MCID: ODN006
MIFTS: 34

Odontoma malady

Category: Rare diseases

Aliases & Classifications for Odontoma

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Aliases & Descriptions for Odontoma:

Name: Odontoma 47 26 49 67

Classifications:



Summaries for Odontoma

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Wikipedia:70 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

MalaCards based summary: Odontoma is related to odontoma-dysphagia syndrome and calcifying epithelial odontogenic tumor. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways are Signaling mediated by p38-alpha and p38-beta and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone and testes, and related mouse phenotypes are digestive/alimentary and mortality/aging.

Related Diseases for Odontoma

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Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1odontoma-dysphagia syndrome12.2
2calcifying epithelial odontogenic tumor10.8
3familial periodic paralysis10.5KRT5, KRT8
4mental retardation, autosomal recessive 4910.5KRT14, KRT8
5pachyonychia congenita 310.5KRT14, KRT5
6dowling-degos disease 110.5KRT14, KRT5
7quinquaud's decalvans folliculitis10.5KRT14, KRT5
8epidermolytic acanthoma10.5KRT14, KRT5
9sed congenita10.5KRT14, KRT5
10male reproductive organ cancer10.5KRT14, KRT8
11hemoglobin d disease10.5KRT14, KRT5
12benign intermediate mesothelioma10.5KRT14, KRT5
13gastric squamous cell carcinoma10.5KRT14, KRT5
14female breast lower-inner quadrant cancer10.5KRT14, KRT5
15breast neuroendocrine neoplasm10.5KRT14, KRT5
16mast-cell sarcoma10.5KRT5, KRT8
17darier disease10.5KRT14, KRT5
18epidermolysis bullosa simplex-mp10.5KRT14, KRT5
19prostatic acinar adenocarcinoma10.5KRT14, KRT8
20anal squamous cell carcinoma10.5KRT14, KRT8
21gilbert syndrome10.5KRT14, KRT5
22epidermal nevus vitamin d resistant rickets10.4KRT8, VIM
23amelogenesis imperfecta local hypoplastic10.4KRT14, VIM
24bronchiolo-alveolar adenocarcinoma10.4KRT5, KRT8
25sclerosing liposarcoma10.4KRT8, VIM
26connective tissue benign neoplasm10.4KRT14, KRT5
27papillary adenoma10.4KRT14, KRT5
28lymphocytic vasculitis10.4PCNA, VIM
29ovarian mucinous adenocarcinoma10.4PCNA, VIM
30bartholin's gland benign neoplasm10.4KRT14, VIM
31vulvar alveolar soft part sarcoma10.4KRT14, VIM
32eccrine papillary adenoma10.4KRT14, VIM
33colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas10.4KRT14, KRT5
34pleomorphic carcinoma10.4KRT14, KRT5
35hyperinsulinemic hypoglycemia, familial, 410.4KRT8, VIM
36malignant cystic nephroma10.4KRT5, VIM
37ovarian cystadenocarcinoma10.4PCNA, VIM
38nerve fibre bundle defect10.4KRT5, KRT8
39pediatric meningioma10.4KRT8, VIM
40short stature-deafness-neutrophil dysfunction-dysmorphism syndrome10.3KRT18, KRT8
41hypotrichosis 1310.3KRT18, KRT8
42ductal carcinoma in situ10.3KRT14, KRT5
43centrotemporal epilepsy10.3LHX8, PCNA
44primary syphilis10.3TUBB3, VIM
45vulval paget's disease10.3KRT14, KRT5, KRT8
46sm-ahnmd10.3NES, VIM
47novak syndrome10.3KRT5, VIM
48ependymoblastoma10.2NES, VIM
49bone squamous cell carcinoma10.2KRT14, KRT8
50trochlear nerve neoplasm10.2KRT5, NES

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to odontoma

Symptoms for Odontoma

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Drugs & Therapeutics for Odontoma

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

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Genetic tests related to Odontoma:

id Genetic test Affiliating Genes
1 Odontoma26

Anatomical Context for Odontoma

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MalaCards organs/tissues related to Odontoma:

35
Bone, Testes

Animal Models for Odontoma or affiliated genes

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MGI Mouse Phenotypes related to Odontoma:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.4KRT14, KRT19, KRT5, KRT8, LHX8
2MP:00107686.4KRT14, KRT18, KRT19, KRT5, KRT8, LHX8

Publications for Odontoma

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Articles related to Odontoma:

(show top 50)    (show all 511)
idTitleAuthorsYear
1
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. (27563600)
2016
2
Diagnostic Discussion. Ameloblastic fibro-odontoma. (27024969)
2016
3
Cystic Odontoma in a Patient with Hodgkin's Lymphoma. (26618008)
2015
4
Ameloblastic fibro-odontoma. (25437658)
2014
5
Compound composite odontoma and its management. (25587458)
2014
6
Pathology in practice. Compound odontoma in a horse. (24479454)
2014
7
Histopathological insight of complex odontoma associated with a dentigerous cyst. (24488658)
2014
8
Complex composite odontoma with characteristic histology. (23840973)
2013
9
Erupted composite odontoma associated with malformed teeth - unusual dental aberrations following maxillofacial trauma. (24399016)
2013
10
Aggressive ameloblastic fibro-odontoma assessment with CBCT and treatment. (23633233)
2013
11
Orthokeratinizing odontogenic cyst of maxilla with complex odontoma. (24574683)
2013
12
Ameloblastic fibroma: a stage in the development of a hamartomatous odontoma or a true neoplasm? Critical analysis of 162 previously reported cases plus 10 new cases. (24055148)
2013
13
Temporal Odontoma: A Unique Finding. (24366471)
2013
14
Compound odontoma. (22629054)
2012
15
Re: Pontes HA, Pontes FS, Lameira AG, Salim RA, Carvalho PL, GuimarALes DM, Pinto Ddos S Jr.: Report of four cases of ameloblastic fibro-odontoma in mandible and discussion of the literature about the treatment. J Craniomaxillofac Surg 40(2): e59-e63, 2012 Feb. Epub 2011 Apr 15. (22531299)
2012
16
Ameloblastic fibro-odontoma in children: report of 2 cases. (22126932)
2011
17
Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. (20116726)
2010
18
Compound odontoma. (20533004)
2010
19
Importance of cone beam computed tomography for diagnosis of calcifying cystic odontogenic tumour associated to odontoma. Report of a case. (20038909)
2010
20
Multiple supernumerary teeth and odontoma in the maxilla: A case report. (22114378)
2010
21
Small peripheral developing odontoma of the maxilla in a 3-year-old patient depicted on cone-beam tomograms. (21164051)
2010
22
Oral Pathology Quiz #62. Case number 4. Ameloblastic fibro-odontoma. (19445048)
2009
23
Odontoma-like Malformation of the Primary Tooth Germ [corrected]. (19208029)
2009
24
Radiology quiz case. Complex odontoma of the maxillary sinus. (18559738)
2008
25
Surgical management of compound odontoma in a dog. (17691534)
2007
26
Oral pathology quiz #4. Case number 4. Odontoma. (18273991)
2007
27
Odontomas in pediatric dentistry: report of two cases. (16491972)
2005
28
Delayed eruption of a mandibular primary cuspid associated with compound odontoma. (16299617)
2005
29
Erupted complex odontoma: a case report and literature review. (15206258)
2004
30
Rare compound odontoma of the mandible in a 7-year-old child: case report. (14725505)
2003
31
Calcifying odontogenic cyst in infancy: report of case associated with compound odontoma. (7775688)
1995
32
Calcifying odontogenic cyst associated with compound odontoma: a study on undemineralized material. (7492892)
1995
33
Ameloblastic fibro-odontoma of the anterior maxilla. Report of a case. (8378043)
1993
34
An erupted odontoma: case report. (2760735)
1989
35
Melanin-pigment in complex odontoma. (3110324)
1987
36
Odontoma of a maxillary central incisor in a 10-year old black male. (2980418)
1986
37
Calcified odontoma. (275497)
1977
38
Compound odontoma in a 6-year-old girl; a case report. (266498)
1977
39
Odontoma containing ghost cells in the maxillary sinus. (4530972)
1974
40
Supernumerary tooth odontoma and dens in dente. (4524897)
1974
41
Compound composite odontoma. (4520183)
1973
42
Complex odontoma of the mandible. (4514708)
1973
43
Odontoma in an 11-year-old boy. A case report. (5249277)
1969
44
Complex composite odontoma--a case report. (5247630)
1968
45
A MELANOTIC AMELOBLASTIC ODONTOMA. (14237105)
1965
46
Complex-compound odontoma: report of case. (13976167)
1963
47
Ameloblastic odontoma. Report of a case. (14018994)
1963
48
Odontoma and impacted left mandibular cuspid. (14942970)
1952
49
Ameloblastic odontoma; report of case. (14851137)
1951
50
Cystic odontoma; report of a case. (20255326)
1947

Variations for Odontoma

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Expression for genes affiliated with Odontoma

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Search GEO for disease gene expression data for Odontoma.

Pathways for genes affiliated with Odontoma

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GO Terms for genes affiliated with Odontoma

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Cellular components related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1costamereGO:004303410.1KRT19, KRT8
2dystrophin-associated glycoprotein complexGO:001601010.1KRT19, KRT8
3keratin filamentGO:00450959.2KRT14, KRT18, KRT5, KRT8
4cell peripheryGO:00719448.5KRT14, KRT18, KRT19, KRT8, TUBB3
5intermediate filamentGO:00058827.5KRT14, KRT18, KRT19, KRT5, KRT8, NES
6extracellular exosomeGO:00700626.4KRT14, KRT18, KRT19, KRT5, KRT8, PCNA
7cytoplasmGO:00057376.3DSPP, KRT14, KRT18, KRT5, KRT8, NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cell differentiation involved in embryonic placenta developmentGO:006070610.3KRT19, KRT8
2hemidesmosome assemblyGO:003158110.1KRT14, KRT5
3sarcomere organizationGO:004521410.1KRT19, KRT8
4extrinsic apoptotic signaling pathwayGO:00971919.8KRT18, KRT8
5hepatocyte apoptotic processGO:00972849.3KRT18, KRT8
6viral processGO:00160328.0KRT18, KRT19, KRT8, VIM

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filament bindingGO:199025410.1KRT14, VIM
2structural molecule activityGO:00051988.3KRT18, KRT8, NES, VIM
3structural constituent of cytoskeletonGO:00052008.2KRT14, KRT19, KRT5, TUBB3, VIM
4scaffold protein bindingGO:00971108.1KRT18, KRT5, KRT8, VIM

Sources for Odontoma

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet