MCID: ODN006
MIFTS: 31

Odontoma malady

Rare diseases category

Summaries for Odontoma

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Sources:
66Wikipedia, 34MalaCards
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Wikipedia:66 An odontoma is a benign tumour of odontogenic origin (i.e. linked to tooth development). Specifically,... more...

MalaCards: Odontoma is related to adenoameloblastoma and fibroma. An important gene associated with Odontoma is LHX8 (LIM homeobox 8), and among its related pathways is Endometrial cancer. The compounds silver and formaldehyde have been mentioned in the context of this disorder. Affiliated tissues include bone and testes, and related mouse phenotype craniofacial.

Aliases & Classifications for Odontoma

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Sources:
44NIH Rare Diseases, 46Novoseek, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

odontoma 44 46 63


Related Diseases for Odontoma

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Odontoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 22)
idRelated DiseaseScoreTop Affiliating Genes
1adenoameloblastoma30.2DSPP, PCNA
2fibroma10.4
3odontoma dysphagia syndrome10.3
4sinusitis10.2
5pericoronitis10.1
6gingivitis10.1
7lipomatosis10.1
8encephalocraniocutaneous lipomatosis10.1
9prostate cancer10.0PCNA, DSPP
10sialolithiasis10.0
11actinomycosis10.0
12acute maxillary sinusitis10.0
13ludwig's angina10.0
14osteopetrosis10.0
15ataxia telangiectasia10.0
16amyloidosis10.0
17cellulitis10.0
18fibrosarcoma10.0
19neuropathy10.0
20dysphagia10.0
21odontomatosis - aortae esophagus stenosis10.0
22cleft palate10.0DSPP, LHX8

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to odontoma

Symptoms for Odontoma

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Drugs & Therapeutics for Odontoma

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Odontoma

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Genetic Tests for Odontoma

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Anatomical Context for Odontoma

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Sources:
34MalaCards
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MalaCards organs/tissues related to Odontoma:

34
Bone, Testes

Animal Models for Odontoma or affiliated genes

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Sources:
38MGI
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MGI Mouse Phenotypes related to Odontoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.5DSPP, LEF1, LHX8

Publications for Odontoma

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Sources:
53PubMed
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Articles related to Odontoma:

(show top 50)    (show all 447)
idTitleAuthorsYear
1
Complex composite odontoma with characteristic histology. (23840973)
2013
2
Compound odontoma in deciduous dentition. (23919208)
2013
3
Erupted composite odontoma associated with malformed teeth - unusual dental aberrations following maxillofacial trauma. (24399016)
2013
4
Aggressive ameloblastic fibro-odontoma assessment with CBCT and treatment. (23633233)
2013
5
Ameloblastic fibroma: a stage in the development of a hamartomatous odontoma or a true neoplasm? Critical analysis of 162 previously reported cases plus 10 new cases. (24055148)
2013
6
Compound odontoma. (22629054)
2012
7
Odontoma-associated tooth impaction: accurate diagnosis with simple methods? Case report and literature review. (22883320)
2012
8
Re: Pontes HA, Pontes FS, Lameira AG, Salim RA, Carvalho PL, GuimarALes DM, Pinto Ddos S Jr.: Report of four cases of ameloblastic fibro-odontoma in mandible and discussion of the literature about the treatment. J Craniomaxillofac Surg 40(2): e59-e63, 2012 Feb. Epub 2011 Apr 15. (22531299)
2012
9
Peripheral ameloblastic fibro-odontoma or peripheral developing complex odontoma: report of a case. (21689175)
2011
10
Hybrid odontogenic tumor with features of ameloblastic fibro-odontoma, calcifying odontogenic cyst, and adenomatoid odontogenic tumor: a case report and review of the literature. (20116726)
2010
11
Compound odontoma. (20533004)
2010
12
Importance of cone beam computed tomography for diagnosis of calcifying cystic odontogenic tumour associated to odontoma. Report of a case. (20038909)
2010
13
Multiple supernumerary teeth and odontoma in the maxilla: A case report. (22114378)
2010
14
Oral pathology quiz #69. Case number 2. Odontoma. (21341407)
2010
15
Oral Pathology Quiz #62. Case number 4. Ameloblastic fibro-odontoma. (19445048)
2009
16
The use of digital volume tomography in imaging an unusually large composite odontoma in the mandible. (19947141)
2009
17
Radiology quiz case. Complex odontoma of the maxillary sinus. (18559738)
2008
18
Surgical management of compound odontoma in a dog. (17691534)
2007
19
Odontomas in pediatric dentistry: report of two cases. (16491972)
2005
20
Surgical management of a large complex odontoma of the mandibular angle-ramus region through intra-oral buccal approach--A case report. (16380746)
2005
21
Surgical management of compound odontoma in two horses. (15552320)
2004
22
Rare compound odontoma of the mandible in a 7-year-old child: case report. (14725505)
2003
23
Calcifying odontogenic cyst in infancy: report of case associated with compound odontoma. (7775688)
1995
24
Calcifying odontogenic cyst associated with compound odontoma: a study on undemineralized material. (7492892)
1995
25
Case #10: Complex odontoma. (9534467)
1995
26
Bilateral complex odontoma in a Swiss (CD-1) male mouse. (8158975)
1994
27
Ameloblastic fibro-odontoma of the anterior maxilla. Report of a case. (8378043)
1993
28
Morphodifferentiation and histodifferentiation of the dental hard tissues in compound odontoma: a study of undemineralized material. (1403841)
1992
29
Ameloblastic odontoma (odonto-ameloblastoma). (2011364)
1991
30
An erupted odontoma: case report. (2760735)
1989
31
Ameloblastic fibro-odontoma. Case report. (2705938)
1989
32
Compound composite odontoma--a case report. (3473134)
1986
33
Odontoma of a maxillary central incisor in a 10-year old black male. (2980418)
1986
34
Compound odontoma--a case report. (3458819)
1986
35
Cholesterol granuloma embedded in an odontoma of the maxilla. (6585505)
1984
36
Odontoma in the subcondylar region. (298840)
1979
37
Transantral odontoma. A case report. (282542)
1978
38
Calcified odontoma. (275497)
1977
39
Compound odontoma in a 6-year-old girl; a case report. (266498)
1977
40
Ameloblastic odontoma in rats induced by N-butylnitrosourea. (1181232)
1975
41
Odontoma containing ghost cells in the maxillary sinus. (4530972)
1974
42
Supernumerary tooth odontoma and dens in dente. (4524897)
1974
43
Compound composite odontoma. (4520183)
1973
44
A midpalatal compound odontoma in an infant. (5263262)
1970
45
Radiographic survey of a composite odontoma growth during five years. Report of a case. (5259675)
1969
46
A MELANOTIC AMELOBLASTIC ODONTOMA. (14237105)
1965
47
Complex-compound odontoma: report of case. (13976167)
1963
48
Ameloblastic odontoma. Report of a case. (14018994)
1963
49
Odontoma of maxilla; report of case. (14825010)
1951
50
Cystic odontoma; report of a case. (20255326)
1947

Variations for Odontoma

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Expression for genes affiliated with Odontoma

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for genes affiliated with Odontoma

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Sources:
51PathCards, 31KEGG, 61Thomson Reuters
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Pathways related to Odontoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Signal transduction PTEN pathway61
9.1PCNA, LEF1

Compounds for genes affiliated with Odontoma

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Sources:
46Novoseek, 25HMDB, 12DrugBank, 52PharmGKB, 62Tocris Bioscience
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Compounds related to Odontoma according to GeneCards/GeneDecks:

(show all 11)
idCompoundScoreTop Affiliating Genes
1silver469.6PCNA, DSPP
2formaldehyde46 2510.5DSPP, PCNA
3carbon469.5PCNA, DSPP
4glycerol46 25 1211.5PCNA, DSPP
5epinephrine46 25 1211.4DSPP, PCNA
6ascorbic acid46 2510.4PCNA, DSPP
7paraffin469.3PCNA, DSPP
8aspartate469.3PCNA, DSPP
9lactate469.2DSPP, PCNA
10cisplatin46 52 62 1211.8PCNA, LEF1
11alanine468.7PCNA, DSPP, LEF1

GO Terms for genes affiliated with Odontoma

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Sources:
17Gene Ontology
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Biological processes related to Odontoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1odontogenesis of dentin-containing toothGO:0424759.1LEF1, LHX8

Molecular functions related to Odontoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1sequence-specific DNA bindingGO:0435659.1LEF1, LHX8

Products for genes affiliated with Odontoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Odontoma

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet