MCID: ODN005
MIFTS: 38

Odontogenic Myxoma malady

Rare diseases category

Summaries for Odontogenic Myxoma

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Wikipedia:63 The odontogenic myxoma is an uncommon benign odontogenic tumor arising from embryonic connective tissue... more...

MalaCards based summary: Odontogenic Myxoma is related to periodontitis and granular cell tumor. An important gene associated with Odontogenic Myxoma is ACAN (aggrecan), and among its related pathways are Articular Cartilage Extracellular Matrix and Immune response Oncostatin M signaling via JAK Stat in human cells. The compounds keratan sulfate and dermatan sulfate have been mentioned in the context of this disorder. Affiliated tissues include bone, and related mouse phenotypes are digestive/alimentary and tumorigenesis.

Aliases & Classifications for Odontogenic Myxoma

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Odontogenic Myxoma, Aliases & Descriptions:

Name: Odontogenic Myxoma 41 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Odontogenic Myxoma

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Diseases related to Odontogenic Myxoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 112)
idRelated DiseaseScoreTop Affiliating Genes
1periodontitis30.9MMP9
2granular cell tumor30.8VIM, S100B
3basal cell carcinoma30.7DCN, MMP1, BAK1
4multiple epiphyseal dysplasia10.6ACAN
5syringoma10.5S100B
6osteochondritis dissecans10.5ACAN
7rosai-dorfman disease10.5S100B
8fibromatosis10.5VIM
9adenomatoid tumor10.4VIM
10glomus tumor10.4VIM
11synovitis10.4MMP1, ACAN
12creutzfeldt-jakob disease10.4SERPINA3, S100B
13meningioma, familial10.3S100B, VIM
14fibroma10.3
15gingivitis10.3
16spindle cell sarcoma10.3VIM, S100B
17marfan syndrome10.3CD36, DCN
18myoepithelioma10.3VIM, S100B
19dermatofibrosarcoma protuberans10.3VIM, S100B
20perineurioma10.3VIM, S100B
21epidermolysis bullosa dystrophica10.3CD36, MMP1
22sex cord-gonadal stromal tumor10.3S100B, VIM
23hemangiopericytoma10.3S100B, VIM
24chronic ulcer of skin10.3MMP1, CD36
25hypertensive heart disease10.3CD36, MMP1
26osseous heteroplasia, progressive10.3GNAS, DCN
27malignant mixed mullerian tumor10.3VIM, S100B
28chordoma10.3VIM, S100B
29arthropathy10.3DCN, MMP1, ACAN
30smooth muscle tumor10.3S100B, VIM
31angiosarcoma10.3VIM, SERPINA3
32malignant peripheral nerve sheath tumor10.3S100B, VIM
33acrodysostosis10.3GNAS, PRKAR1A
34mccune-albright syndrome, somatic, mosaic10.3GNAS, PRKAR1A
35fibrous dysplasia10.3GNAS, CD36
36skeletal dysplasia multi-gene panels10.2ACAN, GNAS
37pseudoachondroplasia10.2CD36, ACAN, DCN
38carney complex variant10.2PRKAR1A, GNAS
39ehlers-danlos syndrome10.2CD36, DCN
40thoracic aortic aneurysm10.2MMP1, MMP2
41liver cirrhosis10.2DCN, SERPINA3, COL14A1
42fibrous histiocytoma10.2S100B, VIM, SERPINA3
43secondary hyperparathyroidism of renal origin10.2CD36, PRKAR1A
44malignant fibroxanthoma10.2SERPINA3, VIM, S100B
45adrenal adenoma10.2GNAS, PRKAR1A
46salivary gland adenoid cystic carcinoma10.2SERPINA3, VIM, S100B
47primary hyperparathyroidism10.2CD36, PRKAR1A
48osteogenesis imperfecta10.2CD36, DCN
49parathyroid adenoma10.2GNAS, PRKAR1A
50lymphangioleiomyomatosis10.2MMP2, MMP1

Graphical network of the top 20 diseases related to Odontogenic Myxoma:



Diseases related to odontogenic myxoma

Symptoms for Odontogenic Myxoma

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Drugs & Therapeutics for Odontogenic Myxoma

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Drug clinical trials:

Search ClinicalTrials for Odontogenic Myxoma

Search NIH Clinical Center for Odontogenic Myxoma

Genetic Tests for Odontogenic Myxoma

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Anatomical Context for Odontogenic Myxoma

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MalaCards organs/tissues related to Odontogenic Myxoma:

31
Bone

Animal Models for Odontogenic Myxoma or affiliated genes

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Publications for Odontogenic Myxoma

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Articles related to Odontogenic Myxoma:

(show top 50)    (show all 145)
idTitleAuthorsYear
1
Infant Odontogenic Myxoma: A specific entity. (24429059)
2014
2
A large odontogenic myxoma of the bilateral maxillae: A case report. (25120718)
2014
3
Odontogenic Myxoma: a study based on biopsy material over a 40-year period. (25095832)
2014
4
Surgical treatment of odontogenic myxoma and facial deformity in the same procedure. (24124313)
2013
5
An ectopic tooth concealing an odontogenic myxoma. (23505856)
2013
6
Synchronous occurrence of odontogenic myxoma with multiple keratocystic odontogenic tumors in nevoid basal cell carcinoma syndrome. (24163866)
2013
7
The imaging characteristics of odontogenic myxoma and a comparison of three different imaging modalities. (23972779)
2013
8
Using the condylar prosthesis after resection of a large odontogenic myxoma tumor in the mandible. (22976683)
2012
9
Dental pulp stem cells express proteins involved in the local invasiveness of odontogenic myxoma. (22473349)
2012
10
Conservative treatment of odontogenic myxoma. (21959474)
2011
11
Hypomethylation of tumor suppressor genes in odontogenic myxoma. (22011900)
2011
12
A clinico-pathologic correlation. Odontogenic myxoma. (20806706)
2010
13
Expression of matrix metalloproteinases 2 and 9 in odontogenic myxoma in vivo and in vitro. (18587209)
2008
14
Odontogenic myxoma of maxilla. (18245926)
2008
15
Odontogenic myxoma: clinico-pathological, immunohistochemical and ultrastructural findings of a multicentric series. (17996487)
2008
16
Pediatric maxillary odontogenic myxoma: a report of 2 cases and review of management. (18423302)
2008
17
Problems in diagnosing odontogenic myxoma: case report. (17600984)
2007
18
Odontogenic myxoma of the maxilla: a case report. (18187991)
2007
19
Odontogenic myxoma of the maxilla. (17915662)
2007
20
Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas. (16001434)
2005
21
A rare case of odontogenic myxoma in a dog. (16176569)
2005
22
Application of a surgical navigation system for implant surgery in a deficient alveolar ridge postexcision of an odontogenic myxoma. (16003627)
2005
23
Computed tomography of odontogenic myxoma. (15037142)
2004
24
Oral pathology quiz # 42. Case 3. Odontogenic myxoma. (15160432)
2004
25
Cytologic features of odontogenic myxoma. (15471259)
2004
26
Oral and maxillofacial pathology case of the month. Odontogenic myxoma. (12889417)
2003
27
Oral pathology quiz # 39. Case 1. Odontogenic myxoma. (12861649)
2003
28
Computed tomography of odontogenic myxoma. (12917281)
2003
29
Argyrophilic nucleolar organizer regions (AgNORs) in odontogenic myxoma (OM) and ameloblastic fibroma (AF). (11545240)
2001
30
Odontogenic myxoma of maxillary sinus: CT and MR-pathologic correlation. (11274831)
2001
31
Immunohistochemical and histochemical characterization of the mucosubstances of odontogenic myxoma: histogenesis and differential diagnosis. (10399179)
1999
32
Odontogenic myxoma of the mandible in a filly. (10353360)
1999
33
Odontogenic myxoma. (10587272)
1999
34
Odontogenic myxomas are not associated with activating mutations of the Gs alpha gene. (9891502)
1998
35
Odontogenic myxoma: case report with reconstructive considerations. (9775463)
1998
36
Management of odontogenic myxoma of the maxilla. (9419108)
1997
37
Odontogenic myxoma--characterisation of the extracellular matrix (ECM) of the tumour stroma. (7536506)
1994
38
Odontogenic myxoma of the mandible. Report of a case and review of the literature. (7942346)
1994
39
Maxillary odontogenic myxoma. A case report. (7808718)
1994
40
Odontogenic myxoma: report of two cases with reconstruction considerations. (8336234)
1993
41
Odontogenic myxoma: histochemical and ultrastructural study. (1432734)
1992
42
Re: Odontogenic myxoma. Report of a periodontally-located case. (1622487)
1992
43
Odontogenic myxoma: an orthodontic presentation. (1910983)
1991
44
Odontogenic myxoma: report of a case with peculiar features. (1985190)
1991
45
Proper treatment of odontogenic myxoma. (2709229)
1989
46
Odontogenic myxoma: report of a case. (3294359)
1988
47
Childhood odontogenic myxoma: report of two cases. (3859846)
1985
48
Odontogenic myxoma of the maxilla. (891433)
1977
49
Ultrastructural study of an odontogenic myxoma. (1066602)
1976
50
Odontogenic myxoma: some histochemical considerations. (4163678)
1965

Variations for Odontogenic Myxoma

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Expression for genes affiliated with Odontogenic Myxoma

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Search GEO for disease gene expression data for Odontogenic Myxoma.

Pathways for genes affiliated with Odontogenic Myxoma

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Pathways related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.0ACAN, DCN
29.9MMP1, SERPINA3
39.7DCN, VCAN, ACAN
49.6MMP1, MMP2
59.5MMP1, MMP9
69.3MMP2, MMP9
79.3MMP9, MMP2
89.3MMP2, MMP9
99.3GNAS, PRKAR1A
109.1VCAN, MMP2, BAK1
119.0MMP2, MMP9, DCN
129.0MMP2, MMP9, VCAN
13
Show member pathways
Signaling Pathways in Glioblastoma36
9.0MMP9, MMP2, MMP1
14
Show member pathways
9.0MMP9, MMP2, MMP1
159.0VCAN, MMP9, MMP1, ACAN
168.9MMP9, MMP2, CD36
178.9VCAN, VIM, MMP9, ACAN
188.7MMP1, MMP2, MMP9, DCN
198.6PRKAR1A, MMP1, MMP2, MMP9
20
Show member pathways
8.6MMP9, MMP2, MMP1, PRKAR1A
21
Show member pathways
8.5GNAS, MMP1, PRKAR1A, CD36
22
Show member pathways
Cytoskeleton remodeling FAK signaling58
Development Endothelin 1 EDNRA transactivation of EGFR58
8.5MMP2, MMP9, GNAS
23
Show member pathways
Metalloproteases in connective tissue degradation
8.4VCAN, MMP9, MMP2, MMP1, ACAN
24
Show member pathways
8.4BAK1, PRKAR1A, MMP2, MMP9
25
Show member pathways
8.0GNAS, DCN, VCAN, PRKAR1A, ACAN, CD36
26
Show member pathways
7.9MMP9, MMP2, MMP1, PRKAR1A, COL14A1, CD36
27
Show member pathways
7.8COL14A1, ACAN, MMP1, MMP2, MMP9, VCAN

Compounds for genes affiliated with Odontogenic Myxoma

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Compounds related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 166)
idCompoundScoreTop Affiliating Genes
1keratan sulfate439.6CD36, ACAN, VCAN, DCN
2dermatan sulfate439.4DCN, VCAN, VIM, CD36
3cgs-27023a439.4MMP1, MMP2, MMP9
4prinomastat439.3MMP9, MMP2, MMP1
5ilomastat439.3MMP1, MMP2, MMP9
6hydroxyapatite439.3DCN, VIM, S100B, CD36
7cilomilast439.3MMP9, MMP2, MMP1
8latanoprost43 1210.3MMP9, MMP2, MMP1
9chondroitin sulfate43 2410.2DCN, VCAN, VIM, ACAN, CD36
10alginate439.1DCN, VCAN, MMP2, ACAN, CD36
11hematoxylin439.1VIM, MMP9, MMP1, S100B
12(4-aminophenyl)mercuric acetate439.0MMP9, MMP2, MMP1, CD36
13zoledronic acid439.0MMP9, MMP2, MMP1, CD36
14batimastat43 59 1210.9MMP9, MMP2, MMP1, CD36
153-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide438.9BAK1, S100B, MMP2, MMP9
16heparin43 28 24 1211.8DCN, SERPINA3, VCAN, VIM, S100B, CD36
17pioglitazone28 43 49 1211.7MMP9, MMP2, MMP1, CD36
18hydroxyproline43 24 1210.7CD36, MMP1, MMP2, MMP9, DCN
19glycosaminoglycan438.7DCN, VCAN, MMP9, MMP1, ACAN, CD36
20celecoxib43 59 28 49 24 1213.6MMP9, MMP2, MMP1, BAK1
21vitamin a43 24 1210.6SERPINA3, VIM, MMP9, MMP2, MMP1
22methotrexate49 43 1210.6SERPINA3, VIM, MMP9, MMP2, MMP1
23ag 1478438.5DCN, MMP9, MMP2, BAK1
24cytochalasin d43 599.5CD36, MMP1, MMP2, MMP9, VIM
25leucine438.5GNAS, DCN, SERPINA3, VIM, ACAN, S100B
26troglitazone43 28 59 1211.4MMP9, MMP2, MMP1, BAK1, CD36
27ascorbic acid43 249.4MMP2, MMP1, ACAN, S100B, CD36
28sb 20358043 599.3VIM, MMP9, MMP2, MMP1, ACAN, CD36
29matrigel438.2DCN, VIM, MMP9, MMP2, MMP1, CD36
30genistein43 28 59 2 24 1213.2DCN, VIM, MMP9, MMP2, MMP1, CD36
3112-o-tetradecanoylphorbol 13-acetate438.0MMP9, MMP2, MMP1, BAK1, VIM
32ribonucleic acid437.9GNAS, DCN, MMP9, MMP2, MMP1
33cycloheximide437.8VIM, MMP9, MMP2, MMP1, BAK1, CD36
34glucose437.8GNAS, DCN, SERPINA3, VCAN, PRKAR1A, S100B
35creatinine437.8DCN, SERPINA3, VIM, MMP9, MMP2, MMP1
36tgf beta1437.7VIM, VCAN, DCN, MMP9, MMP2, CD36
37procollagen437.7CD36, COL14A1, ACAN, MMP1, MMP2, MMP9
38progesterone43 28 59 24 1211.7GNAS, SERPINA3, VIM, MMP2, MMP1, S100B
39vegf437.7DCN, VCAN, VIM, MMP9, MMP2, MMP1
40pge2437.6GNAS, DCN, MMP9, MMP2, MMP1, ACAN
41hyaluronic acid43 248.4CD36, COL14A1, ACAN, MMP1, MMP2, MMP9
42glutamate437.3GNAS, DCN, VIM, MMP9, MMP2, PRKAR1A
43paraffin437.2DCN, SERPINA3, VIM, MMP9, MMP2, MMP1
44estrogen437.2DCN, SERPINA3, VIM, MMP9, MMP2, MMP1
45dexamethasone43 49 28 1210.1DCN, SERPINA3, VIM, MMP9, MMP1, PRKAR1A
46alanine437.1GNAS, DCN, SERPINA3, VIM, MMP9, MMP2
47retinoic acid43 248.0MMP9, VIM, SERPINA3, DCN, MMP2, MMP1
48serine436.9GNAS, DCN, SERPINA3, VIM, MMP9, MMP2
49calcium43 49 24 129.6GNAS, SERPINA3, MMP9, MMP2, MMP1, PRKAR1A
50cysteine436.0VIM, SERPINA3, DCN, GNAS, MMP9, MMP2

GO Terms for genes affiliated with Odontogenic Myxoma

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Cellular components related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1Golgi lumenGO:00057969.7ACAN, VCAN, DCN
2lysosomal lumenGO:00432029.4ACAN, VCAN, DCN
3extracellular matrixGO:00310129.3DCN, VCAN, ACAN, COL14A1
4proteinaceous extracellular matrixGO:00055788.2VCAN, MMP9, MMP2, MMP1, ACAN, COL14A1
5extracellular spaceGO:00056158.1DCN, VCAN, MMP9, MMP2, COL14A1, S100B
6extracellular regionGO:00055766.6S100B, GNAS, DCN, SERPINA3, VCAN, MMP9

Biological processes related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

(show all 12)
idNameGO IDScoreTop Affiliating Genes
1dermatan sulfate biosynthetic processGO:003020810.0DCN, VCAN
2chondroitin sulfate catabolic processGO:003020710.0VCAN, DCN
3glycosaminoglycan metabolic processGO:00302039.8ACAN, VCAN, DCN
4chondroitin sulfate biosynthetic processGO:00302069.8VCAN, DCN
5cellular response to glucagon stimulusGO:00713779.3PRKAR1A, GNAS
6embryo implantationGO:00075669.0MMP2, MMP9
7proteolysisGO:00065088.9MMP9, MMP2, MMP1, ACAN
8collagen catabolic processGO:00305748.9COL14A1, MMP1, MMP2, MMP9
9blood coagulationGO:00075968.5GNAS, MMP1, PRKAR1A, CD36
10extracellular matrix disassemblyGO:00226178.4COL14A1, ACAN, MMP1, MMP2, MMP9, DCN
11small molecule metabolic processGO:00442818.2GNAS, DCN, VCAN, PRKAR1A, ACAN, CD36
12extracellular matrix organizationGO:00301988.1DCN, VCAN, MMP9, MMP2, MMP1, ACAN

Molecular functions related to Odontogenic Myxoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hyaluronic acid bindingGO:00055409.9ACAN, VCAN
2glycosaminoglycan bindingGO:00055399.6VCAN, DCN
3collagen bindingGO:00055189.4COL14A1, MMP9, DCN
4metalloendopeptidase activityGO:00042229.0MMP9, MMP2, MMP1
5identical protein bindingGO:00428028.5VIM, MMP9, S100B, BAK1
6protein bindingGO:00055156.2GNAS, SERPINA3, VCAN, VIM, MMP9, MMP2

Products for genes affiliated with Odontogenic Myxoma

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Sources for Odontogenic Myxoma

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3CDC
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