MCID: ODN006
MIFTS: 34

Odontoma malady

Category: Rare diseases

Aliases & Classifications for Odontoma

About this section

Aliases & Descriptions for Odontoma:

Name: Odontoma 48 27 50 68

Classifications:



Summaries for Odontoma

About this section
Wikipedia:71 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

MalaCards based summary: Odontoma is related to odontoma-dysphagia syndrome and calcifying epithelial odontogenic tumor. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways are Signaling mediated by p38-alpha and p38-beta and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include bone and testes, and related mouse phenotypes are Decreased shRNA abundance (Z-score < -2) and digestive/alimentary.

Related Diseases for Odontoma

About this section

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 114)
idRelated DiseaseScoreTop Affiliating Genes
1odontoma-dysphagia syndrome12.2
2calcifying epithelial odontogenic tumor10.8
3familial periodic paralysis10.5KRT5, KRT8
4mental retardation, autosomal recessive 4910.5KRT14, KRT8
5pachyonychia congenita 310.5KRT14, KRT5
6dowling-degos disease 110.5KRT14, KRT5
7quinquaud's decalvans folliculitis10.5KRT14, KRT5
8epidermolytic acanthoma10.5KRT14, KRT5
9sed congenita10.5KRT14, KRT5
10male reproductive organ cancer10.5KRT14, KRT8
11hemoglobin d disease10.5KRT14, KRT5
12benign intermediate mesothelioma10.5KRT14, KRT5
13gastric squamous cell carcinoma10.5KRT14, KRT5
14female breast lower-inner quadrant cancer10.5KRT14, KRT5
15breast neuroendocrine neoplasm10.5KRT14, KRT5
16mast-cell sarcoma10.5KRT5, KRT8
17darier disease10.5KRT14, KRT5
18epidermolysis bullosa simplex-mp10.5KRT14, KRT5
19prostatic acinar adenocarcinoma10.5KRT14, KRT8
20anal squamous cell carcinoma10.5KRT14, KRT8
21gilbert syndrome10.5KRT14, KRT5
22epidermal nevus vitamin d resistant rickets10.4KRT8, VIM
23amelogenesis imperfecta local hypoplastic10.4KRT14, VIM
24bronchiolo-alveolar adenocarcinoma10.4KRT5, KRT8
25sclerosing liposarcoma10.4KRT8, VIM
26connective tissue benign neoplasm10.4KRT14, KRT5
27papillary adenoma10.4KRT14, KRT5
28lymphocytic vasculitis10.4PCNA, VIM
29ovarian mucinous adenocarcinoma10.4PCNA, VIM
30bartholin's gland benign neoplasm10.4KRT14, VIM
31vulvar alveolar soft part sarcoma10.4KRT14, VIM
32eccrine papillary adenoma10.4KRT14, VIM
33colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas10.4KRT14, KRT5
34pleomorphic carcinoma10.4KRT14, KRT5
35hyperinsulinemic hypoglycemia, familial, 410.4KRT8, VIM
36malignant cystic nephroma10.4KRT5, VIM
37ovarian cystadenocarcinoma10.4PCNA, VIM
38nerve fibre bundle defect10.4KRT5, KRT8
39pediatric meningioma10.4KRT8, VIM
40short stature-deafness-neutrophil dysfunction-dysmorphism syndrome10.3KRT18, KRT8
41hypotrichosis 1310.3KRT18, KRT8
42ductal carcinoma in situ10.3KRT14, KRT5
43centrotemporal epilepsy10.3LHX8, PCNA
44primary syphilis10.3TUBB3, VIM
45vulval paget's disease10.3KRT14, KRT5, KRT8
46sm-ahnmd10.3NES, VIM
47novak syndrome10.3KRT5, VIM
48ependymoblastoma10.2NES, VIM
49bone squamous cell carcinoma10.2KRT14, KRT8
50trochlear nerve neoplasm10.2KRT5, NES

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to odontoma

Symptoms & Phenotypes for Odontoma

About this section

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00366-A-589.7KRT18, KRT5, KRT8

MGI Mouse Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.4KRT14, KRT19, KRT5, KRT8, LHX8
2MP:00107686.4KRT14, KRT18, KRT19, KRT5, KRT8, LHX8

Drugs & Therapeutics for Odontoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

About this section

Genetic tests related to Odontoma:

id Genetic test Affiliating Genes
1 Odontoma27

Anatomical Context for Odontoma

About this section

MalaCards organs/tissues related to Odontoma:

36
Bone, Testes

Publications for Odontoma

About this section

Articles related to Odontoma:

(show top 50)    (show all 511)
idTitleAuthorsYear
1
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. (27563600)
2016
2
Diagnostic Discussion. Ameloblastic fibro-odontoma. (27024969)
2016
3
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. (26825866)
2016
4
Archegonous Cystic Odontoma Is Not Necessarily Primordial. (26843411)
2016
5
Dentigerous cyst arising from a complex odontoma: an unusual presentation. (27090549)
2016
6
Compound odontoma associated with impacted maxillary central incisor dictates a need to be vigilant to canine eruption pattern: A 2-year follow-up. (27307685)
2016
7
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. (28025437)
2016
8
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. (27514999)
2016
9
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. (26981293)
2016
10
Extensive Mandibular Ameloblastic Fibro-Odontoma. (27428924)
2016
11
Management of a massive compound odontoma in a 9-year child. (27630512)
2016
12
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. (27307963)
2016
13
Odontoma in a 255-Million-Year-Old Mammalian Forebear. (27930769)
2016
14
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). (26709130)
2016
15
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. (27790601)
2016
16
Multiple complex odontoma of the maxilla and mandible-reply. (26972543)
2016
17
Complex Odontoma: A Case Report with Micro-Computed Tomography Findings. (27293913)
2016
18
Dilated odontoma: A report of two cases from a radiological perspective. (27041914)
2016
19
Management of a Compound Odontoma in the Primary Dentition. (27620522)
2016
20
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? (27098720)
2016
21
Response to the Letter Entitled "Archegonous Cystic Odontoma Is Not Necessarily Primordial" by Ide et al. (26857026)
2016
22
An Erupted Dilated Odontoma: A Rare Presentation. (26989523)
2016
23
Compound composite odontoma. (27194882)
2016
24
Cystic Odontoma in a Patient with Hodgkin's Lymphoma. (26618008)
2015
25
Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma. (26289508)
2015
26
Ameloblastic fibro-odontoma. (26045519)
2015
27
Discussion: An alternative treatment option for a bony defect from large odontoma using recycled demineralization at chairside. (25922825)
2015
28
Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review. (26612404)
2015
29
Surgical Management of Compound Odontoma Associated with Unerupted Tooth. (26199762)
2015
30
Unusually large erupted complex odontoma: A rare case report. (25793183)
2015
31
Compound Odontoma in a Pediatric Patient With Aspects Similar to Complex Odontoma. (26080222)
2015
32
An alternative treatment option for a bony defect from large odontoma using recycled demineralization at chairside. (25922824)
2015
33
Primordial Odontogenic Cyst with Induction Phenomenon (Zonal Fibroblastic Hypercellularity) and Dentinoid Material Versus Archegonous Cystic Odontoma: You Choose! (26156422)
2015
34
Bilateral coronoid hypoplasia and complex odontoma: a rare concurrence of developmental pathology and odontogenic tumour of the mandible. (26464410)
2015
35
Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management. (25848139)
2015
36
Impacted permanent incisors associated with compound odontoma. (25583937)
2015
37
Giant complex odontoma in maxillary sinus. (26389051)
2015
38
Multiple complex odontoma of the maxilla and the mandible. (25921711)
2015
39
Ectopic compound odontoma in the buccal mucosa: report of a rare case. (25810930)
2015
40
Super odontoma - a destructive swarm entity. (25954721)
2015
41
Erupted complex odontoma of the posterior maxilla: A rarity. (26604611)
2015
42
Activated WNT signaling in postnatal SOX2-positive dental stem cells can drive odontoma formation. (26411543)
2015
43
'Dilated odontoma': an incidental finding. (26452745)
2015
44
Post-Odontoma autotransplantation of an impacted tooth: A case report. (26258027)
2015
45
Ameloblastic fibro-odontoma. (25437658)
2014
46
Compound composite odontoma and its management. (25587458)
2014
47
Pathology in practice. Compound odontoma in a horse. (24479454)
2014
48
Histopathological insight of complex odontoma associated with a dentigerous cyst. (24488658)
2014
49
Large complex odontoma of mandible in a young boy: a rare and unusual case report. (24818029)
2014
50
Management of large erupting complex odontoma in maxilla. (25580339)
2014

Variations for Odontoma

About this section

Expression for genes affiliated with Odontoma

About this section
Search GEO for disease gene expression data for Odontoma.

Pathways for genes affiliated with Odontoma

About this section

GO Terms for genes affiliated with Odontoma

About this section

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1costamereGO:004303410.5KRT19, KRT8
2dystrophin-associated glycoprotein complexGO:001601010.4KRT19, KRT8
3cell peripheryGO:00719448.8KRT14, KRT18, KRT19, KRT8, TUBB3
4keratin filamentGO:00450958.6KRT14, KRT18, KRT5, KRT8
5intermediate filamentGO:00058827.4KRT14, KRT18, KRT19, KRT5, KRT8, NES
6extracellular exosomeGO:00700627.3KRT14, KRT18, KRT19, KRT5, KRT8, PCNA
7cytoplasmGO:00057377.1DSPP, KRT14, KRT18, KRT5, KRT8, NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hemidesmosome assemblyGO:003158110.4KRT14, KRT5
2cell differentiation involved in embryonic placenta developmentGO:006070610.3KRT19, KRT8
3sarcomere organizationGO:004521410.3KRT19, KRT8
4extrinsic apoptotic signaling pathwayGO:009719110.0KRT18, KRT8
5hepatocyte apoptotic processGO:009728410.0KRT18, KRT8
6viral processGO:00160328.3KRT18, KRT19, KRT8, VIM

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1keratin filament bindingGO:199025410.2KRT14, VIM
2scaffold protein bindingGO:00971109.0KRT18, KRT5, KRT8, VIM
3structural constituent of cytoskeletonGO:00052008.8KRT14, KRT19, KRT5, TUBB3, VIM
4structural molecule activityGO:00051988.2KRT18, KRT8, NES, VIM

Sources for Odontoma

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet