MCID: OLG002
MIFTS: 56

Oligodendroglioma malady

Neuronal, Cancer categories

Summaries for Oligodendroglioma

Sources:
64Wikipedia, 33MalaCards
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Wikipedia:64 Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the... more...

MalaCards: Oligodendroglioma, also known as oligodendroglial neoplasm, is related to anaplastic oligodendroglioma and astrocytoma. An important gene associated with Oligodendroglioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Rho Family GTPases and Pathways in cancer. The compounds retinoic acid and vegf have been mentioned in the context of this disorder. Related mouse phenotypes are mortality/aging and immune system.

Aliases & Classifications for Oligodendroglioma

Sources:
8Disease Ontology, 43NIH Rare Diseases, 22GTR, 10DISEASES, 45Novoseek, 49Orphanet, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer
Anatomical: Neuronal


Characteristics (Orphanet epidemiological data):

49
oligodendroglioma:
Inheritance: Sporadic; Age of onset: Variable


Aliases & Descriptions:

oligodendroglioma 8 43 22 10 45 49 61
oligodendroglial neoplasm 8 61
oligodendroglial tumors 45
oligodendroglial tumor 8
oligodendroglioma nos 8


External Ids:

Disease Ontology8 DOID:3181
MeSH35 D009837
NCIt40 C3288

Related Diseases for Oligodendroglioma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases in the Oligodendroglioma family:

adult oligodendroglioma

Diseases related to Oligodendroglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 201)
idRelated DiseaseScoreTop Affiliating Genes
1anaplastic oligodendroglioma31.4LGALS3, PTEN, KDR, GFAP, OLIG2, OLIG1
2astrocytoma31.0TP53, LGALS3, PTEN, KDR, GFAP, OLIG2
3oligoastrocytoma30.8GFAP, MGMT
4dysembryoplastic neuroepithelial tumor30.5OLIG2
5ependymoma30.5GFAP, CDKN2B, EGFR, RB1, MDM2, MGMT
6teratoma30.4GFAP
7anaplastic astrocytoma30.3TP53, LGALS3, PTEN, GFAP, OLIG2, OLIG1
8pilocytic astrocytoma30.3LGALS3, PTEN, GFAP, OLIG2, CDK4, MGMT
9central neurocytoma30.3GFAP, OLIG2
10brain cancer30.2EGFR, MDM2, MGMT
11acute leukemia30.0CDKN2C, CDKN2B, IGFBP2, STMN1
12adenoma29.8TP53, LGALS3, CDKN2C, CDK2, CDK4, CDKN2A
13acute lymphoblastic leukemia, childhood29.8CDK2, CDK4, CDKN2B, CDKN2A, MDM2
14gliosarcoma29.8PTEN, GFAP, CDK4
15anaplastic ependymoma29.8PTEN, GFAP, MDM2
16neurofibromatosis29.8PDGFRA
17t-cell leukemia29.8LGALS3, CDK2, CDK4, STMN1
18cerebral cavernous malformation29.8PTEN, KDR
19brain oligodendroglioma10.6
20spinal cord oligodendroglioma10.5
21adult oligodendroglioma10.4
22childhood oligodendroglioma10.3
23anaplastic oligoastrocytoma10.3
24mixed oligodendroglioma-astrocytoma10.3
25diffuse astrocytoma10.3
26clear cell ependymoma10.2
27extraventricular neurocytoma10.2
28arteriovenous malformation10.1
29ovarian cystic teratoma10.1
30mixed astrocytoma-ependymoma-oligodendroglioma10.1
31hypoxia10.1
32glomerulosclerosis, focal segmental, 610.1
33granular cell tumor10.1
34cerebral angioma10.0
35brain sarcoma10.0
36pleomorphic xanthoastrocytoma10.0
37melanoma10.0TP53, LGALS3, PTEN, KDR, CDKN2C, CDK2
38squamous cell carcinoma10.0TP53, LGALS3, PTEN, KDR, CDK2, CDK4
39glioblastoma multiforme10.0TP53, PTEN, KDR, GFAP, CDK4, CDKN2B
40adenocarcinoma10.0TP53, LGALS3, PTEN, KDR, CDK2, CDK4
41malignant glioma10.0TP53, PTEN, KDR, GFAP, OLIG2, CDK4
42leukemia10.0TP53, KDR, OLIG2, CDKN2C, CDK2, CDK4
43non-small cell lung carcinoma10.0TP53, PTEN, KDR, CDKN2C, CDK2, CDK4
44breast cancer10.0TP53, LGALS3, PTEN, KDR, CDKN2C, CDK2
45hepatocellular carcinoma10.0TP53, PTEN, KDR, CDKN2C, CDK2, CDK4
46ovarian cancer10.0TP53, PTEN, KDR, CDKN2C, CDK2, CDK4
47retinoblastoma10.0TP53, GFAP, CDKN2C, CDK2, CDK4, CDKN2B
48colorectal cancer10.0TP53, LGALS3, PTEN, KDR, CDK2, CDKN2A
49burkitt's lymphoma10.0TP53, LGALS3, CDKN2C, CDK2, CDK4, CDKN2B
50squamous cell carcinoma of the head and neck10.0TP53, LGALS3, KDR, CDK2, CDK4, CDKN2B

Graphical network of the top 20 diseases related to Oligodendroglioma:



Diseases related to oligodendroglioma

Clinical Features for Oligodendroglioma

Drugs & Therapeutics for Oligodendroglioma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Oligodendroglioma

Drug clinical trials:

Search ClinicalTrials for Oligodendroglioma

Search NIH Clinical Center for Oligodendroglioma

Search CenterWatch for Oligodendroglioma

Genetic Tests for Oligodendroglioma

Sources:
22GTR
See all sources

Genetic tests related to Oligodendroglioma:

id Genetic test Affiliating Genes
1 Oligodendroglioma22

Anatomical Context for Oligodendroglioma

Animal Models for Oligodendroglioma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

MGI Mouse Phenotypes related to Oligodendroglioma:

37 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:001076811.6CDKN2C, TP53, LGALS3, PTEN, GFAP, CDK2
2MP:000538711.5CDKN2A, CDKN2B, CDK4, CDK2, CDKN2C, PTEN
3MP:000538411.5CDKN2C, CDK2, OLIG2, CDK4, CDKN2A, EGFR
4MP:000200611.4CDK4, MGMT, MDM2, DMBT1, RB1, EGFR
5MP:000538511.4TP53, CDKN2C, RB1, STMN1, CDK4, IGFBP2
6MP:000539711.4PDGFRA, CDK4, MDM2, RB1, EGFR, CDKN2C
7MP:000537811.3EGFR, CDK4, PDGFRA, MDM2, TP53, PTEN
8MP:000536911.3CDK2, OLIG2, RB1, GFAP, KDR, CDKN2A
9MP:001077111.3KDR, CDKN2C, CDK4, CDK2, CDKN2B, CDKN2A
10MP:000538111.2CDKN2A, LGALS3, EGFR, GFAP, CDK4, DMBT1
11MP:000537011.1IGFBP2, CDKN2A, CDK4, CDK2, KDR, PTEN
12MP:000537611.1CDKN2C, CDK4, GFAP, DMBT1, MGMT, PDGFRA
13MP:000301211.1MGMT, PDGFRA, MDM2, RB1, EGFR, CDKN2A
14MP:000538911.1PDGFRA, CDKN2C, CDK2, TP53, EGFR, CDKN2B
15MP:000537911.1MGMT, PDGFRA, CDKN2C, RB1, CDKN2A, CDKN2B
16MP:000363111.0CDK4, OLIG1, OLIG2, GFAP, LGALS3
17MP:000538811.0LGALS3, OLIG2, TP53, PTEN, KDR, CDKN2C
18MP:000536710.9DMBT1, EGFR, LGALS3
19MP:000287310.8MDM2, IGFBP2, EGFR, TP53, PTEN, KDR
20MP:000538210.7TP53, PTEN, RB1, MDM2, PDGFRA, EGFR
21MP:000538010.7DMBT1
22MP:000539010.6LGALS3, OLIG2, PDGFRA, RB1
23MP:000538610.6OLIG2, MDM2, RB1, CDKN2A, CDK4, CDKN2C
24MP:000539110.6EGFR, GFAP

Publications for Oligodendroglioma

Sources:
51PubMed
See all sources

Articles related to Oligodendroglioma:

(show top 50)    (show all 602)
idTitleAuthorsYear
1
Metachronous, multicentric glioma of pilocytic astrocytoma with oligodendroglioma-like component and oligodendroglioma through distinct genetic aberrations. (23082883)
2013
2
Diffuse anaplastic leptomeningeal oligodendrogliomatosis mimicking neurosarcoidosis. (23914328)
2013
3
Anaplastic oligodendroglioma in an adolescent with Lynch syndrome. (23255519)
2013
4
iTRAQ-based quantitative proteomic analysis for identification of oligodendroglioma biomarkers related with loss of heterozygosity on chromosomal arm 1p. (23041135)
2012
5
Evaluation of the expression of C-kit (CD117) in ependymomas and oligodendrogliomas. (22846208)
2012
6
Unusual intracranial spread of anaplastic oligodendroglioma. (22891021)
2012
7
Pilocytic astrocytoma with abundant oligodendroglioma-like component. (22203030)
2012
8
DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma. (22718548)
2012
9
CIC and FUBP1 mutations in oligodendroglioma. (22596010)
2012
10
Clinicopathological features in the recurrence of oligodendroglioma and diffuse astrocytoma. (22648019)
2012
11
Pleomorphic xanthoastrocytoma and oligodendroglioma: collision of 2 morphologically and genetically distinct anaplastic components. (21214337)
2011
12
Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology. (21069360)
2011
13
EGFR expression stratifies oligodendroglioma behavior. (21839716)
2011
14
Oligodendroglioma arising in a mature cystic ovarian teratoma in a child. (20863158)
2010
15
Caveolin 1 expression independently predicts shorter survival in oligodendrogliomas. (19287309)
2009
16
Gene expression analyses of grade II gliomas and identification of rPTPbeta/zeta as a candidate oligodendroglioma marker. (18003890)
2008
17
De novo formation of large arteriovenous shunting and a vascular nidus mimicking an arteriovenous malformation within an anaplastic oligodendroglioma: treatment with embolization and resection. (19035725)
2008
18
Hemin rescues adrenodoxin, heme a and cytochrome oxidase activity in frataxin-deficient oligodendroglioma cells. (17499976)
2007
19
Neuro-oncology: oligodendroglioma and molecular markers. (17166792)
2007
20
Clinicopathologic aspects of 1p/19q loss and the diagnosis of oligodendroglioma. (17284109)
2007
21
Prognostic value of CXCL12 expression in 40 low-grade oligodendrogliomas and oligoastrocytomas. (16760646)
2006
22
Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling. (16550607)
2006
23
High-dose chemotherapy with stem cell rescue as initial therapy for anaplastic oligodendroglioma: long-term follow-up. (16524945)
2006
24
Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina. (16023538)
2005
25
Oligodendroglioma in the cervical spinal cord of a dog. (15347828)
2004
26
Selective expression of a subset of neuronal genes in oligodendroglioma with chromosome 1p loss. (14997935)
2004
27
Metastatic anaplastic oligodendroglioma simulating acute leukemia. A case report. (12789933)
2003
28
Molecular markers that identify human astrocytomas and oligodendrogliomas. (11939588)
2002
29
Oligodendroglioma: pathology and molecular biology. (12453646)
2002
30
Oligodendroglioma arising in a sacrococcygeal immature teratoma. (12068154)
2002
31
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. (11443623)
2001
32
New perspectives for the diagnosis and treatment of oligodendroglioma. (12113102)
2001
33
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression. (11591848)
2001
34
Promoter hypermethylation and homozygous deletion of the p14ARF and p16INK4a genes in oligodendrogliomas. (11307615)
2001
35
Combined oligodendroglioma/pleomorphic xanthoastrocytoma: a probable collision tumor: case report. (11383742)
2001
36
Multiple sclerosis and oligodendroglioma. (11548988)
2001
37
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. (11303620)
2000
38
Long-term outcome of low-grade oligodendroglioma and mixed glioma. (10751254)
2000
39
Vascular endothelial growth factor (VEGF) likely contributes to oligodendroglioma angiogenesis. (10208285)
1999
40
Antiapoptotic Bcl-2 family protein expression increases with progression of oligodendroglioma. (10547558)
1999
41
Glycolipid markers of astrocytomas and oligodendrogliomas. (10604750)
1999
42
Oligodendroglioma with signet-ring cell morphology: a case report with an immunohistochemical and ultrastructural study. (9589479)
1998
43
Oligodendroglioma: the ultrastructural spectrum. (8191647)
1994
44
Giant sized oligodendroglioma of posterior fossa. (1460319)
1992
45
Balo's concentric sclerosis: a variant of multiple sclerosis associated with oligodendroglioma. (2601832)
1989
46
Primary intraventricular oligodendroglioma--report of two cases. (3454696)
1986
47
Subcellular localization of hyaluronate synthetase in oligodendroglioma cells. (6425282)
1984
48
Oligodendroglioma with sarcomatous features. (6793899)
1981
49
Extracranial metastases of oligodendroglioma: report of a case and review of the literature. (7242888)
1981
50
Arteriovenous malformation and oligodendroglioma. Case report. (1141977)
1975

Genetic Variations for Oligodendroglioma

Expression for genes affiliated with Oligodendroglioma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Oligodendroglioma

Search GEO for disease gene expression data for Oligodendroglioma.

Pathways for genes affiliated with Oligodendroglioma

Sources:
52QIAGEN, 30KEGG, 38NCBI BioSystems Database, 53R&D Systems, 54Reactome, 4Cell Signaling Technology, 12EMD Millipore, 56SinoBiological, 60Tocris Bioscience
See all sources

Pathways related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 65)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
11.1CDKN2B, CDKN2A, EGFR, RB1, STMN1, MDM2
210.9PDGFRA, MDM2, RB1, EGFR, CDKN2A, CDKN2B
310.9CDKN2A, MGMT, PDGFRA, MDM2, PTEN, CDK2
410.8CDK2, PTEN, TP53, CDK4, CDKN2B, EGFR
5
Hide members
10.8KDR, PDGFRA, MDM2, RB1, CDKN2A, PTEN
610.8KDR, PTEN, PDGFRA, MDM2, EGFR, CDK4
710.8TP53, PTEN, KDR, CDK2, CDK4, EGFR
810.8RB1, CDKN2C, CDK4, CDKN2B, PDGFRA, TP53
9
Hide members
10.8CDK4, CDKN2C, CDKN2B, CDKN2A, RB1, MDM2
10
Hide members
10.8MGMT, CDKN2C, CDK4, CDKN2A, MDM2, RB1
11
Hide members
10.8RB1, CDKN2A, CDKN2B, CDKN2C, CDK4, CDK2
12
Hide members
10.8PDGFRA, CDKN2C, MDM2, RB1, CDKN2B, CDK2
1310.8LGALS3, TP53, CDK2, GFAP, EGFR, CDK4
1410.8MDM2, PTEN, STMN1, CDKN2A, EGFR, TP53
1510.8MDM2, RB1, CDKN2A, CDK4, CDK2, TP53
16
Hide members
10.8MDM2, TP53, CDK2, CDK4, CDKN2A, PTEN
17
Transcription P53 signaling pathway
Hide members
10.8TP53, CDKN2A, KDR, CDK2, CDK4, MDM2
1810.8CDK4, RB1, MDM2, PTEN, CDK2, EGFR
19
Hide members
10.7KDR, EGFR, MDM2, PTEN, PDGFRA, TP53
20
Hide members
10.7TP53, PDGFRA, PTEN, KDR, EGFR, MDM2
21
Hide members
10.7PDGFRA, STMN1, CDKN2B, CDK4, CDK2, TP53
22
Hide members
10.7MDM2, RB1, EGFR, CDKN2A, TP53, CDK4
2310.7RB1, CDKN2B, TP53, PTEN, CDK2, CDK4
24
Hide members
10.7CDKN2A, CDKN2C, CDK2, TP53, RB1, MDM2
25
Hide members
10.7MDM2, RB1, CDK4, CDK2, PTEN, TP53
26
Hide members
10.7PDGFRA, MDM2, EGFR, GFAP, PTEN
27
Cell cycle Cell cycle (generic schema)
Hide members
10.7RB1, CDKN2A, CDKN2B, CDK4, CDK2
28
Hide members
10.7PDGFRA, RB1, EGFR, PTEN, KDR
29
Hide members
10.7MGMT, MDM2, CDK4, CDK2, RB1
3010.7TP53, PTEN, CDKN2A, RB1, MDM2
31
Hide members
10.7MDM2, CDK4, CDK2, PTEN, RB1
3210.7MDM2, RB1, PTEN, TP53, EGFR
33
Hide members
10.7TP53, CDK4, CDK2, PTEN, RB1
34
Hide members
10.6CDKN2A, MDM2, PTEN, TP53
35
Hide members
10.6PTEN, EGFR, MDM2, TP53
3610.6PTEN, EGFR, RB1, MDM2
3710.6MGMT, TP53, CDK2, CDK4
3810.6TP53, CDKN2A, RB1, MDM2
3910.6CDK4, CDK2, TP53, MDM2
40
Hide members
10.6RB1, CDK4, PTEN, CDK2
41
Hide members
10.6PTEN, IGFBP2, MDM2, TP53
42
Hide members
10.6PDGFRA, KDR, MDM2
4310.6CDKN2A, MDM2, TP53
4410.6MDM2, CDKN2A, TP53
4510.6CDK4, CDK2, TP53
4610.6CDK2, CDK4, RB1
4710.6MDM2, CDK2, TP53
4810.6RB1, KDR, CDK2
4910.6RB1, CDK2
5010.6RB1, CDK2

Compounds for genes affiliated with Oligodendroglioma

Sources:
45Novoseek, 24HMDB, 50PharmGKB, 60Tocris Bioscience, 11DrugBank, 29IUPHAR, 2BitterDB
See all sources

Compounds related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 174)
idCompoundScoreTop Affiliating Genes
1retinoic acid45 2412.6CDKN2A, PTEN, KDR, GFAP, OLIG2, IGFBP2
2vegf4511.5TP53, LGALS3, KDR, GFAP, CDK2, CDK4
3cisplatin45 50 60 1114.5CDK2, GFAP, KDR, PTEN, LGALS3, TP53
4progesterone45 60 29 11 2415.5CDK2, CDK4, CDKN2A, IGFBP2, EGFR, STMN1
5tyrosine4511.4PTEN, LGALS3, IGFBP2, EGFR, RB1, STMN1
6paclitaxel45 50 1113.4CDK2, GFAP, KDR, PTEN, MDM2, STMN1
7doxorubicin45 50 1113.4MGMT, MDM2, STMN1, RB1, EGFR, CDKN2A
8thymidine45 2412.4KDR, PDGFRA, MGMT, STMN1, IGFBP2, CDK4
9oligonucleotide4511.3PDGFRA, TP53, PTEN, CDK4, IGFBP2, RB1
10threonine4511.3CDKN2A, RB1, STMN1, CDK2, MDM2, PTEN
115fluorouracil4511.3CDKN2A, CDK4, CDK2, KDR, PTEN, TP53
12agar4511.3LGALS3, RB1, PTEN, EGFR, CDKN2A, GFAP
13genistein45 29 60 2 11 2416.3MDM2, KDR, MGMT, RB1, CDKN2A, GFAP
14paraffin4511.3MGMT, MDM2, EGFR, CDK4, GFAP, KDR
15arginine4511.2CDKN2A, IGFBP2, MDM2, CDK4, GFAP, TP53
16pd 98,0594511.2GFAP, PTEN, CDKN2B, EGFR, CDK2, RB1
17rapamycin4511.2CDK2, KDR, PTEN, IGFBP2, EGFR, RB1
18phosphatidylinositol4511.2EGFR, IGFBP2, RB1, CDK4, MDM2, PDGFRA
19ly2940024511.2KDR, TP53, PTEN, MDM2, CDK2, CDK4
20thymidylate4511.2EGFR, RB1, CDKN2A, CDK4, CDK2, TP53
21camptothecin45 60 1113.2TP53, KDR, CDK2, RB1, MGMT, MDM2
22flavopiridol45 1112.2MDM2, RB1, EGFR, CDKN2A, CDK4, CDK2
23carboplatin45 50 1113.2CDK4, RB1, TP53, MDM2, MGMT, EGFR
24oxygen45 2412.1IGFBP2, GFAP, LGALS3, CDK4, CDKN2A, RB1
25testosterone45 60 11 2414.1EGFR, CDK2, IGFBP2, RB1, MDM2, PTEN
26mg 13245 6012.1PTEN, KDR, TP53, CDKN2A, EGFR, CDK2
27serine4511.1GFAP, CDKN2C, CDKN2B, STMN1, DMBT1
28cysteine4511.1LGALS3, CDK4, GFAP, CDKN2A, RB1, KDR
29roscovitine4511.1CDK2, CDK4, CDKN2A, TP53, RB1, MDM2
30trastuzumab45 50 1113.1PTEN, CDK2, CDK4, EGFR, MDM2, KDR
31gefitinib45 50 1113.1EGFR, PTEN, KDR, CDK2, CDK4, MDM2
32olomoucine45 1112.1TP53, CDK2, CDK4, CDKN2A, RB1
33calcium45 50 11 2414.0CDK4, IGFBP2, STMN1, LGALS3, GFAP, DMBT1
34bcnu4511.0GFAP, TP53, MGMT, CDKN2A, EGFR
35adpribose4511.0MDM2, CDK4, TP53, RB1, CDK2, EGFR
36geldanamycin45 50 60 1114.0MDM2, EGFR, KDR, CDK4, TP53, CDK2
37cytarabine45 50 1113.0TP53, CDK2, GFAP, CDKN2B, CDKN2A, RB1
38crcs4511.0CDKN2A, MGMT, TP53, RB1, PTEN
39dexamethasone45 50 29 1114.0RB1, MGMT, MDM2, KDR, CDK2, CDKN2A
40estrogen4511.0GFAP
41etoposide45 50 60 1113.9CDK2, RB1, LGALS3, MDM2
42nitric oxide45 11 2412.9MGMT, CDKN2A, CDK4, CDK2, KDR, PTEN
43cycloheximide4510.8IGFBP2
44tgf beta14510.8CDK4, KDR, CDK2, CDKN2B, PDGFRA, PTEN
45vincristine45 50 1112.8MGMT, RB1
46cyclophosphamide45 50 1112.8PTEN, TP53, MDM2, KDR, RB1, MGMT
47butyrate4510.7GFAP, CDK2
48imatinib45 50 1112.6PTEN, EGFR, MDM2, PDGFRA, CDK2, KDR
49fascaplysin4510.6CDK2, CDK4, CDKN2A
50curcumin4510.4CDK2, MGMT, TP53, MDM2, CDK4, EGFR

GO Terms for genes affiliated with Oligodendroglioma

Sources:
16Gene Ontology
See all sources

Cellular components related to Oligodendroglioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nucleusGO:00563411.3TP53, PDGFRA, MGMT, MDM2, RB1, EGFR
2cytoplasmGO:00573711.2PDGFRA, MDM2, DMBT1, EGFR, CDKN2A, CDKN2B
3cytosolGO:00582911.0MDM2, STMN1, CDKN2A, CDKN2B, CDK4, CDK2
4nucleoplasmGO:00565410.8MGMT, MDM2, RB1, CDKN2A, CDK4, CDK2
5nuclear bodyGO:01660410.7MDM2, CDKN2A, TP53
6PML bodyGO:01660510.6TP53, PTEN, RB1
7chromatinGO:00078510.5RB1, CDK4, TP53
8cyclin-dependent protein kinase holoenzyme complexGO:00030710.3CDK2, CDK4

Biological processes related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of cell proliferationGO:00828411.1PTEN, KDR, CDK2, CDK4, EGFR, MDM2
2mitotic cell cycleGO:00027811.1RB1, CDKN2A, CDKN2B, CDK4, CDK2, CDKN2C
3modulation by virus of host morphology or physiologyGO:01904811.1PDGFRA, MDM2, DMBT1, RB1, KDR, TP53
4cell cycle arrestGO:00705011.0RB1, CDKN2A, CDKN2B, CDKN2C, TP53
5innate immune responseGO:04508711.0PDGFRA, MDM2, DMBT1, EGFR, PTEN, LGALS3
6negative regulation of cell proliferationGO:00828511.0CDKN2A, CDKN2B, CDKN2C, PTEN, TP53
7Ras protein signal transductionGO:00726511.0RB1, CDKN2A, CDK2, TP53
8phosphatidylinositol-mediated signalingGO:04801511.0PDGFRA, MDM2, EGFR, PTEN
9negative regulation of phosphorylationGO:04232610.9CDKN2A, CDKN2B, CDKN2C
10negative regulation of G1/S transition of mitotic cell cycleGO:200013410.9PTEN, CDKN2B, RB1
11fibroblast growth factor receptor signaling pathwayGO:00854310.9PDGFRA, MDM2, EGFR, PTEN
12positive regulation of fibroblast proliferationGO:04814610.9CDK4, EGFR, PDGFRA
13Fc-epsilon receptor signaling pathwayGO:03809510.9PTEN, EGFR, MDM2, PDGFRA
14negative regulation of epithelial cell proliferationGO:05068010.9PTEN, CDKN2B, RB1
15regulation of cyclin-dependent protein serine/threonine kinase activityGO:00007910.8CDKN2B, CDKN2C, PTEN
16epidermal growth factor receptor signaling pathwayGO:00717310.8PDGFRA, MDM2, EGFR, PTEN
17negative regulation of apoptotic processGO:04306610.8TP53, PTEN, KDR, EGFR, MDM2
18DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrestGO:00697710.7MDM2, CDK2, TP53
19positive regulation of epithelial cell differentiationGO:03085810.7CDKN2B, DMBT1
20mitotic G1 DNA damage checkpointGO:03157110.6CDK2, TP53
21positive regulation of ERK1 and ERK2 cascadeGO:07037410.6KDR, EGFR, PDGFRA
22replicative senescenceGO:09039910.6TP53, CDKN2A
23response to drugGO:04249310.5MGMT, MDM2, IGFBP2, CDK4
24neurotrophin TRK receptor signaling pathwayGO:04801110.3PTEN, EGFR, MDM2, PDGFRA

Molecular functions related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00551511.4IGFBP2, TP53, LGALS3, PTEN, KDR, OLIG1
2protein kinase bindingGO:01990110.9CDKN2B, TP53, PTEN, CDKN2C, CDKN2A
3cyclin-dependent protein serine/threonine kinase inhibitor activityGO:00486110.8CDKN2C, CDKN2B, CDKN2A
4transmembrane receptor protein tyrosine kinase activityGO:00471410.8PDGFRA, KDR, EGFR
5vascular endothelial growth factor bindingGO:03808510.7PDGFRA, KDR
6MDM2/MDM4 family protein bindingGO:09737110.6TP53, CDKN2A
7p53 bindingGO:00203910.6TP53, CDKN2A, MDM2
8receptor signaling protein tyrosine kinase activityGO:00471610.6KDR, EGFR
9vascular endothelial growth factor-activated receptor activityGO:00502110.5PDGFRA, KDR
10enzyme bindingGO:01989910.3MDM2, PTEN, TP53, EGFR

Products for genes affiliated with Oligodendroglioma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Oligodendroglioma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet