MCID: NRW001
MIFTS: 38

Norwegian Scabies malady

Rare diseases, Infectious diseases categories

Aliases & Classifications for Norwegian Scabies

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Aliases & Descriptions for Norwegian Scabies:

Name: Norwegian Scabies 10 45 12
Crusted Scabies 10 45 65
Scabies Norwegian 10
 
Seven Year Itch 45
Sarcoptic Itch 10
Scabies 65


Classifications:



External Ids:

Disease Ontology10 DOID:14374
NCIt42 C34855

Summaries for Norwegian Scabies

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NIH Rare Diseases:45 Crusted scabies (also called norwegian scabies) is a severe form of scabies that most often occurs in people who have a weakened immune system, neurological disease, the elderly, the disabled, or those who are mentally incapacitated. it is characterized by thick crusts of skin that contain large numbers of scabies mites and eggs. the usual features of scabies (itching and a rash) are often absent. crusted scabies  is very contagious and can spread easily both by direct skin-to-skin contacts and through contaminated items such as clothing, bedding, and furniture. people with crusted scabies should receive quick and agressive medical treatment for their infestation to prevent outbreaks of scabies.ivermectin is commonly used to treat this form of scabies.   last updated: 7/5/2014

MalaCards based summary: Norwegian Scabies, also known as crusted scabies, is related to scabies and leukemia. An important gene associated with Norwegian Scabies is FOXP3 (Forkhead Box P3), and among its related pathways are Primary immunodeficiency and NF-kappaB Signaling. The drugs lindane and ivermectin have been mentioned in the context of this disorder. Affiliated tissues include skin, t cells and bone.

Disease Ontology:10 A scabies that involves infestation of human itch mite sarcoptes scabiei type hominis in immunocompromised and elderly persons, which is characterized by vesicles and formation of thick crusts over the skin, accompanied by abundant mites but only slight itching.

Related Diseases for Norwegian Scabies

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Diseases related to Norwegian Scabies via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 81)
idRelated DiseaseScoreTop Affiliating Genes
1scabies11.2
2leukemia10.5
3acquired immunodeficiency syndrome10.5
4adult t-cell leukemia10.4
5t-cell leukemia10.4
6down syndrome10.4
7herpes simplex10.3
8psoriasis10.3
9burns10.3
10bullous pemphigoid10.3
11epidermolysis bullosa simplex10.3
12juvenile rheumatoid arthritis10.3
13astrocytoma10.3
14tinea corporis10.3
15rheumatoid arthritis10.2
16systemic lupus erythematosus10.2
17asthma10.2
18bacteremia10.2
19leprosy10.2
20arthritis10.2
21langerhans-cell histiocytosis10.2
22toxic shock syndrome10.2
23dermatitis10.2
24endocarditis10.2
25epidermolysis bullosa10.2
26histiocytosis10.2
27lupus erythematosus10.2
28monocytic leukemia10.2
29paraplegia10.2
30vasculitis10.2
31ipex syndrome10.2
32anthracosis10.1CD4, FOXP3
33eosinophilic gastroenteritis10.1CD4, FOXP3
34malignant granular cell myoblastoma10.1CD4, FOXP3
35cd3epsilon deficiency10.1CD4, NT5C
36irf6-related disorders10.0CD4, FOXP3
37central nervous system chondroma10.0ATP2A2, CD79A
38alcohol abuse10.0CD4, FOXP3
39lymphoepithelioma-like thymic carcinoma9.9CD4, CD79A
40protozoal dysentery9.9CD4, CD79A
41mechanical entropion9.9CD4, CD79A
42choroid disease9.9CD4, CD79A
43cycloplegia9.9CD4, CD79A
44cd40 deficiency9.9CD4, CD79A
45diamond-blackfan anemia 19.9CD4, FOXP3
46depersonalization disorder9.9CD4, CD79A
47selective igm deficiency disease9.9CD4, CD79A
48acute pulmonary heart disease9.9CD4, CD79A
49salpingitis9.9CD4, CD79A
50vaginal glandular tumor9.9CD4, CD79A

Graphical network of the top 20 diseases related to Norwegian Scabies:



Diseases related to norwegian scabies

Symptoms for Norwegian Scabies

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Drugs & Therapeutics for Norwegian Scabies

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Norwegian Scabies

Inferred drug relations via UMLS65/NDF-RT43:

Genetic Tests for Norwegian Scabies

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Anatomical Context for Norwegian Scabies

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MalaCards organs/tissues related to Norwegian Scabies:

33
Skin, T cells, Bone, Monocytes, Testes, Colon, Brain

Animal Models for Norwegian Scabies or affiliated genes

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Publications for Norwegian Scabies

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Articles related to Norwegian Scabies:

(show top 50)    (show all 120)
idTitleAuthorsYear
1
Norwegian Scabies. (26265977)
2015
2
Norwegian scabies. (23958988)
2013
3
Crusted Norwegian scabies, an opportunistic infection, with tocilizumab in rheumatoid arthritis. (21441056)
2011
4
Generalized scaling and redness in a 2-month-old boy. Crusted (Norwegian) scabies (CS). (21182645)
2010
5
Norwegian scabies in a renal transplant patient. (20835323)
2010
6
Norwegian scabies in a malnourished young adult: a case report. (20539068)
2010
7
Norwegian scabies associated with herpes simplex infection in a renal transplant patient. (19300201)
2009
8
Norwegian scabies in immunosuppressed patient misdiagnosed as an adverse drug reaction. (19750822)
2009
9
Atypically distributed cutaneous lesions of Norwegian scabies in an HIV-positive man in South India: a case report. (18341688)
2008
10
Unusual laboratory findings in a case of Norwegian scabies provided a clue to diagnosis. (15872307)
2005
11
Norwegian scabies in the immunocompromised patient. (15547127)
2004
12
Norwegian scabies in an elderly patient who died after treatment with gammaBHC. (12729329)
2003
13
Crusted (Norwegian) scabies. (11932093)
2002
14
Severe and Norwegian scabies are strongly associated with retroviral (HIV-1/HTLV-1) infection in Bahia, Brazil. (12045498)
2002
15
Lesson of the week: Norwegian scabies misdiagnosed as an adverse drug reaction. (10617527)
2000
16
Dermacase. Crusted Norwegian scabies. (10386207)
1999
17
Crusted (Norwegian) scabies in a patient with dystrophic epidermolysis bullosa. (10583180)
1999
18
Crusted (Norwegian) scabies. A simple office test demystifies the 'great imitator'. (10335327)
1999
19
Norwegian scabies complicated by fatal brain abscess in a renal transplant patient. (8684551)
1996
20
An outbreak of Norwegian scabies in a surgical ward. (7561605)
1995
21
Ivermectin and crusted (Norwegian) scabies. (8538537)
1995
22
Ivermectin for crusted (Norwegian) scabies. (7838209)
1995
23
Norwegian scabies in a patient with AIDS: report of a case. (7555105)
1995
24
Crusted (Norwegian) scabies as a pre-diagnostic indicator for HTLV-1 infection. (8236396)
1993
25
Norwegian scabies and herpes simplex in a patient with chronic lymphatic leukemia and hypogammaglobulinemia. (1610697)
1992
26
Sepsis associated with Norwegian scabies in patients with acquired immunodeficiency syndrome. (1526178)
1992
27
Nosocomial outbreak of scabies associated with Norwegian scabies in an AIDS patient. (2083297)
1990
28
Hospital outbreak of scabies stemming from two AIDS patients with Norwegian scabies. (1971073)
1990
29
Staphylococcus aureus colonization of burrows in erythrodermic Norwegian scabies. A case study of iatrogenic contagion. (2972758)
1988
30
Acral hyperkeratosis with erythroderma. Norwegian scabies. (2962539)
1988
31
Crusted (Norwegian) scabies. Occurrence in a child undergoing a bone marrow transplant. (3541794)
1987
32
Crusted (Norwegian) scabies: treatment of nail involvement. (2956293)
1987
33
Crusted (Norwegian) scabies with adult T-cell leukemia. (3874601)
1985
34
Hyperkeratotic (Norwegian) scabies and onychomycosis in an immunosuppressed patient. (3156776)
1985
35
Norwegian scabies following topical corticosteroid therapy. (7327916)
1981
36
Norwegian scabies. A new complication of immunosuppressive therapy. (668415)
1978
37
Norwegian scabies. (880632)
1977
38
Norwegian scabies due to Sarcoptes scabiei var Canis. (413492)
1977
39
Norwegian scabies: occurrence in a patient undergoing immunosuppression. (822784)
1976
40
Norwegian scabies in homozygous twins. (945778)
1976
41
Mites in the environment of cases of Norwegian scabies. (807230)
1975
42
Norwegian scabies following topical steroid therapy. (1197167)
1975
43
Norwegian scabies in acute SLE patient treated with high dose corticosteroid. (4443662)
1974
44
Letter: Norwegian scabies and monocytic leukemia. (4519013)
1973
45
Norwegian scabies, a Christchurch epidemic. (4664566)
1972
46
Norwegian scabies and lymphatic leukaemia. (6025578)
1967
47
A case of Norwegian scabies. (4220639)
1965
48
Norwegian scabies (crusted scabies). (13954071)
1963
49
Norwegian scabies. Report of a case. (13712474)
1961
50
Norwegian scabies. (13353984)
1956

Variations for Norwegian Scabies

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Expression for genes affiliated with Norwegian Scabies

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Search GEO for disease gene expression data for Norwegian Scabies.

Pathways for genes affiliated with Norwegian Scabies

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Pathways related to Norwegian Scabies according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.0CD4, CD79A
28.6CD4, CD79A, FOXP3

GO Terms for genes affiliated with Norwegian Scabies

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Biological processes related to Norwegian Scabies according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor signaling pathwayGO:00508529.4CD4, FOXP3
2T cell activationGO:00421109.4CD4, FOXP3
3cytokine productionGO:00018169.1CD4, FOXP3
4adaptive immune responseGO:00022508.9CD4, CD79A

Sources for Norwegian Scabies

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet