NSIP
MCID: NNS002
MIFTS: 45

Nonspecific Interstitial Pneumonia (NSIP) malady

Categories: Respiratory diseases, Rare diseases

Aliases & Classifications for Nonspecific Interstitial Pneumonia

About this section
Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 45NCIt, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Nonspecific Interstitial Pneumonia:

Name: Nonspecific Interstitial Pneumonia 11 13 68
Nsip 11 54
Non-Specific Idiopathic Interstitial Pneumonia 54
 
Non-Specific Interstitial Pneumonia Nos 68
Non-Specific Interstitial Pneumonia 54

Classifications:



External Ids:

Disease Ontology11 DOID:2801
NCIt45 C35717
Orphanet54 ORPHA91364
SNOMED-CT62 129452008
UMLS via Orphanet69 C1290344
ICD10 via Orphanet31 J84.8

Summaries for Nonspecific Interstitial Pneumonia

About this section
Disease Ontology:11 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. Lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. A dry cough and shortness of breath develop over 6 to 18 months. Low-grade fever and a feeling of illness (malaise) may occur.

MalaCards based summary: Nonspecific Interstitial Pneumonia, also known as NSIP, is related to rheumatoid arthritis and surfactant metabolism dysfunction, pulmonary, 1. An important gene associated with Nonspecific Interstitial Pneumonia is SFTPC (Surfactant Protein C), and among its related pathways are Development and heterogeneity of the ILC family and OX40 Pathway. Affiliated tissues include lung, b cells and t cells, and related mouse phenotypes are neoplasm and digestive/alimentary.

Wikipedia:71 Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia. more...

Related Diseases for Nonspecific Interstitial Pneumonia

About this section

Diseases related to Nonspecific Interstitial Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 72)
idRelated DiseaseScoreTop Affiliating Genes
1rheumatoid arthritis29.1CCL2, CXCL5, IFNG, SERPINH1, TGFB1
2surfactant metabolism dysfunction, pulmonary, 110.8
3pneumonia10.8
4pulmonary fibrosis10.3
5renal hypertension10.2CXCR3, IL13
6osteochondritis dissecans10.2SERPINH1, SFTPC
7israeli tick typhus10.2IFNG, IL13
8noonan syndrome 410.2SERPINH1, TGFB1
9crustacean allergy10.2IFNG, IL13
10papillary adenocarcinoma10.2IL13, TGFB1
11acute gonococcal prostatitis10.1IFNG, IL13
12lung disease10.1
13osteodysplasty precocious of danks mayne and kozlowski10.1CXCR3, IFNG
14distal trisomy 14q10.1IFNG, TGFB1
15visceral steatosis10.1CXCR3, IL13
16behcet syndrome10.1FOXF1, SHH
17plantar wart10.1IFNG, TGFB1
18myofibroma10.1IFNG, IL13
19idiopathic interstitial pneumonia10.1
20discharging ear10.1IFNG, TGFB1
21autosomal recessive congenital methemoglobinemia10.1CXCR3, IFNG, IL13
22cyclosporiasis10.0CXCR3, IFNG
23epidermolysis bullosa10.0CXCR3, IFNG, IL13
24vascular disease10.0
25interstitial lung disease10.0
26burns10.0CXCR3, IFNG, TGFB1
27spastic diplegia10.0IFNG, IL13, TGFB1
28loiasis10.0IFNG, IL13, TGFB1
29erythematosquamous dermatosis10.0IFNG, IL13, TGFB1
30urethral intrinsic sphincter deficiency10.0CCL2, IFNG
31arthritis10.0
32connective tissue disease10.0
33chronic thromboembolic pulmonary hypertension9.9IFNG, TGFB1
34venezuelan hemorrhagic fever9.9CXCR3, IFNG
35smooth muscle tumor9.9CCL2, CXCR3, IL13
36rectum squamous cell carcinoma9.9CCL2, IL13, SFTPC
37immune-complex glomerulonephritis9.9CCL2, CXCR3, IFNG
38proximal symphalangism9.9CCL2, CXCR3, IFNG
39pulmonary hypertension9.9
40dermatomyositis9.9
41acute interstitial pneumonia9.9
42undifferentiated connective tissue disease9.9
43deafness, autosomal recessive 679.9CCL2, CXCR3, IFNG
44esophageal candidiasis9.9CCL2, CXCR3, IFNG
45bare lymphocyte syndrome, type i9.9CCL2, IFNG, IL13
46glucose intolerance9.9CCL2, IFNG
47substance-induced psychosis9.8CCL2, CXCR3, IFNG
48thymus adenosquamous carcinoma9.8CCL2, IFNG, IL13
49epithelioid type angiomyolipoma9.8CCL2, CXCR3, IFNG
50strawberry gallbladder9.8CCL2, IFNG, TGFB1

Graphical network of the top 20 diseases related to Nonspecific Interstitial Pneumonia:



Diseases related to nonspecific interstitial pneumonia

Symptoms & Phenotypes for Nonspecific Interstitial Pneumonia

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MGI Mouse Phenotypes related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.0CXCR3, IFNG, SFTPC, SHH, TGFB1
2MP:00053818.7FOXF1, IFNG, IL13, SERPINH1, SHH, TGFB1
3MP:00053858.4CXCR3, FOXF1, IFNG, SERPINH1, SFTPC, SHH
4MP:00107688.0CXCR3, FOXF1, IFNG, IL13, SERPINH1, SFTPC
5MP:00053877.9CCL2, CXCR3, IFNG, IL13, SFTPC, SHH
6MP:00053887.2CXCR3, FOXF1, IFNG, IL13, SERPINH1, SFTPC

Drugs & Therapeutics for Nonspecific Interstitial Pneumonia

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Drugs for Nonspecific Interstitial Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 32)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bosentanapproved, investigationalPhase 4104147536-97-8104865
Synonyms:
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
Bosentan
Bosentan (INN)
Bosentan [USAN:INN:BAN]
Bosentan hydrate
C27H29N5O6S
CHEBI:51450
CHEMBL957
CID104865
D07538
DB00559
 
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
PDSP1_001731
PDSP2_001714
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
bosentan
bosentanum
bosentán
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
2
NintedanibapprovedPhase 4, Phase 3116656247-17-556843413
Synonyms:
BIBF 1120
BIBF1120
 
Vargatef
methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylate
nintedanib
3Endothelin Receptor AntagonistsPhase 4218
4Antihypertensive AgentsPhase 44207
5
rituximabapprovedPhase 31692174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
6
Mycophenolic acidapprovedPhase 395224280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
7
Mycophenolate mofetilapproved, investigationalPhase 3952128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
8Vasodilator AgentsPhase 33543
9Antirheumatic AgentsPhase 310956
10Pharmaceutical SolutionsPhase 38192
11Antibiotics, AntitubercularPhase 37180
12Anti-Bacterial AgentsPhase 311226
13Immunosuppressive AgentsPhase 313086
14Sildenafil CitratePhase 3331171599-83-0
15Phosphodiesterase InhibitorsPhase 31289
16Phosphodiesterase 5 InhibitorsPhase 3589
17CitrateNutraceuticalPhase 31160
18
Citric Acidnutraceutical, vet_approvedPhase 3116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
19
Mentholapproved26062216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
20
Nitric Oxideapproved61710102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
21Peripheral Nervous System Agents23689
22Respiratory System Agents4997
23Protective Agents7443
24Antioxidants3050
25Anti-Asthmatic Agents3488
26Neurotransmitter Agents18340
27Autonomic Agents10150
28Bronchodilator Agents2965
29Endothelium-Dependent Relaxing Factors281
30Immunoglobulins6394
31Antibodies6394
32Kavanutraceutical1619000-38-8

Interventional clinical trials:

(show all 12)
idNameStatusNCT IDPhase
1Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment StudyUnknown statusNCT00637065Phase 4
2Effect of Nintedanib on Biomarkers of Extracellular Matrix Turnover in Patients With Idiopathic Pulmonary Fibrosis and Limited Forced Vital Capacity ImpairmentRecruitingNCT02788474Phase 4
368Ga-DOTA-NOC PET/CT in Patients With Idiopathic Pulmonary FibrosisTerminatedNCT01321996Phase 4
4Rituximab in Rheumatoid Arthritis Lung DiseaseCompletedNCT00578565Phase 3
5Efficacy and Safety of Nintedanib When Co-administered With Sildenafil in Idiopathic Pulmonary Fibrosis Patients With Advanced Lung Function ImpairmentRecruitingNCT02802345Phase 3
6Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung DiseasesRecruitingNCT02990286Phase 3
7Case-Control Study of Fibrotic Interstitial Lung Disease (ILD) and Cardiac Disease / Interventions.Unknown statusNCT01154998
8Prospective Observation of Fibrosis in the Lung Clinical Endpoints StudyUnknown statusNCT01110694
9Lung Diffusing Capacity for Nitric Oxide as a Marker of Fibrotic Changes in Idiopathic Interstitial PneumoniasCompletedNCT02596841
10A New Way of Looking at Your LungsCompletedNCT01949402
11Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)RecruitingNCT02827734
12Clinical Course of Interstitial Lung Diseases: European IPF Registry and BiobankRecruitingNCT02951416

Search NIH Clinical Center for Nonspecific Interstitial Pneumonia

Genetic Tests for Nonspecific Interstitial Pneumonia

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Anatomical Context for Nonspecific Interstitial Pneumonia

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MalaCards organs/tissues related to Nonspecific Interstitial Pneumonia:

36
Lung, B cells, T cells

Publications for Nonspecific Interstitial Pneumonia

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Articles related to Nonspecific Interstitial Pneumonia:

(show top 50)    (show all 137)
idTitleAuthorsYear
1
Nonspecific interstitial pneumonia preceding diagnosis of collagen vascular disease. (27492512)
2016
2
FDG-PET/CT in the prediction of pulmonary function improvement in nonspecific interstitial pneumonia. A Pilot Study. (27842667)
2016
3
Nonspecific interstitial pneumonia: time to be more specific? (27428647)
2016
4
Coexistence of Autoantibodies against the Golgi Complex and Ro52 Antigen in a Patient with Nonspecific Interstitial Pneumonia. (26831023)
2016
5
Nonspecific Interstitial Pneumonia: What Is the Optimal Approach to Management? (27231862)
2016
6
Confluent Fibrosis and Fibroblast Foci in Fibrotic Nonspecific Interstitial Pneumonia. (26864142)
2016
7
Nonspecific interstitial pneumonia overlaps organizing pneumonia in lung-dominant connective tissue disease. (26617847)
2015
8
Nonspecific interstitial pneumonia: survival is influenced by the underlying cause. (25537566)
2015
9
Ultrasound in Rheumatologic Interstitial Lung Disease: A Case Report of Nonspecific Interstitial Pneumonia in Rheumatoid Arthritis. (26240772)
2015
10
Efficacy of thrombomodulin for acute exacerbation of idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia: a nonrandomized prospective study. (26566367)
2015
11
Pulmonary Vein Stenosis Mimicking Nonspecific Interstitial Pneumonia. (26779359)
2015
12
Prognosis of nonspecific interstitial pneumonia correlates with perivascular CD4+ T lymphocyte infiltration of the lung. (26496721)
2015
13
Improvement in idiopathic nonspecific interstitial pneumonia after smoking cessation. (26029566)
2015
14
Nonspecific interstitial pneumonia: clinical associations and outcomes. (25380997)
2014
15
Pathologically proved nonspecific interstitial pneumonia: CT pattern analysis as compared with usual interstitial pneumonia CT pattern. (24661246)
2014
16
Prognostic relevance of histological variants in nonspecific interstitial pneumonia. (24621097)
2014
17
Hermansky-Pudlak syndrome with nonspecific interstitial pneumonia. (24583434)
2014
18
Nonspecific interstitial pneumonia and usual interstitial pneumonia: is differentiation possible by high-resolution computed tomography? (24480140)
2014
19
Nonspecific Interstitial pneumonia (NSIP)/ Overlap or Distinct Entity: A case report from the National Research Institute of Tuberculosis and Lung Disease (NRITLD). (24778789)
2014
20
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis. (25364525)
2014
21
Proteomic analysis in usual and nonspecific interstitial pneumonia. (24048960)
2013
22
Pathological characteristics in idiopathic nonspecific interstitial pneumonia with emphysema and pulmonary hypertension. (25473539)
2013
23
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
24
Airspace enlargement with fibrosis shows characteristic histology and immunohistology different from usual interstitial pneumonia, nonspecific interstitial pneumonia and centrilobular emphysema. (23692421)
2013
25
Quadriceps weakness contributes to exercise capacity in nonspecific interstitial pneumonia. (23312985)
2013
26
Nonspecific interstitial pneumonia. (22365250)
2012
27
Nonspecific interstitial pneumonia: a study of 6 patients with progressive disease. (22173118)
2012
28
A case of isolated IgG4-related interstitial pneumonia: a new consideration for the cause of idiopathic nonspecific interstitial pneumonia. (22796844)
2012
29
Infliximab-induced nonspecific interstitial pneumonia. (22688498)
2012
30
Idiopathic nonspecific interstitial pneumonia: changes in high-resolution computed tomography on long-term follow-up. (22446354)
2012
31
Pulmonary dendritic cell accumulation in usual interstitial pneumonia and nonspecific interstitial pneumonia. (23311128)
2012
32
Lymphatic fluctuation in the parenchymal remodeling stage of acute interstitial pneumonia, organizing pneumonia, nonspecific interstitial pneumonia and idiopathic pulmonary fibrosis. (22488224)
2012
33
Comparative manifestations and diagnostic accuracy of high-resolution computed tomography in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22759772)
2012
34
Pneumocyte biomarkers KL-6 and surfactant protein D reflect the distinct findings of high-resolution computed tomography in nonspecific interstitial pneumonia. (21555868)
2012
35
Usual interstitial pneumonia and nonspecific interstitial pneumonia: correlation between CT findings at the site of biopsy with pathological diagnoses. (22169358)
2012
36
Treatment response and long term follow-up results of nonspecific interstitial pneumonia. (22690098)
2012
37
Interstitial lung disease and antinuclear antibody: consider nonspecific interstitial pneumonia histology and newer antibodies. (22553272)
2012
38
Current status of idiopathic nonspecific interstitial pneumonia. (23001799)
2012
39
Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia. (22558525)
2012
40
Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What's the diagnosis? (23206520)
2012
41
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
42
Familial forms of nonspecific interstitial pneumonia/idiopathic pulmonary fibrosis: clinical course and genetic background. (22781209)
2012
43
Propylthiouracil-induced nonspecific interstitial pneumonia. (21362656)
2011
44
Comparison of usual interstitial pneumonia and nonspecific interstitial pneumonia: quantification of disease severity and discrimination between two diseases on HRCT using a texture-based automated system. (21603289)
2011
45
Nonspecific interstitial pneumonia: prognostic significance of high-resolution computed tomography in 59 patients. (21926853)
2011
46
Idiopathic nonspecific interstitial pneumonia: an interstitial lung disease associated with autoimmune disorders? (21273390)
2011
47
Thalidomide induced nonspecific interstitial pneumonia in patient with relapsed multiple myeloma. (21179284)
2010
48
HSP47 in lung fibroblasts is a predictor of survival in fibrotic nonspecific interstitial pneumonia. (20129768)
2010
49
Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD). (20483576)
2010
50
Nonspecific interstitial pneumonia: histologic correlation with high-resolution CT in 29 patients. (18242033)
2009

Variations for Nonspecific Interstitial Pneumonia

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Expression for genes affiliated with Nonspecific Interstitial Pneumonia

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Search GEO for disease gene expression data for Nonspecific Interstitial Pneumonia.

Pathways for genes affiliated with Nonspecific Interstitial Pneumonia

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Pathways related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

(show all 20)
idSuper pathwaysScoreTop Affiliating Genes
19.7IFNG, IL13
29.7IFNG, IL13
39.6IL13, TGFB1
4
Show member pathways
9.5IFNG, TGFB1
59.4SHH, TGFB1
69.3CXCR3, IFNG, IL13
79.2CCL2, IFNG
89.2IFNG, IL13, TGFB1
99.2IFNG, IL13, TGFB1
109.0FOXF1, SHH, TGFB1
118.8CCL2, IL13, TGFB1
128.7CCL2, CXCL5, IL13
138.7CCL2, IFNG, TGFB1
148.7CCL2, IFNG, TGFB1
15
Show member pathways
8.7CCL2, CXCL5, CXCR3
168.5CCL2, IL13, SFTPC, TGFB1
17
Show member pathways
8.2CCL2, CXCL5, IFNG, IL13
188.1CCL2, CXCL5, IFNG, TGFB1
19
Show member pathways
7.8CCL2, CXCL5, CXCR3, IL13, TGFB1
20
Show member pathways
7.3CCL2, CXCL5, CXCR3, IFNG, IL13, TGFB1

GO Terms for genes affiliated with Nonspecific Interstitial Pneumonia

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Cellular components related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.6CCL2, CXCL5, IFNG, IL13, SFTPC, SHH
2extracellular spaceGO:00056156.6CCL2, CXCL5, IFNG, IL13, SERPINH1, SFTPC

Biological processes related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

(show all 39)
idNameGO IDScoreTop Affiliating Genes
1cellular response to cytokine stimulusGO:007134510.5FOXF1, IL13
2embryonic digestive tract morphogenesisGO:004855710.3FOXF1, SHH
3embryonic foregut morphogenesisGO:004861710.3FOXF1, SHH
4epithelial tube branching involved in lung morphogenesisGO:006044110.3FOXF1, SHH
5digestive tract developmentGO:004856510.3FOXF1, TGFB1
6positive regulation of protein secretionGO:005071410.3IL13, TGFB1
7lung lobe morphogenesisGO:006046310.3FOXF1, SHH
8lung morphogenesisGO:006042510.3FOXF1, SHH
9morphogenesis of a branching structureGO:000176310.3FOXF1, TGFB1
10pancreas developmentGO:003101610.3FOXF1, SHH
11extrinsic apoptotic signaling pathwayGO:009719110.3IFNG, TGFB1
12positive regulation of mesenchymal cell proliferationGO:000205310.2FOXF1, SHH
13negative regulation of interleukin-17 productionGO:003270010.2IFNG, TGFB1
14positive regulation of protein complex assemblyGO:003133410.2IFNG, TGFB1
15renal system developmentGO:007200110.2FOXF1, SHH
16negative regulation of T cell proliferationGO:004213010.2SHH, TGFB1
17oligodendrocyte developmentGO:001400310.2SHH, TGFB1
18respiratory tube developmentGO:003032310.2FOXF1, SHH
19positive regulation of protein import into nucleusGO:004230710.1SHH, TGFB1
20protein import into nucleus, translocationGO:000006010.1IFNG, TGFB1
21movement of cell or subcellular componentGO:000692810.0CXCR3, IFNG, IL13
22trachea developmentGO:006043810.0FOXF1, SHH
23cellular response to dexamethasone stimulusGO:00715499.9CCL2, TGFB1
24lipopolysaccharide-mediated signaling pathwayGO:00316639.9CCL2, TGFB1
25positive regulation of collagen biosynthetic processGO:00329679.8CCL2, TGFB1
26heart developmentGO:00075079.8FOXF1, SHH, TGFB1
27protein kinase B signalingGO:00434919.8CCL2, TGFB1
28negative regulation of gene expressionGO:00106299.7IFNG, SHH, TGFB1
29response to progesteroneGO:00325709.6CCL2, TGFB1
30angiogenesisGO:00015259.5CCL2, CXCR3, SHH
31cellular response to organic cyclic compoundGO:00714079.5CCL2, FOXF1, TGFB1
32chemokine-mediated signaling pathwayGO:00700989.4CCL2, CXCL5, CXCR3
33chemotaxisGO:00069359.4CCL2, CXCL5, CXCR3
34response to lipopolysaccharideGO:00324969.2CCL2, CXCL5, IL13
35positive regulation of transcription, DNA-templatedGO:00458939.2FOXF1, IFNG, SHH, TGFB1
36positive regulation of cell proliferationGO:00082849.1CXCL5, IFNG, SHH, TGFB1
37vasculogenesisGO:00015709.0FOXF1, SHH, TGFB1
38immune responseGO:00069559.0CCL2, CXCL5, IFNG, IL13
39inflammatory responseGO:00069548.5CCL2, CXCL5, CXCR3, IL13, TGFB1

Molecular functions related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051257.7CCL2, CXCL5, IFNG, IL13, TGFB1

Sources for Nonspecific Interstitial Pneumonia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet