MCID: NSD001
MIFTS: 51

Nose Disease

Categories: Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nose Disease

MalaCards integrated aliases for Nose Disease:

Name: Nose Disease 12 14
Nose Diseases 41 69
Abnormality of the Nose 28
Disorder of the Nose 12
Nasal Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2825
MeSH 41 D009668
SNOMED-CT 64 89488007
ICD10 32 J33.9
UMLS 69 C0028432

Summaries for Nose Disease

MalaCards based summary : Nose Disease, also known as nose diseases, is related to vasomotor rhinitis and allergic rhinitis, and has symptoms including rhinorrhea, dyspnea and apnea. An important gene associated with Nose Disease is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Allograft rejection and Immune response Fc epsilon RI pathway. The drugs Amoxicillin and Cefditoren have been mentioned in the context of this disorder. Affiliated tissues include testes, skin and lung, and related phenotypes are Increased transferrin (TF) endocytosis and hematopoietic system

Wikipedia : 72 The visible part of the human nose is the protruding part of the face that bears the nostrils. The shape... more...

Related Diseases for Nose Disease

Diseases related to Nose Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 182)
# Related Disease Score Top Affiliating Genes
1 vasomotor rhinitis 30.0 RNASE3 TAC1 TLR9
2 allergic rhinitis 28.0 CCL11 CXCL8 HRH1 IL10 IL13 IL4
3 rhinitis 28.0 CCL11 CXCL8 CYSLTR1 HRH1 IL13 IL4
4 fraser syndrome 1 10.6
5 bosma arhinia microphthalmia syndrome 10.6
6 cytokine deficiency 10.6 IL13 IL5
7 loeffler endocarditis 10.5 IL5 RNASE3
8 atopic keratoconjunctivitis 10.5 IL4 IL5 RNASE3
9 intrinsic asthma 10.5 IL4 IL5 RNASE3
10 paragonimiasis 10.5 IL13 IL5 RNASE3
11 nut allergy 10.5 IL13 IL5 TLR9
12 blepharoconjunctivitis 10.5 CCL11 IL4 RNASE3
13 eosinophilic gastroenteritis 10.5 CCL11 IL5 RNASE3
14 chronic eosinophilic pneumonia 10.5 CCL11 IL5 RNASE3
15 angioimmunoblastic lymphadenopathy with dysproteinemia 10.5 IL13 IL5
16 pemphigoid gestationis 10.5 CCL11 IL5
17 chronic interstitial cystitis 10.5 CD79A RNASE3
18 intestinal schistosomiasis 10.5 IL13 IL4 IL5
19 chronic tic disorder 10.5 IL13 IL4 IL5
20 enterobiasis 10.5 IL13 IL4 IL5
21 sezary's disease 10.5 IL4 IL5 TLR9
22 cough variant asthma 10.4 IL4 IL5 RNASE3 TRPV1
23 tropical endomyocardial fibrosis 10.4 IL10 IL4
24 maxillary sinusitis 10.4 CD79A RHNO1 RNASE3
25 somatoform disorder 10.4 IL4 TAC1 TRPV1
26 parasitic ichthyosporea infectious disease 10.4 CD79A IL4 RHNO1
27 lichen disease 10.4 CD79A IL4 TLR9
28 rhinosporidiosis 10.4 CD79A IL4 RHNO1
29 prurigo nodularis 10.4 RNASE3 TAC1
30 primary amebic meningoencephalitis 10.4 CD79A IL4 IL5
31 keratoconjunctivitis sicca 10.4 CD79A IL4 TLR9
32 ocular cicatricial pemphigoid 10.4 CD79A IL4 RNASE3
33 neuroschistosomiasis 10.4 CD79A TAC1
34 encapsulated thymoma 10.4 CD79A MUC5B
35 inflammatory bowel disease 4 10.4 IL13 IL4 IL5 RNASE3
36 latex allergy 10.4 IL13 IL4 IL5 RNASE3
37 urinary schistosomiasis 10.4 IL13 IL4 IL5 RNASE3
38 hyperlucent lung 10.4 IL10 IL4
39 status asthmaticus 10.4 CXCL8 IL5 RNASE3
40 exudative glomerulonephritis 10.4 CD79A CXCL8
41 bagassosis 10.4 CXCL8 IL5
42 wells syndrome 10.4 CXCL8 IL5 RNASE3
43 esophageal disease 10.4 IL13 IL5 TRPV1 TSLP
44 eosinophilic pneumonia 10.4 CCL11 IL13 IL5 RNASE3
45 papillary conjunctivitis 10.4 CCL11 CXCL8 IL4
46 dermatitis herpetiformis 10.4 CCL11 CD79A IL4
47 giant papillary conjunctivitis 10.4 CCL11 CXCL8 IL4
48 angiostrongyliasis 10.4 CCL11 IL13 IL4 IL5
49 respiratory syncytial virus infectious disease 10.4 IL13 IL5
50 eosinophilic meningitis 10.4 CCL11 IL13 IL4 IL5

Graphical network of the top 20 diseases related to Nose Disease:



Diseases related to Nose Disease

Symptoms & Phenotypes for Nose Disease

UMLS symptoms related to Nose Disease:


rhinorrhea, dyspnea, apnea

GenomeRNAi Phenotypes related to Nose Disease according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.4 CD79A CXCL8 CYSLTR1 HRH1 IL10 IL13

MGI Mouse Phenotypes related to Nose Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 IL4 CCL11 IL5 CD79A CHD7 MS4A2
2 homeostasis/metabolism MP:0005376 9.97 TSLP IL4 CD79A IL5 CHD7 MUC5B
3 digestive/alimentary MP:0005381 9.87 TSLP IL4 IL5 CHD7 IL10 TLR9
4 immune system MP:0005387 9.83 IL4 CCL11 IL5 CD79A CHD7 MS4A2
5 respiratory system MP:0005388 9.28 TSLP IL4 CCL11 IL5 CHD7 MUC5B

Drugs & Therapeutics for Nose Disease

Drugs for Nose Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 499)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2 26787-78-0 33613 2171
2
Cefditoren Approved, Investigational Phase 4 104145-95-1, 117467-28-4 9870843 9571074
3
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1 58581-89-8 2267
4
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
5
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 51-45-6, 75614-87-8 774
6
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 83-43-2 6741
7
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-24-8 5755
8
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
9
Xylometazoline Approved, Investigational Phase 4 526-36-3 5709
10
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
11
Dexlansoprazole Approved, Investigational Phase 4 138530-94-6, 103577-45-3 9578005
12
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
13
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678
14
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 130018-77-8
15
Metoprolol Approved, Investigational Phase 4 51384-51-1, 37350-58-6 4171
16
Remifentanil Approved Phase 4 132875-61-7 60815
17
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
18
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
19
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1 158966-92-8 5281040
20
Nitric Oxide Approved Phase 4,Phase 1,Phase 2 10102-43-9 145068
21
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2 137-58-6 3676
22
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 1 53-03-2 5865
23
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
24 Racepinephrine Approved Phase 4,Phase 3,Phase 2 329-65-7
25
Loratadine Approved, Investigational Phase 4,Phase 3,Phase 2 79794-75-5 3957
26
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2 100643-71-8 124087
27
Oxymetazoline Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 1491-59-4 4636
28
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 59-42-7 6041
29
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
30
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 242138-07-4
31
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216974-75-3
32
Menthol Approved Phase 4,Phase 2 2216-51-5 16666
33
Budesonide Approved Phase 4,Phase 2,Phase 3,Phase 1 51333-22-3 5281004 63006
34
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
35
Azithromycin Approved Phase 4,Phase 3,Phase 2 83905-01-5 53477736 447043 55185
36
Doxycycline Approved, Investigational, Vet_approved Phase 4,Phase 2 564-25-0 54671203
37
Cocaine Approved, Illicit Phase 4 50-36-2 446220 5760
38
Dopamine Approved Phase 4,Phase 2 51-61-6, 62-31-7 681
39
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 5311068 56032 68602
40
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
41
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 124-94-7 31307
42
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3 50-28-2 5757
43
Ethinyl Estradiol Approved Phase 4,Phase 3 57-63-6 5991
44
Moxifloxacin Approved, Investigational Phase 4,Phase 3 151096-09-2, 354812-41-2 152946
45
Norgestimate Approved, Investigational Phase 4,Phase 3 35189-28-7 6540478
46
Cefdinir Approved Phase 4 91832-40-5 6915944
47
Levofloxacin Approved, Investigational Phase 4,Phase 3 100986-85-4 149096
48
Ofloxacin Approved Phase 4,Phase 3 82419-36-1 4583
49
Hyaluronic acid Approved, Vet_approved Phase 4 9004-61-9 53477741 24759
50
Acetaminophen Approved Phase 4,Phase 2,Phase 3 103-90-2 1983

Interventional clinical trials:

(show top 50) (show all 1336)

# Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 An Open-label Study to Identify Molecular Markers of Steroid Resistance Unknown status NCT01616160 Phase 4 mometasone furoate
3 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
4 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
5 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
6 Elaboration of Patient-friendly Treatment Strategy With Capsaicin Nasal Spray in Patients With Idiopathic Rhinitis Unknown status NCT02288156 Phase 4 Capsaicin;placebo
7 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
8 AZELASTINE/FLUTICASONE (AZE/FLU) Nasal Spray on Symptom Control, Nasal Mediators and Nasal Hyperresponsiveness in Allergic Rhinitis (AR) Unknown status NCT02238353 Phase 4 azelastine + fluticasone;Placebo
9 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
10 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
11 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
12 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
13 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
14 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
15 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
16 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
17 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
18 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
19 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
20 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
21 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
22 Effect of Ketamine Addition to Lidocaine in Rhinoplasty Completed NCT01827020 Phase 4 Lidocaine 2 %;Ketamine plus Lidocaine;Saline
23 Evaluation Of Cloumella Strut Effect In Tip Rotation Completed NCT00467714 Phase 4
24 Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Completed NCT01862523 Phase 4
25 Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Completed NCT01223820 Phase 4 Capsaicin
26 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
27 The PIO II Study of In-office Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
28 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
29 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy Completed NCT02307825 Phase 4 Azithromycin;Placebo
30 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
31 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
32 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
33 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
34 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
35 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
36 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
37 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
38 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
39 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
40 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
41 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
42 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
43 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
44 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate
45 Hemostatic Matrix in Endoscopic Sinus Surgery Completed NCT00242437 Phase 4
46 CHOOSE : Telithromycin, Acute Bacterial Sinusitis Completed NCT00174694 Phase 4 Telithromycin
47 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life Completed NCT00147914 Phase 4 Cefdinir (drug);amoxicillin/clavulanate
48 MP-AzeFlu Allergen Chamber - Onset of Action Study Completed NCT03004131 Phase 4 Azelastine hydrochloride + fluticasone propionate nasal spray;Placebos;fluticasone propionate nasal spray + loratadine
49 Randomized, Double Blind, Parallel Group, Placebo Controlled, Multi-Center Study of the Efficacy and Safety of Cetirizine HCl Syrup vs. Loratadine Syrup vs. Placebo in Treatment of Children With Seasonal Allergic Rhinitis (SAR) Completed NCT02932774 Phase 4 Cetirizine;Loratadine
50 Efficacy of 2LALERG (Homeopathic Drug) in Allergic Rhinitis Related to Grass Pollen Completed NCT02690935 Phase 4 2LALERG;Placebo

Search NIH Clinical Center for Nose Disease

Cochrane evidence based reviews: nose diseases

Genetic Tests for Nose Disease

Genetic tests related to Nose Disease:

# Genetic test Affiliating Genes
1 Abnormality of the Nose 28

Anatomical Context for Nose Disease

MalaCards organs/tissues related to Nose Disease:

38
Testes, Skin, Lung, Eye, Bone, Pituitary, Colon

Publications for Nose Disease

Articles related to Nose Disease:

# Title Authors Year
1
Blue nose disease in the horse. ( 18124494 )
1949

Variations for Nose Disease

Expression for Nose Disease

Search GEO for disease gene expression data for Nose Disease.

Pathways for Nose Disease

Pathways related to Nose Disease according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.6 CCL11 CXCL8 IL10 IL13 IL4 IL5
2
Show member pathways
12.52 CD79A IL13 IL4 IL5 MS4A2
3
Show member pathways
12.35 IL10 IL13 IL4 IL5 TSLP
4
Show member pathways
12.27 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
5
Show member pathways
12.13 CCL11 CXCL8 IL4 TLR9
6 12.12 CXCL8 IL10 IL13 TAC1
7
Show member pathways
12.12 CXCL8 IL10 IL13 IL4 IL5
8 11.96 CD79A IL10 IL4 IL5 PTGDR2
9 11.93 CCL11 CXCL8 IL10 IL13 IL4
10 11.79 CXCL8 IL13 IL4 IL5
11 11.68 IL10 IL4 IL5 TLR9
12
Show member pathways
11.67 CXCL8 IL4 IL5
13 11.65 CCL11 IL10 IL4 IL5
14 11.52 CXCL8 IL10 IL13 IL4
15 11.46 CXCL8 IL10 TLR9
16 11.34 IL10 IL13 IL4 IL5 PTGDR2 TSLP
17 11.24 IL13 IL4 IL5 TSLP
18 11.22 CCL11 IL10 IL13 IL4 IL5
19 11.18 IL10 IL13 IL4 IL5
20 11.08 CCL11 CXCL8 IL10 IL13 IL4 IL5
21 11.04 IL10 IL13 IL4 IL5
22 10.96 CCL11 CXCL8 IL10 IL13 IL4 IL5
23 10.9 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
24 10.79 IL13 IL4 IL5

GO Terms for Nose Disease

Cellular components related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 external side of plasma membrane GO:0009897 9.46 CD79A IL13 MS4A2 TRPV1
3 extracellular space GO:0005615 9.36 CCL11 CXCL8 IL10 IL13 IL4 IL5

Biological processes related to Nose Disease according to GeneCards Suite gene sharing:

(show all 21)
# Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.88 CD79A CYSLTR1 MS4A2 TRPV1
2 regulation of receptor activity GO:0010469 9.8 CCL11 CXCL8 IL10 IL13 IL4 IL5
3 neuropeptide signaling pathway GO:0007218 9.77 CYSLTR1 PTGDR2 TAC1
4 chemotaxis GO:0006935 9.77 CCL11 CXCL8 CYSLTR1 IL4 PTGDR2
5 B cell differentiation GO:0030183 9.72 CD79A IL10 IL4
6 positive regulation of macrophage activation GO:0043032 9.59 IL10 IL13
7 microglial cell activation GO:0001774 9.58 IL13 TRPV1
8 negative regulation of endothelial cell apoptotic process GO:2000352 9.58 IL10 IL13 IL4
9 positive regulation of interleukin-13 production GO:0032736 9.57 IL4 TSLP
10 eosinophil chemotaxis GO:0048245 9.56 CCL11 HRH1
11 immune response GO:0006955 9.56 CCL11 CXCL8 IL10 IL13 IL4 IL5
12 positive regulation of immunoglobulin production GO:0002639 9.54 IL13 TLR9
13 positive regulation of MHC class II biosynthetic process GO:0045348 9.51 IL10 IL4
14 response to molecule of bacterial origin GO:0002237 9.5 CXCL8 IL10 TLR9
15 type 2 immune response GO:0042092 9.49 IL10 IL4
16 negative regulation of interleukin-8 production GO:0032717 9.48 IL10 TLR9
17 regulation of isotype switching GO:0045191 9.46 IL10 IL4
18 positive regulation of B cell proliferation GO:0030890 9.46 IL13 IL4 IL5 TLR9
19 negative regulation of complement-dependent cytotoxicity GO:1903660 9.43 IL13 IL4
20 inflammatory response GO:0006954 9.32 CCL11 CXCL8 HRH1 IL10 IL13 IL5
21 signal transduction GO:0007165 10.18 CCL11 CXCL8 CYSLTR1 HRH1 IL13 MS4A2

Molecular functions related to Nose Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL11 CXCL8 IL10 IL13 IL4 IL5

Sources for Nose Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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