Aliases & Classifications for Odontoma

MalaCards integrated aliases for Odontoma:

Name: Odontoma 50 29 52 69

Classifications:



Summaries for Odontoma

MalaCards based summary : Odontoma is related to odontoma-dysphagia syndrome and encephalocraniocutaneous lipomatosis. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways/superpathways are Keratinization and Cytoskeletal Signaling. Affiliated tissues include bone and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and mortality/aging

Wikipedia : 72 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

Related Diseases for Odontoma

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 122)
id Related Disease Score Top Affiliating Genes
1 odontoma-dysphagia syndrome 12.2
2 encephalocraniocutaneous lipomatosis 11.1
3 calcifying epithelial odontogenic tumor 10.8
4 trichoepithelioma, multiple familial, 1 10.7 KRT14 KRT8
5 familial periodic paralysis 10.7 KRT5 KRT8
6 ercc2-related xeroderma pigmentosum 10.7 KRT14 KRT5
7 pachyonychia congenita 3 10.7 KRT14 KRT5
8 dowling-degos disease 1 10.7 KRT14 KRT5
9 light chain deposition disease 10.7 KRT14 KRT5
10 acantholytic acanthoma 10.6 KRT14 KRT5
11 epidermolysis bullosa simplex-mp 10.6 KRT14 KRT5
12 sed, maroteaux type 10.6 KRT14 KRT5
13 female breast axillary tail cancer 10.6 KRT14 KRT5
14 lobular neoplasia 10.6 KRT14 KRT5
15 penis squamous cell carcinoma 10.6 KRT14 KRT5
16 kidney clear cell sarcoma 10.6 KRT5 KRT8
17 middle ear squamous cell carcinoma 10.6 KRT14 KRT8
18 superior mesenteric artery syndrome 10.6 KRT5 KRT8
19 colon squamous cell carcinoma 10.6 KRT5 KRT8
20 bilirubin metabolic disorder 10.6 KRT14 KRT5
21 klatskin's tumor 10.6 KRT5 KRT8
22 epidermolysis bullosa simplex, koebner type 10.6 KRT14 KRT5
23 levy-yeboa syndrome 10.6 KRT8 PCNA
24 connective tissue benign neoplasm 10.6 KRT14 KRT5
25 amelogenesis imperfecta local hypoplastic 10.6 KRT14 VIM
26 comedo carcinoma 10.6 KRT14 KRT5
27 spindle cell liposarcoma 10.6 KRT8 VIM
28 lymphocytic infiltrate of jessner 10.5 PCNA VIM
29 appendix mucinous cystadenocarcinoma 10.5 PCNA VIM
30 fallopian tube germ cell cancer 10.5 KRT14 VIM
31 aflatoxins-related hepatocellular carcinoma 10.5 KRT8 VIM
32 eccrine sweat gland neoplasm 10.5 KRT5 TUBB3
33 behcet's syndrome arthropathy 10.5 PCNA VIM
34 childhood oligodendroglioma 10.5 KRT5 PCNA
35 skin papilloma 10.5 KRT5 VIM
36 pulmonary venoocclusive disease 10.5 KRT14 VIM
37 ovarian mucinous adenocarcinoma 10.5 PCNA VIM
38 lacrimal gland mucoepidermoid carcinoma 10.5 KRT14 KRT5
39 cervical spina bifida cystica 10.4 KRT18 KRT8
40 hypotrichosis 13 10.4 KRT18 KRT8
41 retinal disease 10.4 KRT5 KRT8
42 secondary syphilis 10.4 TUBB3 VIM
43 hip subluxation 10.4 KRT5 VIM
44 microcystic meningioma 10.4 KRT8 VIM
45 chondroblastoma 10.4 KRT5 VIM
46 congenital hemolytic anemia 10.4 KRT14 KRT5 KRT8
47 ductal carcinoma in situ 10.4 KRT14 KRT5 KRT8
48 vulva adenocarcinoma 10.4 KRT14 KRT5 KRT8
49 extragonadal nonseminomatous germ cell tumor 10.4 KRT18 KRT8
50 mitochondrial myopathy with lactic acidosis 10.4 KRT5 VIM

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to Odontoma

Symptoms & Phenotypes for Odontoma

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.47 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.47 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.47 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.47 KRT5 KRT8
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.47 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.47 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.47 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.47 KRT5 KRT8 KRT18
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.47 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.47 KRT5

MGI Mouse Phenotypes related to Odontoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.28 KRT8 LHX8 PCNA TUBB3 VIM KRT14

Drugs & Therapeutics for Odontoma

Search Clinical Trials , NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

Genetic tests related to Odontoma:

id Genetic test Affiliating Genes
1 Odontoma 29

Anatomical Context for Odontoma

MalaCards organs/tissues related to Odontoma:

39
Bone, Testes

Publications for Odontoma

Articles related to Odontoma:

(show top 50) (show all 525)
id Title Authors Year
1
An unusual foreign object mimicking an odontoma in a patient with cleft alveolus: a case report. ( 28946895 )
2017
2
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla. ( 28863377 )
2017
3
Giant Complex Odontoma of Mandible: A Spectacular Case Report. ( 28839489 )
2017
4
Ameloblastic Fibro-Odontoma of the Maxilla in a Pierre-Robin Sequence Patient. ( 28557592 )
2017
5
Ameloblastic Fibrodentinoma and Ameloblastic Fibro-Odontoma: An Updated Systematic Review of Cases Reported in the Literature. ( 28153756 )
2017
6
Association Between Odontoma and Impacted Teeth. ( 28106699 )
2017
7
Removal of Compound Odontoma With Piezosurgery Technique. ( 28278140 )
2017
8
Association Between Odontoma and Impacted Teeth. ( 28468159 )
2017
9
Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report. ( 28151902 )
2017
10
Autotransplantation of Odontoma-Associated Impacted Teeth-A Treatment Strategy for Satisfying Immediate Esthetic Demands: A Case Report. ( 28460214 )
2017
11
Immediate Dental Implant Placement After Removal of Complex Odontoma. ( 28922246 )
2017
12
Compound Odontoma in Anterior Mandible-A Case Report. ( 28814937 )
2017
13
Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat. ( 28503263 )
2017
14
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. ( 27563600 )
2016
15
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). ( 26709130 )
2016
16
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. ( 26825866 )
2016
17
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. ( 27307963 )
2016
18
Complex Odontoma: A Case Report with Micro-Computed Tomography Findings. ( 27293913 )
2016
19
Odontoma in a 255-Million-Year-Old Mammalian Forebear. ( 27930769 )
2016
20
Management of a massive compound odontoma in a 9-year child. ( 27630512 )
2016
21
Compound composite odontoma. ( 27194882 )
2016
22
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? ( 27098720 )
2016
23
Archegonous Cystic Odontoma Is Not Necessarily Primordial. ( 26843411 )
2016
24
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. ( 28025437 )
2016
25
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. ( 27514999 )
2016
26
Compound odontoma associated with impacted maxillary central incisor dictates a need to be vigilant to canine eruption pattern: A 2-year follow-up. ( 27307685 )
2016
27
Dilated odontoma: A report of two cases from a radiological perspective. ( 27041914 )
2016
28
Dentigerous cyst arising from a complex odontoma: an unusual presentation. ( 27090549 )
2016
29
Diagnostic Discussion. Ameloblastic fibro-odontoma. ( 27024969 )
2016
30
Extensive Mandibular Ameloblastic Fibro-Odontoma. ( 27428924 )
2016
31
Response to the Letter Entitled "Archegonous Cystic Odontoma Is Not Necessarily Primordial" by Ide et al. ( 26857026 )
2016
32
An Erupted Dilated Odontoma: A Rare Presentation. ( 26989523 )
2016
33
Management of a Compound Odontoma in the Primary Dentition. ( 27620522 )
2016
34
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. ( 26981293 )
2016
35
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. ( 27790601 )
2016
36
Multiple complex odontoma of the maxilla and mandible-reply. ( 26972543 )
2016
37
Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin. ( 28163488 )
2016
38
Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation. ( 26411543 )
2015
39
Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review. ( 26612404 )
2015
40
Surgical Management of Compound Odontoma Associated with Unerupted Tooth. ( 26199762 )
2015
41
Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management. ( 25848139 )
2015
42
Ameloblastic fibro-odontoma. ( 26045519 )
2015
43
Bilateral coronoid hypoplasia and complex odontoma: a rare concurrence of developmental pathology and odontogenic tumour of the mandible. ( 26464410 )
2015
44
An alternative treatment option for a bony defect from large odontoma using recycled demineralization at chairside. ( 25922824 )
2015
45
Multiple complex odontoma of the maxilla and the mandible. ( 25921711 )
2015
46
Super odontoma - a destructive swarm entity. ( 25954721 )
2015
47
Impacted permanent incisors associated with compound odontoma. ( 25583937 )
2015
48
Ectopic compound odontoma in the buccal mucosa: report of a rare case. ( 25810930 )
2015
49
Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma. ( 26289508 )
2015
50
Post-Odontoma autotransplantation of an impacted tooth: A case report. ( 26258027 )
2015

Variations for Odontoma

Expression for Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for Odontoma

GO Terms for Odontoma

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 KRT14 KRT18 KRT19 KRT5 KRT8 PCNA
2 keratin filament GO:0045095 9.46 KRT14 KRT18 KRT5 KRT8
3 apicolateral plasma membrane GO:0016327 9.4 KRT19 KRT8
4 costamere GO:0043034 9.37 KRT19 KRT8
5 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT19 KRT8
6 cell periphery GO:0071944 9.26 KRT14 KRT18 KRT19 KRT8
7 intermediate filament GO:0005882 9.17 KRT14 KRT18 KRT19 KRT5 KRT8 NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.67 KRT18 KRT19 KRT8 VIM
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT18 KRT8
3 sarcomere organization GO:0045214 9.4 KRT19 KRT8
4 keratinization GO:0031424 9.35 KRT14 KRT18 KRT19 KRT5 KRT8
5 hepatocyte apoptotic process GO:0097284 9.32 KRT18 KRT8
6 hemidesmosome assembly GO:0031581 9.26 KRT14 KRT5
7 cell differentiation involved in embryonic placenta development GO:0060706 9.16 KRT19 KRT8
8 cornification GO:0070268 9.02 KRT14 KRT18 KRT19 KRT5 KRT8

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.56 KRT18 KRT8 NES VIM
2 scaffold protein binding GO:0097110 9.26 KRT18 KRT5 KRT8 VIM
3 keratin filament binding GO:1990254 9.16 KRT14 VIM
4 structural constituent of cytoskeleton GO:0005200 9.02 KRT14 KRT19 KRT5 TUBB3 VIM

Sources for Odontoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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30 HGMD
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32 HPO
33 ICD10
34 ICD10 via Orphanet
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43 MESH via Orphanet
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59 PubMed
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65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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