Aliases & Classifications for Oligohydramnios

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Sources:
9Disease Ontology, 11DISEASES, 43Novoseek, 60UMLS, 55SNOMED-CT, 27ICD9CM, 33MeSH, 25ICD10
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Oligohydramnios, Aliases & Descriptions:

Name: Oligohydramnios 9 11 43 60
Oligohydramnios - Delivered 9 60
Oligohydramnios, Antepartum Condition or Complication 60
 
Antepartum Oligohydramnios 9
Delivered Oligohydramnios 9


Classifications:



External Ids:

Disease Ontology9 DOID:12215
ICD9CM27 658.0
MeSH33 D016104
ICD1025 O41.0

Summaries for Oligohydramnios

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Disease Ontology:9 A placenta disease that is characterized by a deficiency of amniotic fluid sometimes resulting in an embryonic defect through adherence between embryo and amnion.

MalaCards based summary: Oligohydramnios, also known as oligohydramnios - delivered, is related to polyhydramnios and diabetes insipidus. An important gene associated with Oligohydramnios is NAGLU (N-acetylglucosaminidase, alpha), and among its related pathways are Physiological and Pathological Hypertrophy of the Heart and Sympathetic Nerve Pathway (Neuroeffector Junction). The compounds aliskiren and omapatrilat have been mentioned in the context of this disorder. Affiliated tissues include lung, placenta and kidney, and related mouse phenotypes are nervous system and behavior/neurological.

Wikipedia:63 Oligohydramnios is a condition in pregnancy characterized by a deficiency of amniotic fluid. It is the... more...

Related Diseases for Oligohydramnios

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Diseases related to Oligohydramnios via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 203)
idRelated DiseaseScoreTop Affiliating Genes
1polyhydramnios31.4AFP, AQP1, OXT
2diabetes insipidus30.6OXT
3renal tubular dysgenesis30.5REN, AGT, AGTR1
4edwards syndrome30.4CGA, AFP
5placental abruption30.3SERPINH1, AFP
6kidney disease29.6AQP1, REN, AGT, AGTR1
7endodermal sinus tumor10.5AFP
8fibromuscular dysplasia10.5REN
9congestive heart failure10.5REN
10potter's syndrome10.5
11hypoaldosteronism10.5REN
12testicular teratoma10.4AFP, CGA
13ovarian mixed germ cell neoplasm10.4AFP, CGA
14diabetes insipidus, nephrogenic10.4AQP1, OXT
15anencephaly10.4AFP, CGA
16germinoma10.4AFP, CGA
17germ cell cancer10.4AFP, CGA
18endometritis10.4SERPINH1, OXT
19orthostatic intolerance10.4AGTR1
20lipoid nephrosis10.3NAGLU, ADM
21borderline personality disorder10.3OXT, CGA
22dysgerminoma10.3CGA, AFP
23urinary tract obstruction10.3ACE, AQP3
24ovarian hyperstimulation syndrome10.3REN, CGA
25chorioamnionitis10.3SERPINH1, OXT
26hypertension, diastolic10.2REN, ACE
27pure autonomic failure10.2REN, ACE
28gitelman syndrome10.2REN, AGT
29preterm premature rupture of the membranes10.2
30cervicitis10.2
31choriocarcinoma10.2AFP, ADM, OXT, CGA
32meconium aspiration syndrome10.2EDN1, OXT
33hepatorenal syndrome10.1EDN1, REN
34malignant hypertension10.1ADM, REN, ACE
35aortic valve disease 210.1AGT, NPPB
36kawasaki disease10.1NPPB, ADM
37eagle-barrett syndrome10.1
38cerebritis10.1
39bilateral renal agenesis dominant type10.1
40cytomegalovirus infection10.1
41polycystic kidney disease, autosomal dominant10.1AQP1, REN, ACE
42hydrocephalus10.1AQP1, AFP
43adrenal adenoma10.1ADM, REN
44diabetic angiopathy10.1EDN1, NAGLU, ADM
45glomerulonephritis10.1AGTR1, NAGLU, SERPINH1
46vesicoureteral reflux10.1NAGLU, AGT, AGTR1
47focal segmental glomerulosclerosis10.1NAGLU, ACE, AGTR1
48conn's syndrome10.1AGTR1, REN, ADM
49adrenal cortical adenoma10.1ADM, REN, AGTR1
50nephrosclerosis10.0ADM, ACE, AGTR1

Graphical network of the top 20 diseases related to Oligohydramnios:



Diseases related to oligohydramnios

Symptoms for Oligohydramnios

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Drugs & Therapeutics for Oligohydramnios

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Drug clinical trials:

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Search NIH Clinical Center for Oligohydramnios

Genetic Tests for Oligohydramnios

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Anatomical Context for Oligohydramnios

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MalaCards organs/tissues related to Oligohydramnios:

31
Lung, Placenta, Kidney, Fetal lung, Heart, Brain, Bone, Spinal cord, Breast, Skin, Testes, Cervix, Trachea

Animal Models for Oligohydramnios or affiliated genes

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MGI Mouse Phenotypes related to Oligohydramnios:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00036317.9SERPINH1, AQP1, NAGLU, OXT, REN, AGT
2MP:00053867.7AFP, AQP3, AQP1, NAGLU, ADM, OXT
3MP:00053817.7EDN1, SERPINH1, AQP3, AQP8, OXT, TREH
4MP:00053797.4EDN1, AFP, AQP8, AQP1, OXT, ACE
5MP:00053787.3SERPINH1, AQP3, AQP1, NAGLU, OXT, REN
6MP:00053897.2AFP, AQP8, AQP1, ADM, OXT, REN
7MP:00107686.8AQP1, AQP3, SERPINH1, AFP, EDN1, NAGLU
8MP:00053856.8NAGLU, AQP1, AQP3, SERPINH1, EDN1, ADM
9MP:00053676.3TREH, EDN1, AQP3, AQP8, AQP1, NAGLU
10MP:00053766.0AQP1, AQP8, AQP3, AFP, EDN1, ADM

Publications for Oligohydramnios

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Articles related to Oligohydramnios:

(show top 50)    (show all 419)
idTitleAuthorsYear
1
Intra-vaginal prostaglandin E2 versus double-balloon catheter for labor induction in term oligohydramnios. (25275693)
2014
2
Which is the safer method of labor induction for oligohydramnios women? Transcervical double balloon catheter or dinoprostone vaginal insert. (24397441)
2014
3
The association between isolated oligohydramnios at term and pregnancy outcome. (24925346)
2014
4
Fetal swallowing as a protective mechanism against oligohydramnios and polyhydramnios in late gestation sheep. (22872543)
2013
5
Oligohydramnios associated with sonographically normal kidneys. (22088568)
2012
6
Short-term outcome among term singleton infants with intrapartum oligohydramnios. (22404314)
2012
7
Spontaneous antepartum vesicouterine fistula causing severe oligohydramnios in a patient with a previous cesarean delivery. (22837297)
2012
8
Placental pathologies associated with intra-uterine fetal growth restriction complicated with and without oligohydramnios. (19194718)
2009
9
Contemporary neonatal outcome following rupture of membranes prior to 25 weeks with prolonged oligohydramnios. (19108959)
2009
10
Herceptin (trastuzumab) therapy in a twin pregnancy with associated oligohydramnios. (19398090)
2009
11
Intrapartum fetal heart rate pattern in oligohydramnios. (18765941)
2008
12
Intrauterine growth restriction and oligohydramnios among high-risk patients. (17447191)
2007
13
Isolated oligohydramnios in term pregnancy as an indication for induction of labor. (17437223)
2007
14
A randomized clinical trial comparing the effect of maternal intravenous hydration and placebo on the amniotic fluid index in oligohydramnios. (17763271)
2007
15
Paris heat wave and oligohydramnios. (15592298)
2004
16
A review of amniotic fluid dynamics and the enigma of isolated oligohydramnios. (12152144)
2002
17
Lack of relationship between variable decelerations during reactive nonstress tests and oligohydramnios. (11414522)
2001
18
Successful enucleation of a necrotizing fibroid causing oligohydramnios and fetal postural deformity in the 25th week of gestation. A case report. (11725739)
2001
19
Role of maternal oral hydration in increasing amniotic fluid volume in pregnant women with oligohydramnios. (11336736)
2001
20
A digynic triploid fetus presenting with intrauterine growth restriction, severe oligohydramnios and relative macrocephaly on prenatal ultrasound. (11169300)
2000
21
Severe oligohydramnios induced by cyclooxygenase-2 inhibitor nimesulide. (11094215)
2000
22
Acute oligohydramnios and deteriorating fetal biophysical profile associated with severe preeclampsia. (10406305)
1999
23
Effect of maternal hydration on oligohydramnios: a comparison of three volume expansion methods. (9764623)
1998
24
Oligohydramnios: sonographic diagnosis and clinical implications. (9199843)
1997
25
Is fetal thoracic compression really the underlying mechanism of lung hypoplasia in oligohydramnios? An experimental study in a rabbit model. (9165252)
1997
26
Prophylactic transabdominal amnioinfusion in oligohydramnios for preterm premature rupture of membranes: increase of amniotic fluid index during latency period. (9415523)
1997
27
Oligohydramnios with amnio-chorionic separation at 15-16 weeks' gestation. (7784368)
1995
28
Transabdominal amnioinfusion in preterm pregnancies complicated by fetal growth restriction, oligohydramnios and umbilical cord compression. (8579780)
1995
29
Acute maternal hydration in third-trimester oligohydramnios: effects on amniotic fluid volume, uteroplacental perfusion, and fetal blood flow and urine output. (7485317)
1995
30
Effects of intracervical prostaglandin E2 on fetal heart rate and uterine activity patterns in the presence of oligohydramnios. (7485313)
1995
31
Oligohydramnios: problems and treatment. (7690990)
1993
32
Transabdominal amnioinfusion for the management of nonlaboring postdates with severe oligohydramnios. (8286032)
1993
33
Long bone development in extrinsic fetal akinesia: an experimental study in rat fetuses subjected to oligohydramnios. (1641814)
1992
34
Late onset severe oligohydramnios associated with genitourinary abnormalities. (1640513)
1992
35
The natural history of oligohydramnios/polyhydramnios sequence in monochorionic diamniotic twins. (12796928)
1992
36
The influence of experimentally produced oligohydramnios on lung growth and pulmonary surfactant content in fetal rabbits. (1812157)
1991
37
Fetal vesicorectal fistula causing oligohydramnios in the second trimester. Case report. (2372530)
1990
38
Oligohydramnios sequence and renal tubular malformation associated with maternal enalapril use. (2301491)
1990
39
Oligohydramnios. (2810473)
1989
40
Sonography of placental abnormalities and oligohydramnios in women with elevated alpha-fetoprotein levels: comparison with control subjects. (2476009)
1989
41
Fetal breathing movements as predictor of favourable pregnancy outcome after oligohydramnios due to membrane rupture in second trimester. (2885600)
1987
42
Congenital cutis laxa syndrome: relation of joint dislocations to oligohydramnios. (3777971)
1986
43
Ultrasound evaluation of amniotic fluid: outcome of pregnancies with severe oligohydramnios. (3515948)
1986
44
Neonatal pulmonary hypoplasia with premature rupture of fetal membranes and oligohydramnios. (4040564)
1985
45
Ultrasound-detected oligohydramnios and fetal outcome. (6731530)
1984
46
Abdominal dynamic study in oligohydramnios with Potter's syndrome. (6370698)
1984
47
Elevated maternal serum alpha-fetoprotein, second-trimester oligohydramnios, and pregnancy outcome. (6192373)
1983
48
Oligohydramnios is a contraindication to amniocentesis. (6102258)
1980
49
Oligohydramnios syndrome and intra-abdominal pregnancy. (830883)
1977
50
Renal agenesis, oligohydramnios and diabetes mellitus. (4891577)
1969

Variations for Oligohydramnios

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Expression for genes affiliated with Oligohydramnios

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Search GEO for disease gene expression data for Oligohydramnios.

Pathways for genes affiliated with Oligohydramnios

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Pathways related to Oligohydramnios according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.7AGT, EDN1
29.6ADM, GPR182
39.4AGT, NPPB, EDN1
4
Show member pathways
9.2AQP1, AQP8, AQP3
5
Show member pathways
9.1REN, ACE, AGT, CGA
6
Show member pathways
9.0AGTR1, AGT, ACE, REN
7
Show member pathways
9.0REN, ACE, AGT, AGTR1
8
Show member pathways
8.8EDN1, OXT, AGT, AGTR1
9
Show member pathways
8.3EDN1, ADM, OXT, AGT, AGTR1, CGA

Compounds for genes affiliated with Oligohydramnios

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Compounds related to Oligohydramnios according to GeneCards Suite gene sharing:

(show top 50)    (show all 216)
idCompoundScoreTop Affiliating Genes
1aliskiren43 1210.4AGT, AGTR1, ACE, REN
2omapatrilat439.3ACE, REN, ADM, EDN1
3saralasin439.3AGT, REN, ACE, AGTR1
4lacidipine439.3EDN1, AGTR1, REN, ACE
5eprosartan43 28 1211.3AGTR1, AGT, ACE, REN
6cilazapril43 1210.2EDN1, REN, AGTR1, ACE
7olmesartan43 28 1211.1AGT, AGTR1, ACE, REN
8fosinopril43 1210.1AGTR1, ACE, NPPB, REN
9lisinopril43 49 24 1212.1ACE, REN, NPPB, AGT, AGTR1
10telmisartan43 28 1211.0NPPB, REN, ACE, AGT, AGTR1
11enalaprilat439.0AGT, EDN1, REN, ACE, NPPB
12trandolapril43 1210.0EDN1, AGTR1, REN, ACE, NPPB
13benazepril43 49 1211.0REN, AGTR1, AGT, ACE
14candesartan43 49 28 1212.0REN, AGT, NPPB, ACE, AGTR1
15amlodipine43 49 24 1212.0REN, ACE, AGT, AGTR1, NPPB
16mannitol43 1210.0AQP1, OXT, CGA, ADM, NAGLU, AQP3
17furosemide43 59 28 49 24 1214.0REN, ACE, AGTR1, NAGLU, NPPB
18chymostatin439.0EDN1, REN, AGT, ACE, AGTR1
19irbesartan43 28 49 1211.9REN, ACE, AGTR1, AGT, EDN1
20diltiazem43 28 49 1211.9AGTR1, AGT, EDN1, REN, ACE
21perindopril43 49 1210.9AGT, AGTR1, NPPB, ACE, REN, NAGLU
22carvedilol43 49 28 1211.8REN, AGTR1, ADM, ACE, EDN1, NPPB
23valsartan43 59 28 1211.7NPPB, REN, AGTR1, AGT, ACE, EDN1
24atenolol43 49 28 24 1212.7EDN1, REN, ACE, NPPB, AGTR1, AGT
25sodium nitroprusside438.7CGA, EDN1, NPPB, AGTR1, AQP1, ADM
26l-nmma438.7EDN1, AGTR1, ADM, AGT, NPPB
27quinapril43 49 1210.6REN, AGTR1, EDN1, ACE
28verapamil43 28 49 24 1212.6AGTR1, CGA, ACE, REN, NAGLU, EDN1
29cgmp43 289.6REN, ADM, AGT, AGTR1, NPPB, EDN1
30enalapril43 49 1210.5NAGLU, REN, ACE, NPPB, AGT, AGTR1
31captopril43 59 49 28 1212.5EDN1, AGTR1, REN, NPPB, ACE, ADM
32ang ii438.5AGTR1, AGT, NPPB, EDN1, ADM, REN
33potassium43 24 1210.4REN, ACE, ADM, NAGLU, AQP1, AGTR1
34phenylephrine43 28 24 1211.4CGA, AGTR1, AGT, NPPB, ADM, EDN1
35cyclosporin a43 28 5910.3ADM, NAGLU, EDN1, CGA, AGTR1, SERPINH1
36nitroglycerin43 129.3AGTR1, NPPB, ACE, REN, OXT, ADM
37losartan43 49 28 1211.3REN, NPPB, AGTR1, AGT, ACE, ADM
38nifedipine43 28 49 1211.3AGTR1, EDN1, NAGLU, OXT, REN, ACE
39prostacyclin438.1AGTR1, ADM, REN, NPPB, AGT, CGA
40steroid438.1NPPB, CGA, AGT, REN, OXT, ADM
41acetylcholine43 49 28 24 1212.0EDN1, ADM, CGA, AGTR1, AGT, ACE
42epinephrine43 24 129.9CGA, AGTR1, AGT, NPPB, REN, OXT
43sodium43 248.8AQP1, EDN1, AFP, NAGLU, ADM, REN
44glucose437.7AFP, AQP1, ADM, REN, ACE, AQP3
45arginine437.6EDN1, AQP1, OXT, REN, NPPB, AGT
46norepinephrine43 24 129.6OXT, REN, ACE, NPPB, AGT, AGTR1
47vegf437.4CGA, AGTR1, AGT, NPPB, EDN1, AFP
48forskolin43 49 129.2AGT, CGA, NPPB, REN, OXT, AQP8
49nitric oxide43 24 129.2AGT, ADM, ACE, REN, OXT, NPPB
50creatinine436.8AGTR1, CGA, AGT, OXT, ADM, NAGLU

GO Terms for genes affiliated with Oligohydramnios

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Cellular components related to Oligohydramnios according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.1ADM, OXT, REN, ACE, NPPB, HHLA1
2extracellular spaceGO:00056156.9AGT, EDN1, AFP, SERPINH1, ADM, OXT

Biological processes related to Oligohydramnios according to GeneCards Suite gene sharing:

(show all 34)
idNameGO IDScoreTop Affiliating Genes
1cGMP biosynthetic processGO:000618210.2NPPB, AQP1
2nitric oxide transportGO:003018510.2EDN1, AQP1
3positive regulation of NAD(P)H oxidase activityGO:003386410.1AGT, AGTR1
4regulation of blood vessel size by renin-angiotensinGO:000203410.1AGT, AGTR1
5regulation of renal sodium excretionGO:003581310.1AGTR1, AGT
6positive regulation of cholesterol esterificationGO:001087310.1AGT, AGTR1
7regulation of renal output by angiotensinGO:000201910.1AGT, ACE
8positive regulation of heart rateGO:001046010.0EDN1, ADM
9body fluid secretionGO:000758910.0EDN1, NPPB
10artery smooth muscle contractionGO:001482410.0AGT, EDN1
11low-density lipoprotein particle remodelingGO:003437410.0AGTR1, AGT
12positive regulation of cellular protein metabolic processGO:003227010.0AGT, AGTR1
13positive regulation of cardiac muscle hypertrophyGO:001061310.0AGT, EDN1
14regulation of systemic arterial blood pressure by renin-angiotensinGO:000308110.0ACE, AGTR1
15drinking behaviorGO:004275610.0REN, OXT
16positive regulation of urine volumeGO:00358109.9EDN1, NPPB
17positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling paGO:00514829.9AGTR1, EDN1
18positive regulation of macrophage derived foam cell differentiationGO:00107449.9AGTR1, AGT
19renin-angiotensin regulation of aldosterone productionGO:00020189.9AGTR1, AGT, REN
20angiotensin maturationGO:00020039.8AGT, ACE, REN
21regulation of blood pressureGO:00082179.7NPPB, ACE, REN
22positive regulation of synapse assemblyGO:00519659.7SRPX2, OXT
23regulation of vasodilationGO:00423129.7ACE, NPPB, AGTR1
24response to lipopolysaccharideGO:00324969.7REN, ADM, EDN1
25middle ear morphogenesisGO:00424749.6NAGLU, EDN1
26water transportGO:00068339.6AQP3, AQP8, AQP1
27regulation of sensory perception of painGO:00519309.5OXT, EDN1
28cell-cell signalingGO:00072679.5EDN1, ADM, AGT, CGA
29kidney developmentGO:00018229.4REN, ACE, AGT, AGTR1
30heart developmentGO:00075079.4EDN1, ADM, OXT
31positive regulation of cytosolic calcium ion concentrationGO:00072049.3EDN1, ADM, OXT, AGTR1
32regulation of vasoconstrictionGO:00192299.3EDN1, ACE, AGT, AGTR1
33positive regulation of renal sodium excretionGO:00358159.3AGT, NPPB, OXT, EDN1
34cell surface receptor signaling pathwayGO:00071669.0EDN1, GPR182, NPPB

Molecular functions related to Oligohydramnios according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00051029.4NPPB, SRPX2, REN, ADM
2bradykinin receptor bindingGO:00317119.3AGTR1, ACE
3water channel activityGO:00152509.1AQP3, AQP8, AQP1
4hormone activityGO:00051798.9CGA, AGT, NPPB, ADM, EDN1

Products for genes affiliated with Oligohydramnios

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Sources for Oligohydramnios

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3CDC
13ExPASy
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24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
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38NCIt
39NDF-RT
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