MCID: ODN006
MIFTS: 31

Odontoma malady

Rare diseases category

Summaries for Odontoma

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Wikipedia:65 An odontoma is a benign tumour of odontogenic origin (i.e. linked to tooth development). Specifically,... more...

MalaCards based summary: Odontoma is related to ameloblastoma and fibroma. An important gene associated with Odontoma is LHX8 (LIM homeobox 8), and among its related pathways is Endometrial cancer. The compounds silver and formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include bone and testes, and related mouse phenotype craniofacial.

Aliases & Classifications for Odontoma

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Sources:
43NIH Rare Diseases, 45Novoseek, 62UMLS
See all sources

Odontoma, Aliases & Descriptions:

Name: Odontoma 43 45 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Related Diseases for Odontoma

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Diseases related to Odontoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 21)
idRelated DiseaseScoreTop Affiliating Genes
1ameloblastoma30.3PCNA, DSPP
2fibroma10.4
3odontoma dysphagia syndrome10.3
4sinusitis10.3
5pericoronitis10.1
6gingivitis10.1
7lipomatosis10.1
8adenoameloblastoma10.1
9encephalocraniocutaneous lipomatosis10.1
10adenomatous polyposis coli10.0
11osteopetrosis10.0
12sialolithiasis10.0
13actinomycosis10.0
14acute maxillary sinusitis10.0
15ludwig's angina10.0
16amyloidosis10.0
17cellulitis10.0
18neuropathy10.0
19dysphagia10.0
20prostate cancer10.0PCNA, DSPP
21cleft palate, isolated10.0DSPP, LHX8

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to odontoma

Symptoms for Odontoma

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Drugs & Therapeutics for Odontoma

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Drug clinical trials:

Search ClinicalTrials for Odontoma

Search NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

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Anatomical Context for Odontoma

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MalaCards organs/tissues related to Odontoma:

33
Bone, Testes

Animal Models for Odontoma or affiliated genes

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MGI Mouse Phenotypes related to Odontoma:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.5DSPP, LEF1, LHX8

Publications for Odontoma

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Articles related to Odontoma:

(show top 50)    (show all 469)
idTitleAuthorsYear
1
Unusually large erupted complex odontoma: A rare case report. (25793183)
2015
2
Ameloblastic fibro-odontoma. (25437658)
2014
3
Compound composite odontoma and its management. (25587458)
2014
4
Pathology in practice. Compound odontoma in a horse. (24479454)
2014
5
A Large Ameloblastic Fibro-odontoma of the Maxillary Sinus. (24745000)
2014
6
Complex composite odontoma with characteristic histology. (23840973)
2013
7
Compound odontoma in deciduous dentition. (23919208)
2013
8
Erupted composite odontoma associated with malformed teeth - unusual dental aberrations following maxillofacial trauma. (24399016)
2013
9
Aggressive ameloblastic fibro-odontoma assessment with CBCT and treatment. (23633233)
2013
10
Orthokeratinizing odontogenic cyst of maxilla with complex odontoma. (24574683)
2013
11
Ameloblastic fibroma: a stage in the development of a hamartomatous odontoma or a true neoplasm? Critical analysis of 162 previously reported cases plus 10 new cases. (24055148)
2013
12
Compound odontoma. (22629054)
2012
13
Odontoma-associated tooth impaction: accurate diagnosis with simple methods? Case report and literature review. (22883320)
2012
14
Peripheral ameloblastic fibro-odontoma or peripheral developing complex odontoma: report of a case. (21689175)
2011
15
Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. (20116726)
2010
16
Compound odontoma. (20533004)
2010
17
Importance of cone beam computed tomography for diagnosis of calcifying cystic odontogenic tumour associated to odontoma. Report of a case. (20038909)
2010
18
Multiple supernumerary teeth and odontoma in the maxilla: A case report. (22114378)
2010
19
Oral pathology quiz #69. Case number 2. Odontoma. (21341407)
2010
20
Oral Pathology Quiz #62. Case number 4. Ameloblastic fibro-odontoma. (19445048)
2009
21
The use of digital volume tomography in imaging an unusually large composite odontoma in the mandible. (19947141)
2009
22
Radiology quiz case. Complex odontoma of the maxillary sinus. (18559738)
2008
23
Odontomas in pediatric dentistry: report of two cases. (16491972)
2005
24
Surgical management of a large complex odontoma of the mandibular angle-ramus region through intra-oral buccal approach--A case report. (16380746)
2005
25
Surgical management of compound odontoma in two horses. (15552320)
2004
26
Rare compound odontoma of the mandible in a 7-year-old child: case report. (14725505)
2003
27
Calcifying odontogenic cyst in infancy: report of case associated with compound odontoma. (7775688)
1995
28
Calcifying odontogenic cyst associated with compound odontoma: a study on undemineralized material. (7492892)
1995
29
Bilateral complex odontoma in a Swiss (CD-1) male mouse. (8158975)
1994
30
Ameloblastic fibro-odontoma of the anterior maxilla. Report of a case. (8378043)
1993
31
Morphodifferentiation and histodifferentiation of the dental hard tissues in compound odontoma: a study of undemineralized material. (1403841)
1992
32
An erupted odontoma: case report. (2760735)
1989
33
Ameloblastic fibro-odontoma. Case report. (2705938)
1989
34
Compound composite odontoma--a case report. (3473134)
1986
35
Odontoma of a maxillary central incisor in a 10-year old black male. (2980418)
1986
36
Compound odontoma--a case report. (3458819)
1986
37
Cholesterol granuloma embedded in an odontoma of the maxilla. (6585505)
1984
38
Odontoma in the subcondylar region. (298840)
1979
39
Transantral odontoma. A case report. (282542)
1978
40
Calcified odontoma. (275497)
1977
41
Compound odontoma in a 6-year-old girl; a case report. (266498)
1977
42
Ameloblastic odontoma in rats induced by N-butylnitrosourea. (1181232)
1975
43
Odontoma containing ghost cells in the maxillary sinus. (4530972)
1974
44
Compound composite odontoma. (4520183)
1973
45
A midpalatal compound odontoma in an infant. (5263262)
1970
46
Radiographic survey of a composite odontoma growth during five years. Report of a case. (5259675)
1969
47
A MELANOTIC AMELOBLASTIC ODONTOMA. (14237105)
1965
48
Complex-compound odontoma: report of case. (13976167)
1963
49
Ameloblastic odontoma. Report of a case. (14018994)
1963
50
Odontoma of maxilla; report of case. (14825010)
1951

Variations for Odontoma

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Expression for genes affiliated with Odontoma

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Search GEO for disease gene expression data for Odontoma.

Pathways for genes affiliated with Odontoma

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Pathways related to Odontoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signal transduction PTEN pathway60
9.1PCNA, LEF1

Compounds for genes affiliated with Odontoma

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Compounds related to Odontoma according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1silver459.6PCNA, DSPP
2formaldehyde45 2610.5DSPP, PCNA
3carbon459.5PCNA, DSPP
4glycerol45 26 1311.5PCNA, DSPP
5epinephrine45 26 1311.4DSPP, PCNA
6ascorbic acid45 2610.4PCNA, DSPP
7paraffin459.3PCNA, DSPP
8aspartate459.3PCNA, DSPP
9lactate459.2DSPP, PCNA
10cisplatin45 51 61 1311.8PCNA, LEF1
11alanine458.7PCNA, DSPP, LEF1

GO Terms for genes affiliated with Odontoma

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Biological processes related to Odontoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1odontogenesis of dentin-containing toothGO:00424759.1LEF1, LHX8

Molecular functions related to Odontoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sequence-specific DNA bindingGO:00435659.1LEF1, LHX8

Products for genes affiliated with Odontoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Odontoma

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet