Aliases & Classifications for Odontoma

MalaCards integrated aliases for Odontoma:

Name: Odontoma 49 28 51 69

Classifications:



External Ids:

UMLS 69 C0028882

Summaries for Odontoma

MalaCards based summary : Odontoma is related to ameloblastoma and odontoma-dysphagia syndrome. An important gene associated with Odontoma is LHX8 (LIM Homeobox 8), and among its related pathways/superpathways are Keratinization and Cytoskeletal Signaling. Affiliated tissues include bone and testes, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Wikipedia : 72 An odontoma (also termed odontome) is a benign tumour of odontogenic origin (i.e. linked to tooth... more...

Related Diseases for Odontoma

Diseases related to Odontoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 123)
# Related Disease Score Top Affiliating Genes
1 ameloblastoma 30.0 KRT14 KRT18 KRT8 PCNA
2 odontoma-dysphagia syndrome 12.4
3 encephalocraniocutaneous lipomatosis 11.2
4 dens evaginatus 10.9
5 calcifying epithelial odontogenic tumor 10.9
6 brooke-spiegler syndrome 10.5 KRT14 KRT8
7 prostate squamous cell carcinoma 10.4 KRT5 KRT8
8 epidermolysis bullosa simplex, autosomal recessive 1 10.4 KRT14 KRT5
9 benign breast adenomyoepithelioma 10.4 KRT14 KRT5
10 epidermolysis bullosa simplex, localized 10.4 KRT14 KRT5
11 lichen planopilaris 10.4 KRT14 KRT5
12 epidermolysis bullosa simplex, generalized 10.4 KRT14 KRT5
13 large cell acanthoma 10.4 KRT14 KRT5
14 epidermolysis bullosa simplex with mottled pigmentation 10.4 KRT14 KRT5
15 breast adenomyoepithelioma 10.4 KRT14 KRT5
16 breast myoepithelial neoplasm 10.4 KRT14 KRT5
17 breast squamous cell carcinoma 10.4 KRT14 KRT5
18 basaloid squamous cell carcinoma 10.4 KRT14 KRT8
19 atypical choroid plexus papilloma 10.4 KRT5 KRT8
20 vesiculobullous skin disease 10.4 KRT14 KRT5
21 nasal cavity squamous cell carcinoma 10.4 KRT5 KRT8
22 epidermolysis bullosa simplex, dowling-meara type 10.4 KRT14 KRT5
23 breast secretory carcinoma 10.4 KRT5 KRT8
24 ameloblastic carcinoma 10.4 KRT14 VIM
25 lymphangiomatosis 10.4 PCNA VIM
26 integumentary system benign neoplasm 10.4 KRT14 KRT5
27 leukoplakia 10.4 KRT8 PCNA
28 long-chain 3-hydroxyacyl-coa dehydrogenase deficiency 10.4 KRT8 VIM
29 pleomorphic liposarcoma 10.4 KRT8 VIM
30 lipid-rich carcinoma 10.3 KRT14 KRT5
31 ovarian mucinous cystadenocarcinoma 10.3 PCNA VIM
32 peritoneum cancer 10.3 KRT5 TUBB3
33 fibrolamellar carcinoma 10.3 KRT8 VIM
34 melanotic neuroectodermal tumor 10.3 PCNA VIM
35 breast metaplastic carcinoma 10.3 KRT14 KRT5
36 papillary adenoma 10.3 KRT5 VIM
37 spiradenoma 10.3 KRT14 VIM
38 mucinous cystadenocarcinoma 10.3 PCNA VIM
39 cavernous hemangioma 10.3 KRT14 VIM
40 neurenteric cyst 10.3 KRT18 KRT8
41 chondroid chordoma 10.3 TUBB3 VIM
42 cryptogenic cirrhosis 10.2 KRT18 KRT8
43 breast fibroadenoma 10.2 KRT14 KRT8
44 hidradenocarcinoma 10.2 KRT5 VIM
45 apocrine sweat gland neoplasm 10.2 KRT14 KRT5 KRT8
46 secretory meningioma 10.2 KRT8 VIM
47 pre-malignant neoplasm 10.2 KRT14 KRT5 KRT8
48 pleomorphic carcinoma 10.2 KRT18 KRT8
49 sweat gland cancer 10.2 KRT14 KRT5 KRT8
50 ductal carcinoma in situ 10.2 KRT14 KRT5 KRT8

Graphical network of the top 20 diseases related to Odontoma:



Diseases related to Odontoma

Symptoms & Phenotypes for Odontoma

GenomeRNAi Phenotypes related to Odontoma according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-153 9.47 KRT5
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-154 9.47 KRT18
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-17 9.47 KRT18 KRT5
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-180 9.47 KRT5 KRT8
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-200 9.47 KRT5
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-33 9.47 KRT18
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-40 9.47 KRT8
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-71 9.47 KRT18 KRT5 KRT8
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-84 9.47 KRT18
10 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.47 KRT5

MGI Mouse Phenotypes related to Odontoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 mortality/aging MP:0010768 9.28 KRT14 KRT18 KRT19 KRT5 KRT8 LHX8

Drugs & Therapeutics for Odontoma

Search Clinical Trials , NIH Clinical Center for Odontoma

Genetic Tests for Odontoma

Genetic tests related to Odontoma:

# Genetic test Affiliating Genes
1 Odontoma 28

Anatomical Context for Odontoma

MalaCards organs/tissues related to Odontoma:

38
Bone, Testes

Publications for Odontoma

Articles related to Odontoma:

(show top 50) (show all 529)
# Title Authors Year
1
Ameloblastic Fibrodentinoma and Ameloblastic Fibro-Odontoma: An Updated Systematic Review of Cases Reported in the Literature. ( 28153756 )
2017
2
Ameloblastic Fibro-odontoma with a Predominant Radiopaque Component. ( 29264304 )
2017
3
Association Between Odontoma and Impacted Teeth. ( 28468159 )
2017
4
Metachronous ameloblastic fibro-odontoma and dentigerous cyst in the posterior mandible. ( 29099370 )
2017
5
Giant Complex Odontoma of Mandible: A Spectacular Case Report. ( 28839489 )
2017
6
An unusual foreign object mimicking an odontoma in a patient with cleft alveolus: a case report. ( 28946895 )
2017
7
Removal of Compound Odontoma With Piezosurgery Technique. ( 28278140 )
2017
8
Spontaneous Peripheral Ameloblastic Odontoma in a Male Sprague-Dawley Rat. ( 28503263 )
2017
9
Compound Odontoma in Anterior Mandible-A Case Report. ( 28814937 )
2017
10
Ameloblastic Fibro-Odontoma of the Maxilla in a Pierre-Robin Sequence Patient. ( 28557592 )
2017
11
Association Between Odontoma and Impacted Teeth. ( 28106699 )
2017
12
A rare case report of an adenomatoid odontogenic tumor associated with odontoma in the maxilla. ( 28863377 )
2017
13
Autotransplantation of Odontoma-Associated Impacted Teeth-A Treatment Strategy for Satisfying Immediate Esthetic Demands: A Case Report. ( 28460214 )
2017
14
Ameloblastic Fibro-Odontoma in a 7-Month-Old Infant: A Case Report. ( 29034280 )
2017
15
Clinical, pathological, and genetic evaluations of Chinese patient with otodental syndrome and multiple complex odontoma: Case report. ( 28151902 )
2017
16
Immediate Dental Implant Placement After Removal of Complex Odontoma. ( 28922246 )
2017
17
Surgical Access to a Complex Composite Odontoma via Sagittal Split Osteotomy of the Mandible. ( 29441249 )
2017
18
Management of a massive compound odontoma in a 9-year child. ( 27630512 )
2016
19
Ameloblastic fibroodontoma or complex odontoma: Two faces of the same coin. ( 28163488 )
2016
20
Archegonous Cystic Odontoma Is Not Necessarily Primordial. ( 26843411 )
2016
21
Multiple complex odontoma of the maxilla and mandible-reply. ( 26972543 )
2016
22
Complex Odontoma: A Case Report with Micro-Computed Tomography Findings. ( 27293913 )
2016
23
Diagnostic Discussion. Ameloblastic fibro-odontoma. ( 27024969 )
2016
24
Extensive Mandibular Ameloblastic Fibro-Odontoma. ( 27428924 )
2016
25
Ameloblastic Fibro-Odontoma in a 4-Year-Old Boy. ( 27307963 )
2016
26
Diverse calcification patterns of ameloblastic fibro-odontoma on radiographic examination. ( 28025437 )
2016
27
Dilated odontoma: A report of two cases from a radiological perspective. ( 27041914 )
2016
28
Response to the Letter Entitled "Archegonous Cystic Odontoma Is Not Necessarily Primordial" by Ide et al. ( 26857026 )
2016
29
Lateral Approach for Excision of Maxillary Incisor Pseudo-Odontoma in Prairie Dogs (Cynomys ludovicianus). ( 26709130 )
2016
30
Odontoma in a 255-Million-Year-Old Mammalian Forebear. ( 27930769 )
2016
31
Large ameloblastic fibro-odontoma in a 7-year-old girl with analysis of 108 cases. ( 27563600 )
2016
32
Erupted Large Anterior Maxillary Complex Odontoma: A Rare Dental Hamartoma. ( 27790601 )
2016
33
Compound odontoma associated with impacted maxillary central incisor dictates a need to be vigilant to canine eruption pattern: A 2-year follow-up. ( 27307685 )
2016
34
Campylorrhinus lateralis, Bilateral microphthalmia and odontoma temporalis in an Oldenburg Foal. ( 26825866 )
2016
35
Long-term culture of human odontoma-derived cells with a Rho kinase inhibitor. ( 27514999 )
2016
36
Compound composite odontoma. ( 27194882 )
2016
37
Peripheral Developing Odontoma or Peripheral Ameloblastic Fibroodontoma: A Rare Challenging Case. ( 26981293 )
2016
38
Peripheral Tumor with Osteodentin and Cementum-like Material in an Infant: Odontogenic Hamartoma or Odontoma? ( 27098720 )
2016
39
Management of a Compound Odontoma in the Primary Dentition. ( 27620522 )
2016
40
Dentigerous cyst arising from a complex odontoma: an unusual presentation. ( 27090549 )
2016
41
An Erupted Dilated Odontoma: A Rare Presentation. ( 26989523 )
2016
42
Impacted permanent incisors associated with compound odontoma. ( 25583937 )
2015
43
Extensive complex odontoma in the maxillary sinus pushing 3rd molar near the orbital floor causing transient diplopia and chronic sinusitis: a rare presentation and surgical management. ( 25848139 )
2015
44
Cystic Odontoma in a Patient with Hodgkin's Lymphoma. ( 26618008 )
2015
45
Complex and compound odontomas: Analysis of 69 cases and a rare case of erupted compound odontoma. ( 26289508 )
2015
46
Unusually large erupted complex odontoma: A rare case report. ( 25793183 )
2015
47
Giant complex odontoma in maxillary sinus. ( 26389051 )
2015
48
Compound Odontoma in a Pediatric Patient With Aspects Similar to Complex Odontoma. ( 26080222 )
2015
49
Bilateral coronoid hypoplasia and complex odontoma: a rare concurrence of developmental pathology and odontogenic tumour of the mandible. ( 26464410 )
2015
50
Clinical parameter of odontoma with special emphasis on treatment of impacted teeth-a retrospective multicentre study and literature review. ( 26612404 )
2015

Variations for Odontoma

Expression for Odontoma

Search GEO for disease gene expression data for Odontoma.

Pathways for Odontoma

GO Terms for Odontoma

Cellular components related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.86 KRT14 KRT18 KRT19 KRT5 KRT8 PCNA
2 keratin filament GO:0045095 9.46 KRT14 KRT18 KRT5 KRT8
3 apicolateral plasma membrane GO:0016327 9.4 KRT19 KRT8
4 costamere GO:0043034 9.37 KRT19 KRT8
5 cell periphery GO:0071944 9.35 KRT14 KRT18 KRT19 KRT8 TUBB3
6 dystrophin-associated glycoprotein complex GO:0016010 9.32 KRT19 KRT8
7 intermediate filament GO:0005882 9.17 KRT14 KRT18 KRT19 KRT5 KRT8 NES

Biological processes related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 9.67 KRT18 KRT19 KRT8 VIM
2 extrinsic apoptotic signaling pathway GO:0097191 9.43 KRT18 KRT8
3 sarcomere organization GO:0045214 9.4 KRT19 KRT8
4 keratinization GO:0031424 9.35 KRT14 KRT18 KRT19 KRT5 KRT8
5 hemidesmosome assembly GO:0031581 9.32 KRT14 KRT5
6 hepatocyte apoptotic process GO:0097284 9.26 KRT18 KRT8
7 cell differentiation involved in embryonic placenta development GO:0060706 9.16 KRT19 KRT8
8 cornification GO:0070268 9.02 KRT14 KRT18 KRT19 KRT5 KRT8

Molecular functions related to Odontoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.56 KRT18 KRT8 NES VIM
2 scaffold protein binding GO:0097110 9.26 KRT18 KRT5 KRT8 VIM
3 keratin filament binding GO:1990254 9.16 KRT14 VIM
4 structural constituent of cytoskeleton GO:0005200 9.02 KRT14 KRT19 KRT5 TUBB3 VIM

Sources for Odontoma

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16 ExPASy
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67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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