathways
8.5TGFB1, IFNG, IL6
228.5IL6, IFNG, TGFB1
23
Show member pathways
8.5IL6, IL8, IL18, CCL2
248.4IFNG, IL8, IL6, IL13
25
Show member pathways
8.4IFNG, IL18, IL8, IL6
26
Show member pathways
8.3SHH, CXCR3, CXCL5, CCL2, CCR4, IL8
27
Show member pathways
8.3HSPG2, TGFB1, IL6, FGF2
28
Show member pathways
8.2TGFB1, CCL2, IL6, FGF2
298.2IL13, IL6, IFNG, TGFB1
30
Show member pathways
IL27-mediated signaling events37
8.2IL6, IL18, IFNG, TGFB1
318.2IL6, IL18, IFNG, TGFB1
328.1TGFB1, IFNG, IL8, IL6
338.1IFNG, IL18, IL8, IL6, IL13
348.1IL6, IL8, IFNG, TGFB1
35
Show member pathways
IL23-mediated signaling events37
Immune response IL 10 signaling pathway60
Angiopoietin receptor Tie2-mediated signaling37
Development PDGF signaling via STATs and NF kB60
Development Angiopoietin Tie2 signaling60
8.0CCL2, IFNG, IL18, IL6, FGF2
36
Show member pathways
7.9IL13, IL6, IL18, IFNG, TGFB1
37
Show member pathways
7.9TGFB1, IFNG, IL18, IL6, IL13
387.9SHH, TGFB1, IL8, IL6, FGF2
39
Show member pathways
7.7CCL2, IFNG, IL18, IL8, IL6, IL13
407.7TGFB1, CCL2, IFNG, IL8, IL6
41
Show member pathways
7.7HSPG2, TGFB1, CXCR3, CXCL5, CCL2, CCR4
427.4TGFB1, CCL2, IFNG, IL18, IL8, IL6
43
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
7.3HSPG2, TGFB1, CCL2, IFNG, IL8, IL6
447.1IL6, TGFB1, CXCL5, CCL2, IFNG, IL18
45
Show member pathways
7.0SHH, HSPG2, TGFB1, CXCR3, CXCL5, CCL2
46
Show member pathways
6.6TGFB1, CCL2, IFNG, IL18, IL8, IL6
47
Show member pathways
6.2IL13, IL6, IL8, IL18, CCR4, CCL2
48
Show member pathways
6.2TGFB1, FGF2, IL13, IL6, IL8, IL18
49
Show member pathways
6.0TGFB1, CXCR3, CXCL5, CCL2, CCR4, IFNG
50
Show member pathways
5.8CXCL5, CXCR3, TGFB1, HSPG2, CCL2, CCR4

Compounds for genes affiliated with Nonspecific Interstitial Pneumonia

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Compounds related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 179)
idCompoundScoreTop Affiliating Genes
1ccl444 2810.1CCR4, CCL2, CXCL5, CXCR3, IL13
2mcp 1448.9CCL2, IL8, CXCR3, IL6
3fmlp448.8IL13, HSPG2, CCL2, CXCL5, CXCR3, IL8
4mip 1alpha448.8CCL2, IL13, IL6, IL8
5bleomycin44 119.8FGF2, CCL2, SFTPC, IL13, TGFB1
6tetracycline44 119.8SFTPC, FGF2, CCL2, TGFB1, IL18
7imiquimod44 61 28 1111.6IFNG, IL6, IL8, IL18
8ifn-alpha448.6IL6, CXCR3, IL18, IFNG, IL13
9lipoteichoic acid448.5IL8, CCL2, IL18, IL6
10infliximab44 50 1110.5IL6, IL18, CXCR3, FGF2, IFNG
11leukotriene b444 61 2410.5CXCL5, IL6, IL13, CCL2, IL8
12etanercept44 50 1110.5IFNG, IL18, IL8, CXCR3, IL6
13polymyxin b448.5CCL2, IFNG, IL8, IL6
14triptolide448.4CCL2, IL6, IL8, IFNG
15pentoxifylline44 119.4IL8, IFNG, IL13, IL6, IL18
16parthenolide44 29.4CCL2, IFNG, IL8, IL6
17thalidomide44 50 61 1111.3IL18, IL6, IL13, FGF2, IFNG
1815-deoxy-delta-12,14-prostaglandin j2448.2IFNG, FGF2, IL8, CCL2, IL6
19groalpha448.1CXCR3, IL6, CXCL5, CCL2, IL18, IL8
20il-12448.1IL6, IL13, IL8, IL18, IFNG, CCL2
21hydrocortisone44 2 61 1111.1IL13, IL6, IL8, CXCR3, IFNG, FGF2
22polyinosinic-polycytidylic acid448.1IL6, IFNG, IL18, IL8
23tgf beta1448.0IL6, IL13, TGFB1, IL18, CCL2, FGF2
24sp 60012544 619.0TGFB1, IL8, IL18, IL13, IL6, CCL2
25prednisolone44 28 1110.0CCR4, IFNG, IL18, IL13, FGF2, IL6
26tarc447.9IL13, CXCR3, CXCL5, CCL2, IL8, IL18
27herbimycin a44 618.9IL6, HSPG2, CCL2, IFNG, IL8, FGF2
28hyaluronic acid44 248.9IL6, IL13, TGFB1, IL8, FGF2
29pdtc447.8IL18, CCL2, TGFB1, IL6, IL8, IFNG
30indomethacin44 28 61 1110.7IL18, TGFB1, IFNG, HSPG2, IL13, IL6
31endotoxin447.6IL8, IL13, IL6, IL18, IFNG, CCL2
32simvastatin44 50 61 28 24 1112.5HSPG2, CCL2, CCR4, IFNG, IL18, IL8
33gm-csf44 288.5CCL2, IFNG, IL18, IL8, IL6, IL13
34thymidine44 248.5IL18, TGFB1, IL6, FGF2, CXCR3, IFNG
35nitric oxide44 24 119.3IL8, IL13, CXCR3, CCL2, CXCL5, SERPINH1
36il 10447.2TGFB1, CXCR3, CCL2, IFNG, IL18, IL8
37cyclosporin a44 28 619.1IL8, IL6, IFNG, FGF2, TGFB1, SERPINH1
38actinomycin d447.1TGFB1, FGF2, CCL2, IFNG, IL8, IL6
39ccl344 288.1IL13, IL6, IL8, IL18, CXCR3, CXCL5
40sb 20358044 618.1TGFB1, CCL2, IFNG, IL18, IL8, IL6
41serine447.0IL8, HSPG2, TGFB1, SERPINH1, IL13, CXCR3
42pd 98,059447.0HSPG2, TGFB1, CXCR3, CCL2, IL8, FGF2
43ly294002447.0HSPG2, FGF2, TGFB1, CXCR3, CCL2, IL18
44histamine44 28 248.9TGFB1, CXCR3, IFNG, CCL2, IL13, IL6
45retinoic acid44 247.7FGF2, IL13, IL18, IFNG, TGFB1, HSPG2
46cycloheximide446.5IL8, IL18, IFNG, FGF2, TGFB1, HSPG2
47rantes446.5CXCR3, CXCL5, CCL2, CCR4, IFNG, IL18
48pge2446.2FGF2, HSPG2, TGFB1, IL13, IL6, IL8
49dexamethasone44 50 28 119.0CXCR3, TGFB1, HSPG2, SFTPC, CXCL5, IL13
50vegf445.7CXCL5, CXCR3, SERPINH1, HSPG2, SFTPC, TGFB1

GO Terms for genes affiliated with Nonspecific Interstitial Pneumonia

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Cellular components related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.1CCR4, IFNG, IL6, IL13, CXCR3
2extracellular regionGO:0055765.8HSPG2, TGFB1, CXCL5, CCL2, IFNG, IL18
3extracellular spaceGO:0056155.2FGF2, SFTPC, SHH, HSPG2, TGFB1, SERPINH1

Biological processes related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 59)
idNameGO IDScoreTop Affiliating Genes
1lung lobe morphogenesisGO:06046310.4SHH, FOXF1
2renal system developmentGO:07200110.3SHH, FOXF1
3embryonic foregut morphogenesisGO:04861710.3SHH, FOXF1
4stem cell developmentGO:04886410.2SHH, FGF2
5cellular response to cytokine stimulusGO:07134510.1IL13, FOXF1
6neutrophil apoptotic processGO:00178110.1IL6
7embryonic digestive tract morphogenesisGO:04855710.0SHH, FOXF1
8positive regulation of chemotaxisGO:05092110.0TGFB1, CXCR3
9lung developmentGO:0303249.9FGF2, FOXF1, SHH
10positive regulation of release of sequestered calcium ion into cytosolGO:0512819.9IL13, CXCR3
11positive regulation of interleukin-17 productionGO:0327409.9TGFB1, IL18
12positive regulation of protein import into nucleusGO:0423079.8TGFB1, SHH
13cellular response to fibroblast growth factor stimulusGO:0443449.8IL8, CCL2
14epithelial cell proliferation involved in salivary gland morphogenesisGO:0606649.7IL6, SHH
15hyaluronan catabolic processGO:0302149.7FGF2, TGFB1
16negative regulation of blood vessel endothelial cell migrationGO:0435379.7FGF2, TGFB1
17cell-cell signalingGO:0072679.7SHH, CXCL5, IL18, IL13
18branching involved in salivary gland morphogenesisGO:0604459.7IL6, SHH
19regulation of vascular endothelial growth factor productionGO:0105749.7CCL2, IL6
20pancreas developmentGO:0310169.7FOXF1, SHH
21positive regulation of blood vessel endothelial cell migrationGO:0435369.6FGF2, TGFB1
22lipopolysaccharide-mediated signaling pathwayGO:0316639.6IL18, CCL2, TGFB1
23response to bacteriumGO:0096179.6CCL2, CCR4
24positive regulation of cell divisionGO:0517819.6FGF2, TGFB1, SHH
25MAPK cascadeGO:0001659.6IL18, CCL2, TGFB1
26neutrophil chemotaxisGO:0305939.5CCL2, IFNG, IL8
27cellular response to lipopolysaccharideGO:0712229.5IL8, IFNG, CCL2
28monocyte chemotaxisGO:0025489.5IL6, CCL2
29endoplasmic reticulum unfolded protein responseGO:0309689.5IL8, IFNG, CCL2
30response to glucocorticoidGO:0513849.4SFTPC, CCL2, IL6
31response to lipopolysaccharideGO:0324969.4SFTPC, IL6, IL13
32cellular response to organic cyclic compoundGO:0714079.4TGFB1, FOXF1, CCL2, IL18
33cellular component movementGO:0069289.4CXCR3, IFNG, IL8, IL13
34defense response to protozoanGO:0428329.4IL6, IFNG
35cell surface receptor signaling pathwayGO:0071669.2IFNG, CCL2, CXCR3
36response to antibioticGO:0466779.2IL6, CCR4, CCL2
37humoral immune responseGO:0069599.2IL6, IFNG, CCL2
38angiogenesisGO:0015259.2HSPG2, CXCR3, CCL2, IL18, IL8
39cell cycle arrestGO:0070509.1TGFB1, IFNG, IL8
40immune responseGO:0069559.1CXCL5, CCR4, IL18, IL8, IL13
41extracellular matrix organizationGO:0301989.0FGF2, FOXF1, SERPINH1, TGFB1, HSPG2
42agingGO:0075689.0TGFB1, CCL2, IL6
43signal transductionGO:0071658.9CXCL5, CCL2, IL8, IL13, FGF2
44chemotaxisGO:0069358.7CXCR3, CXCL5, CCL2, CCR4, IL8, FGF2
45positive regulation of transcription, DNA-templatedGO:0458938.5SHH, TGFB1, FOXF1, IL6, FGF2
46response to drugGO:0424938.5TGFB1, CCL2, IFNG, IL6
47negative regulation of cell proliferationGO:0082858.5TGFB1, IL8, IL6, FGF2
48positive regulation of cell proliferationGO:0082848.3SHH, TGFB1, CXCR3, CXCL5, IL6, FGF2
49positive regulation of transcription from RNA polymerase II promoterGO:0459447.8SHH, TGFB1, CXCR3, FOXF1, IFNG, IL6
50inflammatory responseGO:0069547.3IL13, TGFB1, CXCR3, CCL2, CCR4, IL18

Molecular functions related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine receptor activityGO:0049509.4CCR4, CXCR3
2chemokine activityGO:0080099.3CXCL5, CCL2, IL8
3growth factor activityGO:0080838.6FGF2, IL6, TGFB1
4cytokine activityGO:0051258.1FGF2, IL13, IL6, IL18, IFNG

Products for genes affiliated with Nonspecific Interstitial Pneumonia

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  • Antibodies
  • Proteins
  • Lysates

Sources for Nonspecific Interstitial Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet