MCID: NSD001
MIFTS: 49

Nose Disease

Categories: Respiratory diseases, Smell/Taste diseases

Aliases & Classifications for Nose Disease

MalaCards integrated aliases for Nose Disease:

Name: Nose Disease 12 14
Nose Diseases 42 69
Abnormality of the Nose 29
Disorder of the Nose 12
Nasal Disorder 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2825
MeSH 42 D009668
SNOMED-CT 64 89488007
ICD10 33 J33.9
UMLS 69 C0028432

Summaries for Nose Disease

MalaCards based summary : Nose Disease, also known as nose diseases, is related to cytoplasmic body myopathy and x-linked intellectual disability, van esch type, and has symptoms including dyspnea and rhinorrhea. An important gene associated with Nose Disease is TRPV1 (Transient Receptor Potential Cation Channel Subfamily V Member 1), and among its related pathways/superpathways are Allograft rejection and Immune response Fc epsilon RI pathway. The drugs Amoxicillin and Cefditoren have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and eye, and related phenotypes are Increased transferrin (TF) endocytosis and hematopoietic system

Wikipedia : 72 The visible part of the human nose is the protruding part of the face that bears the nostrils. The shape... more...

Related Diseases for Nose Disease

Diseases related to Nose Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 186)
id Related Disease Score Top Affiliating Genes
1 cytoplasmic body myopathy 10.9 IL13 IL5
2 x-linked intellectual disability, van esch type 10.8 IL4 IL5 RNASE3
3 papillary follicular thyroid adenocarcinoma 10.8 IL5 RNASE3
4 orbital plasma cell granuloma 10.8 IL4 IL5 RNASE3
5 toxic diffuse goiter 10.8 IL13 IL5 RNASE3
6 myofibroma 10.8 IL13 IL5 TLR9
7 anterior dislocation of lens 10.8 CCL11 IL4 RNASE3
8 lymphocytic gastritis 10.8 CCL11 IL5 RNASE3
9 cannabis abuse 10.8 CCL11 IL5 RNASE3
10 acute necrotizing encephalopathy type 1 10.7 IL13 IL5 TLR9
11 tracheomalacia 10.7 CYSLTR1 RHNO1 TRPV1
12 abdominal tuberculosis 10.7 IL13 IL4 IL5
13 glucose intolerance 10.7 IL13 IL4 IL5
14 penis agenesis 10.7 CCL11 IL5
15 heart septal defect 10.7 CD79A RNASE3
16 spindle cell variant squamous cell breast carcinoma 10.7 IL13 IL4 IL5
17 aortic arch interruption 10.7 IL13 IL5
18 somatoform disorder 10.7 RNASE3 TAC1 TLR9
19 marasmus 10.7 IL4 IL5 RNASE3 TRPV1
20 malignant hyperthermia 10.7 IL4 IL5 TLR9
21 vulvar disease 10.7 CD79A RHNO1 RNASE3
22 acute ackee fruit intoxication 10.7 IL10 IL4
23 aniseikonia 10.6 CD79A IL4 RHNO1
24 cutaneous ganglioneuroma 10.6 CD79A IL4 RHNO1
25 acute vascular insufficiency of intestine 10.6 CD79A IL4 TLR9
26 placenta accreta 10.6 IL4 TAC1 TRPV1
27 philophthalmiasis 10.6 CD79A IL4 IL5
28 mikulicz disease 10.6 CD79A IL4 TLR9
29 epidermolysis bullosa simplex superficialis 10.6 CD79A IL4 RNASE3
30 winchester syndrome 10.6 IL13 IL4 IL5 RNASE3
31 purpura fulminans 10.6 IL13 IL4 IL5 RNASE3
32 acute gonococcal prostatitis 10.6 IL13 IL4 IL5 RNASE3
33 malignant renovascular hypertension 10.6 CD79A TAC1
34 exophthalmos 10.6 CXCL8 IL5 RNASE3
35 eye accommodation disease 10.6 IL10 IL4
36 whistling face syndrome, recessive form 10.6 CXCL8 IL5 RNASE3
37 combined thymoma 10.6 CD79A MUC5B
38 anti-basement membrane glomerulonephritis 10.6 CD79A CXCL8
39 pseudoainhum 10.6 RNASE3 TAC1
40 frontal sinus schneiderian papilloma 10.6 IL13 IL5 TRPV1 TSLP
41 endocardium cancer 10.6 CCL11 IL13 IL5 RNASE3
42 spondylolysis 10.6 CXCL8 TLR9 TRPV1
43 psychotic disorder 10.6 CCL11 CXCL8 IL4
44 dioctophymiasis 10.6 CCL11 IL13 IL4 IL5
45 epididymis adenocarcinoma 10.6 CCL11 IL13 IL4 IL5
46 retinal vascular disease 10.6 CCL11 CXCL8 IL4
47 subcorneal pustular dermatosis 10.6 CCL11 CD79A IL4
48 fungal gastritis 10.6 CCL11 IL13 IL4 IL5
49 vascular dementia 10.6 IL10 IL4 TLR9
50 cystadenocarcinoma 10.6 IL10 IL13

Graphical network of the top 20 diseases related to Nose Disease:



Diseases related to Nose Disease

Symptoms & Phenotypes for Nose Disease

UMLS symptoms related to Nose Disease:


dyspnea, rhinorrhea

GenomeRNAi Phenotypes related to Nose Disease according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased transferrin (TF) endocytosis GR00363-A 9.4 CD79A CXCL8 CYSLTR1 HRH1 IL10 IL13

MGI Mouse Phenotypes related to Nose Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.07 CCL11 CD79A CHD7 HRH1 IL10 IL13
2 homeostasis/metabolism MP:0005376 9.97 IL4 IL5 MUC5B PDCL PTGDR2 TLR9
3 digestive/alimentary MP:0005381 9.87 CHD7 IL10 IL13 IL4 IL5 TLR9
4 immune system MP:0005387 9.83 TRPV1 TSLP CCL11 CD79A CHD7 CYSLTR1
5 respiratory system MP:0005388 9.28 CCL11 CHD7 CYSLTR1 IL10 IL13 IL4

Drugs & Therapeutics for Nose Disease

Drugs for Nose Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 838)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 3,Phase 2 26787-78-0 33613 2171
2
Cefditoren Approved Phase 4 117467-28-4, 104145-95-1 9571074 9870843
3
Dexlansoprazole Approved Phase 4,Phase 3 138530-94-6, 103577-45-3 9578005
4
Lansoprazole Approved, Investigational Phase 4,Phase 3 103577-45-3 3883
5
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
6
Remifentanil Approved Phase 4,Phase 3 132875-61-7 60815
7
Rocuronium Approved Phase 4,Phase 3 119302-91-9, 143558-00-3 441290
8
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
9
Histamine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 75614-87-8, 51-45-6 774
10
Capsaicin Approved Phase 4,Phase 2,Phase 1 404-86-4 1548943
11
Montelukast Approved Phase 4,Phase 3,Phase 2,Phase 1 158966-92-8 5281040
12
Azelastine Approved Phase 4,Phase 3,Phase 2,Phase 1 58581-89-8 2267
13
Ephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 299-42-3 9294
14
Methylprednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 83-43-2 6741
15
Prednisolone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-24-8 5755
16
Pseudoephedrine Approved Phase 4,Phase 3,Phase 2,Phase 1 90-82-4 7028
17
Xylometazoline Approved Phase 4 526-36-3 5709
18
Cetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 83881-51-0 2678
19
Levocetirizine Approved Phase 4,Phase 3,Phase 2,Phase 1 130018-77-8
20
Nitric Oxide Approved Phase 4,Phase 2,Phase 3,Phase 1 10102-43-9 145068
21
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 76631-46-4, 113775-47-6 68602 5311068 56032
22
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3 2078-54-8 4943
23
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
24
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
25
Prednisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 53-03-2 5865
26
Desflurane Approved Phase 4 57041-67-5 42113
27
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2 51-43-4 5816
28 Racepinephrine Approved Phase 4,Phase 3,Phase 2
29
Heroin Approved, Illicit Phase 4,Phase 1 561-27-3 5462328
30
Naloxone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 465-65-6 5284596
31
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 137-58-6 3676
32
Dopamine Approved Phase 4,Phase 2,Phase 3,Phase 1 51-61-6, 62-31-7 681
33
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Phase 2 124-94-7 31307
34
Oxymetazoline Approved Phase 4,Phase 3,Phase 2,Phase 1 1491-59-4 4636
35
Phenylephrine Approved Phase 4,Phase 3,Phase 2,Phase 1 59-42-7 6041
36
Loratadine Approved Phase 4,Phase 3,Phase 2 79794-75-5 3957
37
Desloratadine Approved, Investigational Phase 4,Phase 3,Phase 2 100643-71-8 124087
38
Omalizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 242138-07-4
39
Betamethasone Approved, Vet_approved Phase 4,Phase 3 378-44-9 9782
40
Oxytocin Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-56-6 439302 53477758
41
Atropine Approved, Vet_approved Phase 4,Phase 2,Phase 1 5908-99-6, 51-55-8 174174
42
Mupirocin Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 12650-69-0 446596
43
Chlorhexidine Approved, Vet_approved Phase 4,Phase 3 55-56-1 9552079 2713
44
Nicotine Approved Phase 4,Phase 1,Phase 2 54-11-5 942 89594
45
Bevacizumab Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 216974-75-3
46
Menthol Approved Phase 4,Phase 2,Phase 1 2216-51-5 16666
47
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 437-38-7 3345
48
Budesonide Approved Phase 4,Phase 2,Phase 3,Phase 1 51333-22-3 63006 5281004
49
Ketamine Approved, Vet_approved Phase 4,Phase 2,Phase 3 6740-88-1 3821
50
Acetaminophen Approved Phase 4,Phase 3,Phase 2 103-90-2 1983

Interventional clinical trials:

(show top 50) (show all 2462)

id Name Status NCT ID Phase Drugs
1 Middle Meatal Bacteriology During Acute Respiratory Infection in Children Unknown status NCT00545961 Phase 4 placebo;amoxicillin clavulanate acid
2 An Open-label Study to Identify Molecular Markers of Steroid Resistance Unknown status NCT01616160 Phase 4 mometasone furoate
3 A Prospective Randomised Controlled Trial of Management of Recurrent Nosebleeds in Children Unknown status NCT00390663 Phase 4
4 Study of Cefditoren Pivoxil in Treatment of Childhood With Acute Rhinosinusitis Unknown status NCT01553006 Phase 4 cefditoren pivoxil
5 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
6 Remifentanil and Controlled Hypotension for Functional Endoscopic Sinus Surgery: Comparison With Tramadol and Metoprolol Unknown status NCT02484859 Phase 4 Remifentanil;Tramadol;Metoprolol
7 Immunological Mechanisms of Oralair® in Patients With Seasonal Allergic Rhinitis Unknown status NCT02014623 Phase 4 Control
8 Comparative Study of Sinol and Sinol-M in Patients With Congestion Due to Allergic Rhinitis Unknown status NCT00825656 Phase 4 Sinol or Sinol-M nasal spray
9 Singulair Use in Non-Allergic Rhinitis Eosinophil Syndrome (NARES) Unknown status NCT00406094 Phase 4 montelukast;placebo
10 Efficacy of Allergen Immunotherapy for Allergic Rhinitis in Thais Unknown status NCT01115595 Phase 4
11 4"S" - Seasonal Symptoms Suppression Study Unknown status NCT02557269 Phase 4 Xylometazoline - intranasal application;Azelastine - intranasal application;Mometasone furoate - intranasal application;Hydroxyl-propyl-methyl cellulose powder - intranasal application;Bilastine 20 mg;Prednisolone 5 mg
12 Cosalin® Monotherapy Versus Cosalin® and Xarlin® Combination Therapy Unknown status NCT01062139 Phase 4 Xarlin (Levocetirizine);Cosalin (Petasites hybridus CO2 extract)
13 Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis Unknown status NCT00488176 Phase 4 montelukast;cetirizine;montelukast and cetirizine;placebo
14 POLlinosis and Exhaled Breath Temperature Unknown status NCT01785394 Phase 4 5 grass allergen extract
15 Comparison of Daily Mometasone Furoate Nasal Spray Alone Versus a Combination With Montelukast for Treatment of Chronic Rhinosinusitis With Asthma After Functional Endoscopic Sinus Surgery Unknown status NCT02110654 Phase 4 Montelukast;mometasone furoate nasal spray
16 Assessment of Sublingual Immunotherapy in Children Allergic to House Dust Mites Unknown status NCT01052610 Phase 4 sublingual house dust mites allergen extract;placebo in sublingual applicator
17 Effect of Deksmedetomidine and Remifentanil in Extubation Agitation Unknown status NCT02104297 Phase 4 deksmedetomidine;Remifentanil;Saline
18 Anesthesia Induction in Patients Undergoing Surgery for Cervical Myelopathy Unknown status NCT01052337 Phase 4 anaesthetics: sevofluorane
19 A Comparison of Esmolol and Remifentanil to Reduce Blood Loss Unknown status NCT01752959 Phase 4 Remifentanil;Esmolol
20 Nasal Continuous Positive Airway Pressure (CPAP) in Chronic Fatigue and Sleep-disordered Breathing Unknown status NCT01368718 Phase 4
21 Cpap at Delivery Room for Preterm Infants Unknown status NCT01024361 Phase 4
22 Inflammatory, Functional and Image Composite Measure to Define Asthma Control Unknown status NCT00597064 Phase 4 prednisone
23 Comparision Between Hemodynamic Response of Dexmedetomidine and Remifentanil on Anesthesia in Endoscopic Sinus Surgery Unknown status NCT02464722 Phase 4 Dexmedetomidine;Remifentanil;Epinephrine;Propofol;Rocuronium
24 Bronchiolitis All-study, SE-Norway Unknown status NCT00817466 Phase 4 Racemic adrenaline;Isotonic saline
25 Nasal Naloxone for Narcotic Overdose Unknown status NCT01912573 Phase 4 Intranasal (IN) naloxone;Intravenous (IV) naloxone;Intramuscular (IM) naloxone;Intraosseus (IO) naloxone
26 The Efficacy and Safety of Hyeonggaeyeongyo-tang for Chronic Rhinitis According to Pattern Identification in Korean Medicine Completed NCT02477293 Phase 4 Hyeonggaeyeongyo-tang
27 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device Completed NCT02079792 Phase 4
28 Fluticasone and Salmeterol in Allergic Rhinitis Completed NCT01388595 Phase 4 FLUTICASONE PROPRIONATE;Salmeterol;PLACEBO
29 Effect of Ketamine Addition to Lidocaine in Rhinoplasty Completed NCT01827020 Phase 4 Lidocaine 2 %;Ketamine plus Lidocaine;Saline
30 Evaluation Of Cloumella Strut Effect In Tip Rotation Completed NCT00467714 Phase 4
31 Neuro-immunological Analysis of Idiopathic Rhinitis Patients and Controls Treated With Capsaicin. Completed NCT01223820 Phase 4 Capsaicin
32 Mechanisms of Capsaicin Treatment in Idiopathic Rhinitis Patients and Controls Completed NCT01862523 Phase 4
33 Safety and Efficacy of Olopatadine 0.6% and Azelastine 137 Mcg in Vasomotor Rhinitis Completed NCT00979615 Phase 4 Olopatadine HCL (Patanase) Nasal Spray, 0.6%;Azelastine HCl (Astelin) Nasal Spray, 137 mcg
34 Treatment of Acute Sinusitis Completed NCT00377403 Phase 4 Acetaminophen;Amoxicillin;Dextromethorphan hydrobromide with guaifenesin;Guaifenesin;Pseudoephedrine Sustained Action;Saline spray (0.65%)
35 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis Completed NCT00396162 Phase 4 probiotic containing L.rhamnosus R0011 strain
36 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
37 The PIO II Study of In-office Placement of a Steroid-eluting Sinus Implant Completed NCT02668302 Phase 4
38 Sinuclean's Treatment Of Sinusitis' Symptoms Completed NCT00747747 Phase 4
39 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel Completed NCT00554190 Phase 4
40 Saline Irrigation After Surgery in Patients With Chronic Sinusitis Completed NCT01575223 Phase 4
41 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery Completed NCT01706952 Phase 4 Cocaine;Adrenaline
42 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis Completed NCT01825408 Phase 4 Doxycycline;Azithromycin;Augmentin
43 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis Completed NCT02296814 Phase 4 Sinusitis Hevert SL Tablet;Placebo for Sinusitis Hevert SL Tablet
44 Systemic Methylprednisolone in Chronic Rhinosinusitis Completed NCT01205984 Phase 4 methylprednisolone
45 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate Completed NCT02340000 Phase 4 standard dose amoxicillin/clavulanate;high dose amoxicillin/clavulanate
46 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery Completed NCT01569048 Phase 4 Propofol and dexmedetomidine;propofol and remifentanil
47 Medicated Punctured-Glove-Finger Spacer Study Completed NCT01420471 Phase 4 Triamcinolone
48 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox Completed NCT00668304 Phase 4 Avelox (Moxifloxacin, BAY12-8039)
49 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis Completed NCT00645073 Phase 4 cefdinir (Omnicef);levofloxacin
50 Zmax Compared to Augmentin in Sinusitis Completed NCT00367120 Phase 4 Azithromycin Extended Release;Amoxicillin/Clavulanate

Search NIH Clinical Center for Nose Disease

Cochrane evidence based reviews: nose diseases

Genetic Tests for Nose Disease

Genetic tests related to Nose Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Nose 29

Anatomical Context for Nose Disease

MalaCards organs/tissues related to Nose Disease:

39
Lung, Testes, Eye, Skin, Colon, Brain, Bone

Publications for Nose Disease

Articles related to Nose Disease:

id Title Authors Year
1
Blue nose disease in the horse. ( 18124494 )
1949

Variations for Nose Disease

Expression for Nose Disease

Search GEO for disease gene expression data for Nose Disease.

Pathways for Nose Disease

Pathways related to Nose Disease according to GeneCards Suite gene sharing:

(show all 23)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
12.6 CCL11 CXCL8 IL10 IL13 IL4 IL5
2
Show member pathways
12.51 CD79A IL13 IL4 IL5 MS4A2
3
Show member pathways
12.27 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
4
Show member pathways
12.2 IL10 IL13 IL4 IL5 TSLP
5
Show member pathways
12.12 CCL11 CXCL8 IL4 TLR9
6
Show member pathways
12.12 CXCL8 IL10 IL13 IL4 IL5
7 12.11 CXCL8 IL10 IL13 TAC1
8 11.96 CD79A IL10 IL4 IL5 PTGDR2
9 11.93 CCL11 CXCL8 IL10 IL13 IL4
10 11.79 CXCL8 IL13 IL4 IL5
11 11.7 IL10 IL4 IL5 TLR9
12
Show member pathways
11.67 CXCL8 IL4 IL5
13 11.65 CCL11 IL10 IL4 IL5
14 11.52 CXCL8 IL10 IL13 IL4
15 11.46 CXCL8 IL10 TLR9
16 11.34 IL10 IL13 IL4 IL5 PTGDR2 TSLP
17 11.24 IL13 IL4 IL5 TSLP
18 11.23 CCL11 IL10 IL13 IL4 IL5
19 11.18 IL10 IL13 IL4 IL5
20 11.08 CCL11 CXCL8 IL10 IL13 IL4 IL5
21 11.04 IL10 IL13 IL4 IL5
22 10.9 CCL11 CXCL8 IL13 IL4 IL5 MUC5B
23 10.89 IL13 IL4 IL5

GO Terms for Nose Disease

Cellular components related to Nose Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.7 CCL11 CXCL8 IL10 IL13 IL4 IL5
2 external side of plasma membrane GO:0009897 9.55 CD79A IL13 IL4 MS4A2 TRPV1
3 extracellular space GO:0005615 9.36 CCL11 CXCL8 IL10 IL13 IL4 IL5

Biological processes related to Nose Disease according to GeneCards Suite gene sharing:

(show all 19)
id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.88 CD79A CYSLTR1 MS4A2 TRPV1
2 chemotaxis GO:0006935 9.77 CCL11 CXCL8 CYSLTR1 IL4 PTGDR2
3 B cell differentiation GO:0030183 9.74 CD79A IL10 IL4
4 negative regulation of endothelial cell apoptotic process GO:2000352 9.61 IL10 IL13 IL4
5 positive regulation of mast cell degranulation GO:0043306 9.58 IL13 IL4
6 microglial cell activation GO:0001774 9.58 IL13 IL4 TRPV1
7 eosinophil chemotaxis GO:0048245 9.56 CCL11 HRH1
8 immune response GO:0006955 9.56 CCL11 CXCL8 IL10 IL13 IL4 IL5
9 positive regulation of MHC class II biosynthetic process GO:0045348 9.55 IL10 IL4
10 type 2 immune response GO:0042092 9.52 IL10 IL4
11 negative regulation of interleukin-8 production GO:0032717 9.51 IL10 TLR9
12 response to molecule of bacterial origin GO:0002237 9.5 CXCL8 IL10 TLR9
13 regulation of isotype switching GO:0045191 9.49 IL10 IL4
14 regulation of proton transport GO:0010155 9.48 IL13 IL4
15 negative regulation of complement-dependent cytotoxicity GO:1903660 9.46 IL13 IL4
16 positive regulation of B cell proliferation GO:0030890 9.33 IL13 IL4 IL5
17 inflammatory response GO:0006954 9.32 CCL11 CXCL8 HRH1 IL10 IL13 IL5
18 positive regulation of immunoglobulin production GO:0002639 9.26 IL13 IL4
19 signal transduction GO:0007165 10.19 CCL11 CXCL8 CYSLTR1 HRH1 IL13 MS4A2

Molecular functions related to Nose Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.17 CCL11 CXCL8 IL10 IL13 IL4 IL5

Sources for Nose Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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