MCID: NNN008
MIFTS: 62

Noonan Syndrome 1 malady

Genetic diseases, Rare diseases, Cardiovascular diseases, Eye diseases, Nephrological diseases, Reproductive diseases, Skin diseases, Endocrine diseases, Fetal diseases, Cancer diseases categories

Aliases & Classifications for Noonan Syndrome 1

About this section
Sources:
49OMIM, 11diseasecard, 45NIH Rare Diseases, 24GTR, 67UniProtKB/Swiss-Prot, 10Disease Ontology, 68Wikipedia, 21GeneReviews, 22GeneTests, 23Genetics Home Reference, 47Novoseek, 12DISEASES, 51Orphanet, 65UMLS, 36MeSH, 59SNOMED-CT, 42NCIt, 28ICD10 via Orphanet, 37MESH via Orphanet, 66UMLS via Orphanet, 27ICD10, 34MedGen
See all sources

Aliases & Descriptions for Noonan Syndrome 1:

Name: Noonan Syndrome 1 49 11 45 24 67
Noonan Syndrome 10 68 21 45 22 23 47 12 51 24 65 36 67
Female Pseudo-Turner Syndrome 45 23 67
Male Turner Syndrome 45 23 67
Turner's Phenotype, Karyotype Normal 10 23
Pseudo-Ullrich-Turner Syndrome 45 23
Ullrich-Noonan Syndrome 45 23
Noonan-Ehmke Syndrome 45 23
Turner-Like Syndrome 68 23
Ns1 45 67
 
Noonan Syndrome-Like Disorder with Multiple Giant Cell Lesions 67
Noonan Syndrome with Pigmented Villonodular Synovitis 67
Noonan-Like/multiple Giant Cell Lesion Syndrome 67
Turner Syndrome in Female with X Chromosome 23
Turner Phenotype with Normal Karyotype 67
Familial Turner Syndrome 23
Pterygium Colli Syndrome 67
Turner Syndrome, Male 65
Cardiomyopathies 65


Classifications:



Characteristics (Orphanet epidemiological data):

51
noonan syndrome:
Inheritance: Autosomal dominant; Prevalence: 6-9/10000 (Europe); Age of onset: Neonatal; Age of death: normal life expectancy


External Ids:

OMIM49 163950
Disease Ontology10 DOID:3490
Orphanet51 648
ICD10 via Orphanet28 Q87.1
MESH via Orphanet37 D009634
UMLS via Orphanet66 C0028326

Summaries for Noonan Syndrome 1

About this section
OMIM:49 Noonan syndrome (NS) is an autosomal dominant disorder characterized by short stature, facial dysmorphism, and a wide... (163950) more...

MalaCards based summary: Noonan Syndrome 1, also known as noonan syndrome, is related to noonan syndrome 6 and cardiofaciocutaneous syndrome, and has symptoms including abnormality of the palate, thick lower lip vermilion and malar flattening. An important gene associated with Noonan Syndrome 1 is PTPN11 (Protein Tyrosine Phosphatase, Non-Receptor Type 11), and among its related pathways are Long-term depression and Negative regulation of MAPK pathway. Affiliated tissues include heart, skin and testes, and related mouse phenotypes are no phenotypic analysis and normal.

NIH Rare Diseases:45 Noonan syndrome is a genetic disorder that causes abnormal development of multiple parts of the body. features of noonan syndrome may include a distinctive facial appearance, short stature, a broad or webbed neck, congenital heart defects, bleeding problems, skeletal malformations, and developmental delay. noonan syndrome may be caused by mutations in any one of several genes including the ptpn11, kras, raf1, sos1, nras and braf genes. it is sometimes referred to as a specific subtype based on the responsible gene in an affected person. noonan syndrome is typically inherited in an autosomal dominant manner but many cases are due to a new mutation and are not inherited from an affected parent. last updated: 6/2/2015

Genetics Home Reference:23 Noonan syndrome is a condition that affects many areas of the body. It is characterized by mildly unusual facial characteristics, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms.

UniProtKB/Swiss-Prot:67 Noonan syndrome 1: A form of Noonan syndrome, a disease characterized by short stature, facial dysmorphic features such as hypertelorism, a downward eyeslant and low-set posteriorly rotated ears, and a high incidence of congenital heart defects and hypertrophic cardiomyopathy. Other features can include a short neck with webbing or redundancy of skin, deafness, motor delay, variable intellectual deficits, multiple skeletal defects, cryptorchidism, and bleeding diathesis. Individuals with Noonan syndrome are at risk of juvenile myelomonocytic leukemia, a myeloproliferative disorder characterized by excessive production of myelomonocytic cells. Some patients with NS1 develop multiple giant cell lesions of the jaw or other bony or soft tissues, which are classified as pigmented villonodular synovitis (PVNS) when occurring in the jaw or joints.

GeneReviews summary for noonan

Related Diseases for Noonan Syndrome 1

About this section

Diseases in the Noonan Syndrome 1 family:

Noonan Syndrome 6 Noonan Syndrome 8
Noonan Syndrome 4 Noonan Syndrome 5
Noonan Syndrome 7 Noonan Syndrome 3
Noonan Syndrome 9 Noonan Syndrome 10
Noonan Syndrome 2 Rit1-Related Noonan Syndrome
Braf-Related Noonan Syndrome Kras-Related Noonan Syndrome
Map2k1-Related Noonan Syndrome Nras-Related Noonan Syndrome
Ptpn11-Related Noonan Syndrome Raf1-Related Noonan Syndrome
Sos1-Related Noonan Syndrome

Diseases related to Noonan Syndrome 1 via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 279)
idRelated DiseaseScoreTop Affiliating Genes
1noonan syndrome 631.6NRAS, PTPN11, RAF1, SOS1
2cardiofaciocutaneous syndrome31.2BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
3costello syndrome31.2KRAS, PTPN11, SOS1
4leukemia, acute myelomonocytic, somatic, somatic30.8KRAS, NRAS, PTPN11
5myelofibrosis30.6KRAS, NRAS, PTPN11
6leopard syndrome 130.6BRAF, PTPN11, RAF1
7muscular dystrophy30.5DSG2, MYH7, TNNI3, TNNT2, TPM1
8influenza11.0
9neurofibromatosis-noonan syndrome10.8
10neurofibromatosis10.7
11cardiomyopathy10.7
12noonan syndrome 310.7
13encephalitis10.7
14noonan syndrome 410.6
15noonan syndrome 510.6
16leukemia10.6
17hypertrophic cardiomyopathy10.6
18noonan syndrome 210.6
19avian influenza10.6
20noonan syndrome 1010.5
21japanese encephalitis10.5
22noonan syndrome 710.5
23noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia10.5
24noonan syndrome 810.5
25noonan syndrome 910.5
26west nile virus10.5
27tetrasomy 12p10.5KRAS, NRAS
28late-onset junctional epidermolysis bullosa10.5KRAS, NRAS
29sinoatrial node disease10.4KRAS, NRAS
30neurofibromatosis, type 110.4
31noonan syndrome with multiple lentigines10.4
32nuclear gene-encoded leigh syndrome10.4BRAF, PTPN11, RAF1
33pseudoachondroplastic dysplasia 210.4PTPN11, RAF1, SOS1
34rectosigmoid junction neoplasm10.4KRAS, NRAS
35superficial keratitis10.4PTPN11, RAF1, TNNI3
36rbp3-related retinitis pigmentosa10.4RBM20, TNNT2
37urethral syndrome10.4KRAS, NRAS
38vulvar dystrophy10.4BRAF, PTPN11, RAF1
39myh7-related familial hypertrophic cardiomyopathy10.4MYH7, TPM1
40mediastinum leiomyoma10.4KRAS, NRAS
41cancer-associated retinopathy10.4TNNI3, TNNT2
42scn5a-related brugada syndrome10.4MYH7, TPM1
43punctate acrokeratoderma freckle like pigmentation10.4BRAF, KRAS, PTPN11, RAF1
44scn5a-related romano ward syndrome10.4MYH7, TPM1
45congenital heart disease10.4
46focal palmoplantar keratoderma10.4MYH7, TNNI3, TTR
47epidermal nevus, somatic10.4KRAS, NRAS
48escobar syndrome10.4
49familial abdominal aortic aneurysm10.4BRAF, KRAS, NRAS
50ras-associated autoimmune leukoproliferative disorder10.4KRAS, NRAS

Graphical network of the top 20 diseases related to Noonan Syndrome 1:



Diseases related to noonan syndrome 1

Symptoms for Noonan Syndrome 1

About this section

Symptoms by clinical synopsis from OMIM:

163950

Clinical features from OMIM:

163950

Symptoms:

 51 (show all 57)
  • high forehead
  • triangular face
  • hypertelorism
  • downslanted palpebral fissures/anti-mongoloid slanting palpebral fissures
  • proptosis/exophthalmos
  • mid-facial hypoplasia/short/small midface
  • micrognathia/retrognathia/micrognathism/retrognathism
  • ptosis
  • anomalies of mouth, lip and philtrum
  • thick lips
  • high vaulted/narrow palate
  • low set ears/posteriorly rotated ears
  • helix/crux helix absent/abnormal/adherent/crux cymbae/posterior helix pits
  • webbed neck/pterygium colli
  • excess nuchal skin without pterygium colli
  • cystic hygroma
  • wide rib cage/thorax
  • abnormally placed nipples
  • pectus carinatum
  • pectus excavatum
  • absent/hypotonic/flaccid abdominal wall muscles
  • pulmonary valve atresia/stenosis/narrowing
  • congenital cardiac anomaly/malformation/cardiopathy
  • pulmonary artery stenosis/absence/hypoplasia of the pulmonary branches
  • late puberty/hypogonadism/hypogenitalism
  • speech troubles/aphasia/dysphasia/echolalia/mutism/logorrhea/dysprosodia
  • muscle weakness/flaccidity
  • hyperextensible joints/articular hyperlaxity
  • autosomal dominant inheritance
  • short stature/dwarfism/nanism
  • failure to thrive/difficulties for feeding in infancy/growth delay
  • strabismus/squint
  • scoliosis
  • abnormal dermatoglyphics
  • coarse/thick hair
  • low hair line (back)
  • feeding disorder/dysphagia/swallowing/sucking disorder/esophageal dyskinesia
  • hepatomegaly/liver enlargement (excluding storage disease)
  • structural and functional anomalies of the spleen
  • cardiac rhythm disorder/arrhythmia
  • anomalies of the lymphatic system
  • structural anomalies of the genital system
  • undescended/ectopic testes/cryptorchidia/unfixed testes
  • hypotonia
  • delayed bone age
  • platelets function anomaly
  • clotting/hemostasis disorders
  • hemorrhage/hemorrhagic syndrome/excessive/long-lasting bleeding
  • nystagmus
  • structural anomalies of inner ear/cochlea/vestible/semicircular canals
  • sensorineural deafness/hearing loss
  • radioulnar synostosis
  • short hand/brachydactyly
  • clinodactyly of fifth finger
  • pigmented naevi/naevus pigmentosus/lentigo
  • hypotrichosis/atrichia/atrichiasis/scalp hairlessness
  • lymphedema

HPO human phenotypes related to Noonan Syndrome 1:

(show all 93)
id Description Frequency HPO Source Accession
1 abnormality of the palate hallmark (90%) HP:0000174
2 thick lower lip vermilion hallmark (90%) HP:0000179
3 malar flattening hallmark (90%) HP:0000272
4 hypertelorism hallmark (90%) HP:0000316
5 triangular face hallmark (90%) HP:0000325
6 micrognathia hallmark (90%) HP:0000347
7 high forehead hallmark (90%) HP:0000348
8 low-set, posteriorly rotated ears hallmark (90%) HP:0000368
9 webbed neck hallmark (90%) HP:0000465
10 thickened nuchal skin fold hallmark (90%) HP:0000474
11 cystic hygroma hallmark (90%) HP:0000476
12 downslanted palpebral fissures hallmark (90%) HP:0000494
13 ptosis hallmark (90%) HP:0000508
14 proptosis hallmark (90%) HP:0000520
15 pectus excavatum hallmark (90%) HP:0000767
16 pectus carinatum hallmark (90%) HP:0000768
17 muscle weakness hallmark (90%) HP:0001324
18 joint hypermobility hallmark (90%) HP:0001382
19 abnormality of the pulmonary valve hallmark (90%) HP:0001641
20 neurological speech impairment hallmark (90%) HP:0002167
21 short stature hallmark (90%) HP:0004322
22 abnormality of the nipple hallmark (90%) HP:0004404
23 abnormality of the pulmonary artery hallmark (90%) HP:0004414
24 aplasia/hypoplasia of the abdominal wall musculature hallmark (90%) HP:0010318
25 abnormality of the helix hallmark (90%) HP:0011039
26 enlarged thorax hallmark (90%) HP:0100625
27 cryptorchidism typical (50%) HP:0000028
28 strabismus typical (50%) HP:0000486
29 muscular hypotonia typical (50%) HP:0001252
30 abnormality of the spleen typical (50%) HP:0001743
31 abnormality of thrombocytes typical (50%) HP:0001872
32 abnormality of coagulation typical (50%) HP:0001928
33 low posterior hairline typical (50%) HP:0002162
34 coarse hair typical (50%) HP:0002208
35 hepatomegaly typical (50%) HP:0002240
36 scoliosis typical (50%) HP:0002650
37 delayed skeletal maturation typical (50%) HP:0002750
38 abnormal dermatoglyphics typical (50%) HP:0007477
39 feeding difficulties in infancy typical (50%) HP:0008872
40 arrhythmia typical (50%) HP:0011675
41 intellectual disability 25% HP:0001249
42 hypogonadism occasional (7.5%) HP:0000135
43 sensorineural hearing impairment occasional (7.5%) HP:0000407
44 nystagmus occasional (7.5%) HP:0000639
45 melanocytic nevus occasional (7.5%) HP:0000995
46 lymphedema occasional (7.5%) HP:0001004
47 brachydactyly syndrome occasional (7.5%) HP:0001156
48 radioulnar synostosis occasional (7.5%) HP:0002974
49 clinodactyly of the 5th finger occasional (7.5%) HP:0004209
50 abnormal hair quantity occasional (7.5%) HP:0011362
51 autosomal dominant inheritance HP:0000006
52 cryptorchidism HP:0000028
53 high palate HP:0000218
54 epicanthus HP:0000286
55 hypertelorism HP:0000316
56 triangular face HP:0000325
57 micrognathia HP:0000347
58 low-set, posteriorly rotated ears HP:0000368
59 sensorineural hearing impairment HP:0000407
60 webbed neck HP:0000465
61 short neck HP:0000470
62 cystic hygroma HP:0000476
63 downslanted palpebral fissures HP:0000494
64 ptosis HP:0000508
65 myopia HP:0000545
66 dental malocclusion HP:0000689
67 shield chest HP:0000914
68 pectus excavatum of inferior sternum HP:0000915
69 superior pectus carinatum HP:0000917
70 lymphedema HP:0001004
71 brachydactyly syndrome HP:0001156
72 heterogeneous HP:0001425
73 failure to thrive in infancy HP:0001531
74 ventricular septal defect HP:0001629
75 atria septal defect HP:0001631
76 hypertrophic cardiomyopathy HP:0001639
77 pulmonic stenosis HP:0001642
78 patent ductus arteriosus HP:0001643
79 coarctation of aorta HP:0001680
80 abnormal bleeding HP:0001892
81 low posterior hairline HP:0002162
82 kyphoscoliosis HP:0002751
83 cubitus valgus HP:0002967
84 male infertility HP:0003251
85 short stature HP:0004322
86 reduced factor xii activity HP:0004841
87 amegakaryocytic thrombocytopenia HP:0004859
88 reduced factor xiii activity HP:0008357
89 postnatal growth retardation HP:0008897
90 radial deviation of finger HP:0009466
91 clinodactyly HP:0030084
92 neurofibrosarcoma HP:0100697
93 synovitis HP:0100769

Drugs & Therapeutics for Noonan Syndrome 1

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Drugs for Noonan Syndrome 1 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50)    (show all 293)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TrandolaprilapprovedPhase 42087679-37-65484727
Synonyms:
(2S,3aR,7aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)hexahydro-2-indolinecarboxylic acid, 1-ethyl ester
(2S,3aR,7aS)-1-(N-((1S)-1-((Ethyloxy)carbonyl)-3-phenylpropyl)-L-alanyl)octahydro-1H-indole-2-carboxylic Acid
(2S,3aR,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid
1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indol-2-carboxylic acid
87679-37-6
AC1NUNSR
BIDD:GT0804
C24H34N2O5
CCRIS 6594
CHEMBL1519
CID5484727
D00383
DB00519
FT-0082544
Gopten
I06-1849
LS-82763
 
Mavik
Mavik (TN)
NCGC00182079-03
Odric
Odrik
Preran
RU 44570
RU-44570
RU44570
Tarka
Trandolapril
Trandolapril (JAN/INN)
Trandolapril [INN:BAN]
Trandolaprilum
Trandolaprilum [Latin]
UNII-1T0N3G9CRC
Udrik
trandolapril
2
RamiprilapprovedPhase 414187333-19-55362129
Synonyms:
(2 S ,3 aS ,6 aS )-1[( S )-N-[( S )-1-Carboxy-3-phenylpropyl] alanyl] octahydrocyclopenta [ b ]pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-2-((S)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl) octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid, 1-ethyl ester
(2S,3aS,6aS)-1-((S)-N-((S)-1-Ethoxycarbonyl-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrol-2-carbonsaeure
(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(1S)-1-ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
(2S,3aS,6aS)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid (non-preferred name)
(2S-(1(R*(R*)),2alpha,3abeta,6abeta))-1-(2-((1-(Ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid.
(2S-(1(R*(r*)),2alpha,3abeta,6abeta))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydrocyclopenta(b)pyrrole-2-carboxylic acid
(2s,3as,6as)-1((s)-n-((s)-1-carboxy-3-phenylpropyl)alanyl)octahydrocyclopenta(b)pyrrole-2-carboxylic
(2s,3as,6as)-1-((s)-2-((s)-1-ethoxy-1-oxo-4-phenylbutan-2-ylamino)propanoyl)-octahydrocyclopenta[b]p
(2s,3as,6as)-1-[(s)-2-((s)-1-ethoxycarbonyl-3-phenyl-propylamino)-propionyl]-octahydro-cyclopenta[b]
126613-39-6
87333-19-5
AC-1347
AC1NSFPR
Acovil
Almirall Brand of Ramipril
Altace
Altace (TN)
Altace (tn)
Astra Brand of Ramipril
AstraZeneca Brand of Ramipril
Aventis Brand of Ramipril
Aventis Pharma Brand of Ramipril
BIDD:GT0803
BSPBio_003347
Bio-0651
C23H32N2O5
CHEBI:289203
CHEBI:8774
CHEMBL1168
CID5362129
CPD000466386
Carasel
Cardace
D00421
D017257
DB00178
Delix
HMS2051E04
HMS2090L11
HMS2093M10
HOE 498
HOE498
Hoe-498
Hoechst Brand of Ramipril
 
Hypren
Hytren
KBio2_002504
KBio2_005072
KBio2_007640
KBio3_002849
KBioGR_001858
KBioSS_002512
LS-58199
Lostapres
MLS000759523
MLS001216547
MLS001423965
MolPort-001-736-571
Monarch Brand of Ramipril
N-(1S-carboethoxy-3-phenylpropyl)-S-alanyl-cis,endo-2-azabicyclo[3.3.0]octane-3S-carboxylic Acid
NCGC00178127-01
Naprix
Pramace
Pramace (discontinued)
Promed Brand of Ramipril
Quark
R0404_SIGMA
Ramace
Ramipril
Ramipril (USP/INN)
Ramipril [USAN:INN:BAN]
Ramiprilum
Ramiprilum [Latin]
Ramipro, Tritace, Altace, Prilace, Ramipril
S1793_Selleck
SAM001246757
SAM002699899
SMR000466386
SPECTRUM1505214
STK801937
Spectrum3_001794
Spectrum4_001269
Spectrum5_001721
Spectrum_001958
Triatec
Tritace
UNII-L35JN3I7SJ
Vesdil
Zabien
[2S,3aS,6aS]-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopenta[b]pyrrole-2-carboxylic acid
[2s,3as,6as]-1-[(2s)-2-[[(1s)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydrocyclopen
ramipril
3
Amiodaroneapproved, investigationalPhase 4, Phase 31101951-25-32157
Synonyms:
(2-Butyl-3-benzofuranyl)(4-(2-(diethylamino)ethoxy)-3,5-diidophenyl)methanone
(2-butyl-1-benzofuran-3-yl)(4-{[2-(diethylamino)ethyl]oxy}-3,5-diiodophenyl)methanone
(2-butyl-1-benzofuran-3-yl)-[4-(2-diethylaminoethyloxy)-3,5-diiodophenyl]methanone
(2-butyl-1-benzofuran-3-yl){4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl}methanone
(2-butylbenzofuran-3-yl)-[4-(2-diethylaminoethoxy)-3,5-diiodo-phenyl]-methanone
(2-{4-[(2-butyl-1-benzofuran-3-yl)carbonyl]-2,6-diiodophenoxy}ethyl)diethylamine
1951-25-3
2-Butyl-3-(3,5-diiodo-4-(2-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(3,5-diiodo-4-(beta-diethylaminoethoxy)benzoyl)benzofuran
2-Butyl-3-(4'-beta-N-diethylaminoethoxy-3',5'-diiodobenzoyl)benzofuran
2-Butyl-3-[3,5-diiodo-4-(2-di
2-Butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-((2-diethylamino)ethoxy)-m,m-diiodophenyl ketone
2-Butyl-3-benzofuranyl p-[(2-diethylamino)ethoxy]-m,m-diiodophenyl ketone
2-N-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuran
5-18-02-00353 (Beilstein Handbook Reference)
AB00053422
AC1L1D1R
AC1Q2VCU
ASTA Medica Brand of Amiodarone Hydrochloride
Alphapharm Brand of Amiodarone Hydrochloride
Amidorone
Aminodarone
Amio-Aqueous IV
Amiobeta
Amiodarex
Amiodarona
Amiodarona [INN-Spanish]
Amiodarone
Amiodarone (USAN/INN)
Amiodarone Base
Amiodarone HCL
Amiodarone Hydrochloride
Amiodarone [USAN:BAN:INN]
Amiodarons
Amiodaronum
Amiodaronum [INN-Latin]
Amiohexal
Amjodaronum
Ancar
Aratac
Armstrong Brand of Amiodarone Hydrochloride
Arycor
BIDD:GT0425
BIDD:PXR0146
BPBio1_000372
BRN 1271711
BSPBio_000338
BSPBio_001574
BSPBio_002580
Berenguer Infale Brand of Amiodarone Hydrochloride
Betapharm Brand of Amiodarone Hydrochloride
Bio1_000026
Bio1_000515
Bio1_001004
Bio2_000294
Bio2_000774
Braxan
C06823
C25H29I2NO3
CAS-19774-82-4
CBiol_001740
CHEBI:2663
CHEMBL633
CID2157
Corbionax
Cordarex
Cordarone
Cordarone Intravenous
D000638
D02910
DB01118
DivK1c_000079
EINECS 217-772-1
G Gam Brand of Amiodarone Hydrochloride
 
HMS1791O16
HMS1989O16
HMS2089C07
Hexal Brand of Amiodarone Hydrochloride
IDI1_000079
IDI1_034044
KBio1_000079
KBio2_000294
KBio2_000741
KBio2_002862
KBio2_003309
KBio2_005430
KBio2_005877
KBio3_000587
KBio3_000588
KBio3_001800
KBioGR_000294
KBioGR_001859
KBioSS_000294
KBioSS_000741
Ketone, 2-butyl-3-benzofuranyl 4-(2-(diethylamino)ethoxy)-3,5-diiodophenyl
Ketone, 2-butyl-3-benzofuranyl 4-[2-(diethylamino)ethoxy]-3,5-diiodophenyl (7CI,8CI)
Kordaron
L 3428
L-3428
L001174
L3428
LS-87088
Labaz
Leurquin Brand of Amiodarone Hydrochloride
Lopac-A-8423
Lopac0_000122
MolPort-003-703-670
NCGC00015096-01
NCGC00015096-02
NCGC00015096-03
NCGC00015096-10
NCGC00024242-03
NCGC00024242-04
NCGC00024242-05
NCGC00024242-06
NCI60_041885
NINDS_000079
Nexterone
Ortacrone
Pacerone
Pharma Investi Brand of Amiodarone Hydrochloride
Prestwick0_000409
Prestwick1_000409
Prestwick2_000409
Prestwick3_000409
QTL1_000008
Rytmarone
SKF 33134-A
SKF 33134A
SPBio_001825
SPBio_002277
STK529812
STOCK1S-12240
Sanofi Winthrop Brand of Amiodarone Hydrochloride
Sedacoron
Sedacorone
Spectrum2_001813
Spectrum3_001050
Spectrum4_001190
Spectrum5_001533
Spectrum_000261
Tachydaron
UNII-N3RQ532IUT
UNM000001215003
Wyeth Brand of Amiodarone Hydrochloride
amiodarone
ethylaminoethoxy)benzoyl]benzofuran
nchembio.79-comp9
nchembio732-comp1
on
pms-Amiodarone
4
DeferiproneapprovedPhase 44930652-11-02972
Synonyms:
1,2-Dimethyl-3-hydroxypyrid-4-one
3-Hydroxy-1,2-dimethyl-4(1H)-pyridone
APO-066
CP-20
DN-180-01-AF
Deferipron
 
Deferiprona
Deferiproni
Deferipronum
Deferypron
Dimethylhydroxypyridone
Défériprone
Ferriprox
PL-1
5
Deferoxamineapproved, investigationalPhase 44470-51-92973
Synonyms:
DF B
DFO
DFOA
DFOM
Deferoxamide B
Deferoxamin
Deferoxamina
Deferoxamine
Deferoxamine B
Deferoxamine Hydrochloride
 
Deferoxamine Mesylate
Deferoxamine mesylate
Deferoxaminum
Deferrioxamine
Deferrioxamine B
Deferrioxamine b
Desferal
Desferrioxamine
Desferrioxamine B
Déferoxamine
N-Benzoylferrioxamine B
6
Lisinoprilapproved, investigationalPhase 411283915-83-75362119
Synonyms:
(2S)-1-[(2S)-6-amino-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]hexanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N(2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(2)-(1-carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N(sup 2)-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
(S)-1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
1-(N2-(1-Carboxy-3-phenylpropyl)-L-lysyl)-L-proline
1-[Nalpha-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl]-L-proline
76547-98-3
77726-95-5
83915-83-7 (Parent)
AC1NSFPF
Acerbon
Acercomp
Alapril
BB_NC-1454
BIDD:GT0755
BPBio1_000290
BRD-K67966701-335-03-5
BRN 4276619
BSPBio_000262
C21H31N3O5
CCRIS 3568
CHEBI:43755
CHEMBL1237
CID5362119
Carace
Cipral
Cipril
Coric
D08131
DB00722
DivK1c_001037
Doneka
EINECS 278-488-1
HMS1921B14
HMS2090O14
HMS2092L21
HMS503O15
I06-1895
ICI-209K
IDI1_001037
Inhibril
Inopril
KBio1_001037
KBio2_000977
KBio2_003545
KBio2_006113
KBio3_002002
KBioGR_001599
KBioSS_000977
L0220
LPR
LS-118899
Linopril
Linvas
Lipril
Lisinal
Lisinopril
Lisinopril (INN)
 
Lisinopril (anhydrous)
Lisinopril 10mg
Lisinopril 2.5mg
Lisinopril 20mg
Lisinopril 40mg
Lisinopril 5mg
Lisinopril Dihydrate
Lisinopril anhydrous
Lisinoprilum
Lisinoprilum [Latin]
Lisipril
Lisoril
Lispril
Longes
Loril
Lysinopril
MK 521
MK 522
MK-521
MLS001306436
MLS001306481
MolPort-002-507-428
N(2)-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
N-(1(S)-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N2-((S)-1-Carboxy-3-phenylpropyl)-L-lysyl-L-proline
N2-[(1S)-1-carboxy-3-phenylpropyl]-L-lysyl-L-proline
NCGC00179623-01
NINDS_001037
Noperten
Novatec
Presiten
Prestwick0_000301
Prestwick1_000301
Prestwick2_000301
Prestwick3_000301
Prinil
Prinivil
Prinzide
Renacor
SMR000544473
SPBio_001351
SPBio_002481
SPECTRUM1501217
Sinopril
Sinopryl
Spectrum2_001456
Spectrum3_000941
Spectrum4_001040
Spectrum5_000995
Spectrum_000497
TL8005499
Tensopril
Tensyn
Tersif
Vivatec
Zestoretic
Zestril
Zestril (TN)
[N2-[(S)-1-CARBOXY-3-PHENYLPROPYL]-L-LYSYL-L-PROLINE
[N2-[(S)-1-CARBOXY-3-phenylpropyl]-L-lysyl-L-proline
lisinopril
7
EplerenoneapprovedPhase 4, Phase 3, Phase 187107724-20-9150310, 443872
Synonyms:
107724-20-9
7alpha-methoxycarbonyl-3-oxo-9,11alpha-epoxy-17alpha-pregn-4-ene-21,17-carbolactone
AC-4213
AC1L9FDC
C12512
CGP-30083
CHEBI:31547
CHEBI:726453
CHEMBL1095097
CID443872
D01115
Eplerenone
 
Eplerenone (JAN/USAN/INN)
Epoxymexrenone
Inspra
Inspra (TN)
Inspra, Epoxymexrenone, CGP30083, SC-66110,Eplerenone
MolPort-003-986-216
NCGC00159559-01
NCGC00159559-02
S1707_Selleck
SC-66110
Selara
TL8000270
ZINC03985982
8
SpironolactoneapprovedPhase 4, Phase 3, Phase 21571952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
9
BisoprololapprovedPhase 4, Phase 35766722-44-92405
Synonyms:
(+-)-1-((alpha-(2-Isopropoxyethoxy)-P-tolyl)oxy)-3-(isopropylamino)-2-propanol
(+-)-1-((alpha-(2-Isopropoxyethoxy)-p-tolyl)oxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-Isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
(RS)-1-(4-(2-isopropoxyethoxymethyl)phenoxy)-3-(isopropylamino)-2-propanol
1-(propan-2-ylamino)-3-[4-(2-propan-2-yloxyethoxymethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[({2-[(1-methylethyl)oxy]ethyl}oxy)methyl]phenyl}oxy)propan-2-ol
1-{4-[(2-isopropoxyethoxy)methyl]phenoxy}-3-(isopropylamino)propan-2-ol
66722-44-9
AB00514681
AC-18540
AC1L1DLQ
AKOS005110983
ARONIS24082
BISOPROLOL
BPBio1_000373
BSPBio_000339
Bisocor
Bisoprolol
Bisoprolol (USAN/INN)
Bisoprolol Fumarate
Bisoprolol Hemifumarate
Bisoprolol [USAN:BAN:INN]
Bisoprolol fumerate
Bisoprolol hemifumarate
Bisoprololum
Bisoprololum [Latin]
C06852
C18H31NO4
CHEBI:3127
CHEMBL645
CID2405
 
CL-297939
Cardicor
Concor
Condyline
Condylox
D02342
DB00612
Detensiel
EMD-33-512
EMD-33512
Emconcor
Emcor
Euradal
I01-7040
Isoten
L000133
LS-122509
MolPort-005-937-320
Monocor
NCGC00024868-02
NCGC00024868-03
NCGC00024868-04
NCGC00024868-05
Prestwick0_000330
Prestwick1_000330
Prestwick2_000330
Prestwick3_000330
SBB065120
SPBio_002260
Soloc
Soprol
UNII-Y41JS2NL6U
Zebeta
10
CandesartanapprovedPhase 4, Phase 3, Phase 2144139481-59-72541
Synonyms:
139481-59-7
2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
2-Ethoxy-1-(P-(O-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid
2-Ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylic acid
2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
2-Ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl]}-1H-benzimidazole-7-carboxylic acid
2-Ethoxy-3-[[4-[2-(1H-tetrazol-5-yl)phenyl]phenyl] methyl]-3H-benzoimidazole-4-carboxylic acid
2-ethoxy-1-({2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl}methyl)-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylic acid
2-ethoxy-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4ethyl}-1H-benzimidazole-7-carboxylic acid
2-ethoxy-3-[[4-[2-(1h-tetrazol-5-yl)phenyl]phenyl]methyl]-3h-benzoimidazole-4-carboxylic acid
2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylic acid
2-ethoxy-7-carboxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methylbenzimidazole
AC-203
AC1L1DWT
Amias
Atacand
Atacand, Blopress, Amias, Ratacand,Candesartan
BIDD:GT0350
Blopress
Blopress (TN)
C07468
C081643
C24H20N6O3
CHEBI:216848
CHEBI:3347
 
CHEMBL1016
CID2541
CV 11974
CV-11974
CV11974
Candesartan
Candesartan (USAN/INN)
Candesartan Cilexetil
Candesartan [BAN]
Candesartan [USAN:INN]
Candesartan cilexetil
D00522
DB00796
FT-0083585
HMS2089M22
HSDB 7520
I01-0374
KS-5003
L000156
LS-32740
MolPort-003-845-570
MolPort-005-943-739
NCGC00167474-01
Ratacand
S1578_Selleck
TL8000897
UNII-S8Q36MD2XX
candesartan
11
CaptoprilapprovedPhase 42862571-86-244093
Synonyms:
(2S)-1-(3-Mercapto-2-methylpropionyl)-L-proline
(2S)-1-[(2S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(3-Mercapto-2-methyl-1-oxo-propyl)-L-proline
(S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
1-((2S)-3-Mercapto-2-methylpropionyl)-L-proline
1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
1-(D-3-Mercapto-2-methyl-1-oxopropyl)-L-proline (S,S)
1-[(2S)-2-methyl-3-sulfanylpropanoyl]-L-proline
1j37
3-Mercapto-2-methylpropionyl-proline
62571-86-2
AC-12047
AC1L2B4L
AC1Q29GZ
AC1Q5R48
Acediur
Aceplus
Acepress
Acepril
Alopresin
Apopril
Apopril (TN)
Asisten
BB_NC-2104
BIM-0050290.0001
BPBio1_000063
BRD-K54529596-001-04-0
BSPBio_000057
BSPBio_002976
C 4042
C4042_SIAL
C4042_SIGMA
C8856_SIAL
C9H15NO3S
CHEBI:3380
CHEMBL1560
CHEMBL82
CID44093
CP
CPD0-2067
CPD000059061
Capoten
Capoten (TN)
Captolane
Captopril
Captopril (JP15/USP/INN)
Captopril [USAN:INN:BAN:JAN]
Captoprilum
Captoprilum [INN-Latin]
Captopryl
Captoril
Captril
Cesplon
D-2-Methyl-3-mercaptopropanoyl-L-proline
D-3-Mercapto-2-methylpropanoyl-L-proline
D-3-Mercapto-2-methylpropionylproline
D00251
DB01197
Dilabar
DivK1c_000208
EINECS 263-607-1
EU-0100302
FT-0082749
Garranil
Garranil (discontinued)
HMS1921C12
 
HMS2089P19
HMS2092I12
HMS500K10
HSDB 6527
Hipertil
Hypertil
IDI1_000208
Isopresol
KBio1_000208
KBio2_001168
KBio2_003736
KBio2_006304
KBio3_002196
KBioGR_001321
KBioSS_001168
L-Captopril
LS-137465
Lopac-C-4042
Lopac0_000302
Lopirin
Lopirin [Switzerland]
Lopril
MCO
MLS000069484
MLS001076488
MolPort-001-794-639
N-[(S)-3-Mercapto-2-methylpropionyl]-L-proline
NCGC00015235-01
NCGC00015235-02
NCGC00023654-03
NCGC00023654-04
NCGC00023654-05
NCGC00023654-06
NCGC00023654-07
NCGC00023654-08
NCGC00023654-09
NCGC00023654-10
NINDS_000208
Prestwick3_000019
Prestwick_103
SA 333
SAM002564201
SMP1_000056
SMR000059061
SPBio_001022
SPECTRUM1500682
SQ 14,225
SQ 14225
SQ-14,225
SQ-14,534
SQ-14225
SQ-14534
ST079562
STK802012
Spectrum2_001211
Spectrum3_001388
Spectrum4_000811
Spectrum5_001587
Spectrum_000688
Tenosbon
Tensiomin
Tensobon
Tensoprel
UNII-9G64RSX1XD
UPCMLD-DP003
UPCMLD-DP003:001
X8Z
[2S]-1-[3-Mercapto-2-methylpropionyl]-L-proline
captopril
12
IronapprovedPhase 4, Phase 1, Phase 29577439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Dexiron
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
Ed-In-Sol
 
Eisen
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feraheme
Feronate
Ferretts
Ferrlecit
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Infufer
Iron
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Venofer
Vitedyn-Slo
Yieronia
fer
ferrous ascorbate
ferrous fumarate
ferrous gluconate
ferrous glycine sulfate
ferrous iron
ferrous succinate
ferrous sulfate
hierro
13
AllopurinolapprovedPhase 4, Phase 1, Phase 2125315-30-02094
Synonyms:
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidin-4-one
1,5-Dihydro-4H-pyrazolo(3,4-D)pyrimidine-4-one
184856-42-6
1H-Pyrazolo(3,4-D)pyrimidin-4-ol
22767-92-6
315-30-0
39464-14-7
4'-Hydroxypyrazolol(3,4-D)pyrimidine
4-HPP
4-Hydroxy-1H-pyrazolo(3,4-D)pyrimidine
4-Hydroxy-3,4-pyrazolopyrimidine
4-Hydroxypyrazolo(3,4-D)pyrimidine
4-Hydroxypyrazolopyrimidine
4-Hydroxypyrazolyl(3,4-D)pyrimidine
4H-Pyrazolo(3,4-D)pyrimidin-4-one
7HP
A 8003
A0907
A8003_SIGMA
AC-019
AC1L1CWL
AC1Q6FWV
AC1Q6GP7
AKOS000267490
AKOS000269759
AL-100
Adenock
Ailural
Ailurial
Allo-Puren
Allohexal
Allohexan
Alloprin
Allopur
Allopurin
Allopurinol
Allopurinol Sodium
Allopurinol(I)
Allopurinolum
Allopurinolum [INN-Latin]
Allorin
Allozym
Allpargin
Allural
Aloprim
Alopurinol
Alopurinol [INN-Spanish]
Aloral
Alositol
Aluline
Anoprolin
Anzief
Apo-Allopurinol
Apulonga
Apurin
Apurol
Atisuril
B. W. 56-158
BB_SC-5394
BIM-0061756.0001
BSPBio_001798
BW 56-158
BW 56158
BW-56-158
Bio-0799
Bleminol
Bloxanth
C5H4N4O
CCRIS 626
CHEBI:40279
CHEBI:495607
CHEMBL1467
CID2094
CPD-9024
CPD000059083
Caplenal
Capurate
Cellidrin
Cosuric
D000493
DB00437
Dabrosin
Dabroson
DivK1c_000685
Dura Al
EINECS 206-250-9
EN000932
EU-0100102
Embarin
Epidropal
Epuric
Foligan
Geapur
Gichtex
Gotax
HMS1920A15
HMS2091G15
HMS502C07
HPP
 
HSDB 3004
Hamarin
Hexanuret
I03-0052
IDI1_000685
Jenapurinol
Jsp005881
KBio1_000685
KBio2_000386
KBio2_002954
KBio2_005522
KBio3_001298
KBioGR_000550
KBioSS_000386
Ketanrift
Ketobun-A
LS-1180
Ledopur
Lopac-A-8003
Lopac0_000102
Lopurin
Lysuron
MLS000069453
MLS001148183
Milurit
Milurite
Miniplanor
MolPort-000-141-383
MolPort-000-870-337
MolPort-004-758-159
MolPort-004-758-166
MolPort-004-758-167
MolPort-004-758-643
Monarch
NCGC00015094-01
NCGC00015094-03
NCGC00015094-06
NCGC00091134-01
NCGC00091134-02
NCGC00091134-03
NCGC00094580-01
NCGC00094580-02
NCIOpen2_001825
NINDS_000685
NSC 101655
NSC 1390
NSC-1390
NSC101655
NSC1390
Nektrohan
Novopurol
Pan Quimica
Prestwick_511
Progout
Pureduct
Purinol
Quimica, Pan
Remid
Riball
Rimapurinol
Roucol
S1630_Selleck
SAM002554884
SMR000059083
SPBio_000056
SPECTRUM1500108
STK378584
STK711106
Sigapurol
Spectrum2_000098
Spectrum3_000289
Spectrum4_000135
Spectrum5_000768
Spectrum_000026
Suspendol
Takanarumin
Tipuric
UNII-63CZ7GJN5I
Urbol
Uribenz
Uricemil
Uridocid
Uriprim
Uripurinol
Uritas
Urobenyl
Urolit
Urosin
Urtias
Urtias 100
Xanthomax
Xanturat
Xanturic
Zygout
Zyloprim
Zyloprim (tn)
Zyloric
allopurinol
nchembio.92-comp3
nchembio732-comp4
14
AmlodipineapprovedPhase 443188150-42-92162
Synonyms:
()-Amlodipine
(RS)-3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
-3-(ethoxycarbonyl)-5-(methoxycarbonyl)-6-methyl-1,4-dihydropyridine
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)
3,5-Pyridinedicarboxylic acid, 2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
3-Ethyl 5-methylester, (±)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxy)methyl)-4-(2-chlorphenyl)-1,4-dihydro-6-methyl-3,5-pyridindicarboxylat
3-Ethyl-5-methyl ( -)-2-((2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(O-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (+-)-2-(2-aminoethoxymethyl)-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-Ethyl-5-methyl (.+/-.)-2-[(2-aminoethoxy)methyl]-4-(o-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate
3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
3-ethyl 5-methyl 2-{[(2-aminoethyl)oxy]methyl}-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
88150-42-9
88150-47-4 (maleate (1:1))
AC-4535
AC1L1D26
AC1Q32ZS
AMLODIPINE BASE
AMVAZ
Ambap88150-42-9
Amlocard
Amlodipine
Amlodipine (INN)
Amlodipine Benzenesulfonate
Amlodipine Besilate
Amlodipine Besylate
Amlodipine Free Base
Amlodipine Maleate
Amlodipine [INN:BAN]
Amlodipine besilate
Amlodipine besylate
Amlodipine free base
Amlodipino
Amlodipino [Spanish]
Amlodipinum
Amlodipinum [Latin]
Amlodis
Amlopres
Amlor
 
Amvaz
BIDD:GT0810
BRD-A22032524-074-02-4
BRD-A22032524-074-03-2
BSPBio_002727
C06825
CHEBI:2668
CHEMBL1491
CID2162
CPD000469198
Coroval
D07450
DB00381
HMS2052N03
HMS2089H07
I14-0798
Intervask
Istin
KBio3_001947
KBioGR_001643
LS-131183
Lipinox
Lotrel
MLS001401409
MolPort-001-792-963
NCGC00165957-01
NCGC00165957-02
NCGC00165957-03
Norvasc
Norvasc (TN)
Pelmec
R,S)-Amlodipine
Racemic Amlodipine
SAM001246705
SMR000469198
SPBio_000351
Spectrum2_000486
Spectrum3_001004
Spectrum4_001132
Spectrum5_001550
UK-4834011
UNII-1J444QC288
amlodipine
15
DobutamineapprovedPhase 4, Phase 3, Phase 1, Phase 29934368-04-236811
Synonyms:
(+-)-4-(2-((3-(P-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
(+-)-4-(2-((3-(p-Hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol
3,4-Dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine
34368-04-2
34368-04-2 (Parent)
4-(2-{[3-(4-hydroxyphenyl)-1-methylpropyl]amino}ethyl)benzene-1,2-diol
4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol
4-[2-[4-(4-hydroxyphenyl)butan-2-ylamino]ethyl]benzene-1,2-diol
4-{2-[3-(4-hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
52663-81-7 (hydrochloride)
74753-15-4
74753-15-4 (hydrobromide)
AC1L1WFF
AC1Q7AD1
BPBio1_000489
BRD-A78322124-003-03-3
BSPBio_000443
C06967
CHEBI:4670
CHEMBL926
CID36811
D03879
DB00841
DL-Dobutamine
DL-dobutamine
Dobutamin
Dobutamina
Dobutamina [INN-Spanish]
Dobutamine
Dobutamine (USP/INN)
Dobutamine Hcl
Dobutamine Hcl in Dextrose 5%
Dobutamine Hydrochloride
 
Dobutamine Tartrate (1:1), (S-(R*,R*))-Isomer
Dobutamine [USAN:BAN:INN]
Dobutamine [USAN]
Dobutamine [Usan:Ban:Inn]
Dobutamine [Usan]
Dobutamine hydrobromide
Dobutamine hydrochloride
Dobutaminum
Dobutaminum [INN-Latin]
Dobutrex
EINECS 277-982-4
HMS2089K05
Inotrex
L001157
LS-174467
LY 81929
Lilly 81929
Lopac0_000365
NCGC00015321-05
NCGC00024629-02
NCGC00024629-03
Prestwick0_000352
Prestwick1_000352
Prestwick2_000352
Prestwick3_000352
Racemic-Dobutamine
Racemic-dobutamine
SPBio_002364
UNII-0WR771DJXV
UNII-3S12J47372
dobutamine
dobutamine(usp)
rac-Dobutamine
rac-dobutamine
racemic-Dobutamine
16
Nitric OxideapprovedPhase 4, Phase 3, Phase 254010102-43-9145068
Synonyms:
(.)NO
(NO)(.)
10102-43-9
14332-28-6
295566_ALDRICH
51005-20-0
51005-21-1
53851-19-7
90452-29-2
AC1L1ADQ
AC1L3QHF
AC1Q6QZ0
AR-1K7463
Bioxyde d'azote
Bioxyde d'azote [French]
C00533
CCRIS 4319
CHEMBL1200689
CHEMBL1234765
CID145068
CID945
D00074
D009569
DB00435
EDRF
EINECS 233-271-0
Endogenous Nitrate Vasodilator
Endothelium-Derived Nitric Oxide
HNO
HSDB 1246
INOmax
INOmax (TN)
Inomax
LS-192158
LS-7547
MolPort-003-929-452
Mononitrogen monoxide
Monoxide, Mononitrogen
Monoxide, Nitrogen
Monoxido de nitrogeno
Monoxyde d'azote
NITRIC-OXIDE
NO
NO(.)
Nitrate Vasodilator, Endogenous
Nitric Oxide, Endothelium Derived
 
Nitric Oxide, Endothelium-Derived
Nitric oxide
Nitric oxide (JAN)
Nitric oxide 10% by volume or more
Nitric oxide trimer
Nitric oxide, compressed [UN1660] [Poison gas]
Nitric oxide, compressed [UN1660] [Poison gas]
Nitrogen monoxide
Nitrogen oxide
Nitrogen oxide (NO)
Nitrogen protoxide
Nitrosyl
Nitrosyl hydride
Nitrosyl hydride ((NO)H)
Nitrosyl radical
Nitroxide radical
Nitroxyl
OHM 11771
Oxide, Nitric
Oxido de nitrogeno(ii)
Oxido nitrico
Oxyde azotique
Oxyde nitrique
Oxyde nitrique [French]
RCRA waste no. P076
Stickmonoxyd
Stickmonoxyd [German]
Stickstoff(II)-oxid
Stickstoff(ii)-oxid
Stickstoffmonoxid
UN 1660
UN1660
UNII-31C4KY9ESH
Vasodilator, Endogenous Nitrate
[NO]
endothelium-derived relaxing factor
monoxido de nitrogeno
monoxyde d'azote
nitric oxide
nitrogen monooxide
nitrogen monoxide
nitrosyl
oxido de nitrogeno(II)
oxido nitrico
oxidonitrogen(.)
oxoazanyl
oxyde azotique
17
PrednisoneapprovedPhase 4, Phase 3, Phase 2, Phase 1120853-03-25865
Synonyms:
(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione
(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione
.delta. E
.delta.(sup1)-Cortisone
.delta.-Cortelan
.delta.-Cortisone
.delta.-Cortone
.delta.-E
.delta.1-Cortisone
.delta.1-Dehydrocortisone
.delta.sone
1,2-Dehydrocortisone
1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione
1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione
1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione
1-Cortisone
1-Dehydrocortisone
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione
17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione
53-03-2
68-59-7
81552_FLUKA
AC-11112
AC1L1LB2
AC1Q29EZ
ACon0_000082
ACon1_000297
AI3-52939
Adasone
Ancortone
Apo-Prednisone
Apo-prednisone
BPBio1_000323
BRD-K85883481-001-04-2
BSPBio_000293
Betapar
Bicortone
Bio-0649
C07370
C21H26O5
CCRIS 2646
CHEBI:8382
CHEMBL635
CID5865
CPD001227202
Cartancyl
Colisone
Cortan
Cortancyl
Cortidelt
Cotone
DB00635
Dacorten
Dacortin
Decortancyl
Decortin
Decortisyl
Dehydrocortisone
Dekortin
Delcortin
Dellacort
Dellacort A
Delta Cortelan
Delta E
Delta E.
Delta-Cortelan
Delta-Dome
Delta-cortelan
Delta-cortisone
Delta-cortone
Delta-dome
Deltacortene
Deltacortisone
Deltacortone
Deltasone
Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone
Deltison
Deltisona
Deltisone
Deltra
Di-Adreson
Diadreson
EINECS 200-160-3
Econosone
Encorton
Encortone
Enkortolon
Enkorton
Fernisone
Fiasone
HMS1568O15
HMS2090J13
HSDB 3168
Hostacortin
In-Sone
Incocortyl
Juvason
 
Kortancyl
LMST02030180
LS-1325
Liquid Pred
Lisacort
Lodotra
MEGxm0_000443
MLS001061265
MLS001304073
MLS001335907
MLS001335908
MLS002154191
MLS002207083
Me-Korti
Metacortandracin
Meticorten
Meticorten (Veterinary)
Metrevet (Veterinary)
MolPort-001-740-041
NCGC00090766-01
NCGC00090766-02
NCGC00090766-03
NCI-C04897
NCI60_000008
NSC 10023
NSC10023
Nisona
Nizon
Novoprednisone
Nurison
Orasone
Origen Prednisone
P1276
P6254_SIGMA
PRD
Panafcort
Panasol
Paracort
Parmenison
Pehacort
Perrigo Prednisone
Precort
Predeltin
Prednicen-M
Prednicorm
Prednicort
Prednicot
Prednidib
Prednilonga
Prednison
Prednisona
Prednisona [INN-Spanish]
Prednisone
Prednisone Intensol
Prednisone [INN:BAN]
Prednisonum
Prednisonum [INN-Latin]
Prednitone
Prednizon
Prednovister
Presone
Prestwick0_000077
Prestwick1_000077
Prestwick2_000077
Prestwick3_000077
Prestwick_405
Pronison
Pronisone
Rayos
Rectodelt
Retrocortine
S1622_Selleck
SAM002264641
SK-Prednisone
SMR000718760
SMR001227202
SPBio_002214
Servisone
Sone
Sterapred
Supercortil
U 6020
UNII-VB0R961HZT
Ultracorten
Ultracortene
WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ
Winpred
Wojtab
ZINC03875357
Zenadrid
Zenadrid (veterinary)
Zenadrid [veterinary]
delta cortelan
delta(sup 1)-Cortisone
delta(sup 1)-Dehydrocortisone
delta-1-Cortisone
delta-1-Dehydrocortisone
delta-Cortisone
delta-Cortone
18
CilostazolapprovedPhase 49873963-72-12754
Synonyms:
3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
3,4-dihydro-6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril
6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone
6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one
6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
73963-72-1
89332-50-3
AC-4334
AC1L1EE2
BRD-K67017579-001-04-2
BRD-K67017579-001-05-9
BRD-K67017579-001-07-5
BRD-K67017579-001-13-3
BRN 3632107
BSPBio_002759
C 0737
C045645
C0737_SIGMA
C20H27N5O2
CHEBI:31401
CHEMBL799
CID2754
CL23867
CPD000058428
Cilostazol
Cilostazol (JP15/USAN/INN)
Cilostazol [INN:JAN]
Cilostazole
Cilostazolum
Cilostazolum [INN-Latin]
D01896
DB01166
EU-0100218
HMS1922N15
HMS2093M14
KBio3_002259
KBioGR_001184
 
LS-142693
Lopac-C-0737
Lopac0_000218
MLS000028470
MLS000758281
MLS000759507
MLS001076067
MLS002153891
MolPort-001-758-007
NCGC00015207-01
NCGC00015207-02
NCGC00015207-06
NCGC00015207-10
NCGC00022153-02
NCGC00022153-04
NCGC00022153-05
NCGC00022153-06
NCGC00022153-07
OPC 13013
OPC 21
OPC-13013
OPC-21
Otsuka brand of cilostazol
Pletaal
Pletal
Pletal (TN)
Pletal, Cilostazol
S1294_Selleck
SAM001246734
SAM001247085
SMR000058428
SPBio_001256
SPECTRUM1505230
Spectrum2_001118
Spectrum3_001170
Spectrum4_000772
Spectrum5_001762
TL8005113
Tocris-1692
UNII-N7Z035406B
ZINC01552174
cilostazol
19
IsofluraneapprovedPhase 48026675-46-73763
Synonyms:
1-Chloro-2,2,2-trifluoroethyl difluoromethyl ether
1-chloro-2,2,2-Trifluoroethyl difluoromethyl ether
2-Chloro-2-(difluoromethoxy)-1,1,1-trifluoroethane
2-chloro-2-difluoromethoxy-1,1,1-trifluoroethane
26675-46-7
AC-154802
AC1L1GNN
AErrane (Veterinary)
Aerrane
BRN 1852087
C07518
CCRIS 3043
CHEBI:6015
CHEMBL1256
CID3763
Compound 469
D00545
D007530
DB00753
EINECS 247-897-7
Ethane
Ether, 1-chloro-2,2,2-trifluoroethyl difluoromethyl
 
Forane
Forane (TN)
Forene
I14-1303
IsoFlo
Isoflurane
Isoflurane (JP15/USP/INN)
Isoflurane [Anaesthetics, volatile]
Isoflurane [USAN:BAN:INN:JAN]
Isoflurane [USAN:INN:BAN:JAN]
Isoflurane [Usan:Ban:Inn:Jan]
Isoflurano
Isoflurano [INN-Spanish]
Isofluranum
Isofluranum [INN-Latin]
Jsp005223
LS-7462
MolPort-000-153-606
NCGC00181037-01
R-E 235dal
ST51041445
Terrell
UNII-CYS9AKD70P
isoflurane
20
Sildenafilapproved, investigationalPhase 4296139755-83-25212
Synonyms:
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-D)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(4,7-Dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine
1-((3-(6,7-dihydro-1-methyl-7-oxo-3-propyl-1H-pyrazolo(4,3-d)pyrimidin-5-yl)-4-ethoxyphenyl)sulfonyl)-4-methylpiperazine citrate
139755-83-2
171599-83-0 (citrate)
1udt
1xos
2h42
5-(2-ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl)-1-methyl-3-propyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one (Sildenafil or Viagra)
5-[2-Ethoxy-5-(4-methyl-piperazine-1-sulfonyl)-phenyl]-1-methyl-3-propyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one(Sildenafil)
5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one
5-{2-(ethyloxy)-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
5-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one
AC-938
AC1L1JUI
Ambap139755-83-2
Aphrodil
Aphrodil (TN)
BAS 04213629
BIDD:GT0352
BRD-K79759585-001-02-1
BSPBio_003424
C07259
C22H30N6O4S
CHEBI:9139
CHEMBL192
CID5212
Caverta
D08514
DB00203
DivK1c_006894
HMS1684K08
HMS1922B19
HMS2089M12
HMS2093O17
HSDB 7305
 
I06-0023
Jsp002373
KBio1_001838
KBio2_002035
KBio2_004603
KBio2_007171
KBio3_002927
KBioGR_001052
KBioSS_002035
LS-111655
MLS001240224
MLS001304737
MolPort-001-995-394
MolPort-002-885-861
NCGC00095099-01
NCGC00095099-02
NCGC00159496-02
Revatio
SMR000752512
SPBio_001775
SPECTRUM1504099
Sildenafil
Sildenafil (INN)
Sildenafil Citrate
Sildenafil Viagra
Sildenafil [INN:BAN]
Sildenafil citrate
SpecPlus_000798
Spectrum2_001648
Spectrum3_001892
Spectrum4_000586
Spectrum5_001508
Spectrum_001555
UK-92,480-10
UK-92480
UNII-3M7OB98Y7H
VIA
Viagra
sildenafil
21
DexmedetomidineapprovedPhase 4420113775-47-668602, 5311068, 56032
Synonyms:
(+)-4-((S)-alpha,2,3-Trimethylbenzyl)imidazole
(+)-4-((S)-alpha,2,3-trimethylbenzyl)imidazole
(+)-medetomidine
(S)-medetomidine
113775-47-6
4-[(1S)-1-(2,3-Dimethylphenyl)ethyl]-1H-imidazole
4-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
AC1NSJXT
C07450
CHEBI:4466
CHEMBL778
CID5311068
D00514
DEXMEDETOMIDINE
Dexdor (T)
 
Dexmedetomidin
Dexmedetomidina
Dexmedetomidine
Dexmedetomidine (USAN/INN)
Dexmedetomidine Hydrochloride
Dexmedetomidinum
Dexmédétomidine
MPV 1440
MPV-1440
Medetomidina [Spanish]
Medetomidine
Medetomidinum [Latin]
NCGC00025347-01
PRECEDEX
Precedex
Precedex (TN)
Tocris-2023
ZINC04632106
22
RemifentanilapprovedPhase 4386132875-61-760815
Synonyms:
1-Piperidinepropanoic acid, 4-(methoxy-carbonyl)-4-((1-oxopropyl)phenylamino)-, methyl ester
132539-07-2 (mono-hydrochloride)
132875-61-7
3-(4-methoxycarbonyl-4-((1-oxopropyl)phenylamino)-1-piperidine)propanoic acid methyl ester
4-carboxy-4-(n-phenylpropionamido)-1-piperidinepropionic acid dimethyl ester
AC1L1TZ8
AC1Q5ZGR
BIDD:GT0029
C08021
CHEBI:8802
CHEMBL1005
CID60815
D08473
DB00899
 
DEA No. 9739
GI 87084B
GI 87084X
GI87084B
L001266
LS-115982
MolPort-004-286-006
REMIFENTANIL
Remifentanil (INN)
Remifentanil [INN:BAN]
Remifentanyl
UNII-P10582JYYK
Ultiva
Ultiva (TN)
methyl 1-(3-methoxy-3-oxopropyl)-4-(N-propanoylanilino)piperidine-4-carboxylate
23
SevofluraneapprovedPhase 4, Phase 1, Phase 238128523-86-65206
Synonyms:
1,1,1,3,3,3-Hexafluoro-2-(fluoromethoxy)propane
28523-86-6
AC-15484
AC1L1JU0
BRN 2041023
Bax 3084
C009250
C07520
C4H3F7O
CHEBI:9130
CHEMBL1200694
CID5206
D00547
DB01236
F0691
Fluoromethyl 1,1,1,3,3,3-Hexafluoroisopropyl Ether
Fluoromethyl 2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
I14-13357
LS-67851
MR6S4
 
MR_6S4
MolPort-001-775-746
NCGC00167421-01
PC4681
Sevofluran
Sevoflurane
Sevoflurane (JAN/USAN/INN)
Sevoflurane [USAN:INN:BAN:JAN]
Sevoflurano
Sevoflurano [INN-Spanish]
Sevofluranum
Sevofluranum [INN-Latin]
Sevofrane
Sevorane
Sojourn
UNII-38LVP0K73A
Ultane
Ultane (TN)
ZINC01530810
fluoromethyl hexafluoroisopropyl ether
fluoromethyl-2,2,2-trifluoro-1-(trifluoromethyl)ethyl ether
sevoflurane
24
DoxazosinapprovedPhase 45474191-85-83157
Synonyms:
1-(4-Amino-6,7-Dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-chinazolinyl)-4-(2,3-dihydro-1,4-benzodioxixin-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(1,4-benzodioxan-2-ylcarbonyl)piperazin
1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-[4-(1,4-benzodioxan-2-yl)carpiperazin-1-yl)]-6,7-dimethoxyquinazoline mesylate
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-bis(methyloxy)quinazolin-4-amine
2-[4-(2,3-dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine
2-{4-[(2,3-dihydro-1,4-benzodioxin-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine
74191-85-8
77883-43-3 (mesylate)
AC-11062
AC1L1FAT
AC1Q470P
AC1Q4EXN
AKOS001681453
BPBio1_000963
BRD-A13188892-066-03-3
BSPBio_000875
C06970
C23H25N5O5
CHEBI:4708
CHEMBL707
CID3157
CPD000097306
Cardura
Cardura XL
Cardura XL (TN)
Cardura-1
Cardura-2
Cardura-4
ChemDiv2_005017
D07874
D9815_SIGMA
DB00590
 
Doxazosin
Doxazosin (INN)
Doxazosin Mesylate
Doxazosin [INN:BAN]
Doxazosin mesilate
Doxazosin mesylate
Doxazosina
Doxazosina [Spanish]
Doxazosine
Doxazosine [French]
Doxazosinum
Doxazosinum [Latin]
HMS1383E01
HMS2090C20
I06-1346
IDI1_003732
L000738
LS-110228
Lopac0_000474
MolPort-001-684-491
NCGC00018158-06
NCGC00089775-02
Normothen
Oprea1_259518
Prestwick0_000858
Prestwick1_000858
Prestwick2_000858
Prestwick3_000858
SAM002589981
SPBio_002796
UK 33274
UK-33274
UNII-NW1291F1W8
[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(2,3-dihydro-1,4-benzodioxin-3-yl)methanone
doxazosin
25
Darbepoetin alfaapproved, investigationalPhase 4, Phase 315611096-26-7
Synonyms:
Aranesp
 
Epoetin
Erythropoietin precursor
26
Valsartanapproved, investigationalPhase 4, Phase 2260137862-53-460846
Synonyms:
(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
(S)-N-Valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(S)-N-valeryl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]-methyl}-valine
(s)-2-(n-((2'-(1h-tetrazol-5-yl)biphenyl-4-yl)methyl)pentanamido)-3-methylbutanoic acid
137862-53-4
AC-4543
AC1L1U1M
AC1Q5QIK
Ambap137862-53-4
Aventis brand of valsartan
BIDD:GT0345
BRD-K45158365-001-02-3
BSPBio_003501
Bio-0796
C081489
C24H29N5O3
CEPA brand of valsartan
CGP 48933
CGP-48933
CHEBI:9927
CHEMBL1069
CID60846
CPD000466318
D00400
DB00177
Diovan
Diovan (TN)
Diovan, Valsartan
Esteve brand of valsartan
HMS1922L21
HMS2051L12
HMS2093K22
HSDB 7519
KBio2_002287
KBio2_004855
KBio2_007423
KBio3_003006
KBioGR_001078
KBioSS_002289
Kalpress
 
L-Valine, N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]- (9CI)
LS-161334
Lacer brand of valsartan
MLS000759423
MLS001424088
Miten
MolPort-002-507-854
MolPort-003-666-608
N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine
N-(P-(O-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-(p-(o-1H-Tetrazol-5-ylphenyl)benzyl)-N-valeryl-L-valine
N-Pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl}-L-valine
N-pentanoyl-N-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-L-valine
N-valeryl-N-((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)valine
Nisis
Nisis||
Novartis brand of valsartan
Provas
S1894_Selleck
SAM001246581
SMR000466318
SPBio_001260
SPECTRUM1505209
Sanol brand of valsartan
Schwarz brand of valsartan
Spectrum2_001120
Spectrum3_001831
Spectrum4_000749
Spectrum5_001582
Spectrum_001796
TL8000869
Tareg
UNII-80M03YXJ7I
Vals
Valsarran
Valsartan
Valsartan (JAN/USAN/INN)
Valsartan [USAN:INN]
valsartan
walsartan
|Tareg
27
Ranolazineapproved, investigationalPhase 4, Phase 3, Phase 274142387-99-356959
Synonyms:
( -)-Ranolazine
(-)-Ranolazine
142387-99-3
95635-55-5
AC-1673
AC1L1M17
AC1Q5LYD
BRD-A97674275-001-01-9
BSPBio_002276
CHEMBL1404
CID56959
CVT-303
D05700
DB00243
HMS1922F16
HMS2090L09
HMS2093D21
I01-2008
I06-0160
KEG-1295
LS-187267
Latixa
Lopac0_001062
 
MLS002154149
MolPort-003-666-653
N-(2,6-dimethylphenyl)-2-[4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl]acetamide
NCGC00015897-05
NCGC00095177-01
NCGC00095177-02
NCGC00095177-03
RAN D
RANOLAZINE
RS-43285
RS-43285-003
Ran4
Ranexa
Ranexa (TN)
Ranexa, Ranolazine
Ranolazine (USAN/INN)
Ranolazine 2HCl
Ranolazine Dihydrochloride
Ranolazine dihydrochloride
S1799_Selleck
SMR000857382
SPECTRUM1505366
UNII-A6IEZ5M406
ranolazine
28
Epoetin alfaapprovedPhase 4, Phase 2612113427-24-0
Synonyms:
Epogen
 
Erythropoietin precursor
Procrit
29
Metoprololapproved, investigationalPhase 4, Phase 2, Phase 318637350-58-64171
Synonyms:
(+/-)-Metoprolol
(RS)-Metoprolol
1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)propan-2-ol
1-(Isopropylamino)-3-(p-(2-methoxyethyl)phenoxy)-2-propanol
1-(isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]propan-2-ol
1-[(1-methylethyl)amino]-3-({4-[2-(methyloxy)ethyl]phenyl}oxy)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
1-[4-(2-methoxyethyl)phenoxy]-3-propan-2-ylamino-propan-2-ol
3-[4-(2-methoxyethyl)phenoxy]-1-(propan-2-ylamino)propan-2-ol
37350-58-6
51384-51-1
54163-88-1
AB00053499
AC-19022
AC1L1HKM
AstraZeneca Brand of Metaoprolol Tartrate
AstraZeneca Brand of Seloken
BRD-A03623303-045-02-0
Beatrolol
Beloc
Beloc Duriles
Beloc-Duriles
BelocDuriles
Betaloc
Betaloc Astra
Betaloc-Astra
BetalocAstra
Betalok
C07202
CCRIS 4198
CGP 2175
CGP-2175
CGP2175
CHEBI:6904
CHEMBL13
CID4171
D008790
D02358
DB00264
Dl-Metoprolol
Dutoprol
EINECS 253-483-7
EINECS 257-166-4
H 93 26
H 93-26
H 9326
HMS2090B15
 
HSDB 6531
I01-7125
I06-0125
Jsp006606
L000669
LOPRESSIDONE
LS-122450
Leiras Brand of Metoprolol Succinate or Metoprolol Tartrate
Lopresor
Lopresoretic
Lopressor
Lopressor HCT
Meijoprolol
Metohexal
Metoprolol
Metoprolol (USAN/INN)
Metoprolol Succinate
Metoprolol Succinate extended-release
Metoprolol Tartrate
Metoprolol [USAN:INN:BAN]
Metoprolol succinate
Metoprolol tartrate
Metoprololum
Metoprololum [INN-Latin]
Metroprolol
MolPort-005-938-039
NCGC00021148-02
NCGC00021148-03
NCGC00021148-04
Novartis Brand of Metprolol Tartrate
Preblok
Prelis
Presolol
Selo-Zok
Seloken
Seloken AstraZeneca Brand
Selopral
Seroken
Spesicor
Spesikor
TOPROL-XL
Tartrate, Metoprolol
Toprol
Toprol XL
Toprol-XL
UNII-GEB06NHM23
dl-Metoprolol
metoprolol
30
Benazeprilapproved, investigationalPhase 44586541-75-55362124
Synonyms:
2-[(3S)-3-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-2-oxo-4,5-dihydro-3H-1-benzazepin-1-yl]acetic acid
86541-75-5
AC1NSFPL
BIDD:GT0800
BRD-K49807096-003-02-3
BSPBio_003487
Benazepril
Benazepril (INN)
Benazepril HCl
Benazepril Hydrochloride
Benazepril Sandoz
Benazepril Sandoz (TN)
Benazepril [INN:BAN]
Benazeprilum
Benazeprilum [Latin]
Briem
C06843
CGS-14824-A
CHEBI:3011
CHEMBL838
CID5362124
Cibacen
Cibacene
D07499
DB00542
 
Forteekor [veterinary]
Forteekor [veterinary] (TN)
KBio2_002457
KBio2_005025
KBio2_007593
KBio3_002707
KBioGR_000812
KBioSS_002464
LS-27973
Lotensin
NCGC00165740-01
NCGC00165740-02
SPBio_000343
STK627447
Spectrum2_000482
Spectrum3_001674
Spectrum4_000286
Spectrum5_001546
Spectrum_001922
UNII-UDM7Q7QWP8
[(3S)-3-({(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}amino)-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
[(3S)-3-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepin-1-yl]acetic acid
benazapril
benazepril
benzazepril
31
Carvedilolapproved, investigationalPhase 414972956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
32
EnalaprilapprovedPhase 4, Phase 310475847-73-35362032, 40466924
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(S)-1-(N-(1-(Ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline
(S)-1-{(S)-2-[1-((S)-ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester
75847-73-3
AC1NTUS5
Analapril
BIDD:GT0751
BPBio1_000340
BSPBio_000308
BSPBio_003035
Bonuten
C06977
CAS-76095-16-4
CHEBI:116847
CHEBI:4784
CHEMBL578
CID5388962
D07892
DivK1c_000408
Enalapril
Enalapril (INN)
Enalapril (TN)
Enalapril Bp
Enalapril Maleate
Enalapril Richet
Enalaprila
Enalaprila [INN-Spanish]
Enalaprilat
Enalaprilum
 
Enalaprilum [INN-Latin]
Gadopril
HMS2090E08
IDI1_000408
KBio1_000408
KBio2_001787
KBio2_004355
KBio2_006923
KBio3_002535
KBioGR_000355
KBioSS_001787
Kinfil
LS-190651
MolPort-002-885-877
N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline
N-{(1S)-1-[(ethyloxy)carbonyl]-3-phenylpropyl}-L-alanyl-L-proline
NCGC00016932-01
NCGC00021569-04
NCGC00021569-05
NCGC00021569-06
NINDS_000408
Prestwick3_000314
SPBio_001349
Spectrum2_001455
Spectrum3_001478
Spectrum4_000008
Spectrum5_001107
Spectrum_001307
Vaseretic
Vasotec
Vasotec IV
enalapril
33
Acetylcarnitineapproved, investigationalPhase 4383040-38-81
Synonyms:
(+-)-Acetylcarnitine
(-)-Acetylcarnitine
(R)-Acetylcarnitine
ALCAR
Acetyl-L-(-)-carnitine
Acetyl-L-carnitine
Acetyl-carnitine
Acetylcarnitine
 
L-Acetylcarnitine
L-Carnitine acetyl ester
L-O-Acetylcarnitine
Levocarnitine acetyl
Nicetile
O-Acetyl-L-carnitine
O-Acetylcarnitine
O-acetyl-L-carnitine
acetyl-L-carnitine
34
AtorvastatinapprovedPhase 4, Phase 3690134523-00-560823
Synonyms:
(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(3R,5R)-7-[3-(anilinocarbonyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid
(R-(R*,R*))-2-(4-Fluorophenyl)-beta,delta-dihydroxy-5-(1-methylethyl)-3-phenyl-4-((phenylamino)carbonyl)-1H-pyrrole-1-heptanoic acid
(betaR,deltaR)-2-(p-Fluorophenyl)-beta,delta-dihydroxy-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrole-1-heptanoic acid
134523-00-5
134523-03-8
7-[2-(4-FLUORO-PHENYL)-5-ISOPROPYL-3-PHENYL-4-PHENYLCARBAMOYL-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID
AC-15611
AC1L1TZT
AC1Q1OZQ
AKOS000281127
Atogal
Atorlip
Atorpic
Atorvastatin
Atorvastatin (INN)
Atorvastatin Calcium
Atorvastatin [INN:BAN]
Atorvastatin acid
Atorvastatin calcium
BIDD:GT0336
C06834
C33H35FN2O5
CCRIS 7159
CHEBI:39548
CHEMBL1487
CI 981
CID60823
Cardyl
D07474
DB01076
Faboxim
 
HSDB 7039
Hipolixan
LS-136975
Lipitor
Lipitor (TN)
Lipitor(TM)
Lipotropic
Lipovastatinklonal
Liprimar
Lowden
MolPort-000-883-773
NCGC00159458-02
Normalip
Sincol
Sortis
Sortis (TN)
Sotis
Torvacard
Torvast
Totalip
Tozalip
Tulip
UNII-A0JWA85V8F
Vastina
Xanator
Xarator
Xavator
Zurinel
atorvastatin
atorvastatina
atorvastatine
atorvastatinium
atrovastin
nchembio.301-comp8
35
AspirinapprovedPhase 4, Phase 397150-78-22244
Synonyms:
11126-35-5
11126-37-7
1oxr
2-(ACETYLOXY)benzoic acid
2-(Acetyloxy)benzoate
2-(Acetyloxy)benzoic acid
2-Acetoxybenzenecarboxylic acid
2-Acetoxybenzoate
2-Acetoxybenzoic acid
2-Carboxyphenyl acetate
2349-94-2
26914-13-6
50-78-2
7 Select Adult Chewable Aspirin
7 Select Aspirin
8-hour Bayer
98201-60-6
A 5376
A.S.A
A.S.A.
A.S.A. Empirin
A.S.A. empirin
A2093_SIGMA
A3160_SIGMA
A5376_SIGMA
A6810_SIGMA
AB1003266
AC 5230
AC1L1D8U
AC1Q1LA0
ACETYLSALICYLIC ACID
AI3-02956
AIN
AKOS000118884
ASA
Acenterine
Acesal
Acetal
Acetard
Aceticyl
Acetilsalicilico
Acetilum acidulatum
Acetisal
Acetol
Acetonyl
Acetophen
Acetosal
Acetosalic acid
Acetosalin
Acetoxybenzoic acid
Acetylin
Acetylsal
Acetylsalicylate
Acetylsalicylic acid
Acetylsalicylsaeure
Acetylsalicylsaure
Acetylsalycilic acid
Acetyonyl
Acetysal
Acetysalicylic acid
Acide 2-(acetyloxy)benzoique
Acide acetylsalicylique
Acide acétylsalicylique
Acido O-acetil-benzoico
Acido acetilsalicilico
Acidum acetylsalicylicum
Acimetten
Acisal
Acylpyrin
Adiro
Adult Chewable Low Dose Aspirin
Adult Low Dose Aspirin
Adult Low Dose Aspirin Enteric Safety Coated
Adult Low Dose Enteric Coated Aspirin
Adult Low Strength Aspirin
Aloxiprimum
Asacard
Asagran
Asaphen
Asatard
Ascoden-30
Ascriptin Maximum Strength Buffered Aspirin
Ascriptin Regular Strength Buffered Aspirin
Aspalon
Aspec
Aspergum
Aspi-cor
Aspir Low
Aspir-Mox
Aspirdrops
Aspirin
Aspirin (JP15/USP)
Aspirin 81 Mg
Aspirin 81 Mg Low Dose
Aspirin Adult Low Dose
Aspirin Adult Low Strength
Aspirin Adult Low Strength Aspirin
Aspirin Adult low strength
Aspirin Chewable Low Dose
Aspirin Delayed Release
Aspirin EC
Aspirin EXTRA STRENGTH
Aspirin Ec
Aspirin Enteric
Aspirin Enteric Coated
Aspirin Enteric Coated Low Dose
Aspirin Enteric Safety Coated
Aspirin Enteric Safety-Coated
Aspirin Low Dose
Aspirin Low Dose Chewable
Aspirin Low Dose Enteric Coated
Aspirin Low Dose Safety Coated
Aspirin Low Strength
Aspirin Nsaid
Aspirin Regular Strength
Aspirin Regular Strength regular strength
Aspirin Regular strength
Aspirin Safety Coated
Aspirin Safety Coated Adult Low Dose
Aspirin Safety coated
Aspirin Thin coated
Aspirin [BAN:JAN]
Aspirin adult low dose
Aspirin adult low strength
Aspirin enteric safety coated
Aspirin low dose
Aspirin low dose chewable
Aspirin low dose enteric coated
Aspirin regular strength
Aspirina 03
Aspirine
Aspiring
Asprin
Aspro
Aspro Clear
Asteric
Azetylsalizylsaeure
Azetylsalizylsäure
BIDD:GT0118
BRN 0779271
Bay-e-4465
Bayer
Bayer Advanced Aspirin Extra Strength
Bayer Advanced Aspirin Regular Strength
Bayer Aspirin 8 Hour
Bayer Aspirin Regimen Chewable Low Dose Aspirin Orange
Bayer Aspirin Regimen Regular Strength
Bayer Buffered
Bayer Chewable - Aspirin Regimen Low Dose Aspirin Cherry Flavored
Bayer Extra Strength Aspirin For Migraine Pain
Bayer Fast Release
Bayer Genuine Aspirin
Bayer Low Dose
Bayer Plus
Bayer Plus Extra Strength
Bayer Womens
Benaspir
Bi-prin
Bialpirina
Bialpirinia
Buffered Aspirin
Bufferin
Bufferin LOW DOSE BUFFERED ASPIRIN
C01405
CCRIS 3243
CHEBI:15365
CHEMBL25
CID2244
Caprin
Cardioaspirin
Cardioaspirina
Care One Aspirin
Cemirit
Chewable Adult Low Dose Aspirin
Chewable Aspirin
Chewable Low Dose Aspirin
Claradin
Clariprin
Colfarit
Contrheuma retard
Coricidin
Critical Care Aspirin To Go
Crystar
D00109
D001241
DB00945
Decaten
Delgesic
Dg Health Aspirin
Direct Safety Aspirin
Dispril
DivK1c_000555
Dolean pH 8
Duramax
ECM
EINECS 200-064-1
EU-0100038
Easprin
Easprin (TN)
Ec-81aspirin Enteric Coated
Ecolen
Ecotrin
Ecotrin Regular Strength
Empirin
Empirin with Codeine
Endosprin
Endydol
Enteric Aspirin
Enteric Coated Aspirin
Enteric Coated Aspirin Regular Strength
Enteric Coated Aspirin Regular strength
Enteric Coated Aspirin regular strength
Enteric Coated Asprin 81 Mg
Enteric Coated Low Dose Aspirin
 
Enteric Safety Coated Aspirin
Entericin
Enterophen
Enterosarein
Enterosarine
Entrophen
Equaline Aspirin
Equaline Aspirin adult low dose
Equate Aspirin
Equate Aspirin chewable
Extren
Fasprin
Flanax Aspirin Pain Reliever
Formucare Aspirin
Genuine Aspirin
Globentyl
Globoid
Good Neighbor Pharmacy Aspirin
Good Neighbor Pharmacy Aspirin Enteric Safety Coated
Good Neighbor Pharmacy Aspirin orange flavor chewable
Good Sense Aspirin
Good Sense Aspirin Enteric Safety Coated
HMS1920E13
HMS2090G03
HMS2091K13
HMS501L17
HSDB 652
Handy Solutions Genuine Aspirin Bayer
Health Mart Aspirin
Health Mart Regular Strength Enteric Coated Aspirin
Health Sense Adult Chewable Low Strength Aspirin
Health Sense Aspirin 81
Health Sense Ecpirin
Healthy Accents Aspirin
Helicon
Henry Schein Aspirin
I14-7505
IDI1_000555
Idragin
Istopirin
KBio1_000555
KBio2_001725
KBio2_002271
KBio2_004293
KBio2_004839
KBio2_006861
KBio2_007407
KBio3_002149
KBio3_002751
KBioGR_000398
KBioGR_002271
KBioSS_001725
KBioSS_002272
Kapsazal
Kroger Value Aspirin
Kyselina 2-acetoxybenzoova
Kyselina acetylsalicylova
LS-143
Leader Aspirin
Leader Cardinal Health Aspirin
Leader Low Dose Aspirin
Levius
Lopac-A-5376
Lopac0_000038
Low Dose Adult Aspirin
Low Dose Aspirin
Low Dose Aspirin 81 Mg Safety Coated
Low Dose Aspirin Enteric Safety Coated
Low Dose Asprin
Low Dose Chewable Aspirin
Low Dose Miniprin Enteric Safety Coated
Low Dose Pain Relief Aspirin
Low Strength Chewable Aspirin
Low-dose Aspirin
MLS001055329
MLS001066332
MLS001336045
MLS001336046
Magnecyl
Measurin
Medi First Plus Aspirin
Medi-first Aspirin
Medique Aspirin
Medisyl
Micristin
Micro-coated Aspirin
Miniprin
MolPort-000-871-622
NCGC00015067-01
NCGC00015067-04
NCGC00015067-09
NCGC00090977-01
NCGC00090977-02
NCGC00090977-03
NCGC00090977-04
NCGC00090977-05
NCGC00090977-06
NCGC00090977-07
NCI60_002222
NINDS_000555
NSC 27223
NSC27223
NSC406186
Neuronika
North Aspirin
Novasen
Novid
Nu-seals
Nu-seals aspirin
O-(Acetyloxy)benzoate
O-(Acetyloxy)benzoic acid
O-Acetoxybenzoate
O-Acetoxybenzoic acid
O-Acetylsalicylic acid
O-Carboxyphenyl acetate
O-accetylsalicylic acid
O-acetylsalicylic acid
PL-2200
Pain Relief Aspirin
Pain Relief Aspirin Low Dose
Persistin
Pharbest Aspirin 325mg
Pharbest Regular Strength Aspirin
Pharmacin
Pirseal
Plus Pharma NSAID 325 mg
Plus Pharma Nsaid Aspirin
Polopirin
Polopiryna
Premaspin
R16CO5Y76E [UNII]
Rapid Comfort Aspirin
Regular Strength Aspirin
Regular Strength Aspirin Ec
Regular Strength Buffered Aspirin
Regular Strength Enteric Aspirin
Regular Strength Enteric Coated Aspirin
Regular Strength Pain Relief
Regular Strength Tri-buffered Aspirin
Rexall Aspirin
Rheumin tabletten
Rheumintabletten
Rhodine
Rhonal
Ronal
Rugby Aspirin
Rx Act Aspirin
S-211
SMR000059138
SP 189
SPBio_001838
SPECTRUM1500130
ST075414
Safety Coated Aspirin
Safety Coated Enteric Aspirin
Salacetin
Salcetogen
Saletin
Salicylic acid acetate
Salicylic acid, acetate
Salospir
Smart Health Aspirin regular strength
Smart Sense Aspirin
Solfrin
Solprin
Solprin acid
Solpyron
Solupsan
Solves - Aspirin Cherry
Spectrum2_001899
Spectrum3_001295
Spectrum4_000099
Spectrum5_000740
Spectrum_001245
Spira-Dine
St. Joseph
St. Joseph Aspirin for Adults
St. Joseph Chewable Aspirin
St. Joseph Safety Coated Aspirin
Sunmark Aspirin
Sunmark Aspirin Regular Strength
Sunmark Aspirin adult low strength
Sunmark Aspirin low dose
Supac
Tasprin
Temperal
Toldex
Topcare Aspirin
Tri-buffered Aspirin
Triaminicin
Triple-sal
UNII R16CO5Y76E
UNII-R16CO5Y76E
UNII=R16CO5Y76E
UNM-0000306102
Uncoated Aspirin
Value Pharma Aspirin Pain Reliever
Value Pharmapain Reliever Extra Strength
Vanquish
WLN: QVR BOV1
XAXA
Xaxa
Yasta
ZORprin
Zee Aspirin
aspirin
cMAP_000006
component of Midol
component of Synirin
nchem.859-comp6
o-Acetoxybenzoic acid
o-Carboxyphenyl acetate
o-acetoxybenzoic acid
o-carboxyphenyl acetate
ácido acetilsalicílico
36
HydrochlorothiazideapprovedPhase 437558-93-53639
Synonyms:
125727-50-6
3,4-Dihydro-6-chloro-7-sulfamyl-1,2, 4-benzothi
3,4-Dihydrochlorothiazide
58-93-5
6-Chloro-7-sulfamoyl-3, 4-dihy
8049-49-8
AB00052012
AC-11072
AC1L1GDT
AC1Q55FM
AF-614/30832002
AKOS000121373
ARONIS24316
Acesistem
Acuilix
Acuretic
Aldactazide
Aldactazide 25/25
Aldazida
Aldectazide 50/50
Aldoril
Ambap58-93-5
Apo-Hydro
Apresazide
Aquarills
Aquarius
Aquazide H
Aquazide-H
BAS 00371709
BIDD:GT0153
BPBio1_000019
BRD-K13078532-001-05-2
BRN 0625101
BSPBio_000017
BSPBio_002132
Bio-0714
Bremil
Briazide
C7H8ClN3O4S2
CAS-58-93-5
CCRIS 2082
CHEMBL435
CID3639
CPD000035778
Caplaril
Capozide
Carozide
Catiazida
Chlorizide
Chlorosulthiadil
Chlorothiazide
Chlorsulfonamidodihydrobenzothiadiazine dioxide
Chlorzide
Chlothia
Cidrex
Clorana
Component of Butizide Prestabs
Concor Plus
Condiuren
D00340
D006852
DB00999
Diaqua
Dichlorosal
Dichlorotride
Dichlothiazide
Dichlotiazid
Dichlotride
Diclotride
Dicyclotride
Didral
Dihydran
Dihydrochlorothiazid
Dihydrochlorothiazide
Dihydrochlorothiazidum
Dihydrochlorurit
Dihydrochlorurite
Dihydroxychlorothiazidum
Direma
Disalunil
Disothiazid
Diu 25 Vigt
Diu-Melusin
Diu-melusin
Diuril
Diurogen
DivK1c_000289
Dixidrasi
Drenol
Dyazide
EINECS 200-403-3
EU-0100614
Esidrex
Esidrix
Esidrix (TN)
Esimil
Esoidrina
FT-0082750
Fluvin
H 4759
H1274
H2910_SIAL
H4759_SIAL
HCT
HCT-Isis
HCTZ
HCZ
HMS1568A19
HMS1920D19
HMS2091L05
HMS500O11
HMS553N04
HSDB 3096
Hidril
Hidro-Niagrin
Hidrochlortiazid
Hidroclorotiazida
Hidroclorotiazida [INN-Spanish]
Hidroronol
Hidrosaluretil
Hidrotiazida
Hyclosid
Hydrex-semi
Hydril
Hydro Par
Hydro-Aquil
Hydro-D
Hydro-Diuril
Hydro-Saluric
Hydro-T
Hydro-chlor
HydroDIURIL
Hydrochlorat
Hydrochloro Thiazide
Hydrochlorot
Hydrochlorothiazid
Hydrochlorothiazide
Hydrochlorothiazide (JP15/USP/INN)
Hydrochlorothiazide Intensol
Hydrochlorothiazide [INN:BAN:JAN]
 
Hydrochlorothiazidum
Hydrochlorothiazidum [INN-Latin]
Hydrochlorthiazide
Hydrochlorthiazidum
Hydrocot
Hydrodiuretic
Hydrodiuril
Hydropres
Hydrosaluric
Hydrothide
Hydrozide
Hydrozide Injection, Veterinary
Hypothiazid
Hypothiazide
Hytrid
Hyzaar
I09-0531
IDI1_000289
Idroclorotiazide
Idroclorotiazide [DCIT]
Idrotiazide
Inderide
Inderide 80/25
Indroclor
Ivaugan
Jen-Diril
KBio1_000289
KBio2_001357
KBio2_003925
KBio2_006493
KBio3_001352
KBioGR_000351
KBioSS_001357
LS-243
Lopac-H-4759
Lopac0_000614
Lopressor HCT
Lotensin HCT
Lotensin Hct
MLS000069619
Manuril
Maschitt
Maxzide
Maybridge Compound 10
Maybridge1_004336
Mazide 25 mg
Medozide
Megadiuril
Microzide
Microzide (TN)
Mictrin
Mikorten
Modurcen
Moduretic
MolPort-000-144-465
NCGC00015508-01
NCGC00015508-02
NCGC00015508-03
NCGC00015508-07
NCGC00015508-12
NCGC00021906-03
NCGC00021906-04
NCGC00021906-05
NCGC00021906-06
NCGC00021906-07
NCGC00021906-08
NCI-C55925
NCI60_004317
NINDS_000289
NSC 53477
NSC53477
Natrinax
Nefrix
Nefrol
Neo-Codema
Neo-Flumen
Neo-Minzil
Neo-codema
Neoflumen
Newtolide
Novodiurex
Oprea1_357174
Oretic
Pantemon
Panurin
Prestwick0_000009
Prestwick1_000009
Prestwick2_000009
Prestwick3_000009
Prestwick_263
Prinzide
Raunova Plus
Ro-Hydrazide
Ro-hydrazide
Roxane
S1708_Selleck
SAM002554901
SMR000035778
SPBio_001259
SPBio_001938
SPECTRUM1500335
STK315354
Saldiuril
Sectrazide
Selozide
Ser-Ap-Es
Servithiazid
Spectrum2_001040
Spectrum3_000456
Spectrum4_000006
Spectrum5_000824
Spectrum_000877
Spironazide
Su 5879
Tandiur
Thiaretic
Thiuretic
Thlaretic
Timolide
UNII-0J48LPH2TH
Unazid
Unipres
Urodiazin
Urozide
Vaseretic
Vetidrex
WLN: T66 BSWM EM DHJ HG ISZW
ZINC00896569
Ziac
Zide
adiazine-1,1-dioxide
component of Aldactazide
component of Aldoril
component of Caplaril
component of Cyclex
component of Dyazide
component of Esimil
diclot ride
dro-2H-1,2,4-benzothiadiazine 1,1-dioxide
hydrochlorothiazide
panurin dichloride
37
ChlorthalidoneapprovedPhase 45377-36-12732
Synonyms:
(+-)-Chlorthalidone
(+-)-Hygroton
1-Keto-3-(3'-sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline
1-Oxo-3-(3-sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline
1-keto-3-(3'-Sulfamyl-4'-chlorophenyl)-3-hydroxyisoindoline
1-oxo-3-(3-Sulfamyl-4-chlorophenyl)-3-hydroxyisoindoline
2-Chloro-5-(1-hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide
2-Chloro-5-(1-hydroxy-3-oxo-2,3-dihydro-1H-isoindol-1-yl)benzenesulfonamide
2-chloro-5-(1-Hydroxy-3-oxo-1-isoindolinyl)benzenesulfonamide
2-chloro-5-(1-hydroxy-3-oxo-2H-isoindol-1-yl)benzenesulfonamide
2-chloro-5-(2,3-dihydro-1-Hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide
2-chloro-5-(2,3-dihydro-1-hydroxy-3-oxo-1H-isoindol-1-yl)benzenesulfonamide
3-(4'-Chloro-3'-sulfamoylphenyl)-3-hydroxyphthalimidine
3-(4'-chloro-3'-Sulfamoylphenyl)-3-hydroxyphthalimidine
3-Hydroxy-3-(4-chloro-3-sulfamylphenyl)phthalimidine
5-22-07-00602 (Beilstein Handbook Reference)
77-36-1
A3836/0162845
AB00051946
AC-11367
AC1L1ECB
AC1Q558X
BPBio1_000487
BRD-A26384407-001-05-3
BRN 0312295
BSPBio_000441
BSPBio_002017
C14H11ClN2O4S
C2775_FLUKA
C2775_SIGMA
CHEBI:3654
CHEMBL1055
CID2732
CPD000058635
Chlorothalidone
Chlorphthalidolone
Chlorphthalidone
Chlortalidone
Chlortalidone (JAN/INN)
Chlortalidonum
Chlortalidonum [INN-Latin]
Chlorthalidon
Chlorthalidone
Chlorthalidone (USP)
Chlorthalidone [USAN:INN:BAN]
Clodronic Acid
Clortalidona
Clortalidona [INN-Spanish]
Clortalidone
Clortalidone [DCIT]
D00272
D002752
DB00310
DivK1c_000731
EINECS 201-022-5
Famolin
G 33182
G-33182
HMS1569G03
HMS1920M09
 
HMS2091E12
HMS502E13
HSDB 3035
Higroton
Hydro-Long
Hygroton
Hygroton (TN)
I06-0208
IDI1_000731
Igroton
Isoren
KBio1_000731
KBio2_000626
KBio2_003194
KBio2_005762
KBio3_001237
KBioGR_001574
KBioSS_000626
LS-31408
MLS000069531
MolPort-002-736-049
NCGC00094616-01
NCGC00094616-02
NCGC00094616-03
NCGC00094616-04
NINDS_000731
NSC 69200
NSC69200
Natriuran
Oksodolin (oxodolin)
Oradil
Oxodolin
Oxodoline
Phthalamodine
Phthalamudine
Prestwick0_000351
Prestwick1_000351
Prestwick2_000351
Prestwick3_000351
Prestwick_759
Racemic chlorthalidone
Renon
SAM002589983
SMR000058635
SPBio_000058
SPBio_002362
SPECTRUM1500187
ST088141
STK686335
Saluretin
Spectrum2_000099
Spectrum3_000349
Spectrum4_000957
Spectrum5_000743
Spectrum_000146
Tenoretic
Thalitone
Thalitone (TN)
UNII-Q0MQD1073Q
Urolin
Zambesil
chlorthalidone
38
DopamineapprovedPhase 4, Phase 3, Phase 2281462-31-7, 51-61-6681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine Hcl
Dopamine Hydrochloride
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
 
KBio1_000780
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
39
Tadalafilapproved, investigationalPhase 4, Phase 1, Phase 2137171596-29-5110635
Synonyms:
(6R,12AR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
171596-29-5
1xoz
6-BENZO[1,3]dioxol-5-yl-2-methyl-2,3,6,7,12,12a-hexahydro-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
AC1L380B
ADCIRCA
Acdirca
Adcirca
C429886
CHEBI:41488
CHEMBL779
CID110635
CPD000466321
Cialis
Cialis (TN)
Cialis, GF 196960, IC 351, ICOS 351, Tadalafil
D02008
DB00820
FT-0080116
GF 196960
GF-196960
 
HMS2051N17
HSDB 7303
IC 351
IC-351
ICOS 351
Ic351
KS-1117
LS-186558
LS-187015
LS-187770
Lilly brand of tadalafil
MLS000759426
MLS001165782
MLS001195644
MLS001424132
MolPort-002-885-864
S1512_Selleck
SAM001246586
SMR000466321
Tadalafil
Tadalafil (JAN/USAN/INN)
Tadalafil [USAN]
Tadanafil
UNII-742SXX0ICT
ZINC03993855
40
VerapamilapprovedPhase 411252-53-92520
Synonyms:
(+-)-Verapamil
(+/-)-VERAPAMIL
(1)-3-(3,4-Dimethoxyphenyl)-6-((5,6-dimethoxyphenethyl)methylamino)hexane-3-carbonitrile
2-(3,4-Dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methyl-amino]-2-(1-methylethyl) pentanenitrile
2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile
2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile
5-((3,4-Dimethoxyphenethyl)methylamino)-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
5-[(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile
52-53-9
56949-77-0
AB00053495
AC-16016
AC1L1DV5
Akilen
Anpec
Apo-Verap
Arpamyl
Arpamyl LP
BPBio1_000268
BRD-A09533288-001-02-7
BRD-A09533288-003-05-6
BSPBio_000242
BSPBio_001513
BSPBio_002358
Berkatens
Bio-0754
Bio1_000425
Bio1_000914
Bio1_001403
Bio2_000233
Bio2_000713
C07188
C27H38N2O4
CCRIS 6749
CHEBI:9948
CHEMBL6966
CID2520
CP-16533-1
CP-165331
Calan
Calan SR
Calan Sr
Calan sr
Calaptin
Calaptin 240 SR
Calcan
Cardiabeltin
Cardiagutt
Cardibeltin
Cardioprotect
Caveril
Civicor
Civicor Retard
Coraver
Cordilox
Cordilox SR
Corpamil
Covera-HS
Covera-Hs
Covera-hs
D-365
D02356
DB00661
Dexverapamil
Dignover
Dilacoran
Dilacoran HTA
DivK1c_000399
Drosteakard
Durasoptin
EINECS 200-145-1
EINECS 260-462-6
Elthon
FT-0080127
Falicard
Finoptin
Flamon
Geangin
HMS1791L15
HMS1989L15
HMS2089H17
Harteze
Hexasoptin
Hexasoptin Retard
Hormitol
I06-0063
IDI1_000399
IDI1_033983
Ikacor
Ikapress
Inselon
Iproveratril
Isoptimo
Isoptin
Isoptin Retard
Isoptin SR
Isoptin sr
Isoptine
Isoptino
Isotopin
Izoptin
Jenapamil
KBio1_000399
KBio2_000233
KBio2_002343
KBio2_002801
KBio2_004911
KBio2_005369
KBio2_007479
KBio3_000465
KBio3_000466
KBio3_002823
KBioGR_000233
 
KBioGR_001372
KBioGR_002343
KBioSS_000233
KBioSS_002346
L001330
LS-174
Lekoptin
Lodixal
Lopac0_001237
Magotiron
Manidon
Manidon Retard
MolPort-000-721-258
NCGC00016083-14
NCGC00024710-04
NCGC00024710-05
NCGC00024710-06
NCGC00024710-07
NCGC00024710-08
NCGC00024710-09
NCI60_020143
NINDS_000399
NSC272366
NU-Verap
Novapamyl LP
Novo-Veramil
Nu-Verap
Ormil
Praecicor
Prestwick0_000141
Prestwick1_000141
Prestwick2_000141
Prestwick3_000141
Quasar
Rapam
Robatelan
SID104171262
SID124881789
SID124881790
SPBio_001820
SPBio_002181
STK538085
Securon
Spectrum2_001740
Spectrum4_000906
Spectrum5_001786
Tarka
UNII-CJ0O37KU29
Univer
Univex
VERAPAMIL
Vasolan
Vasomil
Vasopten
Vera-Sanorania
Verabeta
Veracaps SR
Veracim
Veracor
Verahexal
Veraloc
Veramex
Veramil
Verapamil
Verapamil (USAN/INN)
Verapamil AL
Verapamil Acis
Verapamil Atid
Verapamil Basics
Verapamil Ebewe
Verapamil HCl
Verapamil Henning
Verapamil Hydrochloride
Verapamil Injection
Verapamil MSD
Verapamil NM
Verapamil NM Pharma
Verapamil Nordic
Verapamil PB
Verapamil Riker
Verapamil SR
Verapamil Verla
Verapamil [USAN:BAN:INN]
Verapamil [USAN:INN:BAN]
Verapamil [Usan:Ban:Inn]
Verapamil-AbZ
Verapamilo
Verapamilo [INN-Spanish]
Verapamilum
Verapamilum [INN-Latin]
Verapin
Verapress 240 SR
Veraptin
Verasal
Verasifar
Veratensin
Verdilac
Verelan
Verelan PM
Verelan Pm
Verelan SR
Verexamil
Veroptinstada
Verpamil
Vetrimil
Vortac
Vérapamil
alpha-((N-Methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
alpha-(3-((2-(3,4-Dimethoxyphenyl)ethyl)-methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)benzeneacetonitrile
alpha-Isopropyl-alpha-((N-methyl-N-homoveratryl)-gamma-aminopropyl)-3,4-dimethoxyphenylacetonitrile
cMAP_000023
delta-365
nchembio.368-comp2
nchembio.79-comp5
41
FurosemideapprovedPhase 4, Phase 315854-31-93440
Synonyms:
2-Furfurylamino-4-chloro-5-sulfamoylbenzoic acid
4-Chloro-5-sulfamoyl-N-furfuryl-anthranilic acid
4-Chloro-N-(2-furylmethyl)-5-sulfamoylanthranilic acid
4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid
4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoic acid
4-chloro-2-[(furan-2-ylmethyl)amino]-5-sulfamoylbenzoic acid
41733-55-5 (mono-hydrochloride salt)
5-18-09-00555 (Beilstein Handbook Reference)
54-31-9
AB00052001
AC-11067
AC1L1FXW
AC1Q557O
AKOS000266625
ARONIS24304
Acetic acid potassium salt
Aisemide
Aldalix
Aldic
Aluzine
Anfuramaide
Apo-Frusemide
Apo-Furosemide
Aquarid
Aquasin
Arasemide
BIDD:GT0139
BPBio1_000443
BRD-K78010432-001-05-8
BRN 0840915
BSPBio_000401
BSPBio_002054
Beronald
Bio-0044
Bioretic
Bristab
Bristurin
C12H11ClN2O5S
CAS-54-31-9
CCRIS 1951
CHEBI:47426
CHEMBL35
CID3440
CPD000058202
Cetasix
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure
Chlor-N-(2-furylmethyl)-5-sulfamylanthranilsaeure [German]
D00331
D005665
DB00695
DB07799
Depix
Desal
Desdemin
Di-Ademil
Dihydroflumethiazide
Dirine
Disal
Discoid
Disemide
Diucardin
Diumide-K
Diural
Diurapid
Diuretic Salt
Diuretic salt
Diurin
Diurolasa
Diusemide
Diusil
Diuzol
DivK1c_000575
Dranex
Dryptal
Durafurid
EINECS 200-203-6
Edemid
Edenol
Eliur
Elodrine
Endural
Errolon
Eutensin
F0182
F4381_SIGMA
FUN
FUROSEMIDE USP
Farsix
Finuret
Fluidrol
Fluss
Franyl
Frumex
Frumide
Frumil
Frusedan
Frusema
Frusemid
Frusemide
Frusemin
Frusenex
Frusetic
Frusid
Fu sid
Fulsix
Fuluvamide
Fuluvamine
Furanthril
Furanthryl
Furantral
Furantril
Furanturil
Furesis
Furetic
Furex
Furfan
Furix
Furmid
Furo-Basan
Furo-Puren
Furo-puren
Furobeta
Furocot
Furodiurol
Furodrix
Furomen
Furomex
Furomide M.D
Furomide M.D.
Furorese
Furosan
Furose
Furosedon
Furosemid
Furosemida
Furosemida [INN-Spanish]
Furosemide
Furosemide "mita"
Furosemide (JP15/USP/INN)
Furosemide Monohydrochloride
Furosemide Monosodium Salt
Furosemide [USAN:INN:JAN]
Furosemidu
Furosemidu [Polish]
Furosemidum
Furosemidum [INN-Latin]
Furosemix
Furoside
Furosifar
Furosix
Furoter
Furovite
Fursemid
Fursemida
Fursemide
Fursol
Fusid
Fusidic acid
 
Golan
HMS1569E03
HMS1920B03
HMS2090K06
HMS2091H05
HMS501M17
HSDB 3086
Hissuflux
Hoe-058A
Hydol
Hydrenox
Hydrex
Hydro
Hydro-Rapid
Hydro-rapid
Hydroled
I04-0179
IDI1_000575
Impugan
Jenafusid
KBio1_000575
KBio2_001580
KBio2_004148
KBio2_006716
KBio3_001274
KBioGR_001259
KBioSS_001580
Katlex
Kofuzon
Kolkin
Kutrix
LB 502
LB-502
LS-204
Lasemid
Lasex
Lasiletten
Lasilix
Lasix
Lasix (TN)
Lasix (tn)
Lasix Retard
Lasix Special
Lasix, Frusemide, Furosemide
Laxur
Lazix
Leodrine
Less Diur
Liside
Logirene
Lowpston
Lowpstron
Luscek
MLS001066374
MLS001306403
Macasirool
Marsemide
Metflorylthiazidine
Methforylthiazidine
Mirfat
Mita
Moilarorin
MolPort-001-641-065
Myrosemide
NCGC00016241-01
NCGC00090893-01
NCGC00090893-02
NCGC00090893-03
NCGC00090893-05
NCGC00090893-06
NCI-C55936
NINDS_000575
NSC 269420
NSC269420
Nadis
Nelsix
Neo-Renal
Neo-renal
Nephron
Nicorol
Novosemide
Octan Draselny
Octan draselny
Odemase
Odemex
Oedemex
Olmagran
Oprea1_667724
Osyrol
Polysquall A
Prefemin
Prestwick0_000341
Prestwick1_000341
Prestwick2_000341
Prestwick3_000341
Prestwick_752
Profemin
Promedes
Promide
Protargen
Puresis
Radisemide
Radonna
Radouna
Retep
Rodiuran
Rontyl
Rosemide
Rosis
Rusyde
S1603_Selleck
SAM002264614
SMP1_000129
SMR000058202
SPBio_001129
SPBio_002322
SPECTRUM1500310
STK177334
Sal Diureticum
Sal diureticum
Salinex
Salix
Salix (brand of furosemide)
Salurex
Salurid
Saluron
Seguril
Selectofur
Sigasalur
Sisuril
Spectrum2_001005
Spectrum3_000437
Spectrum4_000560
Spectrum5_000744
Spectrum_001100
Spirofur
Synephron
TL8003563
Transit
Trofurit
UNII-7LXU5N7ZO5
UPCMLD-DP022
UPCMLD-DP022:001
Uremide
Uresix
Urex
Urex-M
Urian
Uridon
Uritol
Urosemide
Vergonil
Vesix
WLN: T5OJ B1MR CG FVQ DSZW
Yidoli
Zafimida
fulvamide
furosemide
furosemide ''mita''
less Diur
42
Trastuzumabapproved, investigationalPhase 4688180288-69-19903
Synonyms:
180288-69-1
Anti HER2
Anti-erbB2 Monoclonal Antibody
D03257
HER2 Monoclonal Antibody
Herceptin
 
Herceptin (TN)
Ig gamma-1 chain C region
Trastuzumab
Trastuzumab (INN)
Trastuzumab (genetical recombination)
Trastuzumab (genetical recombination) (JAN)
trastuzumab
43
Clopidogrelapproved, nutraceuticalPhase 4, Phase 3674120202-66-6, 113665-84-260606
Synonyms:
( )-(S)-Clopidogrel
(+)-(S)-Clopidogrel
(+)-Clopidogrel
(S)-Clopidogrel
(S)-Methyl 2-(2-chlorophenyl)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
113665-84-2
AC-19024
AC1L1TKZ
AC1Q41I9
BIDD:GT0284
BRD-K27721098-065-02-9
BSPBio_003211
C16H16ClNO2S
CGE
CHEBI:37941
CHEMBL1771
CID60606
CLOPIDOGREL SULFATE
CPD000550475
Clopidogrel
Clopidogrel (INN)
Clopidogrel (TN)
Clopidogrel Bisulfate
Clopidogrel [BAN:INN]
Clopidogrel [Ban:Inn]
Clopidogrel [INN:BAN]
Clopidogrel bisulfate
Clopidogrel bisulphate
Clopidogrel sulfate
Clopidogrelum
D07729
DB00758
DivK1c_000787
HMS2090O21
HMS502H09
HSDB 7430
 
IDI1_000787
Isocover
KBio1_000787
KBio2_000545
KBio2_003113
KBio2_005681
KBio3_002431
KBioGR_000689
KBioSS_000545
LS-172232
MLS001165708
MLS001195633
MLS001304711
Methyl (+)-(S)-alpha-(o-chlorophenyl)-6,7-dihydrothieno(3,2-c)pyridine-5(4H)-acetate
MolPort-002-885-817
MolPort-003-845-991
NCGC00163329-02
NINDS_000787
Plavix
Plavix (TN)
SAM002589956
SMR000550475
SPBio_000463
SR 25990
STK580572
STOCK5S-27782
Spectrum2_000512
Spectrum3_001606
Spectrum4_000175
Spectrum_000105
TL8000400
UNII-A74586SNO7
Zyllt
clopidogrel
clopidogrel, (+)(S)-isomer
methyl (2S)-(2-chlorophenyl)(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethanoate
methyl (2S)-2-(2-chlorophenyl)-2-(6,7-dihydro-4H-thieno[3,2-c]pyridin-5-yl)acetate
nchem.651-comp8
44
Folic Acidapproved, nutraceuticalPhase 4285159-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic Acid
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
 
Folsaeure
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
45
Uric Acidexperimental, investigationalPhase 411269-93-21175
Synonyms:
1H-Purine-2,6,8-triol
2,6,8-Trihydroxypurine
2,6,8-Trioxopurine
2,6,8-Trioxypurine
 
7,9-dihydro-1H-purine-2,6,8(3H)-trione
Lithate
Lithic acid
Purine-2,6,8(1H,3H,9H)-trione
Urate
Uric acid
46
Candesartan cilexetilPhase 4, Phase 3, Phase 2144145040-37-52540
Synonyms:
(+-)-1-Hydroxyethyl 2-ethoxy-1-(p-(o-1H-tetrazol-5-ylphenyl)benzyl)-7-benzimidazolecarboxylate, cyclohexyl carbonate (ester)
1-(cyclohexylocarbonyloxy)ethyl-2-ethoxy-1-(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)-1H-benzimidazole-7-carboxylate
1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
1-{[(cyclohexyloxy)carbonyl]oxy}ethyl 2-(ethyloxy)-1-{[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate
145040-37-5
1H-Benzimidazole-7-carboxylic acid, 2-ethoxy-1-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, 1-[[(cyclohexyloxy)carbonyl]oxy]ethyl ester
2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester
2-ethoxy-3-[2'-(1h-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3h-benzoimidazole-4-carboxylic acid 1-cyclohe
AC-204
AC1L1DWQ
ATACAND HCT
Almirall brand of candesartan cilexetil
Amias
Astra brand of candesartan cilexetil
AstraZeneca brand of candesartan cilexetil
Atacand
Atacand (TN)
BRD-A65671304-001-02-6
BSPBio_002691
C07709
C077793
C33H34N6O6
CHEBI:216349
CHEMBL1014
CID2540
Candesartan cilexetil
Candesartan cilexetil (JAN/USAN)
Candesartan cilexetil [USAN]
Candesartan hexetil
D00626
FT-0082579
H212/91
 
HMS1922J09
HMS2093E20
I06-0090
KBio2_002187
KBio2_004755
KBio2_007323
KBio3_001911
KBioGR_001607
KBioSS_002187
Kenzen
L006257
LS-32741
MolPort-003-666-552
NCGC00095123-01
NCGC00095123-02
NCGC00095123-03
Parapres
Promed brand of candesartan cilexetil
Racanda
SPBio_000349
SPECTRUM1504261
ST51052687
Spectrum2_000485
Spectrum3_000996
Spectrum4_001124
Spectrum5_001462
Spectrum_001707
TCV 116
TCV-116
TL8000995
Takeda brand of candesartan cilexetil
UNII-R85M2X0D68
candesartan cilexitil
47Phosphodiesterase 3 InhibitorsPhase 4, Phase 3, Phase 1, Phase 2111
48MineralocorticoidsPhase 4, Phase 3, Phase 2, Phase 1294
49insulinPhase 4, Phase 2, Phase 04069
50
EnalaprilatPhase 4, Phase 310476420-72-96917719
Synonyms:
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid
(2S)-1-[(2S)-2-[[(2S)-1-hydroxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]pyrrolidine-2-carboxylic acid dihydrate
1-((2S)-2-{[(1S)-1-CARBOXY-3-PHENYLPROPYL]AMINO}PROPANOYL)-L-PROLINE
1-(N-((S)-1-Carboxy-3-phenylpropyl)-L-alanyl)-L-proline dihydrate
76420-72-9
AC1NUWEA
AC1OCEK7
BIDD:GT0752
C11720
C18H24N2O5.2H2O
CHEBI:116759
CHEBI:42302
CHEBI:4786
CHEBI:59877
CHEMBL1200697
CHEMBL577
CID5462501
CID6917719
CPD000466359
D03769
EAL
ENALAPRILAT INHIBITOR
Enalapril acid
Enalapril diacid
 
Enalaprilat
Enalaprilat (USP)
Enalaprilat anhydrous
Enalaprilate
Enalaprilatum
Enalaprilic acid
Enalprilate hydrate
HMS2051H16
HMS2089P04
LS-118903
LS-187219
MK-422
MLS000759476
MLS001424138
MolPort-005-943-792
N-[(1S)-1-Carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline
N-[(1S)-1-carboxy-3-phenylpropyl]-L-alanyl-L-proline--water (1/2)
NCGC00164593-01
S1657_Selleck
SAM001246684
SBB065733
SMR000466359
Vasotec I.V.
enalprilat hydrate

Interventional clinical trials:

(show top 50)    (show all 816)
idNameStatusNCT IDPhase
1Coenzyme Q10 Supplementation in Children With Idiopathic Dilated CardiomyopathyCompletedNCT02115581Phase 4
2A Randomized Trial of Carvedilol in Chronic Chagas CardiomyopathyCompletedNCT01557140Phase 4
3Statin Therapy for Ischemic and Nonischemic CardiomyopathyCompletedNCT00701220Phase 4
4Supramaximal Titrated Inhibition of RAAS in Dilated CardiomyopathyCompletedNCT01917149Phase 4
5Exercise Training in Chagas CardiomyopathyCompletedNCT01006473Phase 4
6Ranolazine in Ischemic CardiomyopathyCompletedNCT01345188Phase 4
7Chronic, Low Dose Erythropoetin Beta in Ischemic CardiomyopathyCompletedNCT00568542Phase 4
8Sympathetic Heart Innervation in Patients With Tako-Tsubo CardiomyopathyCompletedNCT01524861Phase 4
9Aspirin Withdrawal in Non-ischaemic Cardiomyopathy StudyCompletedNCT01534026Phase 4
10Effect of Beta-blockers on Structural Remodeling and Gene Expression in the Failing Human HeartCompletedNCT01798992Phase 4
11PACMAN - PAcing for CardioMyopathies, a EuropeAN StudyCompletedNCT00180596Phase 4
12Spironolactone Against Anthracycline-induced CardiomyopathyCompletedNCT02053974Phase 4
13Impact of Nesiritide Infusion for Decompensated Heart Failure in the Emergency DepartmentCompletedNCT00559338Phase 4
14Clinical Evaluation on Advanced ResynchronizationCompletedNCT00658203Phase 4
15Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs AloneCompletedNCT00391846Phase 4
16Spanish Atrial Fibrillation And Resynchronization StudyCompletedNCT01181414Phase 4
17ACC - Atrial Contribution to CRTCompletedNCT00180323Phase 4
18123-I mIBG (AdreView) Heart-to-Mediastinal (H/M) Ratio and SPECT Imaging on a Small Field of View-High Efficiency Cardiac SPECT SystemCompletedNCT01868841Phase 4
19Mechanisms of Improvement With Beta-Blocker Treatment in Heart FailureCompletedNCT01261065Phase 4
20Myocardial Glucose Uptake (MGU) in Patients With Chronic Kidney DiseaseCompletedNCT00883415Phase 4
21Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia MajorCompletedNCT00800761Phase 4
22Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS)CompletedNCT00371891Phase 4
23Prevention of CHOP-induced Chronic CardiotoxicityCompletedNCT00162955Phase 4
24Effects of Allopurinol on Diastolic Function in Chronic Heart Failure PatientsCompletedNCT00477789Phase 4
25Effects of Early Statin Treatment After Acute Myocardial Infarction (AMI) in Japanese PatientsCompletedNCT00128024Phase 4
26Cardiovascular Effects of Chronic Sildenafil in Men With Type 2 DiabetesCompletedNCT00692237Phase 4
27Substudy on the Mechanistic Plausibility of the Clinical Benefits of Adaptive Servo-ventilationCompletedNCT01164592Phase 4
28Statin Therapy in Heart Failure: Potential Mechanisms of BenefitCompletedNCT00233480Phase 4
29Sleep Apnea-hypopnea Syndrome (SAHS) and Ventricular ArrhythmiasCompletedNCT00765713Phase 4
30Myocardial Protection and Anesthetic AgentsCompletedNCT02405689Phase 4
31Sevoflurane and Isoflurane - During Cardiopulmonary Bypass With the MECC System (Minimized Extracorporeal Circuit)CompletedNCT01601795Phase 4
32ACCEL-LOADING-ACS StudyCompletedNCT01354808Phase 4
33Assessment of Wall Thickness in Hypertrophic CardiomyopathyRecruitingNCT02234336Phase 4
34Carvedilol Versus Verapamil in Chronic Heart Failure Secondary to Non-Ischemic CardiomyopathyRecruitingNCT00348530Phase 4
35CMR to Assess Fibrosis in Cardiomyopathy Using EplerenoneRecruitingNCT00401856Phase 4
36Multicenter Study of Immunoadsorption in Dilated CardiomyopathyRecruitingNCT00558584Phase 4
37Effects of Levosimendan and Milrinone on Left and Right Ventricular Function in Septic CardiomyopathyRecruitingNCT02640846Phase 4
38Clinical and Therapeutic Implications of Fibrosis in Hypertrophic CardiomyopathyRecruitingNCT00879060Phase 4
39Study of Qiliqiangxin Capsule to Treat Dilated CardiomyopathyRecruitingNCT01293903Phase 4
40Therapy With Verapamil or Carvedilol in Chronic Heart FailureRecruitingNCT00374465Phase 4
41REmodelling in Diabetic CardiOmapathy: Gender Response to PDE5i InhibiTOrsRecruitingNCT01803828Phase 4
42Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise CapacityRecruitingNCT00326690Phase 4
43The Preventive Efficacy of Carvedilol on Cardiac Dysfunction in Duchenne Muscular DystrophyRecruitingNCT00606775Phase 4
44IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF)RecruitingNCT01288560Phase 4
45Evaluation of Efficacy and Safety of Agalsidase Beta in Heterozygous Females for Fabry DiseaseRecruitingNCT00487630Phase 4
46(MitraClip in Non-Responders to Cardiac Resynchronization Therapy)RecruitingNCT02592889Phase 4
47AdaptResponse Clinical TrialRecruitingNCT02205359Phase 4
48Pilot Study of Ferric Carboxymaltose to Treat Iron Deficiency in Asians With Heart FailureRecruitingNCT01922479Phase 4
49Effects of Spironolactone in DialysisRecruitingNCT01128101Phase 4
50Regression of Fatty Heart by Valsartan TherapyRecruitingNCT00745953Phase 4

Search NIH Clinical Center for Noonan Syndrome 1


Cochrane evidence based reviews: Noonan Syndrome

Genetic Tests for Noonan Syndrome 1

About this section

Genetic tests related to Noonan Syndrome 1:

id Genetic test Affiliating Genes
1 Noonan Syndrome22 SOS1
2 Noonan Syndrome 124
3 Noonan's Syndrome24

Anatomical Context for Noonan Syndrome 1

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MalaCards organs/tissues related to Noonan Syndrome 1:

33
Heart, Skin, Testes, Spleen, Eye, Bone, Liver

Animal Models for Noonan Syndrome 1 or affiliated genes

About this section

MGI Mouse Phenotypes related to Noonan Syndrome 1:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000301210.3MYH7, NRAS, PTPN11, RAF1, RBM20, SOS1
2MP:000287310.1BRAF, KRAS, MYL2, NRAS, PTPN11, RAF1
3MP:000536910.1BRAF, KRAS, MYL2, PTPN11, RAF1, SOS1
4MP:000539110.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
5MP:000538010.0BRAF, KRAS, MYL2, NRAS, PTPN11, RAF1
6MP:00053859.8BRAF, KRAS, MYL2, NRAS, PTPN11, RAF1
7MP:00107689.6BRAF, DSG2, KRAS, LZTR1, MYL2, NRAS

Publications for Noonan Syndrome 1

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Variations for Noonan Syndrome 1

About this section

UniProtKB/Swiss-Prot genetic disease variations for Noonan Syndrome 1:

67 (show all 33)
id Symbol AA change Variation ID SNP ID
1PTPN11p.Thr42AlaVAR_015601
2PTPN11p.Gly60AlaVAR_015602
3PTPN11p.Asp61GlyVAR_015603
4PTPN11p.Asp61AsnVAR_015604
5PTPN11p.Tyr62AspVAR_015605
6PTPN11p.Tyr63CysVAR_015606
7PTPN11p.Ala72GlyVAR_015607
8PTPN11p.Ala72SerVAR_015608
9PTPN11p.Thr73IleVAR_015609rs28933387
10PTPN11p.Glu76AspVAR_015610
11PTPN11p.Gln79ArgVAR_015611
12PTPN11p.Asp106AlaVAR_015612
13PTPN11p.Glu139AspVAR_015613
14PTPN11p.Tyr279CysVAR_015614
15PTPN11p.Ile282ValVAR_015615
16PTPN11p.Phe285SerVAR_015616
17PTPN11p.Phe285LeuVAR_015617
18PTPN11p.Asn308SerVAR_015618
19PTPN11p.Asn308AspVAR_015619
20PTPN11p.Arg505LysVAR_015622
21PTPN11p.Ser506ThrVAR_015623
22PTPN11p.Met508ValVAR_015624
23PTPN11p.Gly507ArgVAR_016003
24PTPN11p.Thr2IleVAR_027183
25PTPN11p.Asn58LysVAR_027184
26PTPN11p.Glu69GlnVAR_027185
27PTPN11p.Gln79ProVAR_027186
28PTPN11p.Gln256ArgVAR_027187
29PTPN11p.Thr415MetVAR_027189
30PTPN11p.Gln510ArgVAR_027195
31PTPN11p.Leu564PheVAR_027197
32PTPN11p.Thr59AlaVAR_066060
33PTPN11p.Pro495SerVAR_071706

Clinvar genetic disease variations for Noonan Syndrome 1:

5 (show all 407)
id Gene Variation Type Significance SNP ID Assembly Location
1RAF1NM_002880.3(RAF1): c.782C> T (p.Pro261Leu)single nucleotide variantPathogenicrs397516828GRCh38Chr 3, 12604188: 12604188
2TNNT2NM_001001430.2(TNNT2): c.236T> A (p.Ile79Asn)single nucleotide variantLikely pathogenic, Pathogenicrs121964855GRCh37Chr 1, 201334766: 201334766
3TNNT2NM_001001430.2(TNNT2): c.275G> A (p.Arg92Gln)single nucleotide variantPathogenicrs121964856GRCh37Chr 1, 201334425: 201334425
4TNNT2NM_000364.3(TNNT2): c.853C> T (p.Arg285Cys)single nucleotide variantLikely pathogenic, Pathogenicrs121964857GRCh37Chr 1, 201328373: 201328373
5TNNT2NM_000364.3(TNNT2): c.451C> T (p.Arg151Trp)single nucleotide variantLikely pathogenic, Pathogenicrs74315379GRCh37Chr 1, 201333464: 201333464
6TNNT2NM_001001430.2(TNNT2): c.391C> T (p.Arg131Trp)single nucleotide variantLikely pathogenic, Pathogenicrs74315380GRCh37Chr 1, 201333494: 201333494
7TNNI3NM_000363.4(TNNI3): c.586G> A (p.Asp196Asn)single nucleotide variantLikely pathogenic, Pathogenicrs104894727GRCh37Chr 19, 55663249: 55663249
8TNNI3NM_000363.4(TNNI3): c.575G> A (p.Arg192His)single nucleotide variantLikely pathogenic, Pathogenicrs104894729GRCh37Chr 19, 55663260: 55663260
9TNNI3NM_000363.4(TNNI3): c.433C> T (p.Arg145Trp)single nucleotide variantLikely pathogenic, Pathogenicrs104894724GRCh37Chr 19, 55665514: 55665514
10TNNC1NM_003280.2(TNNC1): c.23C> T (p.Ala8Val)single nucleotide variantPathogenicrs267607125GRCh37Chr 3, 52488009: 52488009
11TNNC1NM_003280.2(TNNC1): c.435C> A (p.Asp145Glu)single nucleotide variantPathogenicrs267607124GRCh37Chr 3, 52485426: 52485426
12TPM1NM_001018005.1(TPM1): c.539A> G (p.Glu180Gly)single nucleotide variantPathogenicrs104894502GRCh37Chr 15, 63353114: 63353114
13TPM1NM_001018005.1(TPM1): c.523G> A (p.Asp175Asn)single nucleotide variantPathogenicrs104894503GRCh37Chr 15, 63353098: 63353098
14TPM1NM_001018005.1(TPM1): c.284T> C (p.Val95Ala)single nucleotide variantPathogenicrs104894504GRCh37Chr 15, 63349227: 63349227
15TPM1NM_001018005.1(TPM1): c.160G> A (p.Glu54Lys)single nucleotide variantPathogenicrs104894505GRCh37Chr 15, 63336271: 63336271
16KRASNM_004985.4(KRAS): c.455T> G (p.Val152Gly)single nucleotide variantPathogenicrs104894367GRCh37Chr 12, 25362841: 25362841
17TNNT2NM_001001430.2(TNNT2): c.400C> T (p.Arg134Trp)single nucleotide variantPathogenicrs45525839GRCh37Chr 1, 201333485: 201333485
18SOS1NM_005633.3(SOS1): c.797C> A (p.Thr266Lys)single nucleotide variantPathogenicrs137852812GRCh37Chr 2, 39278352: 39278352
19SOS1NM_005633.3(SOS1): c.1654A> G (p.Arg552Gly)single nucleotide variantPathogenicrs137852814GRCh37Chr 2, 39249915: 39249915
20SOS1NM_005633.3(SOS1): c.1656G> C (p.Arg552Ser)single nucleotide variantPathogenicrs267607079GRCh37Chr 2, 39249913: 39249913
21TNNT2NM_001001430.2(TNNT2): c.430C> T (p.Arg144Trp)single nucleotide variantPathogenicrs483352832GRCh37Chr 1, 201333455: 201333455
22PTPN11NM_002834.3(PTPN11): c.214G> T (p.Ala72Ser)single nucleotide variantPathogenicrs121918453GRCh37Chr 12, 112888198: 112888198
23PTPN11NM_002834.3(PTPN11): c.215C> G (p.Ala72Gly)single nucleotide variantPathogenicrs121918454GRCh37Chr 12, 112888199: 112888199
24PTPN11NM_002834.3(PTPN11): c.922A> G (p.Asn308Asp)single nucleotide variantPathogenicrs28933386GRCh37Chr 12, 112915523: 112915523
25PTPN11NM_002834.3(PTPN11): c.923A> G (p.Asn308Ser)single nucleotide variantPathogenicrs121918455GRCh37Chr 12, 112915524: 112915524
26PTPN11NM_002834.3(PTPN11): c.836A> G (p.Tyr279Cys)single nucleotide variantPathogenicrs121918456GRCh37Chr 12, 112910827: 112910827
27PTPN11NM_002834.3(PTPN11): c.184T> G (p.Tyr62Asp)single nucleotide variantPathogenicrs121918460GRCh37Chr 12, 112888168: 112888168
28PTPN11NM_002834.3(PTPN11): c.182A> G (p.Asp61Gly)single nucleotide variantPathogenicrs121918461GRCh37Chr 12, 112888166: 112888166
29PTPN11NM_002834.3(PTPN11): c.1403C> T (p.Thr468Met)single nucleotide variantPathogenicrs121918457GRCh37Chr 12, 112926270: 112926270
30PTPN11NM_002834.3(PTPN11): c.1504T> A (p.Ser502Thr)single nucleotide variantPathogenicrs121918458GRCh37Chr 12, 112926884: 112926884
31PTPN11NM_002834.3(PTPN11): c.188A> G (p.Tyr63Cys)single nucleotide variantPathogenicrs121918459GRCh37Chr 12, 112888172: 112888172
32PTPN11NM_002834.3(PTPN11): c.218C> T (p.Thr73Ile)single nucleotide variantPathogenicrs121918462GRCh37Chr 12, 112888202: 112888202
33PTPN11NM_002834.3(PTPN11): c.854T> C (p.Phe285Ser)single nucleotide variantPathogenicrs121918463GRCh37Chr 12, 112915455: 112915455
34PTPN11NM_002834.3(PTPN11): c.226G> A (p.Glu76Lys)single nucleotide variantPathogenicrs121918464GRCh37Chr 12, 112888210: 112888210
35PTPN11NM_002834.3(PTPN11): c.227A> G (p.Glu76Gly)single nucleotide variantLikely pathogenic, Pathogenicrs121918465GRCh37Chr 12, 112888211: 112888211
36PTPN11NM_002834.3(PTPN11): c.236A> G (p.Gln79Arg)single nucleotide variantPathogenicrs121918466GRCh37Chr 12, 112888220: 112888220
37PTPN11NM_002834.3(PTPN11): c.1232C> T (p.Thr411Met)single nucleotide variantPathogenicrs121918467GRCh37Chr 12, 112924286: 112924286
38PTPN11NM_002834.3(PTPN11): c.1381G> A (p.Ala461Thr)single nucleotide variantPathogenicrs121918468GRCh37Chr 12, 112926248: 112926248
39PTPN11NM_002834.3(PTPN11): c.1391G> C (p.Gly464Ala)single nucleotide variantPathogenicrs121918469GRCh37Chr 12, 112926258: 112926258
40PTPN11NM_002834.3(PTPN11): c.1529A> C (p.Gln510Pro)single nucleotide variantPathogenicrs121918470GRCh37Chr 12, 112926909: 112926909
41PTPN11NM_002834.3(PTPN11): c.1529A> G (p.Gln510Arg)single nucleotide variantPathogenicrs121918470GRCh37Chr 12, 112926909: 112926909
42PTPN11NM_002834.3(PTPN11): c.179_181delGTG (p.Gly60del)deletionPathogenicrs80338836GRCh37Chr 12, 112888163: 112888165
43PTPN11NM_002834.3(PTPN11): c.5C> T (p.Thr2Ile)single nucleotide variantPathogenicrs267606990GRCh37Chr 12, 112856920: 112856920
44TTRNM_000371.3(TTR): c.148G> A (p.Val50Met)single nucleotide variantPathogenicrs28933979GRCh37Chr 18, 29172937: 29172937
45TTRNM_000371.3(TTR): c.233T> A (p.Leu78His)single nucleotide variantPathogenicrs121918069GRCh37Chr 18, 29175115: 29175115
46TTRNM_000371.3(TTR): c.238A> G (p.Thr80Ala)single nucleotide variantPathogenicrs121918070GRCh37Chr 18, 29175120: 29175120
47TTRNM_000371.3(TTR): c.424G> A (p.Val142Ile)single nucleotide variantPathogenicrs76992529GRCh37Chr 18, 29178618: 29178618
48TTRNM_000371.3(TTR): c.88T> C (p.Cys30Arg)single nucleotide variantPathogenicrs121918083GRCh37Chr 18, 29172877: 29172877
49TTRNM_000371.3(TTR): c.118G> A (p.Val40Ile)single nucleotide variantPathogenicrs121918093GRCh37Chr 18, 29172907: 29172907
50NM_002667.3(PLN): c.25C> T (p.Arg9Cys)single nucleotide variantPathogenicrs111033559GRCh37Chr 6, 118880109: 118880109
51NRASNM_002524.4(NRAS): c.149C> T (p.Thr50Ile)single nucleotide variantPathogenicrs267606921GRCh37Chr 1, 115256562: 115256562
52RAF1NM_002880.3(RAF1): c.770C> T (p.Ser257Leu)single nucleotide variantPathogenicrs80338796GRCh37Chr 3, 12645699: 12645699
53RAF1NM_002880.3(RAF1): c.1472C> G (p.Thr491Arg)single nucleotide variantPathogenicrs80338799GRCh37Chr 3, 12627244: 12627244
54MYL3NM_000258.2(MYL3): c.445A> G (p.Met149Val)single nucleotide variantPathogenicrs104893748GRCh37Chr 3, 46901001: 46901001
55MYL3NM_000258.2(MYL3): c.427G> A (p.Glu143Lys)single nucleotide variantPathogenicrs104893750GRCh37Chr 3, 46901019: 46901019
56MYL2NM_000432.3(MYL2): c.37G> A (p.Ala13Thr)single nucleotide variantLikely pathogenic, Pathogenicrs104894363GRCh37Chr 12, 111356964: 111356964
57MYL2NM_000432.3(MYL2): c.64G> A (p.Glu22Lys)single nucleotide variantLikely pathogenic, Pathogenicrs104894368GRCh37Chr 12, 111356937: 111356937
58MYL2NM_000432.3(MYL2): c.173G> A (p.Arg58Gln)single nucleotide variantPathogenicrs104894369GRCh37Chr 12, 111352091: 111352091
59MYH7NM_000257.3(MYH7): c.1208G> A (p.Arg403Gln)single nucleotide variantPathogenicrs121913624GRCh37Chr 14, 23898487: 23898487
60MYH7NM_000257.3(MYH7): c.746G> A (p.Arg249Gln)single nucleotide variantLikely pathogenic, Pathogenicrs3218713GRCh37Chr 14, 23900677: 23900677
61MYH7NM_000257.3(MYH7): c.1357C> T (p.Arg453Cys)single nucleotide variantLikely pathogenic, Pathogenicrs121913625GRCh37Chr 14, 23898214: 23898214
62MYH7NM_000257.3(MYH7): c.1750G> C (p.Gly584Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121913626GRCh37Chr 14, 23896932: 23896932
63MYH7NM_000257.3(MYH7): c.1816G> A (p.Val606Met)single nucleotide variantLikely pathogenic, Pathogenicrs121913627GRCh37Chr 14, 23896866: 23896866
64MYH7NM_000257.3(MYH7): c.2770G> A (p.Glu924Lys)single nucleotide variantLikely pathogenic, Pathogenicrs121913628GRCh37Chr 14, 23893268: 23893268
65MYH7NM_000257.3(MYH7): c.1046T> C (p.Met349Thr)single nucleotide variantPathogenicrs121913640GRCh37Chr 14, 23899076: 23899076
66MYH7NM_000257.3(MYH7): c.2167C> T (p.Arg723Cys)single nucleotide variantLikely pathogenic, Pathogenicrs121913630GRCh37Chr 14, 23895023: 23895023
67MYH7NM_000257.3(MYH7): c.2722C> G (p.Leu908Val)single nucleotide variantLikely pathogenic, Pathogenicrs121913631GRCh37Chr 14, 23893316: 23893316
68MYH7NM_000257.3(MYH7): c.2221G> C (p.Gly741Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121913632GRCh37Chr 14, 23894969: 23894969
69MYH7NM_000257.3(MYH7): c.767G> A (p.Gly256Glu)single nucleotide variantPathogenicrs121913633GRCh37Chr 14, 23900656: 23900656
70MYH7NM_000257.3(MYH7): c.1208G> T (p.Arg403Leu)single nucleotide variantPathogenicrs121913624GRCh37Chr 14, 23898487: 23898487
71MYH7NM_000257.3(MYH7): c.1207C> T (p.Arg403Trp)single nucleotide variantLikely pathogenic, Pathogenicrs3218714GRCh37Chr 14, 23898488: 23898488
72MYH7NM_000257.3(MYH7): c.2155C> T (p.Arg719Trp)single nucleotide variantPathogenicrs121913637GRCh37Chr 14, 23895180: 23895180
73MYH7NM_000257.3(MYH7): c.2146G> A (p.Gly716Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121913638GRCh37Chr 14, 23895189: 23895189
74MYH7NM_000257.3(MYH7): c.2156G> A (p.Arg719Gln)single nucleotide variantLikely pathogenic, Pathogenicrs121913641GRCh37Chr 14, 23895179: 23895179
75MYH7NM_000257.3(MYH7): c.2609G> A (p.Arg870His)single nucleotide variantLikely pathogenic, Pathogenicrs36211715GRCh37Chr 14, 23894048: 23894048
76MYH7NM_000257.3(MYH7): c.5647G> A (p.Glu1883Lys)single nucleotide variantPathogenicrs121913652GRCh37Chr 14, 23883224: 23883224
77MYH7NM_000257.3(MYH7): c.5378T> C (p.Leu1793Pro)single nucleotide variantPathogenicrs121913654GRCh37Chr 14, 23884385: 23884385
78MYH7NM_000257.3(MYH7): c.1491G> T (p.Glu497Asp)single nucleotide variantLikely pathogenic, Pathogenicrs267606911GRCh37Chr 14, 23897796: 23897796
79MYH7NM_000257.3(MYH7): c.2717A> G (p.Asp906Gly)single nucleotide variantPathogenicrs267606908GRCh37Chr 14, 23893321: 23893321
80MYH7NM_000257.3(MYH7): c.728G> A (p.Arg243His)single nucleotide variantPathogenicrs267606910GRCh37Chr 14, 23900798: 23900798
81MYBPC3NM_000256.3(MYBPC3): c.3190+5G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs587782958GRCh38Chr 11, 47333552: 47333552
82MYH7NM_000257.3(MYH7): c.3158G> A (p.Arg1053Gln)single nucleotide variantPathogenicrs587782962GRCh37Chr 14, 23891476: 23891476
83DSG2NM_001943.3(DSG2): c.1912G> A (p.Gly638Arg)single nucleotide variantPathogenicrs201564919GRCh37Chr 18, 29121188: 29121188
84MYBPC3NM_000256.3(MYBPC3): c.13G> C (p.Gly5Arg)single nucleotide variantLikely pathogenic, Pathogenicrs201278114GRCh37Chr 11, 47374186: 47374186
85MYBPC3NM_000256.3(MYBPC3): c.2311G> A (p.Val771Met)single nucleotide variantPathogenicrs371488302GRCh37Chr 11, 47359343: 47359343
86MYBPC3NM_000256.3(MYBPC3): c.961G> A (p.Val321Met)single nucleotide variantPathogenicrs200119454GRCh37Chr 11, 47367887: 47367887
87MYH7NM_000257.3(MYH7): c.5561C> T (p.Thr1854Met)single nucleotide variantPathogenicrs372381770GRCh37Chr 14, 23883310: 23883310
88MYH7NM_000257.3(MYH7): c.5305C> A (p.Leu1769Met)single nucleotide variantPathogenicrs139222507GRCh37Chr 14, 23884458: 23884458
89MYH7NM_000257.3(MYH7): c.3301G> A (p.Gly1101Ser)single nucleotide variantPathogenicrs367546859GRCh37Chr 14, 23890202: 23890202
90MYH7NM_000257.3(MYH7): c.2608C> T (p.Arg870Cys)single nucleotide variantLikely pathogenic, Pathogenicrs138049878GRCh37Chr 14, 23894049: 23894049
91MYH7NM_000257.3(MYH7): c.2359C> T (p.Arg787Cys)single nucleotide variantLikely pathogenic, Pathogenicrs145677314GRCh37Chr 14, 23894555: 23894555
92MYH7NM_000257.3(MYH7): c.958G> A (p.Val320Met)single nucleotide variantLikely pathogenic, Pathogenicrs376897125GRCh37Chr 14, 23899810: 23899810
93TNNI3NM_000363.4(TNNI3): c.484C> T (p.Arg162Trp)single nucleotide variantLikely pathogenic, Pathogenicrs368861241GRCh37Chr 19, 55665463: 55665463
94MYBPC3NM_000256.3(MYBPC3): c.3642G> A (p.Trp1214Ter)single nucleotide variantLikely pathogenic, Pathogenicrs368765949GRCh37Chr 11, 47353795: 47353795
95BRAFNM_004333.4(BRAF): c.2135C> A (p.Ala712Asp)single nucleotide variantLikely pathogenicrs727502904GRCh37Chr 7, 140434563: 140434563
96KRASNM_004985.4(KRAS): c.466T> A (p.Phe156Ile)single nucleotide variantPathogenicrs397517042GRCh37Chr 12, 25362830: 25362830
97KRASNM_004985.4(KRAS): c.108A> G (p.Ile36Met)single nucleotide variantLikely pathogenicrs727503109GRCh37Chr 12, 25398211: 25398211
98MYBPC3NM_000256.3(MYBPC3): c.3776delA (p.Gln1259Argfs)deletionLikely pathogenic, Pathogenicrs727503166GRCh37Chr 11, 47353661: 47353661
99MYBPC3NM_000256.3(MYBPC3): c.3288delG (p.Glu1096Aspfs)deletionPathogenicrs727503172GRCh37Chr 11, 47354787: 47354787
100MYBPC3NM_000256.3(MYBPC3): c.2875_2876delAC (p.Thr959Glyfs)deletionPathogenicrs727503182GRCh37Chr 11, 47356622: 47356623
101MYBPC3NM_000256.3(MYBPC3): c.2556delC (p.Ile852Metfs)deletionPathogenicrs727503186GRCh37Chr 11, 47358988: 47358988
102MYBPC3NM_000256.3(MYBPC3): c.1999_2000delCTinsG (p.Leu667Aspfs)indelPathogenicrs727503192GRCh37Chr 11, 47361269: 47361270
103MYBPC3NM_000256.3(MYBPC3): c.1790G> A (p.Arg597Gln)single nucleotide variantLikely pathogenic, Pathogenicrs727503195GRCh37Chr 11, 47363542: 47363542
104MYBPC3NM_000256.3(MYBPC3): c.1624+2T> Csingle nucleotide variantPathogenicrs111437311GRCh37Chr 11, 47364127: 47364127
105MYBPC3NM_000256.3(MYBPC3): c.1591G> A (p.Gly531Arg)single nucleotide variantLikely pathogenic, Pathogenicrs397515912GRCh37Chr 11, 47364162: 47364162
106MYBPC3NM_000256.3(MYBPC3): c.1484G> A (p.Arg495Gln)single nucleotide variantLikely pathogenic, Pathogenicrs200411226GRCh37Chr 11, 47364269: 47364269
107MYBPC3NM_000256.3(MYBPC3): c.833delG (p.Gly278Glufs)deletionPathogenicrs727503212GRCh37Chr 11, 47369220: 47369220
108MYH7NM_000257.3(MYH7): c.4066G> A (p.Glu1356Lys)single nucleotide variantLikely pathogenic, Pathogenicrs727503246GRCh37Chr 14, 23887522: 23887522
109MYH7NM_000257.3(MYH7): c.2788G> C (p.Glu930Gln)single nucleotide variantLikely pathogenic, Pathogenicrs397516171GRCh37Chr 14, 23893250: 23893250
110MYH7NM_000257.3(MYH7): c.2782G> A (p.Asp928Asn)single nucleotide variantLikely pathogenic, Pathogenicrs727503252GRCh37Chr 14, 23893256: 23893256
111MYH7NM_000257.3(MYH7): c.2710C> T (p.Arg904Cys)single nucleotide variantPathogenicrs727503253GRCh37Chr 14, 23893328: 23893328
112MYH7NM_000257.3(MYH7): c.2572C> T (p.Arg858Cys)single nucleotide variantLikely pathogenic, Pathogenicrs2754158GRCh37Chr 14, 23894085: 23894085
113MYH7NM_000257.3(MYH7): c.2302G> A (p.Gly768Arg)single nucleotide variantLikely pathogenic, Pathogenicrs727503260GRCh37Chr 14, 23894612: 23894612
114MYH7NM_000257.3(MYH7): c.2207T> C (p.Ile736Thr)single nucleotide variantLikely pathogenic, Pathogenicrs727503261GRCh38Chr 14, 23425774: 23425774
115MYH7NM_000257.3(MYH7): c.1012G> A (p.Val338Met)single nucleotide variantLikely pathogenic, Pathogenicrs727503271GRCh37Chr 14, 23899110: 23899110
116MYH7NM_000257.3(MYH7): c.427C> T (p.Arg143Trp)single nucleotide variantLikely pathogenic, Pathogenicrs727503278GRCh37Chr 14, 23901923: 23901923
117PTPN11NM_002834.3(PTPN11): c.598A> T (p.Asn200Tyr)single nucleotide variantLikely pathogenicrs727503381GRCh37Chr 12, 112892440: 112892440
118RAF1NM_002880.3(RAF1): c.285C> G (p.Cys95Trp)single nucleotide variantLikely pathogenicrs727503384GRCh37Chr 3, 12653484: 12653484
119TNNI3NM_000363.4(TNNI3): c.509G> A (p.Arg170Gln)single nucleotide variantPathogenicrs727503503GRCh37Chr 19, 55665438: 55665438
120TNNT2NM_001001430.2(TNNT2): c.280C> T (p.Arg94Cys)single nucleotide variantLikely pathogenic, Pathogenicrs727503513GRCh37Chr 1, 201334420: 201334420
121DSG2NM_001943.3(DSG2): c.146G> A (p.Arg49His)single nucleotide variantLikely pathogenic, Pathogenicrs121913006GRCh37Chr 18, 29099830: 29099830
122DSG2NM_001943.3(DSG2): c.918G> A (p.Trp306Ter)single nucleotide variantPathogenicrs121913007GRCh37Chr 18, 29104755: 29104755
123DSG2NM_001943.3(DSG2): c.137G> A (p.Arg46Gln)single nucleotide variantLikely pathogenic, Pathogenicrs121913008GRCh37Chr 18, 29099821: 29099821
124DSG2NM_001943.3(DSG2): c.1880-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs397514038GRCh37Chr 18, 29121154: 29121154
125DSG2NM_001943.3(DSG2): c.166G> A (p.Val56Met)single nucleotide variantPathogenic, risk factorrs121913013GRCh37Chr 18, 29099850: 29099850
126DSC2NM_024422.4(DSC2): c.631-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs397514042GRCh37Chr 18, 28667778: 28667778
127MYH7NM_000257.3(MYH7): c.1727A> G (p.His576Arg)single nucleotide variantLikely pathogenic, Pathogenicrs727504238GRCh37Chr 14, 23896955: 23896955
128MYH7NM_000257.3(MYH7): c.2080C> T (p.Arg694Cys)single nucleotide variantLikely pathogenic, Pathogenicrs727504240GRCh37Chr 14, 23895255: 23895255
129MYH7NM_000257.3(MYH7): c.5326A> G (p.Ser1776Gly)single nucleotide variantLikely pathogenic, Pathogenicrs369437262GRCh37Chr 14, 23884437: 23884437
130TNNI3NM_000363.4(TNNI3): c.610C> T (p.Arg204Cys)single nucleotide variantLikely pathogenic, Pathogenicrs727504243GRCh37Chr 19, 55663225: 55663225
131TNNT2NM_001001430.2(TNNT2): c.247G> A (p.Glu83Lys)single nucleotide variantLikely pathogenic, Pathogenicrs727504244GRCh37Chr 1, 201334755: 201334755
132TNNT2NM_001001430.2(TNNT2): c.311C> T (p.Ala104Val)single nucleotide variantLikely pathogenic, Pathogenicrs727504245GRCh37Chr 1, 201334389: 201334389
133TNNT2NM_001001430.2(TNNT2): c.860G> A (p.Trp287Ter)single nucleotide variantLikely pathogenic, Pathogenicrs727504247GRCh38Chr 1, 201359217: 201359217
134TNNT2NM_001001430.2(TNNT2): c.244G> A (p.Gly82Arg)single nucleotide variantLikely pathogenic, Pathogenicrs727504255GRCh37Chr 1, 201334758: 201334758
135MYBPC3NM_000256.3(MYBPC3): c.2780_2781delCA (p.Thr927Ilefs)deletionPathogenicrs727504265GRCh37Chr 11, 47356717: 47356718
136MYH7NM_000257.3(MYH7): c.2221G> T (p.Gly741Trp)single nucleotide variantLikely pathogenic, Pathogenicrs121913632GRCh37Chr 14, 23894969: 23894969
137MYH7NM_000257.3(MYH7): c.3346G> A (p.Glu1116Lys)single nucleotide variantLikely pathogenic, Pathogenicrs727504274GRCh37Chr 14, 23889434: 23889434
138MYH7NM_000257.3(MYH7): c.5329G> A (p.Ala1777Thr)single nucleotide variantLikely pathogenic, Pathogenicrs200939753GRCh37Chr 14, 23884434: 23884434
139MYBPC3NM_000256.3(MYBPC3): c.1038_1042dupCGGCA (p.Met348Thrfs)duplicationPathogenicrs730880336GRCh38Chr 11, 47346255: 47346259
140MYBPC3NM_000256.3(MYBPC3): c.1513_1515delAAG (p.Lys505del)deletionLikely pathogenic, Pathogenicrs727504287GRCh37Chr 11, 47364238: 47364240
141MYBPC3NM_000256.3(MYBPC3): c.2441_2443delAGA (p.Lys814del)deletionLikely pathogenic, Pathogenicrs727504288GRCh37Chr 11, 47359101: 47359103
142MYH7NM_000257.3(MYH7): c.2539A> G (p.Lys847Glu)single nucleotide variantLikely pathogenic, Pathogenicrs727504310GRCh37Chr 14, 23894118: 23894118
143TNNT2NM_001001430.2(TNNT2): c.330T> G (p.Phe110Leu)single nucleotide variantLikely pathogenic, Pathogenicrs727504331GRCh37Chr 1, 201334370: 201334370
144MYH7NM_000257.3(MYH7): c.3236G> A (p.Arg1079Gln)single nucleotide variantPathogenicrs727504342GRCh37Chr 14, 23891398: 23891398
145MYBPC3NM_000256.3(MYBPC3): c.3190+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs111683277GRCh37Chr 11, 47355107: 47355107
146BRAFNM_004333.4(BRAF): c.1449A> C (p.Lys483Asn)single nucleotide variantLikely pathogenicrs727504375GRCh37Chr 7, 140477859: 140477859
147MYH7NM_000257.3(MYH7): c.1324C> T (p.Arg442Cys)single nucleotide variantPathogenicrs148808089GRCh37Chr 14, 23898247: 23898247
148MYBPC3NM_000256.3(MYBPC3): c.1000G> A (p.Glu334Lys)single nucleotide variantLikely pathogenic, Pathogenicrs573916965GRCh37Chr 11, 47367848: 47367848
149KRASNM_004985.4(KRAS): c.214A> T (p.Met72Leu)single nucleotide variantPathogenicrs727504662GRCh37Chr 12, 25380244: 25380244
150PTPN11NM_002834.3(PTPN11): c.182A> C (p.Asp61Ala)single nucleotide variantLikely pathogenicrs121918461GRCh37Chr 12, 112888166: 112888166
151MYH7NM_000257.3(MYH7): c.2785G> A (p.Glu929Lys)single nucleotide variantPathogenicrs730880161GRCh38Chr 14, 23424044: 23424044
152NM_000257.3(MYH7): c.4499G> A (p.Arg1500Gln)single nucleotide variantLikely pathogenic, Pathogenicrs121913647GRCh37Chr 14, 23886382: 23886382
153MYH7NM_000257.3(MYH7): c.1888+1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs113186231GRCh37Chr 14, 23896793: 23896793
154TNNT2NM_001001430.2(TNNT2): c.613C> T (p.Arg205Trp)single nucleotide variantLikely pathogenic, Pathogenicrs45586240GRCh38Chr 1, 201361989: 201361989
155MYBPC3NM_000256.3(MYBPC3): c.1227-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs730880531GRCh38Chr 11, 47343147: 47343147
156MYBPC3NM_000256.3(MYBPC3): c.484C> T (p.Gln162Ter)single nucleotide variantPathogenicrs730880618GRCh38Chr 11, 47350035: 47350035
157MYBPC3NM_000256.3(MYBPC3): c.1838dupA (p.Asp613Glufs)duplicationPathogenicrs730880649GRCh37Chr 11, 47362748: 47362748
158MYH7NM_000257.3(MYH7): c.2191C> T (p.Pro731Ser)single nucleotide variantLikely pathogenic, Pathogenicrs727504299GRCh38Chr 14, 23425790: 23425790
159MYH7NM_000257.3(MYH7): c.5458C> T (p.Arg1820Trp)single nucleotide variantLikely pathogenic, Pathogenicrs145734640GRCh37Chr 14, 23884305: 23884305
160TNNI3NM_000363.4(TNNI3): c.596G> A (p.Ser199Asn)single nucleotide variantPathogenicrs730881091GRCh37Chr 19, 55663239: 55663239
161ACTN2NM_001103.3(ACTN2): c.26A> G (p.Gln9Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121434525GRCh37Chr 1, 236849999: 236849999
162NM_005159.4(ACTC1): c.889G> T (p.Ala297Ser)single nucleotide variantPathogenicrs121912675GRCh37Chr 15, 35083416: 35083416
163NM_005159.4(ACTC1): c.268C> T (p.His90Tyr)single nucleotide variantPathogenicrs121912676GRCh37Chr 15, 35085632: 35085632
164NM_005159.4(ACTC1): c.301G> A (p.Glu101Lys)single nucleotide variantLikely pathogenic, Pathogenicrs193922680GRCh37Chr 15, 35085599: 35085599
165RIT1RIT1, PHE82VALsingle nucleotide variantPathogenic
166RIT1RIT1, MET90ILEsingle nucleotide variantPathogenic
167LZTR1LZTR1, GLY248ARGundetermined variantPathogenic
168LZTR1NM_006767.3(LZTR1): c.850C> T (p.Arg284Cys)single nucleotide variantPathogenicrs797045165GRCh38Chr 22, 20991686: 20991686
169LZTR1NM_006767.3(LZTR1): c.740G> A (p.Ser247Asn)single nucleotide variantPathogenicrs797045166GRCh38Chr 22, 20990474: 20990474
170SOS2SOS2, THR376SERundetermined variantPathogenic
171SOS2NM_006939.2(SOS2): c.800T> A (p.Met267Lys)single nucleotide variantPathogenicrs797045167GRCh37Chr 14, 50649239: 50649239
172RBM20NM_001134363.2(RBM20): c.1913C> T (p.Pro638Leu)single nucleotide variantPathogenicrs267607003GRCh37Chr 10, 112572068: 112572068
173RBM20NM_001134363.2(RBM20): c.1901G> A (p.Arg634Gln)single nucleotide variantPathogenicrs267607001GRCh37Chr 10, 112572056: 112572056
174RBM20NM_001134363.2(RBM20): c.1906C> A (p.Arg636Ser)single nucleotide variantLikely pathogenic, Pathogenicrs267607002GRCh37Chr 10, 112572061: 112572061
175RBM20NM_001134363.2(RBM20): c.1907G> A (p.Arg636His)single nucleotide variantPathogenicrs267607004GRCh37Chr 10, 112572062: 112572062
176MYBPC3NM_000256.3(MYBPC3): c.2618C> A (p.Pro873His)single nucleotide variantLikely pathogenic, Pathogenicrs371401403GRCh37Chr 11, 47357547: 47357547
177JPH2NM_020433.4(JPH2): c.1513G> A (p.Gly505Ser)single nucleotide variantPathogenicrs140740776GRCh37Chr 20, 42744802: 42744802
178MYL2NM_000432.3(MYL2): c.141C> A (p.Asn47Lys)single nucleotide variantPathogenicrs199474808GRCh37Chr 12, 111353547: 111353547
179MYL3NM_000258.2(MYL3): c.281G> A (p.Arg94His)single nucleotide variantLikely pathogenic, Pathogenicrs199474703GRCh37Chr 3, 46902192: 46902192
180MYL3NM_000258.2(MYL3): c.170C> G (p.Ala57Gly)single nucleotide variantPathogenicrs139794067GRCh37Chr 3, 46902303: 46902303
181MYPNNM_032578.3(MYPN): c.3335C> T (p.Pro1112Leu)single nucleotide variantLikely pathogenic, Pathogenicrs71534278GRCh37Chr 10, 69959174: 69959174
182MYPNNM_032578.3(MYPN): c.3583G> A (p.Val1195Met)single nucleotide variantPathogenicrs71534280GRCh37Chr 10, 69961675: 69961675
183MYPNNM_032578.3(MYPN): c.59A> G (p.Tyr20Cys)single nucleotide variantLikely pathogenic, Pathogenicrs140148105GRCh37Chr 10, 69881254: 69881254
184TPM1NM_001018005.1(TPM1): c.515T> C (p.Ile172Thr)single nucleotide variantPathogenicrs199476312GRCh37Chr 15, 63353090: 63353090
185TPM1NM_001018005.1(TPM1): c.574G> A (p.Glu192Lys)single nucleotide variantLikely pathogenic, Pathogenicrs199476315GRCh37Chr 15, 63353922: 63353922
186TPM1NM_001018005.1(TPM1): c.644C> T (p.Ser215Leu)single nucleotide variantLikely pathogenic, Pathogenicrs199476316GRCh37Chr 15, 63354418: 63354418
187TPM1NM_001018005.1(TPM1): c.688G> A (p.Asp230Asn)single nucleotide variantPathogenicrs199476317GRCh37Chr 15, 63354462: 63354462
188NEXNNM_144573.3(NEXN): c.1955A> G (p.Tyr652Cys)single nucleotide variantLikely pathogenic, Pathogenicrs137853197GRCh37Chr 1, 78408441: 78408441
189MYBPC3NM_000256.3(MYBPC3): c.1321G> A (p.Glu441Lys)single nucleotide variantLikely pathogenic, Pathogenicrs193922377GRCh37Chr 11, 47364602: 47364602
190MYBPC3NM_000256.3(MYBPC3): c.2308G> A (p.Asp770Asn)single nucleotide variantLikely pathogenic, Pathogenicrs36211723GRCh37Chr 11, 47360071: 47360071
191MYBPC3NM_000256.3(MYBPC3): c.2374T> C (p.Trp792Arg)single nucleotide variantLikely pathogenic, Pathogenicrs187830361GRCh37Chr 11, 47359280: 47359280
192MYBPC3NM_000256.3(MYBPC3): c.932C> A (p.Ser311Ter)single nucleotide variantLikely pathogenic, Pathogenicrs193922386GRCh37Chr 11, 47367916: 47367916
193MYH7NM_000257.3(MYH7): c.3981C> A (p.Asn1327Lys)single nucleotide variantLikely pathogenic, Pathogenicrs141764279GRCh37Chr 14, 23887607: 23887607
194NM_000257.3(MYH7): c.5135G> A (p.Arg1712Gln)single nucleotide variantLikely pathogenic, Pathogenicrs193922390GRCh37Chr 14, 23884860: 23884860
195TTRNM_000371.3(TTR): c.210T> A (p.Ser70Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121918076GRCh37Chr 18, 29175092: 29175092
196MYBPC3NM_000256.3(MYBPC3): c.2827C> T (p.Arg943Ter)single nucleotide variantPathogenicrs387907267GRCh37Chr 11, 47356671: 47356671
197PTPN11NM_002834.3(PTPN11): c.124A> G (p.Thr42Ala)single nucleotide variantPathogenicrs397507501GRCh37Chr 12, 112884189: 112884189
198PTPN11NM_002834.3(PTPN11): c.155C> T (p.Thr52Ile)single nucleotide variantLikely pathogenicrs397507503GRCh37Chr 12, 112888139: 112888139
199PTPN11NM_002834.3(PTPN11): c.172A> C (p.Asn58His)single nucleotide variantPathogenicrs397507505GRCh37Chr 12, 112888156: 112888156
200PTPN11NM_002834.3(PTPN11): c.172A> G (p.Asn58Asp)single nucleotide variantPathogenicrs397507505GRCh37Chr 12, 112888156: 112888156
201PTPN11NM_002834.3(PTPN11): c.174C> A (p.Asn58Lys)single nucleotide variantPathogenicrs397507506GRCh37Chr 12, 112888158: 112888158
202PTPN11NM_002834.3(PTPN11): c.174C> G (p.Asn58Lys)single nucleotide variantLikely pathogenic, Pathogenicrs397507506GRCh37Chr 12, 112888158: 112888158
203PTPN11NM_002834.3(PTPN11): c.178G> A (p.Gly60Ser)single nucleotide variantLikely pathogenic, Pathogenicrs397507507GRCh37Chr 12, 112888162: 112888162
204PTPN11NM_002834.3(PTPN11): c.179G> C (p.Gly60Ala)single nucleotide variantPathogenicrs397507509GRCh37Chr 12, 112888163: 112888163
205PTPN11NM_002834.3(PTPN11): c.181G> A (p.Asp61Asn)single nucleotide variantPathogenicrs397507510GRCh37Chr 12, 112888165: 112888165
206PTPN11NM_002834.3(PTPN11): c.205G> C (p.Glu69Gln)single nucleotide variantPathogenicrs397507511GRCh37Chr 12, 112888189: 112888189
207PTPN11NM_002834.3(PTPN11): c.211T> C (p.Phe71Leu)single nucleotide variantLikely pathogenic, Pathogenicrs397507512GRCh37Chr 12, 112888195: 112888195
208PTPN11NM_002834.3(PTPN11): c.214G> C (p.Ala72Pro)single nucleotide variantLikely pathogenic, Pathogenicrs121918453GRCh37Chr 12, 112888198: 112888198
209PTPN11NM_002834.3(PTPN11): c.228G> T (p.Glu76Asp)single nucleotide variantPathogenicrs397507514GRCh37Chr 12, 112888212: 112888212
210PTPN11NM_002834.3(PTPN11): c.228G> C (p.Glu76Asp)single nucleotide variantPathogenicrs397507514GRCh37Chr 12, 112888212: 112888212
211PTPN11NM_002834.3(PTPN11): c.317A> C (p.Asp106Ala)single nucleotide variantPathogenicrs397507517GRCh37Chr 12, 112888301: 112888301
212PTPN11NM_002834.3(PTPN11): c.328G> A (p.Glu110Lys)single nucleotide variantPathogenicrs397507518GRCh37Chr 12, 112888312: 112888312
213PTPN11NM_002834.3(PTPN11): c.417G> T (p.Glu139Asp)single nucleotide variantPathogenicrs397507520GRCh37Chr 12, 112891083: 112891083
214PTPN11NM_002834.3(PTPN11): c.417G> C (p.Glu139Asp)single nucleotide variantPathogenicrs397507520GRCh37Chr 12, 112891083: 112891083
215PTPN11NM_002834.3(PTPN11): c.767A> G (p.Gln256Arg)single nucleotide variantLikely pathogenic, Pathogenicrs397507523GRCh37Chr 12, 112910758: 112910758
216PTPN11NM_002834.3(PTPN11): c.781C> T (p.Leu261Phe)single nucleotide variantLikely pathogenic, Pathogenicrs397507525GRCh37Chr 12, 112910772: 112910772
217PTPN11NM_002834.3(PTPN11): c.785T> G (p.Leu262Arg)single nucleotide variantPathogenicrs397507526GRCh37Chr 12, 112910776: 112910776
218PTPN11NM_002834.3(PTPN11): c.794G> A (p.Arg265Gln)single nucleotide variantLikely pathogenicrs376607329GRCh37Chr 12, 112910785: 112910785
219PTPN11NM_002834.3(PTPN11): c.802G> T (p.Gly268Cys)single nucleotide variantLikely pathogenic, Pathogenicrs397507527GRCh37Chr 12, 112910793: 112910793
220PTPN11NM_002834.3(PTPN11): c.844A> G (p.Ile282Val)single nucleotide variantPathogenicrs397507529GRCh37Chr 12, 112910835: 112910835
221PTPN11NM_002834.3(PTPN11): c.846C> G (p.Ile282Met)single nucleotide variantLikely pathogenic, Pathogenicrs397507530GRCh37Chr 12, 112910837: 112910837
222PTPN11NM_002834.3(PTPN11): c.853T> C (p.Phe285Leu)single nucleotide variantPathogenicrs397507531GRCh37Chr 12, 112910844: 112910844
223PTPN11NM_002834.3(PTPN11): c.854T> G (p.Phe285Cys)single nucleotide variantPathogenicrs121918463GRCh37Chr 12, 112915455: 112915455
224PTPN11NM_002834.3(PTPN11): c.923A> C (p.Asn308Thr)single nucleotide variantPathogenicrs121918455GRCh37Chr 12, 112915524: 112915524
225PTPN11NM_002834.3(PTPN11): c.1471C> A (p.Pro491Thr)single nucleotide variantPathogenicrs397507539GRCh37Chr 12, 112926851: 112926851
226PTPN11NM_002834.3(PTPN11): c.1471C> T (p.Pro491Ser)single nucleotide variantPathogenicrs397507539GRCh37Chr 12, 112926851: 112926851
227PTPN11NM_002834.3(PTPN11): c.1472C> A (p.Pro491His)single nucleotide variantLikely pathogenic, Pathogenicrs397507540GRCh37Chr 12, 112926852: 112926852
228PTPN11NM_002834.3(PTPN11): c.1472C> T (p.Pro491Leu)single nucleotide variantPathogenicrs397507540GRCh37Chr 12, 112926852: 112926852
229PTPN11NM_002834.3(PTPN11): c.1492C> T (p.Arg498Trp)single nucleotide variantPathogenicrs397507541GRCh37Chr 12, 112926872: 112926872
230PTPN11NM_002834.3(PTPN11): c.1493G> T (p.Arg498Leu)single nucleotide variantPathogenicrs397507542GRCh37Chr 12, 112926873: 112926873
231PTPN11NM_002834.3(PTPN11): c.1502G> A (p.Arg501Lys)single nucleotide variantPathogenicrs397507543GRCh37Chr 12, 112926882: 112926882
232PTPN11NM_002834.3(PTPN11): c.1504T> G (p.Ser502Ala)single nucleotide variantPathogenicrs121918458GRCh37Chr 12, 112926884: 112926884
233PTPN11NM_002834.3(PTPN11): c.1505C> T (p.Ser502Leu)single nucleotide variantPathogenicrs397507544GRCh37Chr 12, 112926885: 112926885
234PTPN11NM_002834.3(PTPN11): c.1507G> C (p.Gly503Arg)single nucleotide variantPathogenicrs397507545GRCh37Chr 12, 112926887: 112926887
235PTPN11NM_002834.3(PTPN11): c.1507G> A (p.Gly503Arg)single nucleotide variantPathogenicrs397507545GRCh37Chr 12, 112926887: 112926887
236PTPN11NM_002834.3(PTPN11): c.1510A> G (p.Met504Val)single nucleotide variantPathogenicrs397507547GRCh37Chr 12, 112926890: 112926890
237PTPN11NM_002834.3(PTPN11): c.1517A> C (p.Gln506Pro)single nucleotide variantPathogenicrs397507548GRCh37Chr 12, 112926897: 112926897
238PTPN11NM_002834.3(PTPN11): c.1528C> G (p.Gln510Glu)single nucleotide variantPathogenicrs397507549GRCh37Chr 12, 112926908: 112926908
239RAF1NM_002880.3(RAF1): c.524A> G (p.His175Arg)single nucleotide variantPathogenicrs397516822GRCh37Chr 3, 12650322: 12650322
240RAF1NM_002880.3(RAF1): c.781C> G (p.Pro261Ala)single nucleotide variantPathogenicrs121434594GRCh37Chr 3, 12645688: 12645688
241RAF1NM_002880.3(RAF1): c.788T> G (p.Val263Gly)single nucleotide variantLikely pathogenic, Pathogenicrs397516830GRCh37Chr 3, 12645681: 12645681
242RAF1NM_002880.3(RAF1): c.1457A> G (p.Asp486Gly)single nucleotide variantLikely pathogenicrs397516815GRCh37Chr 3, 12627259: 12627259
243SOS1NM_005633.3(SOS1): c.1655G> A (p.Arg552Lys)single nucleotide variantPathogenicrs397517154GRCh37Chr 2, 39249914: 39249914
244SOS1NM_005633.3(SOS1): c.2104T> C (p.Tyr702His)single nucleotide variantPathogenicrs727505381GRCh37Chr 2, 39240664: 39240664
245MYBPC3NM_000256.3(MYBPC3): c.1168delC (p.His390Metfs)deletionPathogenicrs397515889GRCh37Chr 11, 47365098: 47365098
246MYBPC3NM_000256.3(MYBPC3): c.1224-2A> Gsingle nucleotide variantPathogenicrs397515891GRCh37Chr 11, 47364815: 47364815
247MYBPC3NM_000256.3(MYBPC3): c.1235_1236delTT (p.Phe412Terfs)deletionPathogenicrs397515894GRCh37Chr 11, 47364687: 47364688
248MYBPC3NM_000256.3(MYBPC3): c.1351+2T> Csingle nucleotide variantPathogenicrs397515897GRCh37Chr 11, 47364570: 47364570
249MYBPC3NM_000256.3(MYBPC3): c.1458-1G> Asingle nucleotide variantPathogenicrs397515903GRCh37Chr 11, 47364296: 47364296
250MYBPC3NM_000256.3(MYBPC3): c.1468G> A (p.Gly490Arg)single nucleotide variantPathogenicrs200625851GRCh37Chr 11, 47364285: 47364285
251MYBPC3NM_000256.3(MYBPC3): c.1483C> G (p.Arg495Gly)single nucleotide variantLikely pathogenic, Pathogenicrs397515905GRCh37Chr 11, 47364270: 47364270
252MYBPC3NM_000256.3(MYBPC3): c.1504C> T (p.Arg502Trp)single nucleotide variantPathogenicrs375882485GRCh37Chr 11, 47364249: 47364249
253MYBPC3NM_000256.3(MYBPC3): c.1505G> A (p.Arg502Gln)single nucleotide variantLikely pathogenic, Pathogenicrs397515907GRCh37Chr 11, 47364248: 47364248
254MYBPC3NM_000256.3(MYBPC3): c.1591G> C (p.Gly531Arg)single nucleotide variantLikely pathogenic, Pathogenicrs397515912GRCh37Chr 11, 47364162: 47364162
255MYBPC3NM_000256.3(MYBPC3): c.1624+4A> Tsingle nucleotide variantLikely pathogenic, Pathogenicrs397515916GRCh37Chr 11, 47364125: 47364125
256MYBPC3NM_000256.3(MYBPC3): c.177_187delAGAGGGCACAC (p.Glu60Alafs)deletionPathogenicrs397515925GRCh37Chr 11, 47372895: 47372905
257MYBPC3NM_000256.3(MYBPC3): c.1800delA (p.Lys600Asnfs)deletionPathogenicrs397515926GRCh37Chr 11, 47362786: 47362786
258MYBPC3NM_000256.3(MYBPC3): c.1814A> G (p.Asp605Gly)single nucleotide variantPathogenicrs372371774GRCh37Chr 11, 47362772: 47362772
259MYBPC3NM_000256.3(MYBPC3): c.1828G> A (p.Asp610Asn)single nucleotide variantLikely pathogenic, Pathogenicrs371564200GRCh37Chr 11, 47362758: 47362758
260MYBPC3NM_000256.3(MYBPC3): c.184A> C (p.Thr62Pro)single nucleotide variantPathogenicrs377225516GRCh37Chr 11, 47372898: 47372898
261MYBPC3NM_000256.3(MYBPC3): c.1895delT (p.Met632Argfs)deletionPathogenicrs397515934GRCh37Chr 11, 47362691: 47362691
262MYBPC3NM_000256.3(MYBPC3): c.1897+1G> Asingle nucleotide variantPathogenicrs397515935GRCh37Chr 11, 47362688: 47362688
263MYBPC3NM_000256.3(MYBPC3): c.1928-2A> Gsingle nucleotide variantPathogenicrs397515937GRCh37Chr 11, 47361343: 47361343
264MYBPC3NM_000256.3(MYBPC3): c.2048G> A (p.Trp683Ter)single nucleotide variantPathogenicrs397515942GRCh37Chr 11, 47361221: 47361221
265MYBPC3NM_000256.3(MYBPC3): c.2096delC (p.Pro699Glnfs)deletionPathogenicrs397515947GRCh37Chr 11, 47360927: 47360927
266MYBPC3NM_000256.3(MYBPC3): c.2182G> T (p.Glu728Ter)single nucleotide variantPathogenicrs397515954GRCh37Chr 11, 47360197: 47360197
267MYBPC3NM_000256.3(MYBPC3): c.2308+1G> Asingle nucleotide variantPathogenicrs112738974GRCh37Chr 11, 47360070: 47360070
268MYBPC3NM_000256.3(MYBPC3): c.2308+1G> Tsingle nucleotide variantPathogenicrs112738974GRCh37Chr 11, 47360070: 47360070
269MYBPC3NM_000256.3(MYBPC3): c.2309-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs111729952GRCh37Chr 11, 47359347: 47359347
270MYBPC3NM_000256.3(MYBPC3): c.2311dupG (p.Val771Glyfs)duplicationPathogenicrs397515960GRCh37Chr 11, 47359343: 47359343
271MYBPC3NM_000256.3(MYBPC3): c.2320G> A (p.Ala774Thr)single nucleotide variantPathogenicrs368104687GRCh37Chr 11, 47359334: 47359334
272MYBPC3NM_000256.3(MYBPC3): c.2373dupG (p.Trp792Valfs)duplicationPathogenicrs397515963GRCh37Chr 11, 47359281: 47359281
273MYBPC3NM_000256.3(MYBPC3): c.2429G> A (p.Arg810His)single nucleotide variantLikely pathogenic, Pathogenicrs375675796GRCh37Chr 11, 47359115: 47359115
274MYBPC3NM_000256.3(MYBPC3): c.2454G> A (p.Trp818Ter)single nucleotide variantPathogenicrs397515965GRCh37Chr 11, 47359090: 47359090
275MYBPC3NM_000256.3(MYBPC3): c.2490dupT (p.His831Serfs)duplicationLikely pathogenic, Pathogenicrs397515966GRCh37Chr 11, 47359054: 47359054
276MYBPC3NM_000256.3(MYBPC3): c.2534_2538delGCGTC (p.Arg845Leufs)deletionPathogenicrs397515973GRCh37Chr 11, 47359006: 47359010
277MYBPC3NM_000256.3(MYBPC3): c.2541C> G (p.Tyr847Ter)single nucleotide variantLikely pathogenic, Pathogenicrs397515974GRCh37Chr 11, 47359003: 47359003
278MYBPC3NM_000256.3(MYBPC3): c.2556_2557delCGinsTCT (p.Gly853Leufs)indelPathogenicrs397515975GRCh37Chr 11, 47358987: 47358988
279MYBPC3NM_000256.3(MYBPC3): c.2558delG (p.Gly853Alafs)deletionPathogenicrs397515977GRCh37Chr 11, 47358986: 47358986
280MYBPC3NM_000256.3(MYBPC3): c.26-2A> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs376395543GRCh37Chr 11, 47373058: 47373058
281MYBPC3NM_000256.3(MYBPC3): c.2610dupC (p.Ser871Glnfs)duplicationPathogenicrs397515979GRCh37Chr 11, 47357555: 47357555
282MYBPC3NM_000256.3(MYBPC3): c.2670G> A (p.Trp890Ter)single nucleotide variantPathogenicrs397515982GRCh37Chr 11, 47357495: 47357495
283MYBPC3NM_000256.3(MYBPC3): c.2833_2834delCG (p.Arg945Glyfs)deletionPathogenicrs397515987GRCh37Chr 11, 47356664: 47356665
284MYBPC3NM_000256.3(MYBPC3): c.2864_2865delCT (p.Pro955Argfs)deletionLikely pathogenic, Pathogenicrs397515990GRCh37Chr 11, 47356633: 47356634
285MYBPC3NM_000256.3(MYBPC3): c.2882C> T (p.Pro961Leu)single nucleotide variantPathogenicrs373056282GRCh37Chr 11, 47356616: 47356616
286MYBPC3NM_000256.3(MYBPC3): c.2905+1G> Asingle nucleotide variantPathogenicrs397515991GRCh37Chr 11, 47356592: 47356592
287MYBPC3NM_000256.3(MYBPC3): c.2905C> T (p.Gln969Ter)single nucleotide variantPathogenicrs397515992GRCh37Chr 11, 47356593: 47356593
288MYBPC3NM_000256.3(MYBPC3): c.3065G> C (p.Arg1022Pro)single nucleotide variantLikely pathogenic, Pathogenicrs397516000GRCh37Chr 11, 47355233: 47355233
289MYBPC3NM_000256.3(MYBPC3): c.3181C> T (p.Gln1061Ter)single nucleotide variantPathogenicrs397516005GRCh37Chr 11, 47355117: 47355117
290MYBPC3NM_000256.3(MYBPC3): c.3190+2T> Gsingle nucleotide variantLikely pathogenic, Pathogenicrs113358486GRCh37Chr 11, 47355106: 47355106
291MYBPC3NM_000256.3(MYBPC3): c.3192dupC (p.Lys1065Glnfs)duplicationPathogenicrs397516007GRCh37Chr 11, 47354883: 47354883
292MYBPC3NM_000256.3(MYBPC3): c.3226_3227insT (p.Asp1076Valfs)insertionPathogenicrs397516008GRCh37Chr 11, 47354848: 47354849
293MYBPC3NM_000256.3(MYBPC3): c.3330+5G> Csingle nucleotide variantPathogenicrs373746463GRCh37Chr 11, 47354740: 47354740
294MYBPC3NM_000256.3(MYBPC3): c.3330+5G> Tsingle nucleotide variantLikely pathogenic, Pathogenicrs373746463GRCh37Chr 11, 47354740: 47354740
295MYBPC3NM_000256.3(MYBPC3): c.3476_3479dupTTAT (p.Pro1161Tyrfs)duplicationPathogenicrs397516019GRCh37Chr 11, 47354376: 47354379
296MYBPC3NM_000256.3(MYBPC3): c.3624delC (p.Lys1209Serfs)deletionPathogenicrs397516030GRCh37Chr 11, 47354120: 47354120
297MYBPC3NM_000256.3(MYBPC3): c.3627+1G> Asingle nucleotide variantPathogenicrs397516031GRCh37Chr 11, 47354116: 47354116
298MYBPC3NM_000256.3(MYBPC3): c.3697C> T (p.Gln1233Ter)single nucleotide variantPathogenicrs397516037GRCh37Chr 11, 47353740: 47353740
299MYBPC3NM_000256.3(MYBPC3): c.3742G> A (p.Gly1248Arg)single nucleotide variantPathogenicrs202147520GRCh37Chr 11, 47353695: 47353695
300MYBPC3NM_000256.3(MYBPC3): c.3797G> A (p.Cys1266Tyr)single nucleotide variantLikely pathogenic, Pathogenicrs397516041GRCh37Chr 11, 47353640: 47353640
301MYBPC3NM_000256.3(MYBPC3): c.3811C> T (p.Arg1271Ter)single nucleotide variantPathogenicrs397516042GRCh37Chr 11, 47353626: 47353626
302MYBPC3NM_000256.3(MYBPC3): c.3815-1G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs397516044GRCh37Chr 11, 47353433: 47353433
303MYBPC3NM_000256.3(MYBPC3): c.459delC (p.Ile154Leufs)deletionPathogenicrs397516052GRCh37Chr 11, 47371611: 47371611
304MYBPC3NM_000256.3(MYBPC3): c.551dupT (p.Lys185Glufs)duplicationPathogenicrs397516059GRCh37Chr 11, 47371428: 47371428
305MYBPC3NM_000256.3(MYBPC3): c.613C> T (p.Gln205Ter)single nucleotide variantPathogenicrs397516061GRCh37Chr 11, 47371366: 47371366
306MYBPC3NM_000256.3(MYBPC3): c.655-1G> Asingle nucleotide variantPathogenicrs397516067GRCh37Chr 11, 47370093: 47370093
307MYBPC3NM_000256.3(MYBPC3): c.655G> C (p.Val219Leu)single nucleotide variantLikely pathogenic, Pathogenicrs397516068GRCh37Chr 11, 47370092: 47370092
308MYBPC3NM_000256.3(MYBPC3): c.710A> C (p.Tyr237Ser)single nucleotide variantPathogenicrs397516070GRCh37Chr 11, 47370037: 47370037
309MYBPC3NM_000256.3(MYBPC3): c.821+1G> Asingle nucleotide variantPathogenicrs397516073GRCh37Chr 11, 47369407: 47369407
310MYBPC3NM_000256.3(MYBPC3): c.772G> A (p.Glu258Lys)single nucleotide variantLikely pathogenic, Pathogenicrs397516074GRCh37Chr 11, 47369975: 47369975
311MYBPC3NM_000256.3(MYBPC3): c.927-2A> Gsingle nucleotide variantPathogenicrs397516082GRCh37Chr 11, 47367923: 47367923
312MYBPC3NM_000256.3(MYBPC3): c.927-9G> Asingle nucleotide variantLikely pathogenic, Pathogenicrs397516083GRCh37Chr 11, 47367930: 47367930
313MYH7NM_000257.3(MYH7): c.1106G> A (p.Arg369Gln)single nucleotide variantPathogenicrs397516089GRCh37Chr 14, 23899016: 23899016
314MYH7NM_000257.3(MYH7): c.1273G> A (p.Gly425Arg)single nucleotide variantLikely pathogenic, Pathogenicrs397516097GRCh37Chr 14, 23898298: 23898298
315MYH7NM_000257.3(MYH7): c.1358G> A (p.Arg453His)single nucleotide variantLikely pathogenic, Pathogenicrs397516101GRCh37Chr 14, 23898213: 23898213
316MYH7NM_000257.3(MYH7): c.1987C> T (p.Arg663Cys)single nucleotide variantLikely pathogenic, Pathogenicrs397516127GRCh37Chr 14, 23896043: 23896043
317MYH7NM_000257.3(MYH7): c.1988G> A (p.Arg663His)single nucleotide variantLikely pathogenic, Pathogenicrs371898076GRCh37Chr 14, 23896042: 23896042
318MYH7NM_000257.3(MYH7): c.2167C> G (p.Arg723Gly)single nucleotide variantLikely pathogenic, Pathogenicrs121913630GRCh37Chr 14, 23895023: 23895023
319MYH7NM_000257.3(MYH7): c.2206A> G (p.Ile736Val)single nucleotide variantPathogenicrs397516138GRCh37Chr 14, 23894984: 23894984
320MYH7NM_000257.3(MYH7): c.2221G> A (p.Gly741Arg)single nucleotide variantLikely pathogenic, Pathogenicrs121913632GRCh37Chr 14, 23894969: 23894969
321MYH7NM_000257.3(MYH7): c.2360G> A (p.Arg787His)single nucleotide variantLikely pathogenic, Pathogenicrs376754645GRCh37Chr 14, 23894554: 23894554
322MYH7NM_000257.3(MYH7): c.2389G> A (p.Ala797Thr)single nucleotide variantLikely pathogenic, Pathogenicrs3218716GRCh37Chr 14, 23894525: 23894525
323MYH7NM_000257.3(MYH7): c.2546T> C (p.Met849Thr)single nucleotide variantLikely pathogenic, Pathogenicrs397516156GRCh37Chr 14, 23894111: 23894111
324MYH7NM_000257.3(MYH7): c.2555T> C (p.Met852Thr)single nucleotide variantLikely pathogenic, Pathogenicrs397516157GRCh37Chr 14, 23894102: 23894102
325MYH7NM_000257.3(MYH7): c.2681A> G (p.Glu894Gly)single nucleotide variantLikely pathogenic, Pathogenicrs397516161GRCh37Chr 14, 23893357: 23893357
326MYH7NM_000257.3(MYH7): c.2779G> A (p.Glu927Lys)single nucleotide variantLikely pathogenic, Pathogenicrs397516170GRCh37Chr 14, 23893259: 23893259
327MYH7NM_000257.3(MYH7): c.2788G> A (p.Glu930Lys)single nucleotide variantPathogenicrs397516171GRCh37Chr 14, 23893250: 23893250
328MYH7NM_000257.3(MYH7): c.2791_2793delGAG (p.Glu931del)deletionLikely pathogenic, Pathogenicrs397516172GRCh37Chr 14, 23893245: 23893247
329MYH7NM_000257.3(MYH7): c.3134G> T (p.Arg1045Leu)single nucleotide variantLikely pathogenic, Pathogenicrs397516178GRCh37Chr 14, 23891500: 23891500
330MYH7NM_000257.3(MYH7): c.3286G> T (p.Asp1096Tyr)single nucleotide variantPathogenicrs45478699GRCh37Chr 14, 23890217: 23890217
331MYH7NM_000257.3(MYH7): c.3578G> A (p.Arg1193His)single nucleotide variantLikely pathogenic, Pathogenicrs397516187GRCh37Chr 14, 23889202: 23889202
332MYH7NM_000257.3(MYH7): c.4135G> A (p.Ala1379Thr)single nucleotide variantLikely pathogenic, Pathogenicrs397516202GRCh37Chr 14, 23887453: 23887453
333MYH7NM_000257.3(MYH7): c.4258C> T (p.Arg1420Trp)single nucleotide variantPathogenicrs145213771GRCh37Chr 14, 23886807: 23886807
334MYH7NM_000257.3(MYH7): c.428G> A (p.Arg143Gln)single nucleotide variantLikely pathogenic, Pathogenicrs397516209GRCh37Chr 14, 23901922: 23901922
335NM_000257.3(MYH7): c.4377G> T (p.Lys1459Asn)single nucleotide variantLikely pathogenic, Pathogenicrs201307101GRCh37Chr 14, 23886504: 23886504
336MYH7NM_000257.3(MYH7): c.5401G> A (p.Glu1801Lys)single nucleotide variantLikely pathogenic, Pathogenicrs397516248GRCh37Chr 14, 23884362: 23884362
337MYH7NM_000257.3(MYH7): c.5740G> A (p.Glu1914Lys)single nucleotide variantPathogenicrs397516254GRCh37Chr 14, 23883018: 23883018
338MYH7NM_000257.3(MYH7): c.602T> C (p.Ile201Thr)single nucleotide variantLikely pathogenic, Pathogenicrs397516258GRCh37Chr 14, 23901007: 23901007
339MYH7NM_000257.3(MYH7): c.788T> C (p.Ile263Thr)single nucleotide variantLikely pathogenic, Pathogenicrs397516269GRCh37Chr 14, 23900635: 23900635
340MYH7NM_000257.3(MYH7): c.976G> C (p.Ala326Pro)single nucleotide variantPathogenicrs372731424GRCh37Chr 14, 23899792: 23899792
341MYL3NM_000258.2(MYL3): c.170C> A (p.Ala57Asp)single nucleotide variantPathogenicrs139794067GRCh37Chr 3, 46902303: 46902303
342MYL3NM_000258.2(MYL3): c.460C> T (p.Arg154Cys)single nucleotide variantPathogenicrs143852164GRCh37Chr 3, 46900986: 46900986
343TNNI3NM_000363.4(TNNI3): c.544G> A (p.Glu182Lys)single nucleotide variantPathogenicrs397516355GRCh37Chr 19, 55665403: 55665403
344TNNI3NM_000363.4(TNNI3): c.557G> A (p.Arg186Gln)single nucleotide variantPathogenicrs397516357GRCh37Chr 19, 55663278: 55663278
345MYL2NM_000432.3(MYL2): c.401A> C (p.Glu134Ala)single nucleotide variantLikely pathogenic, Pathogenicrs143139258GRCh37Chr 12, 111350901: 111350901
346MYL2NM_000432.3(MYL2): c.485G> A (p.Gly162Glu)single nucleotide variantLikely pathogenic, Pathogenicrs397516406GRCh37Chr 12, 111348897: 111348897
347MYL2NM_000432.3(MYL2): c.488A> C (p.Glu163Ala)single nucleotide variantLikely pathogenic, Pathogenicrs397516407GRCh37Chr 12, 111348894: 111348894
348TNNT2NM_001001430.2(TNNT2): c.257A> C (p.Asp86Ala)single nucleotide variantLikely pathogenic, Pathogenicrs397516455GRCh37Chr 1, 201334745: 201334745
349TNNT2NM_001001430.2(TNNT2): c.274C> T (p.Arg92Trp)single nucleotide variantLikely pathogenic, Pathogenicrs397516456GRCh37Chr 1, 201334426: 201334426
350TNNT2NM_001001430.2(TNNT2): c.281G> A (p.Arg94His)single nucleotide variantLikely pathogenic, Pathogenicrs397516457GRCh37Chr 1, 201334419: 201334419
351TNNT2NM_001001430.2(TNNT2): c.281G> T (p.Arg94Leu)single nucleotide variantLikely pathogenic, Pathogenicrs397516457GRCh37Chr 1, 201334419: 201334419
352TNNT2NM_001001430.2(TNNT2): c.388C> T (p.Arg130Cys)single nucleotide variantLikely pathogenic, Pathogenicrs397516463GRCh37Chr 1, 201333497: 201333497
353TNNT2NM_001001430.2(TNNT2): c.487_489delGAG (p.Glu163del)deletionLikely pathogenic, Pathogenicrs397516470GRCh37Chr 1, 201332505: 201332507
354TNNT2NM_001001430.2(TNNT2): c.518G> A (p.Arg173Gln)single nucleotide variantLikely pathogenic, Pathogenicrs397516471GRCh37Chr 1, 201332476: 201332476
355TNNT2NM_001001430.2(TNNT2): c.629_631delAGA (p.Lys210del)deletionPathogenicrs45578238GRCh37Chr 1, 201331099: 201331101
356TNNT2NM_000364.3(TNNT2): c.753G> T (p.Glu251Asp)single nucleotide variantPathogenicrs45466197GRCh37Chr 1, 201330455: 201330455
357TNNT2NM_001001430.2(TNNT2): c.833G> A (p.Arg278His)single nucleotide variantPathogenicrs397516484GRCh37Chr 1, 201328372: 201328372
358TNNT2NM_000364.3(TNNT2): c.877C> T (p.Arg293Cys)single nucleotide variantLikely pathogenic, Pathogenicrs367785431GRCh37Chr 1, 201328349: 201328349
359TNNT2NM_000364.3(TNNT2): c.878G> A (p.Arg293His)single nucleotide variantLikely pathogenic, Pathogenicrs141121678GRCh37Chr 1, 201328348: 201328348
360RBM20NM_001134363.2(RBM20): c.1906C> T (p.Arg636Cys)single nucleotide variantPathogenicrs267607002GRCh37Chr 10, 112572061: 112572061
361DSG2NM_001943.3(DSG2): c.1773_1774delTG (p.Cys591Terfs)deletionLikely pathogenic, Pathogenicrs397516703GRCh37Chr 18, 29118835: 29118836
362DSG2NM_001943.3(DSG2): c.523+2T> Csingle nucleotide variantLikely pathogenic, Pathogenicrs397516709GRCh37Chr 18, 29101208: 29101208
363NM_002667.3(PLN): c.40_42delAGA (p.Arg14del)deletionPathogenicrs397516784GRCh37Chr 6, 118880124: 118880126
364PTPN11NM_002834.3(PTPN11): c.1226G> C (p.Gly409Ala)single nucleotide variantPathogenicrs201247699GRCh37Chr 12, 112924280: 112924280
365PTPN11NM_002834.3(PTPN11): c.209A> G (p.Lys70Arg)single nucleotide variantLikely pathogenicrs397516801GRCh37Chr 12, 112888193: 112888193
366PTPN11NM_002834.3(PTPN11): c.217_218delACinsCT (p.Thr73Leu)indelPathogenicrs397516802GRCh37Chr 12, 112888201: 112888202
367PTPN11NM_002834.3(PTPN11): c.235C> A (p.Gln79Lys)single nucleotide variantLikely pathogenicrs397516803GRCh37Chr 12, 112888219: 112888219
368PTPN11NM_002834.3(PTPN11): c.774G> T (p.Glu258Asp)single nucleotide variantLikely pathogenic, Pathogenicrs397516809GRCh37Chr 12, 112910765: 112910765
369PTPN11NM_002834.3(PTPN11): c.802G> A (p.Gly268Ser)single nucleotide variantLikely pathogenic, Pathogenicrs397507527GRCh37Chr 12, 112910793: 112910793
370PTPN11NM_002834.3(PTPN11): c.855T> G (p.Phe285Leu)single nucleotide variantPathogenicrs397516810GRCh37Chr 12, 112915456: 112915456
371RAF1NM_002880.3(RAF1): c.766A> G (p.Arg256Gly)single nucleotide variantLikely pathogenicrs397516825GRCh37Chr 3, 12645703: 12645703
372RAF1NM_002880.3(RAF1): c.768G> C (p.Arg256Ser)single nucleotide variantLikely pathogenicrs397516826GRCh37Chr 3, 12645701: 12645701
373RAF1NM_002880.3(RAF1): c.786T> A (p.Asn262Lys)single nucleotide variantPathogenicrs397516829GRCh37Chr 3, 12645683: 12645683
374BRAFNM_004333.4(BRAF): c.1409C> G (p.Thr470Arg)single nucleotide variantLikely pathogenicrs397516891GRCh37Chr 7, 140481399: 140481399
375BRAFNM_004333.4(BRAF): c.1802A> C (p.Lys601Thr)single nucleotide variantPathogenicrs397507484GRCh37Chr 7, 140453133: 140453133
376BRAFNM_004333.4(BRAF): c.722C> A (p.Thr241Lys)single nucleotide variantPathogenicrs387906660GRCh37Chr 7, 140501350: 140501350
377BRAFNM_004333.4(BRAF): c.793G> C (p.Gly265Arg)single nucleotide variantLikely pathogenicrs397516905GRCh37Chr 7, 140501279: 140501279
378KRASNM_033360.3(KRAS): c.182A> G (p.Gln61Arg)single nucleotide variantPathogenicrs121913240GRCh37Chr 12, 25380276: 25380276
379KRASNM_004985.4(KRAS): c.454G> T (p.Val152Phe)single nucleotide variantLikely pathogenicrs397517041GRCh37Chr 12, 25362842: 25362842
380SOS1NM_005633.3(SOS1): c.1132A> G (p.Thr378Ala)single nucleotide variantLikely pathogenicrs397517146GRCh37Chr 2, 39251221: 39251221
381SOS1NM_005633.3(SOS1): c.1310T> C (p.Ile437Thr)single nucleotide variantPathogenicrs397517150GRCh37Chr 2, 39250259: 39250259
382SOS1NM_005633.3(SOS1): c.1412G> C (p.Cys471Ser)single nucleotide variantLikely pathogenicrs397517151GRCh37Chr 2, 39250157: 39250157
383SOS1NM_005633.3(SOS1): c.3022T> C (p.Tyr1008His)single nucleotide variantLikely pathogenicrs397517163GRCh37Chr 2, 39224122: 39224122
384SOS1NM_005633.3(SOS1): c.335C> G (p.Pro112Arg)single nucleotide variantLikely pathogenicrs397517166GRCh37Chr 2, 39285824: 39285824
385SOS1NM_005633.3(SOS1): c.512T> C (p.Val171Ala)single nucleotide variantLikely pathogenicrs397517174GRCh37Chr 2, 39281963: 39281963
386SOS1NM_005633.3(SOS1): c.925G> T (p.Asp309Tyr)single nucleotide variantPathogenicrs397517180GRCh37Chr 2, 39262581: 39262581
387DSC2NM_024422.4(DSC2): c.846C> G (p.Tyr282Ter)single nucleotide variantLikely pathogenic, Pathogenicrs397517406GRCh37Chr 18, 28666635: 28666635
388SCN5ANM_000335.4(SCN5A): c.2314G> A (p.Asp772Asn)single nucleotide variantPathogenicrs199473157GRCh37Chr 3, 38629013: 38629013
389RIT1RIT1, GLU81GLYsingle nucleotide variantPathogenic
390RIT1RIT1, PHE82LEUsingle nucleotide variantPathogenic
391RIT1NM_006912.5(RIT1): c.284G> C (p.Gly95Ala)single nucleotide variantPathogenicrs672601335GRCh37Chr 1, 155874247: 155874247
392MYBPC3NM_000256.3(MYBPC3): c.3791G> T (p.Cys1264Phe)single nucleotide variantLikely pathogenic, Pathogenicrs397514751GRCh37Chr 11, 47353646: 47353646
393MYBPC3NM_000256.3(MYBPC3): c.2618C> T (p.Pro873Leu)single nucleotide variantLikely pathogenic, Pathogenicrs371401403GRCh37Chr 11, 47357547: 47357547
394GPD1LNM_015141.3(GPD1L): c.839C> T (p.Ala280Val)single nucleotide variantPathogenicrs72552291GRCh37Chr 3, 32200588: 32200588
395GPD1LNM_015141.3(GPD1L): c.370A> G (p.Ile124Val)single nucleotide variantLikely pathogenic, Pathogenicrs72552293GRCh37Chr 3, 32181723: 32181723
396GPD1LNM_015141.3(GPD1L): c.817C> T (p.Arg273Cys)single nucleotide variantLikely pathogenic, Pathogenicrs72552294GRCh37Chr 3, 32200566: 32200566
397MYBPC3NM_000256.3(MYBPC3): c.3330+5G> Asingle nucleotide variantPathogenicrs373746463GRCh37Chr 11, 47354740: 47354740
398MYBPC3NM_000256.3(MYBPC3)duplicationLikely pathogenic, Pathogenicrs193922384GRCh38Chr 11, 47332127: 47332144
399MYBPC3NM_000256.3(MYBPC3): c.3373G> A (p.Val1125Met)single nucleotide variantPathogenicrs121909378GRCh37Chr 11, 47354482: 47354482
400MYBPC3NM_000256.3(MYBPC3): c.1624G> C (p.Glu542Gln)single nucleotide variantLikely pathogenic, Pathogenicrs121909374GRCh37Chr 11, 47364129: 47364129
401MYBPC3NM_000256.3(MYBPC3): c.3286G> T (p.Glu1096Ter)single nucleotide variantLikely pathogenic, Pathogenicrs121909377GRCh37Chr 11, 47354789: 47354789
402MYBPC3NM_000256.3(MYBPC3): c.2459G> A (p.Arg820Gln)single nucleotide variantLikely pathogenic, Pathogenicrs2856655GRCh37Chr 11, 47359085: 47359085
403MYBPC3NM_000256.3(MYBPC3): c.906-1G> Csingle nucleotide variantPathogenicrs587776700GRCh38Chr 11, 47347030: 47347030
404MYBPC3NM_000256.3(MYBPC3): c.3330+2T> Gsingle nucleotide variantPathogenicrs387906397GRCh37Chr 11, 47354743: 47354743
405CSRP3NM_003476.4(CSRP3): c.206A> G (p.Lys69Arg)single nucleotide variantPathogenicrs137852764GRCh37Chr 11, 19209758: 19209758
406CSRP3NM_003476.4(CSRP3): c.136A> C (p.Ser46Arg)single nucleotide variantLikely pathogenic, Pathogenicrs137852765GRCh37Chr 11, 19209828: 19209828
407MYBPC3NM_000256.3(MYBPC3): c.1641_1642delGT (p.Tyr548Profs)deletionPathogenicrs398123279GRCh37Chr 11, 47363690: 47363691

Cosmic variations for Noonan Syndrome 1:

7
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1584NRASskin,lower leg,benign melanocytic nevus,congenital1

Expression for genes affiliated with Noonan Syndrome 1

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Search GEO for disease gene expression data for Noonan Syndrome 1.

Pathways for genes affiliated with Noonan Syndrome 1

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Pathways related to Noonan Syndrome 1 according to GeneCards Suite gene sharing:

(show top 50)    (show all 105)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2BRAF, KRAS, NRAS, RAF1
2
Show member pathways
10.2BRAF, KRAS, NRAS, RAF1
310.2BRAF, KRAS, NRAS, RAF1
410.2BRAF, KRAS, NRAS, RAF1
5
Show member pathways
10.2PTPN11, RAF1, SOS1, SOS2
610.2PTPN11, RAF1, SOS1, SOS2
710.2PTPN11, RAF1, SOS1, SOS2
8
Show member pathways
10.2BRAF, RAF1, SOS1, SOS2
9
B Cell Receptor Signaling Pathway (WikiPathways)
Show member pathways
10.1BRAF, RAF1, SOS1, SOS2
1010.1BRAF, KRAS, RAF1, SOS1, SOS2
1110.1BRAF, KRAS, RAF1, SOS1, SOS2
1210.1KRAS, NRAS, RAF1, SOS1, SOS2
13
Show member pathways
10.1KRAS, NRAS, RAF1, SOS1, SOS2
14
Show member pathways
10.1KRAS, NRAS, RAF1, SOS1, SOS2
15
Show member pathways
10.1BRAF, NRAS, RAF1, SOS1, SOS2
1610.1BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
17
Show member pathways
10.1BRAF, KRAS, PTPN11, RAF1, SOS1, SOS2
1810.1KRAS, NRAS, PTPN11, RAF1, SOS1, SOS2
19
Show member pathways
10.1KRAS, NRAS, PTPN11, RAF1, SOS1, SOS2
20
Show member pathways
10.1KRAS, NRAS, PTPN11, RAF1, SOS1, SOS2
21
B cell receptor signaling pathway (KEGG)
Show member pathways
10.1KRAS, NRAS, PTPN11, RAF1, SOS1, SOS2
22
Show member pathways
10.1KRAS, NRAS, PTPN11, RAF1, SOS1, SOS2
23
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
24
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
25
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
26
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
2710.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
28
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
2910.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
3010.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
31
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
32
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
33
Show member pathways
10.1BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
34
Show member pathways
10.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
3510.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
36
Show member pathways
10.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
37
Show member pathways
10.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
38
Show member pathways
10.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
39
Show member pathways
10.0BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
40
Show member pathways
10.0MYH7, MYL2, MYL3, RAF1, SOS1, SOS2
4110.0KRAS, NRAS, RAF1, SOS1, SOS2, TNNC1
42
Show member pathways
9.9MYL2, MYL3, TNNC1, TNNI3, TNNT2, TPM1
43
Show member pathways
9.9BRAF, KRAS, NRAS, RAF1, SOS1, SOS2
44
Show member pathways
9.9BRAF, KRAS, MYL2, MYL3, NRAS, RAF1
459.9KRAS, NRAS, RAF1, SOS1, SOS2, TNNC1
469.8MYH7, MYL2, MYL3, TNNC1, TNNI3, TNNT2
47
Show member pathways
9.8BRAF, KRAS, MYL2, NRAS, RAF1, SOS1
48
Show member pathways
9.8MYH7, MYL2, MYL3, RAF1, TNNC1, TNNI3
49
Show member pathways
9.7DSG2, MYH7, MYL2, MYL3, TNNC1, TNNI3
50
Show member pathways
9.6BRAF, KRAS, MYH7, MYL2, MYL3, NRAS

GO Terms for genes affiliated with Noonan Syndrome 1

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Cellular components related to Noonan Syndrome 1 according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1muscle myosin complexGO:000585910.9MYH7, MYL3
2troponin complexGO:000586110.8TNNC1, TNNI3, TNNT2
3myosin complexGO:001645910.8MYH7, MYL2, MYL3
4contractile fiberGO:004329210.7TNNC1, TNNI3
5myofibrilGO:003001610.7MYH7, MYL2, TNNI3, TNNT2
6sarcomereGO:003001710.5MYH7, MYL2, MYL3, TNNI3, TNNT2, TPM1
7cytosolGO:00058299.4BRAF, GPD1L, KRAS, MYL2, MYL3, PTPN11

Biological processes related to Noonan Syndrome 1 according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1transition between fast and slow fiberGO:001488311.0MYH7, TNNC1
2positive regulation of small GTPase mediated signal transductionGO:005105711.0SOS1, SOS2
3regulation of pro-B cell differentiationGO:200097311.0SOS1, SOS2
4lymphocyte homeostasisGO:000226011.0SOS1, SOS2
5regulation of muscle filament sliding speedGO:003297210.9TNNC1, TNNT2
6regulation of striated muscle contractionGO:000694210.9MYL2, MYL3
7regulation of T cell proliferationGO:004212910.9SOS1, SOS2
8negative regulation of ATPase activityGO:003278010.9TNNI3, TNNT2
9regulation of T cell differentiation in thymusGO:003308110.9SOS1, SOS2
10heart contractionGO:006004710.9MYL2, TNNI3
11regulation of the force of heart contractionGO:000202610.8MYH7, MYL2, MYL3
12regulation of Rho protein signal transductionGO:003502310.7RAF1, SOS1, SOS2
13regulation of muscle contractionGO:000693710.7TNNC1, TNNI3, TNNT2, TPM1
14leukocyte migrationGO:005090010.7KRAS, NRAS, PTPN11, SOS1
15positive regulation of ATPase activityGO:003278110.7MYL3, TNNT2, TPM1
16MAPK cascadeGO:000016510.5BRAF, KRAS, NRAS, RAF1, SOS1
17activation of MAPKK activityGO:000018610.5BRAF, KRAS, NRAS, RAF1, SOS1
18insulin receptor signaling pathwayGO:000828610.5BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
19fibroblast growth factor receptor signaling pathwayGO:000854310.5BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
20Ras protein signal transductionGO:000726510.5BRAF, KRAS, NRAS, RAF1, RIT1, SOS1
21Fc-epsilon receptor signaling pathwayGO:003809510.5BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
22ventricular cardiac muscle tissue morphogenesisGO:005501010.4MYH7, MYL2, MYL3, TNNC1, TNNI3, TNNT2
23epidermal growth factor receptor signaling pathwayGO:000717310.4BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
24vascular endothelial growth factor receptor signaling pathwayGO:004801010.3BRAF, KRAS, NRAS, RAF1, SOS1
25heart developmentGO:000750710.3MYL2, PTPN11, RAF1, RBM20, TNNI3, TNNT2
26neurotrophin TRK receptor signaling pathwayGO:004801110.3BRAF, KRAS, NRAS, PTPN11, RAF1, RIT1
27innate immune responseGO:004508710.3BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
28axon guidanceGO:000741110.2BRAF, KRAS, NRAS, PTPN11, RAF1, SOS1
29blood coagulationGO:000759610.1KRAS, NRAS, PTPN11, RAF1, SOS1
30small GTPase mediated signal transductionGO:00072649.9BRAF, KRAS, NRAS, RAF1, RIT1, SOS1
31cardiac muscle contractionGO:00600489.8MYH7, MYL2, MYL3, TNNC1, TNNI3, TNNT2
32muscle filament slidingGO:00300499.5MYH7, MYL2, MYL3, TNNC1, TNNI3, TNNT2

Molecular functions related to Noonan Syndrome 1 according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1troponin T bindingGO:003101410.9TNNC1, TNNI3
2Ras guanyl-nucleotide exchange factor activityGO:000508810.8SOS1, SOS2
3mitogen-activated protein kinase kinase bindingGO:003143410.8BRAF, RAF1
4troponin C bindingGO:003017210.8TNNI3, TNNT2
5troponin I bindingGO:003101310.7TNNC1, TNNT2
6protein heterodimerization activityGO:004698210.0BRAF, MYH7, RAF1, SOS1, SOS2, TTR
7structural constituent of muscleGO:00083079.9MYL2, MYL3, TPM1

Sources for Noonan Syndrome 1

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet