MCID: OLG002
MIFTS: 55

Oligodendroglioma malady

Rare diseases, Neuronal diseases, Cancer diseases categories

Aliases & Classifications for Oligodendroglioma

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Sources:
9Disease Ontology, 41NIH Rare Diseases, 11DISEASES, 43Novoseek, 47Orphanet, 22GTR, 60UMLS, 33MeSH, 55SNOMED-CT, 38NCIt, 61UMLS via Orphanet
See all sources

Oligodendroglioma, Aliases & Descriptions:

Name: Oligodendroglioma 9 41 11 43 47 22 60
Oligodendroglial Neoplasm 9 60
Well Differentiated Oligodendroglioma 60
 
Anaplastic Oligodendroglioma 60
Oligodendroglial Tumors 43
Oligodendroglial Tumor 9


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

47
oligodendroglioma:
Inheritance: Not applicable; Age of onset: All ages


External Ids:

Disease Ontology9 DOID:3181
MeSH33 D009837
NCIt38 C3288
Orphanet47 251627
UMLS via Orphanet61 C0028945

Summaries for Oligodendroglioma

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Wikipedia:63 Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the... more...

MalaCards based summary: Oligodendroglioma, also known as oligodendroglial neoplasm, is related to oligoastrocytoma and mixed glioma. An important gene associated with Oligodendroglioma is IDH2 (isocitrate dehydrogenase 2 (NADP+), mitochondrial), and among its related pathways are Inhibition of Ribosome Biogenesis by p14(ARF) and TP53 network. The compounds sodium bisulfite and sunitinib have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial, and related mouse phenotypes are pigmentation and normal.

Related Diseases for Oligodendroglioma

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Diseases in the Oligodendroglioma family:

Adult Oligodendroglioma

Diseases related to Oligodendroglioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 148)
idRelated DiseaseScoreTop Affiliating Genes
1oligoastrocytoma31.5MGMT, GFAP
2mixed glioma30.8GFAP, PDGFRA
3brain cancer30.3GFAP, EGFR
4pilocytic astrocytoma30.1MGMT, GFAP, PTEN, LGALS3, CDK4
5gliosarcoma30.1CDK4, GFAP, PTEN
6sarcoma30.1PDGFRA, KDR, MDM2, CDK4
7rhabdomyosarcoma30.1PDGFRA, CDK4, MDM2
8medulloblastoma30.0CDKN2B, CDK4, PDGFRA, GFAP, MGMT
9pituitary adenoma30.0MGMT, CDK4, CDKN2B, LGALS3
10ependymoma29.9EGFR, MGMT, GFAP, PDGFRA, CDKN2B, MDM2
11adenoma29.6LGALS3, CDKN2A, MGMT, CDK4, CDKN2C
12anaplastic oligodendroglioma29.2MGMT, GFAP, PTEN, KDR, LGALS3, PDGFRA
13leukemia29.1CDKN2C, CDKN2B, MGMT, CDK4, IDH2, KDR
14astrocytoma29.0GFAP, MGMT, PDGFRA, MDM2, CDKN2A, EGFR
15breast cancer29.0PTEN, KDR, MDM2, EGFR, CDK4, LGALS3
16glioblastoma28.4MDM2, CDKN2A, CDK4, CDKN2B, EGFR, PDGFRA
17melanoma28.3MGMT, PTEN, LGALS3, CDKN2B, CDK4, CDKN2A
18glioblastoma multiforme28.0EGFR, CDKN2B, CDK4, CDKN2A, MDM2, PDGFRA
19cerebritis10.5
20chondroma10.5PDGFRA
21dysembryoplastic neuroepithelial tumor10.4
22spinal cord oligodendroglioma10.4
23teratoma10.4
24burkitt lymphoma10.4CDKN2B, CDKN2C
25parathyroid adenoma10.3CDKN2C, LGALS3
26endotheliitis10.3
27connective tissue benign neoplasm10.3MDM2, CDK4
28hemangioblastoma10.3GFAP, KDR
29dedifferentiated liposarcoma10.3CDK4, MDM2
30myxoid liposarcoma10.3CDK4, MDM2
31mixed oligodendroglioma-astrocytoma10.3
32adult oligodendroglioma10.3
33central neurocytoma10.3
34brain oligodendroglioma10.3
35gliomatosis cerebri10.3PTEN, GFAP
36gemistocytic astrocytoma10.3PTEN, GFAP
37rhabdomyosarcoma 2, alveolar10.3MDM2, CDK4
38angiosarcoma10.3PDGFRA, KDR
39pleomorphic adenoma10.3MDM2, GFAP
40chordoma10.3LGALS3, PDGFRA, GFAP
41neuronitis10.3
42childhood oligodendroglioma10.3
43myelodysplastic syndrome10.2CDKN2C, CDKN2B, PDGFRA
44malignant fibroxanthoma10.2CDK4, MDM2
45corpus callosum oligodendroglioma10.2
46mixed astrocytoma-ependymoma-oligodendroglioma10.2
47extraventricular neurocytoma10.2
48ganglioneuroma10.2GFAP, PTEN
49cerebral cavernous malformations-110.2KDR, PTEN
50thyroid carcinoma, papillary10.2PTEN, LGALS3

Graphical network of the top 20 diseases related to Oligodendroglioma:



Diseases related to oligodendroglioma

Symptoms for Oligodendroglioma

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Drugs & Therapeutics for Oligodendroglioma

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Drug clinical trials:

Search ClinicalTrials for Oligodendroglioma

Search NIH Clinical Center for Oligodendroglioma

Genetic Tests for Oligodendroglioma

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Genetic tests related to Oligodendroglioma:

id Genetic test Affiliating Genes
1 Oligodendroglioma22

Anatomical Context for Oligodendroglioma

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MalaCards organs/tissues related to Oligodendroglioma:

31
Brain, Spinal cord, Endothelial, Bone, Bone marrow, Temporal lobe, Breast, Cerebellum, Myeloid, B cells, Parietal lobe, Medulla oblongata, Tongue, Pineal, Pituitary

Animal Models for Oligodendroglioma or affiliated genes

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MGI Mouse Phenotypes related to Oligodendroglioma:

35 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011867.8PTEN, PDGFRA, MDM2, CDKN2A, EGFR
2MP:00028737.6EGFR, MDM2, PDGFRA, KDR, PTEN, GFAP
3MP:00030127.5MGMT, KDR, PDGFRA, MDM2, CDKN2A, CDKN2B
4MP:00053677.4PTEN, LGALS3, PDGFRA, MDM2, CDKN2C, CDK4
5MP:00053887.3PTEN, KDR, LGALS3, PDGFRA, CDKN2A, CDKN2C
6MP:00053707.2PTEN, KDR, MDM2, CDKN2A, CDK4, EGFR
7MP:00053917.2GFAP, PTEN, KDR, CDKN2A, CDK4, EGFR
8MP:00053907.1PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
9MP:00053817.0GFAP, PTEN, LGALS3, PDGFRA, MDM2, CDKN2A
10MP:00053807.0PTEN, KDR, PDGFRA, MDM2, CDKN2A, CDK4
11MP:00053856.9GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
12MP:00053696.9GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
13MP:00053796.9MGMT, PTEN, PDGFRA, CDKN2A, CDKN2C, CDK4
14MP:00053866.9GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
15MP:00053896.7PTEN, LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C
16MP:00020066.6EGFR, MGMT, PTEN, PDGFRA, MDM2, CDKN2A
17MP:00053786.5GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
18MP:00107716.4PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
19MP:00053976.3PDGFRA, LGALS3, KDR, PTEN, MDM2, CDKN2A
20MP:00036316.3GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
21MP:00053876.1LGALS3, KDR, PTEN, GFAP, PDGFRA, MDM2
22MP:00053846.1GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
23MP:00053766.0KDR, PTEN, GFAP, MGMT, LGALS3, PDGFRA
24MP:00107685.6LGALS3, KDR, PTEN, GFAP, MGMT, PDGFRA

Publications for Oligodendroglioma

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Articles related to Oligodendroglioma:

(show top 50)    (show all 625)
idTitleAuthorsYear
1
Efficacy and patient-reported outcomes with dose-intense temozolomide in patients with newly diagnosed pure and mixed anaplastic oligodendroglioma: a phase II multicenter study. (25534576)
2015
2
Occipital anaplastic oligodendroglioma with multiple organ metastases after a short clinical course: a case report and literature review. (24447608)
2014
3
Multiple sclerosis and oligodendroglioma: an exceptional association. (25180114)
2014
4
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors. (24162809)
2014
5
Short-term survivors in glioblastomas with oligodendroglioma component: a clinical study of 186 Chinese patients from a single institution. (24264532)
2014
6
A case of oligodendroglioma with prominent neuronal differentiation. (24054724)
2013
7
Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience. (23681562)
2013
8
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and I+-KG. (24252742)
2013
9
1p19q co-deleted oligodendroglioma metastatic to bone. (23073167)
2013
10
BMP Signaling Induces Astrocytic Differentiation of * Clinically-derived Oligodendroglioma Propagating Cells. (24269952)
2013
11
1p/19q codeletion and IDH1/2 mutation identified a subtype of anaplastic oligoastrocytomas with prognosis as favorable as anaplastic oligodendrogliomas. (23486687)
2013
12
Pitfalls of conservative treatments of multiple probable cerebral cavernous malformations (CCMs): clinicopathological features of CCMs coexisting with vasculogenic mimicry in an anaplastic oligodendroglioma. (24337536)
2013
13
iTRAQ-based quantitative proteomic analysis for identification of oligodendroglioma biomarkers related with loss of heterozygosity on chromosomal arm 1p. (23041135)
2012
14
Rare synchronous association of vestibular schwannoma and indolent insular oligodendroglioma in a patient without neurofibromatosis: controversial issue of timing for surgical treatment of asymptomatic low-grade gliomas. (23180968)
2012
15
Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report. (21569607)
2011
16
Supratentorial clear cell ependymoma mimicking oligodendroglioma : case report and review of the literature. (22102956)
2011
17
Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. (20236756)
2010
18
Non-stem cell origin for oligodendroglioma. (21156288)
2010
19
Identification of genetic alterations by multiple ligation-dependent probe amplification (MLPA) analysis in oligodendrogliomas]. (19448956)
2009
20
Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis. (19558288)
2009
21
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. (17438529)
2007
22
Oligodendroglioma with neurocytic differentiation versus atypical extraventricular neurocytoma: a case report of unusual pathologic findings of a spinal cord tumor. (17039400)
2007
23
Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy. (16084959)
2005
24
Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina. (16023538)
2005
25
Spinal epidural metastasis of cerebral oligodendroglioma. (12728479)
2003
26
Tumour necrosis and microvascular proliferation are associated with 9p deletion and CDKN2A alterations in 1p/19q-deleted oligodendrogliomas. (14507338)
2003
27
Allelic losses in oligodendroglial and oligodendroglioma-like neoplasms: analysis using microsatellite repeats and polymerase chain reaction. (14632576)
2003
28
Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. (12456321)
2003
29
Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. (12525516)
2003
30
Oligodendroglioma. (14585228)
2003
31
CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans. (12635659)
2002
32
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. (11443623)
2001
33
The prognostic significance of DNA topoisomerase II-alpha (Ki-S1), p21/Cip-1, and p27/Kip-1 protein immunoexpression in oligodendrogliomas. (11419973)
2001
34
New perspectives for the diagnosis and treatment of oligodendroglioma. (12113102)
2001
35
Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells. (11589429)
2001
36
Oligodendroglioma: HMB-45 positivity using catalyzed signal amplification method: an immunohistochemical (HMB-45, CD31, p53, Mib-1) and ultrastructural study. (11277413)
2001
37
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression. (11591848)
2001
38
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. (11303620)
2000
39
Evaluation of cell proliferation, epidermal growth factor receptor, and bcl-2 immunoexpression as prognostic factors for patients with World Health Organization grade 2 oligodendroglioma. (10679656)
2000
40
Glial fibrillary acidic protein and its fragments discriminate astrocytoma from oligodendroglioma. (10344289)
1999
41
Clinicohistological study of oligodendroglioma and oligoastrocytoma. (9384800)
1997
42
The ultrastructure of oligodendroglioma: personal experience and the review of the literature. (9812424)
1996
43
Recurrent oligodendroglioma diagnosed with 11C-L-methionine and PET: a case report. (8467848)
1993
44
Oligodendroglioma of the fourth ventricle with intracranial and spinal oligodendrogliomatosis: a case report. (1388833)
1992
45
Characterization of a cell line derived from a human oligodendroglioma. (1329795)
1992
46
Oligodendroglioma--a case presentation. (2308753)
1990
47
Primary oligodendroglioma of the lateral ventricle. (2406943)
1990
48
Oligodendroglioma arising in heterotopic brain tissue of the soft palate and nasopharynx. (3605491)
1987
49
Spinal dissemination following operation on cerebral oligodendroglioma. (878921)
1977
50
Intracerebral oligodendroglioma with metastatic involvement of the spinal cord. Case report. (5120009)
1971

Variations for Oligodendroglioma

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Cosmic variations for Oligodendroglioma:

7 (show all 273)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
143945TP53central nervous system,brain,glioma,NS3
211084TP53central nervous system,brain,glioma,NS3
343903TP53central nervous system,brain,glioma,oligodendroglioma3
444169TP53central nervous system,brain,glioma,NS3
510834TP53central nervous system,brain,glioma,NS3
610912TP53central nervous system,brain,glioma,NS3
710758TP53central nervous system,brain,glioma,NS3
843833TP53central nervous system,brain,glioma,NS3
911498TP53central nervous system,brain,glioma,NS3
1044226TP53central nervous system,brain,glioma,NS3
1110867TP53central nervous system,brain,glioma,NS3
1210645TP53central nervous system,brain,glioma,NS3
1344204TP53central nervous system,brain,glioma,NS3
1444271TP53central nervous system,brain,glioma,NS3
1545045TP53central nervous system,brain,glioma,NS3
1610731TP53central nervous system,brain,glioma,NS3
1710739TP53central nervous system,brain,glioma,NS3
1811066TP53central nervous system,brain,glioma,NS3
1910808TP53central nervous system,brain,glioma,NS3
2044092TP53central nervous system,brain,glioma,NS3
2111305TP53central nervous system,brain,glioma,NS3
2243714TP53central nervous system,brain,glioma,oligodendroglioma3
2310718TP53central nervous system,brain,glioma,NS3
2444964TP53central nervous system,brain,glioma,oligodendroglioma3
2543606TP53central nervous system,brain,glioma,NS3
2610690TP53central nervous system,brain,glioma,NS3
2744219TP53central nervous system,brain,glioma,oligodendroglioma3
2810742TP53central nervous system,brain,glioma,NS3
2943900TP53central nervous system,brain,glioma,NS3
3010790TP53central nervous system,brain,glioma,NS3
3144224TP53central nervous system,brain,glioma,oligodendroglioma3
3210863TP53central nervous system,brain,glioma,NS3
3344221TP53central nervous system,brain,glioma,NS3
3411059TP53central nervous system,brain,glioma,NS3
3510701TP53central nervous system,brain,glioma,NS3
3643708TP53central nervous system,brain,glioma,oligodendroglioma3
3743651TP53central nervous system,brain,glioma,NS3
3845368TP53central nervous system,brain,glioma,NS3
3944613TP53central nervous system,brain,glioma,NS3
4011210TP53central nervous system,brain,glioma,NS3
4144877TP53central nervous system,brain,glioma,NS3
4210935TP53central nervous system,brain,glioma,NS3
4343555TP53central nervous system,brain,glioma,NS3
4410771TP53central nervous system,brain,glioma,NS3
4510889TP53central nervous system,brain,glioma,NS3
4644525TP53central nervous system,brain,glioma,NS3
4710988TP53central nervous system,brain,glioma,NS3
4810659TP53central nervous system,brain,glioma,NS3
4910667TP53central nervous system,brain,glioma,NS3
5043739TP53central nervous system,brain,glioma,NS3
516932TP53central nervous system,brain,glioma,NS3
5243970TP53central nervous system,brain,glioma,NS3
5345796TP53central nervous system,brain,glioma,NS3
5410704TP53central nervous system,brain,glioma,NS3
5543755TP53central nervous system,brain,glioma,oligodendroglioma3
5644571TP53central nervous system,brain,glioma,NS3
5711250TP53central nervous system,brain,glioma,NS3
5810810TP53central nervous system,brain,glioma,oligodendroglioma3
5987196TP53central nervous system,brain,glioma,oligodendroglioma3
6011218TP53central nervous system,brain,glioma,NS3
6110660TP53central nervous system,brain,glioma,NS3
6244310TP53central nervous system,brain,glioma,oligodendroglioma3
6310662TP53central nervous system,brain,glioma,NS3
6443923TP53central nervous system,brain,glioma,NS3
6544327TP53central nervous system,brain,glioma,oligodendroglioma3
6611089TP53central nervous system,brain,glioma,NS3
6710687TP53central nervous system,brain,glioma,NS3
6844633TP53central nervous system,brain,glioma,NS3
6944057TP53central nervous system,brain,glioma,NS3
7011071TP53central nervous system,brain,glioma,NS3
7110794TP53central nervous system,brain,glioma,NS3
7248817TP53central nervous system,brain,glioma,NS3
7344249TP53central nervous system,brain,glioma,oligodendroglioma3
7443565TP53central nervous system,brain,glioma,NS3
7511392TP53central nervous system,brain,glioma,NS3
7610779TP53central nervous system,brain,glioma,NS3
7744637TP53central nervous system,brain,glioma,NS3
7810656TP53central nervous system,brain,glioma,oligodendroglioma3
7910648TP53central nervous system,brain,glioma,NS3
8010728TP53central nervous system,brain,glioma,NS3
8110726TP53central nervous system,brain,glioma,oligodendroglioma3
8243767TP53central nervous system,brain,glioma,NS3
8311087TP53central nervous system,brain,glioma,NS3
8411462TP53central nervous system,brain,glioma,NS3
855128PTENcentral nervous system,brain,glioma,oligodendroglioma3
865243PTENcentral nervous system,brain,glioma,NS3
875212PTENcentral nervous system,brain,glioma,NS3
885114PTENcentral nervous system,brain,glioma,oligodendroglioma3
895193PTENcentral nervous system,brain,glioma,oligodendroglioma3
905043PTENcentral nervous system,brain,glioma,NS3
913967199PTENcentral nervous system,brain,glioma,NS3
925253PTENcentral nervous system,brain,glioma,NS3
935089PTENcentral nervous system,brain,glioma,NS3
945113PTENcentral nervous system,brain,glioma,NS3
955137PTENcentral nervous system,brain,glioma,NS3
96163810PTENcentral nervous system,brain,glioma,NS3
975127PTENcentral nervous system,brain,glioma,oligodendroglioma3
985051PTENcentral nervous system,brain,glioma,NS3
995036PTENcentral nervous system,brain,glioma,NS3
1005185PTENcentral nervous system,brain,glioma,NS3
1015269PTENcentral nervous system,brain,glioma,NS3
1023967200PTENcentral nervous system,brain,glioma,NS3
1035097PTENcentral nervous system,brain,glioma,oligodendroglioma3
1045109PTENcentral nervous system,brain,glioma,oligodendroglioma3
1055186PTENcentral nervous system,brain,glioma,NS3
1065275PTENcentral nervous system,brain,glioma,NS3
1075040PTENcentral nervous system,brain,glioma,oligodendroglioma3
1085268PTENcentral nervous system,brain,glioma,NS3
10912458PIK3CAcentral nervous system,brain,glioma,NS3
110754PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
111775PIK3CAcentral nervous system,brain,glioma,NS3
11213570PIK3CAcentral nervous system,brain,glioma,NS3
113776PIK3CAcentral nervous system,brain,glioma,NS3
114219808PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
115746PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
116304027PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
1171041479PIK3CAcentral nervous system,brain,glioma,NS3
118767PIK3CAcentral nervous system,brain,glioma,NS3
1196147PIK3CAcentral nervous system,brain,glioma,NS3
12027377PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
121249139PIK3CAcentral nervous system,brain,glioma,NS3
12212463PIK3CAcentral nervous system,brain,glioma,NS3
123764PIK3CAcentral nervous system,brain,glioma,NS3
12437035PIK3CAcentral nervous system,brain,glioma,oligodendroglioma3
12512584PIK3CAcentral nervous system,brain,glioma,NS3
12612591PIK3CAcentral nervous system,brain,glioma,NS3
12712459PIK3CAcentral nervous system,brain,glioma,NS3
128760PIK3CAcentral nervous system,brain,glioma,NS3
129751PIK3CAcentral nervous system,brain,glioma,NS3
130763PIK3CAcentral nervous system,brain,glioma,NS3
13128750IDH1central nervous system,brain,glioma,NS3
13288208IDH1central nervous system,brain,glioma,oligodendroglioma3
13351384IDH1central nervous system,brain,glioma,NS3
13428746IDH1central nervous system,brain,glioma,NS3
1351169216IDH1central nervous system,brain,glioma,oligodendroglioma3
13641293IDH1central nervous system,brain,glioma,NS3
13741292IDH1central nervous system,brain,glioma,NS3
13841294IDH1central nervous system,brain,glioma,NS3
13928749IDH1central nervous system,brain,glioma,NS3
14028748IDH1central nervous system,brain,glioma,NS3
14128747IDH1central nervous system,brain,glioma,NS3
14241291IDH1central nervous system,brain,glioma,NS3
14321687EGFRcentral nervous system,brain,glioma,NS3
14421690EGFRcentral nervous system,brain,glioma,NS3
1451169666EGFRcentral nervous system,brain,glioma,oligodendroglioma3
14621686EGFRcentral nervous system,brain,glioma,oligodendroglioma3
1471451549EGFRcentral nervous system,brain,glioma,NS3
14834166EGFRcentral nervous system,brain,glioma,oligodendroglioma3
14922555EGFRcentral nervous system,brain,glioma,oligodendroglioma3
15035752EGFRcentral nervous system,brain,glioma,NS3
15113979EGFRcentral nervous system,brain,glioma,NS3
15221683EGFRcentral nervous system,brain,glioma,NS3
153303951CICcentral nervous system,brain,glioma,oligodendroglioma3
154303952CICcentral nervous system,brain,glioma,oligodendroglioma3
1551716365CICcentral nervous system,brain,glioma,oligodendroglioma3
1561681078CICcentral nervous system,brain,glioma,NS3
157132817CICcentral nervous system,brain,glioma,oligodendroglioma3
1581737905CICcentral nervous system,brain,glioma,NS3
159132677CICcentral nervous system,brain,glioma,oligodendroglioma3
160303956CICcentral nervous system,brain,glioma,NS3
1611235464CICcentral nervous system,brain,glioma,oligodendroglioma3
16286077IDH2central nervous system,brain,glioma,NS3
16341296IDH2central nervous system,brain,glioma,oligodendroglioma3
164144496IDH2central nervous system,brain,glioma,NS3
16534090IDH2central nervous system,brain,glioma,NS3
16634039IDH2central nervous system,brain,glioma,oligodendroglioma3
16733733IDH2central nervous system,brain,glioma,NS3
16833732IDH2central nervous system,brain,glioma,oligodendroglioma3
16941295IDH2central nervous system,brain,glioma,oligodendroglioma3
17033731IDH2central nervous system,brain,glioma,NS3
171303991TANC1central nervous system,brain,glioma,oligodendroglioma3
1721669313TANC1central nervous system,brain,glioma,NS3
173303993TANC1central nervous system,brain,glioma,oligodendroglioma3
1741669315TANC1central nervous system,brain,glioma,NS3
175303992TANC1central nervous system,brain,glioma,oligodendroglioma3
1761130BRAFcentral nervous system,brain,glioma,oligodendroglioma3
177467BRAFcentral nervous system,brain,glioma,NS3
1781131BRAFcentral nervous system,brain,glioma,oligodendroglioma3
179476BRAFcentral nervous system,brain,glioma,NS3
18013029PTPN11central nervous system,brain,glioma,NS3
18124612PTPN11central nervous system,brain,glioma,NS3
18213035PTPN11central nervous system,brain,glioma,NS3
18313993PTPN11central nervous system,brain,glioma,NS3
1841684815PDGFRAcentral nervous system,brain,glioma,NS3
18513348PDGFRAcentral nervous system,brain,glioma,NS3
18643059PDGFRAcentral nervous system,brain,glioma,NS3
1871348446ANK3central nervous system,brain,glioma,NS3
188132658ANK3central nervous system,brain,glioma,oligodendroglioma3
18913373TRIM33central nervous system,brain,glioma,NS3
19013372TRIM33central nervous system,brain,glioma,NS3
191304034RIMS2central nervous system,brain,glioma,oligodendroglioma3
192200344RIMS2central nervous system,brain,glioma,oligodendroglioma3
19313324MTORcentral nervous system,brain,glioma,NS3
1941662881MTORcentral nervous system,brain,glioma,NS3
19520404ATMcentral nervous system,brain,glioma,oligodendroglioma3
196304070ATMcentral nervous system,brain,glioma,oligodendroglioma3
197132886KRAScentral nervous system,brain,glioma,NS3
198518KRAScentral nervous system,brain,glioma,oligodendroglioma3
199132728MSH6central nervous system,brain,glioma,oligodendroglioma3
20013341MSH6central nervous system,brain,glioma,NS3
201133832CDKN2Acentral nervous system,brain,glioma,oligodendroglioma3
20213272CDKN2Acentral nervous system,brain,glioma,NS3
203580NRAScentral nervous system,brain,glioma,NS3
20424850NRAScentral nervous system,brain,glioma,oligodendroglioma3
20513366STYK1central nervous system,brain,glioma,NS3
2061716195STYK1central nervous system,brain,glioma,NS3
2071266238SMARCA4central nervous system,brain,glioma,NS3
208303247SMARCA4central nervous system,brain,glioma,NS3
209684ERBB2central nervous system,brain,glioma,NS3
21039419FGFR3central nervous system,brain,glioma,NS3
21113323FLT1central nervous system,brain,glioma,NS3
212132692GFPT2central nervous system,brain,glioma,oligodendroglioma3
21313320EPHB6central nervous system,brain,glioma,NS3
2141681167ELSPBP1central nervous system,brain,glioma,NS3
21513318EPHA6central nervous system,brain,glioma,NS3
216679210EPHA8central nervous system,brain,glioma,NS3
217244789GRB7central nervous system,brain,glioma,NS3
21813327GUCY2Fcentral nervous system,brain,glioma,NS3
2191681227IL4I1central nervous system,brain,glioma,NS3
22013331INSRRcentral nervous system,brain,glioma,NS3
22113332IRAK1central nervous system,brain,glioma,NS3
2221716243TFDP1central nervous system,brain,glioma,NS3
2231080380TINAGcentral nervous system,brain,glioma,NS3
224132701HDAC2central nervous system,brain,glioma,oligodendroglioma3
22527395HNF1Acentral nervous system,brain,glioma,oligodendroglioma3
2261679282KARScentral nervous system,brain,glioma,NS3
2271675009EHMT1central nervous system,brain,glioma,NS3
2281371355TSHRcentral nervous system,brain,glioma,NS3
2291246131BLKcentral nervous system,brain,glioma,NS3
23013374TYRO3central nervous system,brain,glioma,NS3
231917933ANKRD30Acentral nervous system,brain,glioma,NS3
23239766ACLYcentral nervous system,brain,glioma,NS3
233304047TRPM1central nervous system,brain,glioma,oligodendroglioma3
2341670399CBLBcentral nervous system,brain,glioma,NS3
2351200426CDH16central nervous system,brain,glioma,NS3
2361671363TMEM154central nervous system,brain,glioma,NS3
237304058DSG4central nervous system,brain,glioma,oligodendroglioma3
238132682CTTNBP2central nervous system,brain,glioma,oligodendroglioma3
239551917YY1central nervous system,brain,glioma,NS3
240443415ZAP70central nervous system,brain,glioma,NS3
241417011CREBBPcentral nervous system,brain,glioma,NS3
2421676183KAT5central nervous system,brain,glioma,NS3
2431668765RAB10central nervous system,brain,glioma,NS3
24439437RAC2central nervous system,brain,glioma,NS3
245132757RBL2central nervous system,brain,glioma,oligodendroglioma3
2461045668SMARCC1central nervous system,brain,glioma,NS3
2471673725PTPRN2central nervous system,brain,glioma,NS3
248132790ZFP36L2central nervous system,brain,glioma,oligodendroglioma3
24913355PTK2central nervous system,brain,glioma,NS3
250989762SOCS6central nervous system,brain,glioma,NS3
2511111027ROR2central nervous system,brain,glioma,NS3
2521668574SLC35F3central nervous system,brain,glioma,NS3
253132768SLC9A6central nervous system,brain,glioma,oligodendroglioma3
2541374208SMAD3central nervous system,brain,glioma,NS3
25513363SIK1central nervous system,brain,glioma,NS3
25695220RUNX1T1central nervous system,brain,glioma,NS3
2571265475SH2D3Ccentral nervous system,brain,glioma,NS3
2581088134PRPS1L1central nervous system,brain,glioma,NS3
259692METcentral nervous system,brain,glioma,oligodendroglioma3
260132770TCEA2central nervous system,brain,glioma,oligodendroglioma3
26154432TAF4Bcentral nervous system,brain,glioma,NS3
26226928LIN28Acentral nervous system,brain,glioma,NS3
2631716185LETM1central nervous system,brain,glioma,NS3
2641212907KSR1central nervous system,brain,glioma,NS3
265420536MUC7central nervous system,brain,glioma,NS3
2661680324NOL4central nervous system,brain,glioma,NS3
267485575PMS2P11central nervous system,brain,glioma,NS3
2681470691POTEMcentral nervous system,brain,glioma,NS3
269475213ZNF845central nervous system,brain,glioma,NS3
27013349PDK2central nervous system,brain,glioma,NS3
271132739NUP188central nervous system,brain,glioma,oligodendroglioma3
2721267026SUMF2central nervous system,brain,glioma,NS3
27321289TEX14central nervous system,brain,glioma,NS3

Expression for genes affiliated with Oligodendroglioma

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Search GEO for disease gene expression data for Oligodendroglioma.

Pathways for genes affiliated with Oligodendroglioma

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Pathways related to Oligodendroglioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.4CDKN2A, MDM2
2
Show member pathways
9.4CDKN2A, MDM2
3
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation58
9.2CDKN2A, CDK4, CDKN2B
49.2KDR, PDGFRA, EGFR
5
Show member pathways
9.2KDR, PDGFRA, EGFR
69.0GFAP, LGALS3, CDK4, EGFR
79.0CDKN2B, CDK4, PTEN
8
Show member pathways
8.9CDKN2B, CDK4, CDKN2C, CDKN2A
9
Show member pathways
8.9PTEN, MDM2, CDK4
10
Show member pathways
Prostate Cancer36
Integrated Cancer pathway36
Steroid Biosynthesis36
8.9CDK4, MDM2, PTEN
118.8MDM2, CDKN2A, CDK4, CDKN2B
12
Show member pathways
8.7KDR, PDGFRA, MDM2, EGFR
138.7KDR, PDGFRA, MDM2, EGFR
14
Show member pathways
Translation Non genomic rapid action of Androgen Receptor58
8.7PTEN, MDM2, EGFR
158.7EGFR, MDM2, PTEN
168.7EGFR, MDM2, PTEN
17
Show member pathways
Signal transduction PTEN pathway58
8.7EGFR, MDM2, PTEN
188.6CDK4, CDKN2A, MDM2, KDR
19
Show member pathways
DNA damage response (only ATM dependent)36
Wnt Signaling Pathway and Pluripotency36
8.6PTEN, MDM2, CDKN2A
208.6CDKN2A, MDM2, PTEN
218.6PDGFRA, CDKN2A, CDKN2C, CDK4, CDKN2B
22
Show member pathways
8.5EGFR, CDK4, CDKN2A, MDM2
23
Show member pathways
Cell cycle36
8.5MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
24
Show member pathways
8.5MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
25
Show member pathways
8.5MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
26
Show member pathways
8.5MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
278.5MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
28
Show member pathways
PLK2 and PLK4 events36
Polo-like kinase signaling events in the cell cycle36
8.4EGFR, CDKN2B, MDM2, PTEN
29
Show member pathways
8.3EGFR, PDGFRA, KDR, PTEN
30
Show member pathways
Integrin-mediated cell adhesion36
Focal Adhesion36
8.3EGFR, PDGFRA, KDR, PTEN
318.3EGFR, CDK4, MDM2, PTEN
32
Show member pathways
8.3EGFR, MDM2, PDGFRA, PTEN
33
Show member pathways
8.3PTEN, PDGFRA, MDM2, EGFR
34
Show member pathways
8.2MGMT, MDM2, CDKN2A, CDKN2C, CDK4
35
Show member pathways
DNA damage response36
8.2CDK4, CDKN2A, MDM2, PTEN
36
Show member pathways
8.0GFAP, PTEN, PDGFRA, MDM2, EGFR
378.0PTEN, PDGFRA, MDM2, CDKN2B, EGFR
38
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
39
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
407.7PTEN, PDGFRA, MDM2, CDKN2A, EGFR
417.7PTEN, PDGFRA, MDM2, CDK4, CDKN2B, EGFR
427.5PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
437.5PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
44
Show member pathways
7.3GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2B
45
Show member pathways
7.3PTEN, KDR, PDGFRA, MDM2, CDKN2A, EGFR
46
Show member pathways
7.2KDR, PDGFRA, MDM2, CDKN2A, CDKN2C, CDK4
477.0PTEN, PDGFRA, MDM2, CDKN2A, CDK4, CDKN2B
486.8MGMT, PTEN, PDGFRA, MDM2, CDKN2A, CDK4
49
Show member pathways
Signaling Pathways in Glioblastoma36
6.7EGFR, PTEN, PDGFRA, MDM2, CDKN2A, CDKN2C
50
Show member pathways
6.1GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A

Compounds for genes affiliated with Oligodendroglioma

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Compounds related to Oligodendroglioma according to GeneCards Suite gene sharing:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1sodium bisulfite439.3MGMT, CDKN2B, CDKN2A
2sunitinib43 49 1211.2KDR, PDGFRA, EGFR
37,12-dimethylbenz(a)anthracene439.1MGMT, MDM2, CDKN2A
45-methylcytosine43 2410.0MGMT, CDKN2A, CDKN2B
5geldanamycin43 49 59 1212.0KDR, EGFR, CDK4, MDM2
6bcnu438.9MGMT, EGFR, CDKN2A, GFAP
75-methylthioadenosine438.9CDKN2B, CDKN2A, EGFR
8flavopiridol43 129.8CDK4, MDM2, EGFR, CDKN2A
9hematoxylin438.7PTEN, GFAP, LGALS3, CDKN2A
10carboplatin43 49 1210.6EGFR, CDK4, MDM2, KDR, MGMT
11irinotecan43 49 1210.6MDM2, MGMT, CDKN2A, EGFR
12tgf beta1438.6PTEN, KDR, PDGFRA, CDK4, CDKN2B
13temozolomide43 129.5MGMT, CDKN2A, EGFR
14camptothecin43 59 1210.5CDKN2A, MGMT, MDM2, KDR, CDK4
15egcg438.4EGFR, CDK4, CDKN2A, KDR, MGMT
16thymidine43 249.4MGMT, CDK4, MDM2, GFAP, PDGFRA, KDR
17thymidylate438.4CDK4, MGMT, MDM2, EGFR, CDKN2A
18trastuzumab43 49 1210.3PTEN, MDM2, CDK4, EGFR, KDR
19gefitinib43 49 1210.3EGFR, CDK4, MDM2, KDR, PTEN
20glycogen43 249.3CDK4, MDM2, LGALS3, PTEN, GFAP
21phosphotyrosine438.3EGFR, CDK4, KDR, PTEN, PDGFRA
22imatinib43 49 1210.2PTEN, PDGFRA, KDR, MDM2, EGFR
23vincristine43 49 1210.2MDM2, PTEN, MGMT, CDKN2A
24pd 98,059438.1GFAP, PTEN, EGFR, CDK4, CDKN2B, MDM2
255-aza-2deoxycytidine438.1CDKN2B, CDKN2A, PTEN, MGMT, MDM2
26ly294002438.1PTEN, KDR, MDM2, EGFR, CDK4
27dexamethasone43 49 28 1211.0MDM2, KDR, CDKN2A, GFAP, MGMT, CDK4
28mg 13243 599.0PTEN, MDM2, KDR, CDKN2A, EGFR
29rapamycin437.9EGFR, PDGFRA, PTEN, KDR, CDK4, MDM2
30cycloheximide437.7EGFR, CDK4, PTEN, CDKN2A, MDM2, GFAP
31testosterone43 59 24 1210.7PTEN, GFAP, CDK4, EGFR, CDKN2A, MDM2
32arginine437.6CDK4, GFAP, PTEN, KDR, LGALS3, MDM2
33phosphatidylinositol437.6PDGFRA, LGALS3, KDR, CDK4, PTEN, EGFR
34threonine437.5PTEN, GFAP, CDKN2B, CDK4, CDKN2C, CDKN2A
35oligonucleotide437.4CDK4, PTEN, LGALS3, PDGFRA, MDM2, CDKN2A
36nitric oxide43 24 129.3CDK4, CDKN2A, PTEN, KDR, LGALS3, MDM2
375fluorouracil437.2KDR, EGFR, CDK4, CDKN2A, MDM2, MGMT
38doxorubicin43 49 129.2CDK4, MGMT, CDKN2A, MDM2, KDR, PTEN
39agar437.2GFAP, PTEN, KDR, LGALS3, MDM2, CDKN2A
40cysteine437.1MGMT, GFAP, PTEN, KDR, LGALS3, CDK4
41tyrosine437.1MDM2, GFAP, PTEN, KDR, LGALS3, PDGFRA
42progesterone43 28 59 24 1211.0CDKN2A, MGMT, GFAP, PTEN, LGALS3, MDM2
43paclitaxel43 49 128.9CDKN2A, EGFR, MGMT, GFAP, PTEN, KDR
44genistein43 28 59 2 24 1211.9KDR, MDM2, GFAP, MGMT, EGFR, PTEN
45cisplatin43 49 59 129.6LGALS3, EGFR, CDKN2A, MDM2, KDR, PTEN
46serine436.6PTEN, GFAP, CDKN2B, CDK4, CDKN2C, CDKN2A
47retinoic acid43 247.4CDKN2B, CDKN2A, PDGFRA, LGALS3, KDR, PTEN
48paraffin436.3PDGFRA, CDKN2A, CDK4, EGFR, MDM2, LGALS3
49vegf436.3CDK4, CDKN2A, KDR, MGMT, GFAP, PTEN
50estrogen436.0EGFR, CDKN2B, CDK4, CDKN2A, MDM2, PDGFRA

GO Terms for genes affiliated with Oligodendroglioma

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Cellular components related to Oligodendroglioma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:00166049.4CDKN2A, MDM2
2cytosolGO:00058297.1GFAP, PTEN, MDM2, CDKN2A, CDKN2C, CDK4
3cytoplasmGO:00057376.4GFAP, PTEN, LGALS3, PDGFRA, MDM2, CDKN2A
4nucleusGO:00056345.5EGFR, MGMT, PTEN, KDR, LGALS3, PDGFRA

Biological processes related to Oligodendroglioma according to GeneCards Suite gene sharing:

(show all 31)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of protein serine/threonine kinase activityGO:007190110.2CDKN2C, CDKN2B
2negative regulation of cell cycle arrestGO:00711579.9MDM2, CDK4
3negative regulation of phosphorylationGO:00423269.7CDKN2B, CDKN2C, CDKN2A
4positive regulation of fibroblast proliferationGO:00481469.6EGFR, CDK4, PDGFRA
5positive regulation of DNA replicationGO:00457409.6EGFR, PDGFRA
6protein destabilizationGO:00316489.6CDKN2A, MDM2
7cell cycle arrestGO:00070509.6CDKN2B, CDKN2C, CDKN2A
8negative regulation of G1/S transition of mitotic cell cycleGO:020001349.5CDKN2B, PTEN
9long-term synaptic potentiationGO:00602919.5GFAP, PTEN
10positive regulation of DNA repairGO:00457399.5EGFR, MGMT
11peptidyl-tyrosine phosphorylationGO:00181089.5KDR, PDGFRA, EGFR
12positive regulation of ERK1 and ERK2 cascadeGO:00703749.5EGFR, PDGFRA, KDR
13positive regulation of cell migrationGO:00303359.5KDR, PDGFRA, EGFR
14G1/S transition of mitotic cell cycleGO:00000829.4CDK4, CDKN2C, CDKN2A
15extracellular matrix organizationGO:00301989.4PDGFRA, LGALS3, KDR, GFAP
16regulation of cyclin-dependent protein serine/threonine kinase activityGO:00000799.4PTEN, CDKN2C, CDKN2B
17protein autophosphorylationGO:00467779.4KDR, PDGFRA, EGFR
18platelet-derived growth factor receptor signaling pathwayGO:00480089.3PDGFRA, PTEN
19mitotic cell cycleGO:00002789.2CDKN2B, CDK4, CDKN2C, CDKN2A
20regulation of protein stabilityGO:00316478.9PTEN, CDKN2A
21learning or memoryGO:00076118.8EGFR, PTEN
22negative regulation of cell proliferationGO:00082858.8PTEN, CDKN2A, CDKN2C, CDKN2B
23phosphatidylinositol-mediated signalingGO:00480158.7PTEN, PDGFRA, MDM2, EGFR
24fibroblast growth factor receptor signaling pathwayGO:00085438.7EGFR, MDM2, PDGFRA, PTEN
25Fc-epsilon receptor signaling pathwayGO:00380958.7PTEN, PDGFRA, MDM2, EGFR
26response to drugGO:00424938.7MGMT, PTEN, MDM2, CDK4
27epidermal growth factor receptor signaling pathwayGO:00071738.7PTEN, PDGFRA, MDM2, EGFR
28neurotrophin TRK receptor signaling pathwayGO:00480118.7PTEN, PDGFRA, MDM2, EGFR
29negative regulation of apoptotic processGO:00430668.5EGFR, MDM2, KDR, PTEN
30innate immune responseGO:00450878.3EGFR, MDM2, PDGFRA, LGALS3, PTEN
31positive regulation of cell proliferationGO:00082847.9EGFR, PTEN, KDR, PDGFRA, MDM2, CDK4

Molecular functions related to Oligodendroglioma according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor bindingGO:00380859.8PDGFRA, KDR
2vascular endothelial growth factor-activated receptor activityGO:00050219.8PDGFRA, KDR
3cyclin-dependent protein serine/threonine kinase inhibitor activityGO:00048619.5CDKN2B, CDKN2C, CDKN2A
4receptor signaling protein tyrosine kinase activityGO:00047169.4EGFR, KDR
5transmembrane receptor protein tyrosine kinase activityGO:00047149.3KDR, PDGFRA, EGFR
6integrin bindingGO:00051789.3GFAP, KDR, EGFR
7platelet-derived growth factor receptor bindingGO:00051619.0PDGFRA, PTEN
8enzyme bindingGO:00198998.7EGFR, MDM2, PTEN
9protein kinase bindingGO:00199018.1EGFR, CDKN2B, CDKN2C, CDKN2A, PTEN
10protein bindingGO:00055156.1PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A

Products for genes affiliated with Oligodendroglioma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Oligodendroglioma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet