MCID: NRW001
MIFTS: 31

Norwegian Scabies malady

Categories: Rare diseases, Infectious diseases

Aliases & Classifications for Norwegian Scabies

About this section

Aliases & Descriptions for Norwegian Scabies:

Name: Norwegian Scabies 11 46 13
Crusted Scabies 11 46 66
 
Seven Year Itch 46

Classifications:



External Ids:

Disease Ontology11 DOID:14374
NCIt43 C34855

Summaries for Norwegian Scabies

About this section
NIH Rare Diseases:46 Crusted scabies (also called norwegian scabies) is a severe form of scabies that most often occurs in people who have a weakened immune system, neurological disease, the elderly, the disabled, or those who are mentally incapacitated. it is characterized by thick crusts of skin that contain large numbers of scabies mites and eggs. the usual features of scabies (itching and a rash) are often absent. crusted scabies  is very contagious and can spread easily both by direct skin-to-skin contacts and through contaminated items such as clothing, bedding, and furniture. people with crusted scabies should receive quick and agressive medical treatment for their infestation to prevent outbreaks of scabies.ivermectin is commonly used to treat this form of scabies.   last updated: 7/5/2014

MalaCards based summary: Norwegian Scabies, also known as crusted scabies, is related to scabies and leukemia. An important gene associated with Norwegian Scabies is FOXP3 (Forkhead Box P3), and among its related pathways is Th2 Differentiation Pathway. Affiliated tissues include skin, t cells and testes.

Disease Ontology:11 A scabies that involves infestation of human itch mite sarcoptes scabiei type hominis in immunocompromised and elderly persons, which is characterized by vesicles and formation of thick crusts over the skin, accompanied by abundant mites but only slight itching.

Related Diseases for Norwegian Scabies

About this section

Graphical network of the top 20 diseases related to Norwegian Scabies:



Diseases related to norwegian scabies

Symptoms for Norwegian Scabies

About this section

Drugs & Therapeutics for Norwegian Scabies

About this section

Drugs for Norwegian Scabies (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
PermethrinPhase 33152645-53-140326
Synonyms:
(+)-CIS-PERMETHRIN
(+)-trans-Permethrin
(+-)-cis-Fmc 33297
(+-)-cis-Permethrin
(+-)-trans-Permethrin
(3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
(3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate
1RS,cis-Permethrin
1RS-trans-Permethrin
3-(2,2-Dichloroethenyl)-2,2-dimethylcyclopropane carboxylic acid, (3-phenoxyphenyl) methyl ester
3-Phenoxybenzyle (1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate
3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
442748_SUPELCO
45614_FLUKA
45614_RIEDEL
45893_FLUKA
45893_RIEDEL
47956_SUPELCO
52341-32-9
52341-33-0
52645-53-1
AC1L23IC
AC1Q3FFG
AI3-29296
Acticin Cream
Ambush
BRN 4153590
C21H20Cl2O3
CHEBI:34911
CHEMBL1525
CID40326
 
DB04930
Elimite Cream
FMC 35171
LS-58636
LS-58640
MLS001332525
MLS001332526
MolPort-003-933-021
NCGC00159390-00
NCGC00159390-02
NCGC00159390-04
NCGC00159390-05
NCGC00159390-06
NCGC00159390-07
NCGC00159390-08
NCGC00159390-09
NRDC 146
NRDC 148
Nix Cream Rinse
PS758_SUPELCO
PerFoam
Permethrin
Permethrin (isomers)
Permethrin (isomers) solution
Permethrine,c&t
SMR000778043
ST50975270
TL8003462
Transpermethrin
Transpermethrin [ISO]
[3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
trans-(+-)-Permethrin
2
IvermectinPhase 35470288-86-76474909, 46936176
Synonyms:
(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-20,20b-dihydroxy-5',6,8,19-tetramethyl-6'-[(1S)-1-methylpropyl]-17-oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacyclooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside
22,23-Dihydroxy-avermectin B
22,23-Dihyroavermectin B1
5-O-Demethyl-22,23-dihydro-avermectin A1a
71827-03-7
AB00513813
AC1MJ4GR
AC1N7O27
BPBio1_000322
BRD-K24652731-001-02-7
BSPBio_000292
CHEMBL341047
CID11957587
CID4330618
CID6321424
CID6419971
CID6427057
EU-0100693
FT-0082656
HMS1568O14
 
HMS2089M09
I 8898
I8898_SIGMA
IVERMECTIN
Ivermectin
Ivermectina
Ivermectine
Ivermectinum
Lopac0_000693
MK-933
MLS001333247
MLS001333248
MLS002153248
MolPort-006-394-715
NCGC00094047-01
NCGC00094047-02
NCGC00094047-03
Prestwick2_000156
Prestwick3_000156
Prestwick_516
S1351_Selleck
SMR000857211

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy Study Between Two Different Dosages of an Antiparasitic in Patients With Crusted ScabiesNot yet recruitingNCT02841215Phase 3

Search NIH Clinical Center for Norwegian Scabies

Genetic Tests for Norwegian Scabies

About this section

Anatomical Context for Norwegian Scabies

About this section

MalaCards organs/tissues related to Norwegian Scabies:

34
Skin, T cells, Testes, Monocytes, Colon, Bone, Brain

Animal Models for Norwegian Scabies or affiliated genes

About this section

Publications for Norwegian Scabies

About this section

Articles related to Norwegian Scabies:

(show top 50)    (show all 124)
idTitleAuthorsYear
1
Norwegian scabies: Rare cause of erythroderma. (25657922)
2015
2
Norwegian scabies. (23431220)
2013
3
Norwegian scabies. (23958988)
2013
4
Neonatal Norwegian scabies: three cooperating causes. (21886727)
2009
5
Human T-cell lymphotrophic virus tropical paraparesis, hyperhidrosis and Norwegian scabies. (19747336)
2009
6
Clinical images: Infestation by Norwegian scabies. (19620272)
2009
7
Atypically distributed cutaneous lesions of Norwegian scabies in an HIV-positive man in South India: a case report. (18341688)
2008
8
Unusual laboratory findings in a case of Norwegian scabies provided a clue to diagnosis. (15872307)
2005
9
Norwegian scabies in Peru: the impact of human T cell lymphotropic virus type I infection. (15964976)
2005
10
Norwegian scabies in the immunocompromised patient. (15547127)
2004
11
Norwegian scabies in an elderly patient who died after treatment with gammaBHC. (12729329)
2003
12
Control of transmission of Norwegian scabies. (12026155)
2002
13
Lesson of the week: Norwegian scabies misdiagnosed as an adverse drug reaction. (10617527)
2000
14
Crusted (Norwegian) scabies in two old-age home residents. (11177168)
2000
15
Crusted (Norwegian) scabies in a patient with dystrophic epidermolysis bullosa. (10583180)
1999
16
Crusted (Norwegian) scabies. A simple office test demystifies the 'great imitator'. (10335327)
1999
17
Crusted (Norwegian) scabies induced by use of topical corticosteroids and treated successfully with ivermectin. (10393619)
1999
18
Norwegian scabies complicated by fatal brain abscess in a renal transplant patient. (8684551)
1996
19
Successful treatment of crusted (Norwegian) scabies with ivermectin in two patients with human immunodeficiency virus infection. (8949458)
1996
20
An outbreak of Norwegian scabies in a surgical ward. (7561605)
1995
21
Ivermectin and crusted (Norwegian) scabies. (8538537)
1995
22
Norwegian scabies in a patient with AIDS: report of a case. (7555105)
1995
23
Crusted (Norwegian) scabies as a pre-diagnostic indicator for HTLV-1 infection. (8236396)
1993
24
Norwegian scabies and herpes simplex in a patient with chronic lymphatic leukemia and hypogammaglobulinemia. (1610697)
1992
25
Sepsis associated with Norwegian scabies in patients with acquired immunodeficiency syndrome. (1526178)
1992
26
Management of an outbreak of Norwegian scabies. (1381877)
1992
27
Norwegian scabies in a patient with AIDS. (1571423)
1992
28
Hospital outbreak of scabies stemming from two AIDS patients with Norwegian scabies. (1971073)
1990
29
Norwegian scabies in an infant with acquired immunodeficiency syndrome. (2480080)
1989
30
Staphylococcus aureus colonization of burrows in erythrodermic Norwegian scabies. A case study of iatrogenic contagion. (2972758)
1988
31
Norwegian scabies. (3632515)
1986
32
Hyperkeratotic (Norwegian) scabies and onychomycosis in an immunosuppressed patient. (3156776)
1985
33
Crusted (Norwegian) scabies. (7325921)
1981
34
Norwegian scabies: a case report and review of the literature. (6215767)
1981
35
Norwegian scabies. A new complication of immunosuppressive therapy. (668415)
1978
36
Norwegian scabies developing during treatment with fluorinated steroid therapy. (74177)
1977
37
Mites in the environment of cases of Norwegian scabies. (807230)
1975
38
Letter: Norwegian scabies and monocytic leukemia. (4519013)
1973
39
Letter: Norwegian scabies during immunosuppressive therapy. (4127999)
1973
40
Norwegian scabies, a Christchurch epidemic. (4664566)
1972
41
Norwegian scabies (a clinical study). (4637284)
1972
42
Norwegian scabies and lymphatic leukaemia. (6025578)
1967
43
Norwegian scabies. (6039551)
1967
44
A case of Norwegian scabies. (4220639)
1965
45
NORWEGIAN SCABIES. (14081565)
1964
46
Norwegian scabies (crusted scabies). (13954071)
1963
47
Norwegian scabies. (13570685)
1958
48
Norwegian scabies. (14935303)
1952
49
Ward epidemic from Norwegian scabies. (14869602)
1951
50
Norwegian Scabies. (19987320)
1930

Variations for Norwegian Scabies

About this section

Expression for genes affiliated with Norwegian Scabies

About this section
Search GEO for disease gene expression data for Norwegian Scabies.

Pathways for genes affiliated with Norwegian Scabies

About this section

Pathways related to Norwegian Scabies according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4CD4, FOXP3

GO Terms for genes affiliated with Norwegian Scabies

About this section

Biological processes related to Norwegian Scabies according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine productionGO:00018169.5CD4, FOXP3
2T cell receptor signaling pathwayGO:00508529.5CD4, FOXP3
3T cell activationGO:00421109.4CD4, FOXP3

Sources for Norwegian Scabies

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet