MCID: NRM002
MIFTS: 48

Normal Pressure Hydrocephalus malady

Categories: Neuronal diseases, Rare diseases

Aliases & Classifications for Normal Pressure Hydrocephalus

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Sources:
10Disease Ontology, 46NINDS, 12DISEASES, 51Orphanet, 47Novoseek, 36MeSH, 65UMLS, 27ICD10, 59SNOMED-CT, 28ICD10 via Orphanet, 66UMLS via Orphanet, 61The Human Phenotype Ontology
See all MalaCards sources

Aliases & Descriptions for Normal Pressure Hydrocephalus:

Name: Normal Pressure Hydrocephalus 10 46 12 51
Hydrocephalus, Normal Pressure 36 65
Hydrocephalus - Normal Pressure 46
Hydrocephalus Normal Pressure 47
 
Chronic Adult Hydrocephalus 51
Low Pressure Hydrocephalus 10
Nph 51

Characteristics:

Orphanet epidemiological data:

51
normal pressure hydrocephalus:
Inheritance: Not applicable; Age of onset: Adult


Classifications:



External Ids:

Disease Ontology10 DOID:1572
ICD1027 G91.2
MeSH36 D006850
SNOMED-CT59 30753002, 69663004
Orphanet51 314928
ICD10 via Orphanet28 G91.2
UMLS via Orphanet66 C0020258
UMLS65 C0020258

Summaries for Normal Pressure Hydrocephalus

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NINDS:46 Normal pressure hydrocephalus (NPH) is an abnormal buildup of cerebrospinal fluid (CSF) in the brain's ventricles, or cavities. It occurs if the normal flow of CSF throughout the brain and spinal cord is blocked in some way. This causes the ventricles to enlarge, putting pressure on the brain. Normal pressure hydrocephalus can occur in people of any age, but it is most common in the elderly. It may result from a subarachnoid hemorrhage, head trauma, infection, tumor, or complications of surgery. However, many people develop NPH even when none of these factors are present. In these cases the cause of the disorder is unknown.

MalaCards based summary: Normal Pressure Hydrocephalus, also known as hydrocephalus, normal pressure, is related to headache and cerebritis, and has symptoms including bowel incontinence, normal pressure hydrocephalus and gait disturbance. An important gene associated with Normal Pressure Hydrocephalus is PMPCA (Peptidase, Mitochondrial Processing Alpha Subunit), and among its related pathways are A-beta Pathways: Uptake and Degradation and Sympathetic Nerve Pathway (Neuroeffector Junction). Affiliated tissues include brain, spinal cord and lung, and related mouse phenotypes are muscle and immune system.

Wikipedia:68 Normal pressure hydrocephalus (NPH), also termed symptomatic hydrocephalus, is a type of brain... more...

Related Diseases for Normal Pressure Hydrocephalus

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Graphical network of the top 20 diseases related to Normal Pressure Hydrocephalus:



Diseases related to normal pressure hydrocephalus

Symptoms for Normal Pressure Hydrocephalus

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HPO human phenotypes related to Normal Pressure Hydrocephalus:

(show all 6)
id Description Frequency HPO Source Accession
1 bowel incontinence HP:0002607
2 normal pressure hydrocephalus HP:0002343
3 gait disturbance HP:0001288
4 global developmental delay HP:0001263
5 dementia HP:0000726
6 urinary incontinence HP:0000020

Drugs & Therapeutics for Normal Pressure Hydrocephalus

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Drugs for Normal Pressure Hydrocephalus (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 19)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
CitalopramapprovedPhase 449459729-33-82771
Synonyms:
1,3-Dihydro-1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)-5-isobenzofurancarbonitrile
1,3-dihydro[3,4]benzofuran-5-carbonitrile
1-(3-(Dimethylamino)propyl)-1-(p-fluorophenyl)-5-phthalancarbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-3H-2-benzofuran-5-carbonitrile
59729-33-8
AB00513896
AC-12214
AC1L1EFH
AE-641/00603021
Akarin
BPBio1_000929
BRD-A47598013-004-02-0
BSPBio_000843
Bonitrile
C07572
C20H21FN2O
CHEBI:3723
CHEMBL549
CID2771
CPD000465669
Celapram
Celexa
Celius
Ciazil
Cilift
Cipram
Cipramil
Ciprapine
Citabax
Citadur
Citadur (TN)
Citalec
Citalopram
Citalopram (USP/INN)
Citalopram Hydrobromide
Citalopram [Celexa]
Citalopram [INN:BAN]
Citalopram hydrobromide
Citalopramum
Citalopramum [INN-Latin]
 
Citol
Citopam
Citox
Citrol
Cytalopram
D07704
DB00215
Dalsan
EINECS 261-891-1
Elopram
HMS2090O09
HMS2093A14
Humorup
I01-0382
InChI=1/C20H21FN2O/c1-23(2)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-24-20/h4-9,12H,3,10-11,14H2,1-2H3
L001223
LS-84327
Lopac0_000258
Lu 10-171
Lu-10-171
MolPort-003-666-794
NCGC00015267-07
NCGC00025160-02
Nitalapram
Oropram
Perrigo Citalopram
Pramcit
Prestwick3_000692
Recital
SAM002589960
ST069372
STL058639
Seropram
Talam
Talohexal
Temperax
UNII-0DHU5B8D6V
Vodelax
Zentius
Zetalo
[3H]Citalopram
citalopram
2
SerotoninPhase 4314750-67-95202
Synonyms:
3-(2-Aminoethyl)-1H-indol-5-ol
3-(2-Aminoethyl)indol-5-ol
3-(b-Aminoethyl)-5-hydroxyindole
5-HT
5-HTA
5-Hydroxy-3-(b-aminoethyl)indole
 
5-Hydroxy-tryptamine
5-Hydroxyltryptamine
5-Hydroxytriptamine
5-Hydroxytryptamine
Antemovis
DS substance
Enteramin
Enteramine
3Serotonin AgentsPhase 42668
4Neurotransmitter Uptake InhibitorsPhase 42857
5Serotonin Uptake InhibitorsPhase 41369
6Neurotransmitter AgentsPhase 414795
7Cholinergic AntagonistsPhase 41423
8Muscarinic AntagonistsPhase 4961
9Cholinergic AgentsPhase 43243
10
AcetazolamideapprovedPhase 36759-66-51986
Synonyms:
1424-27-7 (mono-hydrochloride salt)
1yda
1ydb
1ydd
1zsb
2-acetylamino-1,3,4-Thiadiazole-5-sulfonamide
2h4n
3czv
4-Diamox
5-ACETAMIDO-1,3,4-thiadiazole-2-sulfonamide
5-acetylamino-1,3,4-Thiadiazole-2-sulfonamide
5661-25-6
59-66-5
8017-69-4
A 6011
A6011_SIAL
A6011_SIGMA
AB00051906
AC-12779
AC1L1CO5
AI3-52458
AKOS000715163
Acetadiazol
Acetamidothiadiazolesulfonamide
Acetamox
Acetazolam
Acetazolamid
Acetazolamida
Acetazolamida [INN-Spanish]
Acetazolamide
Acetazolamide (AAZ)
Acetazolamide (JP15/USP/INN)
Acetazolamide Apotex Brand
Acetazolamide Chiesi Brand
Acetazolamide Dioptic Brand
Acetazolamide Grin Brand
Acetazolamide ICN Brand
Acetazolamide Jumer Brand
Acetazolamide Llorens Brand
Acetazolamide Medphano Brand
Acetazolamide Novopharm Brand
Acetazolamide Orion Brand
Acetazolamide Sodium
Acetazolamide Sodium, (Sterile)
Acetazolamide Wassermann Brand
Acetazolamide [INN:BAN:JAN]
Acetazolamide, Monosodium Salt
Acetazolamidum
Acetazolamidum [INN-Latin]
Acetazolamine
Acetazoleamide
Acetozalamide
Acétazolamide
Ak Zol
Ak-Zol
AkZol
Apo Acetazolamide
Apo-Acetazolamide
ApoAcetazolamide
Apotex Brand of Acetazolamide
Atenezol
Avva
BAS 01585728
BIDD:GT0643
BPBio1_000007
BSPBio_000005
BSPBio_001788
C06805
C4H6N4O3S2
CAS-59-66-5
CCRIS 5811
CHEBI:27690
CHEMBL20
CID1986
CPD0-1626
CPD000058394
Carbonic Anhydrase Inhibitor 6063
Carbonic Anhydrase Inhibitor No. 6063
Carbonic anhydrase inhibitor 6063
Chiesi Brand of Acetazolamide
Ciba Vision Brand of Acetazolamide
Cidamex
D000086
D00218
DB00819
Dazamide
Defiltran
Dehydratin
Diacarb
Diakarb
Diamox
Diamox (TN)
Diamox Sequels
Didoc
 
Diluran
Dioptic Brand of Acetazolamide
Diuramid
Diuramide
Diureticum-Holzinger
Diureticum-holzinger
Diuriwas
Diutazol
DivK1c_000017
Donmox
Duiramid
EINECS 200-440-5
EU-0100039
Edemox
Eumicton
Fonurit
Glauconox
Glaumox
Glaupax
Glupax
Grin Brand of Acetazolamide
HMS1568A07
HMS1920A05
HMS2091G05
HMS500A19
HSDB 3002
Huma Zolamide
Huma-Zolamide
HumaZolamide
I09-0425
ICN Brand of Acetazolamide
IDI1_000017
Jumer Brand of Acetazolamide
KBio1_000017
KBio2_000358
KBio2_002926
KBio2_005494
KBio3_001288
KBioGR_000558
KBioSS_000358
LS-10227
Llorens Brand of Acetazolamide
Lopac-A-6011
Lopac0_000039
MLS000028435
MLS001148438
Medphano Brand of Acetazolamide
MolPort-001-783-578
Monosodium Salt Acetazolamide
N-[5-(Aminosulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
N-[5-(Aminosulfonyl)-1,3,5-thiadiazol-2-yl]acetamide
NCGC00015074-01
NCGC00015074-02
NCGC00015074-03
NCGC00015074-06
NCGC00015074-11
NCGC00023455-03
NCGC00023455-04
NCGC00023455-05
NCGC00023455-06
NCGC00023455-07
NINDS_000017
NSC 145177
NSC145177
Natrionex
Nephramid
Nephramide
Novopharm Brand of Acetazolamide
Orion Brand of Acetazolamide
Phonurit
Prestwick0_000003
Prestwick1_000003
Prestwick2_000003
Prestwick3_000003
Prestwick_4
SAM002554883
SBB056640
SK-acetazolamide
SMR000058394
SPBio_000004
SPBio_001926
SPECTRUM1500102
Sk-Acetazolamide
Spectrum2_000082
Spectrum3_000284
Spectrum4_000139
Spectrum5_000738
Spectrum_000018
Storz Brand of Acetazolamide Preparation
Storzolamide
UNII-O3FX965V0I
Vetamox
WLN: T5NN DSJ CSZW EMV1
Wassermann Brand of Acetazolamide
Wyeth Brand of Acetazolamide Preparation
acetazolamide
11AnestheticsPhase 2, Phase 37385
12Anti-Infective Agents, LocalPhase 2, Phase 3984
13Pharmaceutical SolutionsPhase 2, Phase 37004
14AnticonvulsantsPhase 32249
15Natriuretic AgentsPhase 31403
16Carbonic Anhydrase InhibitorsPhase 3153
17Contraceptives, OralPhase 33734
18diureticsPhase 31194
19Mitogens1386

Interventional clinical trials:

(show all 39)
idNameStatusNCT IDPhase
1Normal Pressure Hydrocephalus (NPH) RegistryCompletedNCT00233701Phase 4
2ShuntCheck Versus Radionuclide in Evaluating Shunt Function in Symptomatic NPH PatientsCompletedNCT01323764Phase 4
3Efficacy and Safety of Selective Serotonin Reuptake Inhibitor (SSRI) in Overactive Bladder PatientsCompletedNCT00902421Phase 4
4ShuntCheck Accuracy in Detecting Shunt Obstruction Normal Pressure Hydrocephalus (NPH) PatientsWithdrawnNCT00793416Phase 4
5PET Imaging of Brain Amyloid in Normal Pressure HydrocephalusCompletedNCT01053312Phase 3
6A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System.CompletedNCT00196196Phase 3
7Normal Pressure Hydrocephalus Treatment by AcetazolamideRecruitingNCT02163330Phase 3
8Clinical Value of Noninvasive Intracranial Pressure MeasurementRecruitingNCT02130219Phase 2, Phase 3
9Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure HydrocephalusTerminatedNCT01092546Phase 3
10ETV Versus Shunt Surgery in Normal Pressure HydrocephalusTerminatedNCT00946127Phase 3
11Study to Evaluate Efficacy of Shunt Operation for Idiopathic Normal Pressure HydrocephalusCompletedNCT00221091Phase 2
12A Trial of High and Low Pressure Level Settings on a Programmable Ventriculoperitoneal Shunt Valve for Idiopathic Normal Pressure HydrocephalusCompletedNCT01570257
13Predictive Value of Flow MRI in Normal Pressure Hydrocephalus SurgeryCompletedNCT01815775Phase 0
14Computerized Neuropsychology in Idiopathic Normal Pressure Hydrocephalus (INPH)CompletedNCT01265251
15Vascular Risk Factors in INPH-patientsCompletedNCT01850914
16A Study Comparing Shunt Placement Versus Endoscopic Third Ventriculostomy in the Treatment of HydrocephalusCompletedNCT01115270
17Cerebrospinal Fluid Proteome in HydrocephalusCompletedNCT02016352
18Improved Analysis Methods for Infusion TestsCompletedNCT01319136
19Intracranial Pressure Waves Via Lumbar PunctureCompletedNCT01374048
20Comparison of Continuous Noninvasive and Invasive Intracranial Pressure Measurement--Celda Infusion SubprotocolCompletedNCT01976559
21Establishing the Physiology of SyringomyeliaCompletedNCT00001327
22Reference Values of Cerebrospinal Fluid Outflow Resistance and Intracranial Pressure in Healthy ElderlyCompletedNCT01188382
23Flow MRI in Normal Pressure HydrocephalusRecruitingNCT01909960
24Computerised Testing of Cognitive Response to Cerebrospinal Fluid Shunting in Idiopathic Normal Pressure HydrocephalusRecruitingNCT01618500
25Prognostic Value of Transforming Growth Factor-Beta 1 in Normal Pressure HydrocephalusRecruitingNCT00600795
26A Randomized Cross-over Study for Normal Pressure HydrocephalusRecruitingNCT01798641
27Novel Parameters for the Prediction of Ventriculoperitoneal Shunting Efficacy in Patients With iNPHRecruitingNCT02495610
28Transcranial and Rapid Magnetic Stimulation for Gait Apraxia Due to Normal Pressure Hydrocephalus and Cerebral IschemiaRecruitingNCT00494689
29Prognostic Value of Aβ Imaging in NPH Prior to Shunt PlacementRecruitingNCT01834625Phase 0
30Magnetic Resonance Elastography in HydrocephalusRecruitingNCT02230124
31An Evaluation of Non-Invasive ICP Monitoring in Patients Undergoing Invasive ICP Monitoring Via an Intraparenchymal Pressure Monitoring DeviceRecruitingNCT02773888
32European Study on Prediction of Outcome in Patients With Idiopathic Normal Pressure HydrocephalusActive, not recruitingNCT00874198
33Noninvasive Intracranial Pressure and Hydrocephalus PatientsEnrolling by invitationNCT02404740
34Effects of Physical Training in iNPHNot yet recruitingNCT02659111
35Cerebral Blood Circulation in Patients With Posterior Fossa Brain TumorNot yet recruitingNCT01476670
36Factors Predicting Response to Shunting in Normal Pressure HydrocephalusTerminatedNCT00613886
37Conservative Versus Surgical Management of Idiopathic Normal Pressure Hydrocephalus (INPH)TerminatedNCT00727142
38Anterior Pituitary Function in Patients With HydrocephalusTerminatedNCT00149721
39Head Circumference Growth in Children Who Develop Multiple Sclerosis Later in LifeWithdrawnNCT01377805

Search NIH Clinical Center for Normal Pressure Hydrocephalus


Cochrane evidence based reviews: hydrocephalus, normal pressure

Genetic Tests for Normal Pressure Hydrocephalus

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Anatomical Context for Normal Pressure Hydrocephalus

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MalaCards organs/tissues related to Normal Pressure Hydrocephalus:

33
Brain, Spinal cord, Lung, Testes, Breast, Prostate, Heart

Animal Models for Normal Pressure Hydrocephalus or affiliated genes

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MGI Mouse Phenotypes related to Normal Pressure Hydrocephalus:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053697.4APOE, APP, GFAP, HCRT, MAPT, TGFBR2
2MP:00053877.2APOE, APP, GFAP, MAPT, PTGDS, TGFBR2
3MP:00028737.1APP, GFAP, MAPT, NPY, PYY, TGFBR2
4MP:00036316.6APOE, APP, GFAP, HCRT, MAPT, NPY
5MP:00053786.2APOE, APP, GFAP, HCRT, MAPT, NPY
6MP:00053866.0APOE, APP, GFAP, HCRT, MAPT, NPY
7MP:00053765.8APOE, APP, GFAP, HCRT, MAPT, NPY

Publications for Normal Pressure Hydrocephalus

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Articles related to Normal Pressure Hydrocephalus:

(show top 50)    (show all 566)
idTitleAuthorsYear
1
Polymorphic variants of the HSD11B1 gene may be involved in adverse metabolic effects of glucocorticoid replacement therapy in Addison's disease. (27083553)
2016
2
The Supportive Role of Insulin-Like Growth Factor-I in the Differentiation of Murine Mesenchymal Stem Cells into Corneal-Like Cells. (27050039)
2016
3
BAG3 regulates formation of the SNARE complex and insulin secretion. (25766323)
2015
4
Incident ischemic heart disease and recent occupational exposure to particulate matter in an aluminum cohort. (23982120)
2014
5
Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties. (25380486)
2014
6
Role of FGF10 on tumorigenesis by MS-K. (24320134)
2014
7
Characterization of fibroblast growth factor receptor 1 in small-cell lung cancer. (24736083)
2014
8
Three dysregulated microRNAs in serum as novel biomarkers for gastric cancer screening. (25367852)
2014
9
Type-3 metabotropic glutamate receptors regulate chemoresistance in glioma stem cells, and their levels are inversely related to survival in patients with malignant gliomas. (23175182)
2013
10
Tremor associated with Klinefelter syndrome - A case series and review of the literature. (24345964)
2013
11
Renal manifestations of severe Rabson-Mendenhall syndrome: a case report. (23497647)
2013
12
CNS involvement at the onset of primary hemophagocytic lymphohistiocytosis. (22422896)
2012
13
Randomized trial of pterygium surgery with mitomycin C application using conjunctival autograft versus conjunctival-limbal autograft. (22153864)
2012
14
Endophthalmitis is not a "never event". (22858024)
2012
15
Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability. (22241790)
2012
16
Regulation of RKIP function by Helicobacter pylori in gastric cancer. (22662230)
2012
17
Anesthetic experience in a pediatric patient with mastocytosis. (22148097)
2011
18
DD genotype of ace gene I/D polymorphism is associated in a Turkish study population with osteoarthritis. (20845076)
2011
19
APOA1 and APOA4 gene polymorphisms influence the effects of dietary fat on LDL particle size and oxidation in healthy young adults. (20164363)
2010
20
Relation of change in apolipoprotein B/apolipoprotein A-I ratio to coronary plaque regression after Pravastatin treatment in patients with coronary artery disease. (20102908)
2010
21
Hyperuricemia is associated with the development of the composite outcomes of new cardiovascular events and chronic allograft nephropathy. (18791445)
2008
22
Small neutralizing molecules to inhibit actions of the chemokine CXCL12. (18556651)
2008
23
Butyrylcholinesterase, ApoE and Alzheimer's disease in a population from the Canary Islands (Spain). (17923322)
2007
24
Understanding cell death: a challenge for biomedicine]. (16776320)
2005
25
Synthesis and structure-activity relationship of N-alkyl Gly-boro-Pro inhibitors of DPP4, FAP, and DPP7. (16085416)
2005
26
Laryngeal squamous cell carcinoma with ectopic production of granulocyte colony-stimulating factor and parathyroid hormone-related protein. (15990969)
2005
27
Primary pulmonary lymphoma: diagnosis and follow-up of 6 cases and review of an uncommon entity. (15850001)
2005
28
Elongation factors on the ribosome. (15922593)
2005
29
Ellipsomyxa gobii gen. et sp. n. (Myxozoa: Ceratomyxidae) in the common goby Pomatoschistus microps (Teleostei: Gobiidae) from Denmark. (14971595)
2003
30
Serum gelatinase B/MMP-9 in primary progressive multiple sclerosis patients treated with interferon-beta-1a. (14504963)
2003
31
Differential regulation of chemokine production in human peritoneal mesothelial cells: IFN-gamma controls neutrophil migration across the mesothelium in vitro and in vivo. (11441112)
2001
32
Case control study of prognostic markers and disease outcome in inflammatory carcinoma breast: a unique clinical experience. (11843851)
2001
33
The effect of thyroxine on the enzymatic activity of the energy metabolism and antioxidant system in the neutrophilic granulocytes of piglets]. (11059392)
2000
34
Sodium azide enhances neutrophil migration and exocytosis: involvement of nitric oxide, cyclic GMP and calcium. (9718094)
1998
35
Flicker parameters are different for suppression of myopia and hyperopia. (9373666)
1997
36
Cryo-EM visualization of an exposed RGD epitope on adenovirus that escapes antibody neutralization. (9135136)
1997
37
5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats. (9399677)
1997
38
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. (9176498)
1997
39
Development of selective low-density lipoprotein (LDL) apheresis system: immobilized polyanion as LDL-specific adsorption for LDL apheresis system. (8853808)
1996
40
The H1-receptor antagonist chlorpheniramine decreases the ending phase of the mismatch negativity of the human auditory event-related potentials. (8834097)
1996
41
Relationship between time of activation of phospholipase C-linked plasma membrane receptors and reloading of intracellular Ca2+ stores in LAN-1 human neuroblastoma cells. (8027061)
1994
42
Phospholipase D-mediated hydrolysis of phosphatidylcholine: role in cell signalling. (8268464)
1993
43
Synthesis and secretion of a fibrinolytically active tissue-type plasminogen activator variant in Escherichia coli. (1902433)
1991
44
Scimitar syndrome. (2376196)
1990
45
Subacute and chronic myelomonocytic leukemia in children (juvenile CML). Clinical and hematologic observations, and identification of prognostic factors. (6589029)
1984
46
Myxedema presenting as profound hypothermia-coma: a case report. (6589876)
1984
47
Congenital angiodysplasia with skeletal affection. (7368842)
1980
48
Pulmonary blastoma. (158135)
1979
49
The surgical approach to canine intervertebral disc disease. (4795128)
1973
50
Radiological diagnosis of gall bladder disease. (13946048)
1962

Variations for Normal Pressure Hydrocephalus

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Clinvar genetic disease variations for Normal Pressure Hydrocephalus:

5
id Gene Variation Type Significance SNP ID Assembly Location
1PMPCANM_015160.2(PMPCA): c.1129G> Asingle nucleotide variantPathogenicrs753611141GRCh38Chr 9, 136418847: 136418847
2PMPCANM_015160.2(PMPCA): c.1066G> Asingle nucleotide variantPathogenicrs768643552GRCh37Chr 9, 139313082: 139313082

Expression for genes affiliated with Normal Pressure Hydrocephalus

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Search GEO for disease gene expression data for Normal Pressure Hydrocephalus.

Pathways for genes affiliated with Normal Pressure Hydrocephalus

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Pathways related to Normal Pressure Hydrocephalus according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.7APOE, APP
29.4NPY, PYY
39.2APP, TGFBR2
49.2APOE, APP, MAPT
59.2APOE, APP, MAPT

GO Terms for genes affiliated with Normal Pressure Hydrocephalus

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Cellular components related to Normal Pressure Hydrocephalus according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor complexGO:00432359.2APP, TGFBR2
2rough endoplasmic reticulumGO:00057919.1APP, HCRT, PTGDS

Biological processes related to Normal Pressure Hydrocephalus according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1neuron projection regenerationGO:003110210.1APOE, GFAP
2cholesterol metabolic processGO:00082039.9APOE, APP
3neuron projection developmentGO:00311759.5APP, NPY
4response to yeastGO:00018789.5NPY, VIP
5antifungal humoral responseGO:00197329.4NPY, VIP
6feeding behaviorGO:00076319.1HCRT, NPY, PYY
7antibacterial humoral responseGO:00197318.8APP, NPY, VIP

Sources for Normal Pressure Hydrocephalus

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet