Aliases & Classifications for Occipital Neuralgia

MalaCards integrated aliases for Occipital Neuralgia:

Name: Occipital Neuralgia 50
Cervico-Occipital Neuralgia 69

External Ids:

UMLS 69 C0007863

Summaries for Occipital Neuralgia

NINDS : 50 Occipital neuralgia is a distinct type of headache characterized by piercing, throbbing, or electric-shock-like chronic pain in the upper neck, back of the head, and behind the ears, usually on one side of the head.  Typically, the pain of occipital neuralgia begins in the neck and then spreads upwards.  Some individuals will also experience pain in the scalp, forehead, and behind the eyes.  Their scalp may also be tender to the touch, and their eyes especially sensitive to light.  The location of pain is related to the areas supplied by the greater and lesser occipital nerves, which run from the area where the spinal column meets the neck, up to the scalp at the back of the head.  The pain is caused by irritation or injury to the nerves, which can be the result of trauma to the back of the head, pinching of the nerves by overly tight neck muscles, compression of the nerve as it leaves the spine due to osteoarthritis, or tumors or other types of lesions in the neck.  Localized inflammation or infection, gout, diabetes, blood vessel inflammation (vasculitis), and frequent lengthy periods of keeping the head in a downward and forward position are also associated with occipital neuralgia.  In many cases, however, no cause can be found.  A positive response (relief from pain) after an anesthetic nerve block will confirm the diagnosis.

MalaCards based summary : Occipital Neuralgia, also known as cervico-occipital neuralgia, is related to cervicitis and headache, and has symptoms including recurrent paroxysmal headache, neuralgia and headache. The drugs Bupivacaine and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include eye, dorsal root ganglion and b cells.

Wikipedia : 72 Occipital neuralgia is a medical condition characterized by chronic pain in the upper neck, back of the... more...

Related Diseases for Occipital Neuralgia

Diseases related to Occipital Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 33)
# Related Disease Score Top Affiliating Genes
1 cervicitis 10.4
2 headache 10.3
3 episodic pain syndrome, familial, 1 10.2
4 migraine with or without aura 1 10.2
5 myelitis 10.2
6 herpes zoster 10.0
7 vasculitis 10.0
8 chordoma 9.9
9 arthropathy 9.9
10 arteriovenous fistula 9.9
11 neuromyelitis optica 9.8
12 osteoarthritis 9.8
13 whiplash 9.8
14 lipomatosis, multiple 9.8
15 lymphoma 9.8
16 chondromyxoid fibroma 9.8
17 acoustic neuroma 9.8
18 neurofibromatosis, type iv, of riccardi 9.8
19 melanoma 9.8
20 temporal arteritis 9.8
21 leiomyosarcoma 9.8
22 trigeminal neuralgia 9.8
23 neuroma 9.8
24 paine syndrome 9.8
25 osteoarthritis with mild chondrodysplasia 9.8
26 meningioma, familial 9.8
27 foramen magnum meningioma 9.8
28 gastric cancer 9.8
29 idiopathic hypertrophic pachymeningitis 9.8
30 b-cell lymphomas 9.8
31 neuromyelitis optica spectrum disorder 9.8
32 diffuse large b-cell lymphoma 9.8
33 neurosyphilis 9.8

Graphical network of the top 20 diseases related to Occipital Neuralgia:



Diseases related to Occipital Neuralgia

Symptoms & Phenotypes for Occipital Neuralgia

UMLS symptoms related to Occipital Neuralgia:


recurrent paroxysmal headache, neuralgia, headache

Drugs & Therapeutics for Occipital Neuralgia

Drugs for Occipital Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 54)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4,Phase 1 38396-39-3, 2180-92-9 2474
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4 Central Nervous System Depressants Phase 4
5 Anesthetics Phase 4,Phase 1
6 Anesthetics, Local Phase 4
7 Peripheral Nervous System Agents Phase 4
8 triamcinolone acetonide Phase 4
9 Dexamethasone acetate Phase 4 1177-87-3
10 glucocorticoids Phase 4
11
protease inhibitors Phase 4
12 Gastrointestinal Agents Phase 4
13 Triamcinolone diacetate Phase 4
14 Triamcinolone hexacetonide Phase 4
15 HIV Protease Inhibitors Phase 4
16 Hormone Antagonists Phase 4
17 Hormones Phase 4
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
19 Antiemetics Phase 4
20 Immunosuppressive Agents Phase 4
21 Anti-Inflammatory Agents Phase 4
22 Antineoplastic Agents, Hormonal Phase 4
23 BB 1101 Phase 4
24 Autonomic Agents Phase 4
25
Betamethasone Approved, Vet_approved Phase 1 378-44-9 9782
26
Lidocaine Approved, Vet_approved Phase 1 137-58-6 3676
27
Menthol Approved Phase 1 2216-51-5 16666
28
Vitamin A Approved, Nutraceutical, Vet_approved Phase 1 68-26-8, 11103-57-4 445354
29 Betamethasone Valerate Phase 1 2152-44-5
30 Retinol palmitate Phase 1
31 Betamethasone benzoate Phase 1
32 Betamethasone sodium phosphate Phase 1
33 Betamethasone-17,21-dipropionate Phase 1
34 retinol Nutraceutical Phase 1
35
Epinephrine Approved, Vet_approved 51-43-4 5816
36
Prednisolone Approved, Vet_approved 50-24-8 5755
37
Methylprednisolone Approved, Vet_approved 83-43-2 6741
38 Racepinephrine Approved 329-65-7
39 Prednisolone acetate
40 Respiratory System Agents
41 Methylprednisolone acetate
42 Methylprednisolone Hemisuccinate
43 Adrenergic Agents
44 Adrenergic Agonists
45 Adrenergic alpha-Agonists
46 Mydriatics
47 Adrenergic beta-Agonists
48 Neurotransmitter Agents
49 Vasoconstrictor Agents
50 Anti-Asthmatic Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks Recruiting NCT02655523 Phase 4 Triamcinolone;Dexamethasone;Normal Saline;Bupivacaine
2 Greater Occipital Nerve Injection Study Completed NCT01988363 Phase 1
3 Study Evaluating the Treatment of Occipital Neuralgia Completed NCT01753765
4 Pulsed Radiofrequency vs. Steroid Injections for Occipital Neuralgia Completed NCT01670825 Corticosteroid injection;Local anethestic injection
5 Ultrasound Greater Occipital Nerve Block at C2 Level Compared to Landmark-based Greater Occipital Nerve Block Recruiting NCT03478735 Not Applicable
6 Two US-guided Techniques for Greater Occipital Nerve Blocks Active, not recruiting NCT02031822
7 Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management Not yet recruiting NCT03253523
8 Evaluation of Occipital Nerve Stimulation in Intractable Occipital Neuralgias Not yet recruiting NCT03475797 Not Applicable

Search NIH Clinical Center for Occipital Neuralgia

Genetic Tests for Occipital Neuralgia

Anatomical Context for Occipital Neuralgia

MalaCards organs/tissues related to Occipital Neuralgia:

38
Eye, Dorsal Root Ganglion, B Cells, Medulla Oblongata

Publications for Occipital Neuralgia

Articles related to Occipital Neuralgia:

(show top 50) (show all 157)
# Title Authors Year
1
Practical considerations of linear accelerator-based frameless extracranial radiosurgery for treatment of occipital neuralgia for nonsurgical candidates. ( 28517492 )
2017
2
Unilateral occipital nerve stimulation for bilateral occipital neuralgia: a case report and literature review. ( 28176938 )
2017
3
Acute-Onset Severe Occipital Neuralgia Associated With High Cervical Lesion in Patients With Neuromyelitis Optica Spectrum Disorder. ( 28699327 )
2017
4
Hemifacial Pain and Hemisensory Disturbance Referred from Occipital Neuralgia Caused by Pathological Vascular Contact of the Greater Occipital Nerve. ( 28331643 )
2017
5
An anatomical study of the transversus nuchae muscle: Application to better understanding occipital neuralgia. ( 27685778 )
2017
6
Occipital Nerve Stimulation for the Treatment of Refractory Occipital Neuralgia: A Case Series. ( 28634063 )
2017
7
Modified posterior C1 lateral mass screw insertion for type II odontoid process fractures using intraoperative CT-based spinal navigation to minimize postoperative occipital neuralgia. ( 28826707 )
2017
8
Greater Occipital Nerve Cryoneurolysis in the management of intractable Occipital Neuralgia. ( 29273528 )
2017
9
Postoperative occipital neuralgia in posterior upper cervical spine surgery: a systematic review. ( 29116423 )
2017
10
Occipital Neuralgia in Chiari I Malformation: Two Different Events or Two Different Faces of the Same Event? ( 29392103 )
2017
11
Diagnosis of occipital neuralgia due to upper cervical chordoma. ( 28757915 )
2017
12
Cervical myelitis presenting as occipital neuralgia. ( 29124999 )
2017
13
The treatment of occipital neuralgia: Review of 111 cases. ( 27546882 )
2016
14
Cervical Myelitis Presenting as Occipital Neuralgia. ( 28025377 )
2016
15
Cervical Myelitis Presenting as Occipital Neuralgia. ( 27257286 )
2016
16
Neuralgias of the Head: Occipital Neuralgia. ( 27051229 )
2016
17
Occipital Neuralgia Diagnosis and Treatment: The Role of Ultrasound. ( 26997206 )
2016
18
A case of occipital neuralgia in a vemurafenib-treated melanoma patient. ( 27653311 )
2016
19
Intramuscular Lipoma-Induced Occipital Neuralgia on the Lesser Occipital Nerve. ( 27152569 )
2016
20
Distraction Arthrodesis of the C1-C2 Facet Joint with Preservation of the C2 Root for the Management of Intractable Occipital Neuralgia Caused by C2 Root Compression. ( 26731710 )
2015
21
Occipital neuralgia as a sequela of sports concussion: a case series and review of the literature. ( 25574876 )
2015
22
Occipital neuralgia secondary to unilateral atlantoaxial osteoarthritis: Case report and review of the literature. ( 26759731 )
2015
23
A simplified CT-guided approach for greater occipital nerve infiltration in the management of occipital neuralgia. ( 25680724 )
2015
24
Long-term outcomes of intradural cervical dorsal root rhizotomy for refractory occipital neuralgia. ( 26684782 )
2015
25
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197206 )
2015
26
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26186585 )
2015
27
Cryoablation for the treatment of occipital neuralgia. ( 26000683 )
2015
28
Occipital neuralgia after scalp biopsy and curettage. ( 26265207 )
2015
29
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness. ( 26447705 )
2015
30
Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline. ( 26125672 )
2015
31
Occipital neuralgia heralding occipital condyle syndrome revealing vesical leiomyosarcoma skull base metastasis. ( 26411377 )
2015
32
Idiopathic hypertrophic pachymeningitis presenting with occipital neuralgia. ( 25834565 )
2015
33
Improvement in clinical outcomes after dry needling in a patient with occipital neuralgia. ( 26136602 )
2015
34
Schwannoma of the greater occipital nerve: An uncommon cause of occipital neuralgia. ( 26752925 )
2015
35
Nurse-led treatment for occipital neuralgia. ( 26455130 )
2015
36
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197205 )
2015
37
Peripheral Nerve Stimulation for Occipital Neuralgia. ( 26365981 )
2015
38
Occipital neuralgia after hair transplantation and its treatment. ( 25688308 )
2015
39
The intramuscular course of the greater occipital nerve: novel findings with potential implications for operative interventions and occipital neuralgia. ( 25422783 )
2014
40
Atlantoaxial Chordoma in Two Patients with Occipital Neuralgia and Cervicalgia. ( 26064862 )
2014
41
Occipital neuralgia: Anatomic considerations. ( 25244129 )
2014
42
Cooled radiofrequency ablation for bilateral greater occipital neuralgia. ( 24716017 )
2014
43
Pulsed radiofrequency for occipital neuralgia. ( 25415786 )
2014
44
Greater occipital nerve excision for occipital neuralgia refractory to nerve decompression. ( 24322636 )
2014
45
Ultrasound guided greater occipital nerve blocks for post-traumatic occipital neuralgia. ( 24902462 )
2014
46
Successful treatment of occipital neuralgia with implantable peripheral nerve stimulation in a pacemaker-dependent patient. ( 24688344 )
2014
47
Nummular headache in a patient with ipsilateral occipital neuralgia--a case report. ( 24821641 )
2014
48
Cervical myelitis mimicking intractable occipital neuralgia. ( 24465268 )
2014
49
Occipital neuralgia. ( 24737457 )
2014
50
Response of Cervicogenic Headaches and Occipital Neuralgia to Radiofrequency Ablation of the C2 Dorsal Root Ganglion and/or Third Occipital Nerve. ( 24433241 )
2014

Variations for Occipital Neuralgia

Expression for Occipital Neuralgia

Search GEO for disease gene expression data for Occipital Neuralgia.

Pathways for Occipital Neuralgia

GO Terms for Occipital Neuralgia

Sources for Occipital Neuralgia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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