MCID: OLG002
MIFTS: 64

Oligodendroglioma malady

Rare diseases, Neuronal diseases, Cancer diseases categories
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Summaries for Oligodendroglioma

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65Wikipedia, 33MalaCards
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Wikipedia:65 Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the... more...

MalaCards: Oligodendroglioma, also known as oligodendroglial neoplasm, is related to oligoastrocytoma and anaplastic oligodendroglioma. An important gene associated with Oligodendroglioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Inhibition of Ribosome Biogenesis by p14(ARF) and TP53 network. The compounds sodium bisulfite and 7,12-dimethylbenz(a)anthracene have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial, and related mouse phenotypes are pigmentation and normal.

Aliases & Classifications for Oligodendroglioma

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Sources:
8Disease Ontology, 43NIH Rare Diseases, 22GTR, 10DISEASES, 45Novoseek, 49Orphanet, 62UMLS, 35MeSH, 58SNOMED-CT, 40NCIt, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

49
oligodendroglioma:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

oligodendroglioma 8 43 22 10 45 49 62
oligodendroglial neoplasm 8 62
oligodendroglial tumors 45
oligodendroglial tumor 8
oligodendroglioma nos 8


External Ids:

Disease Ontology8 DOID:3181
MeSH35 D009837
NCIt40 C3288
SNOMED-CT via Orphanet59 443936004, 73348003
UMLS via Orphanet63 C0028945

Related Diseases for Oligodendroglioma

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17GeneCards, 18GeneDecks
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Diseases in the Oligodendroglioma family:

Adult Oligodendroglioma

Diseases related to Oligodendroglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 151)
idRelated DiseaseScoreTop Affiliating Genes
1oligoastrocytoma31.0MGMT, GFAP
2anaplastic oligodendroglioma30.8LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C, CDK4
3astrocytoma30.4MGMT, DMBT1, GFAP, PTEN, KDR, LGALS3
4ependymoma30.4MGMT, GFAP, PDGFRA, MDM2, CDKN2B, EGFR
5pilocytic astrocytoma30.3MGMT, GFAP, PTEN, LGALS3, CDK4
6mixed glioma30.2GFAP, PDGFRA
7brain cancer30.1GFAP, EGFR
8meningioma30.1CDKN2B, CDKN2C, PTEN, GFAP
9leukemia30.1MGMT, KDR, PDGFRA, MDM2, CDKN2A, CDKN2C
10sarcoma30.1KDR, PDGFRA, MDM2, CDK4
11cerebral cavernous malformation29.9PTEN, KDR
12gliosarcoma29.9CDK4, PTEN, GFAP
13rhabdomyosarcoma29.9CDK4, MDM2, PDGFRA
14pituitary adenoma29.9CDKN2B, CDK4, LGALS3, MGMT
15adenoma29.8MGMT, LGALS3, CDKN2A, CDKN2C, CDK4
16medulloblastoma29.7MGMT, DMBT1, GFAP, PDGFRA, CDK4, CDKN2B
17breast cancer29.6PTEN, KDR, LGALS3, MDM2, CDK4, EGFR
18melanoma29.4KDR, LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C
19anaplastic astrocytoma29.3DMBT1, GFAP, PTEN, LGALS3, PDGFRA, MDM2
20glioblastoma multiforme29.3PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
21cerebritis10.5
22spinal cord oligodendroglioma10.4
23dysembryoplastic neuroepithelial tumor10.3
24teratoma10.3
25endotheliitis10.3
26mixed oligodendroglioma-astrocytoma10.2
27neuronitis10.2
28brain oligodendroglioma10.2
29adult oligodendroglioma10.2
30central neurocytoma10.2
31multiple sclerosis10.2
32diffuse astrocytoma10.2
33childhood oligodendroglioma10.2
34extraventricular neurocytoma10.2
35mixed astrocytoma-ependymoma-oligodendroglioma10.1
36clear cell ependymoma10.1
37arteriovenous malformation10.1
38hypoxia10.1
39chondroma10.1PDGFRA
40glomerulosclerosis, focal segmental, 610.1
41burkitt's lymphoma10.1CDKN2B, CDKN2C
42parathyroid adenoma10.1LGALS3, CDKN2C
43hemangioblastoma10.1KDR, GFAP
44dedifferentiated liposarcoma10.1MDM2, CDK4
45myxoid liposarcoma10.1CDK4, MDM2
46gliomatosis cerebri10.1PTEN, GFAP
47gemistocytic astrocytoma10.1PTEN, GFAP
48alveolar rhabdomyosarcoma10.1CDK4, MDM2
49angiosarcoma10.1KDR, PDGFRA
50pleomorphic adenoma10.1MDM2, GFAP

Graphical network of the top 20 diseases related to Oligodendroglioma:



Diseases related to oligodendroglioma

Symptoms for Oligodendroglioma

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Drugs & Therapeutics for Oligodendroglioma

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Sources:
42NIH Clinical Center, 6ClinicalTrials, 62UMLS, 41NDF-RT
See all sources

Drug clinical trials:

Search ClinicalTrials for Oligodendroglioma

Search NIH Clinical Center for Oligodendroglioma

Genetic Tests for Oligodendroglioma

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22GTR
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Genetic tests related to Oligodendroglioma:

id Genetic test Affiliating Genes
1 Oligodendroglioma22

Anatomical Context for Oligodendroglioma

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33MalaCards
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MalaCards organs/tissues related to Oligodendroglioma:

33
Brain, Spinal cord, Endothelial, Bone, Bone marrow, Temporal lobe, Breast, Tongue, Medulla oblongata, Pineal, Parietal lobe, B cells, Myeloid, Cerebellum, Pituitary

Animal Models for Oligodendroglioma or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Oligodendroglioma:

37 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011867.9PTEN, PDGFRA, MDM2, CDKN2A, EGFR
2MP:00028737.6EGFR, MDM2, PDGFRA, KDR, PTEN, GFAP
3MP:00030127.5MGMT, KDR, PDGFRA, MDM2, CDKN2A, CDKN2B
4MP:00053887.4PTEN, KDR, LGALS3, PDGFRA, CDKN2A, CDKN2C
5MP:00053867.4GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
6MP:00053707.3PTEN, KDR, MDM2, CDKN2A, CDK4, EGFR
7MP:00053917.3GFAP, PTEN, KDR, CDKN2A, CDK4, EGFR
8MP:00053907.1PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
9MP:00053797.1MGMT, PTEN, PDGFRA, CDKN2A, CDKN2C, CDK4
10MP:00053697.1GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
11MP:00053857.0GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
12MP:00053676.9DMBT1, PTEN, LGALS3, PDGFRA, MDM2, CDKN2C
13MP:00053896.9PTEN, LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C
14MP:00053806.8DMBT1, PTEN, KDR, PDGFRA, MDM2, CDKN2A
15MP:00053786.7GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
16MP:00053816.7DMBT1, GFAP, PTEN, LGALS3, PDGFRA, MDM2
17MP:00107716.5PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
18MP:00036316.5GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
19MP:00053976.5PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
20MP:00020066.3EGFR, MGMT, DMBT1, PTEN, PDGFRA, MDM2
21MP:00053875.8LGALS3, KDR, PTEN, GFAP, DMBT1, PDGFRA
22MP:00053845.8LGALS3, KDR, PTEN, GFAP, DMBT1, PDGFRA
23MP:00053765.7KDR, PTEN, GFAP, DMBT1, MGMT, LGALS3
24MP:00107685.3KDR, PTEN, GFAP, DMBT1, MGMT, LGALS3

Publications for Oligodendroglioma

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52PubMed
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Articles related to Oligodendroglioma:

(show top 50)    (show all 592)
idTitleAuthorsYear
1
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors. (24162809)
2014
2
Short-term survivors in glioblastomas with oligodendroglioma component: a clinical study of 186 Chinese patients from a single institution. (24264532)
2014
3
A case of oligodendroglioma with prominent neuronal differentiation. (24054724)
2013
4
Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience. (23681562)
2013
5
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and I+-KG. (24252742)
2013
6
1p19q co-deleted oligodendroglioma metastatic to bone. (23073167)
2013
7
BMP Signaling Induces Astrocytic Differentiation of * Clinically-derived Oligodendroglioma Propagating Cells. (24269952)
2013
8
Pitfalls of conservative treatments of multiple probable cerebral cavernous malformations (CCMs): clinicopathological features of CCMs coexisting with vasculogenic mimicry in an anaplastic oligodendroglioma. (24337536)
2013
9
Erratum to: Leukemia-like onset of bone marrow metastasis from anaplastic oligodendroglioma after 17A years of dormancy: an autopsy case report. (24036579)
2013
10
iTRAQ-based quantitative proteomic analysis for identification of oligodendroglioma biomarkers related with loss of heterozygosity on chromosomal arm 1p. (23041135)
2012
11
Rare synchronous association of vestibular schwannoma and indolent insular oligodendroglioma in a patient without neurofibromatosis: controversial issue of timing for surgical treatment of asymptomatic low-grade gliomas. (23180968)
2012
12
Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report. (21569607)
2011
13
Supratentorial clear cell ependymoma mimicking oligodendroglioma : case report and review of the literature. (22102956)
2011
14
Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. (20236756)
2010
15
Non-stem cell origin for oligodendroglioma. (21156288)
2010
16
Identification of genetic alterations by multiple ligation-dependent probe amplification (MLPA) analysis in oligodendrogliomas]. (19448956)
2009
17
Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis. (19558288)
2009
18
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. (17438529)
2007
19
Oligodendroglioma with neurocytic differentiation versus atypical extraventricular neurocytoma: a case report of unusual pathologic findings of a spinal cord tumor. (17039400)
2007
20
Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy. (16084959)
2005
21
Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina. (16023538)
2005
22
Spinal epidural metastasis of cerebral oligodendroglioma. (12728479)
2003
23
Tumour necrosis and microvascular proliferation are associated with 9p deletion and CDKN2A alterations in 1p/19q-deleted oligodendrogliomas. (14507338)
2003
24
Allelic losses in oligodendroglial and oligodendroglioma-like neoplasms: analysis using microsatellite repeats and polymerase chain reaction. (14632576)
2003
25
Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. (12456321)
2003
26
Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. (12525516)
2003
27
Oligodendroglioma. (14585228)
2003
28
CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans. (12635659)
2002
29
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. (11443623)
2001
30
The prognostic significance of DNA topoisomerase II-alpha (Ki-S1), p21/Cip-1, and p27/Kip-1 protein immunoexpression in oligodendrogliomas. (11419973)
2001
31
New perspectives for the diagnosis and treatment of oligodendroglioma. (12113102)
2001
32
Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells. (11589429)
2001
33
Oligodendroglioma: HMB-45 positivity using catalyzed signal amplification method: an immunohistochemical (HMB-45, CD31, p53, Mib-1) and ultrastructural study. (11277413)
2001
34
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression. (11591848)
2001
35
P18 tumor suppressor gene and progression of oligodendrogliomas to anaplasia. (10994011)
2000
36
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. (11303620)
2000
37
Evaluation of cell proliferation, epidermal growth factor receptor, and bcl-2 immunoexpression as prognostic factors for patients with World Health Organization grade 2 oligodendroglioma. (10679656)
2000
38
Glial fibrillary acidic protein and its fragments discriminate astrocytoma from oligodendroglioma. (10344289)
1999
39
Clinicohistological study of oligodendroglioma and oligoastrocytoma. (9384800)
1997
40
The ultrastructure of oligodendroglioma: personal experience and the review of the literature. (9812424)
1996
41
Recurrent oligodendroglioma diagnosed with 11C-L-methionine and PET: a case report. (8467848)
1993
42
Oligodendroglioma of the fourth ventricle with intracranial and spinal oligodendrogliomatosis: a case report. (1388833)
1992
43
Characterization of a cell line derived from a human oligodendroglioma. (1329795)
1992
44
Intramedullary "holocord" oligodendroglioma: case report. (1799150)
1991
45
Oligodendroglioma--a case presentation. (2308753)
1990
46
Primary oligodendroglioma of the lateral ventricle. (2406943)
1990
47
Oligodendroglioma arising in heterotopic brain tissue of the soft palate and nasopharynx. (3605491)
1987
48
Regulation of glycosphingolipid metabolism in mouse neuroblastoma and glioma cell lines. Comparison of glioma (oligodendroglioma-like) with neutroblastoma cell lines. (31364)
1979
49
Spinal dissemination following operation on cerebral oligodendroglioma. (878921)
1977
50
Intracerebral oligodendroglioma with metastatic involvement of the spinal cord. Case report. (5120009)
1971

Variations for Oligodendroglioma

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Expression for genes affiliated with Oligodendroglioma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Oligodendroglioma

Search GEO for disease gene expression data for Oligodendroglioma.

Pathways for genes affiliated with Oligodendroglioma

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Sources:
50PathCards, 53QIAGEN, 38NCBI BioSystems Database, 55Reactome, 60Thomson Reuters, 30KEGG, 57SinoBiological, 5Cell Signaling Technology, 51PharmGKB, 61Tocris Bioscience, 54R&D Systems
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Pathways related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CDKN2A, MDM2
2
Show member pathways
9.5CDKN2A, MDM2
3
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation60
9.4CDKN2A, CDK4, CDKN2B
49.2CDKN2B, CDK4, PTEN
5
Show member pathways
Prostate Cancer38
Integrated Cancer pathway38
Steroid Biosynthesis38
9.1CDK4, MDM2, PTEN
6
Show member pathways
9.1PTEN, MDM2, CDK4
7
Show member pathways
9.1CDKN2B, CDK4, CDKN2C, CDKN2A
88.9MDM2, CDKN2A, CDK4, CDKN2B
98.9KDR, PDGFRA, EGFR
10
Show member pathways
8.9KDR, PDGFRA, EGFR
118.9CDKN2A, MDM2, PTEN
12
Show member pathways
DNA damage response (only ATM dependent)38
Wnt Signaling Pathway and Pluripotency38
8.9PTEN, MDM2, CDKN2A
138.9CDK4, CDKN2A, MDM2, KDR
148.8GFAP, LGALS3, CDK4, EGFR
158.7PDGFRA, CDKN2A, CDKN2C, CDK4, CDKN2B
16
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
178.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
18
Show member pathways
Cell cycle38
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
19
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
20
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
218.6EGFR, MDM2, PTEN
228.6EGFR, MDM2, PTEN
23
Show member pathways
Signal transduction PTEN pathway60
8.6EGFR, MDM2, PTEN
24
Show member pathways
Translation Non genomic rapid action of Androgen Receptor60
8.6PTEN, MDM2, EGFR
25
Show member pathways
DNA damage response38
8.6CDK4, CDKN2A, MDM2, PTEN
268.5KDR, PDGFRA, MDM2, EGFR
27
Show member pathways
8.5KDR, PDGFRA, MDM2, EGFR
28
Show member pathways
8.5MGMT, MDM2, CDKN2A, CDKN2C, CDK4
29
Show member pathways
8.4EGFR, CDK4, CDKN2A, MDM2
30
Show member pathways
PLK2 and PLK4 events38
Polo-like kinase signaling events in the cell cycle38
8.3EGFR, CDKN2B, MDM2, PTEN
31
Show member pathways
Integrin-mediated cell adhesion38
Focal Adhesion38
8.3EGFR, PDGFRA, KDR, PTEN
32
Show member pathways
8.3EGFR, PDGFRA, KDR, PTEN
338.3EGFR, CDK4, MDM2, PTEN
34
Show member pathways
8.3EGFR, MDM2, PDGFRA, PTEN
35
Show member pathways
8.3PTEN, PDGFRA, MDM2, EGFR
36
Show member pathways
8.0GFAP, PTEN, PDGFRA, MDM2, EGFR
378.0PTEN, PDGFRA, MDM2, CDKN2B, EGFR
38
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
39
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
407.8PTEN, PDGFRA, MDM2, CDKN2A, EGFR
417.7PTEN, PDGFRA, MDM2, CDK4, CDKN2B, EGFR
427.6PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
437.6PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
44
Show member pathways
7.4PTEN, KDR, PDGFRA, MDM2, CDKN2A, EGFR
45
Show member pathways
7.4GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2B
467.2PTEN, PDGFRA, MDM2, CDKN2A, CDK4, CDKN2B
47
Show member pathways
7.1KDR, PDGFRA, MDM2, CDKN2A, CDKN2C, CDK4
487.0MGMT, PTEN, PDGFRA, MDM2, CDKN2A, CDK4
49
Show member pathways
Signaling Pathways in Glioblastoma38
6.9EGFR, PTEN, PDGFRA, MDM2, CDKN2A, CDKN2C
50
Show member pathways
6.3GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A

Compounds for genes affiliated with Oligodendroglioma

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Sources:
45Novoseek, 24HMDB, 51PharmGKB, 11DrugBank, 61Tocris Bioscience, 29IUPHAR, 3BitterDB
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Compounds related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1sodium bisulfite459.4CDKN2B, CDKN2A, MGMT
27,12-dimethylbenz(a)anthracene459.3MGMT, MDM2, CDKN2A
35-methylcytosine45 2410.1CDKN2B, CDKN2A, MGMT
4hematoxylin459.1GFAP, PTEN, LGALS3, CDKN2A
5sunitinib45 51 1110.9EGFR, PDGFRA, KDR
6tgf beta1458.9PTEN, KDR, PDGFRA, CDK4, CDKN2B
7bcnu458.8MGMT, GFAP, CDKN2A, EGFR
8camptothecin45 61 1110.8MGMT, KDR, MDM2, CDKN2A, CDK4
9geldanamycin45 51 61 1111.8KDR, MDM2, CDK4, EGFR
10flavopiridol45 119.7MDM2, CDKN2A, CDK4, EGFR
11thymidine45 249.6MGMT, GFAP, KDR, PDGFRA, MDM2, CDK4
12glycogen45 249.6GFAP, PTEN, LGALS3, MDM2, CDK4
135-methylthioadenosine458.6CDKN2A, CDKN2B, EGFR
14vincristine45 51 1110.5CDKN2A, MDM2, PTEN, MGMT
15irinotecan45 51 1110.5EGFR, CDKN2A, MDM2, MGMT
165-aza-2deoxycytidine458.5MGMT, PTEN, MDM2, CDKN2A, CDKN2B
17carboplatin45 51 1110.5EGFR, CDK4, MDM2, KDR, MGMT
18egcg458.4MGMT, KDR, CDKN2A, CDK4, EGFR
19thymidylate458.3MGMT, MDM2, CDKN2A, CDK4, EGFR
20trastuzumab45 51 1110.3PTEN, KDR, MDM2, CDK4, EGFR
21gefitinib45 51 1110.3PTEN, KDR, MDM2, CDK4, EGFR
22dexamethasone45 51 29 1111.3CDK4, CDKN2A, MDM2, KDR, GFAP, MGMT
23phosphotyrosine458.3PTEN, KDR, PDGFRA, CDK4, EGFR
24imatinib45 51 1110.2PTEN, KDR, PDGFRA, MDM2, EGFR
25pd 98,059458.2GFAP, PTEN, MDM2, CDK4, CDKN2B, EGFR
26mg 13245 619.1EGFR, CDKN2A, MDM2, KDR, PTEN
27ly294002458.0PTEN, KDR, MDM2, CDK4, EGFR
28arginine458.0GFAP, PTEN, KDR, LGALS3, MDM2, CDKN2A
29rapamycin458.0PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
30threonine457.9GFAP, PTEN, LGALS3, MDM2, CDKN2A, CDKN2C
31oligonucleotide457.9MGMT, PTEN, LGALS3, PDGFRA, MDM2, CDKN2A
32cycloheximide457.8GFAP, PTEN, MDM2, CDKN2A, CDK4, EGFR
33nitric oxide45 24 119.8MGMT, PTEN, KDR, LGALS3, MDM2, CDKN2A
34testosterone45 61 24 1110.8GFAP, PTEN, MDM2, CDKN2A, CDK4, EGFR
35phosphatidylinositol457.6PTEN, KDR, LGALS3, PDGFRA, MDM2, CDK4
365fluorouracil457.4MGMT, PTEN, KDR, MDM2, CDKN2A, CDK4
37doxorubicin45 51 119.4MGMT, PTEN, KDR, MDM2, CDKN2A, CDK4
38agar457.3GFAP, PTEN, KDR, LGALS3, MDM2, CDKN2A
39progesterone45 29 61 24 1111.2MGMT, GFAP, PTEN, LGALS3, MDM2, CDKN2A
40tyrosine457.1GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
41paclitaxel45 51 119.1MGMT, GFAP, PTEN, KDR, MDM2, CDKN2A
42genistein45 29 61 3 24 1112.1MGMT, GFAP, PTEN, KDR, MDM2, CDKN2A
43cysteine457.1MGMT, DMBT1, GFAP, PTEN, KDR, LGALS3
44calcium45 51 24 1110.0MGMT, DMBT1, GFAP, PTEN, LGALS3, PDGFRA
45cisplatin45 51 61 119.8MGMT, GFAP, PTEN, KDR, LGALS3, MDM2
46retinoic acid45 247.6MGMT, GFAP, PTEN, KDR, LGALS3, PDGFRA
47paraffin456.5CDK4, CDKN2A, MDM2, PDGFRA, LGALS3, KDR
48vegf456.5MGMT, GFAP, PTEN, KDR, LGALS3, PDGFRA
49estrogen456.2EGFR, MGMT, CDKN2B, CDK4, CDKN2A, MDM2
50serine456.2KDR, PTEN, GFAP, DMBT1, LGALS3, MDM2

GO Terms for genes affiliated with Oligodendroglioma

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Sources:
16Gene Ontology
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Cellular components related to Oligodendroglioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:0166049.5CDKN2A, MDM2
2cytosolGO:0058297.5GFAP, PTEN, MDM2, CDKN2A, CDKN2C, CDK4
3cytoplasmGO:0057376.0LGALS3, PTEN, GFAP, DMBT1, PDGFRA, MDM2
4nucleusGO:0056345.8EGFR, MGMT, PTEN, KDR, LGALS3, PDGFRA

Biological processes related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of protein serine/threonine kinase activityGO:07190110.2CDKN2B, CDKN2C
2positive regulation of epithelial cell differentiationGO:03085810.0CDKN2B, DMBT1
3negative regulation of cell cycle arrestGO:07115710.0CDK4, MDM2
4negative regulation of phosphorylationGO:0423269.8CDKN2A, CDKN2C, CDKN2B
5protein destabilizationGO:0316489.7CDKN2A, MDM2
6negative regulation of G1/S transition of mitotic cell cycleGO:20001349.7CDKN2B, PTEN
7long-term synaptic potentiationGO:0602919.7GFAP, PTEN
8cell cycle arrestGO:0070509.7CDKN2B, CDKN2C, CDKN2A
9regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.7CDKN2B, CDKN2C, PTEN
10G1/S transition of mitotic cell cycleGO:0000829.6CDKN2A, CDKN2C, CDK4
11extracellular matrix organizationGO:0301989.6GFAP, KDR, LGALS3, PDGFRA
12platelet-derived growth factor receptor signaling pathwayGO:0480089.5PDGFRA, PTEN
13mitotic cell cycleGO:0002789.4CDKN2B, CDK4, CDKN2C, CDKN2A
14positive regulation of fibroblast proliferationGO:0481469.4PDGFRA, CDK4, EGFR
15positive regulation of DNA replicationGO:0457409.3EGFR, PDGFRA
16peptidyl-tyrosine phosphorylationGO:0181089.3KDR, PDGFRA, EGFR
17positive regulation of DNA repairGO:0457399.3EGFR, MGMT
18positive regulation of ERK1 and ERK2 cascadeGO:0703749.3EGFR, PDGFRA, KDR
19positive regulation of cell migrationGO:0303359.2KDR, PDGFRA, EGFR
20regulation of protein stabilityGO:0316479.2PTEN, CDKN2A
21protein autophosphorylationGO:0467779.2EGFR, PDGFRA, KDR
22negative regulation of cell proliferationGO:0082859.1PTEN, CDKN2A, CDKN2C, CDKN2B
23response to drugGO:0424939.0CDK4, MDM2, PTEN, MGMT
24viral processGO:0160329.0DMBT1, KDR, PDGFRA, MDM2
25learning or memoryGO:0076118.7EGFR, PTEN
26phosphatidylinositol-mediated signalingGO:0480158.7EGFR, MDM2, PDGFRA, PTEN
27fibroblast growth factor receptor signaling pathwayGO:0085438.7PTEN, PDGFRA, MDM2, EGFR
28Fc-epsilon receptor signaling pathwayGO:0380958.7PTEN, PDGFRA, MDM2, EGFR
29epidermal growth factor receptor signaling pathwayGO:0071738.7EGFR, MDM2, PDGFRA, PTEN
30neurotrophin TRK receptor signaling pathwayGO:0480118.6PTEN, PDGFRA, MDM2, EGFR
31negative regulation of apoptotic processGO:0430668.5PTEN, KDR, MDM2, EGFR
32positive regulation of cell proliferationGO:0082848.0EGFR, CDK4, MDM2, PDGFRA, KDR, PTEN
33innate immune responseGO:0450877.9DMBT1, PTEN, LGALS3, PDGFRA, MDM2, EGFR

Molecular functions related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor bindingGO:0380859.9PDGFRA, KDR
2vascular endothelial growth factor-activated receptor activityGO:0050219.8KDR, PDGFRA
3cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.6CDKN2B, CDKN2C, CDKN2A
4platelet-derived growth factor receptor bindingGO:0051619.2PDGFRA, PTEN
5receptor signaling protein tyrosine kinase activityGO:0047169.2KDR, EGFR
6transmembrane receptor protein tyrosine kinase activityGO:0047149.1KDR, PDGFRA, EGFR
7integrin bindingGO:0051789.0EGFR, KDR, GFAP
8enzyme bindingGO:0198998.6EGFR, MDM2, PTEN
9protein kinase bindingGO:0199018.2PTEN, CDKN2A, CDKN2C, CDKN2B, EGFR
10protein bindingGO:0055155.9DMBT1, PTEN, KDR, LGALS3, PDGFRA, MDM2

Products for genes affiliated with Oligodendroglioma

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Sources for Oligodendroglioma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet