MCID: NNS002
MIFTS: 44

Nonspecific Interstitial Pneumonia malady

Categories: Respiratory diseases, Rare diseases

Aliases & Classifications for Nonspecific Interstitial Pneumonia

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Sources:
11Disease Ontology, 13DISEASES, 30ICD10 via Orphanet, 44NCIt, 53Orphanet, 61SNOMED-CT, 67UMLS, 68UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Nonspecific Interstitial Pneumonia:

Name: Nonspecific Interstitial Pneumonia 11 13 67
Nsip 11 53
Non-Specific Idiopathic Interstitial Pneumonia 53
 
Non-Specific Interstitial Pneumonia Nos 67
Non-Specific Interstitial Pneumonia 53

Classifications:



External Ids:

Disease Ontology11 DOID:2801
NCIt44 C35717
Orphanet53 ORPHA91364
SNOMED-CT61 129452008
UMLS via Orphanet68 C1290344
ICD10 via Orphanet30 J84.8

Summaries for Nonspecific Interstitial Pneumonia

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Disease Ontology:11 An idiopathic interstitial pneumonia that occurs mainly in women, people who do not smoke, and people younger than 50 years with no known cause or risk factors. Lung biopsies may show predominantly interstitial inflammation or fibrosis or a combination of inflammation and fibrosis. A dry cough and shortness of breath develop over 6 to 18 months. Low-grade fever and a feeling of illness (malaise) may occur.

MalaCards based summary: Nonspecific Interstitial Pneumonia, also known as nsip, is related to rheumatoid arthritis and surfactant metabolism dysfunction, pulmonary, 1. An important gene associated with Nonspecific Interstitial Pneumonia is SFTPC (Surfactant Protein C), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and OX40 Pathway. Affiliated tissues include lung, b cells and t cells, and related mouse phenotypes are neoplasm and muscle.

Wikipedia:70 Non-specific interstitial pneumonia (NSIP) is a form of idiopathic interstitial pneumonia. more...

Related Diseases for Nonspecific Interstitial Pneumonia

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Diseases related to Nonspecific Interstitial Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 101)
idRelated DiseaseScoreTop Affiliating Genes
1rheumatoid arthritis28.3CCL2, CXCL5, IFNG, SERPINH1, TGFB1
2surfactant metabolism dysfunction, pulmonary, 110.8
3pneumonia10.8
4osteoarthritis10.5SERPINH1, SFTPC
5urethral villous adenoma10.5SERPINH1, SFTPC
6toxic diffuse goiter10.5CXCR3, IL13
7fibromatosis, gingival, 110.4SERPINH1, TGFB1
8burns10.4SFTPC, TGFB1
9papillary cystadenocarcinoma10.4IL13, TGFB1
10polyradiculoneuropathy10.4CXCR3, IL13
11naegeli-franceschetti-jadassohn syndrome/dermatopathia pigmentosa reticularis10.4SERPINH1, TGFB1
12loin pain hematuria syndrome10.4CXCR3, TGFB1
13salt and pepper syndrome10.4SERPINH1, TGFB1
14pulmonary fibrosis10.3
15benign mammary dysplasia10.3CCL2, CXCR3
16indian tick typhus10.3IFNG, IL13
17goat milk allergy10.3IFNG, IL13
18primary orthostatic tremor10.3CXCR3, IFNG
19hernia of ovary and fallopian tube10.3CXCR3, IFNG
20acute gonococcal salpingitis10.3IFNG, IL13
21keratopathy10.3IFNG, TGFB1
22tertiary neurosyphilis10.3IFNG, TGFB1
23orbit alveolar rhabdomyosarcoma10.3IFNG, IL13
24addison's disease10.3IFNG, TGFB1
25bolivian hemorrhagic fever10.3CXCR3, IFNG
26malignant histiocytosis10.3CXCR3, IFNG
27epidermolysis bullosa simplex superficialis10.3SERPINH1, TGFB1
28calcifying epithelial odontogenic tumor10.2IFNG, TGFB1
29orbital lymphangioma10.2IFNG, TGFB1
30twin-to-twin transfusion syndrome10.2CCL2, TGFB1
31gonococcal synovitis10.2CCL2, IFNG
32buphthalmos10.2IFNG, IL13
33hypopigmentation of eyelid10.2CCL2, TGFB1
34opiate dependence10.2CCL2, IFNG
35benign neonatal seizures10.2CCL2, TGFB1
36binocular vision disease10.1IFNG, TGFB1
37atrial tachyarrhythmia with short pr interval10.1CCL2, IFNG
38lung disease10.1
39spinal atrophy ophthalmoplegia pyramidal syndrome10.1CXCR3, IFNG
40uveitis10.1CCL2, TGFB1
41askin's tumor10.1CCL2, IFNG
42idiopathic interstitial pneumonia10.1
43oesophagostomiasis10.1CCL2, IFNG
44x-linked intellectual disability, siderius type10.1CXCR3, IFNG, IL13
45compensatory emphysema10.1CCL2, IFNG
46vascular disease10.0
47interstitial lung disease10.0
48vibrio vulnificus infection10.0CCL2, CXCR3, TGFB1
49sinusitis10.0CCL2, TGFB1
50burn scar10.0CXCR3, IFNG, TGFB1

Graphical network of the top 20 diseases related to Nonspecific Interstitial Pneumonia:



Diseases related to nonspecific interstitial pneumonia

Symptoms for Nonspecific Interstitial Pneumonia

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Drugs & Therapeutics for Nonspecific Interstitial Pneumonia

About this section

Drugs for Nonspecific Interstitial Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Bosentanapproved, investigationalPhase 4103147536-97-8104865
Synonyms:
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
Bosentan
Bosentan (INN)
Bosentan [USAN:INN:BAN]
Bosentan hydrate
C27H29N5O6S
CHEBI:51450
CHEMBL957
CID104865
D07538
DB00559
 
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
PDSP1_001731
PDSP2_001714
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
bosentan
bosentanum
bosentán
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
2Antihypertensive AgentsPhase 44095
3Endothelin Receptor AntagonistsPhase 4215
4
rituximabapprovedPhase 31654174722-31-710201696
Synonyms:
AntiCD20
IDEC-102
IDEC-C2B8
 
Ig gamma-1 chain C region
MabThera
Mabthera
Rituxan
rituximab
5
Mycophenolic acidapprovedPhase 393924280-93-1446541
Synonyms:
(e)-6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoic acid
Acide mycophenolique
Acido micofenolico
Acidum mycophenolicum
 
Melbex
Micofenolico acido
Mycophenoic acid
Mycophenolate
Mycophenolsäure
Myfortic
6
Mycophenolate mofetilapproved, investigationalPhase 3939128794-94-55281078
Synonyms:
115007-34-6
128794-94-5
140401-05-4
2-Morpholinoethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-Morpholinoethyl (e)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoate
2-morpholin-4-ylethyl (4E)-6-[4-hydroxy-7-methyl-6-(methyloxy)-3-oxo-1,3-dihydro-2-benzofuran-5-yl]-4-methylhex-4-enoate
2-morpholin-4-ylethyl (E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoate
4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl -3-oxo-5-isobenzofuranyl)-4-methyl-, 2-(4-morpholinyl)ethyl ester, (4E)
AC-1562
AC1NQXZW
AC1Q6O6X
AR-1J6939
BB_NC-2566
C07908
C23H31NO7
CHEMBL1456
CID5281078
CellCept
CellCept, RS 61443, TM-MMF, Mycophenolate mofetil
Cellcept
Cellcept (TN)
D00752
DB00688
HMS2090A03
 
HSDB 7436
I01-0898
I06-1947
LS-172272
LS-75572
ME-MPA
MMF
MMF CellCept(TM)
MolPort-000-883-800
Munoloc
Mycophenolate mofetil (JAN/USAN)
Mycophenolic acid morpholinoethyl ester
Mycophenylate mofetil
NCGC00159459-02
NCGC00159459-03
NSC724229
R-99
RS 61443
RS-61443
RS-61443-190
S1501_Selleck
TL8000648
TM-MMF
UNII-9242ECW6R0
ZINC21297660
mycophenolate mofetil
7Antirheumatic AgentsPhase 310627
8Pharmaceutical SolutionsPhase 37793
9Anti-Bacterial AgentsPhase 310884
10Antibiotics, AntitubercularPhase 36972
11Immunosuppressive AgentsPhase 312770
12
Nitric Oxideapproved59910102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
13
Mentholapproved23532216-51-516666
Synonyms:
(−
()-Menthol
(+)-Neo-menthol
(+)-p-Menthan-3-ol
(+-)-(1R*,3R*,4S*)-Menthol
(+-)-Menthol
(+/-)-Menthol
(+/-)-p-Menthan-3-ol
(-)-(1R,3R,4S)-Menthol
(-)-Menthyl alcohol
(-)-menthol
(-)-p-Menthan-3-ol
(-)-trans-p-Menthan-cis-ol
(1R)-(-)-Menthol
(1R,2S,5R)-(-)-menthol
(1R,2S,5R)-Menthol
(1R,3R,4S)-(-)-MENTHOL
(1R,3R,4S)-(-)-Menthol
(1R-(1-alpha,2-beta,5-alpha))-5-Methyl-2-(1-methylethyl)cyclohexanol
(1S, 2S, 5R)-(+)-Neomenthol
(1S,2R,5R)-(+)-Isomenthol
(1S,2R,5S)-(+)-Menthol
(1S,2R,5S)-Menthol
(1alpha,2beta,5alpha)-5-Methyl-2(1-methylethyl)cyclohexanol
(1r,2s,5r)-(-)-menthol
(L)-MENTHOL
(R)-(-)-Menthol
(r)-(-)-menthol
)-Menthol
--MENTHOL
1-Menthol
1490-04-6
15356-60-2
15356-70-4
15785_RIEDEL
15785_SIAL
19863P
2-Isopropyl-5-methylcyclohexanol
20747-49-3
2216-51-5
3-p-Menthol
4-Isopropyl-1-methylcyclohexan-3-ol
491-02-1
5-Methyl-2-(1-methylethyl)-cyclohexanol
5-Methyl-2-(1-methylethyl)cyclohexanol
5-methyl-2-(propan-2-yl)cyclohexanol
5-methyl-2-propan-2-ylcyclohexan-1-ol
551376_ALDRICH
551376_FLUKA
588733_ALDRICH
613290_ALDRICH
613290_FLUKA
63660_FLUKA
63670_ALDRICH
63670_FLUKA
63975-60-0
6C6A4A8C-A054-468C-A1F0-F29E39838CF2
89-78-1
98167-53-4
AC1L1B2E
AC1L28FR
AC1Q1NQ2
AC1Q2QQM
AI3-08161
AI3-52408
AKOS000119740
AR-1J3337
BB_NC-0057
BRN 1902288
BRN 3194263
BSPBio_003062
C00400
C10H20O
CCRIS 3728
CCRIS 375
CCRIS 4666
CCRIS 9231
CHEBI:15409
CHEBI:545611
CHEMBL256087
CHEMBL470670
CID1254
CID16666
Caswell No. 540
D-(-)-Menthol
D-p-Menthan-3-ol
D00064
D008610
D04849
D04918
DB00825
DivK1c_000820
EINECS 201-939-0
EINECS 207-724-8
EINECS 216-074-4
EINECS 218-690-9
EINECS 239-387-8
EINECS 239-388-3
EPA Pesticide Chemical Code 051601
FEMA No. 2665
Fisherman's friend lozenges
Fisherman's friend lozenges (TN)
HMS1922G13
HMS2092L14
HMS502I22
 
HSDB 5662
HSDB 593
Headache crystals
Hexahydrothymol
I06-1216
I14-7371
IDI1_000820
KBio1_000820
KBio2_000785
KBio2_003353
KBio2_005921
KBio3_002562
KBioSS_000785
L-(-)-Menthol
L-(-)-menthol
L-Menthol
L-menthol
LMPR0102090001
LS-2353
LS-57201
LS-886
LS-89531
LS-89533
Levomenthol
Levomenthol [INN:BAN]
Levomentholum
Levomentholum [INN-Latin]
Levomentol
M0321
M0545
M2772_SIAL
MENTHOL
MLS002207256
Menthacamphor
Menthol
Menthol (USP)
Menthol (VAN)
Menthol natural
Menthol natural, brazilian
Menthol racemic
Menthol racemique
Menthol racemique [French]
Menthol solution
Menthol, (1alpha,2beta,5alpha)-Isomer
Menthomenthol
Menthyl alcohol
MolPort-000-849-729
MolPort-001-793-392
NCGC00159382-02
NCGC00159382-03
NCGC00164247-01
NCGC00164247-02
NCI-C50000
NINDS_000820
NOOLISFMXDJSKH-KXUCPTDWBX
NSC 2603
NSC 62788
NSC2603
NSC62788
Neoisomenthol
Peppermint camphor
RACEMIC MENTHOL U.S.P.
Racementhol
Racementhol [INN:BAN]
Racementholum
Racementholum [INN-Latin]
Racementol
Racementol [INN-Spanish]
Racemic menthol
Robitussin Cough Drops
SDCCGMLS-0066659.P001
SMR001306785
SPBio_000869
SPECTRUM1503134
STK802468
Spectrum2_000855
Spectrum3_001561
Spectrum5_001060
Spectrum_000305
Tra-kill tracheal mite killer
U.S.P. Menthol
U.S.p. Menthol
UNII-BZ1R15MTK7
UNII-L7T10EIP3A
UNII-YS08XHA860
W266507_ALDRICH
W266523_ALDRICH
W266590_ALDRICH
WLN: L6TJ AY1&1 BQ D1
WLN: L6TJ AY1&1 DQ D1 -L
ZINC01482164
cis-1 ,3-trans-1,4-(+-)-menthol
cis-1,3-trans-1,4-(+-)-menthol
d,l-Menthol
d-Menthol
d-Neomenthol
dl-3-p-Menthanol
dl-Menthol
dl-Menthol (JP15)
l-(-)-Menthol
l-Menthol
l-Menthol (JP15)
l-Menthol (TN)
l-Menthol (natural)
nchembio862-comp1
p-Menthan-3-ol
rac-Menthol
14Peripheral Nervous System Agents22776
15Protective Agents7190
16Respiratory System Agents4818
17Vasodilator Agents3438
18Antioxidants2928
19Anti-Asthmatic Agents3369
20Neurotransmitter Agents17734
21Autonomic Agents9774
22Endothelium-Dependent Relaxing Factors272
23Bronchodilator Agents2856
24Immunoglobulins6045
25Antibodies6045
26Kavanutraceutical1489000-38-8

Interventional clinical trials:

idNameStatusNCT IDPhase
1Bosentan in Pulmonary Hypertension in Interstitial Lung Disease Treatment StudyUnknown statusNCT00637065Phase 4
268Ga-DOTA-NOC PET/CT in Patients With Idiopathic Pulmonary FibrosisTerminatedNCT01321996Phase 4
3Rituximab in Rheumatoid Arthritis Lung DiseaseCompletedNCT00578565Phase 3
4Evaluation of Efficacy and Safety of Rituximab With Mycophenolate Mofetil in Patients With Interstitial Lung DiseasesNot yet recruitingNCT02990286Phase 3
5Case-Control Study of Fibrotic Interstitial Lung Disease (ILD) and Cardiac Disease / Interventions.Unknown statusNCT01154998
6Prospective Observation of Fibrosis in the Lung Clinical Endpoints StudyUnknown statusNCT01110694
7Lung Diffusing Capacity for Nitric Oxide as a Marker of Fibrotic Changes in Idiopathic Interstitial PneumoniasCompletedNCT02596841
8Evaluation of Novel Lung Function Parameters in Patients With Interstitial Lung Disease (ILD)RecruitingNCT02827734
9Clinical Course of Interstitial Lung Diseases: European IPF Registry and BiobankRecruitingNCT02951416
10A New Way of Looking at Your LungsRecruitingNCT01949402

Search NIH Clinical Center for Nonspecific Interstitial Pneumonia

Genetic Tests for Nonspecific Interstitial Pneumonia

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Anatomical Context for Nonspecific Interstitial Pneumonia

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MalaCards organs/tissues related to Nonspecific Interstitial Pneumonia:

35
Lung, B cells, T cells

Animal Models for Nonspecific Interstitial Pneumonia or affiliated genes

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MGI Mouse Phenotypes related to Nonspecific Interstitial Pneumonia:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020069.0CXCR3, IFNG, SFTPC, SHH, TGFB1
2MP:00053698.9FOXF1, IFNG, IL13, SHH, TGFB1
3MP:00053818.7FOXF1, IFNG, IL13, SERPINH1, SHH, TGFB1
4MP:00053858.3CXCR3, FOXF1, IFNG, SERPINH1, SFTPC, SHH
5MP:00053878.2CCL2, CXCR3, IFNG, IL13, SFTPC, SHH
6MP:00107687.9CXCR3, FOXF1, IFNG, IL13, SERPINH1, SFTPC
7MP:00053887.1CXCR3, FOXF1, IFNG, IL13, SERPINH1, SFTPC

Publications for Nonspecific Interstitial Pneumonia

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Articles related to Nonspecific Interstitial Pneumonia:

(show top 50)    (show all 137)
idTitleAuthorsYear
1
Confluent Fibrosis and Fibroblast Foci in Fibrotic Nonspecific Interstitial Pneumonia. (26864142)
2016
2
Prognosis of nonspecific interstitial pneumonia correlates with perivascular CD4+ T lymphocyte infiltration of the lung. (26496721)
2015
3
Improvement in idiopathic nonspecific interstitial pneumonia after smoking cessation. (26029566)
2015
4
Hermansky-Pudlak syndrome with nonspecific interstitial pneumonia. (24583434)
2014
5
Nonspecific interstitial pneumonia and usual interstitial pneumonia: is differentiation possible by high-resolution computed tomography? (24480140)
2014
6
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis. (25364525)
2014
7
Prognostic relevance of histological variants in nonspecific interstitial pneumonia. (24621097)
2014
8
The difference of neovascularization in early intra-alveolar fibrosis between nonspecific interstitial pneumonia and usual interstitial pneumonia. (23714250)
2013
9
Proteomic analysis in usual and nonspecific interstitial pneumonia. (24048960)
2013
10
Severe pulmonary hypertension in idiopathic nonspecific interstitial pneumonia. (22558525)
2012
11
Infliximab-induced nonspecific interstitial pneumonia. (22688498)
2012
12
Usual interstitial pneumonia and nonspecific interstitial pneumonia: correlation between CT findings at the site of biopsy with pathological diagnoses. (22169358)
2012
13
Increased lymphatic vessel length is associated with the fibroblast reticulum and disease severity in usual interstitial pneumonia and nonspecific interstitial pneumonia. (22797508)
2012
14
Pulmonary dendritic cell accumulation in usual interstitial pneumonia and nonspecific interstitial pneumonia. (23311128)
2012
15
Usual interstitial pneumonia coexisted with nonspecific interstitial pneumonia, What's the diagnosis? (23206520)
2012
16
Treatment response and long term follow-up results of nonspecific interstitial pneumonia. (22690098)
2012
17
Current status of idiopathic nonspecific interstitial pneumonia. (23001799)
2012
18
Thalidomide induced nonspecific interstitial pneumonia in patient with relapsed multiple myeloma. (21179284)
2010
19
Distinct prognosis of idiopathic nonspecific interstitial pneumonia (NSIP) fulfilling criteria for undifferentiated connective tissue disease (UCTD). (20483576)
2010
20
Understanding nonspecific interstitial pneumonia: the need for a diagnostic gold standard. (19158329)
2009
21
Nonspecific interstitial pneumonia pattern as pulmonary involvement in human T-cell lymphotropic virus type 1 carriers. (19856065)
2009
22
Nonspecific interstitial pneumonia: histologic correlation with high-resolution CT in 29 patients. (18242033)
2009
23
Nonspecific interstitial pneumonia (NSIP) associated with anti-KS antibody: differentiation from idiopathic NSIP. (19652435)
2009
24
Usual interstitial pneumonia and nonspecific interstitial pneumonia with and without concurrent emphysema: thin-section CT findings. (19221055)
2009
25
Nonspecific interstitial pneumonia with abundant IgG4-positive cells infiltration, which was thought as pulmonary involvement of IgG4-related autoimmune disease. (18277032)
2008
26
Idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia should stay separate. (18448513)
2008
27
3-T MRI for differentiating inflammation- and fibrosis-predominant lesions of usual and nonspecific interstitial pneumonia: comparison study with pathologic correlation. (18356432)
2008
28
Expression of chemokine receptors CXCR3 and CCR4 in lymphocytes of idiopathic nonspecific interstitial pneumonia. (17137778)
2007
29
Volume histogram analysis for lung thin-section computed tomography: differentiation between usual interstitial pneumonia and nonspecific interstitial pneumonia. (18043360)
2007
30
Differential epithelial expression of SHH and FOXF1 in usual and nonspecific interstitial pneumonia. (16448649)
2006
31
Differential diagnosis between usual interstitial pneumonia (UIP) and nonspecific interstitial pneumonia (NSIP) assessed by high-resolution computed tomography (HRCT). (15973221)
2005
32
Nonspecific interstitial pneumonia versus usual interstitial pneumonia: differences in the density histogram of high-resolution CT. (16012316)
2005
33
Nonspecific interstitial pneumonia with poor prognosis associated with amyopathic dermatomyositis. (15497521)
2004
34
High-BAL fluid concentrations of RANTES in nonspecific interstitial pneumonia compared with usual interstitial pneumonia. (15481270)
2004
35
Nonspecific interstitial pneumonia and usual interstitial pneumonia with mutation in surfactant protein C in familial pulmonary fibrosis. (15133475)
2004
36
CT features of lung disease in patients with systemic sclerosis: comparison with idiopathic pulmonary fibrosis and nonspecific interstitial pneumonia. (15286324)
2004
37
Nonspecific interstitial pneumonia associated with polymyositis and dermatomyositis: serial high-resolution CT findings and functional correlation. (12684299)
2003
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Different cytokine profiles in usual interstitial pneumonia and nonspecific interstitial pneumonia]. (12899768)
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Nonspecific interstitial pneumonia: correlation between thin-section CT findings and pathologic subgroups in 55 patients. (12355005)
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Nonspecific interstitial pneumonia as pulmonary involvement of primary SjAPgren's syndrome. (12111081)
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The major histopathologic pattern of pulmonary fibrosis in scleroderma is nonspecific interstitial pneumonia. (12108451)
2002
42
Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparative appearances at and diagnostic accuracy of thin-section CT. (11719652)
2001
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Increased levels of interleukin-6 are associated with lymphocytosis in bronchoalveolar lavage fluids of idiopathic nonspecific interstitial pneumonia. (10988147)
2000
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Fibroblast contractility: usual interstitial pneumonia and nonspecific interstitial pneumonia. (11112149)
2000
45
Nonspecific interstitial pneumonia and the other idiopathic interstitial pneumonias: classification and diagnostic criteria. (10632482)
2000
46
A histologic pattern of nonspecific interstitial pneumonia is associated with a better prognosis than usual interstitial pneumonia in patients with cryptogenic fibrosing alveolitis. (10471616)
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47
Nonspecific interstitial pneumonia with fibrosis: serial high-resolution CT findings with functional correlation. (10511155)
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Idiopathic nonspecific interstitial pneumonia/fibrosis: comparison with idiopathic pulmonary fibrosis and BOOP. (9863989)
1998
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Nonspecific interstitial pneumonia. Individualization of a clinicopathologic entity in a series of 12 patients. (9769293)
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Nonspecific interstitial pneumonia with fibrosis: radiographic and CT findings in seven patients. (7753988)
1995

Variations for Nonspecific Interstitial Pneumonia

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Expression for genes affiliated with Nonspecific Interstitial Pneumonia

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Search GEO for disease gene expression data for Nonspecific Interstitial Pneumonia.

Pathways for genes affiliated with Nonspecific Interstitial Pneumonia

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Pathways related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathwaysScoreTop Affiliating Genes
19.8IL13, TGFB1
29.6IFNG, IL13
3
Show member pathways
9.6IFNG, TGFB1
49.2IFNG, IL13, TGFB1
59.2IFNG, IL13, TGFB1
69.2CXCR3, IFNG, IL13
79.1CCL2, IFNG, TGFB1
89.1CCL2, IFNG, TGFB1
99.0FOXF1, SHH, TGFB1
108.8CCL2, CXCL5, IL13
11
Show member pathways
8.7CCL2, CXCL5, CXCR3
12
Show member pathways
8.7CCL2, IFNG, IL13, TGFB1
138.2CCL2, CXCL5, IFNG, TGFB1
14
Show member pathways
8.0CCL2, CXCL5, CXCR3, IL13, TGFB1
15
Show member pathways
7.5CCL2, CXCL5, CXCR3, IFNG, IL13, TGFB1

GO Terms for genes affiliated with Nonspecific Interstitial Pneumonia

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Cellular components related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.3CXCR3, IFNG, IL13
2extracellular regionGO:00055766.7CCL2, CXCL5, IFNG, IL13, SFTPC, SHH
3extracellular spaceGO:00056156.6CCL2, CXCL5, IFNG, IL13, SERPINH1, SFTPC

Biological processes related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of interleukin-17 productionGO:003270010.3IFNG, TGFB1
2morphogenesis of a branching structureGO:000176310.2FOXF1, TGFB1
3protein kinase B signalingGO:004349110.2CCL2, TGFB1
4lipopolysaccharide-mediated signaling pathwayGO:003166310.2CCL2, TGFB1
5protein import into nucleus, translocationGO:000006010.2IFNG, TGFB1
6positive regulation of collagen biosynthetic processGO:003296710.1CCL2, TGFB1
7oligodendrocyte developmentGO:001400310.1SHH, TGFB1
8embryonic digestive tract morphogenesisGO:004855710.1FOXF1, SHH
9lung lobe morphogenesisGO:006046310.1FOXF1, SHH
10positive regulation of protein import into nucleusGO:004230710.1SHH, TGFB1
11respiratory tube developmentGO:003032310.1FOXF1, SHH
12lung morphogenesisGO:006042510.1FOXF1, SHH
13trachea developmentGO:006043810.1FOXF1, SHH
14positive regulation of protein secretionGO:005071410.0IL13, TGFB1
15embryonic foregut morphogenesisGO:00486179.9FOXF1, SHH
16positive regulation of mesenchymal cell proliferationGO:00020539.9FOXF1, SHH
17renal system developmentGO:00720019.9FOXF1, SHH
18pancreas developmentGO:00310169.9FOXF1, SHH
19negative regulation of T cell proliferationGO:00421309.9SHH, TGFB1
20epithelial tube branching involved in lung morphogenesisGO:00604419.6FOXF1, SHH
21cellular response to dexamethasone stimulusGO:00715499.6CCL2, TGFB1
22cellular response to organic cyclic compoundGO:00714079.5CCL2, FOXF1, TGFB1
23cellular response to cytokine stimulusGO:00713459.4FOXF1, IL13
24movement of cell or subcellular componentGO:00069289.3CXCR3, IFNG, IL13
25negative regulation of gene expressionGO:00106299.2IFNG, SHH, TGFB1
26response to lipopolysaccharideGO:00324969.2CCL2, CXCL5, IL13
27angiogenesisGO:00015259.2CCL2, CXCR3, SHH
28chemokine-mediated signaling pathwayGO:00700989.1CCL2, CXCL5, CXCR3
29chemotaxisGO:00069358.9CCL2, CXCL5, CXCR3
30positive regulation of transcription, DNA-templatedGO:00458938.8FOXF1, IFNG, SHH, TGFB1
31inflammatory responseGO:00069548.3CCL2, CXCL5, CXCR3, IL13, TGFB1
32positive regulation of cell proliferationGO:00082848.1CXCL5, IFNG, SHH, TGFB1

Molecular functions related to Nonspecific Interstitial Pneumonia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:00051258.7CCL2, IFNG, IL13, TGFB1

Sources for Nonspecific Interstitial Pneumonia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet