Aliases & Classifications for Occipital Neuralgia

Aliases & Descriptions for Occipital Neuralgia:

Name: Occipital Neuralgia 51
Cervico-Occipital Neuralgia 69

Summaries for Occipital Neuralgia

NINDS : 51 Occipital neuralgia is a distinct type of headache characterized by piercing, throbbing, or electric-shock-like chronic pain in the upper neck, back of the head, and behind the ears, usually on one side of the head.  Typically, the pain of occipital neuralgia begins in the neck and then spreads upwards.  Some individuals will also experience pain in the scalp, forehead, and behind the eyes.  Their scalp may also be tender to the touch, and their eyes especially sensitive to light.  The location of pain is related to the areas supplied by the greater and lesser occipital nerves, which run from the area where the spinal column meets the neck, up to the scalp at the back of the head.  The pain is caused by irritation or injury to the nerves, which can be the result of trauma to the back of the head, pinching of the nerves by overly tight neck muscles, compression of the nerve as it leaves the spine due to osteoarthritis, or tumors or other types of lesions in the neck.  Localized inflammation or infection, gout, diabetes, blood vessel inflammation (vasculitis), and frequent lengthy periods of keeping the head in a downward and forward position are also associated with occipital neuralgia.  In many cases, however, no cause can be found.  A positive response (relief from pain) after an anesthetic nerve block will confirm the diagnosis.

MalaCards based summary : Occipital Neuralgia, also known as cervico-occipital neuralgia, is related to headache and cervicitis, and has symptoms including headache, neuralgia and recurrent paroxysmal headache. The drugs Lidocaine and Bupivacaine have been mentioned in the context of this disorder. Affiliated tissues include eye, dorsal root ganglion and b cells.

Wikipedia : 71 Occipital neuralgia, also known as C2 neuralgia or, rarely, Arnold\'s neuralgia, is a medical condition... more...

Related Diseases for Occipital Neuralgia

Diseases related to Occipital Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 28)
id Related Disease Score Top Affiliating Genes
1 headache 10.3
2 cervicitis 10.2
3 myelitis 10.0
4 herpes zoster 9.9
5 vasculitis 9.9
6 arteriovenous fistula 9.8
7 arthropathy 9.8
8 trigeminal neuralgia 9.7
9 b-cell lymphomas 9.7
10 neurofibromatosis 9.7
11 diffuse large b-cell lymphoma 9.7
12 idiopathic hypertrophic pachymeningitis 9.7
13 gastric cancer 9.7
14 neurosyphilis 9.7
15 osteoarthritis 9.7
16 fibroma 9.7
17 whiplash 9.7
18 lymphoma 9.7
19 chondromyxoid fibroma 9.7
20 acoustic neuroma 9.7
21 melanoma 9.7
22 leiomyosarcoma 9.7
23 neuroma 9.7
24 chordoma 9.7
25 neurofibromatosis, type 1 9.7
26 lipoma 9.7
27 foramen magnum meningioma 9.7
28 temporal arteritis 9.7

Graphical network of the top 20 diseases related to Occipital Neuralgia:



Diseases related to Occipital Neuralgia

Symptoms & Phenotypes for Occipital Neuralgia

UMLS symptoms related to Occipital Neuralgia:


headache, neuralgia, recurrent paroxysmal headache

Drugs & Therapeutics for Occipital Neuralgia

Drugs for Occipital Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 1 137-58-6 3676
2
Bupivacaine Approved, Investigational Phase 4,Phase 1 2180-92-9, 38396-39-3 2474
3
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
4
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
5
Ondansetron Approved Phase 4 99614-02-5 4595
6
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
7
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
8
Sufentanil Approved, Investigational Phase 4 56030-54-7 41693
9 Anesthetics Phase 4,Phase 1
10 Peripheral Nervous System Agents Phase 4
11 Anesthetics, Local Phase 4
12 Central Nervous System Depressants Phase 4
13 triamcinolone acetonide Phase 4
14 Dexamethasone acetate Phase 4 1177-87-3
15 glucocorticoids Phase 4
16
protease inhibitors Phase 4
17 Gastrointestinal Agents Phase 4
18 Neurotransmitter Agents Phase 4
19 HIV Protease Inhibitors Phase 4
20 Hormone Antagonists Phase 4
21 Dexamethasone 21-phosphate Phase 4
22 Triamcinolone diacetate Phase 4
23 Triamcinolone hexacetonide Phase 4
24 Hormones Phase 4
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4
26 Immunosuppressive Agents Phase 4
27 Antiemetics Phase 4
28 Anti-Inflammatory Agents Phase 4
29 BB 1101 Phase 4
30 Autonomic Agents Phase 4
31 Antineoplastic Agents, Hormonal Phase 4
32 Analgesics Phase 4
33
Serotonin Phase 4 50-67-9 5202
34 Adjuvants, Anesthesia Phase 4
35 Serotonin Agents Phase 4
36 Serotonin Antagonists Phase 4
37 Narcotics Phase 4
38 Sodium Channel Blockers Phase 4
39 Dermatologic Agents Phase 4
40 Analgesics, Opioid Phase 4
41 Tranquilizing Agents Phase 4
42 Anesthetics, Dissociative Phase 4
43 Diuretics, Potassium Sparing Phase 4
44 Anesthetics, General Phase 4
45 Anesthetics, Intravenous Phase 4
46 Anti-Anxiety Agents Phase 4
47 Anti-Arrhythmia Agents Phase 4
48 Excitatory Amino Acid Antagonists Phase 4
49 Excitatory Amino Acids Phase 4
50 Psychotropic Drugs Phase 4

Interventional clinical trials:


id Name Status NCT ID Phase
1 A Comparison of Dexamethasone and Triamcinolone for Ultrasound-guided Occipital C2 Nerve Blocks Recruiting NCT02655523 Phase 4
2 A Prospective Controlled Treatment Trial for Post-Traumatic Headaches Not yet recruiting NCT03007420 Phase 4
3 Postoperative Analgesia in Patients With Microvascular Decompression Not yet recruiting NCT03152955 Phase 4
4 Greater Occipital Nerve Injection Study Completed NCT01988363 Phase 1
5 Study Evaluating the Treatment of Occipital Neuralgia Completed NCT01753765
6 Pulsed Radiofrequency vs. Steroid Injections for Occipital Neuralgia Completed NCT01670825
7 Two US-guided Techniques for Greater Occipital Nerve Blocks Recruiting NCT02031822

Search NIH Clinical Center for Occipital Neuralgia

Genetic Tests for Occipital Neuralgia

Anatomical Context for Occipital Neuralgia

MalaCards organs/tissues related to Occipital Neuralgia:

39
Eye, Dorsal Root Ganglion, B Cells, Medulla Oblongata

Publications for Occipital Neuralgia

Articles related to Occipital Neuralgia:

(show top 50) (show all 145)
id Title Authors Year
1
The treatment of occipital neuralgia: Review of 111 cases. ( 27546882 )
2016
2
Cervical Myelitis Presenting as Occipital Neuralgia. ( 28025377 )
2016
3
Occipital Neuralgia Diagnosis and Treatment: The Role of Ultrasound. ( 26997206 )
2016
4
Intramuscular Lipoma-Induced Occipital Neuralgia on the Lesser Occipital Nerve. ( 27152569 )
2016
5
Neuralgias of the Head: Occipital Neuralgia. ( 27051229 )
2016
6
A case of occipital neuralgia in a vemurafenib-treated melanoma patient. ( 27653311 )
2016
7
Cervical Myelitis Presenting as Occipital Neuralgia. ( 27257286 )
2016
8
Peripheral Nerve Stimulation for Occipital Neuralgia. ( 26365981 )
2015
9
Long-term outcomes of intradural cervical dorsal root rhizotomy for refractory occipital neuralgia. ( 26684782 )
2015
10
Schwannoma of the greater occipital nerve: An uncommon cause of occipital neuralgia. ( 26752925 )
2015
11
Cryoablation for the treatment of occipital neuralgia. ( 26000683 )
2015
12
Occipital neuralgia after hair transplantation and its treatment. ( 25688308 )
2015
13
Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia: Congress of Neurological Surgeons Systematic Review and Evidence-Based Guideline. ( 26125672 )
2015
14
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26186585 )
2015
15
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197206 )
2015
16
Occipital neuralgia secondary to unilateral atlantoaxial osteoarthritis: Case report and review of the literature. ( 26759731 )
2015
17
Randomized, double-blind, comparative-effectiveness study comparing pulsed radiofrequency to steroid injections for occipital neuralgia or migraine with occipital nerve tenderness. ( 26447705 )
2015
18
Distraction Arthrodesis of the C1-C2 Facet Joint with Preservation of the C2 Root for the Management of Intractable Occipital Neuralgia Caused by C2 Root Compression. ( 26731710 )
2015
19
Occipital neuralgia after scalp biopsy and curettage. ( 26265207 )
2015
20
Idiopathic hypertrophic pachymeningitis presenting with occipital neuralgia. ( 25834565 )
2015
21
A simplified CT-guided approach for greater occipital nerve infiltration in the management of occipital neuralgia. ( 25680724 )
2015
22
Occipital neuralgia heralding occipital condyle syndrome revealing vesical leiomyosarcoma skull base metastasis. ( 26411377 )
2015
23
Improvement in clinical outcomes after dry needling in a patient with occipital neuralgia. ( 26136602 )
2015
24
Nurse-led treatment for occipital neuralgia. ( 26455130 )
2015
25
Occipital neuralgia as a sequela of sports concussion: a case series and review of the literature. ( 25574876 )
2015
26
Commentary: Occipital Nerve Stimulation for the Treatment of Patients With Medically Refractory Occipital Neuralgia. ( 26197205 )
2015
27
Successful treatment of occipital neuralgia with implantable peripheral nerve stimulation in a pacemaker-dependent patient. ( 24688344 )
2014
28
C2 nerve root on magnetic resonance imaging of occipital neuralgia. ( 24732835 )
2014
29
Greater occipital nerve excision for occipital neuralgia refractory to nerve decompression. ( 24322636 )
2014
30
Nummular headache in a patient with ipsilateral occipital neuralgia--a case report. ( 24821641 )
2014
31
Occipital neuralgia: Anatomic considerations. ( 25244129 )
2014
32
The intramuscular course of the greater occipital nerve: novel findings with potential implications for operative interventions and occipital neuralgia. ( 25422783 )
2014
33
Cervical myelitis mimicking intractable occipital neuralgia. ( 24465268 )
2014
34
Atlantoaxial Chordoma in Two Patients with Occipital Neuralgia and Cervicalgia. ( 26064862 )
2014
35
Cooled radiofrequency ablation for bilateral greater occipital neuralgia. ( 24716017 )
2014
36
Pulsed radiofrequency for occipital neuralgia. ( 25415786 )
2014
37
Long-term outcome and prognostic factors after C2 ganglion decompression in 68 consecutive patients with intractable occipital neuralgia. ( 25352089 )
2014
38
Occipital neuralgia. ( 24737457 )
2014
39
Ultrasound guided greater occipital nerve blocks for post-traumatic occipital neuralgia. ( 24902462 )
2014
40
Response of Cervicogenic Headaches and Occipital Neuralgia to Radiofrequency Ablation of the C2 Dorsal Root Ganglion and/or Third Occipital Nerve. ( 24433241 )
2014
41
Intractable occipital neuralgia caused by an entrapment in the semispinalis capitis. ( 24278663 )
2013
42
Occipital neuralgia as an unusual manifestation of herpes zoster infection of the lesser occipital nerve: a case report. ( 22975833 )
2013
43
Occipital neuralgia: a symptomatic case caused by an abnormal left vertebral artery. ( 22311642 )
2013
44
Modified C1 lateral mass screw insertion using a high entry point to avoid postoperative occipital neuralgia. ( 23117140 )
2013
45
Noninvasive pulsed radio frequency energy in the treatment of occipital neuralgia with chronic, debilitating headache: a report of four cases. ( 23566238 )
2013
46
Occipital Neuralgia Responding to Palmitoylethanolamide. ( 23701652 )
2013
47
Ultrasound-guided greater occipital nerve blocks and pulsed radiofrequency ablation for diagnosis and treatment of occipital neuralgia. ( 24282778 )
2013
48
Postoperative occipital neuralgia with and without C2 nerve root transection during atlantoaxial screw fixation: a post-hoc comparative outcome study of prospectively collected data. ( 23711959 )
2013
49
Clinical outcomes of pulsed radiofrequency neuromodulation for the treatment of occipital neuralgia. ( 22792425 )
2012
50
Occipital neuralgia as a presenting symptom of gastric cancer metastasis. ( 22711900 )
2012

Variations for Occipital Neuralgia

Expression for Occipital Neuralgia

Search GEO for disease gene expression data for Occipital Neuralgia.

Pathways for Occipital Neuralgia

GO Terms for Occipital Neuralgia

Sources for Occipital Neuralgia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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