Aliases & Classifications for Occipital Neuralgia

MalaCards integrated aliases for Occipital Neuralgia:

Name: Occipital Neuralgia 51
Cervico-Occipital Neuralgia 69

Summaries for Occipital Neuralgia

NINDS : 51 Occipital neuralgia is a distinct type of headache characterized by piercing, throbbing, or electric-shock-like chronic pain in the upper neck, back of the head, and behind the ears, usually on one side of the head.  Typically, the pain of occipital neuralgia begins in the neck and then spreads upwards.  Some individuals will also experience pain in the scalp, forehead, and behind the eyes.  Their scalp may also be tender to the touch, and their eyes especially sensitive to light.  The location of pain is related to the areas supplied by the greater and lesser occipital nerves, which run from the area where the spinal column meets the neck, up to the scalp at the back of the head.  The pain is caused by irritation or injury to the nerves, which can be the result of trauma to the back of the head, pinching of the nerves by overly tight neck muscles, compression of the nerve as it leaves the spine due to osteoarthritis, or tumors or other types of lesions in the neck.  Localized inflammation or infection, gout, diabetes, blood vessel inflammation (vasculitis), and frequent lengthy periods of keeping the head in a downward and forward position are also associated with occipital neuralgia.  In many cases, however, no cause can be found.  A positive response (relief from pain) after an anesthetic nerve block will confirm the diagnosis.

MalaCards based summary : Occipital Neuralgia, also known as cervico-occipital neuralgia, is related to headache and cervicitis, and has symptoms including headache, neuralgia and recurrent paroxysmal headache. The drugs Bupivacaine and Dexamethasone have been mentioned in the context of this disorder. Affiliated tissues include eye, dorsal root ganglion and b cells.

Wikipedia : 72 Occipital neuralgia is a medical condition characterized by chronic pain in the upper neck, back of the... more...

Related Diseases for Occipital Neuralgia

Diseases related to Occipital Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 27)
id Related Disease Score Top Affiliating Genes
1 headache 10.3
2 cervicitis 10.2
3 myelitis 10.0
4 herpes zoster 9.9
5 vasculitis 9.9
6 chordoma 9.8
7 arteriovenous fistula 9.8
8 arthropathy 9.8
9 neurofibromatosis, type 1 9.7
10 temporal arteritis 9.7
11 trigeminal neuralgia 9.7
12 b-cell lymphomas 9.7
13 diffuse large b-cell lymphoma 9.7
14 neuromyelitis optica 9.7
15 osteoarthritis 9.7
16 fibroma 9.7
17 lymphoma 9.7
18 acoustic neuroma 9.7
19 melanoma 9.7
20 leiomyosarcoma 9.7
21 neuroma 9.7
22 foramen magnum meningioma 9.7
23 idiopathic hypertrophic pachymeningitis 9.7
24 neuromyelitis optica spectrum disorder 9.7
25 neurosyphilis 9.7
26 whiplash 9.7
27 chondromyxoid fibroma 9.7

Graphical network of the top 20 diseases related to Occipital Neuralgia:



Diseases related to Occipital Neuralgia

Symptoms & Phenotypes for Occipital Neuralgia

UMLS symptoms related to Occipital Neuralgia:


headache, neuralgia, recurrent paroxysmal headache

Drugs & Therapeutics for Occipital Neuralgia

Drugs for Occipital Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 70)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
2
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 1,Phase 2 50-02-2 5743
3
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
4 Anesthetics Phase 4,Phase 3,Phase 1,Phase 2
5 Anesthetics, Local Phase 4,Phase 3,Phase 1,Phase 2
6 Central Nervous System Depressants Phase 4,Phase 3,Phase 1,Phase 2
7 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 1,Phase 2
8 Antiemetics Phase 4,Phase 1,Phase 2
9 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 1,Phase 2
10 Antineoplastic Agents, Hormonal Phase 4,Phase 1,Phase 2
11 Autonomic Agents Phase 4,Phase 1,Phase 2
12 BB 1101 Phase 4,Phase 3,Phase 1,Phase 2
13 Dexamethasone acetate Phase 4,Phase 3,Phase 1,Phase 2 1177-87-3
14 Gastrointestinal Agents Phase 4,Phase 1,Phase 2
15 glucocorticoids Phase 4,Phase 1,Phase 2
16 HIV Protease Inhibitors Phase 4,Phase 1,Phase 2
17 Hormone Antagonists Phase 4,Phase 1,Phase 2
18 Hormones Phase 4,Phase 1,Phase 2
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 1,Phase 2
20 Immunosuppressive Agents Phase 4
21
protease inhibitors Phase 4,Phase 1,Phase 2
22 triamcinolone acetonide Phase 4
23 Triamcinolone diacetate Phase 4
24 Triamcinolone hexacetonide Phase 4
25
Lidocaine Approved, Vet_approved Phase 3,Phase 1,Phase 2 137-58-6 3676
26 Anti-Arrhythmia Agents Phase 3,Phase 1,Phase 2
27 Diuretics, Potassium Sparing Phase 3,Phase 1,Phase 2
28 Sodium Channel Blockers Phase 3,Phase 1,Phase 2
29
Alprazolam Approved, Illicit, Investigational Phase 1, Phase 2 28981-97-7 2118
30
Prilocaine Approved Phase 1, Phase 2 721-50-6 4906
31
Folic Acid Approved, Nutraceutical, Vet_approved Phase 1, Phase 2 59-30-3 6037
32
Thiamine Approved, Nutraceutical, Vet_approved Phase 1, Phase 2 59-43-8 1130
33 Anti-Anxiety Agents Phase 1, Phase 2
34 Dexamethasone 21-phosphate Phase 1, Phase 2
35 Micronutrients Phase 1, Phase 2
36 Trace Elements Phase 1, Phase 2
37 Vitamin B Complex Phase 1, Phase 2
38 Vitamins Phase 1, Phase 2
39 Folate Nutraceutical Phase 1, Phase 2
40 Thiamin Nutraceutical Phase 1, Phase 2
41 Vitamin B9 Nutraceutical Phase 1, Phase 2
42
Betamethasone Approved, Vet_approved Phase 1 378-44-9 9782
43
Menthol Approved Phase 1 2216-51-5 16666
44
Vitamin A Approved, Nutraceutical, Vet_approved Phase 1 11103-57-4, 68-26-8 445354
45 Betamethasone benzoate Phase 1
46 Betamethasone sodium phosphate Phase 1
47 Betamethasone Valerate Phase 1 2152-44-5
48 Betamethasone-17,21-dipropionate Phase 1
49 Retinol palmitate Phase 1
50 retinol Nutraceutical Phase 1

Interventional clinical trials:


id Name Status NCT ID Phase Drugs
1 A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks Recruiting NCT02655523 Phase 4 Triamcinolone;Dexamethasone;Normal Saline;Bupivacaine
2 A Prospective Controlled Treatment Trial for Post-Traumatic Headaches Recruiting NCT03007420 Phase 3 Occipital Nerve Block (ONB) using lidocaine and dexamethosone;Cervical Medial Branch Block (CMBB) using lidocaine and dexamethosone
3 Treatment of Chronic Migraine Headaches. Recruiting NCT03220113 Phase 1, Phase 2
4 Greater Occipital Nerve Injection Study Completed NCT01988363 Phase 1
5 Study Evaluating the Treatment of Occipital Neuralgia Completed NCT01753765
6 Pulsed Radiofrequency vs. Steroid Injections for Occipital Neuralgia Completed NCT01670825 Corticosteroid injection;Local anethestic injection
7 Two US-guided Techniques for Greater Occipital Nerve Blocks Recruiting NCT02031822
8 Post-traumatic Occipital Neuralgia - Surgical Versus Medical Management Not yet recruiting NCT03253523

Search NIH Clinical Center for Occipital Neuralgia

Genetic Tests for Occipital Neuralgia

Anatomical Context for Occipital Neuralgia

MalaCards organs/tissues related to Occipital Neuralgia:

39
Eye, Dorsal Root Ganglion, B Cells, Medulla Oblongata

Publications for Occipital Neuralgia

Articles related to Occipital Neuralgia:

(show top 50) (show all 153)
id Title Authors Year
1
Hemifacial Pain and Hemisensory Disturbance Referred from Occipital Neuralgia Caused by Pathological Vascular Contact of the Greater Occipital Nerve. ( 28331643 )
2017
2
An anatomical study of the transversus nuchae muscle: Application to better understanding occipital neuralgia. ( 27685778 )
2017
3
Acute-Onset Severe Occipital Neuralgia Associated With High Cervical Lesion in Patients With Neuromyelitis Optica Spectrum Disorder. ( 28699327 )
2017
4
Diagnosis of occipital neuralgia due to upper cervical chordoma. ( 28757915 )
2017
5
Modified posterior C1 lateral mass screw insertion for type II odontoid process fractures using intraoperative CT-based spinal navigation to minimize postoperative occipital neuralgia. ( 28826707 )
2017
6
Occipital Nerve Stimulation for the Treatment of Refractory Occipital Neuralgia: A Case Series. ( 28634063 )
2017
7
Unilateral occipital nerve stimulation for bilateral occipital neuralgia: a case report and literature review. ( 28176938 )
2017
8
Practical considerations of linear accelerator-based frameless extracranial radiosurgery for treatment of occipital neuralgia for nonsurgical candidates. ( 28517492 )
2017
9
Occipital Neuralgia Diagnosis and Treatment: The Role of Ultrasound. ( 26997206 )
2016
10
Intramuscular Lipoma-Induced Occipital Neuralgia on the Lesser Occipital Nerve. ( 27152569 )
2016
11
Cervical Myelitis Presenting as Occipital Neuralgia. ( 27257286 )
2016
12
A case of occipital neuralgia in a vemurafenib-treated melanoma patient. ( 27653311 )
2016
13
Neuralgias of the Head: Occipital Neuralgia. ( 27051229 )
2016
14
The treatment of occipital neuralgia: Review of 111 cases. ( 27546882 )
2016
15
Cervical Myelitis Presenting as Occipital Neuralgia. ( 28025377 )
2016
16
Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline. ( 26125672 )
2015
17
Peripheral Nerve Stimulation for Occipital Neuralgia. ( 26365981 )
2015
18
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197206 )
2015
19
A simplified CT-guided approach for greater occipital nerve infiltration in the management of occipital neuralgia. ( 25680724 )
2015
20
Distraction Arthrodesis of the C1-C2 Facet Joint with Preservation of the C2 Root for the Management of Intractable Occipital Neuralgia Caused by C2 Root Compression. ( 26731710 )
2015
21
Occipital neuralgia secondary to unilateral atlantoaxial osteoarthritis: Case report and review of the literature. ( 26759731 )
2015
22
Idiopathic hypertrophic pachymeningitis presenting with occipital neuralgia. ( 25834565 )
2015
23
Occipital neuralgia heralding occipital condyle syndrome revealing vesical leiomyosarcoma skull base metastasis. ( 26411377 )
2015
24
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26186585 )
2015
25
Occipital neuralgia as a sequela of sports concussion: a case series and review of the literature. ( 25574876 )
2015
26
Long-term outcomes of intradural cervical dorsal root rhizotomy for refractory occipital neuralgia. ( 26684782 )
2015
27
Schwannoma of the greater occipital nerve: An uncommon cause of occipital neuralgia. ( 26752925 )
2015
28
Occipital neuralgia after scalp biopsy and curettage. ( 26265207 )
2015
29
Improvement in clinical outcomes after dry needling in a patient with occipital neuralgia. ( 26136602 )
2015
30
Cryoablation for the treatment of occipital neuralgia. ( 26000683 )
2015
31
Occipital neuralgia after hair transplantation and its treatment. ( 25688308 )
2015
32
Nurse-led treatment for occipital neuralgia. ( 26455130 )
2015
33
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness. ( 26447705 )
2015
34
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197205 )
2015
35
Long-term outcome and prognostic factors after C2 ganglion decompression in 68 consecutive patients with intractable occipital neuralgia. ( 25352089 )
2014
36
Occipital neuralgia: Anatomic considerations. ( 25244129 )
2014
37
Successful treatment of occipital neuralgia with implantable peripheral nerve stimulation in a pacemaker-dependent patient. ( 24688344 )
2014
38
Cervical myelitis mimicking intractable occipital neuralgia. ( 24465268 )
2014
39
The intramuscular course of the greater occipital nerve: novel findings with potential implications for operative interventions and occipital neuralgia. ( 25422783 )
2014
40
C2 nerve root on magnetic resonance imaging of occipital neuralgia. ( 24732835 )
2014
41
Response of Cervicogenic Headaches and Occipital Neuralgia to Radiofrequency Ablation of the C2 Dorsal Root Ganglion and/or Third Occipital Nerve. ( 24433241 )
2014
42
Cooled radiofrequency ablation for bilateral greater occipital neuralgia. ( 24716017 )
2014
43
Greater occipital nerve excision for occipital neuralgia refractory to nerve decompression. ( 24322636 )
2014
44
Ultrasound guided greater occipital nerve blocks for post-traumatic occipital neuralgia. ( 24902462 )
2014
45
Occipital neuralgia. ( 24737457 )
2014
46
Nummular headache in a patient with ipsilateral occipital neuralgia--a case report. ( 24821641 )
2014
47
Atlantoaxial Chordoma in Two Patients with Occipital Neuralgia and Cervicalgia. ( 26064862 )
2014
48
Pulsed radiofrequency for occipital neuralgia. ( 25415786 )
2014
49
Modified C1 lateral mass screw insertion using a high entry point to avoid postoperative occipital neuralgia. ( 23117140 )
2013
50
Postoperative occipital neuralgia with and without C2 nerve root transection during atlantoaxial screw fixation: a post-hoc comparative outcome study of prospectively collected data. ( 23711959 )
2013

Variations for Occipital Neuralgia

Expression for Occipital Neuralgia

Search GEO for disease gene expression data for Occipital Neuralgia.

Pathways for Occipital Neuralgia

GO Terms for Occipital Neuralgia

Sources for Occipital Neuralgia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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