MCID: OLG002
MIFTS: 67

Oligodendroglioma malady

Neuronal diseases, Cancer diseases categories

Summaries for Oligodendroglioma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the... more...

MalaCards: Oligodendroglioma, also known as oligodendroglial neoplasm, is related to astrocytoma and dysembryoplastic neuroepithelial tumor. An important gene associated with Oligodendroglioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Rho Family GTPases and Pathways in cancer. The compounds retinoic acid and vegf have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial, and related mouse phenotypes are mortality/aging and immune system.

Aliases & Classifications for Oligodendroglioma

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 22GTR, 10DISEASES, 44Novoseek, 48Orphanet, 60UMLS, 34MeSH, 56SNOMED-CT, 39NCIt, 57SNOMED-CT via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
oligodendroglioma:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

oligodendroglioma 8 42 22 10 44 48 60
oligodendroglial neoplasm 8 60
oligodendroglial tumors 44
oligodendroglial tumor 8
oligodendroglioma nos 8


External Ids:

Disease Ontology8 DOID:3181
MeSH34 D009837
NCIt39 C3288
SNOMED-CT via Orphanet57 443936004, 73348003

Related Diseases for Oligodendroglioma

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17GeneCards, 18GeneDecks
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Diseases in the Oligodendroglioma family:

Adult Oligodendroglioma

Diseases related to Oligodendroglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 203)
idRelated DiseaseScoreTop Affiliating Genes
1astrocytoma30.9TP53, LGALS3, PTEN, KDR, GFAP, OLIG2
2dysembryoplastic neuroepithelial tumor30.5OLIG2
3anaplastic oligodendroglioma30.4LGALS3, PTEN, KDR, GFAP, OLIG2, OLIG1
4central neurocytoma30.3GFAP, OLIG2
5leukemia30.2TP53, KDR, OLIG2, CDKN2C, CDK2, CDK4
6brain cancer30.1EGFR, MDM2, MGMT
7sarcoma30.0TP53, KDR, CDK2, CDK4, RB1, STMN1
8meningioma30.0PTEN, GFAP, CDKN2C, CDKN2B
9acute leukemia30.0CDKN2C, CDKN2B, IGFBP2, STMN1
10neuroblastoma30.0TP53
11oligoastrocytoma30.0GFAP, MGMT
12mixed glioma30.0GFAP, PDGFRA
13melanoma29.8TP53, LGALS3, PTEN, KDR, CDKN2C, CDK2
14glioblastoma multiforme29.8TP53, PTEN, KDR, GFAP, CDK4, CDKN2B
15breast cancer29.8TP53, LGALS3, PTEN, KDR, CDKN2C, CDK2
16adenoma29.8TP53, LGALS3, CDKN2C, CDK2, CDK4, CDKN2A
17medulloblastoma29.8TP53, GFAP, CDK4, CDKN2B, STMN1, DMBT1
18pituitary adenoma29.8LGALS3, CDK4, CDKN2B, RB1, MGMT
19rhabdomyosarcoma29.8TP53, CDK4, RB1, MDM2, PDGFRA
20gliosarcoma29.8PTEN, GFAP, CDK4
21neurofibromatosis29.8PDGFRA
22meningitis29.8IGFBP2
23lynch syndrome29.8TP53
24non-hodgkin lymphoma29.8CDKN2C, CDKN2B, STMN1, MDM2
25brain oligodendroglioma10.5
26spinal cord oligodendroglioma10.5
27cerebritis10.5
28adult oligodendroglioma10.4
29childhood oligodendroglioma10.3
30mixed oligodendroglioma-astrocytoma10.2
31neuronitis10.2
32multiple sclerosis10.2
33clear cell ependymoma10.2
34arteriovenous malformation10.1
35ovarian cystic teratoma10.1
36mixed astrocytoma-ependymoma-oligodendroglioma10.1
37cystic teratoma10.1
38mature teratoma10.1
39glomerulosclerosis, focal segmental, 610.1
40granular cell tumor10.1
41cerebral angioma10.0
42brain sarcoma10.0
43pleomorphic xanthoastrocytoma10.0
44cervicitis10.0
45anaplastic astrocytoma10.0TP53, LGALS3, PTEN, GFAP, OLIG2, OLIG1
46squamous cell carcinoma10.0TP53, LGALS3, PTEN, KDR, CDK2, CDK4
47adenocarcinoma10.0TP53, LGALS3, PTEN, KDR, CDK2, CDK4
48malignant glioma10.0TP53, PTEN, KDR, GFAP, OLIG2, CDK4
49hepatocellular carcinoma10.0TP53, PTEN, KDR, CDKN2C, CDK2, CDK4
50ovarian cancer10.0TP53, PTEN, KDR, CDKN2C, CDK2, CDK4

Graphical network of the top 20 diseases related to Oligodendroglioma:



Diseases related to oligodendroglioma

Clinical Features for Oligodendroglioma

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Drugs & Therapeutics for Oligodendroglioma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Oligodendroglioma

Drug clinical trials:

Search ClinicalTrials for Oligodendroglioma

Search NIH Clinical Center for Oligodendroglioma

Search CenterWatch for Oligodendroglioma

Genetic Tests for Oligodendroglioma

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22GTR
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Genetic tests related to Oligodendroglioma:

id Genetic test Affiliating Genes
1 Oligodendroglioma22

Anatomical Context for Oligodendroglioma

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32MalaCards
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MalaCards organs/tissues related to Oligodendroglioma:

32
Brain, Spinal cord, Endothelial, Bone, Bone marrow, Temporal lobe, Breast, Tongue, Medulla oblongata, Pineal, Parietal lobe, B cells, Myeloid, Cerebellum, Pituitary

Animal Models for Oligodendroglioma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Oligodendroglioma:

36 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:001076811.6CDKN2B, CDKN2A, EGFR, RB1, DMBT1, MDM2
2MP:000538711.5CDKN2A, IGFBP2, EGFR, RB1, DMBT1, MDM2
3MP:000538411.5CDKN2B, CDKN2A, EGFR, RB1, DMBT1, MDM2
4MP:000200611.4TP53, PDGFRA, MGMT, MDM2, DMBT1, RB1
5MP:000538511.4IGFBP2, EGFR, RB1, STMN1, MDM2, PDGFRA
6MP:000539711.4CDKN2A, IGFBP2, EGFR, RB1, MDM2, PDGFRA
7MP:000537811.3CDK4, CDKN2A, EGFR, RB1, MDM2, PDGFRA
8MP:000536911.3PDGFRA, MDM2, STMN1, RB1, CDKN2A, CDK4
9MP:001077111.3PDGFRA, MDM2, RB1, CDKN2A, CDKN2B, CDK4
10MP:000538111.2RB1, DMBT1, MDM2, PDGFRA, EGFR, CDKN2A
11MP:000537011.1MDM2, RB1, EGFR, IGFBP2, CDKN2A, CDK4
12MP:000537611.1PDGFRA, MGMT, DMBT1, STMN1, CDK4, CDKN2C
13MP:000301211.1MGMT, MDM2, RB1, EGFR, CDKN2A, CDKN2B
14MP:000538911.1PDGFRA, EGFR, CDKN2A, CDKN2B, CDK2, CDKN2C
15MP:000537911.1PDGFRA, MGMT, RB1, CDKN2A, CDKN2B, CDK4
16MP:000363111.0CDK4, OLIG1, OLIG2, GFAP, LGALS3
17MP:000538811.0TP53, PDGFRA, RB1, EGFR, CDKN2C, OLIG2
18MP:000536710.9LGALS3, EGFR, DMBT1
19MP:000287310.8PDGFRA, MDM2, STMN1, RB1, EGFR, IGFBP2
20MP:000538210.7MDM2, RB1, EGFR, PTEN, TP53, PDGFRA
21MP:000538010.7DMBT1
22MP:000539010.6PDGFRA, RB1, OLIG2, LGALS3
23MP:000538610.6CDKN2A, RB1, MDM2, PDGFRA, CDK4, CDKN2C
24MP:000539110.6GFAP, EGFR

Publications for Oligodendroglioma

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50PubMed
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Articles related to Oligodendroglioma:

(show top 50)    (show all 599)
idTitleAuthorsYear
1
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and I+-KG. (24252742)
2013
2
Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. (23071247)
2013
3
Glioblastoma with oligodendroglioma component (GBM-O): molecular genetic and clinical characteristics. (23289977)
2013
4
Glioblastoma with an oligodendroglioma component: distinct clinical behavior, genetic alterations, and outcome. (22326863)
2012
5
Pediatric brainstem oligodendroglioma. (22346193)
2012
6
Sudden unexpected death from oligodendroglioma: a case report and review of the literature. (20375839)
2011
7
Multifocal oligodendroglioma in three dogs. (21896836)
2011
8
Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. (20236756)
2010
9
First report of oligodendroglioma in a sheep. (21247018)
2010
10
Primary diffuse leptomeningeal oligodendroglioma. (21196802)
2010
11
Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis. (19558288)
2009
12
Incidence of and survival from oligodendroglioma in Denmark, 1943-2002. (19066344)
2009
13
Oligodendroglioma. (18272388)
2008
14
Secondary anaplastic oligodendroglioma after cranial irradiation: a case report. (18373067)
2008
15
The use of magnetic resonance imaging to noninvasively detect genetic signatures in oligodendroglioma. (18413825)
2008
16
Loss of heterozygosity analysis in an anaplastic oligodendroglioma arising after radiation therapy. (17553214)
2007
17
Qualitative and quantitative analysis of cytologic assessment of astrocytoma, oligodendroglioma and oligoastrocytoma. (18077983)
2007
18
Intracranial dissemination of primary spinal cord anaplastic oligodendroglioma. (17437621)
2007
19
Gene dosage and mutational analyses of EGFR in oligodendrogliomas. (17143531)
2007
20
Anaplastic mixed gliomas and anaplastic oligodendroglioma in children: results from the CCG 945 experience. (17252186)
2007
21
The SHREW1 gene, frequently deleted in oligodendrogliomas, functions to inhibit cell adhesion and migration. (16410724)
2006
22
Primary spinal cord oligodendroglioma. Case illustration. (17242843)
2006
23
Cerebellar oligodendroglioma in a young adult. (16169228)
2005
24
Population-based study on incidence, survival rates, and genetic alterations of low-grade diffuse astrocytomas and oligodendrogliomas. (15118874)
2004
25
Efficacy and feasibility of standard procarbazine, lomustine, and vincristine chemotherapy in anaplastic oligodendroglioma and oligoastrocytoma recurrent after radiotherapy. A Phase II study. (15372474)
2004
26
Imaging molecular signatures in oligodendroglioma. (15534080)
2004
27
Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. (12456321)
2003
28
Oligodendroglioma in a French bulldog. (14610376)
2003
29
Oligodendroglioma: toward molecular definitions in diagnostic neuro-oncology. (12578221)
2003
30
CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans. (12635659)
2002
31
PCV chemotherapy for oligodendroglioma: response analyzed on T2 weighted-MRI. (11804282)
2001
32
Prognostic significance of clinical and angiogenesis-related factors in low-grade oligodendrogliomas. (11118569)
2000
33
Cyclooxygenase (COX)-1 expressing macrophages/microglial cells and COX-2 expressing astrocytes accumulate during oligodendroglioma progression. (11121536)
2000
34
Central neurocytomas are genetically distinct from oligodendrogliomas and neuroblastomas. (10931240)
2000
35
Superficially-located oligodendroglioma associated with intratumoral and peritumoral cysts--case report. (10927907)
2000
36
Immunohistochemical investigation of p53 and EGFR expression of oligodendrogliomas. (10442459)
1999
37
Oligodendroglioma of the "widespread" type in the spinal cord. (9881630)
1998
38
Dysembryoplastic neuroepithelial tumor and oligodendroglioma: the diagnostic value of magnetic resonance spectroscopy. Case report and review of the literature. (17168506)
1998
39
Prognostic implication of histopathological, immunohistochemical and clinical features of oligodendrogliomas: a study of 89 cases. (9600596)
1998
40
Glycolipids and myelin proteins in human oligodendrogliomas. (8781974)
1996
41
Mucinous oligodendroglioma of the spinal cord in a dog. (7820760)
1995
42
Aggressive oligodendroglioma: a chemosensitive tumor. (8047688)
1994
43
Recurrent oligodendroglioma diagnosed with 11C-L-methionine and PET: a case report. (8467848)
1993
44
Expression of p53 in oligodendrogliomas. (8158458)
1993
45
Lectins: reliable differentiation markers in human oligodendrogliomas. (8220777)
1993
46
Oligodendrogliomas: a clinical, histological, immunocytochemical and lectin-binding study. (1937415)
1991
47
Subarachnoid hemorrhage in the presence of a cerebral arteriovenous malformation and an intraventricular oligodendroglioma: case report. (3748333)
1986
48
Metastatic oligodendroglioma presenting as a leukoerythroblastic anaemia. (4029411)
1985
49
Oligodendroglioma of the posterior fossa in childhood. (4005789)
1985
50
Temporal lobe oligodendroglioma developing from infancy into adulthood. (617597)
1977

Genetic Variations for Oligodendroglioma

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Expression for genes affiliated with Oligodendroglioma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Oligodendroglioma

Search GEO for disease gene expression data for Oligodendroglioma.

Pathways for genes affiliated with Oligodendroglioma

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Sources:
51QIAGEN, 29KEGG, 37NCBI BioSystems Database, 52R&D Systems, 53Reactome, 4Cell Signaling Technology, 12EMD Millipore, 55SinoBiological, 59Tocris Bioscience
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Pathways related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 65)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.1CDKN2B, CDKN2A, EGFR, RB1, STMN1, MDM2
210.9PDGFRA, MDM2, RB1, EGFR, CDKN2A, CDKN2B
310.9CDKN2A, MGMT, PDGFRA, MDM2, PTEN, CDK2
410.8CDK2, PTEN, TP53, CDK4, CDKN2B, EGFR
5
Hide members
10.8KDR, PDGFRA, MDM2, RB1, CDKN2A, PTEN
610.8KDR, PTEN, PDGFRA, MDM2, EGFR, CDK4
710.8TP53, PTEN, KDR, CDK2, CDK4, EGFR
810.8RB1, CDKN2C, CDK4, CDKN2B, PDGFRA, TP53
9
Hide members
10.8CDK4, CDKN2C, CDKN2B, CDKN2A, RB1, MDM2
10
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10.8MGMT, CDKN2C, CDK4, CDKN2A, MDM2, RB1
11
Hide members
10.8RB1, CDKN2A, CDKN2B, CDKN2C, CDK4, CDK2
12
Hide members
10.8PDGFRA, CDKN2C, MDM2, RB1, CDKN2B, CDK2
1310.8LGALS3, TP53, CDK2, GFAP, EGFR, CDK4
1410.8MDM2, PTEN, STMN1, CDKN2A, EGFR, TP53
1510.8MDM2, RB1, CDKN2A, CDK4, CDK2, TP53
16
Hide members
10.8MDM2, TP53, CDK2, CDK4, CDKN2A, PTEN
17
Transcription P53 signaling pathway
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10.8TP53, CDKN2A, KDR, CDK2, CDK4, MDM2
1810.8CDK4, RB1, MDM2, PTEN, CDK2, EGFR
19
Hide members
10.7KDR, EGFR, MDM2, PTEN, PDGFRA, TP53
20
Hide members
10.7TP53, PDGFRA, PTEN, KDR, EGFR, MDM2
21
Hide members
10.7PDGFRA, STMN1, CDKN2B, CDK4, CDK2, TP53
22
Hide members
10.7MDM2, RB1, EGFR, CDKN2A, TP53, CDK4
2310.7RB1, CDKN2B, TP53, PTEN, CDK2, CDK4
24
Hide members
10.7CDKN2A, CDKN2C, CDK2, TP53, RB1, MDM2
25
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10.7MDM2, RB1, CDK4, CDK2, PTEN, TP53
26
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10.7PDGFRA, MDM2, EGFR, GFAP, PTEN
27
Cell cycle Cell cycle (generic schema)
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10.7RB1, CDKN2A, CDKN2B, CDK4, CDK2
28
Hide members
10.7PDGFRA, RB1, EGFR, PTEN, KDR
29
Hide members
10.7MGMT, MDM2, CDK4, CDK2, RB1
3010.7TP53, PTEN, CDKN2A, RB1, MDM2
31
Hide members
10.7MDM2, CDK4, CDK2, PTEN, RB1
3210.7MDM2, RB1, PTEN, TP53, EGFR
33
Hide members
10.7TP53, CDK4, CDK2, PTEN, RB1
34
Hide members
10.6CDKN2A, MDM2, PTEN, TP53
35
Hide members
10.6PTEN, EGFR, MDM2, TP53
3610.6PTEN, EGFR, RB1, MDM2
3710.6MGMT, TP53, CDK2, CDK4
3810.6TP53, CDKN2A, RB1, MDM2
3910.6CDK4, CDK2, TP53, MDM2
40
Hide members
10.6RB1, CDK4, PTEN, CDK2
41
Hide members
10.6PTEN, IGFBP2, MDM2, TP53
42
Hide members
10.6PDGFRA, KDR, MDM2
4310.6CDKN2A, MDM2, TP53
4410.6MDM2, CDKN2A, TP53
4510.6CDK4, CDK2, TP53
4610.6CDK2, CDK4, RB1
4710.6MDM2, CDK2, TP53
4810.6RB1, KDR, CDK2
4910.6RB1, CDK2
5010.6RB1, CDK2

Compounds for genes affiliated with Oligodendroglioma

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Sources:
44Novoseek, 24HMDB, 49PharmGKB, 59Tocris Bioscience, 11DrugBank, 28IUPHAR, 2BitterDB
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Compounds related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 174)
idCompoundScoreTop Affiliating Genes
1retinoic acid44 2412.6CDKN2A, PTEN, KDR, GFAP, OLIG2, IGFBP2
2vegf4411.5TP53, LGALS3, KDR, GFAP, CDK2, CDK4
3cisplatin44 49 59 1114.5CDK2, GFAP, KDR, PTEN, LGALS3, TP53
4progesterone44 59 28 11 2415.5CDK2, CDK4, CDKN2A, IGFBP2, EGFR, STMN1
5tyrosine4411.4PTEN, LGALS3, IGFBP2, EGFR, RB1, STMN1
6paclitaxel44 49 1113.4CDK2, GFAP, KDR, PTEN, MDM2, STMN1
7doxorubicin44 49 1113.4MGMT, MDM2, STMN1, RB1, EGFR, CDKN2A
8thymidine44 2412.4KDR, PDGFRA, MGMT, STMN1, IGFBP2, CDK4
9oligonucleotide4411.3PDGFRA, TP53, PTEN, CDK4, IGFBP2, RB1
10threonine4411.3CDKN2A, RB1, STMN1, CDK2, MDM2, PTEN
115fluorouracil4411.3CDKN2A, CDK4, CDK2, KDR, PTEN, TP53
12agar4411.3LGALS3, RB1, PTEN, EGFR, CDKN2A, GFAP
13genistein44 28 59 2 11 2416.3MDM2, KDR, MGMT, RB1, CDKN2A, GFAP
14paraffin4411.3MGMT, MDM2, EGFR, CDK4, GFAP, KDR
15arginine4411.2CDKN2A, IGFBP2, MDM2, CDK4, GFAP, TP53
16pd 98,0594411.2GFAP, PTEN, CDKN2B, EGFR, CDK2, RB1
17rapamycin4411.2CDK2, KDR, PTEN, IGFBP2, EGFR, RB1
18phosphatidylinositol4411.2EGFR, IGFBP2, RB1, CDK4, MDM2, PDGFRA
19ly2940024411.2KDR, TP53, PTEN, MDM2, CDK2, CDK4
20thymidylate4411.2EGFR, RB1, CDKN2A, CDK4, CDK2, TP53
21camptothecin44 59 1113.2TP53, KDR, CDK2, RB1, MGMT, MDM2
22flavopiridol44 1112.2MDM2, RB1, EGFR, CDKN2A, CDK4, CDK2
23carboplatin44 49 1113.2CDK4, RB1, TP53, MDM2, MGMT, EGFR
24oxygen44 2412.1IGFBP2, GFAP, LGALS3, CDK4, CDKN2A, RB1
25testosterone44 59 11 2414.1EGFR, CDK2, IGFBP2, RB1, MDM2, PTEN
26mg 13244 5912.1PTEN, KDR, TP53, CDKN2A, EGFR, CDK2
27serine4411.1GFAP, CDKN2C, CDKN2B, STMN1, DMBT1
28cysteine4411.1LGALS3, CDK4, GFAP, CDKN2A, RB1, KDR
29roscovitine4411.1CDK2, CDK4, CDKN2A, TP53, RB1, MDM2
30trastuzumab44 49 1113.1PTEN, CDK2, CDK4, EGFR, MDM2, KDR
31gefitinib44 49 1113.1EGFR, PTEN, KDR, CDK2, CDK4, MDM2
32olomoucine44 1112.1TP53, CDK2, CDK4, CDKN2A, RB1
33calcium44 49 11 2414.0CDK4, IGFBP2, STMN1, LGALS3, GFAP, DMBT1
34bcnu4411.0GFAP, TP53, MGMT, CDKN2A, EGFR
35adpribose4411.0MDM2, CDK4, TP53, RB1, CDK2, EGFR
36geldanamycin44 49 59 1114.0MDM2, EGFR, KDR, CDK4, TP53, CDK2
37cytarabine44 49 1113.0TP53, CDK2, GFAP, CDKN2B, CDKN2A, RB1
38crcs4411.0CDKN2A, MGMT, TP53, RB1, PTEN
39dexamethasone44 49 28 1114.0RB1, MGMT, MDM2, KDR, CDK2, CDKN2A
40estrogen4411.0GFAP
41etoposide44 49 59 1113.9CDK2, RB1, LGALS3, MDM2
42nitric oxide44 11 2412.9MGMT, CDKN2A, CDK4, CDK2, KDR, PTEN
43cycloheximide4410.8IGFBP2
44tgf beta14410.8CDK4, KDR, CDK2, CDKN2B, PDGFRA, PTEN
45vincristine44 49 1112.8MGMT, RB1
46cyclophosphamide44 49 1112.8PTEN, TP53, MDM2, KDR, RB1, MGMT
47butyrate4410.7GFAP, CDK2
48imatinib44 49 1112.6PTEN, EGFR, MDM2, PDGFRA, CDK2, KDR
49fascaplysin4410.6CDK2, CDK4, CDKN2A
50curcumin4410.4CDK2, MGMT, TP53, MDM2, CDK4, EGFR

GO Terms for genes affiliated with Oligodendroglioma

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16Gene Ontology
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Cellular components related to Oligodendroglioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:00563411.3TP53, PDGFRA, MGMT, MDM2, RB1, EGFR
2cytoplasmGO:00573711.2PDGFRA, MDM2, DMBT1, EGFR, CDKN2A, CDKN2B
3cytosolGO:00582911.0MDM2, STMN1, CDKN2A, CDKN2B, CDK4, CDK2
4nucleoplasmGO:00565410.8MGMT, MDM2, RB1, CDKN2A, CDK4, CDK2
5nuclear bodyGO:01660410.7MDM2, CDKN2A, TP53
6PML bodyGO:01660510.6TP53, PTEN, RB1
7chromatinGO:00078510.5RB1, CDK4, TP53
8cyclin-dependent protein kinase holoenzyme complexGO:00030710.3CDK2, CDK4

Biological processes related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell proliferationGO:00828411.1PTEN, KDR, CDK2, CDK4, EGFR, MDM2
2mitotic cell cycleGO:00027811.1RB1, CDKN2A, CDKN2B, CDK4, CDK2, CDKN2C
3modulation by virus of host morphology or physiologyGO:01904811.1PDGFRA, MDM2, DMBT1, RB1, KDR, TP53
4cell cycle arrestGO:00705011.0RB1, CDKN2A, CDKN2B, CDKN2C, TP53
5innate immune responseGO:04508711.0PDGFRA, MDM2, DMBT1, EGFR, PTEN, LGALS3
6negative regulation of cell proliferationGO:00828511.0CDKN2A, CDKN2B, CDKN2C, PTEN, TP53
7Ras protein signal transductionGO:00726511.0RB1, CDKN2A, CDK2, TP53
8phosphatidylinositol-mediated signalingGO:04801511.0PDGFRA, MDM2, EGFR, PTEN
9negative regulation of phosphorylationGO:04232610.9CDKN2A, CDKN2B, CDKN2C
10negative regulation of G1/S transition of mitotic cell cycleGO:200013410.9PTEN, CDKN2B, RB1
11fibroblast growth factor receptor signaling pathwayGO:00854310.9PDGFRA, MDM2, EGFR, PTEN
12positive regulation of fibroblast proliferationGO:04814610.9CDK4, EGFR, PDGFRA
13Fc-epsilon receptor signaling pathwayGO:03809510.9PTEN, EGFR, MDM2, PDGFRA
14negative regulation of epithelial cell proliferationGO:05068010.9PTEN, CDKN2B, RB1
15regulation of cyclin-dependent protein serine/threonine kinase activityGO:00007910.8CDKN2B, CDKN2C, PTEN
16epidermal growth factor receptor signaling pathwayGO:00717310.8PDGFRA, MDM2, EGFR, PTEN
17negative regulation of apoptotic processGO:04306610.8TP53, PTEN, KDR, EGFR, MDM2
18DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:00697710.7MDM2, CDK2, TP53
19positive regulation of epithelial cell differentiationGO:03085810.7CDKN2B, DMBT1
20mitotic G1 DNA damage checkpointGO:03157110.6CDK2, TP53
21positive regulation of ERK1 and ERK2 cascadeGO:07037410.6KDR, EGFR, PDGFRA
22replicative senescenceGO:09039910.6TP53, CDKN2A
23response to drugGO:04249310.5MGMT, MDM2, IGFBP2, CDK4
24neurotrophin TRK receptor signaling pathwayGO:04801110.3PTEN, EGFR, MDM2, PDGFRA

Molecular functions related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00551511.4TP53, PDGFRA, MDM2, DMBT1, RB1, EGFR
2protein kinase bindingGO:01990110.9CDKN2A, CDKN2B, CDKN2C, PTEN, TP53
3cyclin-dependent protein serine/threonine kinase inhibitor activityGO:00486110.8CDKN2C, CDKN2B, CDKN2A
4transmembrane receptor protein tyrosine kinase activityGO:00471410.8KDR, EGFR, PDGFRA
5vascular endothelial growth factor bindingGO:03808510.7PDGFRA, KDR
6MDM2/MDM4 family protein bindingGO:09737110.6TP53, CDKN2A
7p53 bindingGO:00203910.6MDM2, CDKN2A, TP53
8receptor signaling protein tyrosine kinase activityGO:00471610.6KDR, EGFR
9vascular endothelial growth factor-activated receptor activityGO:00502110.5KDR, PDGFRA
10enzyme bindingGO:01989910.3TP53, PTEN, EGFR, MDM2

Products for genes affiliated with Oligodendroglioma

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Sources for Oligodendroglioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet