MCID: OLG002
MIFTS: 64

Oligodendroglioma malady

Rare diseases, Neuronal diseases, Cancer diseases categories
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Summaries for Oligodendroglioma

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Wikipedia:65 Oligodendrogliomas are a type of glioma that are believed to originate from the oligodendrocytes of the... more...

MalaCards based summary: Oligodendroglioma, also known as oligodendroglial neoplasm, is related to oligoastrocytoma and mixed glioma. An important gene associated with Oligodendroglioma is GFAP (glial fibrillary acidic protein), and among its related pathways are Inhibition of Ribosome Biogenesis by p14(ARF) and TP53 network. The compounds sodium bisulfite and 7,12-dimethylbenz(a)anthracene have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial, and related mouse phenotypes are pigmentation and normal.

Aliases & Classifications for Oligodendroglioma

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Sources:
8Disease Ontology, 42NIH Rare Diseases, 22GTR, 10DISEASES, 44Novoseek, 48Orphanet, 62UMLS, 34MeSH, 39NCIt, 57SNOMED-CT, 63UMLS via Orphanet
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Oligodendroglioma, Aliases & Descriptions:

Name: Oligodendroglioma 8 42 22 10 44 48 62
Oligodendroglial Neoplasm 8 62
 
Oligodendroglial Tumors 44
Oligodendroglial Tumor 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Neuronal diseases


Characteristics (Orphanet epidemiological data):

48
oligodendroglioma:
Inheritance: Sporadic; Age of onset: Variable


External Ids:

Disease Ontology8 DOID:3181
MeSH34 D009837
NCIt39 C3288
UMLS via Orphanet63 C0028945

Related Diseases for Oligodendroglioma

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Diseases in the Oligodendroglioma family:

Adult Oligodendroglioma

Diseases related to Oligodendroglioma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 153)
idRelated DiseaseScoreTop Affiliating Genes
1oligoastrocytoma31.5MGMT, GFAP
2mixed glioma30.8GFAP, PDGFRA
3meningioma30.2CDKN2B, CDKN2C, PTEN, GFAP
4cerebral cavernous malformation30.2PTEN, KDR
5pilocytic astrocytoma30.1MGMT, GFAP, PTEN, LGALS3, CDK4
6gliosarcoma30.1CDK4, PTEN, GFAP
7sarcoma30.1KDR, PDGFRA, MDM2, CDK4
8rhabdomyosarcoma30.1CDK4, MDM2, PDGFRA
9brain cancer30.0GFAP, EGFR
10pituitary adenoma30.0CDKN2B, CDK4, LGALS3, MGMT
11acute lymphoblastic leukemia29.9CDKN2B, CDK4, CDKN2C, CDKN2A
12ependymoma29.9MGMT, GFAP, PDGFRA, MDM2, CDKN2B, EGFR
13medulloblastoma29.7MGMT, DMBT1, GFAP, PDGFRA, CDK4, CDKN2B
14adenoma29.6MGMT, LGALS3, CDKN2A, CDKN2C, CDK4
15leukemia29.4MGMT, KDR, PDGFRA, MDM2, CDKN2A, CDKN2C
16anaplastic oligodendroglioma29.2LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C, CDK4
17breast cancer29.0PTEN, KDR, LGALS3, MDM2, CDK4, EGFR
18astrocytoma28.7MGMT, DMBT1, GFAP, PTEN, KDR, LGALS3
19glioblastoma28.3PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
20melanoma28.0KDR, LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C
21glioblastoma multiforme27.7EGFR, CDKN2B, MGMT, DMBT1, GFAP, PTEN
22cerebritis10.5
23chondroma10.5PDGFRA
24dysembryoplastic neuroepithelial tumor10.4
25spinal cord oligodendroglioma10.4
26burkitt's lymphoma10.4CDKN2B, CDKN2C
27teratoma10.4
28parathyroid adenoma10.4LGALS3, CDKN2C
29hemangioblastoma10.3KDR, GFAP
30endotheliitis10.3
31dedifferentiated liposarcoma10.3MDM2, CDK4
32myxoid liposarcoma10.3CDK4, MDM2
33gliomatosis cerebri10.3PTEN, GFAP
34gemistocytic astrocytoma10.3PTEN, GFAP
35multiple sclerosis10.3
36central neurocytoma10.3
37brain oligodendroglioma10.3
38alveolar rhabdomyosarcoma10.3CDK4, MDM2
39angiosarcoma10.3KDR, PDGFRA
40pleomorphic adenoma10.3MDM2, GFAP
41chordoma10.3GFAP, LGALS3, PDGFRA
42mixed oligodendroglioma-astrocytoma10.3
43neuronitis10.3
44adult oligodendroglioma10.3
45myelodysplastic syndromes10.2CDKN2B, CDKN2C, PDGFRA
46malignant fibroxanthoma10.2CDK4, MDM2
47childhood oligodendroglioma10.2
48extraventricular neurocytoma10.2
49ganglioneuroma10.2GFAP, PTEN
50papillary thyroid carcinoma10.2PTEN, LGALS3

Graphical network of the top 20 diseases related to Oligodendroglioma:



Diseases related to oligodendroglioma

Symptoms for Oligodendroglioma

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Drugs & Therapeutics for Oligodendroglioma

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Drug clinical trials:

Search ClinicalTrials for Oligodendroglioma

Search NIH Clinical Center for Oligodendroglioma

Genetic Tests for Oligodendroglioma

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Genetic tests related to Oligodendroglioma:

id Genetic test Affiliating Genes
1 Oligodendroglioma22

Anatomical Context for Oligodendroglioma

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MalaCards organs/tissues related to Oligodendroglioma:

32
Brain, Spinal cord, Endothelial, Bone, Bone marrow, Temporal lobe, Breast, Cerebellum, Myeloid, B cells, Parietal lobe, Medulla oblongata, Tongue, Pineal, Pituitary

Animal Models for Oligodendroglioma or affiliated genes

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MGI Mouse Phenotypes related to Oligodendroglioma:

36 (show all 24)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011867.9PTEN, PDGFRA, MDM2, CDKN2A, EGFR
2MP:00028737.6EGFR, MDM2, PDGFRA, KDR, PTEN, GFAP
3MP:00030127.5MGMT, KDR, PDGFRA, MDM2, CDKN2A, CDKN2B
4MP:00053887.4PTEN, KDR, LGALS3, PDGFRA, CDKN2A, CDKN2C
5MP:00053867.4GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
6MP:00053707.3PTEN, KDR, MDM2, CDKN2A, CDK4, EGFR
7MP:00053917.3GFAP, PTEN, KDR, CDKN2A, CDK4, EGFR
8MP:00053907.1PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
9MP:00053797.1MGMT, PTEN, PDGFRA, CDKN2A, CDKN2C, CDK4
10MP:00053697.1GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
11MP:00053857.0GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
12MP:00053676.9DMBT1, PTEN, LGALS3, PDGFRA, MDM2, CDKN2C
13MP:00053896.9PTEN, LGALS3, PDGFRA, MDM2, CDKN2A, CDKN2C
14MP:00053806.8DMBT1, PTEN, KDR, PDGFRA, MDM2, CDKN2A
15MP:00053786.7GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A
16MP:00053816.7DMBT1, GFAP, PTEN, LGALS3, PDGFRA, MDM2
17MP:00107716.5PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
18MP:00036316.5GFAP, PTEN, KDR, LGALS3, PDGFRA, MDM2
19MP:00053976.5PTEN, KDR, LGALS3, PDGFRA, MDM2, CDKN2A
20MP:00020066.3EGFR, MGMT, DMBT1, PTEN, PDGFRA, MDM2
21MP:00053875.8LGALS3, KDR, PTEN, GFAP, DMBT1, PDGFRA
22MP:00053845.8LGALS3, KDR, PTEN, GFAP, DMBT1, PDGFRA
23MP:00053765.7KDR, PTEN, GFAP, DMBT1, MGMT, LGALS3
24MP:00107685.3KDR, PTEN, GFAP, DMBT1, MGMT, LGALS3

Publications for Oligodendroglioma

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Articles related to Oligodendroglioma:

(show top 50)    (show all 613)
idTitleAuthorsYear
1
Occipital anaplastic oligodendroglioma with multiple organ metastases after a short clinical course: a case report and literature review. (24447608)
2014
2
Multiple sclerosis and oligodendroglioma: an exceptional association. (25180114)
2014
3
Health-related quality of life and cognitive functioning in long-term anaplastic oligodendroglioma and oligoastrocytoma survivors. (24162809)
2014
4
Short-term survivors in glioblastomas with oligodendroglioma component: a clinical study of 186 Chinese patients from a single institution. (24264532)
2014
5
A case of oligodendroglioma with prominent neuronal differentiation. (24054724)
2013
6
Combining two biomarkers, IDH1/2 mutations and 1p/19q codeletion, to stratify anaplastic oligodendroglioma in three groups: a single-center experience. (23681562)
2013
7
Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and I+-KG. (24252742)
2013
8
1p19q co-deleted oligodendroglioma metastatic to bone. (23073167)
2013
9
BMP Signaling Induces Astrocytic Differentiation of * Clinically-derived Oligodendroglioma Propagating Cells. (24269952)
2013
10
1p/19q codeletion and IDH1/2 mutation identified a subtype of anaplastic oligoastrocytomas with prognosis as favorable as anaplastic oligodendrogliomas. (23486687)
2013
11
Pitfalls of conservative treatments of multiple probable cerebral cavernous malformations (CCMs): clinicopathological features of CCMs coexisting with vasculogenic mimicry in an anaplastic oligodendroglioma. (24337536)
2013
12
iTRAQ-based quantitative proteomic analysis for identification of oligodendroglioma biomarkers related with loss of heterozygosity on chromosomal arm 1p. (23041135)
2012
13
Rare synchronous association of vestibular schwannoma and indolent insular oligodendroglioma in a patient without neurofibromatosis: controversial issue of timing for surgical treatment of asymptomatic low-grade gliomas. (23180968)
2012
14
Multiple courses of stereotactic re-irradiation in recurrent oligodendroglioma: a case report. (21569607)
2011
15
Supratentorial clear cell ependymoma mimicking oligodendroglioma : case report and review of the literature. (22102956)
2011
16
Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. (20236756)
2010
17
Non-stem cell origin for oligodendroglioma. (21156288)
2010
18
Identification of genetic alterations by multiple ligation-dependent probe amplification (MLPA) analysis in oligodendrogliomas]. (19448956)
2009
19
Spinal cord oligodendroglioma with 1p and 19q deletions presenting with cerebral oligodendrogliomatosis. (19558288)
2009
20
Loss of Arf causes tumor progression of PDGFB-induced oligodendroglioma. (17438529)
2007
21
Oligodendroglioma with neurocytic differentiation versus atypical extraventricular neurocytoma: a case report of unusual pathologic findings of a spinal cord tumor. (17039400)
2007
22
Disseminating anaplastic brainstem oligodendroglioma associated with allelic loss in the tumor suppressor candidate region D19S246 of chromosome 19 mimicking an inflammatory central nervous system disease in a 9-year-old boy. (16084959)
2005
23
Anaplastic oligodendroglioma presenting with drop metastases in the cauda equina. (16023538)
2005
24
Spinal epidural metastasis of cerebral oligodendroglioma. (12728479)
2003
25
Tumour necrosis and microvascular proliferation are associated with 9p deletion and CDKN2A alterations in 1p/19q-deleted oligodendrogliomas. (14507338)
2003
26
Allelic losses in oligodendroglial and oligodendroglioma-like neoplasms: analysis using microsatellite repeats and polymerase chain reaction. (14632576)
2003
27
Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics. (12456321)
2003
28
Phase II trial of procarbazine, lomustine, and vincristine as initial therapy for patients with low-grade oligodendroglioma or oligoastrocytoma: efficacy and associations with chromosomal abnormalities. (12525516)
2003
29
Oligodendroglioma. (14585228)
2003
30
CD44H is expressed by cells of the oligodendrocyte lineage and by oligodendrogliomas in humans. (12635659)
2002
31
Expression of hypoxia-inducible factor-1 alpha in oligodendrogliomas: its impact on prognosis and on neoangiogenesis. (11443623)
2001
32
The prognostic significance of DNA topoisomerase II-alpha (Ki-S1), p21/Cip-1, and p27/Kip-1 protein immunoexpression in oligodendrogliomas. (11419973)
2001
33
New perspectives for the diagnosis and treatment of oligodendroglioma. (12113102)
2001
34
Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells. (11589429)
2001
35
Oligodendroglioma: HMB-45 positivity using catalyzed signal amplification method: an immunohistochemical (HMB-45, CD31, p53, Mib-1) and ultrastructural study. (11277413)
2001
36
Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression. (11591848)
2001
37
P18 tumor suppressor gene and progression of oligodendrogliomas to anaplasia. (10994011)
2000
38
Myeloablative chemotherapy for recurrent aggressive oligodendroglioma. (11303620)
2000
39
Evaluation of cell proliferation, epidermal growth factor receptor, and bcl-2 immunoexpression as prognostic factors for patients with World Health Organization grade 2 oligodendroglioma. (10679656)
2000
40
Glial fibrillary acidic protein and its fragments discriminate astrocytoma from oligodendroglioma. (10344289)
1999
41
Clinicohistological study of oligodendroglioma and oligoastrocytoma. (9384800)
1997
42
The ultrastructure of oligodendroglioma: personal experience and the review of the literature. (9812424)
1996
43
Oligodendroglioma of the fourth ventricle with intracranial and spinal oligodendrogliomatosis: a case report. (1388833)
1992
44
Characterization of a cell line derived from a human oligodendroglioma. (1329795)
1992
45
Intramedullary "holocord" oligodendroglioma: case report. (1799150)
1991
46
Oligodendroglioma--a case presentation. (2308753)
1990
47
Primary oligodendroglioma of the lateral ventricle. (2406943)
1990
48
Oligodendroglioma arising in heterotopic brain tissue of the soft palate and nasopharynx. (3605491)
1987
49
Spinal dissemination following operation on cerebral oligodendroglioma. (878921)
1977
50
Intracerebral oligodendroglioma with metastatic involvement of the spinal cord. Case report. (5120009)
1971

Variations for Oligodendroglioma

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Expression for genes affiliated with Oligodendroglioma

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Expression patterns in normal tissues for genes affiliated with Oligodendroglioma

Search GEO for disease gene expression data for Oligodendroglioma.

Pathways for genes affiliated with Oligodendroglioma

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Pathways related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 58)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CDKN2A, MDM2
2
Show member pathways
9.5CDKN2A, MDM2
3
Show member pathways
Cell cycle Role of SCF complex in cell cycle regulation60
9.4CDKN2A, CDK4, CDKN2B
49.2CDKN2B, CDK4, PTEN
5
Show member pathways
Prostate Cancer37
Integrated Cancer pathway37
Steroid Biosynthesis37
9.1CDK4, MDM2, PTEN
6
Show member pathways
9.1PTEN, MDM2, CDK4
7
Show member pathways
9.1CDKN2B, CDK4, CDKN2C, CDKN2A
88.9MDM2, CDKN2A, CDK4, CDKN2B
98.9KDR, PDGFRA, EGFR
10
Show member pathways
8.9KDR, PDGFRA, EGFR
118.9CDKN2A, MDM2, PTEN
12
Show member pathways
DNA damage response (only ATM dependent)37
Wnt Signaling Pathway and Pluripotency37
8.9PTEN, MDM2, CDKN2A
138.9CDK4, CDKN2A, MDM2, KDR
148.8GFAP, LGALS3, CDK4, EGFR
158.7PDGFRA, CDKN2A, CDKN2C, CDK4, CDKN2B
16
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
178.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
18
Show member pathways
Cell cycle37
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
19
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
20
Show member pathways
8.7MDM2, CDKN2A, CDKN2C, CDK4, CDKN2B
218.6EGFR, MDM2, PTEN
228.6EGFR, MDM2, PTEN
23
Show member pathways
Signal transduction PTEN pathway60
8.6EGFR, MDM2, PTEN
24
Show member pathways
Translation Non genomic rapid action of Androgen Receptor60
8.6PTEN, MDM2, EGFR
25
Show member pathways
DNA damage response37
8.6CDK4, CDKN2A, MDM2, PTEN
268.5KDR, PDGFRA, MDM2, EGFR
27
Show member pathways
8.5KDR, PDGFRA, MDM2, EGFR
28
Show member pathways
8.5MGMT, MDM2, CDKN2A, CDKN2C, CDK4
29
Show member pathways
8.4EGFR, CDK4, CDKN2A, MDM2
30
Show member pathways
PLK2 and PLK4 events37
Polo-like kinase signaling events in the cell cycle37
8.3EGFR, CDKN2B, MDM2, PTEN
31
Show member pathways
Integrin-mediated cell adhesion37
Focal Adhesion37
8.3EGFR, PDGFRA, KDR, PTEN
32
Show member pathways
8.3EGFR, PDGFRA, KDR, PTEN
338.3EGFR, CDK4, MDM2, PTEN
34
Show member pathways
8.3EGFR, MDM2, PDGFRA, PTEN
35
Show member pathways
8.3PTEN, PDGFRA, MDM2, EGFR
36
Show member pathways
8.0GFAP, PTEN, PDGFRA, MDM2, EGFR
378.0PTEN, PDGFRA, MDM2, CDKN2B, EGFR
38
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
39
Show member pathways
7.9PTEN, KDR, PDGFRA, MDM2, EGFR
407.8PTEN, PDGFRA, MDM2, CDKN2A, EGFR
417.7PTEN, PDGFRA, MDM2, CDK4, CDKN2B, EGFR
427.6PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
437.6PTEN, KDR, PDGFRA, MDM2, CDK4, EGFR
44
Show member pathways
7.4PTEN, KDR, PDGFRA, MDM2, CDKN2A, EGFR
45
Show member pathways
7.4GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2B
467.2PTEN, PDGFRA, MDM2, CDKN2A, CDK4, CDKN2B
47
Show member pathways
7.1KDR, PDGFRA, MDM2, CDKN2A, CDKN2C, CDK4
487.0MGMT, PTEN, PDGFRA, MDM2, CDKN2A, CDK4
49
Show member pathways
Signaling Pathways in Glioblastoma37
6.9EGFR, PTEN, PDGFRA, MDM2, CDKN2A, CDKN2C
50
Show member pathways
6.3GFAP, PTEN, KDR, PDGFRA, MDM2, CDKN2A

Compounds for genes affiliated with Oligodendroglioma

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Compounds related to Oligodendroglioma according to GeneCards/GeneDecks:

(show top 50)    (show all 129)
idCompoundScoreTop Affiliating Genes
1sodium bisulfite449.4CDKN2A, MGMT, CDKN2B
27,12-dimethylbenz(a)anthracene449.3CDKN2A, MGMT, MDM2
35-methylcytosine44 2410.1CDKN2A, CDKN2B, MGMT
4hematoxylin449.1GFAP, PTEN, LGALS3, CDKN2A
5sunitinib44 50 1110.9EGFR, KDR, PDGFRA
6tgf beta1448.9PDGFRA, CDK4, PTEN, KDR, CDKN2B
7bcnu448.8MGMT, EGFR, CDKN2A, GFAP
8camptothecin44 61 1110.8MGMT, CDKN2A, KDR, CDK4, MDM2
9geldanamycin44 50 61 1111.8EGFR, MDM2, KDR, CDK4
10flavopiridol44 119.7CDKN2A, CDK4, EGFR, MDM2
11thymidine44 249.6MGMT, KDR, PDGFRA, MDM2, CDK4, GFAP
12glycogen44 249.6LGALS3, MDM2, CDK4, GFAP, PTEN
135-methylthioadenosine448.6EGFR, CDKN2B, CDKN2A
14vincristine44 50 1110.5CDKN2A, PTEN, MGMT, MDM2
15irinotecan44 50 1110.5CDKN2A, EGFR, MDM2, MGMT
165-aza-2deoxycytidine448.5MDM2, PTEN, MGMT, CDKN2B, CDKN2A
17carboplatin44 50 1110.5MDM2, CDK4, MGMT, EGFR, KDR
18egcg448.4EGFR, CDKN2A, MGMT, CDK4, KDR
19thymidylate448.3MDM2, CDKN2A, MGMT, CDK4, EGFR
20trastuzumab44 50 1110.3EGFR, PTEN, CDK4, KDR, MDM2
21gefitinib44 50 1110.3PTEN, KDR, MDM2, CDK4, EGFR
22dexamethasone44 50 28 1111.3CDK4, MDM2, KDR, GFAP, CDKN2A, MGMT
23phosphotyrosine448.3PTEN, EGFR, PDGFRA, KDR, CDK4
24imatinib44 50 1110.2KDR, MDM2, PTEN, PDGFRA, EGFR
25pd 98,059448.2GFAP, MDM2, CDK4, CDKN2B, EGFR, PTEN
26mg 13244 619.1MDM2, PTEN, EGFR, KDR, CDKN2A
27ly294002448.0KDR, CDK4, EGFR, PTEN, MDM2
28arginine448.0CDKN2A, LGALS3, GFAP, PTEN, CDK4, MDM2
29rapamycin448.0PTEN, EGFR, CDK4, MDM2, PDGFRA, KDR
30threonine447.9MDM2, PTEN, GFAP, LGALS3, CDKN2A, CDKN2C
31oligonucleotide447.9CDKN2A, CDK4, LGALS3, PDGFRA, MDM2, PTEN
32cycloheximide447.8CDK4, MDM2, GFAP, PTEN, EGFR, CDKN2A
33nitric oxide44 24 119.8MDM2, LGALS3, CDK4, KDR, PTEN, MGMT
34testosterone44 61 24 1110.8MDM2, PTEN, CDK4, EGFR, CDKN2A, GFAP
35phosphatidylinositol447.6EGFR, KDR, LGALS3, MDM2, PTEN, CDK4
365fluorouracil447.4MGMT, CDK4, MDM2, PTEN, EGFR, CDKN2A
37doxorubicin44 50 119.4MGMT, MDM2, CDKN2A, CDK4, EGFR, KDR
38agar447.3GFAP, CDKN2A, PTEN, KDR, LGALS3, CDK4
39progesterone44 28 61 24 1111.2MGMT, LGALS3, EGFR, CDK4, CDKN2A, MDM2
40tyrosine447.1PTEN, PDGFRA, KDR, EGFR, CDKN2B, LGALS3
41paclitaxel44 50 119.1PTEN, MDM2, CDKN2A, CDK4, EGFR, KDR
42genistein44 28 61 2 24 1112.1PTEN, EGFR, CDK4, CDKN2A, MDM2, KDR
43cysteine447.1PTEN, DMBT1, GFAP, KDR, LGALS3, MDM2
44calcium44 50 24 1110.0LGALS3, GFAP, PDGFRA, DMBT1, MGMT, MDM2
45cisplatin44 50 61 119.8KDR, CDK4, CDKN2A, MDM2, LGALS3, PTEN
46retinoic acid44 247.6CDK4, EGFR, MGMT, CDKN2A, PDGFRA, LGALS3
47paraffin446.5EGFR, GFAP, MGMT, KDR, LGALS3, PDGFRA
48vegf446.5EGFR, MGMT, CDK4, LGALS3, GFAP, PTEN
49estrogen446.2MGMT, CDK4, GFAP, PTEN, KDR, LGALS3
50serine446.2EGFR, CDKN2B, CDKN2A, DMBT1, GFAP, KDR

GO Terms for genes affiliated with Oligodendroglioma

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Cellular components related to Oligodendroglioma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1nuclear bodyGO:0166049.5CDKN2A, MDM2
2cytosolGO:0058297.5GFAP, PTEN, MDM2, CDKN2A, CDKN2C, CDK4
3cytoplasmGO:0057376.0LGALS3, PTEN, GFAP, DMBT1, PDGFRA, MDM2
4nucleusGO:0056345.8EGFR, MGMT, PTEN, KDR, LGALS3, PDGFRA

Biological processes related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 33)
idNameGO IDScoreTop Affiliating Genes
1negative regulation of protein serine/threonine kinase activityGO:07190110.2CDKN2B, CDKN2C
2positive regulation of epithelial cell differentiationGO:03085810.0CDKN2B, DMBT1
3negative regulation of cell cycle arrestGO:07115710.0CDK4, MDM2
4negative regulation of phosphorylationGO:0423269.8CDKN2A, CDKN2C, CDKN2B
5protein destabilizationGO:0316489.7CDKN2A, MDM2
6negative regulation of G1/S transition of mitotic cell cycleGO:20001349.7CDKN2B, PTEN
7long-term synaptic potentiationGO:0602919.7GFAP, PTEN
8cell cycle arrestGO:0070509.7CDKN2B, CDKN2C, CDKN2A
9regulation of cyclin-dependent protein serine/threonine kinase activityGO:0000799.7CDKN2B, CDKN2C, PTEN
10G1/S transition of mitotic cell cycleGO:0000829.6CDKN2A, CDKN2C, CDK4
11extracellular matrix organizationGO:0301989.6GFAP, KDR, LGALS3, PDGFRA
12platelet-derived growth factor receptor signaling pathwayGO:0480089.5PDGFRA, PTEN
13mitotic cell cycleGO:0002789.4CDKN2B, CDK4, CDKN2C, CDKN2A
14positive regulation of fibroblast proliferationGO:0481469.4PDGFRA, CDK4, EGFR
15positive regulation of DNA replicationGO:0457409.3EGFR, PDGFRA
16peptidyl-tyrosine phosphorylationGO:0181089.3KDR, PDGFRA, EGFR
17positive regulation of DNA repairGO:0457399.3EGFR, MGMT
18positive regulation of ERK1 and ERK2 cascadeGO:0703749.3EGFR, PDGFRA, KDR
19positive regulation of cell migrationGO:0303359.2KDR, PDGFRA, EGFR
20regulation of protein stabilityGO:0316479.2PTEN, CDKN2A
21protein autophosphorylationGO:0467779.2EGFR, PDGFRA, KDR
22negative regulation of cell proliferationGO:0082859.1PTEN, CDKN2A, CDKN2C, CDKN2B
23response to drugGO:0424939.0CDK4, MDM2, PTEN, MGMT
24viral processGO:0160329.0DMBT1, KDR, PDGFRA, MDM2
25learning or memoryGO:0076118.7EGFR, PTEN
26phosphatidylinositol-mediated signalingGO:0480158.7EGFR, MDM2, PDGFRA, PTEN
27fibroblast growth factor receptor signaling pathwayGO:0085438.7PTEN, PDGFRA, MDM2, EGFR
28Fc-epsilon receptor signaling pathwayGO:0380958.7PTEN, PDGFRA, MDM2, EGFR
29epidermal growth factor receptor signaling pathwayGO:0071738.7EGFR, MDM2, PDGFRA, PTEN
30neurotrophin TRK receptor signaling pathwayGO:0480118.6PTEN, PDGFRA, MDM2, EGFR
31negative regulation of apoptotic processGO:0430668.5PTEN, KDR, MDM2, EGFR
32positive regulation of cell proliferationGO:0082848.0EGFR, CDK4, MDM2, PDGFRA, KDR, PTEN
33innate immune responseGO:0450877.9DMBT1, PTEN, LGALS3, PDGFRA, MDM2, EGFR

Molecular functions related to Oligodendroglioma according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1vascular endothelial growth factor bindingGO:0380859.9PDGFRA, KDR
2vascular endothelial growth factor-activated receptor activityGO:0050219.8KDR, PDGFRA
3cyclin-dependent protein serine/threonine kinase inhibitor activityGO:0048619.6CDKN2B, CDKN2C, CDKN2A
4platelet-derived growth factor receptor bindingGO:0051619.2PDGFRA, PTEN
5receptor signaling protein tyrosine kinase activityGO:0047169.2KDR, EGFR
6transmembrane receptor protein tyrosine kinase activityGO:0047149.1KDR, PDGFRA, EGFR
7integrin bindingGO:0051789.0EGFR, KDR, GFAP
8enzyme bindingGO:0198998.6EGFR, MDM2, PTEN
9protein kinase bindingGO:0199018.2PTEN, CDKN2A, CDKN2C, CDKN2B, EGFR
10protein bindingGO:0055155.9DMBT1, PTEN, KDR, LGALS3, PDGFRA, MDM2

Products for genes affiliated with Oligodendroglioma

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  • Antibodies
  • Proteins
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Sources for Oligodendroglioma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet