MCID: OLG006
MIFTS: 44

Oligoastrocytoma malady

Rare diseases, Neuronal diseases, Cancer diseases categories

Aliases & Classifications for Oligoastrocytoma

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Sources:
60UMLS, 41NIH Rare Diseases, 47Orphanet, 22GTR, 43Novoseek, 61UMLS via Orphanet
See all sources

Oligoastrocytoma, Aliases & Descriptions:

Name: Oligoastrocytoma 41 47 22
Mixed Oligoastrocytoma 41 47 60
Moa 41 47
 
Mixed Oligodendroglioma-Astrocytoma 60
Oligoastrocytoma Mixed 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Neuronal diseases


External Ids:

Orphanet47 251656
UMLS via Orphanet61 C0280793

Summaries for Oligoastrocytoma

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NIH Rare Diseases:41 Oligoastrocytoma is a brain tumor that forms when two types of cells in the brain, called oligodendrocytes and astrocytes, rapidly increase in number to form a mass.  these brain cells are known as glial cells, which normally protect and support nerve cells in the brain.  because an oligoastrocytoma is made up of a combination of two cell types, it is known as a mixed glioma.  oligoastrocytomas usually occur in a part of the brain called the cerebrum and are diagnosed in adults between the ages of 30 and 50.  the exact cause of this condition is unknown. last updated: 10/5/2012

MalaCards based summary: Oligoastrocytoma, also known as mixed oligoastrocytoma, is related to oligodendroglioma and anaplastic oligodendroglioma. An important gene associated with Oligoastrocytoma is IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), and among its related pathways are Angiogenesis and Cytoskeleton remodeling Role of PDGFs in cell migration. The compounds n-ethyl-n-nitrosourea and sarcnu have been mentioned in the context of this disorder. Affiliated tissues include brain, bone marrow and bone, and related mouse phenotypes are no phenotypic analysis and muscle.

Wikipedia:63 Oligoastrocytomas are a subset of brain tumors that present with an appearance of mixed glial cell... more...

Related Diseases for Oligoastrocytoma

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Diseases related to Oligoastrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 65)
idRelated DiseaseScoreTop Affiliating Genes
1oligodendroglioma31.6GFAP, MGMT
2anaplastic oligodendroglioma31.1MGMT, GFAP, PDGFRA
3mixed glioma30.5PDGFRA, GFAP
4astrocytoma29.7MGMT, IDH1, GFAP, TP53, NES, CXCR4
5leukemia28.8MGMT, IDH2, ID4, IDH1, TP53, NES
6anaplastic oligoastrocytoma10.7
7gliosarcoma10.5GFAP
8subependymal giant cell astrocytoma10.5GFAP
9giant cell glioblastoma10.5GFAP
10gliomatosis cerebri10.5GFAP
11anaplastic ependymoma10.5GFAP
12gemistocytic astrocytoma10.5GFAP
13pineoblastoma10.5GFAP
14ganglioglioma10.5GFAP
15chondroma10.4PDGFRA
16choroid plexus papilloma10.4TP53, GFAP
17hemangioblastoma10.4GFAP, NES
18meningioma, familial10.3GFAP, PDGFB
19retinal detachment10.3GFAP, PDGFB
20interval angle-closure glaucoma10.2IDH2, IDH1
21chordoma10.2GFAP, PDGFRA
22malignant peripheral nerve sheath tumor10.2PDGFRA, NES
23d-2-hydroxyglutaric aciduria10.2IDH2, IDH1
24intraductal papilloma10.2IDH2, IDH1
25barrett esophagus/esophageal adenocarcinoma10.2MGMT, TP53
26teratoma10.2NES, GFAP
27desmoid disease, hereditary10.2PDGFRA, PDGFB
28neurilemmoma10.2GFAP, NES, PDGFRA
29leiomyosarcoma10.2PDGFRA, NES, TP53
30lung benign neoplasm10.2MGMT, TP53, PDGFB
31pilocytic astrocytoma10.1MGMT, IDH1, GFAP, NES
32brain cancer10.1NES, TP53, GFAP, IDH1
33paraganglioma10.1GFAP, IDH2
34ependymoma10.1MGMT, GFAP, NES, PDGFRA
35small cell cancer of the lung, somatic10.1MGMT, TP53, PDGFRA
36arteriosclerosis10.1PDGFRA, PDGFB
37squamous cell carcinoma, head and neck10.1CXCR4, TP53, MGMT
38stomach cancer10.0PDGFB, TP53, MGMT
39cysticercosis10.0
40cerebritis10.0
41dermatomyositis10.0
42dystonia10.0
43focal dystonia10.0
44lymphoblastic leukemia10.0
45myeloid leukemia10.0
46myoclonus10.0
47gastrointestinal stromal tumor10.0PDGFRA, NES
48rhabdomyosarcoma10.0TP53, NES, PDGFRA, PDGFB
49sarcoma10.0TP53, NES, PDGFRA, PDGFB
50adenoma10.0CXCR4, NES, TP53, MGMT

Graphical network of the top 20 diseases related to Oligoastrocytoma:



Diseases related to oligoastrocytoma

Symptoms for Oligoastrocytoma

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Drugs & Therapeutics for Oligoastrocytoma

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Drug clinical trials:

Search ClinicalTrials for Oligoastrocytoma

Search NIH Clinical Center for Oligoastrocytoma

Genetic Tests for Oligoastrocytoma

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Genetic tests related to Oligoastrocytoma:

id Genetic test Affiliating Genes
1 Oligoastrocytoma22

Anatomical Context for Oligoastrocytoma

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MalaCards organs/tissues related to Oligoastrocytoma:

31
Brain, Bone marrow, Bone, Spinal cord, Myeloid

Animal Models for Oligoastrocytoma or affiliated genes

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MGI Mouse Phenotypes related to Oligoastrocytoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00030128.6MGMT, TP53, FABP7, PDGFRA, PDGFB
2MP:00053698.5PDGFB, PDGFRA, CXCR4, TP53, GFAP
3MP:00053888.2TP53, CIC, CXCR4, PDGFRA, PDGFB
4MP:00053867.9ID4, GFAP, TP53, CIC, NES, FABP7
5MP:00053767.6MGMT, IDH1, GFAP, TP53, FABP7, CXCR4
6MP:00053787.4ID4, GFAP, TP53, CIC, NES, CXCR4
7MP:00107687.2MGMT, ID4, GFAP, TP53, CIC, NES
8MP:00036317.2PDGFB, ID4, GFAP, TP53, CIC, NES

Publications for Oligoastrocytoma

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Articles related to Oligoastrocytoma:

(show top 50)    (show all 69)
idTitleAuthorsYear
1
Anaplastic oligoastrocytoma: is molecular stratification based on 1p/19q status alone appropriate? (25555564)
2015
2
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors. (24162809)
2014
3
Clinical discussion of the management of anaplastic oligodendroglioma/oligoastrocytoma (both codeleted and nondeleted). (24812135)
2014
4
Pattern of care of anaplastic oligodendroglioma and oligoastrocytoma in a Korean population: the Korean radiation oncology group study 13-12. (25391968)
2014
5
Mixed Glioma (Oligoastrocytoma) in the Brain ofA an African Hedgehog (Atelerix albiventris). (25172052)
2014
6
Farewell to oligoastrocytoma: response to letters. (25381649)
2014
7
1p/19q codeletion and IDH1/2 mutation identified a subtype of anaplastic oligoastrocytomas with prognosis as favorable as anaplastic oligodendrogliomas. (23486687)
2013
8
Infratentorial low-grade oligoastrocytoma with aggressive clinical behavior in an adult: a case report with genetic characterization. (22752622)
2013
9
Experiential auditory hallucinations due to chronic epileptic discharges after radiotherapy for oligoastrocytoma. (23774105)
2013
10
Cerebellar low-grade oligoastrocytoma presenting with subarachnoid haemorrhage. (22665014)
2012
11
CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas. (22588899)
2012
12
Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. (21069360)
2011
13
Preoperative chemotherapy for infiltrative low-grade oligoastrocytoma: a useful strategy to maximize surgical resection -case report-. (20505301)
2010
14
Intrathecal liposomal cytarabine in combination with temozolomide in low-grade oligoastrocytoma with leptomeningeal dissemination. (19876600)
2010
15
Novel genomic alterations and mechanisms associated with tumor progression in oligodendroglioma and mixed oligoastrocytoma. (19225409)
2009
16
Oligoastrocytoma of the brain in a hooded crane (Grus monacha). (19261644)
2009
17
A multicenter cohort study of dose-dense temozolomide (21 of 28 days) for the treatment of recurrent anaplastic astrocytoma or oligoastrocytoma. (18317968)
2008
18
Isolation and characterization of stem cell-like precursor cells from primary human anaplastic oligoastrocytoma. (17660801)
2007
19
Prognosis in patients with anaplastic oligoastrocytoma is associated with histologic grade. (17431544)
2007
20
Oligoastrocytoma presenting with intractable epilepsy. (17884756)
2007
21
Intradural extramedullary spinal spread of oligoastrocytoma. (17582770)
2007
22
Malignant transformation of oligoastrocytoma: a case report. (18095133)
2007
23
Qualitative and quantitative analysis of cytologic assessment of astrocytoma, oligodendroglioma and oligoastrocytoma. (18077983)
2007
24
Anaplastic oligodendroglioma and oligoastrocytoma. (17964027)
2007
25
Genetically distinct astrocytic and oligodendroglial components in oligoastrocytomas. (17031656)
2007
26
Anaplastic oligoastrocytoma: previous treatment as a possible cause in a child with acute lymphoblastic leukemia. (17043901)
2007
27
Paroxysmal focal dystonia with sensory symptoms secondary to cortical oligoastrocytoma. (16598615)
2006
28
Prognostic value of CXCL12 expression in 40 low-grade oligodendrogliomas and oligoastrocytomas. (16760646)
2006
29
Positive reaction for cysticercosis and multicentric anaplastic oligoastrocytoma. (15778869)
2006
30
Comparative genetic analysis of metachronous anaplastic oligoastrocytomas with extended recurrence-free interval. (15925987)
2005
31
Fractionated stereotactic radiation therapy in the management of primary oligodendroglioma and oligoastrocytoma. (15936562)
2005
32
Id4 and FABP7 are preferentially expressed in cells with astrocytic features in oligodendrogliomas and oligoastrocytomas. (16018821)
2005
33
Efficacy and feasibility of standard procarbazine, lomustine, and vincristine chemotherapy in anaplastic oligodendroglioma and oligoastrocytoma recurrent after radiotherapy. A Phase II study. (15372474)
2004
34
Combined treatment modality for anaplastic oligodendroglioma and oligoastrocytoma: a 10-year update of a phase II study. (15145170)
2004
35
Prognostic impact of TP53 mutation status for adult patients with supratentorial World Health Organization Grade II astrocytoma or oligoastrocytoma: a long-term analysis. (15329912)
2004
36
Low-grade glioma: supratentorial astrocytoma, oligodendroglioma, and oligoastrocytoma in adults. (15102347)
2004
37
Cytoplasmic crystalline inclusions in a anaplastic oligoastrocytoma. (15471429)
2004
38
Primary spinal oligoastrocytoma: a case report. (14706386)
2004
39
Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. (12525516)
2003
40
Carboplatin and teniposide as third-line chemotherapy in patients with recurrent oligodendroglioma or oligoastrocytoma: a phase II study. (14630676)
2003
41
Development of secondary anaplastic oligoastrocytoma after matched unrelated bone marrow transplantation in a child with acute myeloid leukemia. (12853693)
2003
42
A phase II study of topotecan in patients with anaplastic oligodendroglioma or anaplastic mixed oligoastrocytoma. (14586216)
2003
43
Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets. (12107116)
2002
44
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. (10561351)
1999
45
Clinicohistological study of oligodendroglioma and oligoastrocytoma. (9384800)
1997
46
Molecular genetic evidence for subtypes of oligoastrocytomas. (9329453)
1997
47
Detection of JC virus DNA sequence and expression of the viral oncoprotein, tumor antigen, in brain of immunocompetent patient with oligoastrocytoma. (8692997)
1996
48
Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma. (7815084)
1995
49
Heterotransplantation of a human oligoastrocytoma into nude mice: difference in tumour growth between males and females. (1579199)
1992
50
Glial fibrillary acidic protein (GFAP) in oligodendroglial tumors: gliofibrillary oligodendroglioma and transitional oligoastrocytoma as subtypes of oligodendroglioma. (6391068)
1984

Variations for Oligoastrocytoma

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Cosmic variations for Oligoastrocytoma:

7 (show all 1,156)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
111323TP53central nervous system,brain,glioma,astrocytoma Grade IV3
210863TP53central nervous system,brain,glioma,astrocytoma Grade IV3
311498TP53central nervous system,brain,glioma,NS3
443833TP53central nervous system,brain,glioma,NS3
544623TP53central nervous system,brain,glioma,astrocytoma Grade IV3
645179TP53central nervous system,brain,glioma,astrocytoma Grade IV3
743746TP53central nervous system,brain,glioma,astrocytoma Grade IV3
81162159TP53central nervous system,brain,glioma,astrocytoma Grade IV3
944344TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1044175TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1144606TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1243616TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1343544TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1443945TP53central nervous system,brain,glioma,NS3
1510912TP53central nervous system,brain,glioma,NS3
1610834TP53central nervous system,brain,glioma,NS3
1744045TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1811449TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1945268TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2010762TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2110735TP53central nervous system,brain,glioma,astrocytoma Grade IV3
226549TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2344788TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2444014TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2544343TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2643714TP53central nervous system,brain,glioma,oligodendroglioma3
2711305TP53central nervous system,brain,glioma,NS3
2811133TP53central nervous system,brain,glioma,astrocytoma Grade IV3
2944215TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3044102TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3144555TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3243829TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3344320TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3443941TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3544776TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3643582TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3710645TP53central nervous system,brain,glioma,NS3
3810670TP53central nervous system,brain,glioma,astrocytoma Grade IV3
3945717TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4010731TP53central nervous system,brain,glioma,NS3
4143602TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4244151TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4344189TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4410788TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4543911TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4610905TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4743878TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4810719TP53central nervous system,brain,glioma,astrocytoma Grade IV3
4943843TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5044271TP53central nervous system,brain,glioma,NS3
5144204TP53central nervous system,brain,glioma,NS3
5211084TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5343912TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5444393TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5543879TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5643744TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5743765TP53central nervous system,brain,glioma,astrocytoma Grade IV3
5844226TP53central nervous system,brain,glioma,NS3
5944169TP53central nervous system,brain,glioma,NS3
6046274TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6145481TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6210870TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6344094TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6444188TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6543742TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6643814TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6710743TP53central nervous system,brain,glioma,oligoastrocytoma3
6843868TP53central nervous system,brain,glioma,astrocytoma Grade IV3
6943650TP53central nervous system,brain,glioma,oligoastrocytoma3
7044092TP53central nervous system,brain,glioma,NS3
7144557TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7245115TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7343901TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7443730TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7544964TP53central nervous system,brain,glioma,oligodendroglioma3
7643680TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7710801TP53central nervous system,brain,glioma,astrocytoma Grade IV3
7810718TP53central nervous system,brain,glioma,NS3
7944558TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8044190TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8139453TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8244380TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8345885TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8435846TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8544221TP53central nervous system,brain,glioma,NS3
8611564TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8711542TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8810760TP53central nervous system,brain,glioma,astrocytoma Grade IV3
8944911TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9046279TP53central nervous system,brain,glioma,astrocytoma Grade IV3
91133661TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9244202TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9310814TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9446124TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9510724TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9644200TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9710883TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9843871TP53central nervous system,brain,glioma,astrocytoma Grade IV3
9910941TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10011738TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10110939TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10243902TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10344198TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10446185TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10544570TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10644790TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10744262TP53central nervous system,brain,glioma,astrocytoma Grade IV3
108330674TP53central nervous system,brain,glioma,astrocytoma Grade IV3
10910738TP53central nervous system,brain,glioma,astrocytoma Grade IV3
11045368TP53central nervous system,brain,glioma,NS3
11143651TP53central nervous system,brain,glioma,NS3
11244383TP53central nervous system,brain,glioma,astrocytoma Grade IV3
11343615TP53central nervous system,brain,glioma,astrocytoma Grade IV3
11444877TP53central nervous system,brain,glioma,NS3
11543896TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1161651680TP53central nervous system,brain,glioma,astrocytoma Grade IV3
11711059TP53central nervous system,brain,glioma,NS3
11845035TP53central nervous system,brain,glioma,astrocytoma Grade IV3
11944829TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12043708TP53central nervous system,brain,glioma,oligodendroglioma3
12111123TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12246323TP53central nervous system,brain,glioma,astrocytoma Grade IV3
123143788TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12443931TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12511210TP53central nervous system,brain,glioma,NS3
12644613TP53central nervous system,brain,glioma,NS3
12710668TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12843823TP53central nervous system,brain,glioma,astrocytoma Grade IV3
12911665TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13043933TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13143545TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13244199TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13344556TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13444413TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13511152TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13643826TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13710742TP53central nervous system,brain,glioma,astrocytoma Grade IV3
138144210TP53central nervous system,brain,glioma,astrocytoma Grade IV3
13946261TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14043743TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14143596TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14210991TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14311198TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14410817TP53central nervous system,brain,glioma,oligoastrocytoma3
14510650TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14644219TP53central nervous system,brain,glioma,astrocytoma Grade IV3
14710667TP53central nervous system,brain,glioma,NS3
14843970TP53central nervous system,brain,glioma,NS3
14945047TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15011089TP53central nervous system,brain,glioma,astrocytoma Grade IV3
1516932TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15210659TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15310725TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15443548TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15510889TP53central nervous system,brain,glioma,NS3
15644525TP53central nervous system,brain,glioma,NS3
15710771TP53central nervous system,brain,glioma,NS3
15844334TP53central nervous system,brain,glioma,astrocytoma Grade IV3
15944561TP53central nervous system,brain,glioma,astrocytoma Grade IV3
160144162TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16145131TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16243739TP53central nervous system,brain,glioma,NS3
16343920TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16410957TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16545416TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16610756TP53central nervous system,brain,glioma,astrocytoma Grade IV3
16710722TP53central nervous system,brain,glioma,astrocytoma Grade IV3
168166369TP53central nervous system,brain,glioma,oligoastrocytoma3
16910943TP53central nervous system,brain,glioma,astrocytoma Grade IV3
17096436TP53central nervous system,brain,glioma,astrocytoma Grade IV3
17144303TP53central nervous system,brain,glioma,astrocytoma Grade IV3
17243923TP53central nervous system,brain,glioma,NS3
17310662TP53central nervous system,brain,glioma,astrocytoma Grade IV3
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10171088134PRPS1L1central nervous system,brain,glioma,NS3
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10311559709SPARCcentral nervous system,brain,glioma,astrocytoma Grade IV3
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10381580025PLCB1central nervous system,brain,glioma,astrocytoma Grade IV3
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104140633SOCS5central nervous system,brain,glioma,astrocytoma Grade IV3
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10431263470PTPRDcentral nervous system,brain,glioma,astrocytoma Grade IV3
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104740602SKIV2Lcentral nervous system,brain,glioma,astrocytoma Grade IV3
10481668574SLC35F3central nervous system,brain,glioma,NS3
1049132757RBL2central nervous system,brain,glioma,oligodendroglioma3
105039339RBM27central nervous system,brain,glioma,astrocytoma Grade IV3
10511410944REM1central nervous system,brain,glioma,astrocytoma Grade IV3
1052547465RERGLcentral nervous system,brain,glioma,astrocytoma Grade IV3
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105595220RUNX1T1central nervous system,brain,glioma,NS3
10561191677SCUBE1central nervous system,brain,glioma,astrocytoma Grade IV3
10571737543SDK1central nervous system,brain,glioma,astrocytoma Grade IV3
105841109SDR9C7central nervous system,brain,glioma,astrocytoma Grade IV3
105935754RTN1central nervous system,brain,glioma,astrocytoma Grade IV3
10601265475SH2D3Ccentral nervous system,brain,glioma,NS3
106140553RNF19Acentral nervous system,brain,glioma,astrocytoma Grade IV3
10621111027ROR2central nervous system,brain,glioma,NS3
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1064558476SLC9A5central nervous system,brain,glioma,astrocytoma Grade IV3
1065132768SLC9A6central nervous system,brain,glioma,oligodendroglioma3
106640519PTPRScentral nervous system,brain,glioma,astrocytoma Grade IV3
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10701673725PTPRN2central nervous system,brain,glioma,NS3
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107240518PTPRKcentral nervous system,brain,glioma,astrocytoma Grade IV3
10731668765RAB10central nervous system,brain,glioma,NS3
10741191873RAB28central nervous system,brain,glioma,astrocytoma Grade IV3
107539746RAPGEFL1central nervous system,brain,glioma,astrocytoma Grade IV3
10761374208SMAD3central nervous system,brain,glioma,NS3
10771737155RASEFcentral nervous system,brain,glioma,astrocytoma Grade IV3
1078990866RAB3Dcentral nervous system,brain,glioma,astrocytoma Grade IV3
107939603RAB3Ccentral nervous system,brain,glioma,astrocytoma Grade IV3
10801579879RAB34central nervous system,brain,glioma,astrocytoma Grade IV3
108140530RAB36central nervous system,brain,glioma,astrocytoma Grade IV3
108240433OSTM1central nervous system,brain,glioma,astrocytoma Grade IV3
1083425870OR2W5central nervous system,brain,glioma,astrocytoma Grade IV3
108440255LATS2central nervous system,brain,glioma,astrocytoma Grade IV3
108540254LATS1central nervous system,brain,glioma,astrocytoma Grade IV3
108640256LAX1central nervous system,brain,glioma,astrocytoma Grade IV3
10871737796LDHCcentral nervous system,brain,glioma,astrocytoma Grade IV3
10881737122TAB3central nervous system,brain,glioma,astrocytoma Grade IV3
108939287LAMA1central nervous system,brain,glioma,astrocytoma Grade IV3
109054432TAF4Bcentral nervous system,brain,glioma,NS3
10911736540TANC2central nervous system,brain,glioma,astrocytoma Grade IV3
10921212907KSR1central nervous system,brain,glioma,NS3
10931737050LIMK2central nervous system,brain,glioma,astrocytoma Grade IV3
109426928LIN28Acentral nervous system,brain,glioma,NS3
10951736851SYNE1central nervous system,brain,glioma,oligoastrocytoma3
10961627054MACF1central nervous system,brain,glioma,astrocytoma Grade IV3
109743037MAGEA1central nervous system,brain,glioma,astrocytoma Grade IV3
109840282LRRN2central nervous system,brain,glioma,astrocytoma Grade IV3
10991669290LRP1Bcentral nervous system,cerebrum,glioma,astrocytoma Grade I3
110035502KPNA2central nervous system,brain,glioma,astrocytoma Grade IV3
110139227TAOK1central nervous system,brain,glioma,astrocytoma Grade IV3
110242734IRAK3central nervous system,brain,glioma,astrocytoma Grade IV3
110313332IRAK1central nervous system,brain,glioma,NS3
11041600149TAOK3central nervous system,brain,glioma,astrocytoma Grade IV3
110535438ITGB3central nervous system,brain,glioma,astrocytoma Grade IV3
11061736931ITPR2central nervous system,brain,glioma,astrocytoma Grade IV3
110740201IPO8central nervous system,brain,glioma,astrocytoma Grade IV3
110813331INSRRcentral nervous system,brain,glioma,NS3
110935551ING4central nervous system,brain,glioma,astrocytoma Grade IV3
11101292568SEMA3Ecentral nervous system,brain,glioma,astrocytoma Grade IV3
1111240239INSRcentral nervous system,brain,glioma,astrocytoma Grade IV3
11121443881ITPR3central nervous system,brain,glioma,astrocytoma Grade IV3
11131736896KDM1Bcentral nervous system,brain,glioma,oligoastrocytoma3
111440213KCNK5central nervous system,brain,glioma,astrocytoma Grade IV3
111540994KIAA1804central nervous system,brain,glioma,astrocytoma Grade IV3
111640209KATNAL2central nervous system,brain,glioma,astrocytoma Grade IV3
11171676183KAT5central nervous system,brain,glioma,NS3
11181191957JAG2central nervous system,brain,glioma,astrocytoma Grade IV3
111912600JAK2central nervous system,brain,glioma,astrocytoma Grade IV3
11201679282KARScentral nervous system,brain,glioma,NS3
112140298MAN2A1central nervous system,brain,glioma,astrocytoma Grade IV3
11221191917MAP3K10central nervous system,brain,glioma,astrocytoma Grade IV3
1123144954NFKB1central nervous system,brain,glioma,astrocytoma Grade IV3
11241736841NFKBIBcentral nervous system,brain,glioma,oligoastrocytoma3
112541064NKRFcentral nervous system,brain,glioma,astrocytoma Grade IV3
112640380NLNcentral nervous system,brain,glioma,astrocytoma Grade IV3
11271486600STK10central nervous system,brain,glioma,astrocytoma Grade IV3
11281559505STK11central nervous system,brain,glioma,astrocytoma Grade IV3
112940347MTRcentral nervous system,brain,glioma,astrocytoma Grade IV3
1130420536MUC7central nervous system,brain,glioma,NS3
113135784MYLK2central nervous system,brain,glioma,astrocytoma Grade IV3
113240662STX12central nervous system,brain,glioma,astrocytoma Grade IV3
11331680324NOL4central nervous system,brain,glioma,NS3
113439206NUP160central nervous system,brain,glioma,astrocytoma Grade IV3
1135132739NUP188central nervous system,brain,glioma,oligodendroglioma3
11361600217NUTM2Bcentral nervous system,brain,glioma,astrocytoma Grade IV3
113740650SPOCK3central nervous system,brain,glioma,astrocytoma Grade IV3
113872832STAU1central nervous system,brain,glioma,astrocytoma Grade IV3
11391736167NOTCH2NLcentral nervous system,brain,glioma,astrocytoma Grade IV3
11401191619NOTCH3central nervous system,brain,glioma,astrocytoma Grade IV3
11411736971SULF2central nervous system,brain,glioma,astrocytoma Grade IV3
114239597MRPL16central nervous system,brain,glioma,astrocytoma Grade IV3
114335379MAPK9central nervous system,brain,glioma,astrocytoma Grade IV3
114442782MAPK8IP3central nervous system,brain,glioma,astrocytoma Grade IV3
114539634MAP3K11central nervous system,brain,glioma,astrocytoma Grade IV3
114640802ZW10central nervous system,brain,glioma,astrocytoma Grade IV3
11471737531MC2Rcentral nervous system,brain,glioma,astrocytoma Grade IV3
114839732MCPH1central nervous system,brain,glioma,astrocytoma Grade IV3
114941025MON2central nervous system,brain,glioma,astrocytoma Grade IV3
11501737799MRE11Acentral nervous system,brain,glioma,astrocytoma Grade IV3
11511737233MIB1central nervous system,brain,glioma,astrocytoma Grade IV3
115240314METTL5central nervous system,brain,glioma,astrocytoma Grade IV3
115335414MDM2central nervous system,brain,glioma,astrocytoma Grade IV3
1154131834MED12central nervous system,brain,glioma,astrocytoma Grade IV3
11551267026SUMF2central nervous system,brain,glioma,NS3
1156261422ING2central nervous system,brain,glioma,astrocytoma Grade IV3

Expression for genes affiliated with Oligoastrocytoma

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Search GEO for disease gene expression data for Oligoastrocytoma.

Pathways for genes affiliated with Oligoastrocytoma

About this section

Pathways related to Oligoastrocytoma according to GeneCards Suite gene sharing:

(show all 13)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
Angiogenesis36
9.6PDGFB, PDGFRA
2
Show member pathways
PDGF Pathway36
9.6PDGFB, PDGFRA
39.6PDGFB, PDGFRA
4
Show member pathways
9.3GFAP, PDGFRA, PDGFB
59.3PDGFB, PDGFRA, TP53
6
Show member pathways
Development EGFR signaling via PIP358
Development PDGF signaling via MAPK cascades58
Apoptosis and survival Anti apoptotic action of membrane bound ESR158
Signaling of Hepatocyte Growth Factor Receptor36
Development EGFR signaling via small GTPases58
Development Neurotrophin family signaling58
Apoptosis and survival NGF signaling pathway58
Apoptosis and survival Role of CDK5 in neuronal death and survival58
9.3PDGFB, PDGFRA, TP53
7
Show member pathways
Signaling Pathways in Glioblastoma36
9.3TP53, PDGFRA, PDGFB
89.0PDGFB, PDGFRA, TP53, MGMT
9
Show member pathways
8.8TP53, CXCR4, PDGFRA, PDGFB
10
Show member pathways
8.8PDGFB, PDGFRA, CXCR4, TP53
11
Show member pathways
8.8TP53, CXCR4, PDGFRA, PDGFB
12
Show member pathways
8.8TP53, CXCR4, PDGFRA, PDGFB
13
Show member pathways
8.5GFAP, TP53, CXCR4, PDGFRA, PDGFB

Compounds for genes affiliated with Oligoastrocytoma

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Compounds related to Oligoastrocytoma according to GeneCards Suite gene sharing:

(show all 46)
idCompoundScoreTop Affiliating Genes
1n-ethyl-n-nitrosourea4310.3MGMT, GFAP
2sarcnu4310.3MGMT, TP53
3Oxalosuccinic acid2410.3IDH1, IDH2
4acnu4310.3MGMT, TP53
5lomustine43 1211.3MGMT, TP53
6o6-benzylguanine4310.2MGMT, TP53
7Isocitric acid24 1211.2IDH2, IDH1
8chlorambucil43 1211.2TP53, MGMT
95-methylcytosine43 2411.2TP53, MGMT
10o6-methylguanine4310.1MGMT, TP53
112-mercaptoethanol4310.1NES, GFAP
12sn 3843 5911.1MGMT, TP53
13streptozotocin4310.1NES, GFAP, MGMT
14temozolomide43 1211.1MGMT, TP53, NES
15bcnu4310.1TP53, GFAP, MGMT
16dmpq dihydrochloride5910.0PDGFRA, PDGFB
17su 16f5910.0PDGFRA, PDGFB
18su 66685910.0PDGFRA, PDGFB
19sunitinib malate5910.0PDGFRA, PDGFB
20isocitrate439.9IDH2, IDH1
21dutp439.9TP53, GFAP
22crcs439.9MGMT, TP53
23bromodeoxyuridine439.9PDGFB, NES, GFAP
24gaba439.8FABP7, NES, GFAP
25Oxoglutaric acid249.8IDH1, IDH2
26carboplatin43 49 1211.7CXCR4, TP53, MGMT
27cyclophosphamide43 49 1211.7CXCR4, TP53, MGMT
285-aza-2deoxycytidine439.7MGMT, TP53, CXCR4
29matrigel439.6GFAP, NES, CXCR4
30agar439.5GFAP, CXCR4, PDGFB
31paclitaxel43 49 1211.5MGMT, GFAP, TP53, CXCR4
32cisplatin43 49 59 1212.4MGMT, GFAP, TP53, CXCR4
33imatinib43 49 1211.4CXCR4, PDGFRA, PDGFB
34nadph43 2410.4CXCR4, IDH1, IDH2, MGMT
35progesterone43 28 59 24 1213.4MGMT, GFAP, TP53, NES, PDGFB
36cycloheximide439.3PDGFB, CXCR4, TP53, GFAP
37thymidine43 2410.2MGMT, GFAP, TP53, PDGFRA, PDGFB
38dexamethasone43 49 28 1212.1PDGFB, CXCR4, GFAP, MGMT
39butyrate439.1CXCR4, TP53, GFAP
40glucose439.1MGMT, GFAP, NES, CXCR4, PDGFB
41glutamate439.1CXCR4, FABP7, NES, GFAP, IDH1
42paraffin438.9PDGFB, PDGFRA, NES, TP53, GFAP, MGMT
43oligonucleotide438.9MGMT, TP53, CXCR4, PDGFRA, PDGFB
44retinoic acid43 249.5MGMT, GFAP, TP53, NES, FABP7, CXCR4
45vegf438.4MGMT, GFAP, TP53, NES, CXCR4, PDGFRA
46estrogen438.4MGMT, GFAP, TP53, NES, CXCR4, PDGFRA

GO Terms for genes affiliated with Oligoastrocytoma

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Cellular components related to Oligoastrocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytoplasmGO:00057376.9PDGFB, PDGFRA, CXCR4, FABP7, NES, TP53

Biological processes related to Oligoastrocytoma according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1glyoxylate cycleGO:000609710.1IDH1, IDH2
2isocitrate metabolic processGO:000610210.1IDH1, IDH2
32-oxoglutarate metabolic processGO:000610310.1IDH2, IDH1
4cellular response to ionizing radiationGO:007147910.1TP53, MGMT
5tricarboxylic acid cycleGO:00060999.9IDH1, IDH2
6positive regulation of reactive oxygen species metabolic processGO:020003799.9TP53, PDGFB
7negative regulation of platelet activationGO:00105449.9PDGFB, PDGFRA
8positive regulation of phosphatidylinositol 3-kinase activityGO:00435529.8PDGFB, PDGFRA
9regulation of chemotaxisGO:00509209.8PDGFRA, CXCR4
10platelet-derived growth factor receptor signaling pathwayGO:00480089.7PDGFRA, PDGFB
11positive regulation of DNA replicationGO:00457409.6PDGFB, PDGFRA
12cell chemotaxisGO:00603269.6PDGFB, PDGFRA
13cellular protein localizationGO:00346139.5ID4, TP53
14positive regulation of fibroblast proliferationGO:00481469.3PDGFB, PDGFRA

Molecular functions related to Oligoastrocytoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1isocitrate dehydrogenase (NADP+) activityGO:00044509.9IDH1, IDH2
2NAD bindingGO:00512879.9IDH1, IDH2
3platelet-derived growth factor bindingGO:00484079.6PDGFB, PDGFRA
4platelet-derived growth factor receptor bindingGO:00051619.5PDGFRA, PDGFB
5RNA polymerase II transcription factor bindingGO:00010859.3TP53, ID4

Products for genes affiliated with Oligoastrocytoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Oligoastrocytoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet