MCID: ODN006
MIFTS: 34

Odontoma malady

Category: Rare diseases

Aliases & Classifications for Odontoma

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Aliases & Descriptions for Odontoma:

Name: Odontoma 48 27 50 68

Classifications:



Summaries for Odontoma

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Wikipedia:71 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

MalaCards based summary: Odontoma is related to odontoma-dysphagia syndrome and calcifying epithelial odontogenic tumor. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways are Signaling mediated by p38-alpha and p38-beta and Primary Focal Segmental Glomerulosclerosis FSGS. Affiliated tissues include bone and testes, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and digestive/alimentary.

Related Diseases for Odontoma

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Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 102)
idRelated DiseaseScoreTop Affiliating Genes
1odontoma-dysphagia syndrome12.2
2calcifying epithelial odontogenic tumor10.8
3evc-related ellis-van creveld syndrome10.3KRT14, KRT5
4pachyonychia congenita 410.3KRT14, KRT5
5mental retardation, autosomal recessive 4910.3KRT14, KRT8
6epidermylysis bullosa simplex-mcr10.3KRT14, KRT5
7sed congenita10.3KRT14, KRT5
8lin-gettig syndrome10.3KRT14, KRT5
9darier disease10.3KRT14, KRT5
10ebola hemorrhagic fever10.3KRT14, KRT5
11mixed cell adenoma10.3KRT14, KRT5
12prostate lymphoma10.3KRT5, KRT8
13dowling-degos disease 110.3KRT14, KRT5
14aml with myelodysplasia-related features10.3KRT14, VIM
15conjunctival cancer10.2KRT14, VIM
16basaloid squamous cell carcinoma10.2KRT14, KRT5
17female breast axillary tail cancer10.2KRT14, KRT5
18breast granular cell tumor10.2KRT14, KRT5
19middle ear adenocarcinoma10.2KRT5, KRT8
20testicular granulosa cell tumor10.2KRT14, VIM
21nephrogenic adenoma of urinary bladder10.2NES, VIM
22adult brainstem gliosarcoma10.2NES, VIM
23male reproductive system disease10.2NES, VIM
24mediastinum liposarcoma10.2KRT8, VIM
25duodenal obstruction10.2KRT5, KRT8
26adult pineal parenchymal tumor10.2KRT8, VIM
27maple syrup urine disease, mild variant10.2KRT8, VIM
28bilirubin metabolic disorder10.2KRT14, KRT5
29thymus squamous cell carcinoma10.2KRT14, KRT8
30subependymal glioma10.2KRT14, VIM
31calcific tendinitis10.2NES, VIM
32lymphomatous thyroiditis10.2PCNA, VIM
33appendix adenocarcinoma10.2PCNA, VIM
34adenoid squamous cell carcinoma10.2KRT5, KRT8
35behcet's syndrome arthropathy10.2PCNA, VIM
36chondroblastoma10.2KRT5, VIM
37occipital encephalocele10.2KRT18, KRT8
38woolly hair, autosomal dominant10.2KRT18, KRT8
39clear cell cystadenofibroma10.2KRT14, KRT5, KRT8
40appendix mucinous cystadenocarcinoma10.2PCNA, VIM
41vulva adenocarcinoma10.2KRT14, KRT5, KRT8
42progesterone-receptor positive breast cancer10.2KRT14, KRT5, KRT8
43multidrug-resistant tuberculosis10.2KRT18, KRT5
44ovarian embryonal carcinoma10.1KRT18, KRT8
45progressive multifocal leukoencephalopathy10.1KRT18, VIM
46nasal cavity adenocarcinoma10.1KRT5, KRT8
47differentiating neuroblastoma10.1TUBB3, VIM
48dissociative amnesia10.1KRT19, KRT8
49retrograde amnesia10.1KRT14, KRT5, PCNA
50heavy chain disease10.1KRT14, KRT5

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to odontoma

Symptoms & Phenotypes for Odontoma

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GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-8410.0KRT18, KRT5, KRT8

MGI Mouse Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.5KRT14, KRT19, KRT5, KRT8, LHX8
2MP:00107686.7KRT14, KRT18, KRT19, KRT5, KRT8, LHX8

Drugs & Therapeutics for Odontoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

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Genetic tests related to Odontoma:

id Genetic test Affiliating Genes
1 Odontoma27

Anatomical Context for Odontoma

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MalaCards organs/tissues related to Odontoma:

36
Bone, Testes

Publications for Odontoma

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Articles related to Odontoma:

(show top 50)    (show all 511)
idTitleAuthorsYear
1
Archegonous Cystic Odontoma Is Not Necessarily Primordial. (26843411)
2016
2
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. (26981293)
2016
3
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? (27098720)
2016
4
Odontoma in a 255-Million-Year-Old Mammalian Forebear. (27930769)
2016
5
Dentigerous cyst arising from a complex odontoma: an unusual presentation. (27090549)
2016
6
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. (27790601)
2016
7
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. (27514999)
2016
8
Multiple complex odontoma of the maxilla and mandible-reply. (26972543)
2016
9
Management of a massive compound odontoma in a 9-year child. (27630512)
2016
10
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. (27563600)
2016
11
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). (26709130)
2016
12
Complex Odontoma: A Case Report with Micro-Computed Tomography Findings. (27293913)
2016
13
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. (26825866)
2016
14
Management of a Compound Odontoma in the Primary Dentition. (27620522)
2016
15
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. (27307963)
2016
16
Compound odontoma associated with impacted maxillary central incisor dictates a need to be vigilant to canine eruption pattern: A 2-year follow-up. (27307685)
2016
17
Diagnostic Discussion. Ameloblastic fibro-odontoma. (27024969)
2016
18
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. (28025437)
2016
19
Extensive Mandibular Ameloblastic Fibro-Odontoma. (27428924)
2016
20
An Erupted Dilated Odontoma: A Rare Presentation. (26989523)
2016
21
Response to the Letter Entitled "Archegonous Cystic Odontoma Is Not Necessarily Primordial" by Ide et al. (26857026)
2016
22
Compound composite odontoma. (27194882)
2016
23
Dilated odontoma: A report of two cases from a radiological perspective. (27041914)
2016
24
Multiple complex odontoma of the maxilla and the mandible. (25921711)
2015
25
Primordial Odontogenic Cyst with Induction Phenomenon (Zonal Fibroblastic Hypercellularity) and Dentinoid Material Versus Archegonous Cystic Odontoma: You Choose! (26156422)
2015
26
Super odontoma - a destructive swarm entity. (25954721)
2015
27
'Dilated odontoma': an incidental finding. (26452745)
2015
28
Impacted permanent incisors associated with compound odontoma. (25583937)
2015
29
Compound Odontoma in a Pediatric Patient With Aspects Similar to Complex Odontoma. (26080222)
2015
30
Unusually large erupted complex odontoma: A rare case report. (25793183)
2015
31
Post-Odontoma autotransplantation of an impacted tooth: A case report. (26258027)
2015
32
Ameloblastic fibro-odontoma. (26045519)
2015
33
An alternative treatment option for a bony defect from large odontoma using recycled demineralization at chairside. (25922824)
2015
34
Bilateral coronoid hypoplasia and complex odontoma: a rare concurrence of developmental pathology and odontogenic tumour of the mandible. (26464410)
2015
35
Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma. (26289508)
2015
36
Surgical Management of Compound Odontoma Associated with Unerupted Tooth. (26199762)
2015
37
Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation. (26411543)
2015
38
Discussion: An alternative treatment option for a bony defect from large odontoma using recycled demineralization at chairside. (25922825)
2015
39
Ectopic compound odontoma in the buccal mucosa: report of a rare case. (25810930)
2015
40
Erupted complex odontoma of the posterior maxilla: A rarity. (26604611)
2015
41
Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management. (25848139)
2015
42
Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review. (26612404)
2015
43
Cystic Odontoma in a Patient with Hodgkin's Lymphoma. (26618008)
2015
44
Giant complex odontoma in maxillary sinus. (26389051)
2015
45
Histopathological insight of complex odontoma associated with a dentigerous cyst. (24488658)
2014
46
Erupted odontoma: a case report. (25177649)
2014
47
Ameloblastic fibro-odontoma. (25437658)
2014
48
Compound odontoma involving the four quadrants of the jaws: a case report and review of the literature. (24459676)
2014
49
Calcifying cystic odontogenic tumor associated with ameloblastic fibro-odontoma of the anterior mandible. (24785751)
2014
50
An erupted compound odontoma. (24729109)
2014

Variations for Odontoma

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Expression for genes affiliated with Odontoma

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Search GEO for disease gene expression data for Odontoma.

Pathways for genes affiliated with Odontoma

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GO Terms for genes affiliated with Odontoma

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Cellular components related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1apicolateral plasma membraneGO:001632710.4KRT19, KRT8
2costamereGO:004303410.4KRT19, KRT8
3dystrophin-associated glycoprotein complexGO:001601010.4KRT19, KRT8
4cell peripheryGO:00719449.0KRT14, KRT18, KRT19, KRT8, TUBB3
5keratin filamentGO:00450958.9KRT14, KRT18, KRT5, KRT8
6intermediate filamentGO:00058828.1KRT14, KRT18, KRT19, KRT5, KRT8, NES
7extracellular exosomeGO:00700627.6KRT14, KRT18, KRT19, KRT5, KRT8, PCNA

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1hemidesmosome assemblyGO:003158110.5KRT14, KRT5
2cell differentiation involved in embryonic placenta developmentGO:006070610.3KRT19, KRT8
3sarcomere organizationGO:004521410.3KRT19, KRT8
4extrinsic apoptotic signaling pathwayGO:009719110.2KRT18, KRT8
5hepatocyte apoptotic processGO:009728410.2KRT18, KRT8
6cornificationGO:00702689.0KRT14, KRT18, KRT19, KRT5, KRT8
7keratinizationGO:00314249.0KRT14, KRT18, KRT19, KRT5, KRT8
8viral processGO:00160328.6KRT18, KRT19, KRT8, VIM

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filament bindingGO:199025410.4KRT14, VIM
2scaffold protein bindingGO:00971109.4KRT18, KRT5, KRT8, VIM
3structural constituent of cytoskeletonGO:00052008.9KRT14, KRT19, KRT5, TUBB3, VIM
4structural molecule activityGO:00051988.8KRT18, KRT8, NES, VIM

Sources for Odontoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet