MCID: OBS002
MIFTS: 73

Obsessive-Compulsive Disorder malady

Mental diseases, Neuronal diseases categories
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Summaries for Obsessive-Compulsive Disorder

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MedlinePlus:33 Obsessive-compulsive disorder (ocd) is a type of anxiety disorder. if you have ocd, you have frequent, upsetting thoughts called obsessions. to try to control the thoughts, you feel an overwhelming urge to repeat certain rituals or behaviors. these are called compulsions. examples of obsessions are a fear of germs or a fear of being hurt. compulsions include washing your hands, counting, checking on things, or cleaning. with ocd, the thoughts and rituals cause distress and get in the way of your daily life. researchers think brain circuits may not work properly in people who have ocd. it tends to run in families. the symptoms often begin in children or teens. treatments include therapy, medicines, or both. one type of therapy, cognitive behavioral therapy, is useful for treating ocd. nih: national institute of mental health

MalaCards based summary: Obsessive-Compulsive Disorder, also known as obsessive compulsive disorder, is related to schizophrenia and generalized anxiety disorder. An important gene associated with Obsessive-Compulsive Disorder is SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4), and among its related pathways are Hypothetical Network for Drug Addiction and Monoamine Transport. The drugs citalopram and citalopram hydrobromide and the compounds mhpg and methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include brain, cortex and testes, and related mouse phenotypes are muscle and growth/size/body.

Disease Ontology:8 An anxiety disorder that involves unwanted and repeated thoughts, feelings, ideas, sensations (obsessions), or behaviors that make them feel driven to do something (compulsions).

Wikipedia:65 Obsessive?compulsive disorder (OCD) is an anxiety disorder characterized by intrusive thoughts that... more...

Description from OMIM:46 164230

Aliases & Classifications for Obsessive-Compulsive Disorder

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Sources:
8Disease Ontology, 22GTR, 46OMIM, 44Novoseek, 33MedlinePlus, 62UMLS, 27ICD9CM, 34MeSH, 57SNOMED-CT, 25ICD10
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Obsessive-Compulsive Disorder, Aliases & Descriptions:

Name: Obsessive-Compulsive Disorder 8 46 44 33 62
Obsessive Compulsive Disorder 8 22
 
Anancastic Neurosis 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Mental diseases, Neuronal diseases


External Ids:

Disease Ontology8 DOID:10933
ICD9CM27 300.3
MeSH34 D009771
ICD1025 F42

Related Diseases for Obsessive-Compulsive Disorder

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Diseases related to Obsessive-Compulsive Disorder via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 173)
idRelated DiseaseScoreTop Affiliating Genes
1schizophrenia31.9COMT, HTR2A
2generalized anxiety disorder31.7HTR1A, SLC6A4
3pathological gambling31.7DRD4, DRD1
4anorexia nervosa31.7HTR2A, BDNF
5gilles de la tourette syndrome31.5DRD4
6panic disorder31.4SLC6A4, HTR1A, HTR3A
7bipolar disorder31.2HTR2A, HTR3A, SLC6A4
8intermittent explosive disorder31.1HTR1B
9agoraphobia31.1MAOA, HTR1A
10personality disorder31.1TPH1, HTR1B, MAOA, DRD4, SLC6A4
11paranoid schizophrenia31.1COMT
12autistic disorder31.0DRD4, BDNF, SLC6A4
13anxiety disorder30.9TPH1, HTR3A, MAOA, BDNF, SLC6A4
14schizoaffective disorder30.8HTR2A, COMT, DRD4, BDNF, SLC6A4
15narcolepsy30.7DRD1, COMT, HTR2A
16dysthymic disorder30.6HTR2A, MAOA
17eating disorder30.6HTR2A, HTR3A, HTR1A, COMT, BDNF, SLC6A4
18drug addiction30.6PDYN, DRD1, BDNF
19seasonal affective disorder30.5TPH1, HTR2A, HTR1A, DRD4, SLC6A4
20social phobia30.5HTR3A, HTR1A, COMT, MAOA, SLC6A4
21temporal lobe epilepsy30.4HTR1A, PDYN, BDNF, SLC1A1
22drug dependence30.3SLC6A4, PDYN, MAOA
23memory impairment30.2HTR2A, HTR1A, PDYN, DRD1, BDNF
24alcohol dependence30.2HTR2A, HTR1B, MAOA, DRD4, DRD1, SLC6A4
25attention deficit hyperactivity disorder30.1HTR2A, HTR1B, COMT, MAOA, DRD4, DRD1
26serotonin syndrome30.0HTR2A, HTR3A, HTR1A, MAOA
27parkinson's disease29.8HTR1A, COMT, MAOA, PDYN, BDNF
28bulimia nervosa29.8HTR2A, HTR1B, HTR3A, COMT, MAOA, BDNF
29mental retardation29.7TPH1, HTR3A, COMT, MAOA, BDNF
30dementia29.2HTR2A, HTR3A, HTT, HTR1A, COMT, MAOA
31mood disorder28.8DRD4, DRD1, BDNF, SLC6A4, PDYN, MAOA
32migraine28.7HTR3A, HTR1A, COMT, MAOA, DRD4, DRD1
33psychotic disorder28.6TPH1, HTR2A, HTR3A, HTR1A, COMT, MAOA
34alzheimer's disease28.5HTR1A, COMT, MAOA, PDYN, DRD4, DRD1
35trichotillomania11.0
36body dysmorphic disorder11.0
37obsessive-compulsive personality disorder10.8
38hypochondriasis10.8
39tic disorder10.7
40blindness10.7
41neuronitis10.7
42chronic tic disorder10.6
43schizotypal personality disorder10.6
44major depressive disorder10.6
45alexithymia10.6
46dystonia10.6
47oppositional defiant disorder10.5DRD4
48heroin dependence10.5DRD4
49cerebritis10.5
50neuroacanthocytosis10.5

Graphical network of the top 20 diseases related to Obsessive-Compulsive Disorder:



Diseases related to obsessive-compulsive disorder

Symptoms for Obsessive-Compulsive Disorder

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Clinical features from OMIM:

164230

Drugs & Therapeutics for Obsessive-Compulsive Disorder

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Genetic Tests for Obsessive-Compulsive Disorder

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Genetic tests related to Obsessive-Compulsive Disorder:

id Genetic test Affiliating Genes
1 Obsessive-Compulsive Disorder22

Anatomical Context for Obsessive-Compulsive Disorder

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MalaCards organs/tissues related to Obsessive-Compulsive Disorder:

32
Brain, Cortex, Testes, Thalamus, Skin, Prefrontal cortex, Subthalamic nucleus, Pineal, Pituitary, Eye, B cells, Cingulate cortex, Temporal lobe, Hypothalamus, Amygdala, Pons

Animal Models for Obsessive-Compulsive Disorder or affiliated genes

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MGI Mouse Phenotypes related to Obsessive-Compulsive Disorder:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053697.6SGCE, TPH1, HTR2A, HTR1B, HTR3A, DRD1
2MP:00053787.1HTR1B, HTR3A, HTT, PDYN, DRD1, BDNF
3MP:00107717.1TPH1, HTR3A, HTT, PDYN, DRD1, BDNF
4MP:00053857.1SGCE, TPH1, HTR1B, HTT, HTR1A, COMT
5MP:00036315.6SGCE, HTR3A, HTT, HTR1A, COMT, MAOA
6MP:00053765.4COMT, HTR1A, HTT, HTR3A, TPH1, MAOA
7MP:00053864.7SLC1A1, SGCE, TPH1, HTR2A, HTR1B, HTR3A

Publications for Obsessive-Compulsive Disorder

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Articles related to Obsessive-Compulsive Disorder:

(show top 50)    (show all 901)
idTitleAuthorsYear
1
L-3,4-Dihydroxy-6-[F-18]fluorophenylalanine positron emission tomography demonstrating dopaminergic system abnormality in the brains of obsessive-compulsive disorder patients. (24405478)
2014
2
Paediatric Obsessive-Compulsive Disorder and Depressive Symptoms: Clinical Correlates and CBT Treatment Outcomes. (25301176)
2014
3
Moral rigidity in obsessive-compulsive disorder: do abnormalities in inhibitory control, cognitive flexibility and disgust play a role? (24161700)
2014
4
Doing Psychiatry Right: A Case of Severe Avoidant Personality Disorder with Obsessive-compulsive Personality Disorder, Obsessive Compulsive Disorder, Intermittent Explosive Disorder and Sexual Paraphilias. (25035563)
2014
5
Discontinuous patterns of brain activation in the psychotherapy process of obsessive-compulsive disorder: converging results from repeated FMRI and daily self-reports. (23977168)
2013
6
Clinical features of pure obsessive-compulsive disorder. (23746710)
2013
7
Incompleteness as a Link between Obsessive-Compulsive Personality Traits and Specific Symptom Dimensions of Obsessive-Compulsive Disorder. (23650140)
2013
8
Cognitive Behavioural Therapy for Obsessive-Compulsive Disorder with Comorbid Schizophrenia: A Case Report with Repetitive Measurements. (23899371)
2013
9
Buprenorphine augmentation in the treatment of refractory obsessive-compulsive disorder. (23983988)
2013
10
Brain corticostriatal systems and the major clinical symptom dimensions of obsessive-compulsive disorder. (23200527)
2013
11
Pediatric obsessive-compulsive disorder: a review for nursing professionals. (23607826)
2013
12
Obsessive-compulsive disorder and cingulotomy. (23746096)
2013
13
Default network connectivity as a vulnerability marker for obsessive compulsive disorder. (24001350)
2013
14
Cognitive deficits of executive functions and decision-making in obsessive-compulsive disorder. (23841985)
2013
15
Is there a Role for Immunological Mechanisms in Etiopathogenesis of Obsessive Compulsive Disorder? (23833334)
2013
16
The relationship between obsessive-compulsive personality disorder traits, obsessive-compulsive disorder and excessive exercise in patients with anorexia nervosa: a systematic review. (24999397)
2013
17
Obsessive-compulsive disorder in dermatology. (24049965)
2013
18
Obsessive compulsive disorder networks: positron emission tomography and neuropsychology provide new insights. (23326403)
2013
19
Symptom dimensions are associated with age of onset and clinical course of obsessive-compulsive disorder. (23410525)
2013
20
Association study between IL-1I^-511 C/T polymorphism and obsessive-compulsive disorder (OCD) in Chinese Han population. (24552038)
2013
21
Dissociative symptoms and dissociative disorder comorbidity in patients with obsessive-compulsive disorder. (22425531)
2012
22
Cognitive-behavioral therapy for obsessive-compulsive disorder as a comorbidity with schizophrenia or schizoaffective disorder. (22123432)
2012
23
Early sleep psychiatric intervention for acute insomnia: implications from a case of obsessive-compulsive disorder. (22505865)
2012
24
Contextual and behavioral influences on uncertainty in obsessive-compulsive disorder. (23318087)
2012
25
Schizophrenia and obsessive-compulsive disorder: from comorbidity to schizo-obsessive disorder. (22622247)
2012
26
Rage takes center stage: focus on an underappreciated aspect of pediatric obsessive-compulsive disorder. (22632616)
2012
27
Living with parents with obsessive-compulsive disorder: children's lives and experiences. (22903894)
2012
28
Sexual obsessions, compulsions, suicidality and homicidality in an adolescent diagnosed with bipolar disorder not otherwise specified, obsessive-compulsive disorder, pervasive developmental disorder not otherwise specified, and mild mental retardation. (22612525)
2012
29
Reduced serotonin transporter binding in the insular cortex in patients with obsessive-compulsive disorder: a [11C]DASB PET study. (19660554)
2010
30
Search for copy number variants in chromosomes 15q11-q13 and 22q11.2 in obsessive compulsive disorder. (20565924)
2010
31
Association study between the -62A/T NFKBIL1 polymorphism and obsessive-compulsive disorder. (19578685)
2009
32
Clozapine in treatment-refractory obsessive-compulsive disorder with comorbid schizotypal personality disorder. (19398826)
2008
33
Screening of the epsilon sarcoglycan gene in Tourette syndrome and obsessive compulsive disorder. (18349702)
2008
34
Association study between the dopamine receptor D(4) gene and obsessive-compulsive disorder. (16996722)
2007
35
Association analysis between a VNTR intron 8 polymorphism of the dopamine transporter gene (SLC6A3) and obsessive- compulsive disorder in a Brazilian sample. (18094849)
2007
36
Rare plus common SERT variants in obsessive-compulsive disorder. (17453059)
2007
37
Selective cognitive deficits in obsessive-compulsive disorder compared to panic disorder with agoraphobia. (15667435)
2005
38
Obsessive-compulsive disorder and body dysmorphic disorder: a comparison of clinical features. (15276662)
2004
39
Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study. (15083261)
2004
40
Dopamine transporter density of basal ganglia assessed with [123I]IPT SPET in obsessive-compulsive disorder. (14513291)
2003
41
Obsessive compulsive disorder among idiopathic focal dystonia patients: an epidemiological and family study. (12208643)
2002
42
No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism. (10088048)
1999
43
Serotonergic function in social phobia: comparison to normal control and obsessive-compulsive disorder subjects. (9704868)
1998
44
Magnetic resonance brain imaging in women with obsessive-compulsive disorder and trichotillomania. (9255863)
1997
45
Obsessive compulsive symptoms in Gilles de la Tourette syndrome and obsessive compulsive disorder: differences by diagnosis and family history. (9259380)
1997
46
Genotype determining low catechol-O-methyltransferase activity as a risk factor for obsessive-compulsive disorder. (9114031)
1997
47
DRD2, DRD3 and 5HT2A receptor genes polymorphisms in obsessive-compulsive disorder. (9154247)
1996
48
Fenfluramine stimulation of prolactin in obsessive-compulsive disorder. (1603884)
1992
49
Response of obsessive-compulsive disorder and trichotillomania to serotonin reuptake blockers. (1728180)
1992
50
Prolactin and cortisol responses to MK-212, a serotonin agonist, in obsessive-compulsive disorder. (2203327)
1990

Variations for Obsessive-Compulsive Disorder

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Expression for genes affiliated with Obsessive-Compulsive Disorder

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Expression patterns in normal tissues for genes affiliated with Obsessive-Compulsive Disorder

Search GEO for disease gene expression data for Obsessive-Compulsive Disorder.

Pathways for genes affiliated with Obsessive-Compulsive Disorder

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Pathways related to Obsessive-Compulsive Disorder according to GeneCards/GeneDecks:

(show all 17)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8DRD1, DRD4
2
Show member pathways
Serotonin Transporter Activity37
9.7SLC6A4, MAOA
39.6MAOA, COMT
49.6MAOA, COMT
5
Show member pathways
9.6MAOA, COMT
69.6COMT, MAOA
7
Show member pathways
catecholamine biosynthesis37
9.1MAOA, COMT, TPH1
88.9SLC1A1, HTR1A, HTT, TPH1
9
Show member pathways
8.7HTR2A, HTR1B, HTR1A, DRD4, DRD1
10
Show member pathways
8.7MAOA, PDYN, DRD1, BDNF
11
Show member pathways
8.7MAOA, PDYN, DRD1, BDNF
12
Show member pathways
8.3HTR2A, HTR1B, HTR3A, HTR1A, BDNF
13
Show member pathways
8.1HTR2A, HTR1B, HTR1A, PDYN, DRD4, DRD1
14
Show member pathways
8.1HTR2A, HTR1B, HTR1A, PDYN, DRD4, DRD1
157.4TPH1, HTR2A, HTR3A, HTR1A, MAOA, BDNF
167.4TPH1, HTR2A, HTR1B, HTR3A, HTR1A, MAOA
17
Show member pathways
6.0SLC1A1, TPH1, HTR2A, HTR1B, SLC6A4, DRD1

Compounds for genes affiliated with Obsessive-Compulsive Disorder

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Compounds related to Obsessive-Compulsive Disorder according to GeneCards/GeneDecks:

(show top 50)    (show all 277)
idCompoundScoreTop Affiliating Genes
1mhpg449.0SLC6A4, DRD4, COMT, MAOA, BDNF
2methylphenidate44 50 1110.8DRD4, DRD1, SLC6A4, COMT, MAOA
3ropinirole44 119.8DRD1, DRD4, COMT, HTR1A, HTR1B, HTR2A
4mcpp448.7HTR1B, HTR1A, HTR2A, SLC6A4, HTR3A
5pergolide44 28 1110.7HTR1B, DRD1, DRD4, COMT, HTR1A, HTR2A
6lisuride44 28 1110.7HTR1B, HTR1A, DRD4, DRD1, HTR2A
7cabergoline44 28 1110.7DRD1, DRD4, COMT, HTR1A, HTR1B, HTR2A
8pindolol44 28 1110.7HTR3A, SLC6A4, HTR1A, HTR1B, HTR2A
9apomorphine28 44 1110.7HTR1A, HTR2A, HTR1B, DRD4, COMT, DRD1
10bromocriptine44 28 1110.6HTR2A, HTR1B, HTR1A, COMT, DRD4, DRD1
11homovanillic acid44 249.5BDNF, MAOA, COMT, TPH1, SLC6A4
12nefazodone44 50 1110.5HTR1A, HTR3A, HTR1B, SLC6A4, HTR2A
13pramipexole44 28 50 1111.5DRD1, DRD4, COMT, HTR1A, HTR1B, BDNF
14spiperone44 289.5DRD1, DRD4, HTR1A, HTR3A, HTR2A
155-hydroxytryptophan448.4HTR1A, HTR2A, TPH1, HTR3A, SLC6A4
16(tfmpp)448.3HTR2A, HTR3A, HTR1A, HTR1B
17fenfluramine44 28 1110.3TPH1, SLC6A4, HTR1A, HTR3A, HTR1B, HTR2A
18aripiprazole28 44 50 24 1112.3HTR2A, HTR1B, HTR3A, DRD4, DRD1, HTR1A
19cocaine44 119.3SLC6A4, DRD4, DRD1, BDNF, COMT, HTR1B
20ziprasidone28 50 44 1111.2HTR1A, HTR1B, HTR3A, DRD4, DRD1, HTR2A
21Serotonin248.2HTR1B, SLC6A4, MAOA, HTR3A, HTR1A, HTR2A
22methysergide44 28 1110.2MAOA, HTR1A, HTR3A, HTR1B, HTR2A
23chlorpromazine28 44 50 1111.2DRD4, HTR2A, HTR3A, HTR1A, DRD1, BDNF
24clomipramine44 50 1110.2SLC6A4, HTR1B, HTR3A, HTR1A, MAOA, HTR2A
25mianserin44 28 1110.2HTR1A, HTR3A, HTR2A, SLC6A4, MAOA
266-hydroxydopamine448.2MAOA, PDYN, DRD4, DRD1, BDNF, COMT
27venlafaxine44 50 24 1111.2HTR2A, BDNF, SLC6A4, COMT, HTR1A, HTR3A
28iloperidone50 44 28 1111.2DRD4, HTR1A, HTR3A, DRD1, HTR2A
29ketanserin44 289.1SLC6A4, BDNF, DRD1, HTR3A, HTR1B, HTR2A
30amphetamine44 50 1110.1DRD4, TPH1, PDYN, SLC6A4, DRD1, MAOA
31haloperidol44 50 28 2 1112.0DRD4, HTR1A, DRD1, BDNF, HTR3A, HTR2A
32imipramine44 28 50 24 1111.9SLC6A4, BDNF, HTR2A, HTR3A, HTR1A, MAOA
33catecholamine447.9MAOA, COMT, PDYN, DRD4, DRD1, BDNF
34citalopram44 50 24 1110.8TPH1, HTR2A, HTR3A, HTR1A, MAOA, BDNF
35quetiapine44 50 28 24 1111.8SLC6A4, HTR1B, HTR2A, HTR3A, HTR1A, BDNF
36maoa447.7COMT, HTR1A, HTR1B, HTR2A, TPH1, MAOA
37methamphetamine44 50 119.7TPH1, COMT, MAOA, PDYN, DRD4, DRD1
38fluoxetine44 50 28 1110.6HTR2A, TPH1, HTR1B, HTR3A, HTR1A, SLC6A4
39fluvoxamine44 50 119.5SLC6A4, BDNF, MAOA, COMT, HTR1A, HTR3A
40olanzapine44 50 28 24 1111.5SLC6A4, BDNF, DRD1, DRD4, COMT, HTR1A
41risperidone44 50 28 61 24 1112.5DRD4, COMT, HTR1A, HTR3A, HTR1B, HTR2A
42clozapine44 28 50 1110.5SLC6A4, BDNF, DRD1, DRD4, HTR2A, HTR1B
43nmda44 288.3SLC6A4, HTR1A, HTT, SLC1A1, BDNF, DRD1
445-hydroxytryptamine447.1TPH1, HTR2A, HTR1B, HTR3A, HTR1A, COMT
45levodopa44 118.1HTR1A, COMT, MAOA, PDYN, DRD4, DRD1
46glutamate447.0MAOA, PDYN, DRD4, BDNF, DRD1, COMT
47gaba446.9BDNF, SLC6A4, SLC1A1, DRD1, DRD4, TPH1
48paroxetine44 50 28 119.9HTR3A, HTR2A, TPH1, HTR1A, COMT, MAOA
49norepinephrine44 24 118.1HTR3A, HTR1A, COMT, MAOA, PDYN, DRD4
50dopamine44 28 24 118.6TPH1, HTR2A, DRD4, DRD1, BDNF, SLC6A4

GO Terms for genes affiliated with Obsessive-Compulsive Disorder

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Cellular components related to Obsessive-Compulsive Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1axonGO:0304249.2HTT, HTR3A, HTR2A
2integral component of plasma membraneGO:0058876.9SLC1A1, SGCE, HTR2A, HTR1B, HTR3A, HTR1A
3plasma membraneGO:0058866.0HTR2A, HTR1B, HTR3A, HTR1A, COMT, PDYN

Biological processes related to Obsessive-Compulsive Disorder according to GeneCards/GeneDecks:

(show all 30)
idNameGO IDScoreTop Affiliating Genes
1regulation of dopamine secretionGO:01405910.2HTR2A, HTR1B
2L-glutamate importGO:05193810.2SLC1A1, HTT
3negative regulation of synaptic transmission, glutamatergicGO:05196710.2HTR1B, HTR2A
4dopamine receptor signaling pathwayGO:00721210.2HTT, DRD4
5negative regulation of cAMP biosynthetic processGO:03081810.1HTR1B, DRD4
6regulation of hormone secretionGO:04688310.1HTR1A, HTR2A
7social behaviorGO:03517610.0SLC6A4, DRD4, HTT
8adenylate cyclase-inhibiting serotonin receptor signaling pathwayGO:00719810.0HTR1B, HTR1A
9dopamine metabolic processGO:04241710.0DRD1, DRD4
10striatum developmentGO:02175610.0HTT, DRD1
11synaptic transmission, dopaminergicGO:0019639.9DRD4, DRD1
12memoryGO:0076139.9SLC6A4, DRD1, HTR2A
13dopamine catabolic processGO:0424209.9COMT, MAOA
14behavioral response to cocaineGO:0481489.9HTR2A, DRD4, DRD1
15bone remodelingGO:0468499.9TPH1, HTR1B
16neurotransmitter catabolic processGO:0421359.9MAOA, COMT
17grooming behaviorGO:0076259.9HTT, DRD1
18circadian rhythmGO:0076239.8TPH1, DRD4, SLC6A4
19temperature homeostasisGO:0016599.8DRD1, HTR2A
20protein import into nucleusGO:0066069.8DRD1, HTT
21vasoconstrictionGO:0423109.8SLC6A4, HTR1A, HTR1B
22regulation of behaviorGO:0507959.8HTR1A, HTR1B, HTR2A
23neurotransmitter biosynthetic processGO:0421369.7COMT, MAOA
24regulation of dopamine metabolic processGO:0420539.6HTR1A, DRD4, DRD1
25response to drugGO:0424939.5HTR2A, COMT, DRD1, SLC6A4
26response to amphetamineGO:0019759.5DRD1, DRD4
27behavioral fear responseGO:0016629.4HTR1A, DRD4, DRD1, BDNF
28response to cocaineGO:0422209.3HTR1B, HTR3A
29serotonin receptor signaling pathwayGO:0072109.3HTR1A, HTR3A, HTR2A
30synaptic transmissionGO:0072688.6SLC1A1, MAOA, COMT, HTR3A, HTR2A

Molecular functions related to Obsessive-Compulsive Disorder according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1dopamine bindingGO:0352409.8DRD1, DRD4
2dopamine neurotransmitter receptor activityGO:0049529.7DRD4, DRD1
3drug bindingGO:0081449.4DRD4, HTR1B, HTR2A
4serotonin bindingGO:0513789.1HTR3A, HTR1B, HTR2A
5serotonin receptor activityGO:0049938.7HTR1A, HTR3A, HTR1B, HTR2A

Products for genes affiliated with Obsessive-Compulsive Disorder

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3CDC
13ExPASy
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23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
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51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
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