MCID: NVS004
MIFTS: 15

Nova Syndrome

Categories: Rare diseases

Aliases & Classifications for Nova Syndrome

MalaCards integrated aliases for Nova Syndrome:

Name: Nova Syndrome 50 56
Port-Wine Nevi-Mega Cisterna Magna-Hydrocephalus Syndrome 56
Port Wine Nevi Mega Cisterna Magna Hydrocephalus 50

Classifications:



External Ids:

Orphanet 56 ORPHA2703

Summaries for Nova Syndrome

MalaCards based summary : Nova Syndrome, is also known as port-wine nevi-mega cisterna magna-hydrocephalus syndrome. The drugs Dopamine and Rivaroxaban have been mentioned in the context of this disorder. Affiliated tissues include heart, myeloid and testes.

Related Diseases for Nova Syndrome

Symptoms & Phenotypes for Nova Syndrome

Drugs & Therapeutics for Nova Syndrome

Drugs for Nova Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 345)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4,Phase 3,Phase 2 51-61-6, 62-31-7 681
2
Rivaroxaban Approved Phase 4,Phase 3 366789-02-8
3
Interferon beta-1a Approved, Investigational Phase 4 145258-61-3 6438354
4
Protein C Approved Phase 4
5
Lopinavir Approved Phase 4 192725-17-0 92727
6
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
7
Risperidone Approved, Investigational Phase 4 106266-06-2 5073
8
Ritonavir Approved, Investigational Phase 4,Phase 2,Phase 3 155213-67-5 392622
9
Aspirin Approved, Vet_approved Phase 4,Phase 3 50-78-2 2244
10
Somatostatin Approved Phase 4,Phase 3,Phase 2 38916-34-6, 51110-01-1 53481605
11
Emtricitabine Approved, Investigational Phase 4,Phase 3 143491-57-0 60877
12
Apixaban Approved Phase 4,Phase 3 503612-47-3 10182969
13
Eluxadoline Approved Phase 4 864821-90-9
14
Loperamide Approved Phase 4 53179-11-6 3955
15
Ziprasidone Approved Phase 4,Phase 3 146939-27-7 60854
16
Lamivudine Approved, Investigational Phase 4 134678-17-4 60825
17
Menadione Approved, Nutraceutical Phase 4 58-27-5 4055
18
Phytonadione Approved, Nutraceutical Phase 4 84-80-0 4812 5284607
19
Lactitol Investigational Phase 4 585-86-4 3871
20 Dopamine Agents Phase 4,Phase 3,Phase 2
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
22 Neurotransmitter Uptake Inhibitors Phase 4,Phase 3,Phase 2
23 Micronutrients Phase 4,Phase 3,Phase 2
24 Trace Elements Phase 4,Phase 3,Phase 2
25 Hormone Antagonists Phase 4,Phase 3,Phase 2
26 Hormones Phase 4,Phase 3,Phase 2
27 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2
28 Antibodies Phase 4,Phase 3,Phase 1
29 Antibodies, Antiphospholipid Phase 4
30 Anticoagulants Phase 4,Phase 3,Phase 2
31 Antithrombin III Phase 4,Phase 3
32 Antithrombins Phase 4,Phase 3
33 Factor Xa Inhibitors Phase 4,Phase 3
34 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
35 Immunoglobulins Phase 4,Phase 3,Phase 1
36
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
37 Serine Proteinase Inhibitors Phase 4,Phase 3,Phase 1,Phase 2
38 Adjuvants, Immunologic Phase 4,Phase 3,Phase 2
39 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
40 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
41 Interferon-beta Phase 4,Phase 3
42 interferons Phase 4,Phase 3
43 Drotrecogin alfa activated Phase 4
44 Fibrinolytic Agents Phase 4,Phase 3,Phase 2
45 Anti-HIV Agents Phase 4,Phase 3,Phase 2
46 Anti-Retroviral Agents Phase 4,Phase 3,Phase 2
47 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
48 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 3,Phase 2
49 Antipsychotic Agents Phase 4,Phase 3
50 Central Nervous System Depressants Phase 4,Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 179)

id Name Status NCT ID Phase Drugs
1 The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study Unknown status NCT01623193 Phase 4
2 Rivaroxaban for Antiphospholipid Antibody Syndrome Completed NCT02116036 Phase 4 Rivaroxaban
3 Long Term Study of Avonex Therapy Following a First Attack of Multiple Sclerosis Completed NCT00179478 Phase 4 interferon beta 1a 30 ug IM once weekly
4 The Study of Drotrecogin Alfa (Activated) in a Subpopulation of Adult Patients With Severe Sepsis Completed NCT00045760 Phase 4 Drotrecogin alfa (activated)
5 Lopinavir/r Monotherapy as Maintenance Therapy After Long Term Viral Suppression Completed NCT00160849 Phase 4 Lopinavir/r
6 A Trial Comparing Risperidone Long-Acting Injection With Oral Antipsychotic in the Treatment of Early Psychosis Completed NCT00246259 Phase 4 Risperidone long-acting injection (LAI);Oral Antipsychotic
7 Pharmacokinetics of the Tablet Formulation of Lopinavir/r as Standard and Increased Dosage During Pregnancy Completed NCT00605098 Phase 4 Lopinavir / ritonavir;Lopinavir/ritonavir
8 Rapid Evaluation of Pandemic H1N1 Influenza Vaccine in Adults With HIV Completed NCT01002040 Phase 4
9 Comparing the Effect of Under the Tongue Olanzapine Versus Swallowed Olanzapine on Body Mass Index (A Ratio of Weight to Height) Completed NCT00303602 Phase 4 Sublingual orally disintegrating olanzapine (SODO);Oral olanzapine
10 A Study of Apixaban in Patients With Atrial Fibrillation, Not Caused by a Heart Valve Problem, Who Are at Risk for Thrombosis (Blood Clots) Due to Having Had a Recent Coronary Event, Such as a Heart Attack or a Procedure to Open the Vessels of the Heart Recruiting NCT02415400 Phase 4 Apixaban;vitamin K antagonist;Acetylsalicylic acid
11 Efficacy of Eluxadoline in the Treatment of Irritable Bowel Syndrome With Diarrhea in Patients With Inadequate Control of Symptoms With Prior Loperamide Use Recruiting NCT02959983 Phase 4 Eluxadoline;Placebo
12 Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in a Novartis-sponsored Study. Recruiting NCT01794793 Phase 4 Pasireotide
13 Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart Failure Recruiting NCT01128816 Phase 4
14 One-Year Trial Of Oral Ziprasidone In Patients With Metabolic Syndrome Terminated NCT00748566 Phase 4 Ziprasidone HCL (oral)
15 Evaluation of 3TC or FTC Mono-therapy Compared to Continuing HAART as a Bridging Strategy Terminated NCT01338025 Phase 4 HAART regimen;3TC or FTC monotherapy
16 A Study of Risperidone Long-Acting Injection Versus Oral Antipsychotics in Schizophrenia Participants With a History of Being Poorly Compliant With Taking Their Medication Terminated NCT00256997 Phase 4 Risperidone long-acting injection (LAI);Oral atypical Antipsychotic
17 Effect of Bromocriptine on Insulin Resistance in Polycystic Ovarian Syndrome - A Pilot Study Unknown status NCT02133755 Phase 3 Bromocriptine
18 Thymoglobulin in Unrelated Hematopoietic Progenitor Cell Transplantation Unknown status NCT01217723 Phase 3
19 Double-Masked Trial of NOVA22007 (Ciclosporin 0.1%) Versus Vehicle in Patients With Moderate to Severe Dry Eye Syndrome Completed NCT00814515 Phase 3 NOVA22007 (Ciclosporin 0.1%);NOVA22007
20 Follow-up at School-age of Children Who Participated in the Efficacy Study of Nitric Oxide for Premature Infants Completed NCT00152542 Phase 3 Inhaled nitric oxide;Placebo
21 Evaluation of Varenicline (Champix) in Smoking Cessation for Patients Post-Acute Coronary Syndrome (EVITA) Trial Completed NCT00794573 Phase 3 varenicline
22 Efficacy, Safety, and Tolerability of JNJ-27018966 in the Treatment of Patients With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) (Protocol JNJ-27018966IBS3001) Completed NCT01553591 Phase 3 JNJ-27018966;Placebo
23 Sibling Donor Peripheral Stem Cell Transplant or Sibling Donor Bone Marrow Transplant in Treating Patients With Hematologic Cancers or Other Diseases Completed NCT00438958 Phase 3
24 A Study With Aleglitazar in Patients With a Recent Acute Coronary Syndrome and Type 2 Diabetes Mellitus Completed NCT01042769 Phase 3 Aleglitazar;Placebo
25 A Comparison of Ticagrelor (AZD6140) and Clopidogrel in Patients With Acute Coronary Syndrome Completed NCT00391872 Phase 3 Ticagrelor;Clopidogrel
26 Ropinirole XR (Extended Release) In Patients With Restless Legs Syndrome Completed NCT00197080 Phase 3 Ropinirole Extended Release (XR)
27 Somatropin Treatment to Final Height in Turner Syndrome Completed NCT00191113 Phase 3 Somatropin;Ethinyl estradiol;Medroxyprogesterone acetate
28 The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome Completed NCT00143598 Phase 3
29 A Comparison of Prasugrel and Clopidogrel in Acute Coronary Syndrome Subjects Completed NCT00699998 Phase 3 Clopidogrel;Prasugrel;Commercially-available Aspirin
30 An Efficacy and Safety Study for Rivaroxaban in Patients With Acute Coronary Syndrome Completed NCT00809965 Phase 3 Rivaroxaban 2.5 mg;Rivaroxaban 5 mg;Placebo;Standard of care
31 Telotristat Etiprate for Carcinoid Syndrome Therapy Completed NCT02063659 Phase 3 Telotristat etiprate tablets (250 mg);Placebo
32 Cardiovascular Outcomes Study of Alogliptin in Patients With Type 2 Diabetes and Acute Coronary Syndrome Completed NCT00968708 Phase 3 Alogliptin;Placebo
33 A Study of RO4607381 in Stable Coronary Heart Disease Patients With Recent Acute Coronary Syndrome Completed NCT00658515 Phase 3 Dalcetrapib (RO4607381);Evidence-based medical care for Acute Coronary Syndrome;Placebo
34 Chemotherapy in Treating Children With Down Syndrome and Myeloproliferative Disorder, Acute Myelogenous Leukemia, or Myelodysplastic Syndrome Completed NCT00003593 Phase 3 asparaginase;cytarabine;daunorubicin hydrochloride;methotrexate;therapeutic hydrocortisone;thioguanine
35 Effects in The ApoB/ApoA-I Ratio Using Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome Completed NCT00296387 Phase 3 Rosuvastatin;Atorvastatin
36 Minocycline in Clinically Isolated Syndromes (CIS) Completed NCT00666887 Phase 3 Minocycline;Placebo
37 TELESTAR (Telotristat Etiprate for Somatostatin Analogue Not Adequately Controlled Carcinoid Syndrome) Completed NCT01677910 Phase 3 Telotristat etiprate tablets (250 mg);Placebo tablets
38 Zyban as an Effective Smoking Cessation Aid for Patients Following an Acute Coronary Syndrome: The ZESCA Trial Completed NCT00689611 Phase 3 Bupropion HCl ER;Placebo
39 The Stabilization Of pLaques usIng Darapladib-Thrombolysis In Myocardial Infarction 52 Trial Completed NCT01000727 Phase 3 Darapladib 160 mg;Placebo
40 Biomarker Sub Study of the Compression Stockings to Prevent the Post-Thrombotic Syndrome (SOX) Trial Completed NCT01615705 Phase 3
41 A Multicenter, Randomized, Open Label Trial of a New Animal Extracted Surfactant to Treat RDS in Preterm Infants Completed NCT02305160 Phase 2, Phase 3 Butantan;Control
42 Multicenter, Safety Study Of Maraviroc Completed NCT00478231 Phase 3 Maraviroc
43 Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma Completed NCT00033293 Phase 3 cyclophosphamide;prednisone;Corticotropin-Releasing Hormone
44 A Study of RO4917838 (Bitopertin) in Patients With Sub-optimally Controlled Symptoms of Schizophrenia (WN25306) Completed NCT01235585 Phase 3 Placebo;bitopertin [RO4917838];bitopertin [RO4917838]
45 Rollover Trial Safety and Tolerability of Combination Tipranavir and Ritonavir Use in HIV 1 Infected Subjects Completed NCT00146328 Phase 2, Phase 3 Tipranavir
46 Combination Chemotherapy With or Without Gemtuzumab in Treating Young Patients With Newly Diagnosed Acute Myeloid Leukemia Completed NCT00372593 Phase 3 asparaginase;cytarabine;daunorubicin hydrochloride;etoposide;gemtuzumab ozogamicin;mitoxantrone hydrochloride
47 Safety and Tolerability of Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder Completed NCT01727713 Phase 3 Aripiprazole
48 Study Evaluating the Safety and Efficacy of Fixed-dose Once-daily Oral Aripiprazole in Children and Adolescents With Tourette's Disorder Completed NCT01727700 Phase 3 Aripiprazole;Placebo
49 Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors Completed NCT00566852 Phase 3 Memantine
50 Safinamide in Idiopathic Parkinson's Disease (IPD) With Motor Fluctuations, as add-on to Levodopa Completed NCT00627640 Phase 3 Safinimide 50-100 mg/day;Matching Placebo

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Genetic Tests for Nova Syndrome

Anatomical Context for Nova Syndrome

MalaCards organs/tissues related to Nova Syndrome:

39
Heart, Myeloid, Testes, Eye, Brain, Lung, Bone

Publications for Nova Syndrome

Variations for Nova Syndrome

Expression for Nova Syndrome

Search GEO for disease gene expression data for Nova Syndrome.

Pathways for Nova Syndrome

GO Terms for Nova Syndrome

Sources for Nova Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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