NSIP
MCID: NNS002
MIFTS: 55

Nonspecific Interstitial Pneumonia (NSIP) malady

Respiratory diseases category

Summaries for Nonspecific Interstitial Pneumonia

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8Disease Ontology, 63Wikipedia, 32MalaCards
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Disease Ontology:8 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. a dry cough and shortness of breath develop over 6 to 18 months. low-grade fever and a feeling of illness (malaise) may occur.

MalaCards: Nonspecific Interstitial Pneumonia, also known as NSIP, is related to pneumonia and pulmonary fibrosis. An important gene associated with Nonspecific Interstitial Pneumonia is FOXF1 (forkhead box F1), and among its related pathways are Rheumatoid arthritis and Malaria. The compounds pge2 and endotoxin have been mentioned in the context of this disorder. Affiliated tissues include lung, t cells and b cells, and related mouse phenotypes are vision/eye and muscle.

Wikipedia:63 Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia. more...

Aliases & Classifications for Nonspecific Interstitial Pneumonia

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Sources:
8Disease Ontology, 60UMLS, 48Orphanet, 56SNOMED-CT, 39NCIt, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Respiratory diseases


Aliases & Descriptions:

nonspecific interstitial pneumonia 8 60
nsip 8 48
non-specific idiopathic interstitial pneumonia 48
non-specific interstitial pneumonia 48


External Ids:

Disease Ontology8 DOID:2801
NCIt39 C35717
ICD10 via Orphanet26 J84.8
SNOMED-CT56 129452008
SNOMED-CT via Orphanet57 129452008
UMLS via Orphanet61 C1290344

Related Diseases for Nonspecific Interstitial Pneumonia

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Nonspecific Interstitial Pneumonia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 198)
idRelated DiseaseScoreTop Affiliating Genes
1pneumonia31.7HSPG2, CCL2, SFTPC, CXCL5, IL13, IL8
2pulmonary fibrosis31.1IL8, SERPINH1, TGFB1, IL13, CXCR3, CCR4
3idiopathic pulmonary fibrosis31.0CCR4, CCL2, SFTPC, IFNG, FGF2, CXCR3
4interstitial lung disease30.7TGFB1, IL8, SFTPC, CCL2
5vascular disease30.6FGF2, IL8, IL6
6dermatomyositis30.5HSPG2
7connective tissue disease30.4CCL2, IL6, TGFB1
8rheumatoid arthritis30.4IFNG, CCL2, CCR4, HSPG2, CXCR3, CXCL5
9arthritis30.4CCL2, IFNG, FGF2, CXCR3, CXCL5, IL13
10multiple myeloma30.2IL6
11kaposi's sarcoma30.2IL6
12bronchiolitis30.2IL8, IL13
13myeloma30.2IL6, FGF2
14hypertension30.2TGFB1, CCL2
15idiopathic interstitial pneumonia11.0
16acute interstitial pneumonia10.4
17collagen disease10.4
18interstitial emphysema10.3
19pulmonary fibrosis, familial10.3
20cryptogenic organizing pneumonia10.2
21primary biliary cirrhosis10.2
22congestive heart failure10.2
23desquamative interstitial pneumonia10.2
24pulmonary systemic sclerosis10.2
25respiratory bronchiolitis-associated interstitial lung disease10.2
26sarcoma10.2
27scleroderma10.2
28thymoma10.2
29lichen planus10.0CXCR3
30adult t-cell leukemia10.0SERPINH1
31keratoconjunctivitis10.0IL13
32lupus erythematosus10.0IL18
33atopic dermatitis10.0IL13
34nephrotic syndrome10.0IL13
35funisitis10.0SERPINH1
36esophagitis10.0IL13
37purpura10.0HSPG2
38basal cell carcinoma10.0SHH
39parkinson's disease10.0SHH
40periventricular leukomalacia10.0SERPINH1
41cholera10.0HSPG2
42colon cancer10.0HSPG2
43diabetic retinopathy10.0FGF2
44surfactant metabolism dysfunction, pulmonary, 110.0
45erythema multiforme10.0HSPG2
46vasculitis10.0CCL2
47keratitis10.0FGF2
48bladder carcinoma10.0FGF2
49moyamoya disease10.0FGF2
50hyperhomocysteinemia10.0CCL2

Graphical network of the top 20 diseases related to Nonspecific Interstitial Pneumonia:



Diseases related to nonspecific interstitial pneumonia

Clinical Features for Nonspecific Interstitial Pneumonia

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Drugs & Therapeutics for Nonspecific Interstitial Pneumonia

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Nonspecific Interstitial Pneumonia

Drug clinical trials:

Search ClinicalTrials for Nonspecific Interstitial Pneumonia

Search NIH Clinical Center for Nonspecific Interstitial Pneumonia

Search CenterWatch for Nonspecific Interstitial Pneumonia

Genetic Tests for Nonspecific Interstitial Pneumonia

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Anatomical Context for Nonspecific Interstitial Pneumonia

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32MalaCards
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MalaCards organs/tissues related to Nonspecific Interstitial Pneumonia:

32
Lung, T cells, B cells

Animal Models for Nonspecific Interstitial Pneumonia or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Nonspecific Interstitial Pneumonia:

36 (show all 16)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053919.9FGF2, SFTPC, HSPG2
2MP:00053699.4HSPG2, SHH, FGF2, TGFB1
3MP:00053909.1SERPINH1, IL6, FGF2, SHH
4MP:00053889.0TGFB1, SERPINH1, IL6, CXCR3, FOXF1, SFTPC
5MP:00107719.0IL13, IL6, TGFB1
6MP:00020068.6CCL2, SFTPC, IFNG, CXCR3, IL6, TGFB1
7MP:00053828.5TGFB1, SERPINH1, SHH, IFNG, CCL2, HSPG2
8MP:00053858.4HSPG2, CCL2, SFTPC, IFNG, FOXF1, SHH
9MP:00053767.9HSPG2, CCL2, IFNG, SHH, CXCR3, IL13
10MP:00053817.6HSPG2, CCL2, IFNG, FOXF1, SHH, IL13
11MP:00053867.5HSPG2, CCL2, SFTPC, IFNG, SHH, FGF2
12MP:00053787.2IFNG, SFTPC, CCL2, HSPG2, SHH, IL13
13MP:00053847.1HSPG2, CCL2, IFNG, SHH, FGF2, CXCR3
14MP:00053976.2SHH, IFNG, CCL2, CCR4, HSPG2, FGF2
15MP:00107686.0SHH, FOXF1, IFNG, SFTPC, CCL2, HSPG2
16MP:00053875.5SHH, IFNG, SFTPC, CCL2, CCR4, HSPG2

Publications for Nonspecific Interstitial Pneumonia

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Sources:
50PubMed
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Articles related to Nonspecific Interstitial Pneumonia:

(show top 50)    (show all 116)
idTitleAuthorsYear
1
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
2
Airspace enlargement with fibrosis shows characteristic histology and immunohistology different from usual interstitial pneumonia, nonspecific interstitial pneumonia and centrilobular emphysema. (23692421)
2013
3
Quadriceps weakness contributes to exercise capacity in nonspecific interstitial pneumonia. (23312985)
2013
4
Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia. (22558525)
2012
5
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
6
Pulmonary dendritic cell accumulation in usual interstitial pneumonia and nonspecific interstitial pneumonia. (23311128)
2012
7
Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What's the diagnosis? (23206520)
2012
8
Familial forms of nonspecific interstitial pneumonia/idiopathic pulmonary fibrosis: clinical course and genetic background. (22781209)
2012
9
A case of isolated IgG4-related interstitial pneumonia: a new consideration for the cause of idiopathic nonspecific interstitial pneumonia. (22796844)
2012
10
Idiopathic nonspecific interstitial pneumonia: changes in high-resolution computed tomography on long-term follow-up. (22446354)
2012
11
Propylthiouracil-induced nonspecific interstitial pneumonia. (21362656)
2011
12
Comparison of usual interstitial pneumonia and nonspecific interstitial pneumonia: quantification of disease severity and discrimination between two diseases on HRCT using a texture-based automated system. (21603289)
2011
13
Thalidomide induced nonspecific interstitial pneumonia in patient with relapsed multiple myeloma. (21179284)
2010
14
Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD). (20483576)
2010
15
Understanding nonspecific interstitial pneumonia: the need for a diagnostic gold standard. (19158329)
2009
16
Nonspecific interstitial pneumonia pattern as pulmonary involvement in human T-cell lymphotropic virus type 1 carriers. (19856065)
2009
17
Usual interstitial pneumonia and nonspecific interstitial pneumonia with and without concurrent emphysema: thin-section CT findings. (19221055)
2009
18
Nonspecific interstitial pneumonia associated with collagen vascular disease: analysis of CT features to distinguish the various types. (19443969)
2009
19
High serum concentrations of autoantibodies to HSP47 in nonspecific interstitial pneumonia compared with idiopathic pulmonary fibrosis. (18983650)
2008
20
Chronic hypersensitivity pneumonitis: differentiation from idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia by using thin-section CT. (18096541)
2008
21
Expression of chemokine receptors CXCR3 and CCR4 in lymphocytes of idiopathic nonspecific interstitial pneumonia. (17137778)
2007
22
Idiopathic and collagen vascular disease nonspecific interstitial pneumonia: clinical significance of remodeling process. (17294340)
2007
23
Morphologic and quantitative assessment of CD20+ B cell infiltrates in rheumatoid arthritis-associated nonspecific interstitial pneumonia and usual interstitial pneumonia. (16447242)
2006
24
Idiopathic interstitial pneumonias: usual interstitial pneumonia versus nonspecific interstitial pneumonia. (16493155)
2006
25
Pathologic subgroups of nonspecific interstitial pneumonia: differential diagnosis from other idiopathic interstitial pneumonias on high-resolution computed tomography. (16272854)
2005
26
Comparison of BALF concentrations of ENA-78 and IP10 in patients with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia. (16085216)
2005
27
Nonspecific interstitial pneumonia versus usual interstitial pneumonia: differences in the density histogram of high-resolution CT. (16012316)
2005
28
Expression of HSP47 in usual interstitial pneumonia and nonspecific interstitial pneumonia. (15955241)
2005
29
Nonspecific interstitial pneumonia, alveolar proteinosis, and abnormal proprotein trafficking resulting from a spontaneous mutation in the surfactant protein C gene. (15557112)
2005
30
Nonspecific interstitial pneumonia pattern as pulmonary involvement of rheumatoid arthritis. (15580351)
2005
31
High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia. (15481270)
2004
32
Nonspecific interstitial pneumonia and usual interstitial pneumonia with mutation in surfactant protein C in familial pulmonary fibrosis. (15133475)
2004
33
CT features of lung disease in patients with systemic sclerosis: comparison with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia. (15286324)
2004
34
A case of nonspecific interstitial pneumonia associated with thymoma. (12737285)
2003
35
Nonspecific interstitial pneumonia: correlation between thin-section CT findings and pathologic subgroups in 55 patients. (12355005)
2002
36
Survival of patients with biopsy-proven usual interstitial pneumonia and nonspecific interstitial pneumonia. (12108865)
2002
37
Nonspecific interstitial pneumonia/fibrosis completely recovered by adding cyclophosphamide to corticosteroids. (12413012)
2002
38
The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumonia. (12108451)
2002
39
An unusual case of nonspecific interstitial pneumonia treated initially with surgical resection. (12380731)
2002
40
The appearance of S-100 protein-positive dendritic cells and the distribution of lymphocyte subsets in idiopathic nonspecific interstitial pneumonia. (12412975)
2002
41
Nonspecific interstitial pneumonia-nobody said it's perfect. (11719289)
2001
42
Nonspecific interstitial pneumonia: evolving concepts. (11719646)
2001
43
Increased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumonia. (10988147)
2000
44
Idiopathic nonspecific interstitial pneumonia: prognostic significance of cellular and fibrosing patterns: survival comparison with usual interstitial pneumonia and desquamative interstitial pneumonia. (10632484)
2000
45
Nonspecific interstitial pneumonia and the other idiopathic interstitial pneumonias: classification and diagnostic criteria. (10632482)
2000
46
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis. (10471616)
1999
47
Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. (9863989)
1998
48
Nonspecific interstitial pneumonia. Individualization of a clinicopathologic entity in a series of 12 patients. (9769293)
1998
49
Nonspecific interstitial pneumonia/fibrosis: clinical manifestations, histologic and radiologic features. (8854648)
1996
50
Nonspecific interstitial pneumonia/fibrosis. Histologic features and clinical significance. (8291652)
1994

Genetic Variations for Nonspecific Interstitial Pneumonia

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Expression for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Nonspecific Interstitial Pneumonia

Search GEO for disease gene expression data for Nonspecific Interstitial Pneumonia.

Pathways for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
29KEGG, 52R&D Systems, 37NCBI BioSystems Database, 51QIAGEN, 53Reactome, 12EMD Millipore
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Pathways related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 41)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2IL18
210.2IL18
310.2IL13
410.1IL8
510.1IL8
6
Hide members
10.0IL18, IL13
7
Hide members
9.9CCL2, IL13
89.8TGFB1, SERPINH1
9
Hide members
9.8IL8, CCL2
109.4CCL2, IFNG, IL18
11
Hide members
9.4SLC7A2, SLC7A6, SLC7A1
129.4CXCL5, IL8, IL6
139.3IL18, IL8, IL6
149.3IFNG, IL18, IL6
159.2CCL2, IL8, IL6
169.2CCL2, IL6, TGFB1
17
Cytokine production by Th17 cells in CF (Mouse model)
9.2TGFB1, IL6, IL8
189.2IL6, IFNG, CCL2
199.1IL6, IL8, IFNG
20
Immune response Bacterial infections in normal airways
9.1IFNG, IL8, IL6
219.1TGFB1, IL18, IL13, IFNG
22
Hide members
9.1TGFB1, IL6, IFNG
23
Hide members
9.0IL6, IL18, IL13, IFNG
24
Hide members
9.0IL6, IL8, IL18, CCL2
25
Hide members
9.0CCR4, CXCR3, CXCL5, IL13
268.9IL6, IL8, IL18, IFNG
278.9IFNG, IL13, IL8, IL6
28
Hide members
8.8IFNG, IL18, IL6, TGFB1
298.8IFNG, IL18, IL6, TGFB1
308.7IFNG, IL8, IL6, TGFB1
318.6IFNG, IL13, IL18, IL8, IL6
328.6TGFB1, IL6, IL8, FGF2, SHH
33
Development PDGF signaling via STATs and NF-kB
Hide members
8.6CCL2, IFNG, FGF2, IL18, IL6
34
Hide members
8.6TGFB1, IL13, CXCL5, CXCR3, CCR4
35
Hide members
8.5CCR4, CCL2, CXCR3, CXCL5, IL8
368.5IL8, CXCL5, CXCR3, CCL2, CCR4
37
Hide members
8.5HSPG2, CCL2, IFNG, IL8, IL6
38
Hide members
8.4HSPG2, CCR4, FGF2, CXCR3, CXCL5, IL18
39
Hide members
8.3CCL2, IFNG, IL13, IL18, IL8, IL6
40
Hide members
8.2HSPG2, CCR4, CCL2, CXCR3, CXCL5, IL8
41
Hide members
6.8CCR4, CCL2, FGF2, CXCR3, CXCL5, IL13

Compounds for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 2BitterDB, 59Tocris Bioscience, 49PharmGKB, 24HMDB
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Compounds related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show top 50)    (show all 133)
idCompoundScoreTop Affiliating Genes
1pge24410.5TGFB1
2endotoxin4410.5CXCR3, CXCL5
3gm-csf44 2811.5IFNG
4cycloheximide4410.4IL18, HSPG2
5pentoxifylline44 1111.3IL18, IL13
6hydrocortisone44 2 59 1113.2FGF2, IL8
7indomethacin44 59 28 1113.1HSPG2
8bleomycin44 1111.0SFTPC, FGF2, IL13
9cyclosporin a44 28 5911.9SERPINH1, FGF2, IFNG
10fmlp449.8HSPG2, CXCR3, CXCL5, IL13
11herbimycin a44 5910.7HSPG2, IFNG, IL8
12prednisolone44 28 1111.5CCR4, IL13, FGF2
13mcp 1449.4IL8, CXCR3, CCL2, IL6
14mip 1alpha449.3IL6, IL8, CCL2, IL13
15dexamethasone44 49 28 1112.2SFTPC, FGF2, IL13, TGFB1, IL6
16tetracycline44 1110.2CCL2, IL18, SFTPC, TGFB1, FGF2
17bucillamine449.2IL6, FGF2, IFNG
18imiquimod44 28 59 1112.1IL6, IL8, IL18, IFNG
19rantes449.1IL6, IFNG, CXCR3, TGFB1, CXCL5
20ifn-alpha449.1IL18, IL6, IFNG, CXCR3, IL13
21infliximab44 49 1111.1IL6, IL18, CXCR3, FGF2, IFNG
22etanercept44 49 1111.1IL18, CXCR3, IFNG, IL6, IL8
23lipoteichoic acid449.0IL18, IL8, IL6, CCL2
24polymyxin b449.0CCL2, IFNG, IL8, IL6
25ccl444 2810.0IL13, CCL2, CXCR3, CXCL5, CCR4
26leukotriene b444 59 2411.0CXCL5, IL6, IL8, IL13, CCL2
27thalidomide44 49 59 1112.0IFNG, IL13, IL18, FGF2, IL6
28triptolide448.9CCL2, IFNG, IL8, IL6
29parthenolide44 29.9IL6, IL8, IFNG, CCL2
30groalpha448.8IL18, CCL2, CXCR3, IL8, IL6, CXCL5
3115-deoxy-delta-12,14-prostaglandin j2448.8CCL2, IL6, IFNG, IL8, FGF2
32tgf beta1448.7TGFB1, IL6, IL18, FGF2, IL13, CCL2
33sp 60012544 599.7CCL2, TGFB1, IL13, IL6, IL18, IL8
34il-12448.7IFNG, CCL2, IL6, IL8, IL18, IL13
35polyinosinic-polycytidylic acid448.6IL8, IL6, IL18, IFNG
36pdtc448.5IL8, IL18, CCL2, IFNG, IL6, TGFB1
37thymidine44 249.1IL6, TGFB1, CXCR3, FGF2, IL13, IL18
38il 10448.1IFNG, CXCR3, IL8, CCL2, IL18, IL6
39arginine448.0IL13, CCL2, IFNG, CXCR3, IL18, SLC7A1
40tarc448.0CCR4, CCL2, IL8, IL18, IL13, CXCL5
41actinomycin d448.0CCL2, TGFB1, IL6, IL8, FGF2, IFNG
42sb 20358044 599.0FGF2, CCL2, IFNG, IL13, IL18, TGFB1
43pd 98,059447.9HSPG2, IL18, IL8, IL6, TGFB1, CXCR3
44ly294002447.9CXCR3, TGFB1, IL8, IL18, IL13, FGF2
45simvastatin44 49 59 28 11 2412.8IL18, IFNG, CCR4, IL8, IL6, CCL2
46histamine44 28 249.8IL6, TGFB1, IL8, CXCR3, IFNG, CCL2
47ccl344 288.5IFNG, CXCL5, IL18, IL8, IL6, CXCR3
48nitric oxide44 11 249.5SERPINH1, IFNG, SLC7A2, SLC7A1, IL13, CXCR3
49retinoic acid44 248.2IL6, IFNG, IL18, FGF2, CCR4, HSPG2
50vegf446.9HSPG2, CCL2, SFTPC, IL6, TGFB1, SERPINH1

GO Terms for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources:
16Gene Ontology
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Cellular components related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098978.2IFNG, CXCR3, IL13, IL6, CCR4
2extracellular regionGO:0055766.8HSPG2, CCL2, IFNG, FGF2, CXCL5, IL13
3extracellular spaceGO:0056156.3TGFB1, HSPG2, CCL2, SFTPC, IFNG, SHH

Biological processes related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

(show all 39)
idNameGO IDScoreTop Affiliating Genes
1lung lobe morphogenesisGO:06046310.4FOXF1, SHH
2renal system developmentGO:07200110.3SHH, FOXF1
3stem cell developmentGO:04886410.3SHH, FGF2
4embryonic foregut morphogenesisGO:04861710.2SHH, FOXF1
5cellular response to mechanical stimulusGO:07126010.1IL18, IL13, SFTPC
6positive regulation of superoxide anion generationGO:03293010.1IL18, TGFB1
7response to hyperoxiaGO:05509310.0IL18, SFTPC
8epithelial cell proliferation involved in salivary gland morphogenesisGO:06066410.0SHH, IL6
9positive regulation of interleukin-17 productionGO:03274010.0TGFB1, IL18
10regulation of vascular endothelial growth factor productionGO:01057410.0CCL2, IL6
11lung developmentGO:0303249.9FOXF1, SHH, FGF2, IL18
12neutrophil apoptotic processGO:0017819.9IFNG, IL6
13positive regulation of cell divisionGO:0517819.9TGFB1, FGF2, SHH
14lipopolysaccharide-mediated signaling pathwayGO:0316639.9TGFB1, IL18, CCL2
15cellular response to tumor necrosis factorGO:0713569.9IL8, IL18, CCL2
16branching involved in salivary gland morphogenesisGO:0604459.8IL6, SHH
17angiogenesisGO:0015259.8IL18, CXCR3, CCL2, HSPG2
18cell-cell signalingGO:0072679.8IL18, IL13, CXCL5, SHH
19MAPK cascadeGO:0001659.8TGFB1, IL18, CCL2
20amino acid transportGO:0068659.8SLC7A2, SLC7A6, SLC7A1
21hyaluronan catabolic processGO:0302149.7FGF2, TGFB1
22cellular response to organic cyclic compoundGO:0714079.7TGFB1, IL18, FOXF1, CCL2
23response to glucocorticoid stimulusGO:0513849.7IL6, SFTPC, CCL2
24neutrophil chemotaxisGO:0305939.7IL8, IFNG, CCL2
25negative regulation of blood vessel endothelial cell migrationGO:0435379.6FGF2, TGFB1
26cellular component movementGO:0069289.6IL8, IL13, CXCR3, IFNG
27cellular response to lipopolysaccharideGO:0712229.6CCL2, IFNG, IL8
28positive regulation of protein import into nucleusGO:0423079.5SHH, TGFB1
29humoral immune responseGO:0069599.5IL6, IFNG, CCL2
30endoplasmic reticulum unfolded protein responseGO:0309689.5CCL2, IFNG, IL8
31extracellular matrix organizationGO:0301989.5HSPG2, FOXF1, FGF2, SERPINH1, TGFB1
32agingGO:0075689.3CCL2, IL6, TGFB1
33positive regulation of cell proliferationGO:0082849.1SHH, FGF2, CXCL5, IL6, TGFB1
34positive regulation of transcription, DNA-dependentGO:0458939.1FOXF1, SHH, FGF2, IL6, TGFB1
35chemotaxisGO:0069359.0CCR4, CCL2, FGF2, CXCR3, CXCL5
36immune responseGO:0069559.0CCR4, CXCL5, IL13, IL18, IL8
37response to drugGO:0424938.9CCL2, IFNG, IL6, TGFB1
38positive regulation of transcription from RNA polymerase II promoterGO:0459448.7IFNG, FOXF1, SHH, FGF2, IL6, TGFB1
39inflammatory responseGO:0069547.7TGFB1, CCR4, CCL2, CXCR3, IL13, IL18

Molecular functions related to Nonspecific Interstitial Pneumonia according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:0080099.6IL8, CXCL5, CCL2
2cytokine activityGO:0051258.4IL6, IL18, IL13, FGF2, IFNG

Products for genes affiliated with Nonspecific Interstitial Pneumonia

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Sources for Nonspecific Interstitial Pneumonia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet