MCID: NNS019
MIFTS: 13

Nonsyndromic Holoprosencephaly

Categories: Neuronal diseases, Rare diseases, Fetal diseases, Endocrine diseases, Genetic diseases

Aliases & Classifications for Nonsyndromic Holoprosencephaly

MalaCards integrated aliases for Nonsyndromic Holoprosencephaly:

Name: Nonsyndromic Holoprosencephaly 24 69
Non-Syndromic, Non-Chromosomal Holoprosencephaly 24
Non-Syndromic, Non-Chromosomal Hpe 24
Holoprosencephaly Sequence 24
Isolated Holoprosencephaly 24
Nonsyndromic Hpe 24
Isolated Hpe 24

Classifications:



External Ids:

UMLS 69 C3711749

Summaries for Nonsyndromic Holoprosencephaly

Genetics Home Reference : 24 Nonsyndromic holoprosencephaly is an abnormality of brain development that also affects the head and face. Normally, the brain divides into two halves (hemispheres) during early development. Holoprosencephaly occurs when the brain fails to divide properly into the right and left hemispheres. This condition is called nonsyndromic to distinguish it from other types of holoprosencephaly caused by genetic syndromes, chromosome abnormalities, or substances that cause birth defects (teratogens). The severity of nonsyndromic holoprosencephaly varies widely among affected individuals, even within the same family.

MalaCards based summary : Nonsyndromic Holoprosencephaly, also known as non-syndromic, non-chromosomal holoprosencephaly, is related to holoprosencephaly. Affiliated tissues include brain.

Related Diseases for Nonsyndromic Holoprosencephaly

Diseases in the Holoprosencephaly family:

Holoprosencephaly 3 Holoprosencephaly 4
Holoprosencephaly 2 Holoprosencephaly 1
Holoprosencephaly 6 Holoprosencephaly 8
Holoprosencephaly 5 Holoprosencephaly 7
Holoprosencephaly 9 Holoprosencephaly 11
Nonsyndromic Holoprosencephaly

Diseases related to Nonsyndromic Holoprosencephaly via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 holoprosencephaly 10.0

Symptoms & Phenotypes for Nonsyndromic Holoprosencephaly

Drugs & Therapeutics for Nonsyndromic Holoprosencephaly

Search Clinical Trials , NIH Clinical Center for Nonsyndromic Holoprosencephaly

Genetic Tests for Nonsyndromic Holoprosencephaly

Anatomical Context for Nonsyndromic Holoprosencephaly

MalaCards organs/tissues related to Nonsyndromic Holoprosencephaly:

38
Brain

Publications for Nonsyndromic Holoprosencephaly

Articles related to Nonsyndromic Holoprosencephaly:

# Title Authors Year
1
Risk factors for nonsyndromic holoprosencephaly: a Manitoba case-control study. ( 22419615 )
2012
2
Segregation analysis in nonsyndromic holoprosencephaly. ( 9605287 )
1998

Variations for Nonsyndromic Holoprosencephaly

Expression for Nonsyndromic Holoprosencephaly

Search GEO for disease gene expression data for Nonsyndromic Holoprosencephaly.

Pathways for Nonsyndromic Holoprosencephaly

GO Terms for Nonsyndromic Holoprosencephaly

Sources for Nonsyndromic Holoprosencephaly

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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